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Conserved domains on  [gi|295442859|ref|NP_595976|]
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topoisomerase II-associated deadenylation-dependent mRNA-decapping factor [Schizosaccharomyces pombe]

Protein Classification

PAT1 family protein( domain architecture ID 12101978)

PAT1 family protein similar to Schizosaccharomyces pombe DNA topoisomerase 2-associated protein PAT1, an activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation

Gene Ontology:  GO:0003723

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 1-750 0e+00

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


:

Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 852.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859    1 MSFFGFNTTLP-KENMFPN-----------EGQLEEDGIDFEETYDDLGNQLNEAGDELNDETFG-------VSAGSIGR 61
Cdd:pfam09770   1 MSFFGFDTTLPhNTAAPGFsqahdpfaglsGGDDDDDALDFEDTYDGLGDQLDETGDAFNDDTFGgggggddVSAGPVGK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859   62 DFDFSGTTAQASAQLEDEQYQINQQNIFAK----PVKPASSELPQVSRLNGASQFPSRePASTAINK------LSDLQPM 131
Cdd:pfam09770  81 DFDFFGQTAKVSDAIEEEQVRFNRQQPAARaaqsSAQPPASSLPQYQYASQQSQQPSK-PVRTGYEKykepepIPDLQVD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  132 ASIWEniVPEKPAIIP---PEVASLQDRLGaQPSEKVFSLQELEEQLlnSMTAPKPPSQPA--IPIVP------------ 194
Cdd:pfam09770 160 ASLWG--VAPKKAAAPapaPQPAAQPASLP-APSRKMMSLEEVEAAM--RAQAKKPAQQPApaPAQPPaappaqqaqqqq 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  195 -------------------------SEMAAQVTRENISSLDPAisaasignvtfgQPNIPSTTTDFAGLAAPNMVHPSQA 249
Cdd:pfam09770 235 qfppqiqqqqqpqqqpqqpqqhpgqGHPVTILQRPQSPQPDPA------------QPSIQPQAQQFHQQPPPVPVQPTQI 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  250 IPNPVMQPSlvPQMPYPQNGMYNPSVAP--------------------PASLVNLFQQEQliqNQNLDEKRQKLERDH-- 307
Cdd:pfam09770 303 LQNPNRLSA--ARVGYPQNPQPGVQPAPahqahrqqgsfgrqapiithPQQLAQLSEEEK---AAYLDEEAKRAKRNHki 377

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  308 MLMAQCAGLMTRSDKSFIARIQISQLMS----------EDPESDDFYYRVYSIIRG--RKPSEEEASHFIQTYLGPSNNR 375
Cdd:pfam09770 378 FLLSKDNGLMTPQDKNFITRIQLQQLVSatgnpneqgtDASLSEDFYYQVYSQIRGgpRQHPSQPLSNFAQTYLFQTGSR 457

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  376 RRGRR-----SENPMQKLQQQLQRLVSSAKERPKATQLSLEGALGKIAVNTVRTPRQLLNVKRP------TEPASSNSSL 444
Cdd:pfam09770 458 QGGMRrqgrgAENHMQRMEQQVQRAVEAAKNKPKNKQLVIEGSLGKISFSNAKTPKPLLNIKRPessndaHRPGSAKKQR 537

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  445 NNFSGFS-TKKDVLHAIEKVYDLLLDFEQALRKAST-----LETTDQEQIDTWKTTLSEKLESIWKALYINESLeaSSKT 518
Cdd:pfam09770 538 SHSETFSlDRKTILRNIEKVYDTLMKMEDHERKMPPpptedSDPELIEKHMEWRSTLQALNAKLWQELKVHEPI--GSTT 615

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  519 RPPFISIISHPKGMRLLPRLFPHLSKEQQISILKVVVYNFDSLDIVLRGTFdVNGE--LPLDVVSEMSSFTQFIIPPLLT 596
Cdd:pfam09770 616 PHPFIAFLSHPKGKKAIPRIFRHLSQEQRTTILTMIVVHLDQLDVVRGAQV-TDGEtqLNAAMREEIELFSQAVMPSLFT 694

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  597 IVNELDLETINNLFSQLLNRTNAVYLIQTKIGLSFLTLFISRAEILKQSGTVNQNEKEEWENTFNVMFNRVKGHFSTVFP 676
Cdd:pfam09770 695 YVNELGLDIVTGLLGLILTRTNVDLIARTRIGLSMLTMILSRAELLKQSGGGTEQDWEQWEQTYNRFFDRLEPTLPYIFP 774

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295442859  677 PPnaRAYADESYPWEFLAACATAASSEQHFTLVSETRDRVLDNIITSKRAPSEIAVVRISNVNLFLNAMGLDAR 750
Cdd:pfam09770 775 GS--VNTGDDVYVWQFLAAMGIGASPDQQQRLVLAVKDRVMDTVALSKTLPPDMAAQRLGNVNLFMRSIGLDVE 846
 
Name Accession Description Interval E-value
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 1-750 0e+00

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 852.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859    1 MSFFGFNTTLP-KENMFPN-----------EGQLEEDGIDFEETYDDLGNQLNEAGDELNDETFG-------VSAGSIGR 61
Cdd:pfam09770   1 MSFFGFDTTLPhNTAAPGFsqahdpfaglsGGDDDDDALDFEDTYDGLGDQLDETGDAFNDDTFGgggggddVSAGPVGK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859   62 DFDFSGTTAQASAQLEDEQYQINQQNIFAK----PVKPASSELPQVSRLNGASQFPSRePASTAINK------LSDLQPM 131
Cdd:pfam09770  81 DFDFFGQTAKVSDAIEEEQVRFNRQQPAARaaqsSAQPPASSLPQYQYASQQSQQPSK-PVRTGYEKykepepIPDLQVD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  132 ASIWEniVPEKPAIIP---PEVASLQDRLGaQPSEKVFSLQELEEQLlnSMTAPKPPSQPA--IPIVP------------ 194
Cdd:pfam09770 160 ASLWG--VAPKKAAAPapaPQPAAQPASLP-APSRKMMSLEEVEAAM--RAQAKKPAQQPApaPAQPPaappaqqaqqqq 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  195 -------------------------SEMAAQVTRENISSLDPAisaasignvtfgQPNIPSTTTDFAGLAAPNMVHPSQA 249
Cdd:pfam09770 235 qfppqiqqqqqpqqqpqqpqqhpgqGHPVTILQRPQSPQPDPA------------QPSIQPQAQQFHQQPPPVPVQPTQI 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  250 IPNPVMQPSlvPQMPYPQNGMYNPSVAP--------------------PASLVNLFQQEQliqNQNLDEKRQKLERDH-- 307
Cdd:pfam09770 303 LQNPNRLSA--ARVGYPQNPQPGVQPAPahqahrqqgsfgrqapiithPQQLAQLSEEEK---AAYLDEEAKRAKRNHki 377

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  308 MLMAQCAGLMTRSDKSFIARIQISQLMS----------EDPESDDFYYRVYSIIRG--RKPSEEEASHFIQTYLGPSNNR 375
Cdd:pfam09770 378 FLLSKDNGLMTPQDKNFITRIQLQQLVSatgnpneqgtDASLSEDFYYQVYSQIRGgpRQHPSQPLSNFAQTYLFQTGSR 457

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  376 RRGRR-----SENPMQKLQQQLQRLVSSAKERPKATQLSLEGALGKIAVNTVRTPRQLLNVKRP------TEPASSNSSL 444
Cdd:pfam09770 458 QGGMRrqgrgAENHMQRMEQQVQRAVEAAKNKPKNKQLVIEGSLGKISFSNAKTPKPLLNIKRPessndaHRPGSAKKQR 537

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  445 NNFSGFS-TKKDVLHAIEKVYDLLLDFEQALRKAST-----LETTDQEQIDTWKTTLSEKLESIWKALYINESLeaSSKT 518
Cdd:pfam09770 538 SHSETFSlDRKTILRNIEKVYDTLMKMEDHERKMPPpptedSDPELIEKHMEWRSTLQALNAKLWQELKVHEPI--GSTT 615

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  519 RPPFISIISHPKGMRLLPRLFPHLSKEQQISILKVVVYNFDSLDIVLRGTFdVNGE--LPLDVVSEMSSFTQFIIPPLLT 596
Cdd:pfam09770 616 PHPFIAFLSHPKGKKAIPRIFRHLSQEQRTTILTMIVVHLDQLDVVRGAQV-TDGEtqLNAAMREEIELFSQAVMPSLFT 694

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  597 IVNELDLETINNLFSQLLNRTNAVYLIQTKIGLSFLTLFISRAEILKQSGTVNQNEKEEWENTFNVMFNRVKGHFSTVFP 676
Cdd:pfam09770 695 YVNELGLDIVTGLLGLILTRTNVDLIARTRIGLSMLTMILSRAELLKQSGGGTEQDWEQWEQTYNRFFDRLEPTLPYIFP 774

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295442859  677 PPnaRAYADESYPWEFLAACATAASSEQHFTLVSETRDRVLDNIITSKRAPSEIAVVRISNVNLFLNAMGLDAR 750
Cdd:pfam09770 775 GS--VNTGDDVYVWQFLAAMGIGASPDQQQRLVLAVKDRVMDTVALSKTLPPDMAAQRLGNVNLFMRSIGLDVE 846
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 68-267 4.14e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.92  E-value: 4.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859   68 TTAQASAQLEDEQYQINQQNIFAKPVKPASSELPQVSrlngaSQFPSREPASTAINKLSDLQPMASIWENIVP---EKPA 144
Cdd:PRK10263  414 QPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAE-----EQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPqpvEQQP 488

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  145 IIPPEVASLQDRLGAQPsekVFSLQELEE------QLLNSMTAPKP-PSQPAIPIVPSemaaqVTRENISSLDPAISAAS 217
Cdd:PRK10263  489 VVEPEPVVEETKPARPP---LYYFEEVEEkrarerEQLAAWYQPIPePVKEPEPIKSS-----LKAPSVAAVPPVEAAAA 560

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 295442859  218 IGNVTFGQPNIPSTTTDFAGLAAPNMVHPSQAIPNPVMQPSLVPQMPYPQ 267
Cdd:PRK10263  561 VSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPK 610
 
Name Accession Description Interval E-value
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 1-750 0e+00

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 852.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859    1 MSFFGFNTTLP-KENMFPN-----------EGQLEEDGIDFEETYDDLGNQLNEAGDELNDETFG-------VSAGSIGR 61
Cdd:pfam09770   1 MSFFGFDTTLPhNTAAPGFsqahdpfaglsGGDDDDDALDFEDTYDGLGDQLDETGDAFNDDTFGgggggddVSAGPVGK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859   62 DFDFSGTTAQASAQLEDEQYQINQQNIFAK----PVKPASSELPQVSRLNGASQFPSRePASTAINK------LSDLQPM 131
Cdd:pfam09770  81 DFDFFGQTAKVSDAIEEEQVRFNRQQPAARaaqsSAQPPASSLPQYQYASQQSQQPSK-PVRTGYEKykepepIPDLQVD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  132 ASIWEniVPEKPAIIP---PEVASLQDRLGaQPSEKVFSLQELEEQLlnSMTAPKPPSQPA--IPIVP------------ 194
Cdd:pfam09770 160 ASLWG--VAPKKAAAPapaPQPAAQPASLP-APSRKMMSLEEVEAAM--RAQAKKPAQQPApaPAQPPaappaqqaqqqq 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  195 -------------------------SEMAAQVTRENISSLDPAisaasignvtfgQPNIPSTTTDFAGLAAPNMVHPSQA 249
Cdd:pfam09770 235 qfppqiqqqqqpqqqpqqpqqhpgqGHPVTILQRPQSPQPDPA------------QPSIQPQAQQFHQQPPPVPVQPTQI 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  250 IPNPVMQPSlvPQMPYPQNGMYNPSVAP--------------------PASLVNLFQQEQliqNQNLDEKRQKLERDH-- 307
Cdd:pfam09770 303 LQNPNRLSA--ARVGYPQNPQPGVQPAPahqahrqqgsfgrqapiithPQQLAQLSEEEK---AAYLDEEAKRAKRNHki 377

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  308 MLMAQCAGLMTRSDKSFIARIQISQLMS----------EDPESDDFYYRVYSIIRG--RKPSEEEASHFIQTYLGPSNNR 375
Cdd:pfam09770 378 FLLSKDNGLMTPQDKNFITRIQLQQLVSatgnpneqgtDASLSEDFYYQVYSQIRGgpRQHPSQPLSNFAQTYLFQTGSR 457

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  376 RRGRR-----SENPMQKLQQQLQRLVSSAKERPKATQLSLEGALGKIAVNTVRTPRQLLNVKRP------TEPASSNSSL 444
Cdd:pfam09770 458 QGGMRrqgrgAENHMQRMEQQVQRAVEAAKNKPKNKQLVIEGSLGKISFSNAKTPKPLLNIKRPessndaHRPGSAKKQR 537

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  445 NNFSGFS-TKKDVLHAIEKVYDLLLDFEQALRKAST-----LETTDQEQIDTWKTTLSEKLESIWKALYINESLeaSSKT 518
Cdd:pfam09770 538 SHSETFSlDRKTILRNIEKVYDTLMKMEDHERKMPPpptedSDPELIEKHMEWRSTLQALNAKLWQELKVHEPI--GSTT 615

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  519 RPPFISIISHPKGMRLLPRLFPHLSKEQQISILKVVVYNFDSLDIVLRGTFdVNGE--LPLDVVSEMSSFTQFIIPPLLT 596
Cdd:pfam09770 616 PHPFIAFLSHPKGKKAIPRIFRHLSQEQRTTILTMIVVHLDQLDVVRGAQV-TDGEtqLNAAMREEIELFSQAVMPSLFT 694

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  597 IVNELDLETINNLFSQLLNRTNAVYLIQTKIGLSFLTLFISRAEILKQSGTVNQNEKEEWENTFNVMFNRVKGHFSTVFP 676
Cdd:pfam09770 695 YVNELGLDIVTGLLGLILTRTNVDLIARTRIGLSMLTMILSRAELLKQSGGGTEQDWEQWEQTYNRFFDRLEPTLPYIFP 774

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295442859  677 PPnaRAYADESYPWEFLAACATAASSEQHFTLVSETRDRVLDNIITSKRAPSEIAVVRISNVNLFLNAMGLDAR 750
Cdd:pfam09770 775 GS--VNTGDDVYVWQFLAAMGIGASPDQQQRLVLAVKDRVMDTVALSKTLPPDMAAQRLGNVNLFMRSIGLDVE 846
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 68-267 4.14e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.92  E-value: 4.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859   68 TTAQASAQLEDEQYQINQQNIFAKPVKPASSELPQVSrlngaSQFPSREPASTAINKLSDLQPMASIWENIVP---EKPA 144
Cdd:PRK10263  414 QPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAE-----EQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPqpvEQQP 488

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295442859  145 IIPPEVASLQDRLGAQPsekVFSLQELEE------QLLNSMTAPKP-PSQPAIPIVPSemaaqVTRENISSLDPAISAAS 217
Cdd:PRK10263  489 VVEPEPVVEETKPARPP---LYYFEEVEEkrarerEQLAAWYQPIPePVKEPEPIKSS-----LKAPSVAAVPPVEAAAA 560

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 295442859  218 IGNVTFGQPNIPSTTTDFAGLAAPNMVHPSQAIPNPVMQPSLVPQMPYPQ 267
Cdd:PRK10263  561 VSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPK 610
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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