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Conserved domains on  [gi|24584806|ref|NP_609835|]
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cytoplasmic linker protein 190, isoform A [Drosophila melanogaster]

Protein Classification

kinesin family protein; PEPP family PH domain-containing protein( domain architecture ID 13652248)

kinesin family protein is a microtubule-dependent molecular motor that plays an important role in intracellular transport and in cell division and has ATPase-containing motor domain; similar to carboxy-terminal kinesins that contains a C-terminal domain responsible for the motor activity (it hydrolyzes ATP and binds microtubules)| PEPP (phosphoinositol 3-phosphate-binding protein) family PH (pleckstrin homology) domain-containing protein similar to PH domain region of vertebrate pleckstrin homology domain-containing family A member 4/5/6/7

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 239-306 9.93e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.44  E-value: 9.93e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806    239 VGDRVIVSsgfGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKV 306
Cdd:pfam01302    1 VGDRVEVP---GGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 125-189 6.43e-30

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 113.27  E-value: 6.43e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806    125 IGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRL 189
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 638-1491 1.70e-29

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 128.64  E-value: 1.70e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    638 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEklvrem 717
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK------ 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    718 tenaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 797
Cdd:TIGR02168  269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    798 ALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQ 874
Cdd:TIGR02168  345 KLEELKEELESLeaeLEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    875 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 954
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    955 AESRA----------EASDLQDKVKE----------ITDTLHAELQAERSSSSALHTKLSKFSDEIATghkelTSKADAW 1014
Cdd:TIGR02168  485 AQLQArldslerlqeNLEGFSEGVKAllknqsglsgILGVLSELISVDEGYEAAIEAALGGRLQAVVV-----ENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1015 SQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEVTKAKTeNLELSTGTQTTIKDLQERLEIT 1092
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLRK-ALSYLLGGVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1093 NaELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELstvlevlqaeksetnhifelfemeadmnsERLIEKVTG 1172
Cdd:TIGR02168  639 K-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-----------------------------EELEEKIEE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1173 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1252
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1253 IIEAQNTKLNESNVQLENKTSCLKETQDQ-------LLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1325
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEElkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1326 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1405
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1406 TVLESQKKSHNEIQDKL--------EQAQQKERTLQEETSKLAEQLSQLKQ-----------ANEELQKSLQQKQLLLEK 1466
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|....*
gi 24584806   1467 GNEFDTQLAEYQKVIDEMDDAASVK 1491
Cdd:TIGR02168 1009 KEDLTEAKETLEEAIEEIDREARER 1033
NIP100 super family cl34954
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 237-815 1.36e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG5244:

Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 69.33  E-value: 1.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  237 MAVGDRVIVSSGFGsrpgILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFV--------------- 301
Cdd:COG5244    4 LSVNDRVLLGDKFG----TVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIrpdddsllngnaaye 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  302 --------------PIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMR--------MNAQQRKSSTPVKPI 359
Cdd:COG5244   80 kikgglvceskgmdKDGEIKQENHEDRIHFEESKIRRLEETIEALKSTEKEEIVELRreneeldkINLSLRERISSEEPE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  360 LATPKSQFSMQDL--LREKQQHVEKLMVERDLDREDAQNQALQLQKNI--NELKARIVE--------LESALDNERKKTE 427
Cdd:COG5244  160 LNKDGSKLSYDELkeFVEESRVQVYDMVELVSDISETLNRNGSIQRSSvrECERSNIHDvlflvngiLDGVIDELNGELE 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  428 ELQ---CSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLvsATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQkeV 504
Cdd:COG5244  240 RLRrqlVSLMSSHGIEVEENSRLKATLEKFQSLELKVNTL--QEELYQNKLLKKFYQIYEPFAQAALSSQLQYLAEV--I 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  505 ESRIAEQLEeeqrlrenvkylNEQIATLQSELVSKDEALEKFSLSECgiENLRRELELLKEENEKQAQEAQAEFTRKLAE 584
Cdd:COG5244  316 ESENFGKLE------------NIEIHIILKVLSSISYALHIYTIKNT--PDHLETTLQCFVNIAPISMWLSEFLQRKFSS 381

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  585 KSVEVLrlsSELQNLKATSDSLE----------------------SERVNKTDECEILQTEVRMRdeQIRELNQQlDEVT 642
Cdd:COG5244  382 KQETAF---SICQFLEDNKDVTLilkilhpilettvpkllaflrtNSNFNDNDTLCLIGSLYEIA--RIDKLIGK-EEIS 455

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  643 TQLN----VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMT 718
Cdd:COG5244  456 KQDNrlflYPSCDITLSSILTILFSDKLEVFFQGIESLLENITIFPEQPSQQTSDSENIKENSLLSDRLNEENIRLKEVL 535

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  719 ENAINQIQLEKESieQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHE---KL 795
Cdd:COG5244  536 VQKENMLTEETKI--KIIIGRDLERKTLEENIKTLKVELNNKNNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKiylDL 613

                        650       660
                 ....*....|....*....|
gi 24584806  796 QAALEELKKEKETIIKEKEQ 815
Cdd:COG5244  614 VSEIMELRETIRRQIKEQKR 633
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1668-1684 1.31e-06

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 45.92  E-value: 1.31e-06
                           10
                   ....*....|....*..
gi 24584806   1668 RKYCDSCEVFGHDTSEC 1684
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1621-1638 9.54e-05

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.91  E-value: 9.54e-05
                           10
                   ....*....|....*...
gi 24584806   1621 RLFCDICDEFDqHDTEDC 1638
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1429-1598 4.33e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1429 ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL---EKGNEFDTQLAEYQkVIDEMDDAASV--KSALLEQLQNRVA 1503
Cdd:COG4913  220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpirELAERYAAARERLA-ELEYLRAALRLwfAQRRLELLEAELE 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1504 ELETALRQANDAQKtayletkELRRQLESLEleksREVLSLKAQMNGASsrsgkGDEVESLDietslAKINFLNSIIADM 1583
Cdd:COG4913  299 ELRAELARLEAELE-------RLEARLDALR----EELDELEAQIRGNG-----GDRLEQLE-----REIERLERELEER 357

                        170
                 ....*....|....*
gi 24584806 1584 QQKNDALKAKVQTLE 1598
Cdd:COG4913  358 ERRRARLEALLAALG 372
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 2-118 1.47e-03

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806     2 SDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPqpskmkAPSSFGSTGSVSKIGRPCCNHTTP 81
Cdd:PHA03307  280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST------SSSSESSRGAAVSPGPSPSRSPSP 353

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 24584806    82 KSGPPPREATSMSRESDDNLSSINSAYTDNSSAVLTA 118
Cdd:PHA03307  354 SRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRA 390
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 239-306 9.93e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.44  E-value: 9.93e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806    239 VGDRVIVSsgfGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKV 306
Cdd:pfam01302    1 VGDRVEVP---GGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 125-189 6.43e-30

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 113.27  E-value: 6.43e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806    125 IGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRL 189
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 638-1491 1.70e-29

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 128.64  E-value: 1.70e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    638 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEklvrem 717
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK------ 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    718 tenaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 797
Cdd:TIGR02168  269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    798 ALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQ 874
Cdd:TIGR02168  345 KLEELKEELESLeaeLEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    875 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 954
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    955 AESRA----------EASDLQDKVKE----------ITDTLHAELQAERSSSSALHTKLSKFSDEIATghkelTSKADAW 1014
Cdd:TIGR02168  485 AQLQArldslerlqeNLEGFSEGVKAllknqsglsgILGVLSELISVDEGYEAAIEAALGGRLQAVVV-----ENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1015 SQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEVTKAKTeNLELSTGTQTTIKDLQERLEIT 1092
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLRK-ALSYLLGGVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1093 NaELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELstvlevlqaeksetnhifelfemeadmnsERLIEKVTG 1172
Cdd:TIGR02168  639 K-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-----------------------------EELEEKIEE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1173 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1252
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1253 IIEAQNTKLNESNVQLENKTSCLKETQDQ-------LLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1325
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEElkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1326 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1405
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1406 TVLESQKKSHNEIQDKL--------EQAQQKERTLQEETSKLAEQLSQLKQ-----------ANEELQKSLQQKQLLLEK 1466
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|....*
gi 24584806   1467 GNEFDTQLAEYQKVIDEMDDAASVK 1491
Cdd:TIGR02168 1009 KEDLTEAKETLEEAIEEIDREARER 1033
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 239-307 2.68e-29

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 111.91  E-value: 2.68e-29
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806     239 VGDRVIVSSGfgSRPGILRYLGETQFAPGNWCGVELDEP-SGKNDGTVDDIRYFECKPKYGVFVPIAKVS 307
Cdd:smart01052    1 VGDRVEVGGG--GRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1168-1519 3.36e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.72  E-value: 3.36e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1168 EKVTGIKEELKETH-----LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQN 1242
Cdd:COG1196  213 ERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1243 LEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1322
Cdd:COG1196  293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1323 LVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLD 1402
Cdd:COG1196  373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1403 ESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVID 1482
Cdd:COG1196  453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 24584806 1483 EMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1519
Cdd:COG1196  533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 125-190 3.47e-23

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 94.19  E-value: 3.47e-23
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806     125 IGQRVWLGGT-RPGQIAFIGDTHFAAGEWAGVVLDEPN-GKNDGCVSGKRYFQCEPKRGIFSRLTRLT 190
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 667-1540 4.32e-19

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 94.27  E-value: 4.32e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    667 EEKSTLLEKTEKELVQSKEQAAKTL-NDKEQLEKQISDLKQLA-EQEKLVREMTENAINQIQLEKESIEQQLALKQNELE 744
Cdd:pfam02463  186 AELIIDLEELKLQELKLKEQAKKALeYYQLKEKLELEEEYLLYlDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    745 DFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKeketiikeKEQELQQLQSKS 824
Cdd:pfam02463  266 KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK--------AEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    825 AESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 904
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    905 SGHLLEQITKLKSEVGETQaalsschTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERS 984
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEE-------ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    985 SSSALHTKLSKFSDEIATGHKELTSKADawsqemlqkekelqelrqqlqdsqDSQTKLKAEGERKEKSFEESIKNLQEEV 1064
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKD------------------------GVGGRIISAHGRLGDLGVAVENYKVAIS 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1065 TKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAE 1144
Cdd:pfam02463  547 TAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1145 KSETNHIFELFEMEADMNSERLIEKVTGIKEElkethLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQ 1224
Cdd:pfam02463  627 GILKDTELTKLKESAKAKESGLRKGVSLEEGL-----AEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1225 SLQELqdsvKQKEELVQNLEEKVResssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQ 1304
Cdd:pfam02463  702 KKKEQ----REKEELKKLKLEAEE-----LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLK 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1305 QVQEANGDIKDSLVKVEELvkvLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELK 1384
Cdd:pfam02463  773 EKELAEEREKTEKLKVEEE---KEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1385 EALCQKENGLKELQGKLDESNtvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL 1464
Cdd:pfam02463  850 KLAEEELERLEEEITKEELLQ--ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEA 927

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806   1465 EKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSRE 1540
Cdd:pfam02463  928 EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
891-1513 1.60e-18

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 92.41  E-value: 1.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   891 LEAANGSLEE-----EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEkvnkEYAESRAEASDLQ 965
Cdd:PRK02224  182 LSDQRGSLDQlkaqiEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLE----EHEERREELETLE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   966 DKVKEITDTLhAELQAERSS-SSALHTK---LSKFSDEIA-----TGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ 1036
Cdd:PRK02224  258 AEIEDLRETI-AETEREREElAEEVRDLrerLEELEEERDdllaeAGLDDADAEAVEARREELEDRDEELRDRLEECRVA 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1037 DSQTKLKAEGERkeksfeESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEitnaelqhkekmasedaqKIADLKTL 1116
Cdd:PRK02224  337 AQAHNEEAESLR------EDADDLEERAEELREEAAELESELEEAREAVEDRRE------------------EIEELEEE 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1117 VEAIQVANANISATNAELSTVLEVLQAEKSETNHifELFEMEADMNSER-LIEKVTGIKEELK----------ETHLQ-L 1184
Cdd:PRK02224  393 IEELRERFGDAPVDLGNAEDFLEELREERDELRE--REAELEATLRTAReRVEEAEALLEAGKcpecgqpvegSPHVEtI 470

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1185 DERQKKFEELEEKLKQAQqseqklqqESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNEs 1264
Cdd:PRK02224  471 EEDRERVEELEAELEDLE--------EEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE- 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1265 nvqlenktsclketqdqllesqkkekqLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAt 1344
Cdd:PRK02224  542 ---------------------------LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER- 593

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1345 nkeLQELLVKSQENEGNLQgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvlesqkkshneiqDKLEQ 1424
Cdd:PRK02224  594 ---IRTLLAAIADAEDEIE----RLREKREALAELNDERRERLAEKRERKRELEAEFDE----------------ARIEE 650

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1425 AQQKERTLQEETSKLAEQLSQLKQANEELQKSLqqkqlllekgNEFDTQLAEYQKVIDEMDDAASVKSAL------LEQL 1498
Cdd:PRK02224  651 AREDKERAEEYLEQVEEKLDELREERDDLQAEI----------GAVENELEELEELRERREALENRVEALealydeAEEL 720

                         650
                  ....*....|....*
gi 24584806  1499 QNRVAELETALRQAN 1513
Cdd:PRK02224  721 ESMYGDLRAELRQRN 735
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 237-815 1.36e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 69.33  E-value: 1.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  237 MAVGDRVIVSSGFGsrpgILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFV--------------- 301
Cdd:COG5244    4 LSVNDRVLLGDKFG----TVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIrpdddsllngnaaye 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  302 --------------PIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMR--------MNAQQRKSSTPVKPI 359
Cdd:COG5244   80 kikgglvceskgmdKDGEIKQENHEDRIHFEESKIRRLEETIEALKSTEKEEIVELRreneeldkINLSLRERISSEEPE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  360 LATPKSQFSMQDL--LREKQQHVEKLMVERDLDREDAQNQALQLQKNI--NELKARIVE--------LESALDNERKKTE 427
Cdd:COG5244  160 LNKDGSKLSYDELkeFVEESRVQVYDMVELVSDISETLNRNGSIQRSSvrECERSNIHDvlflvngiLDGVIDELNGELE 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  428 ELQ---CSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLvsATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQkeV 504
Cdd:COG5244  240 RLRrqlVSLMSSHGIEVEENSRLKATLEKFQSLELKVNTL--QEELYQNKLLKKFYQIYEPFAQAALSSQLQYLAEV--I 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  505 ESRIAEQLEeeqrlrenvkylNEQIATLQSELVSKDEALEKFSLSECgiENLRRELELLKEENEKQAQEAQAEFTRKLAE 584
Cdd:COG5244  316 ESENFGKLE------------NIEIHIILKVLSSISYALHIYTIKNT--PDHLETTLQCFVNIAPISMWLSEFLQRKFSS 381

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  585 KSVEVLrlsSELQNLKATSDSLE----------------------SERVNKTDECEILQTEVRMRdeQIRELNQQlDEVT 642
Cdd:COG5244  382 KQETAF---SICQFLEDNKDVTLilkilhpilettvpkllaflrtNSNFNDNDTLCLIGSLYEIA--RIDKLIGK-EEIS 455

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  643 TQLN----VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMT 718
Cdd:COG5244  456 KQDNrlflYPSCDITLSSILTILFSDKLEVFFQGIESLLENITIFPEQPSQQTSDSENIKENSLLSDRLNEENIRLKEVL 535

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  719 ENAINQIQLEKESieQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHE---KL 795
Cdd:COG5244  536 VQKENMLTEETKI--KIIIGRDLERKTLEENIKTLKVELNNKNNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKiylDL 613

                        650       660
                 ....*....|....*....|
gi 24584806  796 QAALEELKKEKETIIKEKEQ 815
Cdd:COG5244  614 VSEIMELRETIRRQIKEQKR 633
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 384-805 1.68e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.23  E-value: 1.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    384 MVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITK 463
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    464 lvsatpslqsilppdlpsddgaLQEEIAKLQEKMTiqqkEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEAL 543
Cdd:TIGR02168  752 ----------------------LSKELTELEAEIE----ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL 805

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    544 EKFS--LSECGIENLRRELELLKEENEKQAQEAQAEFTRK-LAEKSVEVLRLSSELQNLKATSDSLESERvnktdecEIL 620
Cdd:TIGR02168  806 DELRaeLTLLNEEAANLRERLESLERRIAATERRLEDLEEqIEELSEDIESLAAEIEELEELIEELESEL-------EAL 878

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    621 QTEVRMRDEQIRELNQQLDEVTTQLNvqkadsSALDDMLRLQKEgteekstlLEKTEKELVQSKEQAAKTLNDKEQLekq 700
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELR------ELESKRSELRRE--------LEELREKLAQLELRLEGLEVRIDNL--- 941

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    701 isdLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFqkkqseSEVHL---QEIKAQNTQKDFelvesges 777
Cdd:TIGR02168  942 ---QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL------GPVNLaaiEEYEELKERYDF-------- 1004

                          410       420
                   ....*....|....*....|....*...
gi 24584806    778 lkkLQQQLEQKTLGHEKLQAALEELKKE 805
Cdd:TIGR02168 1005 ---LTAQKEDLTEAKETLEEAIEEIDRE 1029
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 125-185 1.56e-08

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 59.70  E-value: 1.56e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806  125 IGQRVWLGGTRpGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSR 185
Cdd:COG5244    6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIR 65
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 487-770 3.86e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.13  E-value: 3.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    487 QEEIAKLQEKMTIQQKevesRIAEQLEEEQRLRENVKYLNEQIATLqselVSKDEALEKFSLSECGIENLRRELELLKEE 566
Cdd:pfam17380  332 QAAIYAEQERMAMERE----RELERIRQEERKRELERIRQEEIAME----ISRMRELERLQMERQQKNERVRQELEAARK 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    567 NEKQAQEAQaeftRKLAEKSVEVLRLSSELQNLKATS-DSLESERVNktdECEILQTEVRMRDEQIRELNQQLDEvttql 645
Cdd:pfam17380  404 VKILEEERQ----RKIQQQKVEMEQIRAEQEEARQREvRRLEEERAR---EMERVRLEEQERQQQVERLRQQEEE----- 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    646 nvQKADSSALDDMLRLQKEGTEEKSTLLEKtekELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI 725
Cdd:pfam17380  472 --RKRKKLELEKEKRDRKRAEEQRRKILEK---ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQ 546

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 24584806    726 QL-EKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFE 770
Cdd:pfam17380  547 EMeERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1668-1684 1.31e-06

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 45.92  E-value: 1.31e-06
                           10
                   ....*....|....*..
gi 24584806   1668 RKYCDSCEVFGHDTSEC 1684
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
PRK11281 PRK11281
mechanosensitive channel MscK;
414-824 2.26e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.61  E-value: 2.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   414 ELESALD--NERKKTEE----LQCSIDEAQfcgdELNAQSQVYKEKIHDLESKITKlvsATPSLQSIlppdlpsddgalQ 487
Cdd:PRK11281   40 DVQAQLDalNKQKLLEAedklVQQDLEQTL----ALLDKIDRQKEETEQLKQQLAQ---APAKLRQA------------Q 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   488 EEIAKLQEKM---------TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSelvskdealekfslsecgienlrr 558
Cdd:PRK11281  101 AELEALKDDNdeetretlsTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQT------------------------ 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   559 elellkeenekQAQEAQAEftrkLAEKSVEVLRLSSELQNLKATSDSLESERVNKtdeceiLQTEVRMRDEQIrELNQQL 638
Cdd:PRK11281  157 -----------QPERAQAA----LYANSQRLQQIRNLLKGGKVGGKALRPSQRVL------LQAEQALLNAQN-DLQRKS 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   639 DEVTTQLNvqkadssaldDMLRLQKEGTEEKSTLLEKT---------EKELVQSKEQAAKTLNDKE------------QL 697
Cdd:PRK11281  215 LEGNTQLQ----------DLLQKQRDYLTARIQRLEHQlqllqeainSKRLTLSEKTVQEAQSQDEaariqanplvaqEL 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   698 E--KQISD--------LKQLAEQEKLVREMTENAINQIQLEKESI--------------EQQLALKQNEL-EDFQKKQSE 752
Cdd:PRK11281  285 EinLQLSQrllkatekLNTLTQQNLRVKNWLDRLTQSERNIKEQIsvlkgslllsrilyQQQQALPSADLiEGLADRIAD 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   753 SEVHLQEIkaqNTQKDfELVESGESLKKLQQQleQKTLGHEKLQAALEELKKEKETIIKEKEQEL--------------Q 818
Cdd:PRK11281  365 LRLEQFEI---NQQRD-ALFQPDAYIDKLEAG--HKSEVTDEVRDALLQLLDERRELLDQLNKQLnnqlnlainlqlnqQ 438


                  ....*.
gi 24584806   819 QLQSKS 824
Cdd:PRK11281  439 QLLSVS 444
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1621-1638 9.54e-05

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.91  E-value: 9.54e-05
                           10
                   ....*....|....*...
gi 24584806   1621 RLFCDICDEFDqHDTEDC 1638
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1429-1598 4.33e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1429 ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL---EKGNEFDTQLAEYQkVIDEMDDAASV--KSALLEQLQNRVA 1503
Cdd:COG4913  220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpirELAERYAAARERLA-ELEYLRAALRLwfAQRRLELLEAELE 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1504 ELETALRQANDAQKtayletkELRRQLESLEleksREVLSLKAQMNGASsrsgkGDEVESLDietslAKINFLNSIIADM 1583
Cdd:COG4913  299 ELRAELARLEAELE-------RLEARLDALR----EELDELEAQIRGNG-----GDRLEQLE-----REIERLERELEER 357

                        170
                 ....*....|....*
gi 24584806 1584 QQKNDALKAKVQTLE 1598
Cdd:COG4913  358 ERRRARLEALLAALG 372
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 631-1011 7.80e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 44.23  E-value: 7.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   631 IRELNQQLDEVTTQLNVqkadsSALDDMLRLQKEGTEEKSTLLEKTEKELvqSKEQAAKTLNDKEQLEKQISDL-KQLAE 709
Cdd:NF033838   71 LSEIQKSLDKRKHTQNV-----ALNKKLSDIKTEYLYELNVLKEKSEAEL--TSKTKKELDAAFEQFKKDTLEPgKKVAE 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   710 QEKLVREMTENAINQIQlEKESIEQQLALKQNELE--DFQKKQSESEVHLQEIKAQNTQKDfelvesgESLKKLQQQLEQ 787
Cdd:NF033838  144 ATKKVEEAEKKAKDQKE-EDRRNYPTNTYKTLELEiaESDVEVKKAELELVKEEAKEPRDE-------EKIKQAKAKVES 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   788 KtlgheklQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLK 867
Cdd:NF033838  216 K-------KAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDS 288

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   868 SQAEET--QSELKSTQSNLEAKSKQLEAangslEEEAKksghlleqitKLKSEVGETQAALSSCHTDVESKTKQLEAANA 945
Cdd:NF033838  289 SVGEETlpSPSLKPEKKVAEAEKKVEEA-----KKKAK----------DQKEEDRRNYPTNTYKTLELEIAESDVKVKEA 353

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806   946 ALEKVNKEYAESRAEasdlqDKVKEItdtlhaelQAERSSSSALHTKLSKFSDEIATGHKELTSKA 1011
Cdd:NF033838  354 ELELVKEEAKEPRNE-----EKIKQA--------KAKVESKKAEATRLEKIKTDRKKAEEEAKRKA 406
ClyA-like cd21116
family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including ...
 1197-1345 9.41e-04

family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including Bacillus cereus HblB, Aeromonas hydrophila AhlB, Bacillus thuringiensis Cry6Aa and similar proteins; This family belongs to the ClyA family of alpha-PFT bacterial toxins. PFTs form the major group of virulence factors in many pathogenic bacteria and in general are critical components of the molecular offensive and defensive machinery of cells in all kingdoms of life. Bacterial PFTs facilitate the takeover of host resources by puncturing holes in the membrane. PFTs can be classified as alpha-PFTs and beta-PFTs depending on the secondary structures of their membrane component. Alpha-PFTs use a ring of amphipathic helices while beta-PFTs use a beta-barrel to construct the pore. Members of this family include the toxins: Bacillus cereus hemolysin binding component B (HblB or HBL-B) of the diarrheal enterotoxin hemolysin BL, Aeromonas hydrophila hemolytic (Ahl) component B (AhlB) of the tripartite AhlABC toxin, Vibrio cholerae cytotoxin motility associated killing factor A (MakA) cytotoxin, Xenorhabdus nematophila alpha-xenorhabdolysin (XaxA), Bacillus thuringiensis crystal 6Aa (Cry6Aa) parasporal crystal (Cry) toxin, and Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA) of the non-hemolytic enterotoxin Nhe, which, despite its name, is hemolytic, among others. In solution, ClyA proteins have an elongated, almost entirely alpha-helical structure, except for a short hydrophobic beta-hairpin known as the beta-tongue. Pore formation by ClyA requires circular oligomerization of the toxin by a sequential mechanism. This, in turn, concentrates the amphipathic helices in the center of the ring-like structure, forming a helical barrel that inserts into the membrane by a wedge-like mechanism. Compared with ClyA, NheA is almost entirely alpha-helical with an enlarged "head" domain, and an enlarged beta-tongue; it has been proposed that NheA could even form beta-barrel pores. Alpha-PFTs with similar structures are increasingly being found in eukaryotes, in particular as components of the immune systems of animals. This family may be distantly related to Escherichia coli alpha-PFT hemolysin E (HlyE, also known as ClyA or SheA).


Pssm-ID: 439149 [Multi-domain]  Cd Length: 224  Bit Score: 42.79  E-value: 9.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1197 KLKQAQQSEQKLQQESQTSKEKLteiQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLK 1276
Cdd:cd21116   74 YYPDLIELADNLIKGDQGAKQQL---LQGLEALQSQVTKKQTSVTSFINELTTFKNDLDDDSRNLQTDATKAQAQVAVLN 150

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806 1277 ETQDQLlesqkkeKQLQEEAAKLSGELQQVQEANGDIKDSLvkveelvKVLEEKLQAATSQLDAQQATN 1345
Cdd:cd21116  151 ALKNQL-------NSLAEQIDAAIDALEKLSNDWQTLDSDI-------KELITDLEDAESSIDAAFLQA 205
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1221-1448 1.25e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 43.08  E-value: 1.25e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    1221 EIQQ-SLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQlLESQK-----KEKQLQE 1294
Cdd:smart00787   66 ELYQfSCKELKKYISEGRDLFKEIEEETLINNPPLFKEYFSASPDVKLLMDKQFQLVKTFAR-LEAKKmwyewRMKLLEG 144

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    1295 EAAKLSGELQQVQEAngdiKDSLVKVEELVKVLEEKLQaatsqlDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQ 1374
Cdd:smart00787  145 LKEGLDENLEGLKED----YKLLMKELELLNSIKPKLR------DRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLK 214

                           170       180       190       200       210       220       230
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24584806    1375 QLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTlqeETSKLAEQLSQLKQ 1448
Cdd:smart00787  215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFK---EIEKLKEQLKLLQS 285
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-118 1.47e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806     2 SDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPqpskmkAPSSFGSTGSVSKIGRPCCNHTTP 81
Cdd:PHA03307  280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST------SSSSESSRGAAVSPGPSPSRSPSP 353

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 24584806    82 KSGPPPREATSMSRESDDNLSSINSAYTDNSSAVLTA 118
Cdd:PHA03307  354 SRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRA 390
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 239-306 9.93e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.44  E-value: 9.93e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806    239 VGDRVIVSsgfGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKV 306
Cdd:pfam01302    1 VGDRVEVP---GGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 125-189 6.43e-30

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 113.27  E-value: 6.43e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806    125 IGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRL 189
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 638-1491 1.70e-29

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 128.64  E-value: 1.70e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    638 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEklvrem 717
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK------ 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    718 tenaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 797
Cdd:TIGR02168  269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    798 ALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQ 874
Cdd:TIGR02168  345 KLEELKEELESLeaeLEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    875 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 954
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    955 AESRA----------EASDLQDKVKE----------ITDTLHAELQAERSSSSALHTKLSKFSDEIATghkelTSKADAW 1014
Cdd:TIGR02168  485 AQLQArldslerlqeNLEGFSEGVKAllknqsglsgILGVLSELISVDEGYEAAIEAALGGRLQAVVV-----ENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1015 SQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEVTKAKTeNLELSTGTQTTIKDLQERLEIT 1092
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLRK-ALSYLLGGVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1093 NaELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELstvlevlqaeksetnhifelfemeadmnsERLIEKVTG 1172
Cdd:TIGR02168  639 K-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-----------------------------EELEEKIEE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1173 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1252
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1253 IIEAQNTKLNESNVQLENKTSCLKETQDQ-------LLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1325
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEElkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1326 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1405
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1406 TVLESQKKSHNEIQDKL--------EQAQQKERTLQEETSKLAEQLSQLKQ-----------ANEELQKSLQQKQLLLEK 1466
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|....*
gi 24584806   1467 GNEFDTQLAEYQKVIDEMDDAASVK 1491
Cdd:TIGR02168 1009 KEDLTEAKETLEEAIEEIDREARER 1033
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 239-307 2.68e-29

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 111.91  E-value: 2.68e-29
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806     239 VGDRVIVSSGfgSRPGILRYLGETQFAPGNWCGVELDEP-SGKNDGTVDDIRYFECKPKYGVFVPIAKVS 307
Cdd:smart01052    1 VGDRVEVGGG--GRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 629-1430 4.41e-26

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 117.48  E-value: 4.41e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    629 EQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKE----QLEKQISDL 704
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEeeleKLTEEISEL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    705 KQ--------LAEQEKLVREMTENAINQIQ-------LEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQntqkdf 769
Cdd:TIGR02169  264 EKrleeieqlLEELNKKIKDLGEEEQLRVKekigeleAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAE------ 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    770 elvesgesLKKLQQQLEQKTLGHEKLQAALEELKKEKETIikekEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASG 849
Cdd:TIGR02169  338 --------IEELEREIEEERKRRDKLTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKLKREINELK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    850 EEGSK---TVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAAL 926
Cdd:TIGR02169  406 RELDRlqeELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    927 SSchtdvesKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALhtklskfsdEIATGH-- 1004
Cdd:TIGR02169  486 SK-------LQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAI---------EVAAGNrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1005 KELTSKADAWSQEMLQKEKELQELRQ------QLQDSQDSQTKLKAEG------------ERKEKSFE---------ESI 1057
Cdd:TIGR02169  550 NNVVVEDDAVAKEAIELLKRRKAGRAtflplnKMRDERRDLSILSEDGvigfavdlvefdPKYEPAFKyvfgdtlvvEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1058 KNLQEEVTKAKTENLE---------------LSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQV 1122
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEgelfeksgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1123 ANANISATNAELSTVLEVLQAEKSETNHIFElfEMEADMNSerLIEKVTGIKEELKETHLQLDERQKKFEELEEKL---- 1198
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLE--ELEEDLSS--LEQEIENVKSELKELEARIEELEEDLHKLEEALndle 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1199 --------KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLEN 1270
Cdd:TIGR02169  786 arlshsriPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1271 KTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE 1350
Cdd:TIGR02169  866 LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE 945

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1351 lLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDesntVLESQKKshnEIQDKLEQAQQKER 1430
Cdd:TIGR02169  946 -IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRA----KLEEERK---AILERIEEYEKKKR 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 748-1542 2.26e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 111.69  E-value: 2.26e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    748 KKQSESEVHLQEIKAQNTQKDFELveSGESLKKLQQQLEQKtlghEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES 827
Cdd:TIGR02168  206 ERQAEKAERYKELKAELRELELAL--LVLRLEELREELEEL----QEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    828 ESALKVVQVQLEQLqqqaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGH 907
Cdd:TIGR02168  280 EEEIEELQKELYAL-----------ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    908 LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLhAELQAERSS-- 985
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR-ERLQQEIEEll 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    986 SSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEE 1063
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEG 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1064 VTKAKTENLELSTGTQTtikdLQERLEITNAELQHKEKMASEDAQKIadlktLVEAIQVANANISA---TNAELSTVLE- 1139
Cdd:TIGR02168  508 VKALLKNQSGLSGILGV----LSELISVDEGYEAAIEAALGGRLQAV-----VVENLNAAKKAIAFlkqNELGRVTFLPl 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1140 -VLQAEKSETNHIFELFEMEADMNSERLIEK------------------VTGIKEEL----------------------- 1177
Cdd:TIGR02168  579 dSIKGTEIQGNDREILKNIEGFLGVAKDLVKfdpklrkalsyllggvlvVDDLDNALelakklrpgyrivtldgdlvrpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1178 -------KETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRES 1250
Cdd:TIGR02168  659 gvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL 738

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1251 SSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEK 1330
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1331 LQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEAlcqkengLKELQGKLDESNTVLES 1410
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE-------LEALLNERASLEEALAL 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1411 QKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQkqlLLEKGNEfdtqlaEYQKVIDEMDDAASV 1490
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN---LQERLSE------EYSLTLEEAEALENK 962

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806   1491 KSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE-----LEKSREVL 1542
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTaqkedLTEAKETL 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 500-1459 3.33e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 111.30  E-value: 3.33e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    500 QQKEVESRIAEQLEEEQRLRENVKYLNEQIATL--QSELVSK----DEALEKFSLSECGIE-NLRRELELLKEENEKQAQ 572
Cdd:TIGR02168  173 RRKETERKLERTRENLDRLEDILNELERQLKSLerQAEKAERykelKAELRELELALLVLRlEELREELEELQEELKEAE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    573 EAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLnvQKADS 652
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL--EELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    653 SALDDMLRLQKEGTEekstlLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKlvremteNAINQIQLEKESI 732
Cdd:TIGR02168  331 KLDELAEELAELEEK-----LEELKEELESLEAELEELEAELEELESRLEELEEQLETLR-------SKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    733 eqqlalkQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESgeSLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKE 812
Cdd:TIGR02168  399 -------NNEIERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    813 KEQELQQLQsksaesesalkvvqvqleqlqqqaaasgeegsktvaklhdeisQLKSQAEETQSELKSTQSNLEAKSKQLE 892
Cdd:TIGR02168  470 LEEAEQALD-------------------------------------------AAERELAQLQARLDSLERLQENLEGFSE 506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    893 AANGSLEEEAKKSGHLLEQITKLKSEVGETQA---ALSSCHTDVESKTkqLEAANAALekvnkeyaESRAEASDLQDKVK 969
Cdd:TIGR02168  507 GVKALLKNQSGLSGILGVLSELISVDEGYEAAieaALGGRLQAVVVEN--LNAAKKAI--------AFLKQNELGRVTFL 576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    970 EITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEkELQElrqqlqdsqdsqtklkAEGERK 1049
Cdd:TIGR02168  577 PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD-DLDN----------------ALELAK 639

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1050 EKSFEESIKNLQEE-------VTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQV 1122
Cdd:TIGR02168  640 KLRPGYRIVTLDGDlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1123 ANANISATNAELSTVLEVLQAEksetnhifelfemeadmnSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQ 1202
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAE------------------VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1203 QSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQL 1282
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1283 LESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNL 1362
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1363 QG---ESLAVTEKLQQLEQANGELKEALCQKEngLKELQGKLDESNTV-------LESQKKSHNEIQDKLEQAQQKERTL 1432
Cdd:TIGR02168  942 QErlsEEYSLTLEEAEALENKIEDDEEEARRR--LKRLENKIKELGPVnlaaieeYEELKERYDFLTAQKEDLTEAKETL 1019

                          970       980
                   ....*....|....*....|....*...
gi 24584806   1433 QEETSKL-AEQLSQLKQANEELQKSLQQ 1459
Cdd:TIGR02168 1020 EEAIEEIdREARERFKDTFDQVNENFQR 1047
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 695-1542 1.17e-23

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 109.39  E-value: 1.17e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    695 EQLEKQISDLKQLAEQEKLVREMTENAINQiqLEKESIEQQLALKQNELEDfQKKQSESEVHLQEIKAQNTQK---DFEL 771
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQ--LERLRREREKAERYQALLK-EKREYEGYELLKEKEALERQKeaiERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    772 VESGESLKKLQQQLEQKTLGHEKLQAALEELKKEketIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEE 851
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKK---IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    852 GSKTVAKLHD---EISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLL-------EQITKLKSEVGE 921
Cdd:TIGR02169  324 LAKLEAEIDKllaEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRdelkdyrEKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    922 TQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEIT---DTLHAELQAERSSSSALHTKLSKFSD 998
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEwklEQLAADLSKYEQELYDLKEEYDRVEK 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    999 EIATGHKELTSK---ADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKN-LQ------EEVTKAK 1068
Cdd:TIGR02169  484 ELSKLQRELAEAeaqARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNrLNnvvvedDAVAKEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1069 TENLELSTGTQTTIkdlqerLEITNAELQHKEKMASEDAQKIADLKTLVE-AIQVANANISATNAELstVLEVLQAEKsE 1147
Cdd:TIGR02169  564 IELLKRRKAGRATF------LPLNKMRDERRDLSILSEDGVIGFAVDLVEfDPKYEPAFKYVFGDTL--VVEDIEAAR-R 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1148 TNHIFELFEMEADmnserLIEK---VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQ 1224
Cdd:TIGR02169  635 LMGKYRMVTLEGE-----LFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1225 SLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGEL- 1303
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLs 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1304 -QQVQEangdIKDSLVKVEELVKVLEEKLQaatsqlDAQQATNKELQELLVKSQENEgNLQGESLAVTEKLQQLEQANGE 1382
Cdd:TIGR02169  790 hSRIPE----IQAELSKLEEEVSRIEARLR------EIEQKLNRLTLEKEYLEKEIQ-ELQEQRIDLKEQIKSIEKEIEN 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1383 LKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKslqqkql 1462
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE------- 931

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1463 llekgnefdtQLAEYQKVIDEMDDaASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLesLELEKSREVL 1542
Cdd:TIGR02169  932 ----------ELSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL--DELKEKRAKL 998
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1168-1519 3.36e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.72  E-value: 3.36e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1168 EKVTGIKEELKETH-----LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQN 1242
Cdd:COG1196  213 ERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1243 LEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1322
Cdd:COG1196  293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1323 LVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLD 1402
Cdd:COG1196  373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1403 ESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVID 1482
Cdd:COG1196  453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 24584806 1483 EMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1519
Cdd:COG1196  533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 125-190 3.47e-23

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 94.19  E-value: 3.47e-23
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806     125 IGQRVWLGGT-RPGQIAFIGDTHFAAGEWAGVVLDEPN-GKNDGCVSGKRYFQCEPKRGIFSRLTRLT 190
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 373-1090 2.98e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.75  E-value: 2.98e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    373 LREKQQHVEKL-MVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQfcgDELNAQSQvyk 451
Cdd:TIGR02168  222 LRELELALLVLrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ---KELYALAN--- 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    452 eKIHDLESKITKLVSATPSLQsilppdlpSDDGALQEEIAKLQEKMTIQQKE---VESRIAEQLEEEQRLRENVKYLNEQ 528
Cdd:TIGR02168  296 -EISRLEQQKQILRERLANLE--------RQLEELEAQLEELESKLDELAEElaeLEEKLEELKEELESLEAELEELEAE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    529 IATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSS-ELQNLKATSDSLE 607
Cdd:TIGR02168  367 LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    608 SERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEK--------- 678
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgilgvls 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    679 ELVQSKEQAAKTL-------------NDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELED 745
Cdd:TIGR02168  527 ELISVDEGYEAAIeaalggrlqavvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    746 FQKKQSESEVHLQEI-----------KAQNTQK-----------DFELVESG------------------ESLKKLQQQL 785
Cdd:TIGR02168  607 LVKFDPKLRKALSYLlggvlvvddldNALELAKklrpgyrivtlDGDLVRPGgvitggsaktnssilerrREIEELEEKI 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    786 EQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESeSALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQ 865
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI-SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    866 LKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANA 945
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    946 ALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSdeiatghkELTSKADAWSQEMLQKEKEL 1025
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE--------ELSEELRELESKRSELRREL 917

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806   1026 QELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLE 1090
Cdd:TIGR02168  918 EELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 863-1506 1.60e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 102.32  E-value: 1.60e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  863 ISQLKSQAEETQSELKSTQSNLE-------AKSKQLEaangSLEEEAKKsghlLEQITKLKSEVGETQAALS-----SCH 930
Cdd:COG1196  167 ISKYKERKEEAERKLEATEENLErledilgELERQLE----PLERQAEK----AERYRELKEELKELEAELLllklrELE 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  931 TDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALhtklskfsDEIATGHKELTSK 1010
Cdd:COG1196  239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL--------ARLEQDIARLEER 310

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1011 ADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLE 1090
Cdd:COG1196  311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1091 ITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSEtnhifELFEMEADMNSERLIEKV 1170
Cdd:COG1196  391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA-----AEEEAELEEEEEALLELL 465

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1171 TGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVkqkEELVQNLEEKVRES 1250
Cdd:COG1196  466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV---LIGVEAAYEAALEA 542

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1251 SSIIEAQNtKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEK 1330
Cdd:COG1196  543 ALAAALQN-IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1331 LQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvles 1410
Cdd:COG1196  622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE------- 694

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1411 qkkshnEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEkgnEFDTQLAEYQKVIDEMDDAASV 1490
Cdd:COG1196  695 ------LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE---EEELLEEEALEELPEPPDLEEL 765

                        650
                 ....*....|....*.
gi 24584806 1491 KSAlLEQLQNRVAELE 1506
Cdd:COG1196  766 ERE-LERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 391-1229 1.90e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 102.06  E-value: 1.90e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    391 REDAQNQALQLQKNINELKARIVELESALDN---------------ERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIH 455
Cdd:TIGR02168  174 RKETERKLERTRENLDRLEDILNELERQLKSlerqaekaerykelkAELRELELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    456 DLESKITKLVSATPSLQsilppDLPSDDGALQEEIAKLQEKM---TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATL 532
Cdd:TIGR02168  254 ELEELTAELQELEEKLE-----ELRLEVSELEEEIEELQKELyalANEISRLEQQKQILRERLANLERQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    533 QSelvSKDEALEKFSLSECGIEnLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVN 612
Cdd:TIGR02168  329 ES---KLDELAEELAELEEKLE-ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    613 KTDECEILQTEVRMRDEQIRELNQQLDEvtTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLN 692
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    693 DKEQLEKQISDLKQLAEQEklvrEMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQE------------- 759
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENL----EGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrlqavvvenlnaa 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    760 IKAQNTQKDFE------LVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKE------------TIIKEKEQELQQLQ 821
Cdd:TIGR02168  559 KKAIAFLKQNElgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    822 SKSAESESALKVVQVQLEQLQQQAAASGEEGSKTV------AKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAAN 895
Cdd:TIGR02168  639 KKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    896 GSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDtl 975
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE-- 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    976 haELQAERSSSSALHTKLSKFSDEIAtghkELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEE 1055
Cdd:TIGR02168  797 --ELKALREALDELRAELTLLNEEAA----NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1056 SIKNLqEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISAT-NAEL 1134
Cdd:TIGR02168  871 LESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEY 949

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1135 STVLEVLQAEKSETnhifELFEMEADMNSERLIEKVTGIK-------EELKETHLQLDERQKKFEELEEKLKQAQQSEQK 1207
Cdd:TIGR02168  950 SLTLEEAEALENKI----EDDEEEARRRLKRLENKIKELGpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025

                          890       900
                   ....*....|....*....|...
gi 24584806   1208 LQQE-SQTSKEKLTEIQQSLQEL 1229
Cdd:TIGR02168 1026 IDREaRERFKDTFDQVNENFQRV 1048
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 630-1210 7.50e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.01  E-value: 7.50e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  630 QIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAE 709
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  710 QEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKT 789
Cdd:COG1196  313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  790 LGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQ 869
Cdd:COG1196  393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  870 AEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVEskTKQLEAANAALEK 949
Cdd:COG1196  473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE--AALEAALAAALQN 550

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  950 VNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQkekELQELR 1029
Cdd:COG1196  551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT---LLGRTL 627

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1030 QQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVT-KAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQ 1108
Cdd:COG1196  628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTgGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1109 KIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKEthL------ 1182
Cdd:COG1196  708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA--Lgpvnll 785

                        570       580       590
                 ....*....|....*....|....*....|.
gi 24584806 1183 ---QLDERQKKFEELEEKLKQAQQSEQKLQQ 1210
Cdd:COG1196  786 aieEYEELEERYDFLSEQREDLEEARETLEE 816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1192-1516 1.41e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.77  E-value: 1.41e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1192 EELEEKLKQ-AQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssiIEAQNTKLNESNVQLEN 1270
Cdd:COG1196  196 GELERQLEPlERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAE----LEELEAELAELEAELEE 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1271 KTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE 1350
Cdd:COG1196  272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1351 LLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKER 1430
Cdd:COG1196  352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1431 TLQEETSKLAEQLSQLKQANEELQ-KSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETAL 1509
Cdd:COG1196  432 ELEEEEEEEEEALEEAAEEEAELEeEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511


                 ....*..
gi 24584806 1510 RQANDAQ 1516
Cdd:COG1196  512 AALLLAG 518
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 667-1540 4.32e-19

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 94.27  E-value: 4.32e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    667 EEKSTLLEKTEKELVQSKEQAAKTL-NDKEQLEKQISDLKQLA-EQEKLVREMTENAINQIQLEKESIEQQLALKQNELE 744
Cdd:pfam02463  186 AELIIDLEELKLQELKLKEQAKKALeYYQLKEKLELEEEYLLYlDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    745 DFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKeketiikeKEQELQQLQSKS 824
Cdd:pfam02463  266 KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK--------AEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    825 AESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 904
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    905 SGHLLEQITKLKSEVGETQaalsschTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERS 984
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEE-------ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    985 SSSALHTKLSKFSDEIATGHKELTSKADawsqemlqkekelqelrqqlqdsqDSQTKLKAEGERKEKSFEESIKNLQEEV 1064
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKD------------------------GVGGRIISAHGRLGDLGVAVENYKVAIS 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1065 TKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAE 1144
Cdd:pfam02463  547 TAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1145 KSETNHIFELFEMEADMNSERLIEKVTGIKEElkethLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQ 1224
Cdd:pfam02463  627 GILKDTELTKLKESAKAKESGLRKGVSLEEGL-----AEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1225 SLQELqdsvKQKEELVQNLEEKVResssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQ 1304
Cdd:pfam02463  702 KKKEQ----REKEELKKLKLEAEE-----LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLK 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1305 QVQEANGDIKDSLVKVEELvkvLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELK 1384
Cdd:pfam02463  773 EKELAEEREKTEKLKVEEE---KEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1385 EALCQKENGLKELQGKLDESNtvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL 1464
Cdd:pfam02463  850 KLAEEELERLEEEITKEELLQ--ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEA 927

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806   1465 EKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSRE 1540
Cdd:pfam02463  928 EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 370-1029 7.78e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 7.78e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    370 QDLLREKQQHVEKLmverdldrEDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQV 449
Cdd:TIGR02168  298 SRLEQQKQILRERL--------ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    450 YKEKIHDLESKITKLVSATPSLQSILppdlpsddGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENvkylneQI 529
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA------EL 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    530 ATLQSELVSKDEALEKfslsecgienlrrelellKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESE 609
Cdd:TIGR02168  436 KELQAELEELEEELEE------------------LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERL 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    610 RVNKtdecEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDML--RLQK------------------------ 663
Cdd:TIGR02168  498 QENL----EGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALggRLQAvvvenlnaakkaiaflkqnelgrv 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    664 ---EGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEK----------- 729
Cdd:TIGR02168  574 tflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRpgyrivtldgd 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    730 ------------ESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 797
Cdd:TIGR02168  654 lvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRK 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    798 ALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEgSKTVAKLHDEISQLKSQAEETQSEL 877
Cdd:TIGR02168  734 DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL-EAQIEQLKEELKALREALDELRAEL 812

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    878 KST-------QSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKV 950
Cdd:TIGR02168  813 TLLneeaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALL 892

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    951 NKEYAESRAEASDLQDKVKEitdtLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSK----ADAWSQEMLQKEKELQ 1026
Cdd:TIGR02168  893 RSELEELSEELRELESKRSE----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltLEEAEALENKIEDDEE 968


                   ...
gi 24584806   1027 ELR 1029
Cdd:TIGR02168  969 EAR 971
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
891-1513 1.60e-18

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 92.41  E-value: 1.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   891 LEAANGSLEE-----EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEkvnkEYAESRAEASDLQ 965
Cdd:PRK02224  182 LSDQRGSLDQlkaqiEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLE----EHEERREELETLE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   966 DKVKEITDTLhAELQAERSS-SSALHTK---LSKFSDEIA-----TGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ 1036
Cdd:PRK02224  258 AEIEDLRETI-AETEREREElAEEVRDLrerLEELEEERDdllaeAGLDDADAEAVEARREELEDRDEELRDRLEECRVA 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1037 DSQTKLKAEGERkeksfeESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEitnaelqhkekmasedaqKIADLKTL 1116
Cdd:PRK02224  337 AQAHNEEAESLR------EDADDLEERAEELREEAAELESELEEAREAVEDRRE------------------EIEELEEE 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1117 VEAIQVANANISATNAELSTVLEVLQAEKSETNHifELFEMEADMNSER-LIEKVTGIKEELK----------ETHLQ-L 1184
Cdd:PRK02224  393 IEELRERFGDAPVDLGNAEDFLEELREERDELRE--REAELEATLRTAReRVEEAEALLEAGKcpecgqpvegSPHVEtI 470

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1185 DERQKKFEELEEKLKQAQqseqklqqESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNEs 1264
Cdd:PRK02224  471 EEDRERVEELEAELEDLE--------EEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE- 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1265 nvqlenktsclketqdqllesqkkekqLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAt 1344
Cdd:PRK02224  542 ---------------------------LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER- 593

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1345 nkeLQELLVKSQENEGNLQgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvlesqkkshneiqDKLEQ 1424
Cdd:PRK02224  594 ---IRTLLAAIADAEDEIE----RLREKREALAELNDERRERLAEKRERKRELEAEFDE----------------ARIEE 650

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1425 AQQKERTLQEETSKLAEQLSQLKQANEELQKSLqqkqlllekgNEFDTQLAEYQKVIDEMDDAASVKSAL------LEQL 1498
Cdd:PRK02224  651 AREDKERAEEYLEQVEEKLDELREERDDLQAEI----------GAVENELEELEELRERREALENRVEALealydeAEEL 720

                         650
                  ....*....|....*
gi 24584806  1499 QNRVAELETALRQAN 1513
Cdd:PRK02224  721 ESMYGDLRAELRQRN 735
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 592-1328 5.70e-18

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 90.46  E-value: 5.70e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    592 LSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKST 671
Cdd:TIGR04523   45 IKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEV 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    672 LLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQS 751
Cdd:TIGR04523  125 ELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    752 ESEVHLQEIKAQNTQkdfeLVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAL 831
Cdd:TIGR04523  205 NLKKKIQKNKSLESQ----ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNN 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    832 KVVqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEetQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQ 911
Cdd:TIGR04523  281 KKI---------------KELEKQLNQLKSEISDLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQ 343

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    912 ITKLKSEVGETQaalsschTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQdkvkeitdtlhaelqaerSSSSALHT 991
Cdd:TIGR04523  344 ISQLKKELTNSE-------SENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE------------------SQINDLES 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    992 KLSKFSDEiatgHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEN 1071
Cdd:TIGR04523  399 KIQNQEKL----NQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLS 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1072 LElstgtqttIKDLQERLEITNAELQHKEKMASEDAQKIADLKtlvEAIQVANANISatnaELSTVLEVLQAEKSETNHI 1151
Cdd:TIGR04523  475 RS--------INKIKQNLEQKQKELKSKEKELKKLNEEKKELE---EKVKDLTKKIS----SLKEKIEKLESEKKEKESK 539

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1152 F-----ELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSL 1226
Cdd:TIGR04523  540 IsdledELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1227 QELQDSVKQKEELVQNLE---EKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQD---QLLESQKKEKQLQEEAAKLS 1300
Cdd:TIGR04523  620 EKAKKENEKLSSIIKNIKskkNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDdiiELMKDWLKELSLHYKKYITR 699

                          730       740       750
                   ....*....|....*....|....*....|..
gi 24584806   1301 ----GELQQVQEANGDIKDSLVKVEELVKVLE 1328
Cdd:TIGR04523  700 miriKDLPKLEEKYKEIEKELKKLDEFSKELE 731
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 503-1443 7.44e-18

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 90.23  E-value: 7.44e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    503 EVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEftRKL 582
Cdd:pfam01576   79 ELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE--RKL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    583 AEKSVEvlRLSSELQNLKATSDSLEseRVNKTDECEILQTEVRMRDEQ-----IRELNQQLDEVTTQLNVQKADSSALDD 657
Cdd:pfam01576  157 LEERIS--EFTSNLAEEEEKAKSLS--KLKNKHEAMISDLEERLKKEEkgrqeLEKAKRKLEGESTDLQEQIAELQAQIA 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    658 MLRLQKEGTEEK-STLLEKTEKELVQsKEQAAKTLndkEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQL 736
Cdd:pfam01576  233 ELRAQLAKKEEElQAALARLEEETAQ-KNNALKKI---RELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    737 --------------ALKQNELEDFQKKQSES----EVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEK---- 794
Cdd:pfam01576  309 edtldttaaqqelrSKREQEVTELKKALEEEtrshEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenae 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    795 LQAALEEL---KKEKETIIKEKEQELQQLQSKSAESESA---LKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKS 868
Cdd:pfam01576  389 LQAELRTLqqaKQDSEHKRKKLEGQLQELQARLSESERQraeLAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    869 QAEETQSELKS---TQSNLEAKSKQLEAANGSL----EEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLE 941
Cdd:pfam01576  469 QLQDTQELLQEetrQKLNLSTRLRQLEDERNSLqeqlEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    942 AANAALEKVNKEYAESRAEASDLQ---DKVKEITDTLHAELQAERSSSSALHTKLSKFSD------EIATGHKELTSKAD 1012
Cdd:pfam01576  549 RLQRELEALTQQLEEKAAAYDKLEktkNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQmlaeekAISARYAEERDRAE 628

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1013 AWSQE----MLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKS----------FEESIKNLQEEVTKAKTENLELSTGT 1078
Cdd:pfam01576  629 AEAREketrALSLARALEEALEAKEELERTNKQLRAEMEDLVSSkddvgknvheLERSKRALEQQVEEMKTQLEELEDEL 708

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1079 QTTiKDLQERLEIT--------NAELQHKEKMASED----AQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKS 1146
Cdd:pfam01576  709 QAT-EDAKLRLEVNmqalkaqfERDLQARDEQGEEKrrqlVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQID 787

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1147 ETNHIFElfemEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSL 1226
Cdd:pfam01576  788 AANKGRE----EAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQER 863

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1227 QELQDSV--------------KQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQL 1292
Cdd:pfam01576  864 DELADEIasgasgksalqdekRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQL 943

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1293 QEEAAKLSGELqqvQEANGDIKDslvKVEELVKVLEEKLQAATSQLDaQQATNKELQELLVKSQENEgnLQGESLAVTEK 1372
Cdd:pfam01576  944 ERQNKELKAKL---QEMEGTVKS---KFKSSIAALEAKIAQLEEQLE-QESRERQAANKLVRRTEKK--LKEVLLQVEDE 1014

                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806   1373 LQQLEQangeLKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL 1443
Cdd:pfam01576 1015 RRHADQ----YKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSKL 1081
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 863-1598 1.72e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 1.72e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    863 ISQLKSQAEETQSELKSTQSNL---EAKSKQLEAANGSLEEEAKKSghllEQITKLKSEVGETQAALSschtdveskTKQ 939
Cdd:TIGR02168  167 ISKYKERRKETERKLERTRENLdrlEDILNELERQLKSLERQAEKA----ERYKELKAELRELELALL---------VLR 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    940 LEAANAALEKVNKEYAESRAEASDLQDKVKEiTDTLHAELQAErssssalHTKLSKFSDEIATGHKELTSKAdawsQEML 1019
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQE-LEEKLEELRLE-------VSELEEEIEELQKELYALANEI----SRLE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1020 QKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEnlelstgtqttIKDLQERLEITNAELQHK 1099
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE-----------LESLEAELEELEAELEEL 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1100 EKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNS-ERLIEKVTGIKEELK 1178
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1179 ETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIE--- 1255
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSElis 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1256 -------AQNTKLNES--NVQLENktsclKETQDQLLESQKKEKQ---------LQEEAAKLSGELQQVQEANG--DIKD 1315
Cdd:TIGR02168  531 vdegyeaAIEAALGGRlqAVVVEN-----LNAAKKAIAFLKQNELgrvtflpldSIKGTEIQGNDREILKNIEGflGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1316 SLVKV-EELVKVLE---------EKLQAATSQ------------LDAQQAT---------NKELQELLVKSQENEgNLQG 1364
Cdd:TIGR02168  606 DLVKFdPKLRKALSyllggvlvvDDLDNALELakklrpgyrivtLDGDLVRpggvitggsAKTNSSILERRREIE-ELEE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1365 ESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS----HNEIQDKLEQAQQKERTLQEETSKLA 1440
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDlarlEAEVEQLEERIAQLSKELTELEAEIE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1441 EQLSQLKQANEELQKSLQQKQLLLEKGNEF-------DTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAN 1513
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAEIEELEAQIEQLkeelkalREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE 844

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1514 DAQKTAYLETKELRRQLESL-----ELEKSREVLS-LKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKN 1587
Cdd:TIGR02168  845 EQIEELSEDIESLAAEIEELeelieELESELEALLnERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKL 924

                          810
                   ....*....|.
gi 24584806   1588 DALKAKVQTLE 1598
Cdd:TIGR02168  925 AQLELRLEGLE 935
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1164-1544 4.18e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.60  E-value: 4.18e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1164 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNL 1243
Cdd:COG1196  249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1244 EEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1323
Cdd:COG1196  329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1324 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE 1403
Cdd:COG1196  409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1404 SNTVLESQkkshneiqdkleQAQQKERTLQEETSKLAEQLSQLKQANEELqkslqqkQLLLEKGNEFDTQLAEY------ 1477
Cdd:COG1196  489 AAARLLLL------------LEAEADYEGFLEGVKAALLLAGLRGLAGAV-------AVLIGVEAAYEAALEAAlaaalq 549

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806 1478 QKVIDEMDDAASVKSALLEQLQNRVAELE-TALRQANDAQKTAYLETKELRRQLESLELEKSREVLSL 1544
Cdd:COG1196  550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPlDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617
PTZ00121 PTZ00121
MAEBL; Provisional
 663-1439 8.46e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.04  E-value: 8.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   663 KEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKE-QLEKQISDLKQLAEQEKlvremTENAiNQIQLEKESIEQQLALKQN 741
Cdd:PTZ00121 1121 KKKAEDARKAEEARKAEDARKAEEARKAEDAKRvEIARKAEDARKAEEARK-----AEDA-KKAEAARKAEEVRKAEELR 1194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   742 ELEDFQK----KQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQL-----EQKTLGHEKLQAALEELKKEKETIIKE 812
Cdd:PTZ00121 1195 KAEDARKaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaeeERNNEEIRKFEEARMAHFARRQAAIKA 1274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   813 KE----QELQQLQS--KSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEA 886
Cdd:PTZ00121 1275 EEarkaDELKKAEEkkKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   887 KSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAE----AS 962
Cdd:PTZ00121 1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEekkkAD 1434

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   963 DLQDKVKEITDTLHAELQAE--RSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQT 1040
Cdd:PTZ00121 1435 EAKKKAEEAKKADEAKKKAEeaKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1041 KLKAEGERKE---KSFEESIKNLQ----EEVTKA----KTENLELSTGTQTTIKDLQERlEITNAELQHKEKMASEDAQK 1109
Cdd:PTZ00121 1515 AKKAEEAKKAdeaKKAEEAKKADEakkaEEKKKAdelkKAEELKKAEEKKKAEEAKKAE-EDKNMALRKAEEAKKAEEAR 1593

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1110 IADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADmnSERLIEKVTGIKEELKETHLQLDERQK 1189
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--EKKKAEELKKAEEENKIKAAEEAKKAE 1671

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1190 KFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEE---KVRESSSIIEAQNTKLNESNV 1266
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEEnkiKAEEAKKEAEEDKKKAEEAKK 1751

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1267 QLE--NKTSCLKETQDQLLESQKKEKQL---QEEAAKLSGELQQVQEANGDIKDSLVKVEE-------LVKVLEEKLQAA 1334
Cdd:PTZ00121 1752 DEEekKKIAHLKKEEEKKAEEIRKEKEAvieEELDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlVINDSKEMEDSA 1831

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1335 TSQLDAQQATNKELQELLVKSQENEGNLQGESlAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS 1414
Cdd:PTZ00121 1832 IKEVADSKNMQLEEADAFEKHKFNKNNENGED-GNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGK 1910

                         810       820
                  ....*....|....*....|....*.
gi 24584806  1415 HNE-IQDKLEQAQQKERTLQEETSKL 1439
Cdd:PTZ00121 1911 NNDiIDDKLDKDEYIKRDAEETREEI 1936
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1082-1590 1.87e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 1.87e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1082 IKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADM 1161
Cdd:COG1196  234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1162 NSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQ 1241
Cdd:COG1196  314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1242 NLEEKVRESSSIIEAQNTKLNESNVQLENKTSC---LKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLV 1318
Cdd:COG1196  394 AAAELAAQLEELEEAEEALLERLERLEEELEELeeaLAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1319 KVEELVKVLEEKLQAATSQLDAQQATNKELQELL--VKSQENEGNLQGESLA--------------------------VT 1370
Cdd:COG1196  474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLegVKAALLLAGLRGLAGAvavligveaayeaaleaalaaalqniVV 553

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1371 EKLQQLEQANGELKEALCQKENGL---KELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQE---ETSKLAEQLS 1444
Cdd:COG1196  554 EDDEVAAAAIEYLKAAKAGRATFLpldKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDtllGRTLVAARLE 633

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1445 QLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETK 1524
Cdd:COG1196  634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806 1525 ELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDAL 1590
Cdd:COG1196  714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 505-1325 2.44e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 82.50  E-value: 2.44e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   505 ESRIAEQLEEEQRLRENVKylneQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAE 584
Cdd:PTZ00121 1086 DNRADEATEEAFGKAEEAK----KTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   585 --KSVEVLRLSSELQNLKATSDSLE---SERVNKTDEC----------------EILQTEVRMRDEQIR---------EL 634
Cdd:PTZ00121 1162 daRKAEEARKAEDAKKAEAARKAEEvrkAEELRKAEDArkaeaarkaeeerkaeEARKAEDAKKAEAVKkaeeakkdaEE 1241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   635 NQQLDEVTTQLNVQKADSSALDDMLRLQKEG-TEEKSTLLEKTEKELVQSKEQAAKT--------LNDKEQLEKQISDLK 705
Cdd:PTZ00121 1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIkAEEARKADELKKAEEKKKADEAKKAeekkkadeAKKKAEEAKKADEAK 1321

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   706 QLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELVESGESLKKLQQ 783
Cdd:PTZ00121 1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAkkKADAAKKKAEEKKKADEAKKKAE 1401

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   784 QLEQKTLGHEKLQAA---LEELKKEKETIIKEKEQELQQLQSKSAES--ESALKVVQVQLEQLQQQAAASGEEGSKTvAK 858
Cdd:PTZ00121 1402 EDKKKADELKKAAAAkkkADEAKKKAEEKKKADEAKKKAEEAKKADEakKKAEEAKKAEEAKKKAEEAKKADEAKKK-AE 1480

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   859 LHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGsleEEAKKSGHLLEQITKLKSEvgETQAALSSCHTDVESKTK 938
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA---EEAKKADEAKKAEEAKKAD--EAKKAEEKKKADELKKAE 1555

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   939 QLEAANaalEKVNKEYAESRAEASDLQDKVKEITDTLHaelQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEM 1018
Cdd:PTZ00121 1556 ELKKAE---EKKKAEEAKKAEEDKNMALRKAEEAKKAE---EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAE 1629

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1019 LQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKnlqEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQH 1098
Cdd:PTZ00121 1630 EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK---AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE 1706

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1099 KEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELK 1178
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1179 EthlqldERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQN 1258
Cdd:PTZ00121 1787 E------EDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNEN 1860

                         810       820       830       840       850       860
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806  1259 TKLNESNVQLENKTSCLKETQDQLLESqKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1325
Cdd:PTZ00121 1861 GEDGNKEADFNKEKDLKEDDEEEIEEA-DEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIK 1926
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1006-1534 2.46e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.91  E-value: 2.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1006 ELTSKADAWSQEMLQKEK----ELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTG---T 1078
Cdd:COG1196  228 ELLLLKLRELEAELEELEaeleELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDiarL 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1079 QTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEME 1158
Cdd:COG1196  308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1159 ADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEE 1238
Cdd:COG1196  388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1239 LVQNLEEKVRESSSIIEAQNTKLNESNVQLEnktsclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQE---------- 1308
Cdd:COG1196  468 LLEEAALLEAALAELLEELAEAAARLLLLLE------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGveaayeaale 541

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1309 -------ANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKL-QQLEQAN 1380
Cdd:COG1196  542 aalaaalQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADArYYVLGDT 621

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1381 GELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEEtsKLAEQLSQLKQANEELQKSLQQK 1460
Cdd:COG1196  622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE--AEAELEELAERLAEEELELEEAL 699

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24584806 1461 QLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1534
Cdd:COG1196  700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1283-1573 2.54e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.91  E-value: 2.54e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1283 LESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK---VLEEKLQAATSQLDAQQATNKELQELLVKSQENE 1359
Cdd:COG1196  218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAelaELEAELEELRLELEELELELEEAQAEEYELLAEL 297

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1360 GNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKL 1439
Cdd:COG1196  298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1440 AEQLSQLKQANEELQKS-----------LQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETA 1508
Cdd:COG1196  378 EEELEELAEELLEALRAaaelaaqleelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806 1509 LRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKI 1573
Cdd:COG1196  458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 370-980 4.16e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.14  E-value: 4.16e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  370 QDLLREKQQHVEKLmvERDldREDAQnQALQLQKNINELKA-----RIVELESALDNERKKTEELQCSIDEAQFCGDELN 444
Cdd:COG1196  192 EDILGELERQLEPL--ERQ--AEKAE-RYRELKEELKELEAellllKLRELEAELEELEAELEELEAELEELEAELAELE 266

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  445 AQSQVYKEKIHDLESKITklvsatpslqsilppdlpsddgALQEEIAKLQEkmtiQQKEVESRIAEQLEEEQRLRENVKY 524
Cdd:COG1196  267 AELEELRLELEELELELE----------------------EAQAEEYELLA----ELARLEQDIARLEERRRELEERLEE 320

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  525 LNEQIATLQSELVSKDEALEkfslsecgienlrrelelLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSD 604
Cdd:COG1196  321 LEEELAELEEELEELEEELE------------------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  605 SLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSK 684
Cdd:COG1196  383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  685 EQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQN-----ELEDFQKKQSESEVHLQE 759
Cdd:COG1196  463 ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagAVAVLIGVEAAYEAALEA 542

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  760 IKAQNTQKDfeLVESGESLKKLQQQLEQKTLG------------HEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES 827
Cdd:COG1196  543 ALAAALQNI--VVEDDEVAAAAIEYLKAAKAGratflpldkiraRAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  828 ESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELkstQSNLEAKSKQLEAANGSLEEEAKKSGH 907
Cdd:COG1196  621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL---LAALLEAEAELEELAERLAEEELELEE 697

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806  908 LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQ 980
Cdd:COG1196  698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1280-1598 5.34e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 5.34e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1280 DQLLESQKKE-KQLQEEAAKLSGELQQVQEANG---DIKDSLVKVEELVKVLEEKLQAATSQldAQQAtnKELQELlvKS 1355
Cdd:TIGR02168  147 SEIIEAKPEErRAIFEEAAGISKYKERRKETERkleRTRENLDRLEDILNELERQLKSLERQ--AEKA--ERYKEL--KA 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1356 QENEGNLQGESLAVTEKLQQLEQANGELKEA---LCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTL 1432
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAeeeLEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1433 QEETSKLAEQLSQL----KQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETA 1508
Cdd:TIGR02168  301 EQQKQILRERLANLerqlEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1509 LRQANDAQKTAYLETKELRRQLESLELEKSRevlSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKND 1588
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLER---LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE 457

                          330
                   ....*....|
gi 24584806   1589 ALKAKVQTLE 1598
Cdd:TIGR02168  458 RLEEALEELR 467
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 570-1499 5.67e-15

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 80.86  E-value: 5.67e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    570 QAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQK 649
Cdd:TIGR00606  203 QEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQME 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    650 ADSSALDDMLRLQKEGTEEKSTLLE--------KTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENA 721
Cdd:TIGR00606  283 KDNSELELKMEKVFQGTDEQLNDLYhnhqrtvrEKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEH 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    722 INQIQLEKESIEQQLALKQNELEDFQKKQSESEVHL----QEIKAQNTQKDFELVESGESLKKlqqqlEQKTLGHEKLQA 797
Cdd:TIGR00606  363 IRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLvierQEDEAKTAAQLCADLQSKERLKQ-----EQADEIRDEKKG 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    798 ALEELKKEKETIIKEKEQ---ELQQLQSKSAESESALKVVQVQLEQLQQQAAAsgEEGSKTVAKLHDEISQLKSQAEETQ 874
Cdd:TIGR00606  438 LGRTIELKKEILEKKQEElkfVIKELQQLEGSSDRILELDQELRKAERELSKA--EKNSLTETLKKEVKSLQNEKADLDR 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    875 SELKSTQSNleAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDveskTKQLEAAnaaLEKVNKEY 954
Cdd:TIGR00606  516 KLRKLDQEM--EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPN----KKQLEDW---LHSKSKEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    955 AESRAEASDLQDKVKEITDTLHAELQAERSsssaLHTKLSKFSDEI--ATGHKELTSKADAWSQEMLQKEKELQELRQQL 1032
Cdd:TIGR00606  587 NQTRDRLAKLNKELASLEQNKNHINNELES----KEEQLSSYEDKLfdVCGSQDEESDLERLKEEIEKSSKQRAMLAGAT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1033 QDSQDSQTKLKAEgerkeksfEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIAD 1112
Cdd:TIGR00606  663 AVYSQFITQLTDE--------NQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1113 LKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfEMEADMNSERLIEKVTGIKEELKEthlQLDERQKKFE 1192
Cdd:TIGR00606  735 RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLG--TIMPEEESAKVCLTDVTIMERFQM---ELKDVERKIA 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1193 ELEEKLKQA--QQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssiieaqntklnesnvqlen 1270
Cdd:TIGR00606  810 QQAAKLQGSdlDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE--------------------- 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1271 ktscLKETQDQLLESQKKEKQLQEEAAKLSGElqqVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE 1350
Cdd:TIGR00606  869 ----LKSEKLQIGTNLQRRQQFEEQLVELSTE---VQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQD 941

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1351 LLVKSQENEGNLQGESLAVTEKLQQLEQangelkEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKER 1430
Cdd:TIGR00606  942 KVNDIKEKVKNIHGYMKDIENKIQDGKD------DYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQER 1015

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806   1431 TLQEETS--KLAEQLSQLKQANEELQKSLQQKQLLLEKgnefdtqlAEYQKVIDEMDDAASVKSALLEQLQ 1499
Cdd:TIGR00606 1016 WLQDNLTlrKRENELKEVEEELKQHLKEMGQMQVLQMK--------QEHQKLEENIDLIKRNHVLALGRQK 1078
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1016-1534 9.71e-15

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 79.68  E-value: 9.71e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1016 QEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEevTKAKTENLELS-TGTQTTIKDLQERLEITNA 1094
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYND--LKKQKEELENElNLLEKEKLNIQKNIDKIKN 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1095 ELQHKEKMASEDAQKIADLKTLVEAIqvanANISATNAELSTVLEVLQAEKSETNHIFElfemEADMNSERLIEKVTGIK 1174
Cdd:TIGR04523  195 KLLKLELLLSNLKKKIQKNKSLESQI----SELKKQNNQLKDNIEKKQQEINEKTTEIS----NTQTQLNQLKDEQNKIK 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1175 EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQtskeklteiQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1254
Cdd:TIGR04523  267 KQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKE---------QDWNKELKSELKNQEKKLEEIQNQISQNNKII 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1255 EAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAA 1334
Cdd:TIGR04523  338 SQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKL 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1335 TSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS 1414
Cdd:TIGR04523  418 QQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1415 HNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKgNEFDTQLAEYQKVIDEMDDAasvksal 1494
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKE------- 569

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 24584806   1495 LEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1534
Cdd:TIGR04523  570 IEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKE 609
PTZ00121 PTZ00121
MAEBL; Provisional
 664-1372 2.24e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.41  E-value: 2.24e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   664 EGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTE-NAINQIQLEKESIEQQLALKQNE 742
Cdd:PTZ00121 1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKaEDARKAEEARKAEDAKRVEIARK 1159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   743 LEDFQK----------KQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKEtiIKE 812
Cdd:PTZ00121 1160 AEDARKaeearkaedaKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEE--AKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   813 KEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKtvAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLE 892
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK--ADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   893 AAngslEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEIT 972
Cdd:PTZ00121 1316 KA----DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   973 DTLHAELQAERSSSSALHTK---LSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERK 1049
Cdd:PTZ00121 1392 KADEAKKKAEEDKKKADELKkaaAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1050 ---------EKSFEESIKNLQEEvTKAKTENLELSTGTQTTIKDLQERLEITNAElqhkEKMASEDAQKIADLKTLVEAI 1120
Cdd:PTZ00121 1472 adeakkkaeEAKKADEAKKKAEE-AKKKADEAKKAAEAKKKADEAKKAEEAKKAD----EAKKAEEAKKADEAKKAEEKK 1546

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1121 QVANANISATNAELSTVLEVLQAEKSETNHIFELFEME-ADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLK 1199
Cdd:PTZ00121 1547 KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEeAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK 1626

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1200 QAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKlnesnvqlenktsclKETQ 1279
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE---------------KKAA 1691

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1280 DQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAAtSQLDAQQATNKELQELLVKSQENE 1359
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA-EEAKKDEEEKKKIAHLKKEEEKKA 1770

                         730
                  ....*....|...
gi 24584806  1360 GNLQGESLAVTEK 1372
Cdd:PTZ00121 1771 EEIRKEKEAVIEE 1783
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
854-1443 4.08e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 77.80  E-value: 4.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   854 KTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKsghlLEQITKLKSEVGETQAALSSCHTDV 933
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREE----LEKLEKEVKELEELKEEIEELEKEL 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   934 ESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITdtlhaELQAERSSSSALHTKLSKFSDEIATGHKELTSkada 1013
Cdd:PRK03918  248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-----ELKEKAEEYIKLSEFYEEYLDELREIEKRLSR---- 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1014 WSQEMLQKEKELQELRQQLQDSQDSQTKLKaEGERKEKSFEESIKNLQEevTKAKTENLE-----LSTGTQTTIKDLQER 1088
Cdd:PRK03918  319 LEEEINGIEERIKELEEKEERLEELKKKLK-ELEKRLEELEERHELYEE--AKAKKEELErlkkrLTGLTPEKLEKELEE 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1089 LEITNAELQHKEK----MASEDAQKIADLKTLVEAIQVANANISATNAELS-----TVLEVLQAE-KSETNHIFELFEME 1158
Cdd:PRK03918  396 LEKAKEEIEEEISkitaRIGELKKEIKELKKAIEELKKAKGKCPVCGRELTeehrkELLEEYTAElKRIEKELKEIEEKE 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1159 ADMNSE-RLIEKVTGIKEEL---KETHLQLDERQKKFEELE-EKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSV 1233
Cdd:PRK03918  476 RKLRKElRELEKVLKKESELiklKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK 555

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1234 KQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDI 1313
Cdd:PRK03918  556 KKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1314 KDSLVKVEELVKVLEEKLQAATsqldaqQATNKELQELLVKsqenegnLQGESLAVTEKLQQLEQANGELKEALCQKENG 1393
Cdd:PRK03918  636 AETEKRLEELRKELEELEKKYS------EEEYEELREEYLE-------LSRELAGLRAELEELEKRREEIKKTLEKLKEE 702

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|..
gi 24584806  1394 LKELQGKLDESNtVLESQKKSHNEIQDKLE--QAQQKERTLQeETSKLAEQL 1443
Cdd:PRK03918  703 LEEREKAKKELE-KLEKALERVEELREKVKkyKALLKERALS-KVGEIASEI 752
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 626-1445 6.45e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 77.47  E-value: 6.45e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    626 MRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELvqskeQAAKTLNdkeqlEKQISDLK 705
Cdd:pfam15921  100 LHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL-----EAAKCLK-----EDMLEDSN 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    706 QLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNEledfqkKQSESEVHLQEIKAQNTQKDFELVESGESLK----KL 781
Cdd:pfam15921  170 TQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYE------HDSMSTMHFRSLGSAISKILRELDTEISYLKgrifPV 243

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    782 QQQLEQ-KTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLH 860
Cdd:pfam15921  244 EDQLEAlKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE 323

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    861 DEISQLKSQAEETQselKSTQSNLEAKSKQLEAANGSLEEE-------AKKSGHLLEQITKLKSEVGETQAALSSCHTDV 933
Cdd:pfam15921  324 STVSQLRSELREAK---RMYEDKIEELEKQLVLANSELTEArterdqfSQESGNLDDQLQKLLADLHKREKELSLEKEQN 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    934 ESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSdeiatghkELTSKADA 1013
Cdd:pfam15921  401 KRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS--------SLTAQLES 472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1014 wSQEMLQKEKElqelrqqlqdsqdSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLElstgtqttIKDLQERLEITN 1093
Cdd:pfam15921  473 -TKEMLRKVVE-------------ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAE--------ITKLRSRVDLKL 530

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1094 AELQHkekmasedaqkiadLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGI 1173
Cdd:pfam15921  531 QELQH--------------LKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLE 596

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1174 KE------ELKETHLQLDERQKKFEELE--------EKLKQAQQSEQKLQQESQTSKEK---LTEIQQSLQELQDSVKQK 1236
Cdd:pfam15921  597 KEindrrlELQEFKILKDKKDAKIRELEarvsdlelEKVKLVNAGSERLRAVKDIKQERdqlLNEVKTSRNELNSLSEDY 676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1237 EELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDS 1316
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEA 756

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1317 LVKVEELVKVLEEKLQAATSQLDA-QQATNKELQEL-LVKSQEN---------EGNLQGESLAVTE---KLQQLEQANGE 1382
Cdd:pfam15921  757 MTNANKEKHFLKEEKNKLSQELSTvATEKNKMAGELeVLRSQERrlkekvanmEVALDKASLQFAEcqdIIQRQEQESVR 836

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806   1383 LKealCQKENGLKELQGKLDESNTVLE-------SQKKSHNEIQDK------LEQAQQKERTLQEETSKLAEQLSQ 1445
Cdd:pfam15921  837 LK---LQHTLDVKELQGPGYTSNSSMKprllqpaSFTRTHSNVPSSqstasfLSHHSRKTNALKEDPTRDLKQLLQ 909
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 630-1534 9.80e-14

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 76.75  E-value: 9.80e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    630 QIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEK--TEKEL-VQSKEQAAKTLNDKEQLEKQISDLKQ 706
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQlqAETELcAEAEEMRARLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    707 LAEQEklvremtENAINQIQLEKESIEQQLAlkqneledfqkkqsESEVHLQEIKAQNTQKDFELVESGESLKKLQQQ-- 784
Cdd:pfam01576   83 RLEEE-------EERSQQLQNEKKKMQQHIQ--------------DLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDil 141

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    785 -LEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALkvvqVQLEQLQQQAAASGEEGSKTVAKLHDEI 863
Cdd:pfam01576  142 lLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMI----SDLEERLKKEEKGRQELEKAKRKLEGES 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    864 SQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQ---- 939
Cdd:pfam01576  218 TDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQrrdl 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    940 ---LEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQ 1016
Cdd:pfam01576  298 geeLEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEK 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1017 EMLQKEKELQELrqqlQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAEL 1096
Cdd:pfam01576  378 AKQALESENAEL----QAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAEL----AEKLSKLQSELESVSSLL 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1097 QHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELfEMEADMNSERliekvtgikeE 1176
Cdd:pfam01576  450 NEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEE-EEEAKRNVER----------Q 518

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1177 LKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTE--------------IQQSLQELQDSVKQKEELVQN 1242
Cdd:pfam01576  519 LSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEkaaaydklektknrLQQELDDLLVDLDHQRQLVSN 598

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1243 LEEKVRESSSII---EAQNTKLNESNVQLENK-----------TSCLKETQDQLLESQKKEKQLQEE----------AAK 1298
Cdd:pfam01576  599 LEKKQKKFDQMLaeeKAISARYAEERDRAEAEareketralslARALEEALEAKEELERTNKQLRAEmedlvsskddVGK 678

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1299 LSGEL--------QQVQEANG---DIKDSLVKVEELVKVLEEKLQAATSQ----LDAQQATNKELQELLVKS-------Q 1356
Cdd:pfam01576  679 NVHELerskraleQQVEEMKTqleELEDELQATEDAKLRLEVNMQALKAQferdLQARDEQGEEKRRQLVKQvreleaeL 758

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1357 ENEGNLQGESLAVTEKLQ--------QLEQANGELKEALCQkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQK 1428
Cdd:pfam01576  759 EDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQ----LKKLQAQMKDLQRELEEARASRDEILAQSKESEKK 834

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1429 ERTLQEETSKLAEQLSQLKQAN-----------EELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE-------MDDAASV 1490
Cdd:pfam01576  835 LKNLEAELLQLQEDLAASERARrqaqqerdelaDEIASGASGKSALQDEKRRLEARIAQLEEELEEeqsntelLNDRLRK 914

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|....
gi 24584806   1491 KSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1534
Cdd:pfam01576  915 STLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEME 958
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 869-1560 1.40e-13

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 76.16  E-value: 1.40e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    869 QAEETQSELKSTQSNLEAKSKQLEAANgSLEEEAKKSGHLLEQITKLKSEVGETQAALsschtDVESKTKQLEAANAALE 948
Cdd:TIGR00618  230 HLREALQQTQQSHAYLTQKREAQEEQL-KKQQLLKQLRARIEELRAQEAVLEETQERI-----NRARKAAPLAAHIKAVT 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    949 KVNKEYAESRAEasdLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKEL-TSKADAWSQEMLQKEKELQE 1027
Cdd:TIGR00618  304 QIEQQAQRIHTE---LQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDaHEVATSIREISCQQHTLTQH 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1028 LRQQLQDSQDSQTKLKAEGERKEKsfeesiknLQEEVTKAKTENLELSTGTQ------TTIKDLQERLEITNA------- 1094
Cdd:TIGR00618  381 IHTLQQQKTTLTQKLQSLCKELDI--------LQREQATIDTRTSAFRDLQGqlahakKQQELQQRYAELCAAaitctaq 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1095 ELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSE--------TNHIFELFEMEADMNS-ER 1165
Cdd:TIGR00618  453 CEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPlcgscihpNPARQDIDNPGPLTRRmQR 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1166 LIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSvkqkeelvqnLEE 1245
Cdd:TIGR00618  533 GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDL----------TEK 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1246 KVRESSSIIEAQNTKLNESNVQLENktsclketQDQLLESQKKEKQLQEEAAKLSGELQQVqeANGDIKDSLVKVEELVK 1325
Cdd:TIGR00618  603 LSEAEDMLACEQHALLRKLQPEQDL--------QDVRLHLQQCSQELALKLTALHALQLTL--TQERVREHALSIRVLPK 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1326 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1405
Cdd:TIGR00618  673 ELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1406 TvlESQKKSHNEIQDKLEQAQQKERTLQEetsklaeqLSQLKQANEELQKSLQQKQLLLEkgnefdTQLAEYQKVIDEMD 1485
Cdd:TIGR00618  753 R--TVLKARTEAHFNNNEEVTAALQTGAE--------LSHLAAEIQFFNRLREEDTHLLK------TLEAEIGQEIPSDE 816

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806   1486 DAASVKSALL----EQLQNRVAELETALRQAndaqKTAYLETKELRRQLESLeLEKSREVLSLKAQMNGASSRSGKGDE 1560
Cdd:TIGR00618  817 DILNLQCETLvqeeEQFLSRLEEKSATLGEI----THQLLKYEECSKQLAQL-TQEQAKIIQLSDKLNGINQIKIQFDG 890
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1083-1545 1.70e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 75.87  E-value: 1.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1083 KDLQERLEITNAELQHKEK--MASEDAQ-KIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEmEA 1159
Cdd:PRK03918  165 KNLGEVIKEIKRRIERLEKfiKRTENIEeLIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE-EL 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1160 DMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKlQQESQTSKEKLTEIQQSLQELQDSVKQKEEL 1239
Cdd:PRK03918  244 EKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK-AEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1240 VQNLEEKVRESSSIiEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG--------ELQQVQEANG 1311
Cdd:PRK03918  323 INGIEERIKELEEK-EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGltpeklekELEELEKAKE 401

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1312 DIKDSLVKVEELVKVLEEK---LQAATSQLDAQQAT----NKELQEllvksqENEGNLQGEslaVTEKLQQLEQANGELK 1384
Cdd:PRK03918  402 EIEEEISKITARIGELKKEikeLKKAIEELKKAKGKcpvcGRELTE------EHRKELLEE---YTAELKRIEKELKEIE 472

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1385 EALCQKENGLKELQGKLDESNTV------------LESQKKSHNeiQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEE 1452
Cdd:PRK03918  473 EKERKLRKELRELEKVLKKESELiklkelaeqlkeLEEKLKKYN--LEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1453 LQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAAsvksalLEQLQNRVAELETALRQANDAQKTAY-LETKELRRQLE 1531
Cdd:PRK03918  551 LEELKKKLAELEKKLDELEEELAELLKELEELGFES------VEELEERLKELEPFYNEYLELKDAEKeLEREEKELKKL 624

                         490
                  ....*....|....
gi 24584806  1532 SLELEKSREVLSLK 1545
Cdd:PRK03918  625 EEELDKAFEELAET 638
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
655-1249 2.51e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 75.49  E-value: 2.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   655 LDDMLRLQKEGTEEKSTLLEKTE------KELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLE 728
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTEnieeliKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKE 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   729 KESIEQQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELkkek 806
Cdd:PRK03918  247 LESLEGSKRKLEEKIRELEERIEELKKEIEELeeKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEE---- 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   807 etiIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQaaasgeegsKTVAKLHDEISQLKSQAEETQSELKS-TQSNLE 885
Cdd:PRK03918  323 ---INGIEERIKELEEKEERLEELKKKLKELEKRLEEL---------EERHELYEEAKAKKEELERLKKRLTGlTPEKLE 390

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   886 AKSKQLEAANGSLEEEAKKsghLLEQITKLKSEVGETQAALSS-------CHT-----DVESKTKQLEAANAALEKVNKE 953
Cdd:PRK03918  391 KELEELEKAKEEIEEEISK---ITARIGELKKEIKELKKAIEElkkakgkCPVcgrelTEEHRKELLEEYTAELKRIEKE 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   954 YAESRAEASDLQDKVKEITDTLHAELQAerssssalhTKLSKFSDEIatghKELTSKADAWSQEML-QKEKELQELRQQL 1032
Cdd:PRK03918  468 LKEIEEKERKLRKELRELEKVLKKESEL---------IKLKELAEQL----KELEEKLKKYNLEELeKKAEEYEKLKEKL 534

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1033 QDSQDSQTKLKAEGERKE------KSFEESIKNLQEEVTKAKTENLELSTGtqtTIKDLQERLEitNAELQHKEKMASED 1106
Cdd:PRK03918  535 IKLKGEIKSLKKELEKLEelkkklAELEKKLDELEEELAELLKELEELGFE---SVEELEERLK--ELEPFYNEYLELKD 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1107 AQKiaDLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFemeadmnSERLIEKVTGIKEELKETHLQLDE 1186
Cdd:PRK03918  610 AEK--ELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY-------SEEEYEELREEYLELSRELAGLRA 680

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806  1187 RqkkFEELEEKLKQAQQSEQKLqqesqtsKEKLTEIQQSLQELQDSVKQKEElVQNLEEKVRE 1249
Cdd:PRK03918  681 E---LEELEKRREEIKKTLEKL-------KEELEEREKAKKELEKLEKALER-VEELREKVKK 732
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
654-1244 3.10e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 75.08  E-value: 3.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   654 ALDDMLRLQKEGTEE-KSTLLEKTEKELVqskeqaaKTLNDKEQLEKQI-SDLKQLAEQEKLVREMTENAINQIQLEKES 731
Cdd:PRK02224  177 GVERVLSDQRGSLDQlKAQIEEKEEKDLH-------ERLNGLESELAELdEEIERYEEQREQARETRDEADEVLEEHEER 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   732 IEQQLALKQnELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIK 811
Cdd:PRK02224  250 REELETLEA-EIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   812 EKEQELQQLQSKSAESESALKVVQVQLEQLqqqaaasgeegsktvAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQL 891
Cdd:PRK02224  329 RLEECRVAAQAHNEEAESLREDADDLEERA---------------EELREEAAELESELEEAREAVEDRREEIEELEEEI 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   892 EAANGS-------LEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDL 964
Cdd:PRK02224  394 EELRERfgdapvdLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEED 473

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   965 QDKVKEITDTLhAELQAERSSSSALHTKLSKFSdEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKA 1044
Cdd:PRK02224  474 RERVEELEAEL-EDLEEEVEEVEERLERAEDLV-EAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEA 551

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1045 EGERKEKSFEESIKNLQEevtkaktenlelstgTQTTIKDLQERLEITNAELQHKEKMASEDAqKIADLKTLVEAIQVAN 1124
Cdd:PRK02224  552 EAEEKREAAAEAEEEAEE---------------AREEVAELNSKLAELKERIESLERIRTLLA-AIADAEDEIERLREKR 615

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1125 ANISATNAELSTVLevlqAEKSETNHifelfEMEADMNSERLiekvtgikEELKETHLQLDERQkkfEELEEKLKQAQQS 1204
Cdd:PRK02224  616 EALAELNDERRERL----AEKRERKR-----ELEAEFDEARI--------EEAREDKERAEEYL---EQVEEKLDELREE 675

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 24584806  1205 EQKLQQESQTSKEKLTEiqqsLQELQDSVKQKEELVQNLE 1244
Cdd:PRK02224  676 RDDLQAEIGAVENELEE----LEELRERREALENRVEALE 711
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 398-1301 3.44e-13

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 75.01  E-value: 3.44e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    398 ALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDEL-NAQSQVYKEKIHDLESKITKLVSATPSLQSIL- 475
Cdd:pfam02463  182 TENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLyLDYLKLNEERIDLLQELLRDEQEEIESSKQEIe 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    476 -PPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIE 554
Cdd:pfam02463  262 kEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    555 NLRRELELLKEENEKQAQEAQAEftrklaeksvevLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIREL 634
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKL------------QEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    635 NQQLdevttqLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLV 714
Cdd:pfam02463  410 LLEL------ARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    715 REMTEnainQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKT----- 789
Cdd:pfam02463  484 EQLEL----LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSatade 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    790 -LGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES-------ESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHD 861
Cdd:pfam02463  560 vEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidpilnlAQLDKATLEADEDDKRAKVVEGILKDTELTKLKE 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    862 EISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSScHTDVESKTKQLE 941
Cdd:pfam02463  640 SAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ-REKEELKKLKLE 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    942 AANAALEKVNKEYAESRAEASDLQDKVKEITDTlhaELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQK 1021
Cdd:pfam02463  719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEK 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1022 EKELQELRQQLQDsqdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEK 1101
Cdd:pfam02463  796 LKAQEEELRALEE------ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1102 MASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfemeadmnsERLIEKVTGIKEELKETH 1181
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEE----------RIKEEAEILLKYEEEPEE 939

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1182 LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKL 1261
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 24584806   1262 NESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG 1301
Cdd:pfam02463 1020 KEFLELFVSINKGWNKVFFYLELGGSAELRLEDPDDPFSG 1059
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 364-1024 5.26e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 74.38  E-value: 5.26e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    364 KSQFSMQDLLREKQQHVEKLMVERD----LDREDAQNQA---LQLQKNINELKARIVELESALDNERKKTEELQ------ 430
Cdd:pfam15921  103 KQKFYLRQSVIDLQTKLQEMQMERDamadIRRRESQSQEdlrNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRkmmlsh 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    431 ---------CSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTI-- 499
Cdd:pfam15921  183 egvlqeirsILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELll 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    500 --QQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSEL-VSKDEALEKFSLSECGIENLRRELELLKEenekQAQEAQA 576
Cdd:pfam15921  263 qqHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLeIIQEQARNQNSMYMRQLSDLESTVSQLRS----ELREAKR 338

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    577 EFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQI---RELNQQL-----------DEVT 642
Cdd:pfam15921  339 MYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELsleKEQNKRLwdrdtgnsitiDHLR 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    643 TQLNVQKADSSALDDMLRLQKE----GTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLK----QLAEQEKLV 714
Cdd:pfam15921  419 RELDDRNMEVQRLEALLKAMKSecqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTakkmTLESSERTV 498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    715 REMT------ENAINQIQLEKESIEQQLALKQNELEDFQKKQSesevHLQEIKAQNTQKDFELVESGESLKKLQQQLEQK 788
Cdd:pfam15921  499 SDLTaslqekERAIEATNAEITKLRSRVDLKLQELQHLKNEGD----HLRNVQTECEALKLQMAEKDKVIEILRQQIENM 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    789 TL---GHEKLQAALEELKKEKETIIKEKEQELQQ---LQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDE 862
Cdd:pfam15921  575 TQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQE 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    863 ISQLKSQAEETQSELKS-------TQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQI-TKLKSEVGETQAALS---SCHT 931
Cdd:pfam15921  655 RDQLLNEVKTSRNELNSlsedyevLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTrNTLKSMEGSDGHAMKvamGMQK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    932 DVESKTKQLEAANA-------ALEKVNKEYAESRAEASDLQDKVKEIT---DTLHAELQAERSSSSALHTKLSKFsdEIA 1001
Cdd:pfam15921  735 QITAKRGQIDALQSkiqfleeAMTNANKEKHFLKEEKNKLSQELSTVAtekNKMAGELEVLRSQERRLKEKVANM--EVA 812

                          730       740
                   ....*....|....*....|...
gi 24584806   1002 TGHKELTSkadAWSQEMLQKEKE 1024
Cdd:pfam15921  813 LDKASLQF---AECQDIIQRQEQ 832
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
385-970 1.35e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 73.17  E-value: 1.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   385 VERDLDREDAQNQALQLQKNINELKARIVELESALdnerKKTEELQCSIDEAqfcGDELNAQSQVYKE---KIHDLESKI 461
Cdd:PRK03918  151 VRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFI----KRTENIEELIKEK---EKELEEVLREINEissELPELREEL 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   462 TKLVSATPSLQSI--LPPDLPSDDGALQEEIAKLQEKMtiqqKEVESRIAEQLEEEQRLRENVKYLNEqiatlQSELVSK 539
Cdd:PRK03918  224 EKLEKEVKELEELkeEIEELEKELESLEGSKRKLEEKI----RELEERIEELKKEIEELEEKVKELKE-----LKEKAEE 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   540 DEALEKFslsecgienlrrelellkeenekqaqeaQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLEServnktdecei 619
Cdd:PRK03918  295 YIKLSEF----------------------------YEEYLDELREIEKRLSRLEEEINGIEERIKELEE----------- 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   620 lqtevrmRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTL----LEKTEKELVQSKEQAAKTLNDKE 695
Cdd:PRK03918  336 -------KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLtgltPEKLEKELEELEKAKEEIEEEIS 408

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   696 QLEKQISDLKQLAEQEKLV---------------REMTE----NAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVH 756
Cdd:PRK03918  409 KITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKV 488

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   757 LQEIKAQNTQKDF--ELVESGESLKKLQ-QQLEQKTLGHEKLQAALEELKKEKETIIKEKEqELQQLQSKSAESESALKV 833
Cdd:PRK03918  489 LKKESELIKLKELaeQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLDE 567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   834 VQVQLEQLQQQAaasGEEGSKTVAKLHDEISQLKSQAEEtQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQIT 913
Cdd:PRK03918  568 LEEELAELLKEL---EELGFESVEELEERLKELEPFYNE-YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE 643

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806   914 KLKSEVGETQAALS-SCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKE 970
Cdd:PRK03918  644 ELRKELEELEKKYSeEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701
PRK11281 PRK11281
mechanosensitive channel MscK;
1173-1549 1.79e-12

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 72.64  E-value: 1.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1173 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQesqtskeklteIQQSLQELQDSvkQKEELVQNLeekvrESSS 1252
Cdd:PRK11281   61 VQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQ-----------AQAELEALKDD--NDEETRETL-----STLS 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1253 IIEAQNtKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQeeaAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQ 1332
Cdd:PRK11281  123 LRQLES-RLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQ---AALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQ 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1333 AATSQLDAQQ-------ATNKELQELLvKSQENEgnlqgeslaVTEKLQQLEQANGELKEALCQKEngLKELQGKLDESN 1405
Cdd:PRK11281  199 AEQALLNAQNdlqrkslEGNTQLQDLL-QKQRDY---------LTARIQRLEHQLQLLQEAINSKR--LTLSEKTVQEAQ 266

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1406 TVLESQKKSHNE-IQDKLEQAQQKERTLQEETSKLAE----------QLSQLKQAN---EE----LQKSL-------QQK 1460
Cdd:PRK11281  267 SQDEAARIQANPlVAQELEINLQLSQRLLKATEKLNTltqqnlrvknWLDRLTQSErniKEqisvLKGSLllsrilyQQQ 346

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1461 QLL--LEKGNEFDTQLAE---YQKVIDEMDDAasvksalLEQLQNRVAELEtalrqANDAQKtaylETKELRRQLESLeL 1535
Cdd:PRK11281  347 QALpsADLIEGLADRIADlrlEQFEINQQRDA-------LFQPDAYIDKLE-----AGHKSE----VTDEVRDALLQL-L 409

                         410
                  ....*....|....*....
gi 24584806  1536 EKSREVL-----SLKAQMN 1549
Cdd:PRK11281  410 DERRELLdqlnkQLNNQLN 428
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 368-1093 1.81e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 72.36  E-value: 1.81e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    368 SMQDLLREKQQHVEKLMVERDLDREDAQNqalqLQKNINELKARIVELESALDNERKKTEELQCSIdeaqfcgDELNAQS 447
Cdd:TIGR04523   44 TIKNELKNKEKELKNLDKNLNKDEEKINN----SNNKIKILEQQIKDLNDKLKKNKDKINKLNSDL-------SKINSEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    448 QVYKEKIHDLESKITKLvsatpslqsilppdlpsddgalqeeiaklqEKmtiQQKEVESRIAEQLEEEQRLRENVKYLNE 527
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKL------------------------------EK---QKKENKKNIDKFLTEIKKKEKELEKLNN 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    528 QIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKqaqeaqaeFTRKLAEKSVEVLRLSSELQNLKATSDSLE 607
Cdd:TIGR04523  160 KYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLEL--------LLSNLKKKIQKNKSLESQISELKKQNNQLK 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    608 SERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLN-----VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQ 682
Cdd:TIGR04523  232 DNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSekqkeLEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKE 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    683 SKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKkqsESEVHLQEIKA 762
Cdd:TIGR04523  312 LKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK---ENQSYKQEIKN 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    763 QNTQKdfelvesgeslKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEkEQELQQLQSKSAESESALKVVQVQLEqlq 842
Cdd:TIGR04523  389 LESQI-----------NDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE-IERLKETIIKNNSEIKDLTNQDSVKE--- 453

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    843 qqaaasgeegsKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVG-- 920
Cdd:TIGR04523  454 -----------LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISsl 522

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    921 -ETQAALSSCHTDVESKTKQLEAanaalEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDE 999
Cdd:TIGR04523  523 kEKIEKLESEKKEKESKISDLED-----ELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKE 597

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1000 IatghKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAegerKEKSFEESIKNLQEEVTKAKTENLELSTGTQ 1079
Cdd:TIGR04523  598 K----KDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKS----KKNKLKQEVKQIKETIKEIRNKWPEIIKKIK 669

                          730
                   ....*....|....
gi 24584806   1080 TTIKDLQERLEITN 1093
Cdd:TIGR04523  670 ESKTKIDDIIELMK 683
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1016-1580 3.49e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 71.63  E-value: 3.49e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1016 QEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEEsIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAE 1095
Cdd:PRK03918  200 KELEEVLREINEISSELPELREELEKLEKEVKELEELKEE-IEELEKELESLEGSKRKL----EEKIRELEERIEELKKE 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1096 LQHKEKMASE------DAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNhifelfemeadmNSERLIEK 1169
Cdd:PRK03918  275 IEELEEKVKElkelkeKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE------------EKEERLEE 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1170 VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESqtskekLTEIQQSLQELQDSVKQKEELVQNLEEKVRE 1249
Cdd:PRK03918  343 LKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT------PEKLEKELEELEKAKEEIEEEISKITARIGE 416

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1250 SSSIIEAQNTKLNESNVQ-------------------LENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAN 1310
Cdd:PRK03918  417 LKKEIKELKKAIEELKKAkgkcpvcgrelteehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1311 gdikdSLVKVEELVKVLEEKLQAAtsQLDAQQATNKELQELLVKSQENEGNLQGESLAVtEKLQQLEQANGELKEALCQK 1390
Cdd:PRK03918  497 -----KLKELAEQLKELEEKLKKY--NLEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDEL 568

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1391 ENGLKELQGKLDE----SNTVLESQ--------------KKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEE 1452
Cdd:PRK03918  569 EEELAELLKELEElgfeSVEELEERlkelepfyneylelKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE 648

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1453 LQkslqqkqlllEKGNEFDTQlaEYQKVIDEMddaasvksallEQLQNRVAELETALRQANDAQKTAYLETKELRRQLES 1532
Cdd:PRK03918  649 LE----------ELEKKYSEE--EYEELREEY-----------LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 24584806  1533 LElEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSII 1580
Cdd:PRK03918  706 RE-KAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEI 752
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 623-985 3.93e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.64  E-value: 3.93e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    623 EVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAaktlndkEQLEKQIS 702
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERL-------EELEEDLS 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    703 DLKQlaEQEKLVREMTENAinqiqLEKESIEQQLALKQNELEDFQKKQSESEVhlQEIKAQNTQKDFELVESGESLKKLQ 782
Cdd:TIGR02169  748 SLEQ--EIENVKSELKELE-----ARIEELEEDLHKLEEALNDLEARLSHSRI--PEIQAELSKLEEEVSRIEARLREIE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    783 QQLEQKTLGHEKLQAALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKL 859
Cdd:TIGR02169  819 QKLNRLTLEKEYLEKEIQELQEQRIDLkeqIKSIEKEIENLNGKKEELEEEL------------------EELEAALRDL 880

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    860 HDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHT--DVESKT 937
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSleDVQAEL 960

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 24584806    938 KQLEAANAALEKVN----KEYAESRAEASDLQDKvkeitdtlHAELQAERSS 985
Cdd:TIGR02169  961 QRVEEEIRALEPVNmlaiQEYEEVLKRLDELKEK--------RAKLEEERKA 1004
mukB PRK04863
chromosome partition protein MukB;
1165-1539 4.92e-12

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 71.53  E-value: 4.92e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1165 RLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQElqdsvkqkeelvQNLE 1244
Cdd:PRK04863  283 VHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQ------------QEKI 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1245 EKVRESssiieaqntkLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAngdikdslvkveelv 1324
Cdd:PRK04863  351 ERYQAD----------LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQA--------------- 405

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1325 kvleeklqaatsqLDAQQATNKELQELLVKSQENEGNLQGESLAVT---EKLQQLEQANGELKEALCQKENGLKELQGKL 1401
Cdd:PRK04863  406 -------------LDVQQTRAIQYQQAVQALERAKQLCGLPDLTADnaeDWLEEFQAKEQEATEELLSLEQKLSVAQAAH 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1402 DESNTVLESQKKSHNEI--QDKLEQAQQKERTLQEEtSKLAEQLSQLKQANEELQKSLQQKQLLLEkgnefdtQLAEYQK 1479
Cdd:PRK04863  473 SQFEQAYQLVRKIAGEVsrSEAWDVARELLRRLREQ-RHLAEQLQQLRMRLSELEQRLRQQQRAER-------LLAEFCK 544

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1480 VIDEMDDAAsvksALLEQLQnrvAELETALRQANDAQKTAYLETKELRRQLESLELEKSR 1539
Cdd:PRK04863  545 RLGKNLDDE----DELEQLQ---EELEARLESLSESVSEARERRMALRQQLEQLQARIQR 597
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 806-1536 4.97e-12

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 71.36  E-value: 4.97e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    806 KETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQqqaaasgEEGSKTVAKLHDEiSQLKSQAEETQSELKSTQSNLE 885
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLC-------EEKNALQEQLQAE-TELCAEAEEMRARLAARKQELE 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    886 AKSKQLEAangSLEEEAKKSGHLL-------EQITKLKSEVGETQAALSSCHTD---VESKTKQLEAANAALEKVNKEYA 955
Cdd:pfam01576   75 EILHELES---RLEEEEERSQQLQnekkkmqQHIQDLEEQLDEEEAARQKLQLEkvtTEAKIKKLEEDILLLEDQNSKLS 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    956 EsraEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAwSQEMLQKEKELQELRQQLQDS 1035
Cdd:pfam01576  152 K---ERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQEL-EKAKRKLEGESTDLQEQIAEL 227

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1036 QDSQTKLKAEGERKEKSFEESIKNLQEEvTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKT 1115
Cdd:pfam01576  228 QAQIAELRAQLAKKEEELQAALARLEEE-TAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKT 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1116 LVEAIQvanaNISATNAELSTVLEvlqaekSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLdERQKKFEELE 1195
Cdd:pfam01576  307 ELEDTL----DTTAAQQELRSKRE------QEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQL-EQAKRNKANL 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1196 EKLKQAQQSEQK--------LQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQ 1267
Cdd:pfam01576  376 EKAKQALESENAelqaelrtLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGK 455

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1268 LENKTSCLKETQDQLLESQKkekQLQEEAA---KLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAT 1344
Cdd:pfam01576  456 NIKLSKDVSSLESQLQDTQE---LLQEETRqklNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKK 532

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1345 NKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELkealcqkENGLKELQGKLDESNTVLESQKkshnEIQDKLEQ 1424
Cdd:pfam01576  533 LEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKL-------EKTKNRLQQELDDLLVDLDHQR----QLVSNLEK 601

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1425 AQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKgnefdtQLAEYQKVIDEMDDAASVKSALLEQLQNRVAE 1504
Cdd:pfam01576  602 KQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLAR------ALEEALEAKEELERTNKQLRAEMEDLVSSKDD 675

                          730       740       750
                   ....*....|....*....|....*....|..
gi 24584806   1505 LETALRQANDAQKTAYLETKELRRQLESLELE 1536
Cdd:pfam01576  676 VGKNVHELERSKRALEQQVEEMKTQLEELEDE 707
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 729-1461 8.29e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.53  E-value: 8.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    729 KESIEQQLALKQNELEDFQKKQSES-EVH-----------------LQEIKAQ-NTQKDFELVESgESLKKLQQQLEQKT 789
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESnELHekqkfylrqsvidlqtkLQEMQMErDAMADIRRRES-QSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    790 LGHEKLQAALEELKKEKETIIKE-------KEQELQQLQSKSAESESAL-KVVQVQLEQLQQQAAASGEEGSKTVAKLHD 861
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQlrkmmlsHEGVLQEIRSILVDFEEASgKKIYEHDSMSTMHFRSLGSAISKILRELDT 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    862 EISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAkKSGHLLEqITKLKSEVGETQAALSSCHTDVESKTKQLE 941
Cdd:pfam15921  232 EISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-ISEHEVE-ITGLTEKASSARSQANSIQSQLEIIQEQAR 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    942 AANAAL--------EKVNKEYAESRAEASDLQDKVKEITDTL---HAELQAERS-------SSSALHTKLSKFSDEIATG 1003
Cdd:pfam15921  310 NQNSMYmrqlsdleSTVSQLRSELREAKRMYEDKIEELEKQLvlaNSELTEARTerdqfsqESGNLDDQLQKLLADLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1004 HKELTSKADA----WSQEM---LQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQeevtkAKTENLELST 1076
Cdd:pfam15921  390 EKELSLEKEQnkrlWDRDTgnsITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ-----GKNESLEKVS 464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1077 GTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVE----AIQVANANISATNAELSTVLEVLQAEKSETNHIf 1152
Cdd:pfam15921  465 SLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQekerAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL- 543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1153 elfemeadmnserliekvTGIKEELKETHLQLDERQKKFEELEEKLKQAQQ-------SEQKLQQESQTSKEKLTEIQQS 1225
Cdd:pfam15921  544 ------------------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrTAGAMQVEKAQLEKEINDRRLE 605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1226 LQELQDSVKQKEELVQNLEEKVressSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQlqeEAAKLSGELQQ 1305
Cdd:pfam15921  606 LQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRN---ELNSLSEDYEV 678

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1306 VQEangDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQ-------ELLVKSQENEGNLQGESLAVTEKLQQLEQ 1378
Cdd:pfam15921  679 LKR---NFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdghamKVAMGMQKQITAKRGQIDALQSKIQFLEE 755

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1379 ANGELKealcQKENGLKELQGKLDESNTVLESQKkshNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQ 1458
Cdd:pfam15921  756 AMTNAN----KEKHFLKEEKNKLSQELSTVATEK---NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828


                   ...
gi 24584806   1459 QKQ 1461
Cdd:pfam15921  829 RQE 831
PTZ00121 PTZ00121
MAEBL; Provisional
 938-1556 8.91e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 70.56  E-value: 8.91e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   938 KQLEAANAAlEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIAT--GHKELTSKAD-AW 1014
Cdd:PTZ00121 1200 RKAEAARKA-EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAhfARRQAAIKAEeAR 1278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1015 SQEMLQKEKELQ---ELRQQLQDSQDSQTKLKAEGERKE---KSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQER 1088
Cdd:PTZ00121 1279 KADELKKAEEKKkadEAKKAEEKKKADEAKKKAEEAKKAdeaKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADE 1358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1089 LEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAE---------KSETNHIFELFEMEA 1159
Cdd:PTZ00121 1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAaakkkadeaKKKAEEKKKADEAKK 1438

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1160 DMNSERLIEKVTGIKEELK--ETHLQLDERQKKFEELEEKLKQAQQSEQkLQQESQTSKEKLTEIQQSLQELQ--DSVKQ 1235
Cdd:PTZ00121 1439 KAEEAKKADEAKKKAEEAKkaEEAKKKAEEAKKADEAKKKAEEAKKADE-AKKKAEEAKKKADEAKKAAEAKKkaDEAKK 1517

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1236 KEELVQNLE-EKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIK 1314
Cdd:PTZ00121 1518 AEEAKKADEaKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1315 DSLVKVEELVKVlEEKLQAATSQLDAQQATNKELQEllvKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKEngl 1394
Cdd:PTZ00121 1598 MKLYEEEKKMKA-EEAKKAEEAKIKAEELKKAEEEK---KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA--- 1670

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1395 KELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKE--RTLQEETSKLAEQL-----------SQLKQANEELQKSLQQKQ 1461
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelKKKEAEEKKKAEELkkaeeenkikaEEAKKEAEEDKKKAEEAK 1750

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1462 LLLEKGNEFDTQLAEYQKVIDEM--DDAASVKSALLEQLQNRVAELETALRQA------------------NDAQKTAYL 1521
Cdd:PTZ00121 1751 KDEEEKKKIAHLKKEEEKKAEEIrkEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnfaniieggkegnlviNDSKEMEDS 1830

                         650       660       670
                  ....*....|....*....|....*....|....*
gi 24584806  1522 ETKELRRQlESLELEKSREVLSLKAQMNGASSRSG 1556
Cdd:PTZ00121 1831 AIKEVADS-KNMQLEEADAFEKHKFNKNNENGEDG 1864
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1132-1593 1.01e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.07  E-value: 1.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1132 AELSTVLEVLQAEKSETNHIFELFEMEADMNSERLiEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQE 1211
Cdd:PRK02224  202 KDLHERLNGLESELAELDEEIERYEEQREQARETR-DEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1212 SQTSKEKLTEIQQSLQEL----------QDSVKQKEELVQNLEEKVRESssiIEAQNTKLNESNVQLENktscLKETQDQ 1281
Cdd:PRK02224  281 VRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDR---LEECRVAAQAHNEEAES----LREDADD 353

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1282 LlESQKKEkqLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQEllvksqenegn 1361
Cdd:PRK02224  354 L-EERAEE--LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELRE----------- 419

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1362 lqgESLAVTEKLQQLEqanGELKEAlcqkENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAE 1441
Cdd:PRK02224  420 ---ERDELREREAELE---ATLRTA----RERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEE 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1442 QLSQLKQ---ANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAAsvksallEQLQNRVAELETALRQANDAQKT 1518
Cdd:PRK02224  490 EVEEVEErleRAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERA-------EELRERAAELEAEAEEKREAAAE 562

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806  1519 AYLETKELRRQLESLEleksrevlslkaqmngaSSRSGKGDEVESLD-IETSLAKINFLNSIIADMQQKNDALKAK 1593
Cdd:PRK02224  563 AEEEAEEAREEVAELN-----------------SKLAELKERIESLErIRTLLAAIADAEDEIERLREKREALAEL 621
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1256-1516 1.30e-11

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 68.25  E-value: 1.30e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1256 AQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAAT 1335
Cdd:COG4942   17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1336 SQLDAQQatnKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEalcqkenglkelqgkldesntVLESQKKSH 1415
Cdd:COG4942   97 AELEAQK---EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKY---------------------LAPARREQA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1416 NEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLekgNEFDTQLAEYQKVIDEMDDAASVKSALL 1495
Cdd:COG4942  153 EELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLL---ARLEKELAELAAELAELQQEAEELEALI 229

                        250       260
                 ....*....|....*....|.
gi 24584806 1496 EQLQNRVAELETALRQANDAQ 1516
Cdd:COG4942  230 ARLEAEAAAAAERTPAAGFAA 250
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 237-815 1.36e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 69.33  E-value: 1.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  237 MAVGDRVIVSSGFGsrpgILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFV--------------- 301
Cdd:COG5244    4 LSVNDRVLLGDKFG----TVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIrpdddsllngnaaye 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  302 --------------PIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMR--------MNAQQRKSSTPVKPI 359
Cdd:COG5244   80 kikgglvceskgmdKDGEIKQENHEDRIHFEESKIRRLEETIEALKSTEKEEIVELRreneeldkINLSLRERISSEEPE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  360 LATPKSQFSMQDL--LREKQQHVEKLMVERDLDREDAQNQALQLQKNI--NELKARIVE--------LESALDNERKKTE 427
Cdd:COG5244  160 LNKDGSKLSYDELkeFVEESRVQVYDMVELVSDISETLNRNGSIQRSSvrECERSNIHDvlflvngiLDGVIDELNGELE 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  428 ELQ---CSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLvsATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQkeV 504
Cdd:COG5244  240 RLRrqlVSLMSSHGIEVEENSRLKATLEKFQSLELKVNTL--QEELYQNKLLKKFYQIYEPFAQAALSSQLQYLAEV--I 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  505 ESRIAEQLEeeqrlrenvkylNEQIATLQSELVSKDEALEKFSLSECgiENLRRELELLKEENEKQAQEAQAEFTRKLAE 584
Cdd:COG5244  316 ESENFGKLE------------NIEIHIILKVLSSISYALHIYTIKNT--PDHLETTLQCFVNIAPISMWLSEFLQRKFSS 381

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  585 KSVEVLrlsSELQNLKATSDSLE----------------------SERVNKTDECEILQTEVRMRdeQIRELNQQlDEVT 642
Cdd:COG5244  382 KQETAF---SICQFLEDNKDVTLilkilhpilettvpkllaflrtNSNFNDNDTLCLIGSLYEIA--RIDKLIGK-EEIS 455

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  643 TQLN----VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMT 718
Cdd:COG5244  456 KQDNrlflYPSCDITLSSILTILFSDKLEVFFQGIESLLENITIFPEQPSQQTSDSENIKENSLLSDRLNEENIRLKEVL 535

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  719 ENAINQIQLEKESieQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHE---KL 795
Cdd:COG5244  536 VQKENMLTEETKI--KIIIGRDLERKTLEENIKTLKVELNNKNNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKiylDL 613

                        650       660
                 ....*....|....*....|
gi 24584806  796 QAALEELKKEKETIIKEKEQ 815
Cdd:COG5244  614 VSEIMELRETIRRQIKEQKR 633
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 359-1064 1.67e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.71  E-value: 1.67e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    359 ILATPKSQFSMQDLLREKQQHV-EKLMVERDLDREDAQNQalQLQKNINELKARIVELESALDNERKKTEELQcsideaq 437
Cdd:TIGR02169  215 ALLKEKREYEGYELLKEKEALErQKEAIERQLASLEEELE--KLTEEISELEKRLEEIEQLLEELNKKIKDLG------- 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    438 fcGDELNAqsqvYKEKIHDLESKITKLVSATPSLQSILP------PDLPSDDGALQEEIAKLQEKMTIQQKEVES---RI 508
Cdd:TIGR02169  286 --EEEQLR----VKEKIGELEAEIASLERSIAEKERELEdaeerlAKLEAEIDKLLAEIEELEREIEEERKRRDKlteEY 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    509 AEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLA----- 583
Cdd:TIGR02169  360 AELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkinel 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    584 --EKSVEVLRLSSELQNLKATSDSLESERvnktDECEILQTEVRMRDEQIRELNQQLDEVTTQLNV---QKADSSALDDM 658
Cdd:TIGR02169  440 eeEKEDKALEIKKQEWKLEQLAADLSKYE----QELYDLKEEYDRVEKELSKLQRELAEAEAQARAseeRVRGGRAVEEV 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    659 LRLQKEGTEEKSTLLEKTEKELVQSKEQAAK------TLNDKEQLEKQIsdlkQLAEQEKLVReMTENAINQIQ-----L 727
Cdd:TIGR02169  516 LKASIQGVHGTVAQLGSVGERYATAIEVAAGnrlnnvVVEDDAVAKEAI----ELLKRRKAGR-ATFLPLNKMRderrdL 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    728 EKESIEQQLALKQNeLEDFQKK---------------QSESEVHLQEIKAQNTQKDFELVE-----SGESLKKLQQQLEQ 787
Cdd:TIGR02169  591 SILSEDGVIGFAVD-LVEFDPKyepafkyvfgdtlvvEDIEAARRLMGKYRMVTLEGELFEksgamTGGSRAPRGGILFS 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    788 KTLGHE--KLQAALEELKKEKETIIKEK---EQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEgsktVAKLHDE 862
Cdd:TIGR02169  670 RSEPAElqRLRERLEGLKRELSSLQSELrriENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER----LEELEED 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    863 ISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEE-EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLE 941
Cdd:TIGR02169  746 LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLT 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    942 AANAALEKvnkEYAESRAEASDLQDKVKEITDTLHaELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQK 1021
Cdd:TIGR02169  826 LEKEYLEK---EIQELQEQRIDLKEQIKSIEKEIE-NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLREL 901

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*.
gi 24584806   1022 EKELQELRQQLQDSQDSQTKLKAEGERKE---KSFEESIKNLQEEV 1064
Cdd:TIGR02169  902 ERKIEELEAQIEKKRKRLSELKAKLEALEeelSEIEDPKGEDEEIP 947
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1327-1554 1.94e-11

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 68.89  E-value: 1.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1327 LEEKLQAATSQLDAQQAtnkELQELlvKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNT 1406
Cdd:COG3206  180 LEEQLPELRKELEEAEA---ALEEF--RQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPD 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1407 VLESQKKShNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQlllekgnefdtqlAEYQKVIDEMDD 1486
Cdd:COG3206  255 ALPELLQS-PVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ-------------QEAQRILASLEA 320

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806 1487 AASVKSALLEQLQNRVAELETALRQANDAQKtaylETKELRRQLESLE-----LEKSREVLSLKAQMNGASSR 1554
Cdd:COG3206  321 ELEALQAREASLQAQLAQLEARLAELPELEA----ELRRLEREVEVARelyesLLQRLEEARLAEALTVGNVR 389
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
515-1070 2.34e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.94  E-value: 2.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   515 EQRLRENVKYLNEQIatlqselvskdEALEKFSLSECGIENLRRELELLKEENEKQAQeaqaEFTRKLAEKSVEVLRLSS 594
Cdd:PRK03918  164 YKNLGEVIKEIKRRI-----------ERLEKFIKRTENIEELIKEKEKELEEVLREIN----EISSELPELREELEKLEK 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   595 ELQNLKATSDSLESERVnktdECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDmLRLQKEGTEEKSTLLE 674
Cdd:PRK03918  229 EVKELEELKEEIEELEK----ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYE 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   675 KTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIE--QQLALKQNELEDFQKKQSE 752
Cdd:PRK03918  304 EYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHElyEEAKAKKEELERLKKRLTG 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   753 SEVHLQEIKAQNTQKDFELVEsgESLKKLQQQLEQKTLGHEKLQAALEELKK---------------EKETIIKEKEQEL 817
Cdd:PRK03918  384 LTPEKLEKELEELEKAKEEIE--EEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelteeHRKELLEEYTAEL 461

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   818 QQLQSKSAESESALKVVQVQLEQLQQQAaasgeEGSKTVAKLHDEISQLKSQAEETQS------ELKSTQ-SNLEAKSKQ 890
Cdd:PRK03918  462 KRIEKELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKynleelEKKAEEyEKLKEKLIK 536

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   891 LEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESK----TKQLEAANAALEKVNKEYAESRAEASDLQD 966
Cdd:PRK03918  537 LKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELER 616

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   967 KVKEITDT----------LHAELQAERSSSSALHTKLSKFSDEiatGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ 1036
Cdd:PRK03918  617 EEKELKKLeeeldkafeeLAETEKRLEELRKELEELEKKYSEE---EYEELREEYLELSRELAGLRAELEELEKRREEIK 693

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|...
gi 24584806  1037 DSQTKLKAEGERKEKSFEES---------IKNLQEEVTKAKTE 1070
Cdd:PRK03918  694 KTLEKLKEELEEREKAKKELeklekalerVEELREKVKKYKAL 736
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1279-1519 2.66e-11

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 67.48  E-value: 2.66e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1279 QDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLdaqQATNKELQELLVKSQEN 1358
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL---AALEAELAELEKEIAEL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1359 EGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK 1438
Cdd:COG4942   96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1439 LAEQLSQLKQANEELQKSLQQKQLLLekgNEFDTQLAEYQKVIDEMDDAAsvksallEQLQNRVAELETALRQANDAQKT 1518
Cdd:COG4942  176 LEALLAELEEERAALEALKAERQKLL---ARLEKELAELAAELAELQQEA-------EELEALIARLEAEAAAAAERTPA 245


                 .
gi 24584806 1519 A 1519
Cdd:COG4942  246 A 246
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 1183-1458 3.79e-11

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 67.74  E-value: 3.79e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1183 QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEK--LTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTK 1260
Cdd:pfam05667  215 ELAAAQEWEEEWNSQGLASRLTPEEYRKRKRTKLLKriAEQLRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTDTGL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1261 LNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDA 1340
Cdd:pfam05667  295 TKGSRFTHTEKLQFTNEAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEE 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1341 QQATNKELQE----------LLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQ-GKLDESNTVLE 1409
Cdd:pfam05667  375 LKEQNEELEKqykvkkktldLLPDAEENIAKLQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEAKsNKEDESQRKLE 454

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806   1410 SQKKSHNEIQDKLEQAQQKE---RTLQEE-------------TSKLAEQLSQLKQANEELQKSLQ 1458
Cdd:pfam05667  455 EIKELREKIKEVAEEAKQKEelyKQLVAEyerlpkdvsrsayTRRILEIVKNIKKQKEEITKILS 519
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1209-1449 4.53e-11

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 66.71  E-value: 4.53e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1209 QQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKK 1288
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1289 EKQLQEEAAKLSGELQQVQEANGDI----KDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLvksqenegnlqg 1364
Cdd:COG4942   99 LEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR------------ 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1365 eslavteklQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLS 1444
Cdd:COG4942  167 ---------AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237


                 ....*
gi 24584806 1445 QLKQA 1449
Cdd:COG4942  238 AAAER 242
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 859-1483 4.96e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.74  E-value: 4.96e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    859 LHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTK 938
Cdd:TIGR04523   73 SNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEK 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    939 QLEAANAALEKVNKEYAESRAE----ASDLQDKVKEITDTLHAELQAERSSSS-----ALHTKLSKFSDEIATGHKELTS 1009
Cdd:TIGR04523  153 ELEKLNNKYNDLKKQKEELENElnllEKEKLNIQKNIDKIKNKLLKLELLLSNlkkkiQKNKSLESQISELKKQNNQLKD 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1010 KADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEES---IKNLQEEVTKAKTENLEL-STGTQTTIKDL 1085
Cdd:TIGR04523  233 NIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNnkkIKELEKQLNQLKSEISDLnNQKEQDWNKEL 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1086 QERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEvlqaeksETNHIFELFEMEADMNSER 1165
Cdd:TIGR04523  313 KSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELE-------EKQNEIEKLKKENQSYKQE 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1166 lIEKVTGIKEELKethLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEe 1245
Cdd:TIGR04523  386 -IKNLESQINDLE---SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLD- 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1246 kvressSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSgelQQVQEANGDIKDSLVKVEELVK 1325
Cdd:TIGR04523  461 ------NTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELE---EKVKDLTKKISSLKEKIEKLES 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1326 VLEEKlqaatsqldAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1405
Cdd:TIGR04523  532 EKKEK---------ESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLI 602

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806   1406 tvlesqkkshNEIQDKLEQAQQKERtlqeetsklaeqlsQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1483
Cdd:TIGR04523  603 ----------KEIEEKEKKISSLEK--------------ELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 374-1272 5.69e-11

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 67.76  E-value: 5.69e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    374 REKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQcSIDEAQFCGDELNAQsqvykek 453
Cdd:TIGR00606  216 KEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIK-ALKSRKKQMEKDNSE------- 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    454 ihdLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQ---EKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIA 530
Cdd:TIGR00606  288 ---LELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQrelEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIR 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    531 TLQSELVSKD-----EALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDs 605
Cdd:TIGR00606  365 ARDSLIQSLAtrlelDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIE- 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    606 LESERVNKTDE------CEILQTEVRMRDeqIRELNQQLDEVTTQLNvqKADSSALDDMLRLQKEGTEEKSTLLEKTEKE 679
Cdd:TIGR00606  444 LKKEILEKKQEelkfviKELQQLEGSSDR--ILELDQELRKAERELS--KAEKNSLTETLKKEVKSLQNEKADLDRKLRK 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    680 LVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLE---KESIEQQLALKQNELEDFQKKQSESEVH 756
Cdd:TIGR00606  520 LDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpnKKQLEDWLHSKSKEINQTRDRLAKLNKE 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    757 LQEIKAQNTQKDFELVESGESLKKLQQQLEQkTLGHEKLQAALEELKKEketiIKEKEQELQQLQSKSAESESALKVVQV 836
Cdd:TIGR00606  600 LASLEQNKNHINNELESKEEQLSSYEDKLFD-VCGSQDEESDLERLKEE----IEKSSKQRAMLAGATAVYSQFITQLTD 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    837 QLEQLQQQAaasgEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLK 916
Cdd:TIGR00606  675 ENQSCCPVC----QRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELR 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    917 SEVGETQAALSSCHTDVESKTKQLEAANAAlEKVNKEYAESRAEASDLQDKVKEITDTLhaELQAERSSSSALHTKLSKF 996
Cdd:TIGR00606  751 NKLQKVNRDIQRLKNDIEEQETLLGTIMPE-EESAKVCLTDVTIMERFQMELKDVERKI--AQQAAKLQGSDLDRTVQQV 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    997 SDEIATGHKEL---TSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERK---EKSFEESIKNLQEEVTKAKTE 1070
Cdd:TIGR00606  828 NQEKQEKQHELdtvVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRqqfEEQLVELSTEVQSLIREIKDA 907

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1071 NLELSTGTQTTIKDLQERLEITNAELQHKEK-------MASEDAQKIADLKTLVEAIQVANAN-ISATNAELSTVLEVLQ 1142
Cdd:TIGR00606  908 KEQDSPLETFLEKDQQEKEELISSKETSNKKaqdkvndIKEKVKNIHGYMKDIENKIQDGKDDyLKQKETELNTVNAQLE 987

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1143 AEKSETNHIfelfemEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLK------------QAQQSEQKLQQ 1210
Cdd:TIGR00606  988 ECEKHQEKI------NEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKqhlkemgqmqvlQMKQEHQKLEE 1061

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806   1211 ESQTSKEKLTEIQQSLQELQDSVKQ-----KEELVQNLEEKVREssSIIEAQNTKLNESNVQLENKT 1272
Cdd:TIGR00606 1062 NIDLIKRNHVLALGRQKGYEKEIKHfkkelREPQFRDAEEKYRE--MMIVMRTTELVNKDLDIYYKT 1126
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 720-1457 7.22e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.35  E-value: 7.22e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    720 NAINQIQLEKESIEQQLALKQNELEDFQKKqsesevhlqeikaqntqkdfelvesgesLKKLQQQLEQKtlgheklqaal 799
Cdd:TIGR04523   26 NIANKQDTEEKQLEKKLKTIKNELKNKEKE----------------------------LKNLDKNLNKD----------- 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    800 EELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSktvaKLHDEISQLKSQAEETQSELKS 879
Cdd:TIGR04523   67 EEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN----KLEVELNKLEKQKKENKKNIDK 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    880 TQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALsschTDVESKTKQLEAANAALEKVNKEYAESRA 959
Cdd:TIGR04523  143 FLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI----DKIKNKLLKLELLLSNLKKKIQKNKSLES 218

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    960 EASDLQDKVKEITDTlhaeLQAERSSSSALHTKLSKFSDEIatghKELTSKADAWSQEMLQKEKELQelrqqlqdsqdsq 1039
Cdd:TIGR04523  219 QISELKKQNNQLKDN----IEKKQQEINEKTTEISNTQTQL----NQLKDEQNKIKKQLSEKQKELE------------- 277

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1040 tklkaEGERKEKSFEESIKNLQEEVTKAKTE-NLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVE 1118
Cdd:TIGR04523  278 -----QNNKKIKELEKQLNQLKSEISDLNNQkEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELT 352

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1119 AIQVANANISATNAELSTVLEVLQAEKSETNhifelfemeadmnserliEKVTGIKEELKETHLQLDERQKKFEELEEKL 1198
Cdd:TIGR04523  353 NSESENSEKQRELEEKQNEIEKLKKENQSYK------------------QEIKNLESQINDLESKIQNQEKLNQQKDEQI 414

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1199 KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEekvressSIIEAQNTKLNESNVQLENKTSCLKET 1278
Cdd:TIGR04523  415 KKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLD-------NTRESLETQLKVLSRSINKIKQNLEQK 487

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1279 QDQLLESQKKEKQLQEEAAKLSgelQQVQEANGDIKDSLVKVEELVKVLEEKlqaatsqldAQQATNKELQELLVKSQEN 1358
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKELE---EKVKDLTKKISSLKEKIEKLESEKKEK---------ESKISDLEDELNKDDFELK 555

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1359 EGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK 1438
Cdd:TIGR04523  556 KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635

                          730
                   ....*....|....*....
gi 24584806   1439 LAEQLSQLKQANEELQKSL 1457
Cdd:TIGR04523  636 IKSKKNKLKQEVKQIKETI 654
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1372-1600 9.16e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 9.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1372 KLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLS----QLK 1447
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIArleeRRR 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1448 QANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELR 1527
Cdd:COG1196  313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806 1528 RQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLETL 1600
Cdd:COG1196  393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
382-1002 1.10e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 66.60  E-value: 1.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   382 KLMVERDLDreDAQNQALQLQKNINE-----LKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHD 456
Cdd:PRK02224  175 RLGVERVLS--DQRGSLDQLKAQIEEkeekdLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   457 LESkitklvsatpslqsilppdlpsddgaLQEEIAKLQEKmtiqqkevesrIAEQLEEEQRLRENVKYLNEQIATLQSEL 536
Cdd:PRK02224  253 LET--------------------------LEAEIEDLRET-----------IAETEREREELAEEVRDLRERLEELEEER 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   537 vskDEALEKFSLSECGIEnlrrelelLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDE 616
Cdd:PRK02224  296 ---DDLLAEAGLDDADAE--------AVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREE 364

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   617 CEILQTE-------VRMRDEQIRELNQQLDEVTTQLN---VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQ 686
Cdd:PRK02224  365 AAELESEleeareaVEDRREEIEELEEEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE 444

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   687 AAKTLNdkeqlEKQISDLKQLAEQEKLVREMTENainqiqlekesiEQQLALKQNELEDFQKKQSESEvhlqeikaqntq 766
Cdd:PRK02224  445 AEALLE-----AGKCPECGQPVEGSPHVETIEED------------RERVEELEAELEDLEEEVEEVE------------ 495

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   767 kdfELVESGESLKKLQQQLEQKtlghEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvQVQLEQLQQQAA 846
Cdd:PRK02224  496 ---ERLERAEDLVEAEDRIERL----EERREDLEELIAERRETIEEKRERAEELRERAAELEAE----AEEKREAAAEAE 564

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   847 ASGEEGSKTVAKLHDEISQLKSQAE------ETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVG 920
Cdd:PRK02224  565 EEAEEAREEVAELNSKLAELKERIEslerirTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFD 644

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   921 ETQaalsschtdVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLH--AELQAERSSSSALHTKLSKFSD 998
Cdd:PRK02224  645 EAR---------IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEelEELRERREALENRVEALEALYD 715


                  ....
gi 24584806   999 EIAT 1002
Cdd:PRK02224  716 EAEE 719
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1175-1387 1.16e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 65.56  E-value: 1.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1175 EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1254
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1255 EAQNTKLNESNVQLEnKTSclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAA 1334
Cdd:COG4942  100 EAQKEELAELLRALY-RLG--RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 24584806 1335 TSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEAL 1387
Cdd:COG4942  177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1154-1465 1.16e-10

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 66.40  E-value: 1.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1154 LFEMEADMNSERLIEkvtgIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSV 1233
Cdd:PRK04778   88 LFEAEELNDKFRFRK----AKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELRKSLLANRFSF 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1234 --------KQKEELVQNLEEKVRESSS--IIEAQNT--KLNESNVQLENKT--------SCLKETQDQLLESQKKEKQLQ 1293
Cdd:PRK04778  164 gpaldeleKQLENLEEEFSQFVELTESgdYVEAREIldQLEEELAALEQIMeeipellkELQTELPDQLQELKAGYRELV 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1294 EE-----AAKLSGELQQVQEAngdIKDSLVKVEEL-VKVLEEKLQAATSQLD-----------AQQ---ATNKELQELLV 1353
Cdd:PRK04778  244 EEgyhldHLDIEKEIQDLKEQ---IDENLALLEELdLDEAEEKNEEIQERIDqlydilerevkARKyveKNSDTLPDFLE 320

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1354 KSQENEGNLQGEslavTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQ 1433
Cdd:PRK04778  321 HAKEQNKELKEE----IDRVKQSYTLNESELESVRQLEKQLESLEKQYDEITERIAEQEIAYSELQEELEEILKQLEEIE 396

                         330       340       350
                  ....*....|....*....|....*....|..
gi 24584806  1434 EETSKLAEQLSQLKQANEELQKSLQQKQLLLE 1465
Cdd:PRK04778  397 KEQEKLSEMLQGLRKDELEAREKLERYRNKLH 428
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1166-1534 1.19e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 1.19e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1166 LIEKVTGIKE--ELKETHL-QLDERQKKFEELEEKLKQAQQSEQKLQQESQTsKEKLTEIQQSLQELQDSVKQKEElvqn 1242
Cdd:TIGR02169  158 IIDEIAGVAEfdRKKEKALeELEEVEENIERLDLIIDEKRQQLERLRREREK-AERYQALLKEKREYEGYELLKEK---- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1243 leEKVRESSSIIEAQNTKLNESNVQLEnktsclKETQDQLLESQKKEKQLQEEAAKL----SGELQQVQEANGDIKDSLV 1318
Cdd:TIGR02169  233 --EALERQKEAIERQLASLEEELEKLT------EEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIA 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1319 KVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQ 1398
Cdd:TIGR02169  305 SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1399 GKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGnefDTQLAEYQ 1478
Cdd:TIGR02169  385 DELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ---EWKLEQLA 461

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806   1479 KVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1534
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLK 517
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 384-805 1.68e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.23  E-value: 1.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    384 MVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITK 463
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    464 lvsatpslqsilppdlpsddgaLQEEIAKLQEKMTiqqkEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEAL 543
Cdd:TIGR02168  752 ----------------------LSKELTELEAEIE----ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL 805

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    544 EKFS--LSECGIENLRRELELLKEENEKQAQEAQAEFTRK-LAEKSVEVLRLSSELQNLKATSDSLESERvnktdecEIL 620
Cdd:TIGR02168  806 DELRaeLTLLNEEAANLRERLESLERRIAATERRLEDLEEqIEELSEDIESLAAEIEELEELIEELESEL-------EAL 878

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    621 QTEVRMRDEQIRELNQQLDEVTTQLNvqkadsSALDDMLRLQKEgteekstlLEKTEKELVQSKEQAAKTLNDKEQLekq 700
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELR------ELESKRSELRRE--------LEELREKLAQLELRLEGLEVRIDNL--- 941

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    701 isdLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFqkkqseSEVHL---QEIKAQNTQKDFelvesges 777
Cdd:TIGR02168  942 ---QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL------GPVNLaaiEEYEELKERYDF-------- 1004

                          410       420
                   ....*....|....*....|....*...
gi 24584806    778 lkkLQQQLEQKTLGHEKLQAALEELKKE 805
Cdd:TIGR02168 1005 ---LTAQKEDLTEAKETLEEAIEEIDRE 1029
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
962-1600 1.70e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 66.22  E-value: 1.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   962 SDLQDKVKEITDT-LHAELQAERSSSSALHTKLSKFSDEIATGhKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSqt 1040
Cdd:PRK02224  190 DQLKAQIEEKEEKdLHERLNGLESELAELDEEIERYEEQREQA-RETRDEADEVLEEHEERREELETLEAEIEDLRET-- 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1041 klKAEGERKEKSFEESIKNLQEEVTKAKTEN------LELSTGTQTTIKDLQERLEITNAELQhkekmasedaqkiadlk 1114
Cdd:PRK02224  267 --IAETEREREELAEEVRDLRERLEELEEERddllaeAGLDDADAEAVEARREELEDRDEELR----------------- 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1115 tlvEAIQVANANISATNAELSTVLEvlQAEKSETNhifelfemeadmnSERLIEKVTGIKEELKETHLQLDERQKKFEEL 1194
Cdd:PRK02224  328 ---DRLEECRVAAQAHNEEAESLRE--DADDLEER-------------AEELREEAAELESELEEAREAVEDRREEIEEL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1195 EEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSC 1274
Cdd:PRK02224  390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVET 469

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1275 LKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEangdikdsLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVK 1354
Cdd:PRK02224  470 IEEDRERVEELEAELEDLEEEVEEVEERLERAED--------LVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1355 SQENEGNLQGESLAVTEKLQQLEQANGELKEALcqkenglKELQGKLDESNTVLESQkkshNEIQDKLEQAQQKERTLQE 1434
Cdd:PRK02224  542 LRERAAELEAEAEEKREAAAEAEEEAEEAREEV-------AELNSKLAELKERIESL----ERIRTLLAAIADAEDEIER 610

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1435 etskLAEQLSQLKQANEELQKSLQQKqlllekgNEFDTQLAEyqkvidEMDDAAsvksalLEQLQNRVAELETALRQAND 1514
Cdd:PRK02224  611 ----LREKREALAELNDERRERLAEK-------RERKRELEA------EFDEAR------IEEAREDKERAEEYLEQVEE 667

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1515 aqktaylETKELRRQLESLEleksrevlslkAQMNGASSrsgkgdEVESLDietslakinflnsiiaDMQQKNDALKAKV 1594
Cdd:PRK02224  668 -------KLDELREERDDLQ-----------AEIGAVEN------ELEELE----------------ELRERREALENRV 707


                  ....*.
gi 24584806  1595 QTLETL 1600
Cdd:PRK02224  708 EALEAL 713
PTZ00121 PTZ00121
MAEBL; Provisional
 422-1024 2.34e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.93  E-value: 2.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   422 ERKKTEELQCSIDEAQfCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSilPPDLPSDDGALQEEIAKLQEKMTIQQ 501
Cdd:PTZ00121 1300 EKKKADEAKKKAEEAK-KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA--EAEAAADEAEAAEEKAEAAEKKKEEA 1376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   502 KEvESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIEnlrreLELLKEENEKQAQEA-QAEFTR 580
Cdd:PTZ00121 1377 KK-KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE-----EKKKADEAKKKAEEAkKADEAK 1450

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   581 KLAE--KSVEVLRLSSElQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIR---ELNQQLDEVTTQLNVQKADSSAL 655
Cdd:PTZ00121 1451 KKAEeaKKAEEAKKKAE-EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKkaaEAKKKADEAKKAEEAKKADEAKK 1529

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   656 DDMLRLQKEG--TEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIE 733
Cdd:PTZ00121 1530 AEEAKKADEAkkAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   734 QQLalKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQqqlEQKTLGHEKLQAALEELKKEKETIIKEK 813
Cdd:PTZ00121 1610 EEA--KKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE---EENKIKAAEEAKKAEEDKKKAEEAKKAE 1684

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   814 EQELQQLQSKSAESESALKVVQVQLEQLQQQAAasGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKqleA 893
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK--AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK---I 1759

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   894 ANGSLEEEAKKSGHLLEQITKLKSEVGETQaalSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQD-KVKEIT 972
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEED---EKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDsAIKEVA 1836

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|..
gi 24584806   973 DTlhAELQAERSSSSALHtKLSKFSDEIATGHKELTSKADAWSQEMLQKEKE 1024
Cdd:PTZ00121 1837 DS--KNMQLEEADAFEKH-KFNKNNENGEDGNKEADFNKEKDLKEDDEEEIE 1885
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1188-1527 2.37e-10

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 65.24  E-value: 2.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1188 QKKFEELEE-----KLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLN 1262
Cdd:PRK04778   85 EEQLFEAEElndkfRFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELRKSLLANRFSFG 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1263 ESNVQLENKtscLKETQDQLlesqKKEKQLQEEA--AKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAatsQLDA 1340
Cdd:PRK04778  165 PALDELEKQ---LENLEEEF----SQFVELTESGdyVEAREILDQLEEELAALEQIMEEIPELLKELQTELPD---QLQE 234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1341 QQATNKELQEllvksqEN----EGNLQGESLAVTEKLQQLEQ--ANGELKEAlcqkENGLKELQGKLDESNTVLESQKKS 1414
Cdd:PRK04778  235 LKAGYRELVE------EGyhldHLDIEKEIQDLKEQIDENLAllEELDLDEA----EEKNEEIQERIDQLYDILEREVKA 304

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1415 HNEIQDKLEqaqqkerTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSAL 1494
Cdd:PRK04778  305 RKYVEKNSD-------TLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQLEKQLESLEKQYDEITERIAEQEIA 377

                         330       340       350
                  ....*....|....*....|....*....|...
gi 24584806  1495 LEQLQNRVAELETALRQANDAQKTAYLETKELR 1527
Cdd:PRK04778  378 YSELQEELEEILKQLEEIEKEQEKLSEMLQGLR 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1212-1455 5.23e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 63.24  E-value: 5.23e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1212 SQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLenktsclKETQDQLLESQKKEKQ 1291
Cdd:COG4942   15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI-------RALEQELAALEAELAE 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1292 LQEEAAKLSGELQQVQEANGDIKDSLVKVEElvkvlEEKLQAATSQLDAQQA-TNKELQELLVKSQENEGNlqgeslAVT 1370
Cdd:COG4942   88 LEKEIAELRAELEAQKEELAELLRALYRLGR-----QPPLALLLSPEDFLDAvRRLQYLKYLAPARREQAE------ELR 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1371 EKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1450
Cdd:COG4942  157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236


                 ....*
gi 24584806 1451 EELQK 1455
Cdd:COG4942  237 AAAAE 241
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1013-1591 5.43e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 64.61  E-value: 5.43e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1013 AWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEIT 1092
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1093 NAEL---QHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEK 1169
Cdd:pfam02463  243 QELLrdeQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1170 VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRE 1249
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1250 SSSIIEAQNTKLNESNVQLEN-------KTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1322
Cdd:pfam02463  403 EEKEAQLLLELARQLEDLLKEekkeeleILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1323 LVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELK-EALCQKENGLKELQGKL 1401
Cdd:pfam02463  483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAiSTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1402 DESNT-VLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAneelqKSLQQKQLLLEKGNEFDTQLAEYQKV 1480
Cdd:pfam02463  563 RQKLVrALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKA-----TLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1481 IDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVL--SLKAQMNGASSRSGKG 1558
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLeiKKKEQREKEELKKLKL 717

                          570       580       590
                   ....*....|....*....|....*....|...
gi 24584806   1559 DEVESLDIETSLAKINFLNSIIADMQQKNDALK 1591
Cdd:pfam02463  718 EAEELLADRVQEAQDKINEELKLLKQKIDEEEE 750
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 401-719 6.26e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 6.26e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    401 LQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPpDLP 480
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELK-ELE 764

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    481 SDDGALQEEIAKLQEKM-TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELvsKDEALEKFSLSEcgienlrre 559
Cdd:TIGR02169  765 ARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKL--NRLTLEKEYLEK--------- 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    560 LELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLD 639
Cdd:TIGR02169  834 EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIE 913

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    640 EVTTQLNVQKADSSALDDML----RLQKEGTEEKS-TLLEKTEKELVQSKEQAAKTL--------NDKEQLEKQISDLKq 706
Cdd:TIGR02169  914 KKRKRLSELKAKLEALEEELseieDPKGEDEEIPEeELSLEDVQAELQRVEEEIRALepvnmlaiQEYEEVLKRLDELK- 992

                          330
                   ....*....|...
gi 24584806    707 lAEQEKLVREMTE 719
Cdd:TIGR02169  993 -EKRAKLEEERKA 1004
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 1175-1511 8.65e-10

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 63.17  E-value: 8.65e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1175 EELKETHLQL----DERQKKFEELEEKLKQAQQSEQKLQ---QESQTSKEKLTEIQQS------LQELQDSVKQKEELVQ 1241
Cdd:pfam05622   69 EQLQEENFRLetarDDYRIKCEELEKEVLELQHRNEELTslaEEAQALKDEMDILRESsdkvkkLEATVETYKKKLEDLG 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1242 NLEEKVR--ESSSIIEAQNT--------KLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAng 1311
Cdd:pfam05622  149 DLRRQVKllEERNAEYMQRTlqleeelkKANALRGQLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLEALQKE-- 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1312 diKDSLVKVEELVKVLEEKLQAAtsqlDAQQATNKELQELLVKSQENEGNLQGE--SLAVTEKLQQLEQANGELKealCQ 1389
Cdd:pfam05622  227 --KERLIIERDTLRETNEELRCA----QLQQAELSQADALLSPSSDPGDNLAAEimPAEIREKLIRLQHENKMLR---LG 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1390 KEnglkelqgkldesntvlESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNE 1469
Cdd:pfam05622  298 QE-----------------GSYRERLTELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSL 360

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 24584806   1470 FDTQLAEYQKVIDEMDDAASVKSALLEQLQN--------RVAELETALRQ 1511
Cdd:pfam05622  361 LKQKLEEHLEKLHEAQSELQKKKEQIEELEPkqdsnlaqKIDELQEALRK 410
mukB PRK04863
chromosome partition protein MukB;
668-1534 1.18e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 63.44  E-value: 1.18e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   668 EKSTLLEKTEKELVQSKEQAAKTLN-------DKEQLEKQISDLK----QLAEQEKLV------REMTENAINQIQLEKE 730
Cdd:PRK04863  314 RELAELNEAESDLEQDYQAASDHLNlvqtalrQQEKIERYQADLEeleeRLEEQNEVVeeadeqQEENEARAEAAEEEVD 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   731 SIEQQLALKQNELEDFQKKQSESEvhlQEIKAqntqkdfelvesgesLKKLQQQLEQKTLGHEKLQAALEELKKEKetii 810
Cdd:PRK04863  394 ELKSQLADYQQALDVQQTRAIQYQ---QAVQA---------------LERAKQLCGLPDLTADNAEDWLEEFQAKE---- 451

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   811 KEKEQELQQLQSKSAESESALKVVqvqleqlqqqaaasgEEGSKTVAKLHDEISqlKSQAEETQSELKSTQSNLEAKSKQ 890
Cdd:PRK04863  452 QEATEELLSLEQKLSVAQAAHSQF---------------EQAYQLVRKIAGEVS--RSEAWDVARELLRRLREQRHLAEQ 514

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   891 LEAANGSLEEeAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAAnaaLEKVNKEYAESRAEASDLQDKVKE 970
Cdd:PRK04863  515 LQQLRMRLSE-LEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEAR---LESLSESVSEARERRMALRQQLEQ 590

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   971 ItDTLHAELQAERSSSSALHTKLSKFSDEiaTGHKELTSKA-DAWSQEMLQKEKELQELRQqlqdsqdsqtklkaEGERK 1049
Cdd:PRK04863  591 L-QARIQRLAARAPAWLAAQDALARLREQ--SGEEFEDSQDvTEYMQQLLERERELTVERD--------------ELAAR 653

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1050 EKSFEESIKNLQEEvtkaktenlelSTGTQTTIKDLQERLE-ITNAELQhkEKMASEDAQKI-ADLKTLVEAIQVAnani 1127
Cdd:PRK04863  654 KQALDEEIERLSQP-----------GGSEDPRLNALAERFGgVLLSEIY--DDVSLEDAPYFsALYGPARHAIVVP---- 716

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1128 satnaELSTVLEVLQAEKSETNhifELFEMEADMNSerLIEKVTGIKEELKETHLQLDERQ---KKFEEL--------EE 1196
Cdd:PRK04863  717 -----DLSDAAEQLAGLEDCPE---DLYLIEGDPDS--FDDSVFSVEELEKAVVVKIADRQwrySRFPEVplfgraarEK 786

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1197 KLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQK---------EELVQNLEEKVREsssiIEAQNTKLNESNVQ 1267
Cdd:PRK04863  787 RIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHlavafeadpEAELRQLNRRRVE----LERALADHESQEQQ 862

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1268 LENKTSCLKETQDQL--LESQKK---EKQLQEEAAKLSGELQQVQEANGDIKdslvkveelvkvleeKLQAATSQLDAQQ 1342
Cdd:PRK04863  863 QRSQLEQAKEGLSALnrLLPRLNllaDETLADRVEEIREQLDEAEEAKRFVQ---------------QHGNALAQLEPIV 927

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1343 ATnkeLQEllvkSQENEGNLQGESLAVTEKLQQLEQANGELKEaLCQKENGLK--ELQGKLDESNTVLESqkkshneIQD 1420
Cdd:PRK04863  928 SV---LQS----DPEQFEQLKQDYQQAQQTQRDAKQQAFALTE-VVQRRAHFSyeDAAEMLAKNSDLNEK-------LRQ 992

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1421 KLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQlllekgnefdTQLAEYQKVIDEMDDAASvkSALLEQLQN 1500
Cdd:PRK04863  993 RLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKR----------QMLQELKQELQDLGVPAD--SGAEERARA 1060

                         890       900       910       920
                  ....*....|....*....|....*....|....*....|..
gi 24584806  1501 RVAELETALRqANDAQKTAY--------LETKELRRQLESLE 1534
Cdd:PRK04863 1061 RRDELHARLS-ANRSRRNQLekqltfceAEMDNLTKKLRKLE 1101
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 583-1255 1.30e-09

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 63.45  E-value: 1.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    583 AEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQ 662
Cdd:TIGR00618  194 GKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    663 K-----EGTEEKSTLLEKTEK---------ELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLE 728
Cdd:TIGR00618  274 AqeavlEETQERINRARKAAPlaahikavtQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQ 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    729 KESIEQQLALKQNELEDFQKKQSESE--VHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEK 806
Cdd:TIGR00618  354 EIHIRDAHEVATSIREISCQQHTLTQhiHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQ 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    807 ETIIKEKEQELQ--QLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNL 884
Cdd:TIGR00618  434 ELQQRYAELCAAaiTCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHP 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    885 EAKSKQLeaanGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDL 964
Cdd:TIGR00618  514 NPARQDI----DNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    965 QDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELT--SKADAWSQEMLQKEKELQELRQQLQDSQDSQTK- 1041
Cdd:TIGR00618  590 QNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHlqQCSQELALKLTALHALQLTLTQERVREHALSIRv 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1042 LKAEGERKEKSFEESIKNLQEEVTKAKTE----NLELSTGTQTTIKDLQERLEITNAELQHKEKMASED---AQKIADLK 1114
Cdd:TIGR00618  670 LPKELLASRQLALQKMQSEKEQLTYWKEMlaqcQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREdalNQSLKELM 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1115 TLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEEL 1194
Cdd:TIGR00618  750 HQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQE 829

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806   1195 EEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIE 1255
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDG 890
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 695-1595 1.31e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 63.21  E-value: 1.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    695 EQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEiKAQNTQKDFELVES 774
Cdd:pfam15921   81 EEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRN-QLQNTVHELEAAKC 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    775 geslkklqqqLEQKTLGHEKLQaaLEELKKeketIIKEKEQELQQLQSKSAESESAL-KVVQVQLEQLQQQAAASGEEGS 853
Cdd:pfam15921  160 ----------LKEDMLEDSNTQ--IEQLRK----MMLSHEGVLQEIRSILVDFEEASgKKIYEHDSMSTMHFRSLGSAIS 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    854 KTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLeaangsLEEEAKKSGHLleqITKLKSEVGETQAALSSCHTDV 933
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL------LQQHQDRIEQL---ISEHEVEITGLTEKASSARSQA 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    934 ESKTKQLEAANAALEKVNKEYAEsraEASDLQDKVKEITDTLhaelqaeRSSSSALHTKLSKFSDEIATGHKELT---SK 1010
Cdd:pfam15921  295 NSIQSQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSEL-------REAKRMYEDKIEELEKQLVLANSELTearTE 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1011 ADAWSQEMLQKEKELQelrqqlqdsqdsqtKLKAEGERKEKsfeesiknlqeEVTKAKTENLEL---STGTQTTIKDLQE 1087
Cdd:pfam15921  365 RDQFSQESGNLDDQLQ--------------KLLADLHKREK-----------ELSLEKEQNKRLwdrDTGNSITIDHLRR 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1088 RLEITNAELQHKEKMasedaqkiadlktlveaiqvananisatnaelstvlevLQAEKSETNHIFELfEMEADMNSERLI 1167
Cdd:pfam15921  420 ELDDRNMEVQRLEAL--------------------------------------LKAMKSECQGQMER-QMAAIQGKNESL 460

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1168 EKVTGIKEELKETHLQLderQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKV 1247
Cdd:pfam15921  461 EKVSSLTAQLESTKEML---RKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLK 537

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1248 RESSSIIEAQnTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEangDIKDSLVKVEELvKVL 1327
Cdd:pfam15921  538 NEGDHLRNVQ-TECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEK---EINDRRLELQEF-KIL 612

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1328 EEKLQAATSQLDAqqatnkelqellvksqenegnlqgeslavteKLQQLEQANGELKEALCQKENGLKELQgklDESNTV 1407
Cdd:pfam15921  613 KDKKDAKIRELEA-------------------------------RVSDLELEKVKLVNAGSERLRAVKDIK---QERDQL 658

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1408 LESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDtqlAEYQKVIDEMDDA 1487
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSD---GHAMKVAMGMQKQ 735

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1488 ASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMngaSSRSGKGDEVESLDIE 1567
Cdd:pfam15921  736 ITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLR---SQERRLKEKVANMEVA 812

                          890       900
                   ....*....|....*....|....*...
gi 24584806   1568 TSLAKINFLNSIIADMQQKNDALKAKVQ 1595
Cdd:pfam15921  813 LDKASLQFAECQDIIQRQEQESVRLKLQ 840
PTZ00121 PTZ00121
MAEBL; Provisional
 1049-1541 1.33e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 1.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1049 KEKSFEESIKNLQEEVTKAKTENLELSTGTQTTikdlqerlEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANIS 1128
Cdd:PTZ00121 1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETG--------KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA 1148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1129 ATNAELSTVLEVLQAEKSEtnhIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEElEEKLKQAQQSEQKL 1208
Cdd:PTZ00121 1149 EDAKRVEIARKAEDARKAE---EARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEE-ERKAEEARKAEDAK 1224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1209 QQESQtskEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKK 1288
Cdd:PTZ00121 1225 KAEAV---KKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1289 EKQlqEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGE--- 1365
Cdd:PTZ00121 1302 KKA--DEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAkkk 1379

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1366 SLAVTEKLQQLEQANgELKEALCQKENGLKELQGKLDESNTVLESQKKShnEIQDKLEQAQQK--ERTLQEETSKLAEQ- 1442
Cdd:PTZ00121 1380 ADAAKKKAEEKKKAD-EAKKKAEEDKKKADELKKAAAAKKKADEAKKKA--EEKKKADEAKKKaeEAKKADEAKKKAEEa 1456

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1443 --LSQLKQANEELQKSLQQKQLLLE--KGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKT 1518
Cdd:PTZ00121 1457 kkAEEAKKKAEEAKKADEAKKKAEEakKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA 1536

                         490       500
                  ....*....|....*....|...
gi 24584806  1519 AYLETKELRRQLEslELEKSREV 1541
Cdd:PTZ00121 1537 DEAKKAEEKKKAD--ELKKAEEL 1557
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1164-1599 1.34e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.40  E-value: 1.34e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1164 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQS--------EQKLQQESQTSKEKLTEIQQSLQELQdsvkq 1235
Cdd:COG4913  291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQirgnggdrLEQLEREIERLERELEERERRRARLE----- 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1236 keELVQNLEEKVRESSSIIEAQNTKLNEsnvQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQ---------- 1305
Cdd:COG4913  366 --ALLAALGLPLPASAEEFAALRAEAAA---LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASlerrksnipa 440

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1306 -VQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKEL----QELLVKSQ------------ENEGNLQGESLA 1368
Cdd:COG4913  441 rLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAIERVLggfaLTLLVPPEhyaaalrwvnrlHLRGRLVYERVR 520

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1369 VTEKLQQLEQAN-GELKEALCQKENGLKE-LQGKLDESNTV--------------------LESQKKSHNEIQD------ 1420
Cdd:COG4913  521 TGLPDPERPRLDpDSLAGKLDFKPHPFRAwLEAELGRRFDYvcvdspeelrrhpraitragQVKGNGTRHEKDDrrrirs 600

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1421 ----------KLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF------DTQLAEYQKVIDEM 1484
Cdd:COG4913  601 ryvlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidvasaEREIAELEAELERL 680

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1485 DDAasvkSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLEleksREVLSLKAQMNGASSRsgkGDEVESL 1564
Cdd:COG4913  681 DAS----SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAE----EELDELQDRLEAAEDL---ARLELRA 749

                        490       500       510
                 ....*....|....*....|....*....|....*...
gi 24584806 1565 DIETSLAKI---NFLNSIIADMQQKNDALKAKVQTLET 1599
Cdd:COG4913  750 LLEERFAAAlgdAVERELRENLEERIDALRARLNRAEE 787
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 681-1479 1.77e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 63.14  E-value: 1.77e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    681 VQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEI 760
Cdd:TIGR00606  185 IKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKI 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    761 -KAQNTQKDFELVEsgESLKKLQQQLEQKTLG-HEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESalKVVQVQL 838
Cdd:TIGR00606  265 mKLDNEIKALKSRK--KQMEKDNSELELKMEKvFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNK--ERRLLNQ 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    839 EQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSK-------QLEAANGSLEEEAKKSGHLLEQ 911
Cdd:TIGR00606  341 EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQiknfhtlVIERQEDEAKTAAQLCADLQSK 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    912 ITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHT 991
Cdd:TIGR00606  421 ERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLK 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    992 KLSKFsdeIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEN 1071
Cdd:TIGR00606  501 KEVKS---LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1072 LELSTGTQttIKDLQERLEITNAELQHKEKMA----SEDAQKIADLKTLVEAI------QVANANISATNAELSTVLEVL 1141
Cdd:TIGR00606  578 WLHSKSKE--INQTRDRLAKLNKELASLEQNKnhinNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQR 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1142 QAEKSETNHIFELFEMEADMNSE--RLIEKVTGIKEELKETHLQLderQKKFEELEEKLKQAQQSEQKLQQESQTSKEKL 1219
Cdd:TIGR00606  656 AMLAGATAVYSQFITQLTDENQSccPVCQRVFQTEAELQEFISDL---QSKLRLAPDKLKSTESELKKKEKRRDEMLGLA 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1220 TEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKET---QDQLLESQKKEKQLQEEA 1296
Cdd:TIGR00606  733 PGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVtimERFQMELKDVERKIAQQA 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1297 AKLSGElqqvqeangDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQL 1376
Cdd:TIGR00606  813 AKLQGS---------DLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1377 EQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKS 1456
Cdd:TIGR00606  884 QQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENK 963

                          810       820
                   ....*....|....*....|....*...
gi 24584806   1457 LQQ--KQLLLEKGNEFDT---QLAEYQK 1479
Cdd:TIGR00606  964 IQDgkDDYLKQKETELNTvnaQLEECEK 991
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
389-993 2.19e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.63  E-value: 2.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  389 LDREDAQNQALQLQKNINELKarivELESALDNERKKTEELQcsideaqfcgdELNAQSQVYKEKIHDLEsKITKLVSAT 468
Cdd:COG4913  218 LEEPDTFEAADALVEHFDDLE----RAHEALEDAREQIELLE-----------PIRELAERYAAARERLA-ELEYLRAAL 281

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  469 PSLQSILppdlpsDDGALQEEIAKLQE---KMTIQQKEVESRIAEQLEEEQRLRENVKYL-NEQIATLQSELVSKDEALE 544
Cdd:COG4913  282 RLWFAQR------RLELLEAELEELRAelaRLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELE 355

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  545 KfslsecgienlrreleLLKEENEKQAQEAQAEFTRKLAEKSVEVLRlsselQNLKATSDSLESERvnktdecEILQTEV 624
Cdd:COG4913  356 E----------------RERRRARLEALLAALGLPLPASAEEFAALR-----AEAAALLEALEEEL-------EALEEAL 407

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  625 RMRDEQIRELNQQLDEVTTQLNVQKADSSALD-DMLRLQKEGTEEkstlLEKTEK------ELVQSKEQAAKTLNDKEQL 697
Cdd:COG4913  408 AEAEAALRDLRRELRELEAEIASLERRKSNIPaRLLALRDALAEA----LGLDEAelpfvgELIEVRPEEERWRGAIERV 483

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  698 -----------EKQISDLKQLAEQEKL--------VREMTENAINQiQLEKESIEQQLALKQNELEDFqkkqsesevhLQ 758
Cdd:COG4913  484 lggfaltllvpPEHYAAALRWVNRLHLrgrlvyerVRTGLPDPERP-RLDPDSLAGKLDFKPHPFRAW----------LE 552

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  759 EIKAQntQKDFELVESGESLKKLQQ------QLEQKTLGHEK---------------LQAALEELKKEketiIKEKEQEL 817
Cdd:COG4913  553 AELGR--RFDYVCVDSPEELRRHPRaitragQVKGNGTRHEKddrrrirsryvlgfdNRAKLAALEAE----LAELEEEL 626

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  818 QQLQSKSAESESALKVVQVQLEQLQQQAAASGEEgsKTVAKLHDEISQLksqaEETQSELKSTQSNLEAKSKQLEAANGS 897
Cdd:COG4913  627 AEAEERLEALEAELDALQERREALQRLAEYSWDE--IDVASAEREIAEL----EAELERLDASSDDLAALEEQLEELEAE 700

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  898 LEEeakksghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHA 977
Cdd:COG4913  701 LEE-------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEE 773

                        650
                 ....*....|....*.
gi 24584806  978 ELQAERSSSSALHTKL 993
Cdd:COG4913  774 RIDALRARLNRAEEEL 789
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1092-1593 3.31e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 61.66  E-value: 3.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1092 TNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERlIEKVT 1171
Cdd:pfam05483   97 IEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEK-TKKYE 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1172 GIKEELKETHLQLDER-QKKFEELEEKLKQAQQSEQKLQQESQTSKEKlteIQQSLQELQDSVKQKEELVQNL------- 1243
Cdd:pfam05483  176 YEREETRQVYMDLNNNiEKMILAFEELRVQAENARLEMHFKLKEDHEK---IQHLEEEYKKEINDKEKQVSLLliqitek 252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1244 EEKVRESSSIIEAQNTKLNesnvQLENKTsclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1323
Cdd:pfam05483  253 ENKMKDLTFLLEESRDKAN----QLEEKT---KLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKT 325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1324 VKVLEEKLQAATSQLDAQQATNK-----------ELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKEN 1392
Cdd:pfam05483  326 ICQLTEEKEAQMEELNKAKAAHSfvvtefeattcSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEV 405

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1393 GLKELQGKLDESNTVLESQK---KSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNE 1469
Cdd:pfam05483  406 ELEELKKILAEDEKLLDEKKqfeKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKL 485

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1470 FDTQLA--------EYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAyletKELRRQLESLELEKSREV 1541
Cdd:pfam05483  486 KNIELTahcdklllENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE----MNLRDELESVREEFIQKG 561

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806   1542 LSLKAQMNgASSRSGKGDEVESLDIETSLA-----------KINFLNSIIADMQQKNDALKAK 1593
Cdd:pfam05483  562 DEVKCKLD-KSEENARSIEYEVLKKEKQMKilenkcnnlkkQIENKNKNIEELHQENKALKKK 623
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1361-1600 3.40e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 3.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1361 NLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLA 1440
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1441 EQLSQLKQANEELQKSLQQKQLLLEkgnEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAY 1520
Cdd:COG1196  316 ERLEELEEELAELEEELEELEEELE---ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1521 LETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLETL 1600
Cdd:COG1196  393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 405-1523 3.61e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 61.99  E-value: 3.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    405 INELKARIVELESALDNERKKTEELQCS----IDE--AQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILppd 478
Cdd:TIGR01612 1113 INKIKDDIKNLDQKIDHHIKALEEIKKKsenyIDEikAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKNIY--- 1189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    479 lpSDDGALQEEIAKLQEKMTIQQ----------KEVESRIAEQLEEEQRLRENVkylneqIATLQSELVSKDEALEKFSL 548
Cdd:TIGR01612 1190 --DEIKKLLNEIAEIEKDKTSLEevkginlsygKNLGKLFLEKIDEEKKKSEHM------IKAMEAYIEDLDEIKEKSPE 1261

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    549 SECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSelqnLKATSDSLESERVNktDECEILQTEVRMRD 628
Cdd:TIGR01612 1262 IENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKS----LKIIEDFSEESDIN--DIKKELQKNLLDAQ 1335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    629 EQIRELNQQLDEVTTQLNVQKadssalddmlrlqkegteekstlLEKTEKELVQSKEQAaktlNDKEQLEKQISDlkQLA 708
Cdd:TIGR01612 1336 KHNSDINLYLNEIANIYNILK-----------------------LNKIKKIIDEVKEYT----KEIEENNKNIKD--ELD 1386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    709 EQEKLVREMTENAinQIQLEKESIEQQLALKqnELEDFQKKQSESEVHlqeIKAQNTQKDFELVESGESLKKLQQQLEQK 788
Cdd:TIGR01612 1387 KSEKLIKKIKDDI--NLEECKSKIESTLDDK--DIDECIKKIKELKNH---ILSEESNIDTYFKNADENNENVLLLFKNI 1459

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    789 TLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSaeseSALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLks 868
Cdd:TIGR01612 1460 EMADNKSQHILKIKKDNATNDHDFNINELKEHIDKS----KGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSAL-- 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    869 qaeETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALE 948
Cdd:TIGR01612 1534 ---AIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFL 1610

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    949 KVnkeyaesraeaSDLQDKVKE-ITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAwSQEMLQKEKELQE 1027
Cdd:TIGR01612 1611 KI-----------SDIKKKINDcLKETESIEKKISSFSIDSQDTELKENGDNLNSLQEFLESLKDQ-KKNIEDKKKELDE 1678

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1028 LRQQLQdsqdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLE-LSTGTQTTIKDLQERLEITNAE-LQHKEKMASE 1105
Cdd:TIGR01612 1679 LDSEIE-------KIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIEsIKELIEPTIENLISSFNTNDLEgIDPNEKLEEY 1751

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1106 DAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNS---ERLIEKVTGIKEELKEthl 1182
Cdd:TIGR01612 1752 NTEIGDIYEEFIELYNIIAGCLETVSKEPITYDEIKNTRINAQNEFLKIIEIEKKSKSyldDIEAKEFDRIINHFKK--- 1828

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1183 QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKlteiqqslQELQDSVKQKEELVQNLEEKV-----RESSSIIEAQ 1257
Cdd:TIGR01612 1829 KLDHVNDKFTKEYSKINEGFDDISKSIENVKNSTDE--------NLLFDILNKTKDAYAGIIGKKyysykDEAEKIFINI 1900

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1258 NTKLNESNVQLENKT--SCLKETQDQLLESQKKEKqlqEEAAKLSGELQQVQEANGDIKDSLVKVEELVKvleeklqaat 1335
Cdd:TIGR01612 1901 SKLANSINIQIQNNSgiDLFDNINIAILSSLDSEK---EDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFK---------- 1967

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1336 sqldAQQATNKELQELLvksqenegNLQGESLAVTEKLQQLEQANGELKEALCQKE---NGLKELQGKLDESN------- 1405
Cdd:TIGR01612 1968 ----KSQDLHKKEQDTL--------NIIFENQQLYEKIQASNELKDTLSDLKYKKEkilNDVKLLLHKFDELNklscdsq 2035

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1406 ---TVLESQKksHNEIQDKLEQAQQKERTL--QEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKV 1480
Cdd:TIGR01612 2036 nydTILELSK--QDKIKEKIDNYEKEKEKFgiDFDVKAMEEKFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNIIQSKKK 2113

                         1130      1140      1150      1160
                   ....*....|....*....|....*....|....*....|...
gi 24584806   1481 IDEMDDAASVKsalLEQLQNRVAELETALRQANDAQKTAYLET 1523
Cdd:TIGR01612 2114 LKELTEAFNTE---IKIIEDKIIEKNDLIDKLIEMRKECLLFS 2153
PTZ00121 PTZ00121
MAEBL; Provisional
 375-974 3.66e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 3.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   375 EKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTE----ELQCSIDEAQFCGDELNA---QS 447
Cdd:PTZ00121 1294 EAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaakaEAEAAADEAEAAEEKAEAaekKK 1373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   448 QVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQKEV-----------ESRIAEQLE--- 513
Cdd:PTZ00121 1374 EEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKkkadeakkkaeEAKKADEAKkka 1453

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   514 EEQRLRENVKYLNEQIATLQSelvSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLS 593
Cdd:PTZ00121 1454 EEAKKAEEAKKKAEEAKKADE---AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   594 SE---LQNLKATSDSLESERVNKTDECEILQtEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKS 670
Cdd:PTZ00121 1531 EEakkADEAKKAEEKKKADELKKAEELKKAE-EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   671 TLLEKTEKELVQSKEqaaktLNDKEQLEKQISDLKQLAEQEK-----LVREMTENAINQIQLEKESIEQQLALKQNELED 745
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEE-----LKKAEEEKKKVEQLKKKEAEEKkkaeeLKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   746 FQKKQSESEVHLQEIKAQNTQ----KDFELVESGESLKKLQQQLEQKTlghEKLQAALEELKKEKETIIKEKEQELQQLQ 821
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKAEelkkKEAEEKKKAEELKKAEEENKIKA---EEAKKEAEEDKKKAEEAKKDEEEKKKIAH 1761

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   822 SKSAESESALKVVQVQLEQLQQQAAASGE----EGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGS 897
Cdd:PTZ00121 1762 LKKEEEKKAEEIRKEKEAVIEEELDEEDEkrrmEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM 1841

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806   898 LEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANaALEKVNKEYAESRAEASDLQDKVKEITDT 974
Cdd:PTZ00121 1842 QLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEAD-EIEKIDKDDIEREIPNNNMAGKNNDIIDD 1917
PTZ00121 PTZ00121
MAEBL; Provisional
 488-1190 3.89e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 3.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   488 EEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKfslsecgiENLRRELELLKEEN 567
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA--------EAEAAADEAEAAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   568 EKQAQEAQAEFTRKLAE---KSVEVLRLSSELQNlKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQldevttq 644
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADaakKKAEEKKKADEAKK-KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEA------- 1436

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   645 lnVQKADSSALDDMLRLQKEGTEEKSTLLEKTEkelvqsKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQ 724
Cdd:PTZ00121 1437 --KKKAEEAKKADEAKKKAEEAKKAEEAKKKAE------EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA 1508

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   725 IQLEKESIEQQLALKQNELEDFQKKQSESEVH-LQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAAlEELK 803
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEEAKKADEAKkAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA-EEAK 1587

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   804 KEKETIIKEKEQELQQLQSKSAEsesalKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSN 883
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAE-----EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   884 LEAKSKQleaangslEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASD 963
Cdd:PTZ00121 1663 AAEEAKK--------AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEE 1734

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   964 LQDKVKEitDTLHAElqaERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKElqelrqqlqdsqdsqtKLK 1043
Cdd:PTZ00121 1735 AKKEAEE--DKKKAE---EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDE----------------KRR 1793

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1044 AEGERKEKSFEESIKNLQEevtKAKTENLELSTGTQTTIKDLQERLEITNAELqhkekmasEDAQKIADLKTLVEAIQVA 1123
Cdd:PTZ00121 1794 MEVDKKIKDIFDNFANIIE---GGKEGNLVINDSKEMEDSAIKEVADSKNMQL--------EEADAFEKHKFNKNNENGE 1862

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806  1124 NANISATNAELSTVLEVLQAEKSETNHIFELfeMEADMNSERLIEKVTGIKEELKETHLQLDERQKK 1190
Cdd:PTZ00121 1863 DGNKEADFNKEKDLKEDDEEEIEEADEIEKI--DKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKR 1927
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 662-895 4.09e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.55  E-value: 4.09e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  662 QKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDL-KQLAEQEKLVREmTENAINQIQLEKESIEQQLALKQ 740
Cdd:COG4942   18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALeRRIAALARRIRA-LEQELAALEAELAELEKEIAELR 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  741 NELEDFQKKQSESEVHLQEIKAQNT------QKDFELVESG--------ESLKKLQQQLEQKTLGHEKLQAALEELKKEK 806
Cdd:COG4942   97 AELEAQKEELAELLRALYRLGRQPPlalllsPEDFLDAVRRlqylkylaPARREQAEELRADLAELAALRAELEAERAEL 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  807 ETIIKEKEQELQQLQSKSAESESALKVVqvqleqlqqqaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEA 886
Cdd:COG4942  177 EALLAELEEERAALEALKAERQKLLARL------------------EKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                 ....*....
gi 24584806  887 KSKQLEAAN 895
Cdd:COG4942  239 AAERTPAAG 247
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 588-1339 4.19e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 61.78  E-value: 4.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    588 EVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNvQKADSSALDdmLRLQKEGTE 667
Cdd:pfam12128  242 EFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWK-EKRDELNGE--LSAADAAVA 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    668 EKSTLLEKTEKELVQSKEQAAKTLN-DKEQLEKQISDLKQLAEQEKLVremtENAINQIQLEKESIEQQLALKQN-ELED 745
Cdd:pfam12128  319 KDRSELEALEDQHGAFLDADIETAAaDQEQLPSWQSELENLEERLKAL----TGKHQDVTAKYNRRRSKIKEQNNrDIAG 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    746 FQKKQSesevhlqeikAQNTQKDFELVESGESLKKLQQQLeqktlgHEKLQAALEELKKEKETIIKEKEQELQQLQSKSA 825
Cdd:pfam12128  395 IKDKLA----------KIREARDRQLAVAEDDLQALESEL------REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATA 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    826 ESEsaLKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELK-------STQSNLEAKSKQLEAANGSL 898
Cdd:pfam12128  459 TPE--LLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRqasrrleERQSALDELELQLFPQAGTL 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    899 EEEAKKSGHLLEQitklksEVGETQAALSSCHTD-----VESKTKQ---LEAANAALEKVNKEyaesraEASDLQDKVKE 970
Cdd:pfam12128  537 LHFLRKEAPDWEQ------SIGKVISPELLHRTDldpevWDGSVGGelnLYGVKLDLKRIDVP------EWAASEEELRE 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    971 ITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQemlqKEKELQELRQQLqdsqdsqtklKAEGERKE 1050
Cdd:pfam12128  605 RLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKN----ARLDLRRLFDEK----------QSEKDKKN 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1051 KSFEESIKNLQEEVTKAKTENLELStgtqttiKDLQERLEitnaelQHKEKMASEDAQKIADLKTLVEAIQVANANISAT 1130
Cdd:pfam12128  671 KALAERKDSANERLNSLEAQLKQLD-------KKHQAWLE------EQKEQKREARTEKQAYWQVVEGALDAQLALLKAA 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1131 NAelstvlevlqaeKSETNHIFELFEMEADMNSERlieKVTGIKEElkethlQLDERQKKFEELEEKLKQAQQSEQKLQQ 1210
Cdd:pfam12128  738 IA------------ARRSGAKAELKALETWYKRDL---ASLGVDPD------VIAKLKREIRTLERKIERIAVRRQEVLR 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1211 -----------ESQTSKEKLTEIQQSLQELQDSVKQKEElvqnleekvresssiieaqNTKLNESNVQLENKTSclKETQ 1279
Cdd:pfam12128  797 yfdwyqetwlqRRPRLATQLSNIERAISELQQQLARLIA-------------------DTKLRRAKLEMERKAS--EKQQ 855

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1280 DQLLESQKKEKQLQEEAAKLSgELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLD 1339
Cdd:pfam12128  856 VRLSENLRGLRCEMSKLATLK-EDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVE 914
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 998-1599 4.56e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.62  E-value: 4.56e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    998 DEIAtGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEK---------SFEESIKNLQEEVTKAK 1068
Cdd:TIGR02169  160 DEIA-GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqallkekrEYEGYELLKEKEALERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1069 TENLELSTGTQT-TIKDLQERLEITNAELQHKEKMASEDAQKIADL--------KTLVEAIQVANANISATNAELStvLE 1139
Cdd:TIGR02169  239 KEAIERQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeqlrvKEKIGELEAEIASLERSIAEKE--RE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1140 VLQAEKSETNHIFELFEMEADM-NSERLIE----KVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQT 1214
Cdd:TIGR02169  317 LEDAEERLAKLEAEIDKLLAEIeELEREIEeerkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1215 SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQE 1294
Cdd:TIGR02169  397 LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1295 EAAKLSGELQQVQE--------------------ANGDIKDSLVK-----VEELVKVlEEKLQAAT-------------- 1335
Cdd:TIGR02169  477 EYDRVEKELSKLQRelaeaeaqaraseervrggrAVEEVLKASIQgvhgtVAQLGSV-GERYATAIevaagnrlnnvvve 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1336 SQLDAQQATN--KELQ---------------------------------------------------ELLVKSQEN---- 1358
Cdd:TIGR02169  556 DDAVAKEAIEllKRRKagratflplnkmrderrdlsilsedgvigfavdlvefdpkyepafkyvfgdTLVVEDIEAarrl 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1359 ---------EGNLQGESLAVT---EKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQ 1426
Cdd:TIGR02169  636 mgkyrmvtlEGELFEKSGAMTggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1427 QKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEkgnEFDTQLAEYQKVIDEMDDAasvksalLEQLQNRVAELE 1506
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE---NVKSELKELEARIEELEED-------LHKLEEALNDLE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1507 TALRQAndaqktaylETKELRRQLESLELEKSREVLSLkAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQK 1586
Cdd:TIGR02169  786 ARLSHS---------RIPEIQAELSKLEEEVSRIEARL-REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE 855

                          730
                   ....*....|...
gi 24584806   1587 NDALKAKVQTLET 1599
Cdd:TIGR02169  856 IENLNGKKEELEE 868
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1090-1536 5.98e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 60.94  E-value: 5.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1090 EITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANIsatnAELSTVLEVLQAEKSETNHIFELFEMEADMNS-ERLIE 1168
Cdd:COG4717   67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL----EELEAELEELREELEKLEKLLQLLPLYQELEAlEAELA 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1169 KVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQS-EQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKV 1247
Cdd:COG4717  143 ELPERLEELEERLEELRELEEELEELEAELAELQEElEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1248 RESSSIIEaqntklnesnvQLENKtsclketqdqlLESQKKEKQLQEEAAKLS--GELQQVQEANGDIKDSLVKVEELVK 1325
Cdd:COG4717  223 EELEEELE-----------QLENE-----------LEAAALEERLKEARLLLLiaAALLALLGLGGSLLSLILTIAGVLF 280

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1326 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1405
Cdd:COG4717  281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1406 TVLEsQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEfDTQLAEYQKVIDEMD 1485
Cdd:COG4717  361 EELQ-LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLE-ALDEEELEEELEELE 438

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 24584806 1486 DAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETK--ELRRQLESLELE 1536
Cdd:COG4717  439 EELEELEEELEELREELAELEAELEQLEEDGELAELLQEleELKAELRELAEE 491
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1128-1469 7.17e-09

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 60.52  E-value: 7.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1128 SATNAELSTVLEVLQAEKS--ETNHIFELFEMEAdmnserlieKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSE 1205
Cdd:pfam05557    1 RAELIESKARLSQLQNEKKqmELEHKRARIELEK---------KASALKRQLDRESDRNQELQKRIRLLEKREAEAEEAL 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1206 QKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLES 1285
Cdd:pfam05557   72 REQAELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEA 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1286 QKKEKQLQEEAAKLSGELQQVQEANGDIKdSLVKVEELVKVLEEKLqAATSQLDAQQATNKELQELLVKSQENEGNLQGE 1365
Cdd:pfam05557  152 EQLRQNLEKQQSSLAEAEQRIKELEFEIQ-SQEQDSEIVKNSKSEL-ARIPELEKELERLREHNKHLNENIENKLLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1366 SLAVTEKLQQLEQANGELKEALCQKENGLKELQG--KLDESNTVlesQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL 1443
Cdd:pfam05557  230 VEDLKRKLEREEKYREEAATLELEKEKLEQELQSwvKLAQDTGL---NLRSPEDLSRRIEQLQQREIVLKEENSSLTSSA 306

                          330       340
                   ....*....|....*....|....*....
gi 24584806   1444 SQLKQANEELQ---KSLQQKQLLLEKGNE 1469
Cdd:pfam05557  307 RQLEKARRELEqelAQYLKKIEDLNKKLK 335
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1167-1548 9.81e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 60.17  E-value: 9.81e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1167 IEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQtSKEKLTEIQQSLQELQDSVKQKEELVQNLEEK 1246
Cdd:COG4717   73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-KLEKLLQLLPLYQELEALEAELAELPERLEEL 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1247 VRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKV 1326
Cdd:COG4717  152 EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1327 LEEKL--QAATSQLDAQQATNKELQELLV---------KSQENEGNLQGESLAV------------TEKLQQLEQANG-E 1382
Cdd:COG4717  232 LENELeaAALEERLKEARLLLLIAAALLAllglggsllSLILTIAGVLFLVLGLlallflllarekASLGKEAEELQAlP 311

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1383 LKEALCQKE--NGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETS--KLAEQLSQLKQANEE----LQ 1454
Cdd:COG4717  312 ALEELEEEEleELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELeqEIAALLAEAGVEDEEelraAL 391

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1455 KSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASvksalLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1534
Cdd:COG4717  392 EQAEEYQELKEELEELEEQLEELLGELEELLEALD-----EEELEEELEELEEELEELEEELEELREELAELEAELEQLE 466

                        410
                 ....*....|....
gi 24584806 1535 LEKSREVLSLKAQM 1548
Cdd:COG4717  467 EDGELAELLQELEE 480
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 667-1537 1.10e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 60.35  E-value: 1.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  667 EEKSTLLEKT---EKELVQSKEQAAktlNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQ--LALKQN 741
Cdd:COG3096  278 NERRELSERAlelRRELFGARRQLA---EEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQekIERYQE 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  742 ELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQL--------EQKTLGHEKLQA--ALEELK-------- 803
Cdd:COG3096  355 DLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLadyqqaldVQQTRAIQYQQAvqALEKARalcglpdl 434

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  804 -----KEKETIIKEKEQELQQ----LQSKSAESESALKVVqvqleqlqqqaaasgEEGSKTVAKLHDEISqlKSQAEETQ 874
Cdd:COG3096  435 tpenaEDYLAAFRAKEQQATEevleLEQKLSVADAARRQF---------------EKAYELVCKIAGEVE--RSQAWQTA 497

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  875 SELKSTQSNLEAKSKQLEAANGSLEEEAKksghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 954
Cdd:COG3096  498 RELLRRYRSQQALAQRLQQLRAQLAELEQ----RLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQA 573

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  955 AESRAEASDLQDKVKEITdTLHAELQAERSSSSALHTKLSKFSDEIatgHKELTSKAD--AWSQEMLQKEKELQELRQQL 1032
Cdd:COG3096  574 AEAVEQRSELRQQLEQLR-ARIKELAARAPAWLAAQDALERLREQS---GEALADSQEvtAAMQQLLEREREATVERDEL 649

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1033 QdsqdsqtklkaegERKEkSFEESIKNLQEevtKAKTENLELSTgtqttikdLQERLeitNAELQHK--EKMASEDAQKI 1110
Cdd:COG3096  650 A-------------ARKQ-ALESQIERLSQ---PGGAEDPRLLA--------LAERL---GGVLLSEiyDDVTLEDAPYF 701

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1111 -ADLKTLVEAIQVAnanisatnaELSTVLEVLQAEKSETNHIFeLFEMEADMNSERLIEKvtgikEELKETHL-QLDERQ 1188
Cdd:COG3096  702 sALYGPARHAIVVP---------DLSAVKEQLAGLEDCPEDLY-LIEGDPDSFDDSVFDA-----EELEDAVVvKLSDRQ 766

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1189 ---KKFEEL--------EEKLKqaqqseqKLQQESQTSKEKLTEIQQSLQELQdsvkqkeELVQNLEEKVRESSSII--- 1254
Cdd:COG3096  767 wrySRFPEVplfgraarEKRLE-------ELRAERDELAEQYAKASFDVQKLQ-------RLHQAFSQFVGGHLAVAfap 832

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1255 --EAQNTKLNESNVQLEnktsclketqDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIkdSLVK---VEELVKVLEE 1329
Cdd:COG3096  833 dpEAELAALRQRRSELE----------RELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQA--NLLAdetLADRLEELRE 900

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1330 KLQAATSQ---LDAQQATNKELQELLVKSQ---ENEGNLQGESLAVTEKLQQLEQANGELKEALCQKEN-GLKELQGKLD 1402
Cdd:COG3096  901 ELDAAQEAqafIQQHGKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHfSYEDAVGLLG 980

                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1403 ESNTVLESqkkshneIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLekgNEFDTQLAEYQKVID 1482
Cdd:COG3096  981 ENSDLNEK-------LRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTL---QELEQELEELGVQAD 1050

                        890       900       910       920       930
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 24584806 1483 emDDAAsvksallEQLQNRVAELETALRQaNDAQKTaYLETKELRRQLESLELEK 1537
Cdd:COG3096 1051 --AEAE-------ERARIRRDELHEELSQ-NRSRRS-QLEKQLTRCEAEMDSLQK 1094
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 401-1485 1.25e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 60.45  E-value: 1.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    401 LQKNINELKArIVElESALDN--ERKKTEELQCSIDEAQfcgDEL-NAQSQVYKEKIHDLESKITKLVSATPSLQSILpp 477
Cdd:TIGR01612  673 IDALYNELSS-IVK-ENAIDNteDKAKLDDLKSKIDKEY---DKIqNMETATVELHLSNIENKKNELLDIIVEIKKHI-- 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    478 dlpsdDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRenvKYlNEQIATLQSELvskdealekfslsecgieNLR 557
Cdd:TIGR01612  746 -----HGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELN---KY-KSKISEIKNHY------------------NDQ 798

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    558 RELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECeilQTEVRMRDEQIREL-NQ 636
Cdd:TIGR01612  799 INIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNC---KEKIDSEHEQFAELtNK 875

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    637 QLDEVT-TQLNVQKA---DSSALDDMLRLQKEGTEEKSTLLEKTEK--ELVQSKEQAAKTLNDK-----EQLEKQISDLK 705
Cdd:TIGR01612  876 IKAEISdDKLNDYEKkfnDSKSLINEINKSIEEEYQNINTLKKVDEyiKICENTKESIEKFHNKqnilkEILNKNIDTIK 955

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    706 QLAEQEKLVREMTENA-INQI-QLEKesieqqlALKQNELEDFQKKQSESEVHLQEIKAQ-NTQKDFELVESGESLKKLQ 782
Cdd:TIGR01612  956 ESNLIEKSYKDKFDNTlIDKInELDK-------AFKDASLNDYEAKNNELIKYFNDLKANlGKNKENMLYHQFDEKEKAT 1028

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    783 QQLEQKTlghEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESesalkvvQVQLEQLQQQAAASGEEGSKTVAKLHDE 862
Cdd:TIGR01612 1029 NDIEQKI---EDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIEL-------LNKEILEEAEINITNFNEIKEKLKHYNF 1098

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    863 ISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSghlleqitklksevgetqaalsschtdvESKTKQLEA 942
Cdd:TIGR01612 1099 DDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKS----------------------------ENYIDEIKA 1150

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    943 ANAALEKVnkeyaesrAEASDLQDKVKEITDTLHaELQAERSSSSALHTKLSKFSDEIATGHKELTSkadawsqemLQKE 1022
Cdd:TIGR01612 1151 QINDLEDV--------ADKAISNDDPEEIEKKIE-NIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS---------LEEV 1212

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1023 KELQeLRQQLQDSQDSQTKLKAEGERKE---KSFEESIKNLQEevTKAKTENLELSTGTQTTIKDLQERLEITNAELQHK 1099
Cdd:TIGR01612 1213 KGIN-LSYGKNLGKLFLEKIDEEKKKSEhmiKAMEAYIEDLDE--IKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDH 1289

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1100 EKMASEDAQKIADLKTLVEAIQVAN---ANISATNAELSTVLEVLQAEKSETN----HIFELFEMEADMNSERLIEKVTG 1172
Cdd:TIGR01612 1290 HIISKKHDENISDIREKSLKIIEDFseeSDINDIKKELQKNLLDAQKHNSDINlylnEIANIYNILKLNKIKKIIDEVKE 1369

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1173 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQ-KLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESS 1251
Cdd:TIGR01612 1370 YTKEIEENNKNIKDELDKSEKLIKKIKDDINLEEcKSKIESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENN 1449

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1252 siieaQNTKLNESNVQL-ENKTSCLKETQ------------DQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLV 1318
Cdd:TIGR01612 1450 -----ENVLLLFKNIEMaDNKSQHILKIKkdnatndhdfniNELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVT 1524

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1319 KVEELVKVLEEKLQAATSQLDAQQATN--KELQELLV----KSQENEGNLQGESLAVTEKLQQLEQANgelkEALCQKEN 1392
Cdd:TIGR01612 1525 ELLNKYSALAIKNKFAKTKKDSEIIIKeiKDAHKKFIleaeKSEQKIKEIKKEKFRIEDDAAKNDKSN----KAAIDIQL 1600

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1393 GLKELQGKLDESNTVlesqKKSHNEIQDKLEQAQQKERTLQEET--SKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF 1470
Cdd:TIGR01612 1601 SLENFENKFLKISDI----KKKINDCLKETESIEKKISSFSIDSqdTELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676

                         1130
                   ....*....|....*
gi 24584806   1471 DTQLAEYQKVIDEMD 1485
Cdd:TIGR01612 1677 DELDSEIEKIEIDVD 1691
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1164-1542 1.53e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 59.40  E-value: 1.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1164 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSK--EKLTEIQQSLQELQ---DSVKQKEE 1238
Cdd:COG4717   77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPerlEELEERLE 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1239 LVQNLEEKVRESSSIIEAQNTKLNESNVQLENKT-SCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSL 1317
Cdd:COG4717  157 ELRELEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1318 VKVEELVKVLEEK-LQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALcQKENGLKE 1396
Cdd:COG4717  237 EAAALEERLKEARlLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL-QALPALEE 315

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1397 LQGKldESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQkslqQKQLLLEKGNEFDTQLAE 1476
Cdd:COG4717  316 LEEE--ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQE----IAALLAEAGVEDEEELRA 389

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806 1477 YQKVIDEMDDAAsvksALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVL 1542
Cdd:COG4717  390 ALEQAEEYQELK----EELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEEL 451
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 125-185 1.56e-08

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 59.70  E-value: 1.56e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806  125 IGQRVWLGGTRpGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSR 185
Cdd:COG5244    6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIR 65
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 874-1560 1.65e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 59.97  E-value: 1.65e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  874 QSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTdvesKTKQLEAANAALEKvnke 953
Cdd:COG3096  353 QEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQT----RAIQYQQAVQALEK---- 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  954 yAESRAEASDL-QDKVKEITDTLHAELQAERSSSSALHTKLSkFSDEIATGHKEL----------TSKADAWS--QEMLq 1020
Cdd:COG3096  425 -ARALCGLPDLtPENAEDYLAAFRAKEQQATEEVLELEQKLS-VADAARRQFEKAyelvckiageVERSQAWQtaRELL- 501

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1021 keKELQELRQQLQDSQDSQTKLkAEGERKEKSfEESIKNLQEEVTKAKTENLElstgTQTTIKDLQERLEITNAELqhkE 1100
Cdd:COG3096  502 --RRYRSQQALAQRLQQLRAQL-AELEQRLRQ-QQNAERLLEEFCQRIGQQLD----AAEELEELLAELEAQLEEL---E 570

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1101 KMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfemeadmNSERLIEKVTGIKEELKET 1180
Cdd:COG3096  571 EQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALA--------DSQEVTAAMQQLLEREREA 642

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1181 HLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEK-----LTEIQQ--SLQE----------------LQDSVKQKE 1237
Cdd:COG3096  643 TVERDELAARKQALESQIERLSQPGGAEDPRLLALAERlggvlLSEIYDdvTLEDapyfsalygparhaivVPDLSAVKE 722

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1238 ELvQNLEEkVRESSSIIEAQNTKLNES--NVQLENKTSCLKETQDQLLESQ----------KKEKQLQ----------EE 1295
Cdd:COG3096  723 QL-AGLED-CPEDLYLIEGDPDSFDDSvfDAEELEDAVVVKLSDRQWRYSRfpevplfgraAREKRLEelraerdelaEQ 800

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1296 AAKLSGELQQVQEANGDIKDSLVK---------VEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQG-- 1364
Cdd:COG3096  801 YAKASFDVQKLQRLHQAFSQFVGGhlavafapdPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKll 880

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1365 --------ESLAvtEKLQQLEQANGELKEA---LCQKENGLKELQGKLDesntVLESQKKSHNEIQDKLEQAQQKERTLQ 1433
Cdd:COG3096  881 pqanlladETLA--DRLEELREELDAAQEAqafIQQHGKALAQLEPLVA----VLQSDPEQFEQLQADYLQAKEQQRRLK 954

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1434 EETSKLAE---------------QLSQLKQANEELQKSLQQKQLLLEKGNE----FDTQLAEYQKVIDEMDDAASVKSAL 1494
Cdd:COG3096  955 QQIFALSEvvqrrphfsyedavgLLGENSDLNEKLRARLEQAEEARREAREqlrqAQAQYSQYNQVLASLKSSRDAKQQT 1034

                        730       740       750       760       770       780       790
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806 1495 LEQLQNRVAELEtaLRQANDAQKTAYLETKELRRQLESL-----ELEKSREVlsLKAQMNGASSRSGKGDE 1560
Cdd:COG3096 1035 LQELEQELEELG--VQADAEAEERARIRRDELHEELSQNrsrrsQLEKQLTR--CEAEMDSLQKRLRKAER 1101
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
673-1409 1.86e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 1.86e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  673 LEKTEKELVQSKEQAaKTLndkEQLEKQISDLKQLAEQEKLVREM--------TENAINQIQLEKESIEQQLALKQNELE 744
Cdd:COG4913  237 LERAHEALEDAREQI-ELL---EPIRELAERYAAARERLAELEYLraalrlwfAQRRLELLEAELEELRAELARLEAELE 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  745 DFQKKQSESEVHLQEIKAQNTQKDfelvesGESLKKLQQQLEQKTLGHEKLQAALEELkkeketiikekEQELQQLQSKS 824
Cdd:COG4913  313 RLEARLDALREELDELEAQIRGNG------GDRLEQLEREIERLERELEERERRRARL-----------EALLAALGLPL 375

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  825 AESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSE---LKSTQSNLEAKS----KQLEAANGS 897
Cdd:COG4913  376 PASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEiasLERRKSNIPARLlalrDALAEALGL 455

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  898 LEEEAKKSGHLLEqitkLKSEVGETQAA----LSSCHTD--VESktkqlEAANAALEKVNKEYAESRaeasdLQ-DKVKE 970
Cdd:COG4913  456 DEAELPFVGELIE----VRPEEERWRGAiervLGGFALTllVPP-----EHYAAALRWVNRLHLRGR-----LVyERVRT 521

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  971 ITDTLHAELQAERSSSSALHTKLSKFSDEIatgHKELTSKADAWSQEmlqkekELQELRQqlqdsqdsqtklkaegerke 1050
Cdd:COG4913  522 GLPDPERPRLDPDSLAGKLDFKPHPFRAWL---EAELGRRFDYVCVD------SPEELRR-------------------- 572

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1051 ksfeesiknlqeeVTKAKTENLELSTGTQTTIKDLQERLEitnAELQhkekMASEDAQKIADLKTLVEAIQVANANISAT 1130
Cdd:COG4913  573 -------------HPRAITRAGQVKGNGTRHEKDDRRRIR---SRYV----LGFDNRAKLAALEAELAELEEELAEAEER 632

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1131 NAELSTVLEVLQAEKSETNHIFELFEMEADMNSerLIEKVTGIKEELKethlQLDERQKKFEELEEKLKQAQQSEQKLQQ 1210
Cdd:COG4913  633 LEALEAELDALQERREALQRLAEYSWDEIDVAS--AEREIAELEAELE----RLDASSDDLAALEEQLEELEAELEELEE 706

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1211 ESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVResssiiEAQNTKLnesnvqlenktsclketqDQLLESQKKEK 1290
Cdd:COG4913  707 ELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR------LELRALL------------------EERFAAALGDA 762

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1291 QLQEEAAKLSGELQQVQEANGDikdslvKVEELVKVLEEKLQ---AATSQLDAQQATNKELQELLVKsqenegnLQGESL 1367
Cdd:COG4913  763 VERELRENLEERIDALRARLNR------AEEELERAMRAFNRewpAETADLDADLESLPEYLALLDR-------LEEDGL 829

                        730       740       750       760
                 ....*....|....*....|....*....|....*....|....*
gi 24584806 1368 AVTEK--LQQLEQANGELKEALCQK-ENGLKELQGKLDESNTVLE 1409
Cdd:COG4913  830 PEYEErfKELLNENSIEFVADLLSKlRRAIREIKERIDPLNDSLK 874
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1017-1529 2.16e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 59.35  E-value: 2.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1017 EMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKaktenlelSTGTQTTIKDLQERLEITNAEL 1096
Cdd:pfam05483  100 ELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKE--------NNATRHLCNLLKETCARSAEKT 171

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1097 QHKEKMASEDAQKIADLKTLVEAIQVA--NANISATNAELSTVLEvLQAEKSETNHIFELFEMEADMNSER---LIEKVT 1171
Cdd:pfam05483  172 KKYEYEREETRQVYMDLNNNIEKMILAfeELRVQAENARLEMHFK-LKEDHEKIQHLEEEYKKEINDKEKQvslLLIQIT 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1172 GIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESS 1251
Cdd:pfam05483  251 EKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLT 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1252 SIIEAQNTKLNESN-------VQLENKTSCLKE---TQDQLLEsqKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVE 1321
Cdd:pfam05483  331 EEKEAQMEELNKAKaahsfvvTEFEATTCSLEEllrTEQQRLE--KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1322 ELVKVLEEKlqaaTSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGK- 1400
Cdd:pfam05483  409 ELKKILAED----EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEk 484

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1401 ------LDESNTVLESQKKSHNEIQD---KLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQ-KQLLLEKGNEF 1470
Cdd:pfam05483  485 lknielTAHCDKLLLENKELTQEASDmtlELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESvREEFIQKGDEV 564

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806   1471 DTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQ 1529
Cdd:pfam05483  565 KCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKK 623
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1187-1599 2.25e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 59.26  E-value: 2.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1187 RQKKFEELEEKLKQAQ----QSEQKL-------------------------QQESQ------TSKEKLTEIQQSLQELQD 1231
Cdd:TIGR04523   31 QDTEEKQLEKKLKTIKnelkNKEKELknldknlnkdeekinnsnnkikileQQIKDlndklkKNKDKINKLNSDLSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1232 SVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANG 1311
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNID 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1312 DIKDSLVKVEELVKVLEEKLQ---AATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALC 1388
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1389 QKENGLKELQGKLDESN----------TVLESQKKS--HNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKS 1456
Cdd:TIGR04523  271 EKQKELEQNNKKIKELEkqlnqlkseiSDLNNQKEQdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1457 LQQKQLlleKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDaqktaylETKELRRQLESLELE 1536
Cdd:TIGR04523  351 LTNSES---ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEK-------LNQQKDEQIKKLQQE 420

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806   1537 KSrevLSLKAQMNGASSRSGKGDEVESLDIETSLAK--INFLNSIIADMQQKNDALKAKVQTLET 1599
Cdd:TIGR04523  421 KE---LLEKEIERLKETIIKNNSEIKDLTNQDSVKEliIKNLDNTRESLETQLKVLSRSINKIKQ 482
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 801-1465 2.63e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 59.29  E-value: 2.63e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    801 ELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGS-------KTVAKLHDEISQL------- 866
Cdd:TIGR00606  109 EFKTLEGVITRYKHGEKVSLSSKCAEIDREMISHLGVSKAVLNNVIFCHQEDSnwplsegKALKQKFDEIFSAtryikal 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    867 ----------KSQAEETQSELKSTQSNLEAKSK---QLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHtDV 933
Cdd:TIGR00606  189 etlrqvrqtqGQKVQEHQMELKYLKQYKEKACEirdQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIM-KL 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    934 ESKTKQLEAANAALEKVNKEYAESRAEA-SDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKAD 1012
Cdd:TIGR00606  268 DNEIKALKSRKKQMEKDNSELELKMEKVfQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLV 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1013 AWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEnlELSTGTQTTikdlqerleit 1092
Cdd:TIGR00606  348 EQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQED--EAKTAAQLC----------- 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1093 nAELQHKEKMASEDAQKIADLKT-LVEAIQVANANISATNAELSTVLEVLQaeksetnhifelfemEADMNSERLIEKvt 1171
Cdd:TIGR00606  415 -ADLQSKERLKQEQADEIRDEKKgLGRTIELKKEILEKKQEELKFVIKELQ---------------QLEGSSDRILEL-- 476

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1172 giKEELKETHLQLDERQKKfeELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESS 1251
Cdd:TIGR00606  477 --DQELRKAERELSKAEKN--SLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIR 552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1252 SIIEAQNTKLNESNVQLENKtsclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKL 1331
Cdd:TIGR00606  553 KIKSRHSDELTSLLGYFPNK----KQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL 628

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1332 QAATSQlDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLE--------------QANGELKEALCQKENGLKEL 1397
Cdd:TIGR00606  629 FDVCGS-QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTdenqsccpvcqrvfQTEAELQEFISDLQSKLRLA 707

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806   1398 QGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLE 1465
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLG 775
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 368-1307 2.73e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.03  E-value: 2.73e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    368 SMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALdneRKKTEELQCSIDEAQfcgDELNAQS 447
Cdd:pfam01576  187 AMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQL---AKKEEELQAALARLE---EETAQKN 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    448 QVYKeKIHDLESKITKLvsatpslqsilppdlpsddgalqeeiaklqekmtiqQKEVESRIAEQLEEEQRLRENVKYLNE 527
Cdd:pfam01576  261 NALK-KIRELEAQISEL------------------------------------QEDLESERAARNKAEKQRRDLGEELEA 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    528 QIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLE 607
Cdd:pfam01576  304 LKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALE 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    608 SERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLN-VQKADSSALDDMLRLQKEgTEEKSTLLEKTEKELVQSKEQ 686
Cdd:pfam01576  384 SENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSeSERQRAELAEKLSKLQSE-LESVSSLLNEAEGKNIKLSKD 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    687 AAktlndkeQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQnTQ 766
Cdd:pfam01576  463 VS-------SLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKK-LE 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    767 KDFELVESG-ESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQA 845
Cdd:pfam01576  535 EDAGTLEALeEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEK 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    846 AASgeegsktvAKLHDEISQLKSQAEETQSELKSTqsnleakSKQLEAANGSLEEeakksghLLEQITKLKSEVGEtqaa 925
Cdd:pfam01576  615 AIS--------ARYAEERDRAEAEAREKETRALSL-------ARALEEALEAKEE-------LERTNKQLRAEMED---- 668

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    926 LSSCHTDVESKTKQLEAANAALEkvnkeyaesrAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHK 1005
Cdd:pfam01576  669 LVSSKDDVGKNVHELERSKRALE----------QQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDE 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1006 ELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTenlelstgTQTTIKDL 1085
Cdd:pfam01576  739 QGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKK--------LQAQMKDL 810

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1086 QERLEITNAELQHKEKMASEDAQKI----ADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfemeadm 1161
Cdd:pfam01576  811 QRELEEARASRDEILAQSKESEKKLknleAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQD-------- 882

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1162 NSERLIEKVTGIKEELKETHLQ---LDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKL----TEIQQSLQELQDSVK 1234
Cdd:pfam01576  883 EKRRLEARIAQLEEELEEEQSNtelLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLerqnKELKAKLQEMEGTVK 962

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24584806   1235 QKEEL-VQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQ 1307
Cdd:pfam01576  963 SKFKSsIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGNSRMKQLK 1036
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1280-1551 3.03e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.77  E-value: 3.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1280 DQLLEsqkkEKQLQEEAAKLSGELQQVQEAngdiKDSLVKVEELVKVLE------EKLQAATSQLDAQQATnKELQELLV 1353
Cdd:COG4913  215 EYMLE----EPDTFEAADALVEHFDDLERA----HEALEDAREQIELLEpirelaERYAAARERLAELEYL-RAALRLWF 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1354 KSQENEgnlqgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvLESQKKSHNeiQDKLEQAQQKERTLQ 1433
Cdd:COG4913  286 AQRRLE--------LLEAELEELRAELARLEAELERLEARLDALREELDE----LEAQIRGNG--GDRLEQLEREIERLE 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1434 EETSKLAEQLSQLKQANEELqkslqqkqlllekGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAN 1513
Cdd:COG4913  352 RELEERERRRARLEALLAAL-------------GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 24584806 1514 DaqktaylETKELRRQLESLELEKS---REVLSLKAQMNGA 1551
Cdd:COG4913  419 R-------ELRELEAEIASLERRKSnipARLLALRDALAEA 452
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1329-1558 3.23e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.85  E-value: 3.23e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1329 EKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVL 1408
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1409 ESQKKSHNEIQDKLEQAQQKERTL----QEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEM 1484
Cdd:COG4942  100 EAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24584806 1485 DDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKG 1558
Cdd:COG4942  180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
373-921 3.23e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 3.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   373 LREKQQHVEKLMVERDLDRE---DAQNQALQLQKNINELKARIVELESALDNERKKTEELQ------CSIDEAQFCGDEL 443
Cdd:PRK03918  219 LREELEKLEKEVKELEELKEeieELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEekvkelKELKEKAEEYIKL 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   444 NAQSQVYKEKIHDLESKITKLVSATPSLQSILppdlpSDDGALQEEIAKLQEKMtiqqKEVESRIAEqLEEEQRLRENVK 523
Cdd:PRK03918  299 SEFYEEYLDELREIEKRLSRLEEEINGIEERI-----KELEEKEERLEELKKKL----KELEKRLEE-LEERHELYEEAK 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   524 YLNEQIATLQSELvsKDEALEKFslsecgienlrrelellkEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATS 603
Cdd:PRK03918  369 AKKEELERLKKRL--TGLTPEKL------------------EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAI 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   604 DSLESERvnktDECEILQTEvrMRDEQIRELnqqLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKtEKELVQS 683
Cdd:PRK03918  429 EELKKAK----GKCPVCGRE--LTEEHRKEL---LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKL 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   684 KEQAAKTLNDKEQLEK-QISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKqNELEDFQKKQSESEVHLQEIKA 762
Cdd:PRK03918  499 KELAEQLKELEEKLKKyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK-KKLAELEKKLDELEEELAELLK 577

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   763 QNTQKDFELVESGES-LKKLQ----QQLEQKTLGHEkLQAALEELKKEKETiIKEKEQELQQLQSKSAESESALKVVQVQ 837
Cdd:PRK03918  578 ELEELGFESVEELEErLKELEpfynEYLELKDAEKE-LEREEKELKKLEEE-LDKAFEELAETEKRLEELRKELEELEKK 655

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   838 -LEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANgSLEEEAKKSGHLLEQITKLK 916
Cdd:PRK03918  656 ySEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE-KLEKALERVEELREKVKKYK 734


                  ....*
gi 24584806   917 SEVGE 921
Cdd:PRK03918  735 ALLKE 739
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 629-832 3.44e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.47  E-value: 3.44e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  629 EQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQisdlkqLA 708
Cdd:COG4942   27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE------LE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  709 EQEKLVREMtenaINQIQLEKESIEQQLALKQNELEDFQKKQSesevHLQEIKAQNTQKDFELVESGESLKKLQQQLEQK 788
Cdd:COG4942  101 AQKEELAEL----LRALYRLGRQPPLALLLSPEDFLDAVRRLQ----YLKYLAPARREQAEELRADLAELAALRAELEAE 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 24584806  789 TLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALK 832
Cdd:COG4942  173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA 216
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1060-1550 4.50e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 58.31  E-value: 4.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1060 LQEEVTKAKTENLELST------GTQTTIKDLQERLEITNAELqhKEKMASEDAQkiadlktlveaiqvANANISATNAE 1133
Cdd:pfam12128  246 LQQEFNTLESAELRLSHlhfgykSDETLIASRQEERQETSAEL--NQLLRTLDDQ--------------WKEKRDELNGE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1134 LSTVLEVLQAEKSEtnhiFELFEMEADMNSERLIEKVTGIKEelkethlQLDERQKKFEELEEKLKQAQQSEQKLQQESQ 1213
Cdd:pfam12128  310 LSAADAAVAKDRSE----LEALEDQHGAFLDADIETAAADQE-------QLPSWQSELENLEERLKALTGKHQDVTAKYN 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1214 TSKEKLteiqqSLQELQDSVKQKEELVQNLEEKVR---ESSSIIEAQNTKLNEsnvqlenktsclkETQDQLLESQKKEK 1290
Cdd:pfam12128  379 RRRSKI-----KEQNNRDIAGIKDKLAKIREARDRqlaVAEDDLQALESELRE-------------QLEAGKLEFNEEEY 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1291 QLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQqatnKELQELLVKSQENEGNLQGESLAVT 1370
Cdd:pfam12128  441 RLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQ----SELRQARKRRDQASEALRQASRRLE 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1371 EKLQQLEQAN-------GELKEALCQKENGLKELQGKL---------------------DESN---TVLESQKKSHNEIQ 1419
Cdd:pfam12128  517 ERQSALDELElqlfpqaGTLLHFLRKEAPDWEQSIGKVispellhrtdldpevwdgsvgGELNlygVKLDLKRIDVPEWA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1420 DKLEQAQQK----ERTLQEETSKLAEQLSQLKQANEELQKS---------------LQQKQLLLEKGNEFDT---QLAEY 1477
Cdd:pfam12128  597 ASEEELRERldkaEEALQSAREKQAAAEEQLVQANGELEKAsreetfartalknarLDLRRLFDEKQSEKDKknkALAER 676

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806   1478 QK-VIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRR-QLESLELEKSREVLSLKAQMNG 1550
Cdd:pfam12128  677 KDsANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDaQLALLKAAIAARRSGAKAELKA 751
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1046-1505 4.99e-08

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 58.17  E-value: 4.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1046 GERKE-KSFEESIKNLQEEVTKAKT-----------ENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQK-IAD 1112
Cdd:COG5022  807 GSRKEyRSYLACIIKLQKTIKREKKlreteevefslKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERqLQE 886

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1113 LKTLVEAIQvanaNISATNAEL-STVLEVLQAEKS----ETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDER 1187
Cdd:COG5022  887 LKIDVKSIS----SLKLVNLELeSEIIELKKSLSSdlieNLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEV 962

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1188 QKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESnvq 1267
Cdd:COG5022  963 ESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSES--- 1039

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1268 leNKTSCLKETQDQLLESQKKEKQLQEEAAKLsgelqQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKE 1347
Cdd:COG5022 1040 --TELSILKPLQKLKGLLLLENNQLQARYKAL-----KLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPA 1112

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1348 -LQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEAlcqkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQA- 1425
Cdd:COG5022 1113 nVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVL-------QLELDGLFWEANLEALPSPPPFAALSEKRLYQs 1185

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1426 ---QQKERTLQEETSKLAEQLSQL-KQANEELQKSLQQKQLLLEK--GNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQ 1499
Cdd:COG5022 1186 alyDEKSKLSSSEVNDLKNELIALfSKIFSGWPRGDKLKKLISEGwvPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLL 1265


                 ....*.
gi 24584806 1500 NRVAEL 1505
Cdd:COG5022 1266 NSIDNL 1271
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1050-1554 5.77e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 5.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1050 EKSFEESIKNLQEEVtkaktENLElstGTQTTIKDLQERLEITNAELQHKEKMAsEDAQKIADLKTLVEAIQVANANISA 1129
Cdd:COG4913  220 EPDTFEAADALVEHF-----DDLE---RAHEALEDAREQIELLEPIRELAERYA-AARERLAELEYLRAALRLWFAQRRL 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1130 tnAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIE-----------KVTGIKEELKETHLQLDERQKKFEELEEKL 1198
Cdd:COG4913  291 --ELLEAELEELRAELARLEAELERLEARLDALREELDEleaqirgnggdRLEQLEREIERLERELEERERRRARLEALL 368

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1199 KQAQQSE-------QKLQQESQTSKEKLTEIQQSLQELQDSVKQKEelvQNLEEKVRESSSIIEAqntklnesnvqLENK 1271
Cdd:COG4913  369 AALGLPLpasaeefAALRAEAAALLEALEEELEALEEALAEAEAAL---RDLRRELRELEAEIAS-----------LERR 434

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1272 TSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDS------------LV------KVEELV--------- 1324
Cdd:COG4913  435 KSNIPARLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAiervlggfaltlLVppehyaAALRWVnrlhlrgrl 514

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1325 ---KVLEEKLQAATSQLDAQQATNK----------ELQELLVKSQ-----ENEGNLQGESLAVTEKLQ------------ 1374
Cdd:COG4913  515 vyeRVRTGLPDPERPRLDPDSLAGKldfkphpfraWLEAELGRRFdyvcvDSPEELRRHPRAITRAGQvkgngtrhekdd 594

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1375 --------QLEQANGELKEALcQKEngLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKE---------RTLQEETS 1437
Cdd:COG4913  595 rrrirsryVLGFDNRAKLAAL-EAE--LAELEEELAEAEERLEALEAELDALQERREALQRLAeyswdeidvASAEREIA 671

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1438 KLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQK 1517
Cdd:COG4913  672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                        570       580       590
                 ....*....|....*....|....*....|....*..
gi 24584806 1518 TAYLETKELRRQLESLELEKSREVLSLKAQMNGASSR 1554
Cdd:COG4913  752 EERFAAALGDAVERELRENLEERIDALRARLNRAEEE 788
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1176-1386 5.93e-08

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 56.76  E-value: 5.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1176 ELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIE 1255
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1256 AQNTKLNESNVQLENKT-----------SCLKETQDQLLESQKKEK-QLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1323
Cdd:COG3883   97 RSGGSVSYLDVLLGSESfsdfldrlsalSKIADADADLLEELKADKaELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806 1324 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEA 1386
Cdd:COG3883  177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 239
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
900-1522 9.99e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 9.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  900 EEAKKSGHLLEQITKLKSEVGETQAALSSCHT-----DVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDT 974
Cdd:COG4913  245 EDAREQIELLEPIRELAERYAAARERLAELEYlraalRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREE 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  975 LhAELQAERSSSsalhtklskfsdeiatGHKELtskaDAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFE 1054
Cdd:COG4913  325 L-DELEAQIRGN----------------GGDRL----EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFA 383

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1055 ESIKNLQEEVTKAKTE---NLELSTGTQTTIKDLQERLEITNAELQH---------------KEKMASEDAQKIADLKTL 1116
Cdd:COG4913  384 ALRAEAAALLEALEEEleaLEEALAEAEAALRDLRRELRELEAEIASlerrksniparllalRDALAEALGLDEAELPFV 463

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1117 VEAIQVANANISATNA-E----------------LSTVLEVLQAEKSETNHIFELFE--------MEADMNSerLIEKVT 1171
Cdd:COG4913  464 GELIEVRPEEERWRGAiErvlggfaltllvppehYAAALRWVNRLHLRGRLVYERVRtglpdperPRLDPDS--LAGKLD 541

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1172 gIK------------------------EELKE---------------THLQLDERQKKFEEL------EEKLKQAQQSEQ 1206
Cdd:COG4913  542 -FKphpfrawleaelgrrfdyvcvdspEELRRhpraitragqvkgngTRHEKDDRRRIRSRYvlgfdnRAKLAALEAELA 620

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1207 KLQQESQTSKEKLTEIQQSLQELQdsvkQKEELVQNLEEKVRESSSIIEAQnTKLNESNVQLENktscLKETQDQLLESQ 1286
Cdd:COG4913  621 ELEEELAEAEERLEALEAELDALQ----ERREALQRLAEYSWDEIDVASAE-REIAELEAELER----LDASSDDLAALE 691

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1287 KKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATN--KELQELLVKSQENE--GNL 1362
Cdd:COG4913  692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleERFAAALGDAVERElrENL 771

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1363 QGESLAVTEKLQQLEQANGELKEALCQK-ENGLKELQGKLDEsntvLESQKKSHNEIQ-DKLEQAQQKERTLQEETS--K 1438
Cdd:COG4913  772 EERIDALRARLNRAEEELERAMRAFNREwPAETADLDADLES----LPEYLALLDRLEeDGLPEYEERFKELLNENSieF 847

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1439 LAEQLSQLKQANEE-------LQKSLQQKQ------LLLEKGNEFDTQLAEYQKVIDEMDDAASVKSA-LLEQLQNRVAE 1504
Cdd:COG4913  848 VADLLSKLRRAIREikeridpLNDSLKRIPfgpgryLRLEARPRPDPEVREFRQELRAVTSGASLFDEeLSEARFAALKR 927

                        730
                 ....*....|....*...
gi 24584806 1505 LETALRQANDAQKTAYLE 1522
Cdd:COG4913  928 LIERLRSEEEESDRRWRA 945
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1167-1560 1.25e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 1.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1167 IEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESqtskEKLTEIQQSLQELQDSVKQKEELVQNLEEK 1246
Cdd:pfam02463  144 IEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELI----IDLEELKLQELKLKEQAKKALEYYQLKEKL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1247 VRESSSIIEAQNTKLNESNvqlenktscLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKV 1326
Cdd:pfam02463  220 ELEEEYLLYLDYLKLNEER---------IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKL 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1327 LEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNT 1406
Cdd:pfam02463  291 LAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1407 VLESQKKSHNEIQDKLEQAQ---QKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1483
Cdd:pfam02463  371 LEEELLAKKKLESERLSSAAklkEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEK 450

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806   1484 mddAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAqMNGASSRSGKGDE 1560
Cdd:pfam02463  451 ---EELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLK-VLLALIKDGVGGR 523
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1042-1547 1.56e-07

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 56.29  E-value: 1.56e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1042 LKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQttikDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQ 1121
Cdd:pfam05557   14 LQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQ----ELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1122 VANANISATNAELSTVLEVLQAEKSETNHIFelfeMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQA 1201
Cdd:pfam05557   90 KKLNEKESQLADAREVISCLKNELSELRRQI----QRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSL 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1202 QQSEQKLQQESQ--TSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEaQNTKLNESNVQLENKTSCLKETQ 1279
Cdd:pfam05557  166 AEAEQRIKELEFeiQSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIE-NKLLLKEEVEDLKRKLEREEKYR 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1280 DQL----LESQKKEKQLQE-------------EAAKLSGELQQVQ-------EANGDIKDSLVKVEELVKVLEEKLQAAT 1335
Cdd:pfam05557  245 EEAatleLEKEKLEQELQSwvklaqdtglnlrSPEDLSRRIEQLQqreivlkEENSSLTSSARQLEKARRELEQELAQYL 324

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1336 SQLDAQQATNKELQELLVKSQE------NEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN---T 1406
Cdd:pfam05557  325 KKIEDLNKKLKRHKALVRRLQRrvllltKERDGYRAILESYDKELTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEaqlS 404

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1407 VLESQKKSHNEIQDKLEQAQQ--KERTLQEETSKLAEQLSQLKQANEELQkslQQKQLLLEKGNEFDTQLA--EYQKVID 1482
Cdd:pfam05557  405 VAEEELGGYKQQAQTLERELQalRQQESLADPSYSKEEVDSLRRKLETLE---LERQRLREQKNELEMELErrCLQGDYD 481

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1483 E------------MDDAASVKSALLEQLQNRV-----------AELETALRQANDAQKTAYLETKELRRQLESLEL--EK 1537
Cdd:pfam05557  482 PkktkvlhlsmnpAAEAYQQRKNQLEKLQAEIerlkrllkkleDDLEQVLRLPETTSTMNFKEVLDLRKELESAELknQR 561

                          570
                   ....*....|
gi 24584806   1538 SREVLSLKAQ 1547
Cdd:pfam05557  562 LKEVFQAKIQ 571
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
737-1227 1.69e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 1.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  737 ALKQNELEDFQKKQSESEVHLQEIKAQNTQKDfELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKE-- 814
Cdd:COG4717   50 RLEKEADELFKPQGRKPELNLKELKELEEELK-EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQll 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  815 ---QELQQLQSKSAESESALKVVqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQSELKstqsnlEAKSKQL 891
Cdd:COG4717  129 plyQELEALEAELAELPERLEEL---------------EERLEELRELEEELEELEAELAELQEELE------ELLEQLS 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  892 EAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAlEKVNKEYAESRAEAS--DLQDKVK 969
Cdd:COG4717  188 LATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-ERLKEARLLLLIAAAllALLGLGG 266

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  970 EITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAegerk 1049
Cdd:COG4717  267 SLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLE----- 341

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1050 eksFEESIKNLQEEVTKAKTENLELstgtqttikdLQERLEITNAELQHKEKMASED-----AQKIADLKTLVEAIQVAN 1124
Cdd:COG4717  342 ---LLDRIEELQELLREAEELEEEL----------QLEELEQEIAALLAEAGVEDEEelraaLEQAEEYQELKEELEELE 408

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1125 ANISATNAELSTVLEVLQAEKSETnhifELFEMEADMNS-----ERLIEKVTGIKEELK--ETHLQLDERQKKFEELEEK 1197
Cdd:COG4717  409 EQLEELLGELEELLEALDEEELEE----ELEELEEELEEleeelEELREELAELEAELEqlEEDGELAELLQELEELKAE 484

                        490       500       510
                 ....*....|....*....|....*....|
gi 24584806 1198 LKQAQQSEQKLQQESQTSKEKLTEIQQSLQ 1227
Cdd:COG4717  485 LRELAEEWAALKLALELLEEAREEYREERL 514
PRK11281 PRK11281
mechanosensitive channel MscK;
1276-1519 2.03e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 56.07  E-value: 2.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1276 KETQDQLlESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLE---EKLQAATSQLDAQQATNKElqell 1352
Cdd:PRK11281   39 ADVQAQL-DALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAqapAKLRQAQAELEALKDDNDE----- 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1353 VKSQENEgnlqgeslavTEKLQQLEQangelkeALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKertL 1432
Cdd:PRK11281  113 ETRETLS----------TLSLRQLES-------RLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQR---L 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1433 QEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAE--------YQKVIDEMddaaSVKSALLEQ----LQN 1500
Cdd:PRK11281  173 QQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSLEgntqlqdlLQKQRDYL----TARIQRLEHqlqlLQE 248

                         250       260
                  ....*....|....*....|....
gi 24584806  1501 -----RVAELETALRQANDAQKTA 1519
Cdd:PRK11281  249 ainskRLTLSEKTVQEAQSQDEAA 272
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
669-1143 2.22e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 2.22e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  669 KSTLLEKTEKELVQSKEQAAKTLNdKEQLEKQISDLKQLAEQEKLVREMTEN--AINQIQLEKESIEQQLALKQNELEDF 746
Cdd:COG4717   36 KSTLLAFIRAMLLERLEKEADELF-KPQGRKPELNLKELKELEEELKEAEEKeeEYAELQEELEELEEELEELEAELEEL 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  747 QKKQSESEVHLQeikaqntqkdfeLVESGESLKKLQQQLEQktlghekLQAALEELKkeketiikEKEQELQQLQSKSAE 826
Cdd:COG4717  115 REELEKLEKLLQ------------LLPLYQELEALEAELAE-------LPERLEELE--------ERLEELRELEEELEE 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  827 SESALKVVQVQLEQLQQQAAASGEEgskTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKsg 906
Cdd:COG4717  168 LEAELAELQEELEELLEQLSLATEE---ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-- 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  907 hllEQITKLKS--EVGETQAALSSCHTDVESKTKQLEAANAAL----------EKVNKEYAESRAEASDLQDKVKEITDT 974
Cdd:COG4717  243 ---ERLKEARLllLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllallfllLAREKASLGKEAEELQALPALEELEEE 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  975 LHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQK--EKELQELRQQLQDSQDSQTKLKAEGERKEKS 1052
Cdd:COG4717  320 ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEelEQEIAALLAEAGVEDEEELRAALEQAEEYQE 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1053 FEESIKNLQEEVTKAKTENLELSTGTQTTikDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQvANANISATNA 1132
Cdd:COG4717  400 LKEELEELEEQLEELLGELEELLEALDEE--ELEEELEELEEELEELEEELEELREELAELEAELEQLE-EDGELAELLQ 476

                        490
                 ....*....|.
gi 24584806 1133 ELSTVLEVLQA 1143
Cdd:COG4717  477 ELEELKAELRE 487
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1007-1265 2.51e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 2.51e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1007 LTSKADAWSQEMLQKEKELQELRQQLQDSQdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQ 1086
Cdd:COG4942   11 LALAAAAQADAAAEAEAELEQLQQEIAELE----KELAALKKEEKALLKQLAALERRIAALARRIRAL----EQELAALE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1087 ERLEITNAELQHKEKmaSEDAQKiADLKTLVEAIQvananisaTNAELSTVLEVLQAEKSetNHIFELFEMEADMNSERl 1166
Cdd:COG4942   83 AELAELEKEIAELRA--ELEAQK-EELAELLRALY--------RLGRQPPLALLLSPEDF--LDAVRRLQYLKYLAPAR- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1167 IEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEK 1246
Cdd:COG4942  149 REQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228

                        250
                 ....*....|....*....
gi 24584806 1247 VRESSSIIEAQNTKLNESN 1265
Cdd:COG4942  229 IARLEAEAAAAAERTPAAG 247
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 853-1077 3.27e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.38  E-value: 3.27e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  853 SKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTD 932
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  933 VESKTKQLEAANAALEKVNKEY-------AESRAEASDLQDKVKEITDTLHA---ELQAERSSSSALHTKLSKFSDEIAT 1002
Cdd:COG4942   99 LEAQKEELAELLRALYRLGRQPplalllsPEDFLDAVRRLQYLKYLAPARREqaeELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806 1003 GHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTG 1077
Cdd:COG4942  179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1141-1511 3.45e-07

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 54.90  E-value: 3.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1141 LQAEKSETNHIFELFEMeADMNSERLIEKVTGIKEELKETHLQLDERqkkFEELEEKLKQAQQSEQKLQQESQTSKEKLT 1220
Cdd:pfam07888   36 LEECLQERAELLQAQEA-ANRQREKEKERYKRDREQWERQRRELESR---VAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1221 EIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLS 1300
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1301 GELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKEL---QELLVKSQENEGNLqGESLAVTEKLQQLE 1377
Cdd:pfam07888  192 KEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELrslQERLNASERKVEGL-GEELSSMAAQRDRT 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1378 QAngELKEALCQkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERtlqeetSKLAEQLSQLKQANEELQKSL 1457
Cdd:pfam07888  271 QA--ELHQARLQ----AAQLTLQLADASLALREGRARWAQERETLQQSAEADK------DRIEKLSAELQRLEERLQEER 338

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806   1458 QQKQLL-LEKGNEFD---TQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQ 1511
Cdd:pfam07888  339 MEREKLeVELGREKDcnrVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQ 396
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 487-770 3.86e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.13  E-value: 3.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    487 QEEIAKLQEKMTIQQKevesRIAEQLEEEQRLRENVKYLNEQIATLqselVSKDEALEKFSLSECGIENLRRELELLKEE 566
Cdd:pfam17380  332 QAAIYAEQERMAMERE----RELERIRQEERKRELERIRQEEIAME----ISRMRELERLQMERQQKNERVRQELEAARK 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    567 NEKQAQEAQaeftRKLAEKSVEVLRLSSELQNLKATS-DSLESERVNktdECEILQTEVRMRDEQIRELNQQLDEvttql 645
Cdd:pfam17380  404 VKILEEERQ----RKIQQQKVEMEQIRAEQEEARQREvRRLEEERAR---EMERVRLEEQERQQQVERLRQQEEE----- 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    646 nvQKADSSALDDMLRLQKEGTEEKSTLLEKtekELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI 725
Cdd:pfam17380  472 --RKRKKLELEKEKRDRKRAEEQRRKILEK---ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQ 546

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 24584806    726 QL-EKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFE 770
Cdd:pfam17380  547 EMeERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 1154-1484 4.81e-07

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 54.47  E-value: 4.81e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1154 LFEMEADMNSERLIEkvtgIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQE----L 1229
Cdd:pfam06160   69 LFEAEELNDKYRFKK----AKKALDEIEELLDDIEEDIKQILEELDELLESEEKNREEVEELKDKYRELRKTLLAnrfsY 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1230 QDSVKQKEELVQNLEEK------VRESSSIIEAQNT--KLNESNVQLENKTS--------CLKETQDQLLESQKKEKQLQ 1293
Cdd:pfam06160  145 GPAIDELEKQLAEIEEEfsqfeeLTESGDYLEAREVleKLEEETDALEELMEdipplyeeLKTELPDQLEELKEGYREME 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1294 E-----EAAKLSGELQQVQEangDIKDSLVKVEEL-VKVLEEKLQAATSQLDAqqatnkeLQELLVKSQENEGNLQGESL 1367
Cdd:pfam06160  225 EegyalEHLNVDKEIQQLEE---QLEENLALLENLeLDEAEEALEEIEERIDQ-------LYDLLEKEVDAKKYVEKNLP 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1368 AVTEKLQQLEQANGELKE--ALCQKENGL--KELQgKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL 1443
Cdd:pfam06160  295 EIEDYLEHAEEQNKELKEelERVQQSYTLneNELE-RVRGLEKQLEELEKRYDEIVERLEEKEVAYSELQEELEEILEQL 373

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 24584806   1444 SQLKQANEELQKSLQQkqllLEKGnEFDTQ--LAEYQKVIDEM 1484
Cdd:pfam06160  374 EEIEEEQEEFKESLQS----LRKD-ELEARekLDEFKLELREI 411
PRK12704 PRK12704
phosphodiesterase; Provisional
 1140-1299 7.05e-07

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 54.01  E-value: 7.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1140 VLQAEKsETNHIFELFEMEADMNSErliEKVTGIKEELK----ETHLQLDERQKKFEELEEKLkqaQQSEQKLQQESqts 1215
Cdd:PRK12704   33 IKEAEE-EAKRILEEAKKEAEAIKK---EALLEAKEEIHklrnEFEKELRERRNELQKLEKRL---LQKEENLDRKL--- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1216 kEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssIIEAQNTKLNE-SNVQLEnktsclkETQDQLLESQKKEkqLQE 1294
Cdd:PRK12704  103 -ELLEKREEELEKKEKELEQKQQELEKKEEELEE---LIEEQLQELERiSGLTAE-------EAKEILLEKVEEE--ARH 169


                  ....*
gi 24584806  1295 EAAKL 1299
Cdd:PRK12704  170 EAAVL 174
PRK12704 PRK12704
phosphodiesterase; Provisional
 694-826 7.36e-07

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 54.01  E-value: 7.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   694 KEQLEKQISDLKQLAEQeklvremtenAINQIQLEKESIEQQLALKQNELEDFQKKQSESEV-----HLQEIKAQNTQKD 768
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKR----------ILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELrerrnELQKLEKRLLQKE 95

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806   769 FELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAE 826
Cdd:PRK12704   96 ENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAE 153
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1023-1470 7.59e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 7.59e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1023 KELQELRQQLQDSQDSQTKLKAEGERKEKSfEESIKNLQEEVTKAKTENLELSTGTQttIKDLQERLEITNAELQHKEKM 1102
Cdd:COG4717   71 KELKELEEELKEAEEKEEEYAELQEELEEL-EEELEELEAELEELREELEKLEKLLQ--LLPLYQELEALEAELAELPER 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1103 ASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETnhifelfemeadmnSERLIEKVTGIKEELKETHL 1182
Cdd:COG4717  148 LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEE--------------LQDLAEELEELQQRLAELEE 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1183 QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQS-LQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKL 1261
Cdd:COG4717  214 ELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLL 293

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1262 NESNVQLENKT------SCLKETQDQLLESQKKEKQLQ-----EEAAKLSGELQQVQEANGDIKD-----SLVKVEELVK 1325
Cdd:COG4717  294 AREKASLGKEAeelqalPALEELEEEELEELLAALGLPpdlspEELLELLDRIEELQELLREAEEleeelQLEELEQEIA 373

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1326 VL--------EEKLQAATSQLDAQQATNKELQELlvKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKEL 1397
Cdd:COG4717  374 ALlaeagvedEEELRAALEQAEEYQELKEELEEL--EEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEEL 451

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806 1398 QGKLDESNTVLESQKKShneiqDKLEQAQQKERTLQEETSKLAEQ---LSQLKQANEELQKSLQQKQL--LLEKGNEF 1470
Cdd:COG4717  452 REELAELEAELEQLEED-----GELAELLQELEELKAELRELAEEwaaLKLALELLEEAREEYREERLppVLERASEY 524
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1183-1505 8.42e-07

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 54.29  E-value: 8.42e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1183 QLDERQkkfeeLEEKLKQAQQSEQKLQQES----QTSKEKLTEIQQSL---QELQDSVKQKEELVQNLEEKVRESSSiiE 1255
Cdd:PRK10929   22 APDEKQ-----ITQELEQAKAAKTPAQAEIvealQSALNWLEERKGSLeraKQYQQVIDNFPKLSAELRQQLNNERD--E 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1256 AQNTKLNESNVQLENKtscLKETQDQLLEsqkkekqlqeeaakLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAAT 1335
Cdd:PRK10929   95 PRSVPPNMSTDALEQE---ILQVSSQLLE--------------KSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1336 SQLDAQQATNKELQELLVKSqenegnLQGESLAVTEKLQQLE---------QANGELKEALCQKENglKELQGKLDESNT 1406
Cdd:PRK10929  158 RRLQTLGTPNTPLAQAQLTA------LQAESAALKALVDELElaqlsannrQELARLRSELAKKRS--QQLDAYLQALRN 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1407 VLESQKkshneiQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSL-QQKQLLLEKGNEFDTQLAEYQKV----- 1480
Cdd:PRK10929  230 QLNSQR------QREAERALESTELLAEQSGDLPKSIVAQFKINRELSQALnQQAQRMDLIASQQRQAASQTLQVrqaln 303

                         330       340
                  ....*....|....*....|....*.
gi 24584806  1481 -IDEMDDAASVKSALLEQLQNRVAEL 1505
Cdd:PRK10929  304 tLREQSQWLGVSNALGEALRAQVARL 329
46 PHA02562
endonuclease subunit; Provisional
 1106-1322 1.16e-06

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 53.48  E-value: 1.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1106 DAQKIADLKTLVEA-IQVANANISATNAELSTVLEVLqaeKSETNHIFELfEMEADMNSERLIEKVTGIKEELKETHLQL 1184
Cdd:PHA02562  161 DISVLSEMDKLNKDkIRELNQQIQTLDMKIDHIQQQI---KTYNKNIEEQ-RKKNGENIARKQNKYDELVEEAKTIKAEI 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1185 DERQKKFEELEE----------KLKQAQ-------QSEQKL--------------QQESQTsKEKLTEIQQSLQELQDSV 1233
Cdd:PHA02562  237 EELTDELLNLVMdiedpsaalnKLNTAAakikskiEQFQKVikmyekggvcptctQQISEG-PDRITKIKDKLKELQHSL 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1234 KQKEELVQNLEEKVREsssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDI 1313
Cdd:PHA02562  316 EKLDTAIDELEEIMDE----FNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKI 391


                  ....*....
gi 24584806  1314 KDSLVKVEE 1322
Cdd:PHA02562  392 VKTKSELVK 400
46 PHA02562
endonuclease subunit; Provisional
 703-975 1.16e-06

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 53.48  E-value: 1.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   703 DLKQLAEQEKL----VREMTENaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAqntqkdfELVESGESL 778
Cdd:PHA02562  161 DISVLSEMDKLnkdkIRELNQQ-IQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYD-------ELVEEAKTI 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   779 KklqQQLEQktlghekLQAALEELKKEKEtiikEKEQELQQLQSKSAESESALKvvqvqleqlqqqaaasgeegskTVAK 858
Cdd:PHA02562  233 K---AEIEE-------LTDELLNLVMDIE----DPSAALNKLNTAAAKIKSKIE----------------------QFQK 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   859 L------HDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKsevgETQAALSSCHTD 932
Cdd:PHA02562  277 VikmyekGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLL----ELKNKISTNKQS 352

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 24584806   933 VESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTL 975
Cdd:PHA02562  353 LITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTK 395
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1668-1684 1.31e-06

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 45.92  E-value: 1.31e-06
                           10
                   ....*....|....*..
gi 24584806   1668 RKYCDSCEVFGHDTSEC 1684
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1175-1462 1.32e-06

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 52.22  E-value: 1.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1175 EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1254
Cdd:COG1340    1 SKTDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEER 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1255 EAQNTKLNESNVQLENktscLKETQDQLLESQKKEKQLQEEAAKLSGElQQVQEANGDIKDSLVkveELVKVLEEKLQAA 1334
Cdd:COG1340   81 DELNEKLNELREELDE----LRKELAELNKAGGSIDKLRKEIERLEWR-QQTEVLSPEEEKELV---EKIKELEKELEKA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1335 TSQLDAqqatNKELQELLvksqenegnlqGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS 1414
Cdd:COG1340  153 KKALEK----NEKLKELR-----------AELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKE 217

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 24584806 1415 HNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQL 1462
Cdd:COG1340  218 IVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEEL 265
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 868-1094 1.35e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 1.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  868 SQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAL 947
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  948 EKVNKEYAEsRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQE 1027
Cdd:COG4942  100 EAQKEELAE-LLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806 1028 LRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNA 1094
Cdd:COG4942  179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 661-1456 1.38e-06

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 53.68  E-value: 1.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   661 LQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLaeqeklvremtENAINQIQLEKESIEQQLALKQ 740
Cdd:PTZ00440  839 LQKFPTEDENLNLKELEKEFNENNQIVDNIIKDIENMNKNINIIKTL-----------NIAINRSNSNKQLVEHLLNNKI 907

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   741 NELEDFQKkqsesevHLQEIKAQN----TQKDFELVESGESLKKLQQQLEQKTLGHEKLQA--ALEELKKEKETIIKEKE 814
Cdd:PTZ00440  908 DLKNKLEQ-------HMKIINTDNiiqkNEKLNLLNNLNKEKEKIEKQLSDTKINNLKMQIekTLEYYDKSKENINGNDG 980

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   815 QELQQLQSKSAESEsALKVVQVQLEQLQQQAAASGEEgskTVAKLHDEISQLksqaeeTQSELKSTQSNLEAKSKQLEAa 894
Cdd:PTZ00440  981 THLEKLDKEKDEWE-HFKSEIDKLNVNYNILNKKIDD---LIKKQHDDIIEL------IDKLIKEKGKEIEEKVDQYIS- 1049

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   895 ngSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEItdt 974
Cdd:PTZ00440 1050 --LLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALLKKIDENKNKLIEIKNKSHEHVVNADKEKNKQTEH--- 1124

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   975 lhaeLQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFE 1054
Cdd:PTZ00440 1125 ----YNKKKKSLEKIYKQMEKTLKELENMNLEDITLNEVNEIEIEYERILIDHIVEQINNEAKKSKTIMEEIESYKKDID 1200

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1055 ESIKNLQEEvTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKmaSEDAQKIADLKT--------LVEAIQVANAn 1126
Cdd:PTZ00440 1201 QVKKNMSKE-RNDHLTTFEYNAYYDKATASYENIEELTTEAKGLKGE--ANRSTNVDELKEiklqvfsyLQQVIKENNK- 1276

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1127 ISATNAELSTVLEVLQAEKSET------NHIFELFEMEADMNSErlIEKVTGIKEELKETHLQLDERQKKFEELEEKlKQ 1200
Cdd:PTZ00440 1277 MENALHEIKNMYEFLISIDSEKilkeilNSTKKAEEFSNDAKKE--LEKTDNLIKQVEAKIEQAKEHKNKIYGSLED-KQ 1353

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1201 AQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEE-KVRESSSIIEAQNTKLNESNVQLENKTSCLKETQ 1279
Cdd:PTZ00440 1354 IDDEIKKIEQIKEEISNKRKEINKYLSNIKSNKEKCDLHVRNASRgKDKIDFLNKHEAIEPSNSKEVNIIKITDNINKCK 1433

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1280 DQLLESQKKEKQLQEEAAKLsgeLQQVQEANGDIKDSLVKVEElvKVLEEKLQAATSQLDAQQATNKELQELLVKSQENE 1359
Cdd:PTZ00440 1434 QYSNEAMETENKADENNDSI---IKYEKEITNILNNSSILGKK--TKLEKKKKEATNIMDDINGEHSIIKTKLTKSSEKL 1508

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1360 GNLQ--------GESLA---VTEKLQQLEQANGELKEALCQKENGLKELQ----------------GKLDESNTvLESQK 1412
Cdd:PTZ00440 1509 NQLNeqpnikreGDVLNndkSTIAYETIQYNLGRVKHNLLNILNIKDEIEtilnkaqdlmrdiskiSKIVENKN-LENLN 1587

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....
gi 24584806  1413 KSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKS 1456
Cdd:PTZ00440 1588 DKEADYVKYLDNILKEKQLMEAEYKKLNEIYSDVDNIEKELKKH 1631
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
508-755 1.57e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.10  E-value: 1.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  508 IAEQLEEEQ-RLRENVKYLNEQIATLQSELVSKDEALEKFslsecgienlrrelelLKEENEKQAQEAQAEFTRKLAEKS 586
Cdd:COG3206  162 LEQNLELRReEARKALEFLEEQLPELRKELEEAEAALEEF----------------RQKNGLVDLSEEAKLLLQQLSELE 225

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  587 VEVLRLSSELQNLKATSDSLESERVNKTDECEILQTevrmrDEQIRELNQQLDEVTTQLNVQKADSSALD-DMLRLQKEG 665
Cdd:COG3206  226 SQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNHpDVIALRAQI 300

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  666 TEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvremtenaINQIQLEKESIEQQLALKQNELED 745
Cdd:COG3206  301 AALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAE-----------LPELEAELRRLEREVEVARELYES 369

                        250
                 ....*....|
gi 24584806  746 FQKKQSESEV 755
Cdd:COG3206  370 LLQRLEEARL 379
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1194-1429 1.64e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.10  E-value: 1.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1194 LEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELqdsvKQKEELVqNLEEKVRESSSIIEAQNTKLNESNVQLENKTS 1273
Cdd:COG3206  166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEF----RQKNGLV-DLSEEAKLLLQQLSELESQLAEARAELAEAEA 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1274 CLKETQDQLLESQKKEKQLQEEAAkLSGELQQVQEANGDIKDSLVKVEE---LVKVLEEKLQAATSQLDAqqatnkELQE 1350
Cdd:COG3206  241 RLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPnhpDVIALRAQIAALRAQLQQ------EAQR 313

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806 1351 LLVksqenegNLQGESLAVTEKLQQLEQANGELKEALcqkeNGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKE 1429
Cdd:COG3206  314 ILA-------SLEAELEALQAREASLQAQLAQLEARL----AELPELEAELRRLEREVEVARELYESLLQRLEEARLAE 381
PRK11281 PRK11281
mechanosensitive channel MscK;
414-824 2.26e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.61  E-value: 2.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   414 ELESALD--NERKKTEE----LQCSIDEAQfcgdELNAQSQVYKEKIHDLESKITKlvsATPSLQSIlppdlpsddgalQ 487
Cdd:PRK11281   40 DVQAQLDalNKQKLLEAedklVQQDLEQTL----ALLDKIDRQKEETEQLKQQLAQ---APAKLRQA------------Q 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   488 EEIAKLQEKM---------TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSelvskdealekfslsecgienlrr 558
Cdd:PRK11281  101 AELEALKDDNdeetretlsTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQT------------------------ 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   559 elellkeenekQAQEAQAEftrkLAEKSVEVLRLSSELQNLKATSDSLESERVNKtdeceiLQTEVRMRDEQIrELNQQL 638
Cdd:PRK11281  157 -----------QPERAQAA----LYANSQRLQQIRNLLKGGKVGGKALRPSQRVL------LQAEQALLNAQN-DLQRKS 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   639 DEVTTQLNvqkadssaldDMLRLQKEGTEEKSTLLEKT---------EKELVQSKEQAAKTLNDKE------------QL 697
Cdd:PRK11281  215 LEGNTQLQ----------DLLQKQRDYLTARIQRLEHQlqllqeainSKRLTLSEKTVQEAQSQDEaariqanplvaqEL 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   698 E--KQISD--------LKQLAEQEKLVREMTENAINQIQLEKESI--------------EQQLALKQNEL-EDFQKKQSE 752
Cdd:PRK11281  285 EinLQLSQrllkatekLNTLTQQNLRVKNWLDRLTQSERNIKEQIsvlkgslllsrilyQQQQALPSADLiEGLADRIAD 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   753 SEVHLQEIkaqNTQKDfELVESGESLKKLQQQleQKTLGHEKLQAALEELKKEKETIIKEKEQEL--------------Q 818
Cdd:PRK11281  365 LRLEQFEI---NQQRD-ALFQPDAYIDKLEAG--HKSEVTDEVRDALLQLLDERRELLDQLNKQLnnqlnlainlqlnqQ 438


                  ....*.
gi 24584806   819 QLQSKS 824
Cdd:PRK11281  439 QLLSVS 444
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 464-712 2.46e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 2.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  464 LVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMtiqqKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEAL 543
Cdd:COG4942   10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  544 EKFSLSEcgienlrrelellkeeneKQAQEAQAEFTRKLAEKSVEVLRLS--SELQNLKATSDSLESERVNktdecEILQ 621
Cdd:COG4942   86 AELEKEI------------------AELRAELEAQKEELAELLRALYRLGrqPPLALLLSPEDFLDAVRRL-----QYLK 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  622 TEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKE-------GTEEKSTLLEKTEKELVQSKEQAAKTLNDK 694
Cdd:COG4942  143 YLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEeraaleaLKAERQKLLARLEKELAELAAELAELQQEA 222

                        250
                 ....*....|....*...
gi 24584806  695 EQLEKQISDLKQLAEQEK 712
Cdd:COG4942  223 EELEALIARLEAEAAAAA 240
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 581-827 3.03e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 3.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  581 KLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLR 660
Cdd:COG4942   21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  661 LQKEgteEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvREMTENAINQIQLEKESIEQQLALKQ 740
Cdd:COG4942  101 AQKE---ELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA----RREQAEELRADLAELAALRAELEAER 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  741 NELEDFQKKQSESEVHLQEIKAQNTQKdfelvesgesLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQL 820
Cdd:COG4942  174 AELEALLAELEEERAALEALKAERQKL----------LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                 ....*..
gi 24584806  821 QSKSAES 827
Cdd:COG4942  244 PAAGFAA 250
PRK09039 PRK09039
peptidoglycan -binding protein;
619-758 3.18e-06

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 51.12  E-value: 3.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   619 ILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDML-RLQKEgteekstlLEKTEKELVQSKEQAAKTLNDKEQL 697
Cdd:PRK09039   43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVaNLRAS--------LSAAEAERSRLQALLAELAGAGAAA 114

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806   698 EKQISDL-KQLAEQEKLvremTENAINQIQLEKESIEQ---QLALKQNELEDFQKKQSESEVHLQ 758
Cdd:PRK09039  115 EGRAGELaQELDSEKQV----SARALAQVELLNQQIAAlrrQLAALEAALDASEKRDRESQAKIA 175
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1275-1520 3.70e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 51.37  E-value: 3.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1275 LKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAtnkELQELLVK 1354
Cdd:COG3883   18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE---ELGERARA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1355 SQENEGNLQgeslavteKLQQLEQANGelkealcqkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQE 1434
Cdd:COG3883   95 LYRSGGSVS--------YLDVLLGSES------------FSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1435 ETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAND 1514
Cdd:COG3883  155 KLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAA 234


                 ....*.
gi 24584806 1515 AQKTAY 1520
Cdd:COG3883  235 AAAAAA 240
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
659-1090 3.86e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 3.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  659 LRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKEsiEQQLAL 738
Cdd:COG4717   83 AEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEER--LEELRE 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  739 KQNELEDFQKKQSESEVHLQEIKAQNT-QKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKE--Q 815
Cdd:COG4717  161 LEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEaaA 240

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  816 ELQQLQSK--SAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEA 893
Cdd:COG4717  241 LEERLKEArlLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEE 320

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  894 ANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVES-KTKQLEAANAALEK----VNKEYAESRAEASDLQDKV 968
Cdd:COG4717  321 LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEElQLEELEQEIAALLAeagvEDEEELRAALEQAEEYQEL 400

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  969 KEITDTLHAELQAERSSSSALHTKLSKfsDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGER 1048
Cdd:COG4717  401 KEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQEL 478

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 24584806 1049 KEKsfEESIKNLQEEVTKAKTenlelstgTQTTIKDLQERLE 1090
Cdd:COG4717  479 EEL--KAELRELAEEWAALKL--------ALELLEEAREEYR 510
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1277-1445 3.96e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.92  E-value: 3.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1277 ETQDQLLESQKKEKQLQE---EAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELL- 1352
Cdd:COG1579    4 EDLRALLDLQELDSELDRlehRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLg 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1353 -VKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKshnEIQDKLEQAQQKERT 1431
Cdd:COG1579   84 nVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA---ELDEELAELEAELEE 160

                        170
                 ....*....|....
gi 24584806 1432 LQEETSKLAEQLSQ 1445
Cdd:COG1579  161 LEAEREELAAKIPP 174
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1070-1551 3.98e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.76  E-value: 3.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1070 ENLELSTGTQ-TTIKDLQERLEITNAE--LQHKEKMASEDAQKIADLKTlVEAIQVANA--------NISATNAELSTVL 1138
Cdd:pfam12128  149 QNDRTLLGRErVELRSLARQFALCDSEspLRHIDKIAKAMHSKEGKFRD-VKSMIVAILeddgvvppKSRLNRQQVEHWI 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1139 EVLQAEKSETNHIFELFEMEADMNS-ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQaqqseqKLQQESQTSKE 1217
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEFNTlESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQ------LLRTLDDQWKE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1218 KLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIiEAQNTKLNESNV-QLENKTSCLKETQDQLLESQ---------K 1287
Cdd:pfam12128  302 KRDELNGELSAADAAVAKDRSELEALEDQHGAFLDA-DIETAAADQEQLpSWQSELENLEERLKALTGKHqdvtakynrR 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1288 KEKQLQEEAAKLSGeLQQVQEANGDIKDSLVKVEElvKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESL 1367
Cdd:pfam12128  381 RSKIKEQNNRDIAG-IKDKLAKIREARDRQLAVAE--DDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQAT 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1368 AVTEKLQQLEQANGEL---KEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL- 1443
Cdd:pfam12128  458 ATPELLLQLENFDERIeraREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLl 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1444 ----SQLKQANEELQKSLQQKQLLlekgnefdtqlaeyQKVIDEMDDAASVKSAL--------LEQLQ-NRVAELETALR 1510
Cdd:pfam12128  538 hflrKEAPDWEQSIGKVISPELLH--------------RTDLDPEVWDGSVGGELnlygvkldLKRIDvPEWAASEEELR 603

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 24584806   1511 QANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGA 1551
Cdd:pfam12128  604 ERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFA 644
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 694-831 4.07e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.92  E-value: 4.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  694 KEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQS------ESEVHLQEIKAQNTQK 767
Cdd:COG1579   26 LKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvrnnkEYEALQKEIESLKRRI 105

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806  768 DF---ELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAL 831
Cdd:COG1579  106 SDledEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 582-918 4.51e-06

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 51.75  E-value: 4.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    582 LAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRL 661
Cdd:pfam10174  361 LNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTT 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    662 QKEGTEEKSTLLEKTEKELVQSKEQAAKTLndkEQLEKQISDLKQ--------LAEQEKLVREMTENAINQIQ--LEKES 731
Cdd:pfam10174  441 LEEALSEKERIIERLKEQREREDRERLEEL---ESLKKENKDLKEkvsalqpeLTEKESSLIDLKEHASSLASsgLKKDS 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    732 ieqqlALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFEL-VESGESLKKLQQQLEQKTLGHEKLQAALEEL-------- 802
Cdd:pfam10174  518 -----KLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTnPEINDRIRLLEQEVARYKEESGKAQAEVERLlgilreve 592

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    803 --KKEKETIIKE---------KEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAE 871
Cdd:pfam10174  593 neKNDKDKKIAElesltlrqmKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELD 672

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 24584806    872 ETQSELKSTQSNLEAKSKQLEaangSLEEEAKKSghlLEQITKLKSE 918
Cdd:pfam10174  673 ATKARLSSTQQSLAEKDGHLT----NLRAERRKQ---LEEILEMKQE 712
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1205-1461 4.67e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.56  E-value: 4.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1205 EQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLeekvRESSSIIEAQNtklnESNVQLENktscLKETQDQLLE 1284
Cdd:COG3206  163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEF----RQKNGLVDLSE----EAKLLLQQ----LSELESQLAE 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1285 SQKKEKQLQEEAAKLSGELQQVQEANGDIKDSlvkveELVKVLEEKLQAATSQLDAQQATNKElqellvksqenegnlqg 1364
Cdd:COG3206  231 ARAELAEAEARLAALRAQLGSGPDALPELLQS-----PVIQQLRAQLAELEAELAELSARYTP----------------- 288

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1365 ESLAVTEKLQQLEQANGELKEalcqkenglkELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEqLS 1444
Cdd:COG3206  289 NHPDVIALRAQIAALRAQLQQ----------EAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR-LE 357

                        250
                 ....*....|....*..
gi 24584806 1445 QLKQANEELQKSLQQKQ 1461
Cdd:COG3206  358 REVEVARELYESLLQRL 374
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 760-1396 6.49e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 51.26  E-value: 6.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    760 IKAQNTQKD--FELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQ 837
Cdd:pfam05483  204 VQAENARLEmhFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDEN 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    838 LEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSleeeakKSGHLLeQITKLKS 917
Cdd:pfam05483  284 LKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKA------KAAHSF-VVTEFEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    918 EVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLhaelqAERSSSSALHTKLSKFS 997
Cdd:pfam05483  357 TTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKIL-----AEDEKLLDEKKQFEKIA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    998 DEIATGHKELTSKADAwsqemlqKEKELQELRQQLQDSQDSqtklkaegerkEKSFEESIKNLQEEVTKAKTENLELSTG 1077
Cdd:pfam05483  432 EELKGKEQELIFLLQA-------REKEIHDLEIQLTAIKTS-----------EEHYLKEVEDLKTELEKEKLKNIELTAH 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1078 tqttikdlqerleiTNAELQHKEKMASEDAQKIADLKTLVEAIqvananISATNAELSTVLEVLQAEKSETNhifelFEM 1157
Cdd:pfam05483  494 --------------CDKLLLENKELTQEASDMTLELKKHQEDI------INCKKQEERMLKQIENLEEKEMN-----LRD 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1158 EADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE 1237
Cdd:pfam05483  549 ELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAEN 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1238 ELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQqvQEANGDIKDSL 1317
Cdd:pfam05483  629 KQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEID--KRCQHKIAEMV 706

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806   1318 VKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKE 1396
Cdd:pfam05483  707 ALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
CagA_N pfam18971
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ...
 1241-1523 6.77e-06

CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.


Pssm-ID: 408741 [Multi-domain]  Cd Length: 876  Bit Score: 50.93  E-value: 6.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1241 QNLEEKvresssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQlqeeaAKLSGELQQVQEANGDIKDSLVKV 1320
Cdd:pfam18971  559 RNLENK-------LTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAE-----AKSTGNYDEVKKAQKDLEKSLRKR 626

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1321 EELVKVLEEKLQAAT---SQLDAQQATNKELQEL--LVKSQENEG--------NLQGESLAVTEKLQQLEQANGELKEAL 1387
Cdd:pfam18971  627 EHLEKEVEKKLESKSgnkNKMEAKAQANSQKDEIfaLINKEANRDaraiaytqNLKGIKRELSDKLEKISKDLKDFSKSF 706

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1388 CQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLqqKQLLLEkg 1467
Cdd:pfam18971  707 DEFKNGKNKDFSKAEETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSV--KDVIIN-- 782

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806   1468 nefdtqlaeyQKVIDEMDD---AASVKSAL--LEQLQNRVAELETALRQ--ANDAQKTAYLET 1523
Cdd:pfam18971  783 ----------QKVTDKVDNlnqAVSVAKAMgdFSRVEQVLADLKNFSKEqlAQQAQKNEDFNT 835
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 413-1436 7.05e-06

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 51.37  E-value: 7.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   413 VELESALDNERKKTEELQCSIDEAQFCGDELNAQSQ---VYKEKIHDLESKITKLVSATP-SLQSILppDLPSDDGA--- 485
Cdd:PTZ00440  487 EKKESSDSNYQEKVDELLQIINSIKEKNNIVNNNFKnieDYYITIEGLKNEIEGLIELIKyYLQSIE--TLIKDEKLkrs 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   486 LQEEIAK-----------------LQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSL 548
Cdd:PTZ00440  565 MKNDIKNkikyieenvdhikdiisLNDEIDNIIQQIEELINEALFNKEKFINEKNDLQEKVKYILNKFYKGDLQELLDEL 644

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   549 SECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVL-----RLSSELQNLKATSDSLESERVNKtdeceiLQTE 623
Cdd:PTZ00440  645 SHFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEKLEFMKSDNIdniikNLKKELQNLLSLKENIIKKQLNN------IEQD 718

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   624 VRMRDEQIRElnqQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQL---EKQ 700
Cdd:PTZ00440  719 ISNSLNQYTI---KYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDLPDGKNTYEEFLQYKDTIlnkENK 795

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   701 IS-DLKQLAEQEKLVREMTENAINQIQLEK-------ESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELV 772
Cdd:PTZ00440  796 ISnDINILKENKKNNQDLLNSYNILIQKLEahtekndEELKQLLQKFPTEDENLNLKELEKEFNENNQIVDNIIKDIENM 875

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   773 ESG-ESLKKLQQQLEqktlGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvqvqleqLQQQAAASGEE 851
Cdd:PTZ00440  876 NKNiNIIKTLNIAIN----RSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNE----------KLNLLNNLNKE 941

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   852 GSKTVAKLHDE-ISQLKSQAEETQSELKSTQSNLEAKSK-QLEaangSLEEEAKKSGHLLEQITKLKSEVGETQAALSSc 929
Cdd:PTZ00440  942 KEKIEKQLSDTkINNLKMQIEKTLEYYDKSKENINGNDGtHLE----KLDKEKDEWEHFKSEIDKLNVNYNILNKKIDD- 1016

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   930 hTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTS 1009
Cdd:PTZ00440 1017 -LIKKQHDDIIELIDKLIKEKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALLKKIDE 1095

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1010 KADAWSQEMLQKEKELQELRQQLQdsqdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTqttikdlqerl 1089
Cdd:PTZ00440 1096 NKNKLIEIKNKSHEHVVNADKEKN-------KQTEHYNKKKKSLEKIYKQMEKTLKELENMNLEDITLN----------- 1157

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1090 EITNAELQHKEKMASEDAQKIAD-----------LKTLVEAIQVANANISATNAELSTVLEVLQAEKSETnhifelfemE 1158
Cdd:PTZ00440 1158 EVNEIEIEYERILIDHIVEQINNeakksktimeeIESYKKDIDQVKKNMSKERNDHLTTFEYNAYYDKAT---------A 1228

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1159 ADMNSERLIEKVTGIKEElkethlqlDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQ------------QSL 1226
Cdd:PTZ00440 1229 SYENIEELTTEAKGLKGE--------ANRSTNVDELKEIKLQVFSYLQQVIKENNKMENALHEIKnmyeflisidseKIL 1300

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1227 QELQDSVKQKEELVQNLEEKVRESSSIIEaqntklnesnvQLENKTSCLKETQDQLLESQkKEKQLQEEAAKLSGELQQV 1306
Cdd:PTZ00440 1301 KEILNSTKKAEEFSNDAKKELEKTDNLIK-----------QVEAKIEQAKEHKNKIYGSL-EDKQIDDEIKKIEQIKEEI 1368

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1307 QEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEklQQLEQANGELKEA 1386
Cdd:PTZ00440 1369 SNKRKEINKYLSNIKSNKEKCDLHVRNASRGKDKIDFLNKHEAIEPSNSKEVNIIKITDNINKCK--QYSNEAMETENKA 1446

                        1050      1060      1070      1080      1090      1100
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806  1387 LCQKENGLK-------------------ELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEET 1436
Cdd:PTZ00440 1447 DENNDSIIKyekeitnilnnssilgkktKLEKKKKEATNIMDDINGEHSIIKTKLTKSSEKLNQLNEQP 1515
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
373-805 8.53e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 8.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   373 LREKQQHVEKlMVERDLDREDAQNQALQLQKNINELKAR-----IVELESALDNERKKTEELQCSIDEaqfcgdelnaqs 447
Cdd:PRK03918  343 LKKKLKELEK-RLEELEERHELYEEAKAKKEELERLKKRltgltPEKLEKELEELEKAKEEIEEEISK------------ 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   448 qvYKEKIHDLESKITKLVSATPSLQSIlPPDLPSDDGALQEEIAK-LQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLn 526
Cdd:PRK03918  410 --ITARIGELKKEIKELKKAIEELKKA-KGKCPVCGRELTEEHRKeLLEEYTAELKRIEKELKEIEEKERKLRKELREL- 485

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   527 EQIATLQSELVSKDEALEKfslsecgIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSEL---QNLKATS 603
Cdd:PRK03918  486 EKVLKKESELIKLKELAEQ-------LKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELeklEELKKKL 558

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   604 DSLESERVNKTDECEILQTEVRMRD-EQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEgteekstlLEKTEKELVQ 682
Cdd:PRK03918  559 AELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPFYNEYLELKDAEKELEREEKE--------LKKLEEELDK 630

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   683 SKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVRemtenainqIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKA 762
Cdd:PRK03918  631 AFEELAETEKRLEELRKELEELEKKYSEEEYEE---------LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 24584806   763 QNTqkdfELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKE 805
Cdd:PRK03918  702 ELE----EREKAKKELEKLEKALERVEELREKVKKYKALLKER 740
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
707-928 9.63e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.40  E-value: 9.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  707 LAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFqkKQSESEVHLQEIKAQNTQKdfelvesgesLKKLQQQLE 786
Cdd:COG3206  162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEF--RQKNGLVDLSEEAKLLLQQ----------LSELESQLA 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  787 QKTLGHEKLQAALEELKKEKETIIKE-----KEQELQQLQSKSAESESALKVVQVQLEqlqqqaaasgeEGSKTVAKLHD 861
Cdd:COG3206  230 EARAELAEAEARLAALRAQLGSGPDAlpellQSPVIQQLRAQLAELEAELAELSARYT-----------PNHPDVIALRA 298

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806  862 EISQLKSQ----AEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSS 928
Cdd:COG3206  299 QIAALRAQlqqeAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1182-1373 1.11e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 48.77  E-value: 1.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1182 LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSsiiEAQNTKL 1261
Cdd:COG1579   10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYE---EQLGNVR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1262 NESNVQlenktSCLKEtqdqlLESQKKEKQLQEEaaklsgELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQ 1341
Cdd:COG1579   87 NNKEYE-----ALQKE-----IESLKRRISDLED------EILELMERIEELEEELAELEAELAELEAELEEKKAELDEE 150

                        170       180       190
                 ....*....|....*....|....*....|...
gi 24584806 1342 QA-TNKELQELLVKSQENEGNLQGESLAVTEKL 1373
Cdd:COG1579  151 LAeLEAELEELEAEREELAAKIPPELLALYERI 183
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 696-832 1.18e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 48.38  E-value: 1.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  696 QLEKQISDL-KQLAEQEKLVREMtENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKaqnTQKDFELVES 774
Cdd:COG1579   21 RLEHRLKELpAELAELEDELAAL-EARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR---NNKEYEALQK 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806  775 G-ESLKKLQQQLEQKTLGH----EKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALK 832
Cdd:COG1579   97 EiESLKRRISDLEDEILELmeriEELEEELAELEAELAELEAELEEKKAELDEELAELEAELE 159
PRK12704 PRK12704
phosphodiesterase; Provisional
 1169-1353 1.35e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 49.78  E-value: 1.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1169 KVTGIKEELKEThlqLDERQKKFEEL-EEKLKQAQQSEQKLQQE-SQTSKEKLTEIQQslqeLQDSVKQKEELVQNLEEK 1246
Cdd:PRK12704   32 KIKEAEEEAKRI---LEEAKKEAEAIkKEALLEAKEEIHKLRNEfEKELRERRNELQK----LEKRLLQKEENLDRKLEL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1247 VRESSSIIEAQNTKLNESNVQLENKtsclKETQDQLLESQKKEkqlQEEAAKLSGElqqvqEANgdikdslvkvEELVKV 1326
Cdd:PRK12704  105 LEKREEELEKKEKELEQKQQELEKK----EEELEELIEEQLQE---LERISGLTAE-----EAK----------EILLEK 162

                         170       180       190
                  ....*....|....*....|....*....|...
gi 24584806  1327 LEEKLQAATSQL------DAQQATNKELQELLV 1353
Cdd:PRK12704  163 VEEEARHEAAVLikeieeEAKEEADKKAKEILA 195
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1103-1344 1.59e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1103 ASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQaeksetnhifelfemEADMNSERLIEKVTGIKEELKETHL 1182
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA---------------ALERRIAALARRIRALEQELAALEA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1183 QLDERQKKFEELEEKLKQAQQSEQK----LQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssiIEAQN 1258
Cdd:COG4942   84 ELAELEKEIAELRAELEAQKEELAEllraLYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEE----LRADL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1259 TKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQL 1338
Cdd:COG4942  160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239


                 ....*.
gi 24584806 1339 DAQQAT 1344
Cdd:COG4942  240 AERTPA 245
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
373-817 1.60e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 1.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  373 LREKQQHVEKLMVERDlDREDAQNQALQLQKNINELKARIVELESALDNER--KKTEELQCSIDEAQFCGDELNAQSQVY 450
Cdd:COG4717   80 LKEAEEKEEEYAELQE-ELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELEERLEEL 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  451 KEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQekmtiqqkEVESRIAEQLEEEQRLRENVKYLNEQIA 530
Cdd:COG4717  159 RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE--------ELQQRLAELEEELEEAQEELEELEEELE 230

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  531 TLQSELVSKDEALEKFSLSE--------CGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKAT 602
Cdd:COG4717  231 QLENELEAAALEERLKEARLllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAL 310

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  603 SDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEvttqlnVQKADSSALDDMLRLQKEGTE-EKSTLLEKTEKELV 681
Cdd:COG4717  311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEE------LQELLREAEELEEELQLEELEqEIAALLAEAGVEDE 384

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  682 QSKEQAAKTLNDKEQLEKQISDLK-QLAEQEKLVREMTENAI-NQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQE 759
Cdd:COG4717  385 EELRAALEQAEEYQELKEELEELEeQLEELLGELEELLEALDeEELEEELEELEEELEELEEELEELREELAELEAELEQ 464

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806  760 IKAQNtqkdfELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQEL 817
Cdd:COG4717  465 LEEDG-----ELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPV 517
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1194-1469 1.67e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 49.13  E-value: 1.67e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1194 LEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTS 1273
Cdd:COG4372   29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1274 CLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLV 1353
Cdd:COG4372  109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1354 KSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQ 1433
Cdd:COG4372  189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 24584806 1434 EETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNE 1469
Cdd:COG4372  269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNL 304
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 372-971 1.72e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.05  E-value: 1.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    372 LLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVE--LESALDNERKKTEELQCSIDEAQFCGDELNAQSQV 449
Cdd:TIGR00606  369 LIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAqlCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEI 448

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    450 YKEKIHDLESKITKLVSATPSLQSILppdlpsddgalqeeiaKLQEKMTiqQKEVESRIAEQLEEEQRLRENVKYLNEQI 529
Cdd:TIGR00606  449 LEKKQEELKFVIKELQQLEGSSDRIL----------------ELDQELR--KAERELSKAEKNSLTETLKKEVKSLQNEK 510

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    530 ATLQSELVSKDEALEKfslsecgiENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESE 609
Cdd:TIGR00606  511 ADLDRKLRKLDQEMEQ--------LNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSK 582

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    610 RVnktdecEILQTEVRMRDEQ--IRELNQQLDEVTTQLNVQKADSSALDDMLrLQKEGTEEKSTLLEKTEKELVQSKEQA 687
Cdd:TIGR00606  583 SK------EINQTRDRLAKLNkeLASLEQNKNHINNELESKEEQLSSYEDKL-FDVCGSQDEESDLERLKEEIEKSSKQR 655

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    688 AKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQK 767
Cdd:TIGR00606  656 AMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGR 735

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    768 DFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQE---------LQQLQSKSAESESalKVVQVQL 838
Cdd:TIGR00606  736 QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAkvcltdvtiMERFQMELKDVER--KIAQQAA 813

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    839 EQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQ---SNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKL 915
Cdd:TIGR00606  814 KLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQeqiQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVEL 893

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    916 KSEVGETQAALSSCHT----DVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEI 971
Cdd:TIGR00606  894 STEVQSLIREIKDAKEqdspLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNI 953
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 379-1262 2.00e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.84  E-value: 2.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    379 HVEKL---MVERDLDREDAQNQalqlqknineLKARIVELESALDNERKKTEELQCSIDEAQfcgdeLNAQSQVYKEKIH 455
Cdd:pfam12128  180 HIDKIakaMHSKEGKFRDVKSM----------IVAILEDDGVVPPKSRLNRQQVEHWIRDIQ-----AIAGIMKIRPEFT 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    456 DLESKITKLVSATPSLQSilppdlpsddgaLQEEIAKLQEKMTIQQKEVESRIAEQleeEQRLRENVKYLNEQIATLQSE 535
Cdd:pfam12128  245 KLQQEFNTLESAELRLSH------------LHFGYKSDETLIASRQEERQETSAEL---NQLLRTLDDQWKEKRDELNGE 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    536 LVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERV--NK 613
Cdd:pfam12128  310 LSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKeqNN 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    614 TDECEILQTEVRMRDEQIRelnqqldevttQLNVQKADSSALDDMLRLQKEG-----TEEKSTLLEKTEKELVQsKEQAA 688
Cdd:pfam12128  390 RDIAGIKDKLAKIREARDR-----------QLAVAEDDLQALESELREQLEAgklefNEEEYRLKSRLGELKLR-LNQAT 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    689 KTLNDKEQLEKQISDLKQLAE-QEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQK 767
Cdd:pfam12128  458 ATPELLLQLENFDERIERAREeQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLL 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    768 DFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQsksaesesalkvvqvqleqlqqqaaa 847
Cdd:pfam12128  538 HFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRID-------------------------- 591

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    848 sgeegsktVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKsghLLEQITKLKSEvGETQAALS 927
Cdd:pfam12128  592 --------VPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASRE---ETFARTALKNA-RLDLRRLF 659

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    928 SCHTDVESK-TKQLEAANA-ALEKVNKEYAESRAEASDLQDKVKEITDTL----HAELQAERSSSSALHTKLSKFSDEIA 1001
Cdd:pfam12128  660 DEKQSEKDKkNKALAERKDsANERLNSLEAQLKQLDKKHQAWLEEQKEQKrearTEKQAYWQVVEGALDAQLALLKAAIA 739

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1002 ---TGHKELTSKADAWSQEMLQK-----------EKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKA 1067
Cdd:pfam12128  740 arrSGAKAELKALETWYKRDLASlgvdpdviaklKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNI 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1068 KTENLELstgtQTTIKDLQERLEITNAELQhKEKMASEDAQ---------------KIADLKTLVEAIQvANANISATNA 1132
Cdd:pfam12128  820 ERAISEL----QQQLARLIADTKLRRAKLE-MERKASEKQQvrlsenlrglrcemsKLATLKEDANSEQ-AQGSIGERLA 893

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1133 ELSTVLEVLQAEKSETNHIFELFEM--------EADMNSERLIEKVTGIKEELkethLQLDERQKKFEELEEKLK-QAQQ 1203
Cdd:pfam12128  894 QLEDLKLKRDYLSESVKKYVEHFKNviadhsgsGLAETWESLREEDHYQNDKG----IRLLDYRKLVPYLEQWFDvRVPQ 969

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806   1204 SEQKLQQESQTSKEKLTEIQQSLQELQDSVK-QKEELVQNLE-----EKVRESSSIIEAQNTKLN 1262
Cdd:pfam12128  970 SIMVLREQVSILGVDLTEFYDVLADFDRRIAsFSRELQREVGeeaffEGVSESAVRIRSKVSELE 1034
46 PHA02562
endonuclease subunit; Provisional
 1081-1319 2.23e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.24  E-value: 2.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1081 TIKDLQERLE-ITNAELQHKEKMASEDAQKIADLKTLVEAIQVAnanisatnaelstVLEVLQAEKSETNHIFELFEMEA 1159
Cdd:PHA02562  199 TYNKNIEEQRkKNGENIARKQNKYDELVEEAKTIKAEIEELTDE-------------LLNLVMDIEDPSAALNKLNTAAA 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1160 DMNSErlIEKVTGIKEELKETHL------QLDERQKKFEELEEKLKQAQQSEQKL---QQESQTSKEKLTEIQQSLQELQ 1230
Cdd:PHA02562  266 KIKSK--IEQFQKVIKMYEKGGVcptctqQISEGPDRITKIKDKLKELQHSLEKLdtaIDELEEIMDEFNEQSKKLLELK 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1231 DSVKQKEELVQNLEEKVRESSSIIEaqntKLNESNVqleNKTSCLKETQDQLlesqkkeKQLQEEAAKLSGELQQVQEAN 1310
Cdd:PHA02562  344 NKISTNKQSLITLVDKAKKVKAAIE----ELQAEFV---DNAEELAKLQDEL-------DKIVKTKSELVKEKYHRGIVT 409


                  ....*....
gi 24584806  1311 GDIKDSLVK 1319
Cdd:PHA02562  410 DLLKDSGIK 418
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
908-1512 2.29e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  908 LLEQITKLKSEVGEtqaaLSSCHTDVESKTKQLEAAnAALEKVNKEYAESRAEASDLQD--------KVKEITDTLHAEL 979
Cdd:COG4913  223 TFEAADALVEHFDD----LERAHEALEDAREQIELL-EPIRELAERYAAARERLAELEYlraalrlwFAQRRLELLEAEL 297

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  980 QAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLqdsqdsqTKLKAEGERKEKSFEESIKN 1059
Cdd:COG4913  298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERL-------ERELEERERRRARLEALLAA 370

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1060 LQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVL- 1138
Cdd:COG4913  371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALa 450

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1139 EVLQAEKSETNHIFELFEMEADMNS-----ERLI--------------EKVTGIKEELK-ETHLQLderqkkfeeleEKL 1198
Cdd:COG4913  451 EALGLDEAELPFVGELIEVRPEEERwrgaiERVLggfaltllvppehyAAALRWVNRLHlRGRLVY-----------ERV 519

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1199 KQAQQSEQKLQQESQTSKEKLT--------EIQQSLQELQDSVKqkeelVQNLEEKVRESSSI-IEAQ------------ 1257
Cdd:COG4913  520 RTGLPDPERPRLDPDSLAGKLDfkphpfraWLEAELGRRFDYVC-----VDSPEELRRHPRAItRAGQvkgngtrhekdd 594

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1258 NTKLNESNV-------QLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG---ELQQVQEANGDIKDslvkveelVKVL 1327
Cdd:COG4913  595 RRRIRSRYVlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQErreALQRLAEYSWDEID--------VASA 666

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1328 EEKLQAATSQLDAQQATNKELQELlvksQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE---- 1403
Cdd:COG4913  667 EREIAELEAELERLDASSDDLAAL----EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedl 742

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1404 --SNTVLESQKKSHNEIQDKLEqaQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLekGNEFDTQLAEYQKVI 1481
Cdd:COG4913  743 arLELRALLEERFAAALGDAVE--RELRENLEERIDALRARLNRAEEELERAMRAFNREWPAE--TADLDADLESLPEYL 818

                        650       660       670       680
                 ....*....|....*....|....*....|....*....|
gi 24584806 1482 DEMDDAASV---------KSALLEQLQNRVAELETALRQA 1512
Cdd:COG4913  819 ALLDRLEEDglpeyeerfKELLNENSIEFVADLLSKLRRA 858
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1190-1537 2.32e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.27  E-value: 2.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1190 KFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKeelvQNLEEKVRESSSIIEAQNTKLNESNVQLE 1269
Cdd:TIGR00606  183 RYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSK----EAQLESSREIVKSYENELDPLKNRLKEIE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1270 NKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQV-QEANGDIKDSLVKVEELVKVLEEKLQAATSQLdaqQATNKEL 1348
Cdd:TIGR00606  259 HNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVfQGTDEQLNDLYHNHQRTVREKERELVDCQREL---EKLNKER 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1349 QELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKE----------------LQGKLDESNTVlesqK 1412
Cdd:TIGR00606  336 RLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFErgpfserqiknfhtlvIERQEDEAKTA----A 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1413 KSHNEIQDKLEQAQQK-----------ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVi 1481
Cdd:TIGR00606  412 QLCADLQSKERLKQEQadeirdekkglGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKA- 490

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806   1482 dEMDDAASVKSALLEQLQNRVAELETALRQanDAQKTAYLE-TKELRRQLESLELEK 1537
Cdd:TIGR00606  491 -EKNSLTETLKKEVKSLQNEKADLDRKLRK--LDQEMEQLNhHTTTRTQMEMLTKDK 544
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 687-904 2.45e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  687 AAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQ 766
Cdd:COG4942   15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  767 KDFELVESGESLKKL---QQQLEQKT-----------LGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALK 832
Cdd:COG4942   95 LRAELEAQKEELAELlraLYRLGRQPplalllspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24584806  833 VVqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 904
Cdd:COG4942  175 EL---------------EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 369-1027 2.53e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.27  E-value: 2.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    369 MQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVE---LESALDNERKKTEELQCSidEAQFCGDELNA 445
Cdd:TIGR00606  417 LQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKElqqLEGSSDRILELDQELRKA--ERELSKAEKNS 494

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    446 QSQVYKEKIHDLESKitklvsatpslqsilPPDLPSDDGALQEEIAKLQEKMTiQQKEVESRIAEQLEEEQRLRENVKYL 525
Cdd:TIGR00606  495 LTETLKKEVKSLQNE---------------KADLDRKLRKLDQEMEQLNHHTT-TRTQMEMLTKDKMDKDEQIRKIKSRH 558

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    526 NEQIATLQSELVSKDEaLEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSEL------QNL 599
Cdd:TIGR00606  559 SDELTSLLGYFPNKKQ-LEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDE 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    600 KATSDSLESERVNKTDECEILQTEVRMRDEQIREL---NQQLDEVTTQLNVQKAD----SSALDDMLRLQKEGTEEKSTL 672
Cdd:TIGR00606  638 ESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLtdeNQSCCPVCQRVFQTEAElqefISDLQSKLRLAPDKLKSTESE 717

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    673 LEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQlaEQEKLVREMTE--NAINQIQLEKESIEQQLALKQNELED----- 745
Cdd:TIGR00606  718 LKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRN--KLQKVNRDIQRlkNDIEEQETLLGTIMPEEESAKVCLTDvtime 795

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    746 -FQKKQSESEVHLQEIKAQNTQKDFELvesgeSLKKLQQQLEQKTLGHEKLQAALEELKKeketIIKEKEQELQQLQSKS 824
Cdd:TIGR00606  796 rFQMELKDVERKIAQQAAKLQGSDLDR-----TVQQVNQEKQEKQHELDTVVSKIELNRK----LIQDQQEQIQHLKSKT 866

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    825 AESESAlKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 904
Cdd:TIGR00606  867 NELKSE-KLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVND 945

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    905 SGHLLEQITKLKSEV------------GETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQD------ 966
Cdd:TIGR00606  946 IKEKVKNIHGYMKDIenkiqdgkddylKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDnltlrk 1025

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806    967 ---KVKEITDTLHAEL----QAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQE 1027
Cdd:TIGR00606 1026 renELKEVEEELKQHLkemgQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELRE 1093
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
393-592 3.13e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 3.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  393 DAQNQALQLQKNINELKARIVELES---ALDNERKKTEELQCSIDE-AQFCGDELNAQSqvYKEKIHDLESKITKLVSAT 468
Cdd:COG4913  607 DNRAKLAALEAELAELEEELAEAEErleALEAELDALQERREALQRlAEYSWDEIDVAS--AEREIAELEAELERLDASS 684

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  469 PSLQsilppdlpsddgALQEEIAKLQEkmtiQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSL 548
Cdd:COG4913  685 DDLA------------ALEEQLEELEA----ELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR 748

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 24584806  549 SECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRL 592
Cdd:COG4913  749 ALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
PRK11281 PRK11281
mechanosensitive channel MscK;
976-1513 3.31e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 48.75  E-value: 3.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   976 HAELQAERSSSSALHTKLSKFSD-EIATGHKELTSKADAWSQEMLQK----EKELQELRqqlqdsqdsqtKLKAEGERKE 1050
Cdd:PRK11281   28 RAASNGDLPTEADVQAQLDALNKqKLLEAEDKLVQQDLEQTLALLDKidrqKEETEQLK-----------QQLAQAPAKL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1051 KSFEESIKNLQEEVTKAKTENLElstgtQTTIKDLQERLEITNAELQhkekmaseDAQkiadlktlvEAIQVANANISAt 1130
Cdd:PRK11281   97 RQAQAELEALKDDNDEETRETLS-----TLSLRQLESRLAQTLDQLQ--------NAQ---------NDLAEYNSQLVS- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1131 naeLSTVLEVLQAEKSEtnhifelfemeadmNSERLiekvtgikeelkethlqlderqkkfEELEEKLKQAQQSEQKLQQ 1210
Cdd:PRK11281  154 ---LQTQPERAQAALYA--------------NSQRL-------------------------QQIRNLLKGGKVGGKALRP 191

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1211 ESQTskekLTEIQQSLQELQDSVKQKE----ELVQNLEEKVREsssiieaqntKLNESNVQLEnktsclKETQD-QLLES 1285
Cdd:PRK11281  192 SQRV----LLQAEQALLNAQNDLQRKSlegnTQLQDLLQKQRD----------YLTARIQRLE------HQLQLlQEAIN 251

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1286 QKKEKQLQEEAAklsgELQQVQEANGDIKDSLVKveelvkvleeklqaatsqldAQQATNKELQELLVKSqenegnlqge 1365
Cdd:PRK11281  252 SKRLTLSEKTVQ----EAQSQDEAARIQANPLVA--------------------QELEINLQLSQRLLKA---------- 297

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1366 slavTEKLQQLEQANGELK---EALCQKENGLKE----LQGKLdesntVLesqkkshNEIqdkLEQAQQKERTLQeETSK 1438
Cdd:PRK11281  298 ----TEKLNTLTQQNLRVKnwlDRLTQSERNIKEqisvLKGSL-----LL-------SRI---LYQQQQALPSAD-LIEG 357

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806  1439 LAEQLSQLKQAneelQKSLQQKQLLLEKGNEFDTQLAEYQKVidEMDDAasVKSALLEQLQNRVAELETALRQAN 1513
Cdd:PRK11281  358 LADRIADLRLE----QFEINQQRDALFQPDAYIDKLEAGHKS--EVTDE--VRDALLQLLDERRELLDQLNKQLN 424
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1066-1422 3.75e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 48.74  E-value: 3.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1066 KAKTENLELSTGTQTTIKDLQERLEiTNAELQHKEKMASEDAQKIADlkTLVEAIQVANANISATNAELSTVLEVLQAEK 1145
Cdd:PLN02939   36 RARRRGFSSQQKKKRGKNIAPKQRS-SNSKLQSNTDENGQLENTSLR--TVMELPQKSTSSDDDHNRASMQRDEAIAAID 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1146 SETNHIFELFEMEADMNSERLIEKvtgIKEELKETHLQLDERQKKFEELEEKLKQaqqsEQKLQQESQTSKEKLTEIQQS 1225
Cdd:PLN02939  113 NEQQTNSKDGEQLSDFQLEDLVGM---IQNAEKNILLLNQARLQALEDLEKILTE----KEALQGKINILEMRLSETDAR 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1226 LQeLQDSVKQKEELVQNLEEKVRESSSIIEAQN-----------TKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQE 1294
Cdd:PLN02939  186 IK-LAAQEKIHVEILEEQLEKLRNELLIRGATEglcvhslskelDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEK 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1295 EAAKLSGELQQVQ----EANGDI-KDSLVKVE---ELVKVLEEKLQAATSQLDAQQAT---NKELQELLVKSQEN--EGN 1361
Cdd:PLN02939  265 ERSLLDASLRELEskfiVAQEDVsKLSPLQYDcwwEKVENLQDLLDRATNQVEKAALVldqNQDLRDKVDKLEASlkEAN 344

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806  1362 LQGESLAVTEKLQQ--------LEQANGELKEALCQKENGLKELQGKLdeSNTVLESQKKSHNEIQDKL 1422
Cdd:PLN02939  345 VSKFSSYKVELLQQklklleerLQASDHEIHSYIQLYQESIKEFQDTL--SKLKEESKKRSLEHPADDM 411
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1164-1303 5.07e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.46  E-value: 5.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1164 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQ---ESQTSKEkLTEIQQSLQELQDSVKQKEELV 1240
Cdd:COG1579   34 AELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlgNVRNNKE-YEALQKEIESLKRRISDLEDEI 112

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806 1241 QNLEEKVRESSSIIEAQNTKLNESNVQLENKTsclKETQDQLLESQKKEKQLQEEAAKLSGEL 1303
Cdd:COG1579  113 LELMERIEELEEELAELEAELAELEAELEEKK---AELDEELAELEAELEELEAEREELAAKI 172
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 794-961 5.12e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.46  E-value: 5.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  794 KLQAALEELKKEKETI---IKEKEQELQQLQSKSAESESALKVVQvqleqlqqqaaasgeegsKTVAKLHDEISQLKSQA 870
Cdd:COG1579   14 ELDSELDRLEHRLKELpaeLAELEDELAALEARLEAAKTELEDLE------------------KEIKRLELEIEEVEARI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  871 EETQSELKSTQSN--LEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALE 948
Cdd:COG1579   76 KKYEEQLGNVRNNkeYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELE 155

                        170
                 ....*....|...
gi 24584806  949 KVNKEYAESRAEA 961
Cdd:COG1579  156 AELEELEAEREEL 168
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1095-1542 5.38e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 47.89  E-value: 5.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1095 ELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEK--SETNHIFELFEMEADMN-SERLIEKVT 1171
Cdd:pfam10174  213 EELHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGllHTEDREEEIKQMEVYKShSKFMKNKID 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1172 GIKEEL--KETHL------------QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE 1237
Cdd:pfam10174  293 QLKQELskKESELlalqtkletltnQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1238 ELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDI---- 1313
Cdd:pfam10174  373 EEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKerii 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1314 --------KDSLVKVEELvKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1385
Cdd:pfam10174  453 erlkeqreREDRERLEEL-ESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKE 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1386 ALCQKENGLKELQGkldesntvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQlllE 1465
Cdd:pfam10174  532 ECSKLENQLKKAHN--------AEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKD---K 600

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806   1466 KGNEFDTQLAEYQKviDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAyletkeLRRQLESL--ELEKSREVL 1542
Cdd:pfam10174  601 KIAELESLTLRQMK--EQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNS------QQLQLEELmgALEKTRQEL 671
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 373-545 6.89e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 6.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  373 LREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQfcgDELNAQSQVYKE 452
Cdd:COG4942   32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---AELEAQKEELAE 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  453 KIHDLEskitkLVSATPSLQSILPPDLPSDDG---------------------ALQEEIAKLQEKMTIQQKEVESRIAEQ 511
Cdd:COG4942  109 LLRALY-----RLGRQPPLALLLSPEDFLDAVrrlqylkylaparreqaeelrADLAELAALRAELEAERAELEALLAEL 183

                        170       180       190
                 ....*....|....*....|....*....|....
gi 24584806  512 LEEEQRLRENVKYLNEQIATLQSELVSKDEALEK 545
Cdd:COG4942  184 EEERAALEALKAERQKLLARLEKELAELAAELAE 217
PRK11281 PRK11281
mechanosensitive channel MscK;
669-916 7.91e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 7.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   669 KSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQ-LAEQEKLVREMTEN---------AINQIQLEKESI---EQQ 735
Cdd:PRK11281   50 KQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQqLAQAPAKLRQAQAElealkddndEETRETLSTLSLrqlESR 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   736 LALKQNELEDFQKK-----------QSESE----------VHLQEIKAQ-NTQKDFELVESGESLKKLQQQL-------- 785
Cdd:PRK11281  130 LAQTLDQLQNAQNDlaeynsqlvslQTQPEraqaalyansQRLQQIRNLlKGGKVGGKALRPSQRVLLQAEQallnaqnd 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   786 -EQKTL-GHEKLQAALEELKKEKETIIKEKEQELQQLQskSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAK---LH 860
Cdd:PRK11281  210 lQRKSLeGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQ--EAINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQeleIN 287

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806   861 DEISQLKSQAEETQSELksTQSNLEAKSkQLEAANGSleEEAKKsghllEQITKLK 916
Cdd:PRK11281  288 LQLSQRLLKATEKLNTL--TQQNLRVKN-WLDRLTQS--ERNIK-----EQISVLK 333
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1621-1638 9.54e-05

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.91  E-value: 9.54e-05
                           10
                   ....*....|....*...
gi 24584806   1621 RLFCDICDEFDqHDTEDC 1638
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1368-1573 9.57e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 9.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1368 AVTEKLQQLEQANGELKEALCQKengLKELQGKLDEsntvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLK 1447
Cdd:COG4717   50 RLEKEADELFKPQGRKPELNLKE---LKELEEELKE----AEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1448 QANE------ELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYL 1521
Cdd:COG4717  123 KLLQllplyqELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 24584806 1522 ETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKI 1573
Cdd:COG4717  203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLI 254
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1078-1485 9.62e-05

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 47.14  E-value: 9.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1078 TQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQvanANISATNAELSTVLEVLQAEKSETNHIFELFE- 1156
Cdd:PRK04778  110 IESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELR---KSLLANRFSFGPALDELEKQLENLEEEFSQFVe 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1157 -------MEADMNSERLIEKVTGIKEELKETHLQLDERQKKF----EELEEKLKQAQQS-----EQKLQQESQTSKEKLT 1220
Cdd:PRK04778  187 ltesgdyVEAREILDQLEEELAALEQIMEEIPELLKELQTELpdqlQELKAGYRELVEEgyhldHLDIEKEIQDLKEQID 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1221 EIQQSLQELQdsVKQKEELVQNLEEKVRESSSIIEaqnTKLNESNVQLENKtsclKETQDQLLESQKKEKQLQEEAAKLS 1300
Cdd:PRK04778  267 ENLALLEELD--LDEAEEKNEEIQERIDQLYDILE---REVKARKYVEKNS----DTLPDFLEHAKEQNKELKEEIDRVK 337

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1301 -------GELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATS---QLDAQQATNKELQELLVKSQENEGNLQGESLAVT 1370
Cdd:PRK04778  338 qsytlneSELESVRQLEKQLESLEKQYDEITERIAEQEIAYSElqeELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAR 417

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1371 EKLQQLEQANGELKEALcQKEN--GL--------KELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK-- 1438
Cdd:PRK04778  418 EKLERYRNKLHEIKRYL-EKSNlpGLpedylemfFEVSDEIEALAEELEEKPINMEAVNRLLEEATEDVETLEEETEElv 496

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 24584806  1439 ----LAEQLSQ----LKQANEELQKSLQQKQLLLeKGNEFDTQLAEYQKVIDEMD 1485
Cdd:PRK04778  497 enatLTEQLIQyanrYRSDNEEVAEALNEAERLF-REYDYKAALEIIATALEKVE 550
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1226-1450 1.05e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1226 LQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQ 1305
Cdd:COG3883   18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1306 vQEANGDIKDSLVKVEEL------VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQA 1379
Cdd:COG3883   98 -SGGSVSYLDVLLGSESFsdfldrLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806 1380 NGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1450
Cdd:COG3883  177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 730-1312 1.18e-04

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 47.05  E-value: 1.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    730 ESIEQQLALKQNELEDFQKKQSEsevhLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETI 809
Cdd:pfam07111   59 QALSQQAELISRQLQELRRLEEE----VRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNL 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    810 IKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTV----AKLHDEISQLKSQAEETQSELKSTQSNLE 885
Cdd:pfam07111  135 EEGSQRELEEIQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLetkrAGEAKQLAEAQKEAELLRKQLSKTQEELE 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    886 AKSKQLEAANGSLEEEAKKSGH----------LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEK------ 949
Cdd:pfam07111  215 AQVTLVESLRKYVGEQVPPEVHsqtwelerqeLLDTMQHLQEDRADLQATVELLQVRVQSLTHMLALQEEELTRkiqpsd 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    950 -VNKEYAES-RAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSkfsdeiatghkELTSKADAWSQEMLQKEKELQE 1027
Cdd:pfam07111  295 sLEPEFPKKcRSLLNRWREKVFALMVQLKAQDLEHRDSVKQLRGQVA-----------ELQEQVTSQSQEQAILQRALQD 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1028 LRQQLQDSQDSQTKLKAEGERKEKSfeesiKNLQEEVTKAKTENLELSTG----TQTTIKDLQERLEITNAELQHKEKMA 1103
Cdd:pfam07111  364 KAAEVEVERMSAKGLQMELSRAQEA-----RRRQQQQTASAEEQLKFVVNamssTQIWLETTMTRVEQAVARIPSLSNRL 438

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1104 SEDAQKIADLKTLVeAIQVANANISA-----------TNAELSTVLEVLQAEKSETNHIFELfemeadmnSERLIEKVTG 1172
Cdd:pfam07111  439 SYAVRKVHTIKGLM-ARKVALAQLRQescpppppappVDADLSLELEQLREERNRLDAELQL--------SAHLIQQEVG 509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1173 IKEELKEThlqlderqkkfeELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDS-----------VKQKEELVQ 1241
Cdd:pfam07111  510 RAREQGEA------------ERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESteeaaslrqelTQQQEIYGQ 577

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1242 NLEEKVRESSSIIEAQ--NTKLNESNVQLENKTSCLKETQDQLLESQKKE-----KQLQEEAAKLSGE--LQQVQEANGD 1312
Cdd:pfam07111  578 ALQEKVAEVETRLREQlsDTKRRLNEARREQAKAVVSLRQIQHRATQEKErnqelRRLQDEARKEEGQrlARRVQELERD 657
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1214-1531 1.24e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1214 TSKEKLTEIQQSLQELQdsvkqkeeLVQnLEEKVRESSSiieAQNTKLNESNVQLENKTSCLKetqdQLLESQKKEKQLQ 1293
Cdd:PRK05771   13 TLKSYKDEVLEALHELG--------VVH-IEDLKEELSN---ERLRKLRSLLTKLSEALDKLR----SYLPKLNPLREEK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1294 EEAAKLSGElqqvqEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQ-----ELLVKSQENEGNLQGESLA 1368
Cdd:PRK05771   77 KKVSVKSLE-----ELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEpwgnfDLDLSLLLGFKYVSVFVGT 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1369 VTEKLQQLEQANGELKEALCQKENGLKE------LQGKLDESNTVLESQKKSHNEIQDkleqaqqkERTLQEETSKLAEQ 1442
Cdd:PRK05771  152 VPEDKLEELKLESDVENVEYISTDKGYVyvvvvvLKELSDEVEEELKKLGFERLELEE--------EGTPSELIREIKEE 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1443 LSQLKQANEELQKSLqqkqlllekgNEFDTQLAEYQKVIDEMDDAASVKSALLEQL--------------QNRVAELETA 1508
Cdd:PRK05771  224 LEEIEKERESLLEEL----------KELAKKYLEELLALYEYLEIELERAEALSKFlktdktfaiegwvpEDRVKKLKEL 293

                         330       340
                  ....*....|....*....|...
gi 24584806  1509 LRQANDaqKTAYLETKELRRQLE 1531
Cdd:PRK05771  294 IDKATG--GSAYVEFVEPDEEEE 314
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
505-749 1.35e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  505 ESRIAEQLEEEQRLRENVKYLNEQIATLQSELvskdEALEKFSLSECGIENLRRELELLKeenekQAQEAQAEFTRKLAE 584
Cdd:COG4913  609 RAKLAALEAELAELEEELAEAEERLEALEAEL----DALQERREALQRLAEYSWDEIDVA-----SAEREIAELEAELER 679

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  585 ksveVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNvqkadssalddmlRLQKE 664
Cdd:COG4913  680 ----LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE-------------AAEDL 742

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  665 GTEEKSTLLEKTEKELVQSKEQAAKtlndKEQLEKQISDLKQLAEQ--EKLVREMTE------NAINQIQLEKESIEQQL 736
Cdd:COG4913  743 ARLELRALLEERFAAALGDAVEREL----RENLEERIDALRARLNRaeEELERAMRAfnrewpAETADLDADLESLPEYL 818

                        250
                 ....*....|....*..
gi 24584806  737 A----LKQNELEDFQKK 749
Cdd:COG4913  819 AlldrLEEDGLPEYEER 835
mukB PRK04863
chromosome partition protein MukB;
853-1519 1.45e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.87  E-value: 1.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   853 SKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAkskqLEAANGSLEEEAKK-SGHLLEQITKLKSevgetQAALSSCHT 931
Cdd:PRK04863  285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAE----LNEAESDLEQDYQAaSDHLNLVQTALRQ-----QEKIERYQA 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   932 DVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTL-----------------HAELQAERSSSSALHtkLS 994
Cdd:PRK04863  356 DLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLadyqqaldvqqtraiqyQQAVQALERAKQLCG--LP 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   995 KFSDEIATG-HKELTSKADAWSQEMLQKEKEL---QELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEvtKAK 1068
Cdd:PRK04863  434 DLTADNAEDwLEEFQAKEQEATEELLSLEQKLsvaQAAHSQFEQAYQLVRKIAGEVSRSEawDVARELLRRLREQ--RHL 511

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1069 TENLElstGTQTTIKDLQERLEitnaelQHKekmaseDAQKIADlktlvEAIQVANANIsaTNAELstvLEVLQAEKSET 1148
Cdd:PRK04863  512 AEQLQ---QLRMRLSELEQRLR------QQQ------RAERLLA-----EFCKRLGKNL--DDEDE---LEQLQEELEAR 566

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1149 nhifelfemeadmnserliekvtgiKEELKETHLQLDERQkkfEELEEKLKQAQQSEQKLQQES---QTSKEKLTEIQQS 1225
Cdd:PRK04863  567 -------------------------LESLSESVSEARERR---MALRQQLEQLQARIQRLAARApawLAAQDALARLREQ 618

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1226 LQELQDSVKQKEELVQNLEEKVREsssiieaqntkLNESNVQLENKTSCLKETQDQLLESQKKE-KQLQEEAAKLSGELQ 1304
Cdd:PRK04863  619 SGEEFEDSQDVTEYMQQLLERERE-----------LTVERDELAARKQALDEEIERLSQPGGSEdPRLNALAERFGGVLL 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1305 -------QVQEA---------------------------------------NGDI---KDSLVKVEEL-----VKVLEEK 1330
Cdd:PRK04863  688 seiyddvSLEDApyfsalygparhaivvpdlsdaaeqlagledcpedlyliEGDPdsfDDSVFSVEELekavvVKIADRQ 767

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1331 LQ-------------AATSQLDAQQATNKELQELLVKSQENEGNLQ----------GESLAV------------------ 1369
Cdd:PRK04863  768 WRysrfpevplfgraAREKRIEQLRAEREELAERYATLSFDVQKLQrlhqafsrfiGSHLAVafeadpeaelrqlnrrrv 847

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1370 --TEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVL-ESQKKSHNEIQDKLEQAQQKERTLQEETSKLA------ 1440
Cdd:PRK04863  848 elERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLLAdETLADRVEEIREQLDEAEEAKRFVQQHGNALAqlepiv 927

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1441 -------EQLSQLKQA---NEELQKSLQQKQLLLEKGNEFDTQLAeYQKVIDEMDDAasvkSALLEQLQNRVAELETALR 1510
Cdd:PRK04863  928 svlqsdpEQFEQLKQDyqqAQQTQRDAKQQAFALTEVVQRRAHFS-YEDAAEMLAKN----SDLNEKLRQRLEQAEQERT 1002


                  ....*....
gi 24584806  1511 QANDAQKTA 1519
Cdd:PRK04863 1003 RAREQLRQA 1011
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 858-1552 1.68e-04

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 46.72  E-value: 1.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   858 KLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAkksgHLLEQITKLKSEVGETQAALSSCHTDVESKT 937
Cdd:PRK10246  202 KLQAQASGVALLTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSL----NWLTRLDELQQEASRRQQALQQALAAEEKAQ 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   938 KQLEAAN-------------------AALEKVNKEYAESRA---EASDLQDKVKEITDTLHAELQAERSSSS---ALHTK 992
Cdd:PRK10246  278 PQLAALSlaqparqlrphweriqeqsAALAHTRQQIEEVNTrlqSTMALRARIRHHAAKQSAELQAQQQSLNtwlAEHDR 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   993 LSKFSDEIATGHKELT------SKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTK 1066
Cdd:PRK10246  358 FRQWNNELAGWRAQFSqqtsdrEQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVP 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1067 AKTENLELstgtQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAiqvananiSATNAELSTVLEVLQAEK- 1145
Cdd:PRK10246  438 QQKRLAQL----QVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQ--------EARIKDLEAQRAQLQAGQp 505

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1146 ----SETNH--IFELFEMEADMNSERL--IEK-VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSK 1216
Cdd:PRK10246  506 cplcGSTSHpaVEAYQALEPGVNQSRLdaLEKeVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVC 585

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1217 EKLTEIQQSLQELQDSVKQKEELVQNLEE--KVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQL---LESQKKEKQ 1291
Cdd:PRK10246  586 ASLNITLQPQDDIQPWLDAQEEHERQLRLlsQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYaltLPQEDEEAS 665

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1292 LQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQgeslavte 1371
Cdd:PRK10246  666 WLATRQQEAQSWQQRQNELTALQNRIQQLTPLLETLPQSDDLPHSEETVALDNWRQVHEQCLSLHSQLQTLQ-------- 737

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1372 klQQLEQANGELKEALCQKENGLKelqgkldesNTVLESqkkshneiqdkleQAQQKERTLQEETsklAEQLSQLKQAne 1451
Cdd:PRK10246  738 --QQDVLEAQRLQKAQAQFDTALQ---------ASVFDD-------------QQAFLAALLDEET---LTQLEQLKQN-- 788

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1452 eLQKSLQQKQLLLEKGNEfdtQLAEYQKVIDE-MDDAASVksallEQLQNRVAELETALRQANDAQktayletKELRRQL 1530
Cdd:PRK10246  789 -LENQRQQAQTLVTQTAQ---ALAQHQQHRPDgLDLTVTV-----EQIQQELAQLAQQLRENTTRQ-------GEIRQQL 852

                         730       740
                  ....*....|....*....|..
gi 24584806  1531 ESlELEKSREVLSLKAQMNGAS 1552
Cdd:PRK10246  853 KQ-DADNRQQQQALMQQIAQAT 873
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 695-972 1.71e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 46.58  E-value: 1.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   695 EQLEKQisdLKQLAEQEKLVREMTENAINQIQLEKESIEQQLalKQNELEDF----QKKQSESEVHLQEIKAQNTQKDFE 770
Cdd:PTZ00108 1002 GKLERE---LARLSNKVRFIKHVINGELVITNAKKKDLVKEL--KKLGYVRFkdiiKKKSEKITAEEEEGAEEDDEADDE 1076

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   771 LVESG--------------------ESLKKLQQQLEQKTLGHEKLQAA------LEELKKEKETIIKEKEQE----LQQL 820
Cdd:PTZ00108 1077 DDEEElgaavsydyllsmpiwsltkEKVEKLNAELEKKEKELEKLKNTtpkdmwLEDLDKFEEALEEQEEVEekeiAKEQ 1156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   821 QSKSAESESALKVVQ-VQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLE 899
Cdd:PTZ00108 1157 RLKSKTKGKASKLRKpKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPK 1236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806   900 EEAKKSGHLLEQITKLKSEVGETQaalSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEIT 972
Cdd:PTZ00108 1237 KSSVKRLKSKKNNSSKSSEDNDEF---SSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPT 1306
PRK01156 PRK01156
chromosome segregation protein; Provisional
 580-1258 1.79e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.43  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   580 RKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDeceiLQTEVRMRDEQIRELNQQLDEvttqlnvqkaDSSALDDML 659
Cdd:PRK01156  152 KKILDEILEINSLERNYDKLKDVIDMLRAEISNIDY----LEEKLKSSNLELENIKKQIAD----------DEKSHSITL 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   660 RLQKEGTEEkstlLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQlAEQEKLVREMTENAINQIQLEKESIEQQLAL- 738
Cdd:PRK01156  218 KEIERLSIE----YNNAMDDYNNLKSALNELSSLEDMKNRYESEIKT-AESDLSMELEKNNYYKELEERHMKIINDPVYk 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   739 KQNELEDFQKKQSESEVHLQEIKaqntQKDFELVESGESLKKLQQQleqktlghEKLQAALEELKKEKETIikekEQELQ 818
Cdd:PRK01156  293 NRNYINDYFKYKNDIENKKQILS----NIDAEINKYHAIIKKLSVL--------QKDYNDYIKKKSRYDDL----NNQIL 356

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   819 QLQSKSAESESALKVVQVQLEQLqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSL 898
Cdd:PRK01156  357 ELEGYEMDYNSYLKSIESLKKKI--------EEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSL 428

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   899 EEEAKKSGHLLEQITKlKSEVGETQAALSSCHTDV-ESKTKQL-EAANAALEKVNKEYAESRAEASDLQDKVKEitdtlh 976
Cdd:PRK01156  429 NQRIRALRENLDELSR-NMEMLNGQSVCPVCGTTLgEEKSNHIiNHYNEKKSRLEEKIREIEIEVKDIDEKIVD------ 501

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   977 aelqaerssssalhtkLSKFSDEIATGHKEltskadawsqEMLQKEKELQELRQQLQDSQDSQTKLKaEGERKEKSFEES 1056
Cdd:PRK01156  502 ----------------LKKRKEYLESEEIN----------KSINEYNKIESARADLEDIKIKINELK-DKHDKYEEIKNR 554

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1057 IKNLQEEVTKAKTE--NLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEaiqvananisatnael 1134
Cdd:PRK01156  555 YKSLKLEDLDSKRTswLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYID---------------- 618

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1135 STVLEVLQAEKSETNHIFELFEMEadmnseRLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQT 1214
Cdd:PRK01156  619 KSIREIENEANNLNNKYNEIQENK------ILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDD 692

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....
gi 24584806  1215 SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQN 1258
Cdd:PRK01156  693 AKANRARLESTIEILRTRINELSDRINDINETLESMKKIKKAIG 736
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 747-988 1.79e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 1.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  747 QKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQktlgHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAE 826
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA----LERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  827 SESALKVVQVQLEQLQQQAAASGEegsktvaklHDEISQLKSQAEETQSE--LKSTQSNLEAKSKQLEAANGSLEEEAKK 904
Cdd:COG4942   95 LRAELEAQKEELAELLRALYRLGR---------QPPLALLLSPEDFLDAVrrLQYLKYLAPARREQAEELRADLAELAAL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  905 SGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERS 984
Cdd:COG4942  166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245


                 ....
gi 24584806  985 SSSA 988
Cdd:COG4942  246 AGFA 249
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
682-885 1.81e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.16  E-value: 1.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  682 QSKEQAAKTLndkEQLEKQISDLK-QLAEQEKLVRE-MTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQE 759
Cdd:COG3206  168 LRREEARKAL---EFLEEQLPELRkELEEAEAALEEfRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAA 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  760 IKAQNTQKDFELVESGES---------LKKLQQQLEQKTL----GHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAE 826
Cdd:COG3206  245 LRAQLGSGPDALPELLQSpviqqlraqLAELEAELAELSArytpNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEA 324

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806  827 SESALKVVQVQLEQLQQQaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLE 885
Cdd:COG3206  325 LQAREASLQAQLAQLEAR--------LAELPELEAELRRLEREVEVARELYESLLQRLE 375
PRK01156 PRK01156
chromosome segregation protein; Provisional
 781-1385 1.83e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.43  E-value: 1.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   781 LQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvqvqleqlqqqaaasgEEGSKTVAKLH 860
Cdd:PRK01156  188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNL-------------------KSALNELSSLE 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   861 DEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQL 940
Cdd:PRK01156  249 DMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAII 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   941 EAAnAALEKVNKEYAESRAEASDLQDKVKEItDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQ 1020
Cdd:PRK01156  329 KKL-SVLQKDYNDYIKKKSRYDDLNNQILEL-EGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDA 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1021 KEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTT---IKDLQERLEITNAELQ 1097
Cdd:PRK01156  407 IKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSnhiINHYNEKKSRLEEKIR 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1098 HKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVlqaeksetnhifelfEMEADMNSErliekvtgikEEL 1177
Cdd:PRK01156  487 EIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARA---------------DLEDIKIKI----------NEL 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1178 KETHLQLDERQKKFEELE-EKLKQaqQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEA 1256
Cdd:PRK01156  542 KDKHDKYEEIKNRYKSLKlEDLDS--KRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1257 QNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSlvkvEELVKVLEEKLQAATS 1336
Cdd:PRK01156  620 SIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDI----EDNLKKSRKALDDAKA 695

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 24584806  1337 QLDAQQATNKEL----QELLVKSQENEGNLqgeslavtEKLQQLEQANGELKE 1385
Cdd:PRK01156  696 NRARLESTIEILrtriNELSDRINDINETL--------ESMKKIKKAIGDLKR 740
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 359-752 2.07e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 2.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    359 ILATPKSQFsMQDLLREKQQHVEKLMVE-------RDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQC 431
Cdd:pfam07888   23 LLVVPRAEL-LQNRLEECLQERAELLQAqeaanrqREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEE 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    432 SIDEAQFCGDELNAQSQVYKEKIHDLESKITKlvsatpslqsilppdlpsddgaLQEEIAKLQEKMTIQQKEVEsRIAEQ 511
Cdd:pfam07888  102 KYKELSASSEELSEEKDALLAQRAAHEARIRE----------------------LEEDIKTLTQRVLERETELE-RMKER 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    512 LEEEQRLRENVKYLNEQiatLQSELVSKDEALEKFSLSECGIENlrreLELLKEENEKQAQEAQAEFTRKLAEKSVEVLR 591
Cdd:pfam07888  159 AKKAGAQRKEEEAERKQ---LQAKLQQTEEELRSLSKEFQELRN----SLAQRDTQVLQLQDTITTLTQKLTTAHRKEAE 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    592 LSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVtTQLNVQKADSSAldDMLRLQKEGTEEKST 671
Cdd:pfam07888  232 NEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQA-AQLTLQLADASL--ALREGRARWAQERET 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    672 LLEKTEKELVQSKEQAAKTLNDKEQLEKQISDlKQLAEQEkLVREMTENAINQIQLEKESIEQQLALK--QNELEDFQKK 749
Cdd:pfam07888  309 LQQSAEADKDRIEKLSAELQRLEERLQEERME-REKLEVE-LGREKDCNRVQLSESRRELQELKASLRvaQKEKEQLQAE 386


                   ...
gi 24584806    750 QSE 752
Cdd:pfam07888  387 KQE 389
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 921-1538 2.12e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 46.58  E-value: 2.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    921 ETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITD------TLHAELQAERSSSSALHTKLS 994
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDeiiyinKLKLELKEKIKNISDKNEYIK 620

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    995 KfsdeiATGHKELTSKADAWSQEmLQKEKELQELRQQLQDSQDSQTkLKAEgerKEKSFEESIKNLQEEVTKAKTENLEL 1074
Cdd:TIGR01612  621 K-----AIDLKKIIENNNAYIDE-LAKISPYQVPEHLKNKDKIYST-IKSE---LSKIYEDDIDALYNELSSIVKENAID 690

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1075 STGTQTTIKDLQERLEITNAELQHKEKMASE------DAQKIADLKTLVEAIQVANANIsatNAELSTVLEVLQA-EKSE 1147
Cdd:TIGR01612  691 NTEDKAKLDDLKSKIDKEYDKIQNMETATVElhlsniENKKNELLDIIVEIKKHIHGEI---NKDLNKILEDFKNkEKEL 767

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1148 TNHIFELFEMEADMNSERliEKVTGIK--------------EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQE-- 1211
Cdd:TIGR01612  768 SNKINDYAKEKDELNKYK--SKISEIKnhyndqinidnikdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDfl 845

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1212 ---------SQTSKEKLTEIQQSLQELQDSVKQK--EELVQNLEEKVRESSSIIEAQNTKLNE--SNVQLENKTS----C 1274
Cdd:TIGR01612  846 nkvdkfinfENNCKEKIDSEHEQFAELTNKIKAEisDDKLNDYEKKFNDSKSLINEINKSIEEeyQNINTLKKVDeyikI 925

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1275 LKETQDQLLESQKKEKQLQEeaaKLSGELQQVQEAN-------GDIKDSLV-KVEELVKVLEEklqaatSQLDAQQATNK 1346
Cdd:TIGR01612  926 CENTKESIEKFHNKQNILKE---ILNKNIDTIKESNlieksykDKFDNTLIdKINELDKAFKD------ASLNDYEAKNN 996

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1347 ELQELLVKSQENEGNLQGESL---------AVTEKLQQLEQANGELKE-------ALCQKENGLKELQGKLDES--NTVL 1408
Cdd:TIGR01612  997 ELIKYFNDLKANLGKNKENMLyhqfdekekATNDIEQKIEDANKNIPNieiaihtSIYNIIDEIEKEIGKNIELlnKEIL 1076

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1409 ESQKKS---HNEIQDKLEQAQQKErTLQEETSKLAEQLSQLKQ----ANEELQKSLQQKQLLLEKG----NEFDTQLAEY 1477
Cdd:TIGR01612 1077 EEAEINitnFNEIKEKLKHYNFDD-FGKEENIKYADEINKIKDdiknLDQKIDHHIKALEEIKKKSenyiDEIKAQINDL 1155

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806   1478 QKVIDEMDDAASVKSaLLEQLQNRVAELetalrqanDAQKTAYLETKELRRQLESLELEKS 1538
Cdd:TIGR01612 1156 EDVADKAISNDDPEE-IEKKIENIVTKI--------DKKKNIYDEIKKLLNEIAEIEKDKT 1207
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 757-988 2.19e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 2.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  757 LQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEketiIKEKEQELQQLQSKSAESESALKVVQV 836
Cdd:COG3883   18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAE----IDKLQAEIAEAEAEIEERREELGERAR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  837 QLEQLQQQAAASGE-EGSKTVAKLHDEISQLKSQAEETQS---ELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQI 912
Cdd:COG3883   94 ALYRSGGSVSYLDVlLGSESFSDFLDRLSALSKIADADADlleELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806  913 TKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSA 988
Cdd:COG3883  174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGA 249
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 1199-1455 2.24e-04

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 45.19  E-value: 2.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1199 KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEA---QNTKLNESNVQLENKTSCL 1275
Cdd:pfam15905   55 KVKSLELKKKSQKNLKESKDQKELEKEIRALVQERGEQDKRLQALEEELEKVEAKLNAavrEKTSLSASVASLEKQLLEL 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1276 KETQDqLLESQKKEKQLQEEAAKLSGELQQVQ-EANGDIKDSLVKVEELvkvlEEKLQAATSQLDAQQATNKELQELLVK 1354
Cdd:pfam15905  135 TRVNE-LLKAKFSEDGTQKKMSSLSMELMKLRnKLEAKMKEVMAKQEGM----EGKLQVTQKNLEHSKGKVAQLEEKLVS 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1355 S--QENEGNLQGESL--------AVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHN-------- 1416
Cdd:pfam15905  210 TekEKIEEKSETEKLleyitelsCVSEQVEKYKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNekcklles 289

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 24584806   1417 EIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQK 1455
Cdd:pfam15905  290 EKEELLREYEEKEQTLNAELEELKEKLTLEEQEHQKLQQ 328
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1158-1385 2.79e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 44.90  E-value: 2.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1158 EADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE 1237
Cdd:COG1340   19 ELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNELREELDELR 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1238 ELVQNLEEKVRESSSI---IEAQNTKLNESNVQLENKTSCLKETQD--QLLESQKKEKQLQEEAAKLSGELQQVQEANGD 1312
Cdd:COG1340   99 KELAELNKAGGSIDKLrkeIERLEWRQQTEVLSPEEEKELVEKIKEleKELEKAKKALEKNEKLKELRAELKELRKEAEE 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806 1313 IKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1385
Cdd:COG1340  179 IHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRK 251
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1216-1476 2.83e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 45.45  E-value: 2.83e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1216 KEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSsIIEAQNTKLNESNvqlenktscLKETQDQLLESqkkEKQLQEE 1295
Cdd:COG0497  154 EELLEEYREAYRAWRALKKELEELRADEAERARELD-LLRFQLEELEAAA---------LQPGEEEELEE---ERRRLSN 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1296 AAKLSGELQQVQEAngdIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVT---EK 1372
Cdd:COG0497  221 AEKLREALQEALEA---LSGGEGGALDLLGQALRALERLAEYDPSLAELAERLESALIELEEAASELRRYLDSLEfdpER 297

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1373 LQQLEQANGELKeALCQKENG--------LKELQGKLDEsntvLESqkkshneIQDKLEQAQQKERTLQEETSKLAEQLS 1444
Cdd:COG0497  298 LEEVEERLALLR-RLARKYGVtveellayAEELRAELAE----LEN-------SDERLEELEAELAEAEAELLEAAEKLS 365

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 24584806 1445 QL-KQANEELQKSLQQ--KQLLLEKGnEFDTQLAE 1476
Cdd:COG0497  366 AArKKAAKKLEKAVTAelADLGMPNA-RFEVEVTP 399
COG5022 COG5022
Myosin heavy chain [General function prediction only];
579-899 3.05e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.84  E-value: 3.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  579 TRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEIL---QTEVRMRDEQIRELNQQLDEVTTQLNVQKAD---- 651
Cdd:COG5022  829 EKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYlqsAQRVELAERQLQELKIDVKSISSLKLVNLELesei 908

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  652 ---SSALDDMLRLQKEGTEEKSTLLEKTEKElVQSKEQAAKTLNDKEQLEK---QISDLKQLAEQEKLVREMTENAINQI 725
Cdd:COG5022  909 ielKKSLSSDLIENLEFKTELIARLKKLLNN-IDLEEGPSIEYVKLPELNKlheVESKLKETSEEYEDLLKKSTILVREG 987

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  726 QLEKESIE---QQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALE 800
Cdd:COG5022  988 NKANSELKnfkKELAELSKQYGALQESTKQLKELPVEVaeLQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYK 1067

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  801 ELKKEKETIIKEKEQELQQLQSKSAESESALKvvqvqleqlqqQAAASGEEGSKTVAKLHDEISQLKSQAEETQSE--LK 878
Cdd:COG5022 1068 ALKLRRENSLLDDKQLYQLESTENLLKTINVK-----------DLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISkfLS 1136

                        330       340
                 ....*....|....*....|.
gi 24584806  879 STQSNLEAKSKQLEAANGSLE 899
Cdd:COG5022 1137 QLVNTLEPVFQKLSVLQLELD 1157
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 369-1068 3.14e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 3.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    369 MQDLLREKQQHVEKLMVERDldredAQNQALQLQKNINELKARIVEL---ESALDNERKKTEeLQCSIDEAQFCGDELNA 445
Cdd:TIGR00618  231 LREALQQTQQSHAYLTQKRE-----AQEEQLKKQQLLKQLRARIEELraqEAVLEETQERIN-RARKAAPLAAHIKAVTQ 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    446 QSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYL 525
Cdd:TIGR00618  305 IEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    526 NEQIATLQSELVSKDEALEKFSlsecgiENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQnlkatsds 605
Cdd:TIGR00618  385 QQQKTTLTQKLQSLCKELDILQ------REQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCT-------- 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    606 leservnktdeceilQTEVRMRDEQIRELNQQLDEvttqlnvqkadssalddmlRLQKEGTEEKSTLLEKTEKELVQSKE 685
Cdd:TIGR00618  451 ---------------AQCEKLEKIHLQESAQSLKE-------------------REQQLQTKEQIHLQETRKKAVVLARL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    686 QaaktlndkEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKesIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNT 765
Cdd:TIGR00618  497 L--------ELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQR--GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQ 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    766 QKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQA 845
Cdd:TIGR00618  567 EIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLT 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    846 AASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAA 925
Cdd:TIGR00618  647 ALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENA 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    926 LSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHK 1005
Cdd:TIGR00618  727 SSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584806   1006 ELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAK 1068
Cdd:TIGR00618  807 EIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQA 869
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1240-1547 3.24e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 3.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1240 VQNLEEKVRESSSIIEAQNTKLNESNVQLENKTScLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEA---------- 1309
Cdd:COG3096  274 MRHANERRELSERALELRRELFGARRQLAEEQYR-LVEMARELEELSARESDLEQDYQAASDHLNLVQTAlrqqekiery 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1310 NGDIKDSLVKVEELVKVLE---EKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQAngelkEA 1386
Cdd:COG3096  353 QEDLEELTERLEEQEEVVEeaaEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKA-----RA 427

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1387 LCQK--------ENGLKELQGKLDE-SNTVLESQKK------SHNEIQDKLE------------QAQQKERTLQE---ET 1436
Cdd:COG3096  428 LCGLpdltpenaEDYLAAFRAKEQQaTEEVLELEQKlsvadaARRQFEKAYElvckiageversQAWQTARELLRryrSQ 507

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1437 SKLAEQLSQLKQANEELQKSLQQKQlllekgnEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQ 1516
Cdd:COG3096  508 QALAQRLQQLRAQLAELEQRLRQQQ-------NAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR 580

                        330       340       350
                 ....*....|....*....|....*....|.
gi 24584806 1517 KTAYLETKELRRQLESLElekSREVLSLKAQ 1547
Cdd:COG3096  581 SELRQQLEQLRARIKELA---ARAPAWLAAQ 608
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1382-1571 3.53e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.82  E-value: 3.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1382 ELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEEtskLAEQLSQLKQANEELQKSLQQKQ 1461
Cdd:COG3883   20 AKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAE---IAEAEAEIEERREELGERARALY 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1462 -------------------------LLLEKGNEFDTQ-LAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDA 1515
Cdd:COG3883   97 rsggsvsyldvllgsesfsdfldrlSALSKIADADADlLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806 1516 QKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLA 1571
Cdd:COG3883  177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1046-1437 3.61e-04

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 45.33  E-value: 3.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1046 GERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANA 1125
Cdd:COG5185  177 KKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLE 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1126 NISATNAELSTVLEVLQAEKSE-----TNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQldeRQKKFEELEEKLKQ 1200
Cdd:COG5185  257 KLVEQNTDLRLEKLGENAESSKrlnenANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLA---AAEAEQELEESKRE 333

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1201 AQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNlEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKET-Q 1279
Cdd:COG5185  334 TETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKS-SEELDSFKDTIESTKESLDEIPQNQRGYAQEILATlE 412

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1280 DQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLeeklqaatSQLDAQQATNKELQELLVKSQENE 1359
Cdd:COG5185  413 DTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEE--------SQSRLEEAYDEINRSVRSKKEDLN 484

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1360 GNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTV--LESQKKSHNEIQDKLEQAQQKERTLQEETS 1437
Cdd:COG5185  485 EELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRArgYAHILALENLIPASELIQASNAKTDGQAAN 564
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
613-812 3.81e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 3.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  613 KTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKA---DSSALDDMLRLQKEgteekstlLEKTEKELvqskEQAAK 689
Cdd:COG4913  615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeYSWDEIDVASAERE--------IAELEAEL----ERLDA 682

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  690 TLNDKEQLEKQISDLKQLAEQeklvremTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDF 769
Cdd:COG4913  683 SSDDLAALEEQLEELEAELEE-------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF 755

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 24584806  770 ELVESGESLKKLQQQLEQKTlghEKLQAALEELKKEKETIIKE 812
Cdd:COG4913  756 AAALGDAVERELRENLEERI---DALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1429-1598 4.33e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1429 ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL---EKGNEFDTQLAEYQkVIDEMDDAASV--KSALLEQLQNRVA 1503
Cdd:COG4913  220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpirELAERYAAARERLA-ELEYLRAALRLwfAQRRLELLEAELE 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1504 ELETALRQANDAQKtayletkELRRQLESLEleksREVLSLKAQMNGASsrsgkGDEVESLDietslAKINFLNSIIADM 1583
Cdd:COG4913  299 ELRAELARLEAELE-------RLEARLDALR----EELDELEAQIRGNG-----GDRLEQLE-----REIERLERELEER 357

                        170
                 ....*....|....*
gi 24584806 1584 QQKNDALKAKVQTLE 1598
Cdd:COG4913  358 ERRRARLEALLAALG 372
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
579-828 4.48e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  579 TRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQT---------EVRMRDEQIRELNQQLDEVTtqlnvqk 649
Cdd:COG4913  609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELEAELERLD------- 681

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  650 ADSSALDdmlRLQKEgteekstlLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI---- 725
Cdd:COG4913  682 ASSDDLA---ALEEQ--------LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLElral 750

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  726 ------QLEKESIEQQLALK-QNELEDFQKKQSESEVHLQEIKAQ-NTQKDFELVESGESLKKLQQQLEQktlgHEKLQA 797
Cdd:COG4913  751 leerfaAALGDAVERELRENlEERIDALRARLNRAEEELERAMRAfNREWPAETADLDADLESLPEYLAL----LDRLEE 826

                        250       260       270
                 ....*....|....*....|....*....|...
gi 24584806  798 -ALEELKKE-KETIIKEKEQELQQLQSKSAESE 828
Cdd:COG4913  827 dGLPEYEERfKELLNENSIEFVADLLSKLRRAI 859
PRK11637 PRK11637
AmiB activator; Provisional
 1215-1451 4.88e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 44.68  E-value: 4.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1215 SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKlnesnvqlenktscLKETQDQLLESQKKEKQLQE 1294
Cdd:PRK11637   45 NRDQLKSIQQDIAAKEKSVRQQQQQRASLLAQLKKQEEAISQASRK--------------LRETQNTLNQLNKQIDELNA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1295 EAAKLsgELQQVQeangdikdslvkveelvkvlEEKLQAAtsQLDA--QQATNKELQELLvksqENEGNLQGESL----- 1367
Cdd:PRK11637  111 SIAKL--EQQQAA--------------------QERLLAA--QLDAafRQGEHTGLQLIL----SGEESQRGERIlayfg 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1368 ----AVTEKLQQLEQANGELKEalcQKenglKELQGKLDESNTVLESQKKShneiQDKLEQAQQ-KERTLQEETSKLAE- 1441
Cdd:PRK11637  163 ylnqARQETIAELKQTREELAA---QK----AELEEKQSQQKTLLYEQQAQ----QQKLEQARNeRKKTLTGLESSLQKd 231

                         250
                  ....*....|..
gi 24584806  1442 --QLSQLKQaNE 1451
Cdd:PRK11637  232 qqQLSELRA-NE 242
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1044-1238 5.17e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 5.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1044 AEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAELQHKEKmasEDAQKIADLKTLVEAIQVA 1123
Cdd:COG3883   26 SELQAELEAAQAELDALQAELEELNEEYNEL----QAELEALQAEIDKLQAEIAEAEA---EIEERREELGERARALYRS 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1124 NANISATNAelstvleVLQAEK-SETNHIFELFEMEADMNSErLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQ 1202
Cdd:COG3883   99 GGSVSYLDV-------LLGSESfSDFLDRLSALSKIADADAD-LLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 24584806 1203 QSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEE 1238
Cdd:COG3883  171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELA 206
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 914-1285 5.34e-04

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 44.46  E-value: 5.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    914 KLKSEVGETQAALsschTDVESKTKQLeaaNAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKL 993
Cdd:pfam06160   83 KAKKALDEIEELL----DDIEEDIKQI---LEELDELLESEEKNREEVEELKDKYRELRKTLLANRFSYGPAIDELEKQL 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    994 SKFSDEIATgHKELTSKAD-AWSQEMLQK-EKELQELRQQLQDSQDSQTKLK----------AEGERK---------EKS 1052
Cdd:pfam06160  156 AEIEEEFSQ-FEELTESGDyLEAREVLEKlEEETDALEELMEDIPPLYEELKtelpdqleelKEGYREmeeegyaleHLN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1053 FEESIKNLQEEV--TKAKTENLELsTGTQTTIKDLQERLEiTNAELQHKEKMASEDAQKiaDLKTLVEAIQVANANISAT 1130
Cdd:pfam06160  235 VDKEIQQLEEQLeeNLALLENLEL-DEAEEALEEIEERID-QLYDLLEKEVDAKKYVEK--NLPEIEDYLEHAEEQNKEL 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1131 NAELSTVLE--VLQAEKSETNHIFE--LFEMEADMNS--ERLIEKV---TGIKEELKETHLQLDERQKKFEELEEKLKQA 1201
Cdd:pfam06160  311 KEELERVQQsyTLNENELERVRGLEkqLEELEKRYDEivERLEEKEvaySELQEELEEILEQLEEIEEEQEEFKESLQSL 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1202 QQSEQKLQQESQTSKEKLTEIQQSL---------QELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENkt 1272
Cdd:pfam06160  391 RKDELEAREKLDEFKLELREIKRLVeksnlpglpESYLDYFFDVSDEIEDLADELNEVPLNMDEVNRLLDEAQDDVDT-- 468

                          410
                   ....*....|...
gi 24584806   1273 scLKETQDQLLES 1285
Cdd:pfam06160  469 --LYEKTEELIDN 479
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1164-1485 5.45e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 5.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1164 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNL 1243
Cdd:COG4372   48 EQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1244 EEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1323
Cdd:COG4372  128 EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEK 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1324 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE 1403
Cdd:COG4372  208 LIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEA 287

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1404 SNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1483
Cdd:COG4372  288 LEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGV 367


                 ..
gi 24584806 1484 MD 1485
Cdd:COG4372  368 AD 369
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 392-1211 5.70e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.78  E-value: 5.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    392 EDAQNQALQLQKNINELKARIVELESALDNERKK-----------TEELQCSIDEAQFCGDELNAQsqvykekiHDLESK 460
Cdd:pfam01576  253 EEETAQKNNALKKIRELEAQISELQEDLESERAArnkaekqrrdlGEELEALKTELEDTLDTTAAQ--------QELRSK 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    461 ITKLVSatpSLQSILPPDLPSDDGALQEeiaklqekMTIQQKEVESRIAEQLEEEQRLRENvkyLNEQIATLQSElvSKD 540
Cdd:pfam01576  325 REQEVT---ELKKALEEETRSHEAQLQE--------MRQKHTQALEELTEQLEQAKRNKAN---LEKAKQALESE--NAE 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    541 EALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEftRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEIL 620
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESE--RQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    621 QTEVRMRDEQIRELNQQLDEVTTQLnvqkadssalddmlrlqKEGTEEKSTLLEKTEKElVQSKEQAAKTLndkEQLEKQ 700
Cdd:pfam01576  467 ESQLQDTQELLQEETRQKLNLSTRL-----------------RQLEDERNSLQEQLEEE-EEAKRNVERQL---STLQAQ 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    701 ISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAqNTQKDFELVesgESLKK 780
Cdd:pfam01576  526 LSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLV-DLDHQRQLV---SNLEK 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    781 LQQQLEQkTLGHEKLQAA--------LEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGE-- 850
Cdd:pfam01576  602 KQKKFDQ-MLAEEKAISAryaeerdrAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKnv 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    851 -EGSKTVAKLHDEISQLKSQAEETQSELKSTQS-------NLEAK----------------------SKQLEAANGSLEE 900
Cdd:pfam01576  681 hELERSKRALEQQVEEMKTQLEELEDELQATEDaklrlevNMQALkaqferdlqardeqgeekrrqlVKQVRELEAELED 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    901 EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHA--- 977
Cdd:pfam01576  761 ERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNlea 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    978 ---ELQAERSSSSALHTKLSKFSDEIAtghKELTSKADawSQEMLQKEKELQELRqqlqdsqdsQTKLKAEGERKEKSFE 1054
Cdd:pfam01576  841 ellQLQEDLAASERARRQAQQERDELA---DEIASGAS--GKSALQDEKRRLEAR---------IAQLEEELEEEQSNTE 906

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1055 ESIKNLQEEVTKAKTENLELSTGTQTTIK--DLQERLEITNAELqhKEKMASEDAQKIADLKTLVEAIQvananisATNA 1132
Cdd:pfam01576  907 LLNDRLRKSTLQVEQLTTELAAERSTSQKseSARQQLERQNKEL--KAKLQEMEGTVKSKFKSSIAALE-------AKIA 977

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1133 ELSTVLEVLQAEKSETNHIF-----ELFEMEADMNSERliEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQK 1207
Cdd:pfam01576  978 QLEEQLEQESRERQAANKLVrrtekKLKEVLLQVEDER--RHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRK 1055


                   ....
gi 24584806   1208 LQQE 1211
Cdd:pfam01576 1056 LQRE 1059
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1163-1385 5.82e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.82  E-value: 5.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1163 SERLIEKVtgiKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQElqdsvkQKEELVQN 1242
Cdd:PRK00409  500 PENIIEEA---KKLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQE------EEDKLLEE 570

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1243 LEEKVREsssIIEAqntklnesnvqlenktscLKETQDQLLesqkKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1322
Cdd:PRK00409  571 AEKEAQQ---AIKE------------------AKKEADEII----KELRQLQKGGYASVKAHELIEARKRLNKANEKKEK 625

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806  1323 LVKVLEEKlqaatsqldaqqatNKELQ--------------ELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1385
Cdd:PRK00409  626 KKKKQKEK--------------QEELKvgdevkylslgqkgEVLSIPDDKEAIVQAGIMKMKVPLSDLEKIQKPKKK 688
46 PHA02562
endonuclease subunit; Provisional
 1216-1463 5.87e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 5.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1216 KEKLTEIQQSLQEL---QDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQL-ENKTSCLKETQDQLLEsqkkekq 1291
Cdd:PHA02562  173 KDKIRELNQQIQTLdmkIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEaKTIKAEIEELTDELLN------- 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1292 LQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEE--KLQAATSQLDaqqatnkELQELLVKSQENEGNLQGESLAV 1369
Cdd:PHA02562  246 LVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKggVCPTCTQQIS-------EGPDRITKIKDKLKELQHSLEKL 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1370 TEKLQQLEQANGELKEAlcQKEngLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQA 1449
Cdd:PHA02562  319 DTAIDELEEIMDEFNEQ--SKK--LLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKT 394

                         250
                  ....*....|....
gi 24584806  1450 NEELQKSLQQKQLL 1463
Cdd:PHA02562  395 KSELVKEKYHRGIV 408
PRK01156 PRK01156
chromosome segregation protein; Provisional
 966-1466 6.31e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.51  E-value: 6.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   966 DKVKEITDtlhaELQAERSSSSALHTKLSKFSDEIATGHKELTSkaDAWSQEMLQKEKElqELRQQLQDSQDSQTKLKAE 1045
Cdd:PRK01156  169 DKLKDVID----MLRAEISNIDYLEEKLKSSNLELENIKKQIAD--DEKSHSITLKEIE--RLSIEYNNAMDDYNNLKSA 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1046 GERKeKSFEESIKNLQEEVTKAKTEnLELSTGTQTTIKDLQERL-EITNAELQHKEKMASEDAQKIADLKTLVEAIQVAN 1124
Cdd:PRK01156  241 LNEL-SSLEDMKNRYESEIKTAESD-LSMELEKNNYYKELEERHmKIINDPVYKNRNYINDYFKYKNDIENKKQILSNID 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1125 ANISATNAELSTvLEVLQAEKSE-----------TNHIFELFEMEADMNS-----ERLIEKV-----------TGIKEEL 1177
Cdd:PRK01156  319 AEINKYHAIIKK-LSVLQKDYNDyikkksryddlNNQILELEGYEMDYNSylksiESLKKKIeeyskniermsAFISEIL 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1178 KETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQEL------------------QDSVKQKEEL 1239
Cdd:PRK01156  398 KIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgttlgeeksNHIINHYNEK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1240 VQNLEEKVREsssiIEAQNTKLNESNVQLENKTSCLK-------ETQDQLLESQKKE-KQLQEEAAKLSGELQQVQEANG 1311
Cdd:PRK01156  478 KSRLEEKIRE----IEIEVKDIDEKIVDLKKRKEYLEseeinksINEYNKIESARADlEDIKIKINELKDKHDKYEEIKN 553

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1312 DIKDslVKVEELVKVLEE--KLQAATSQLDAQ------QATNKELQELLVKSQENEGNLQGESLAVTEKLQQLE------ 1377
Cdd:PRK01156  554 RYKS--LKLEDLDSKRTSwlNALAVISLIDIEtnrsrsNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIEneannl 631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1378 -------QANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1450
Cdd:PRK01156  632 nnkyneiQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRI 711

                         570
                  ....*....|....*.
gi 24584806  1451 EELQKSLQQKQLLLEK 1466
Cdd:PRK01156  712 NELSDRINDINETLES 727
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 671-906 6.71e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 6.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  671 TLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDF---Q 747
Cdd:COG3883   16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  748 KKQSESEVHLQEIKAQNTQKDFelVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES 827
Cdd:COG3883   96 YRSGGSVSYLDVLLGSESFSDF--LDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806  828 ESALKVVQVQLEQLqqqaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSG 906
Cdd:COG3883  174 EAQQAEQEALLAQL-----------SAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 241
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 400-774 6.89e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.66  E-value: 6.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   400 QLQKNINELKARIVE-LESALD--NERKKTEElqcSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLvsatpslqsilP 476
Cdd:PRK10929   34 QAKAAKTPAQAEIVEaLQSALNwlEERKGSLE---RAKQYQQVIDNFPKLSAELRQQLNNERDEPRSV-----------P 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   477 PDLPSDDgaLQEEIAKLQEKMTIQqkevesriAEQLEEEQ-RLRENVKYLNeQIATLQSELvskdealeKFSLSEcgIEN 555
Cdd:PRK10929  100 PNMSTDA--LEQEILQVSSQLLEK--------SRQAQQEQdRAREISDSLS-QLPQQQTEA--------RRQLNE--IER 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   556 LRRELELLKEEnekqaqEAQAEFTRKLAEKSVevlrlsselqnLKATSDSLESERVNKTDECEIlqteVRMRDE----QI 631
Cdd:PRK10929  159 RLQTLGTPNTP------LAQAQLTALQAESAA-----------LKALVDELELAQLSANNRQEL----ARLRSElakkRS 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   632 RELNQQLDEVTTQLNV--QKADSSALDDMLRLQKEGTEEKSTLLE--KTEKELVQSKEQAAKTLND-------------- 693
Cdd:PRK10929  218 QQLDAYLQALRNQLNSqrQREAERALESTELLAEQSGDLPKSIVAqfKINRELSQALNQQAQRMDLiasqqrqaasqtlq 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   694 --------KEQ-------------LEKQISDLKQLAEQEKLVREMTENAINQIQLEkESIEQQLALKQNELEDFQKKQSE 752
Cdd:PRK10929  298 vrqalntlREQsqwlgvsnalgeaLRAQVARLPEMPKPQQLDTEMAQLRVQRLRYE-DLLNKQPQLRQIRQADGQPLTAE 376

                         410       420
                  ....*....|....*....|...
gi 24584806   753 SEVHLQE-IKAQNtqkdfELVES 774
Cdd:PRK10929  377 QNRILDAqLRTQR-----ELLNS 394
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 795-1525 6.91e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.43  E-value: 6.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    795 LQAALEELKKEKETIIKekeqELQQLQSKSAESESALKVVQVQLEQLQQQAAAsgEEGSKtvaklhdeISQLKSQAEETQ 874
Cdd:pfam10174    1 LQAQLRDLQRENELLRR----ELDIKESKLGSSMNSIKTFWSPELKKERALRK--EEAAR--------ISVLKEQYRVTQ 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    875 SELKSTQSNLEAKSKQLEAA---NGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHtdvESKTKQLEAANAALEKVN 951
Cdd:pfam10174   67 EENQHLQLTIQALQDELRAQrdlNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEH---ERQAKELFLLRKTLEEME 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    952 KEYAESRAEASDLQDKVKEITDTLHaelqaerssSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQ 1031
Cdd:pfam10174  144 LRIETQKQTLGARDESIKKLLEMLQ---------SKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREE 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1032 ---LQDSQDSQTKLKA------EGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKM 1102
Cdd:pfam10174  215 lhrRNQLQPDPAKTKAlqtvieMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQL 294

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1103 ASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNhifeLFEMEADMNSERLIEKVTgikeelkethl 1182
Cdd:pfam10174  295 KQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAA----ILQTEVDALRLRLEEKES----------- 359

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1183 QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVR---ESSSIIEAQNT 1259
Cdd:pfam10174  360 FLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKslqTDSSNTDTALT 439

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1260 KLNESNVQLENKTSCLKETQDQL-------LESQKKE-KQLQEEAAKLSGELQQ-------VQEANGDIKDSLVKVEELV 1324
Cdd:pfam10174  440 TLEEALSEKERIIERLKEQREREdrerleeLESLKKEnKDLKEKVSALQPELTEkesslidLKEHASSLASSGLKKDSKL 519

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1325 KVLEEKLQAATSQLDAQQATNKELQELLVKSQENEgnlqgeslAVTEKLQQLEQANGELKE--ALCQKE-----NGLKEL 1397
Cdd:pfam10174  520 KSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNP--------EINDRIRLLEQEVARYKEesGKAQAEverllGILREV 591

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1398 QG-KLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLllekgnefDTQLAE 1476
Cdd:pfam10174  592 ENeKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQL--------EELMGA 663

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 24584806   1477 YQKVIDEMDDAASVKSALLEQLQNRVAELeTALRQANDAQKTAYLETKE 1525
Cdd:pfam10174  664 LEKTRQELDATKARLSSTQQSLAEKDGHL-TNLRAERRKQLEEILEMKQ 711
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1334-1519 7.70e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 7.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1334 ATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKK 1413
Cdd:COG3883   14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1414 S----------------HNEIQDKLEQAQQKERtLQEETSKLAEQLSQLKQANEELQKSLQQKQlllekgNEFDTQLAEY 1477
Cdd:COG3883   94 AlyrsggsvsyldvllgSESFSDFLDRLSALSK-IADADADLLEELKADKAELEAKKAELEAKL------AELEALKAEL 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 24584806 1478 QKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1519
Cdd:COG3883  167 EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAA 208
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 631-1011 7.80e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 44.23  E-value: 7.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   631 IRELNQQLDEVTTQLNVqkadsSALDDMLRLQKEGTEEKSTLLEKTEKELvqSKEQAAKTLNDKEQLEKQISDL-KQLAE 709
Cdd:NF033838   71 LSEIQKSLDKRKHTQNV-----ALNKKLSDIKTEYLYELNVLKEKSEAEL--TSKTKKELDAAFEQFKKDTLEPgKKVAE 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   710 QEKLVREMTENAINQIQlEKESIEQQLALKQNELE--DFQKKQSESEVHLQEIKAQNTQKDfelvesgESLKKLQQQLEQ 787
Cdd:NF033838  144 ATKKVEEAEKKAKDQKE-EDRRNYPTNTYKTLELEiaESDVEVKKAELELVKEEAKEPRDE-------EKIKQAKAKVES 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   788 KtlgheklQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLK 867
Cdd:NF033838  216 K-------KAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDS 288

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   868 SQAEET--QSELKSTQSNLEAKSKQLEAangslEEEAKksghlleqitKLKSEVGETQAALSSCHTDVESKTKQLEAANA 945
Cdd:NF033838  289 SVGEETlpSPSLKPEKKVAEAEKKVEEA-----KKKAK----------DQKEEDRRNYPTNTYKTLELEIAESDVKVKEA 353

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24584806   946 ALEKVNKEYAESRAEasdlqDKVKEItdtlhaelQAERSSSSALHTKLSKFSDEIATGHKELTSKA 1011
Cdd:NF033838  354 ELELVKEEAKEPRNE-----EKIKQA--------KAKVESKKAEATRLEKIKTDRKKAEEEAKRKA 406
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
485-872 8.24e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 8.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  485 ALQEEIAKLQEkmtiQQKEVESRIAEQLEEEQRLRENVKYLN--EQIATLQSELVSKDEALEKFSLSECGIENLRRELEL 562
Cdd:COG4717   92 ELQEELEELEE----ELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEE 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  563 LKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVR---------MRDEQIRE 633
Cdd:COG4717  168 LEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEqleneleaaALEERLKE 247

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  634 LNQQLDEVTTQLNVQKADSSALDDMLRLQK--------------EGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEK 699
Cdd:COG4717  248 ARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvlgllallflLLAREKASLGKEAEELQALPALEELEEEELEELLAA 327

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  700 -QISDLKQLAEQEKLVREMTEnaINQIQLEKESIEQQLALKQNELE---DFQKKQSESEVHLQEiKAQNTQKDFELVesg 775
Cdd:COG4717  328 lGLPPDLSPEELLELLDRIEE--LQELLREAEELEEELQLEELEQEiaaLLAEAGVEDEEELRA-ALEQAEEYQELK--- 401

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  776 ESLKKLQQQLEQKTLGHEKLQAAL--EELKKEKETI---IKEKEQELQQLQSKSAESESALKVVqvqleqlqqqaaasge 850
Cdd:COG4717  402 EELEELEEQLEELLGELEELLEALdeEELEEELEELeeeLEELEEELEELREELAELEAELEQL---------------- 465

                        410       420
                 ....*....|....*....|..
gi 24584806  851 EGSKTVAKLHDEISQLKSQAEE 872
Cdd:COG4717  466 EEDGELAELLQELEELKAELRE 487
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1095-1567 8.26e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.04  E-value: 8.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1095 ELQHKEKMASEDAQKIADLKTLVEAIQvananisATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIK 1174
Cdd:pfam10174   40 ELKKERALRKEEAARISVLKEQYRVTQ-------EENQHLQLTIQALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPE 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1175 EELKETHLQLDERQKKFEELEekLKQAQQSEQKLQQESQtsKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1254
Cdd:pfam10174  113 LTEENFRRLQSEHERQAKELF--LLRKTLEEMELRIETQ--KQTLGARDESIKKLLEMLQSKGLPKKSGEEDWERTRRIA 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1255 EAQnTKLNESNVQLENKTsclKETQdQLLESQKKEKQLQEEAAKLSGeLQQVQEAN----GDIKDSLVKVEELVKVLE-- 1328
Cdd:pfam10174  189 EAE-MQLGHLEVLLDQKE---KENI-HLREELHRRNQLQPDPAKTKA-LQTVIEMKdtkiSSLERNIRDLEDEVQMLKtn 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1329 -----EKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGE-------LKEALCQKENGLKE 1396
Cdd:pfam10174  263 gllhtEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDckqhievLKESLTAKEQRAAI 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1397 LQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQkqlLLEKGNEFDTQLAE 1476
Cdd:pfam10174  343 LQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIEN---LQEQLRDKDKQLAG 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1477 YQKVIDE--------------MDDAASVKSALLEQLQNRVAELETALRQANDAQKTaylETKELRRQLESLE---LEKSR 1539
Cdd:pfam10174  420 LKERVKSlqtdssntdtalttLEEALSEKERIIERLKEQREREDRERLEELESLKK---ENKDLKEKVSALQpelTEKES 496

                          490       500
                   ....*....|....*....|....*....
gi 24584806   1540 EVLSLKAQMNGASSRSGKGD-EVESLDIE 1567
Cdd:pfam10174  497 SLIDLKEHASSLASSGLKKDsKLKSLEIA 525
COG4487 COG4487
Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];
668-828 9.00e-04

Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];


Pssm-ID: 443580 [Multi-domain]  Cd Length: 425  Bit Score: 43.78  E-value: 9.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  668 EKSTLLEKTEKELVQSKEQAAKTLNDK-EQLEKQISDLKQ-----LAEQEKLVREMTENAINQIQLEKESIEQQLALKQN 741
Cdd:COG4487   37 ERLADAAKREAALELAEAKAKAQLQEQvAEKDAEIAELRArleaeERKKALAVAEEKEKELAALQEALAEKDAKLAELQA 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  742 ELEDFQKKQSESEVHLQEIKAQnTQKdfELVESGESLK-KLQQQLEQKTLGHEKLQAA-----LEELKKEKETIIKEKEQ 815
Cdd:COG4487  117 KELELLKKERELEDAKREAELT-VEK--ERDEELDELKeKLKKEEEEKQLAEKSLKVAeyekqLKDMQEQIEELKRKKEQ 193

                        170
                 ....*....|...
gi 24584806  816 ELQQLQSKSAESE 828
Cdd:COG4487  194 GSTQLQGEVLELE 206
ClyA-like cd21116
family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including ...
 1197-1345 9.41e-04

family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including Bacillus cereus HblB, Aeromonas hydrophila AhlB, Bacillus thuringiensis Cry6Aa and similar proteins; This family belongs to the ClyA family of alpha-PFT bacterial toxins. PFTs form the major group of virulence factors in many pathogenic bacteria and in general are critical components of the molecular offensive and defensive machinery of cells in all kingdoms of life. Bacterial PFTs facilitate the takeover of host resources by puncturing holes in the membrane. PFTs can be classified as alpha-PFTs and beta-PFTs depending on the secondary structures of their membrane component. Alpha-PFTs use a ring of amphipathic helices while beta-PFTs use a beta-barrel to construct the pore. Members of this family include the toxins: Bacillus cereus hemolysin binding component B (HblB or HBL-B) of the diarrheal enterotoxin hemolysin BL, Aeromonas hydrophila hemolytic (Ahl) component B (AhlB) of the tripartite AhlABC toxin, Vibrio cholerae cytotoxin motility associated killing factor A (MakA) cytotoxin, Xenorhabdus nematophila alpha-xenorhabdolysin (XaxA), Bacillus thuringiensis crystal 6Aa (Cry6Aa) parasporal crystal (Cry) toxin, and Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA) of the non-hemolytic enterotoxin Nhe, which, despite its name, is hemolytic, among others. In solution, ClyA proteins have an elongated, almost entirely alpha-helical structure, except for a short hydrophobic beta-hairpin known as the beta-tongue. Pore formation by ClyA requires circular oligomerization of the toxin by a sequential mechanism. This, in turn, concentrates the amphipathic helices in the center of the ring-like structure, forming a helical barrel that inserts into the membrane by a wedge-like mechanism. Compared with ClyA, NheA is almost entirely alpha-helical with an enlarged "head" domain, and an enlarged beta-tongue; it has been proposed that NheA could even form beta-barrel pores. Alpha-PFTs with similar structures are increasingly being found in eukaryotes, in particular as components of the immune systems of animals. This family may be distantly related to Escherichia coli alpha-PFT hemolysin E (HlyE, also known as ClyA or SheA).


Pssm-ID: 439149 [Multi-domain]  Cd Length: 224  Bit Score: 42.79  E-value: 9.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1197 KLKQAQQSEQKLQQESQTSKEKLteiQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLK 1276
Cdd:cd21116   74 YYPDLIELADNLIKGDQGAKQQL---LQGLEALQSQVTKKQTSVTSFINELTTFKNDLDDDSRNLQTDATKAQAQVAVLN 150

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806 1277 ETQDQLlesqkkeKQLQEEAAKLSGELQQVQEANGDIKDSLvkveelvKVLEEKLQAATSQLDAQQATN 1345
Cdd:cd21116  151 ALKNQL-------NSLAEQIDAAIDALEKLSNDWQTLDSDI-------KELITDLEDAESSIDAAFLQA 205
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
629-1230 1.21e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  629 EQIRELNQQLDEVTTQLNVQKAdssaLDDMLRLQKEgtEEKSTLLEKtekELVQSKEQAAKTLNDKEQLEKQISDLKQLA 708
Cdd:COG4913  255 EPIRELAERYAAARERLAELEY----LRAALRLWFA--QRRLELLEA---ELEELRAELARLEAELERLEARLDALREEL 325

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  709 EQeklvremTENAINQIQLE-KESIEQQLALKQNELEDFQKKQSESEVHLQEIkaqntqkDFELVESGESLKKLQQQLEQ 787
Cdd:COG4913  326 DE-------LEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAAL-------GLPLPASAEEFAALRAEAAA 391

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  788 KTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvqvqleqlqqqaaasgeeGSKTVAKLHDEISQLK 867
Cdd:COG4913  392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR---------------------KSNIPARLLALRDALA 450

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  868 SQAEETQSELK------------------------STQSNLEAKSKQLEAANGSLE----------EEAKKSGHLLEQIT 913
Cdd:COG4913  451 EALGLDEAELPfvgelievrpeeerwrgaiervlgGFALTLLVPPEHYAAALRWVNrlhlrgrlvyERVRTGLPDPERPR 530

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  914 --------KLKSEVGETQAALSS---------CHTDVE--------------------------------------SKTK 938
Cdd:COG4913  531 ldpdslagKLDFKPHPFRAWLEAelgrrfdyvCVDSPEelrrhpraitragqvkgngtrhekddrrrirsryvlgfDNRA 610

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  939 QLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSS-----ALHTKLSKFSDEIAtghkeltsKADA 1013
Cdd:COG4913  611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeidvaSAEREIAELEAELE--------RLDA 682

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1014 WSQEMLQKEKELQELRQQLQDSQDSQTKLKaegeRKEKSFEESIKNLQEEVTKAKTENLEL-STGTQTTIKDLQERLEIT 1092
Cdd:COG4913  683 SSDDLAALEEQLEELEAELEELEEELDELK----GEIGRLEKELEQAEEELDELQDRLEAAeDLARLELRALLEERFAAA 758

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1093 NAELQHKEKMASedaqkiadlktLVEAIQVANANISATNAELSTVLEVLQAEksetnHIFELFEMEADMNSerlIEKVTG 1172
Cdd:COG4913  759 LGDAVERELREN-----------LEERIDALRARLNRAEEELERAMRAFNRE-----WPAETADLDADLES---LPEYLA 819

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1173 IKEELKETHLQldERQKKFEELEEKLKQAQQSE--QKLQQESQTSKEKLTEIQQSLQELQ 1230
Cdd:COG4913  820 LLDRLEEDGLP--EYEERFKELLNENSIEFVADllSKLRRAIREIKERIDPLNDSLKRIP 877
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1221-1448 1.25e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 43.08  E-value: 1.25e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    1221 EIQQ-SLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQlLESQK-----KEKQLQE 1294
Cdd:smart00787   66 ELYQfSCKELKKYISEGRDLFKEIEEETLINNPPLFKEYFSASPDVKLLMDKQFQLVKTFAR-LEAKKmwyewRMKLLEG 144

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    1295 EAAKLSGELQQVQEAngdiKDSLVKVEELVKVLEEKLQaatsqlDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQ 1374
Cdd:smart00787  145 LKEGLDENLEGLKED----YKLLMKELELLNSIKPKLR------DRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLK 214

                           170       180       190       200       210       220       230
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24584806    1375 QLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTlqeETSKLAEQLSQLKQ 1448
Cdd:smart00787  215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFK---EIEKLKEQLKLLQS 285
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 373-680 1.33e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.47  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    373 LREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKE 452
Cdd:TIGR04523  396 LESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    453 KI----HDLESKITKLVSATPSLQSilppdlpsddgaLQEEIAKLQEKmtiqQKEVESRIAEQLEEEQRLRENVKYLNEQ 528
Cdd:TIGR04523  476 SInkikQNLEQKQKELKSKEKELKK------------LNEEKKELEEK----VKDLTKKISSLKEKIEKLESEKKEKESK 539

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    529 IATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAqeAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLES 608
Cdd:TIGR04523  540 ISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKK--KQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEK 617

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24584806    609 ERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKEL 680
Cdd:TIGR04523  618 ELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKEL 689
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 665-822 1.39e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 43.48  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    665 GTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvremTENAINQIQLEKESIEQQLALK----- 739
Cdd:pfam05667  322 KVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQ-------VEEELEELKEQNEELEKQYKVKkktld 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    740 -----QNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKL--------QQQLEQKTLGHEKLQAALEELKKek 806
Cdd:pfam05667  395 llpdaEENIAKLQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEAksnkedesQRKLEEIKELREKIKEVAEEAKQ-- 472

                          170
                   ....*....|....*.
gi 24584806    807 etiikeKEQELQQLQS 822
Cdd:pfam05667  473 ------KEELYKQLVA 482
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-118 1.47e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806     2 SDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPqpskmkAPSSFGSTGSVSKIGRPCCNHTTP 81
Cdd:PHA03307  280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST------SSSSESSRGAAVSPGPSPSRSPSP 353

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 24584806    82 KSGPPPREATSMSRESDDNLSSINSAYTDNSSAVLTA 118
Cdd:PHA03307  354 SRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRA 390
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1181-1284 1.54e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.53  E-value: 1.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1181 HLQLDERQKKFEELEEKLKQAQQSEQKLQQESQT-SKEKLTEIQQSLQELQ---DSVKQKEELVQNLEEKVRESSSIIEA 1256
Cdd:COG0542  403 RMEIDSKPEELDELERRLEQLEIEKEALKKEQDEaSFERLAELRDELAELEeelEALKARWEAEKELIEEIQELKEELEQ 482

                         90       100
                 ....*....|....*....|....*...
gi 24584806 1257 QNTKLNESNVQLENKTSCLKETQDQLLE 1284
Cdd:COG0542  483 RYGKIPELEKELAELEEELAELAPLLRE 510
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 598-1504 1.54e-03

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 43.67  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   598 NLKATSDSLESERVNKtdecEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEkstllEKTE 677
Cdd:PTZ00440  881 IIKTLNIAINRSNSNK----QLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNEKLNLLNNLNKEKEKIEK-----QLSD 951

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   678 KELVQSKEQAAKTLNDKEQLEKQISDlKQLAEQEKLVREMTENAINQIQLEKESIEQQLAlkQNELEDFQKKQSESEVHL 757
Cdd:PTZ00440  952 TKINNLKMQIEKTLEYYDKSKENING-NDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNIL--NKKIDDLIKKQHDDIIEL 1028

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   758 ---------QEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETI---IKEKEQELQQLQSKSA 825
Cdd:PTZ00440 1029 idklikekgKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALlkkIDENKNKLIEIKNKSH 1108

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   826 ESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEisqLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKS 905
Cdd:PTZ00440 1109 EHVVNADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKE---LENMNLEDITLNEVNEIEIEYERILIDHIVEQINNEAKKS 1185

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   906 GHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAL---EKVNKEYAESR-----AEASDLQDKVKEITDTLHA 977
Cdd:PTZ00440 1186 KTIMEEIESYKKDIDQVKKNMSKERNDHLTTFEYNAYYDKATasyENIEELTTEAKglkgeANRSTNVDELKEIKLQVFS 1265

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   978 ELQAERSSSSALHTKLSkfsdEIATGHKELTS-KADAWSQEMLQKEKELQELrqqlqdsqdsqtKLKAEGERKEKSfeES 1056
Cdd:PTZ00440 1266 YLQQVIKENNKMENALH----EIKNMYEFLISiDSEKILKEILNSTKKAEEF------------SNDAKKELEKTD--NL 1327

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1057 IKNLQEEVTKAKTENLELSTgtqtTIKDLQERLEITNAELQHKEKMASEDA-----QKIADLKTLVEaIQVANANISATN 1131
Cdd:PTZ00440 1328 IKQVEAKIEQAKEHKNKIYG----SLEDKQIDDEIKKIEQIKEEISNKRKEinkylSNIKSNKEKCD-LHVRNASRGKDK 1402

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1132 AELSTVLEVLQAEKSETNHIFELFEMeadmnserlIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQE 1211
Cdd:PTZ00440 1403 IDFLNKHEAIEPSNSKEVNIIKITDN---------INKCKQYSNEAMETENKADENNDSIIKYEKEITNILNNSSILGKK 1473

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1212 SQTSKEK------LTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLES 1285
Cdd:PTZ00440 1474 TKLEKKKkeatniMDDINGEHSIIKTKLTKSSEKLNQLNEQPNIKREGDVLNNDKSTIAYETIQYNLGRVKHNLLNILNI 1553

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1286 QKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVK------VEELVKVLEEK--LQAATSQLDAQQATNKELQELLVKSQE 1357
Cdd:PTZ00440 1554 KDEIETILNKAQDLMRDISKISKIVENKNLENLNdkeadyVKYLDNILKEKqlMEAEYKKLNEIYSDVDNIEKELKKHKK 1633

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1358 N--EGNLQgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLD----ESNTVLESQKKSHNEIQDKLEQAQQKERT 1431
Cdd:PTZ00440 1634 NyeIGLLE----KVIEINKNIKLYMDSTKESLNSLVNNFSSLFNNFYlnkyNINENLEKYKKKLNEIYNEFMESYNIIQE 1709

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24584806  1432 LQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF--DTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAE 1504
Cdd:PTZ00440 1710 KMKEVSNDDVDYNEAKTLREEAQKEEVNLNNKEEEAKKYlnDIKKQESFRFILYMKEKLDELSKMCKQQYNIVDE 1784
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1372-1519 1.58e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1372 KLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQE--ETSKLAEQLSQLKQA 1449
Cdd:COG1579   18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlGNVRNNKEYEALQKE 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806 1450 NEELQKSLQQ-KQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1519
Cdd:COG1579   98 IESLKRRISDlEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
Rabaptin pfam03528
Rabaptin;
1188-1540 1.68e-03

Rabaptin;


Pssm-ID: 367545 [Multi-domain]  Cd Length: 486  Bit Score: 42.79  E-value: 1.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1188 QKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSlqelqdsvkqKEELVQNLEEKVRESSSIIEAQNTKLNESNVQ 1267
Cdd:pfam03528    7 QQRVAELEKENAEFYRLKQQLEAEFNQKRAKFKELYLA----------KEEDLKRQNAVLQEAQVELDALQNQLALARAE 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1268 LENKTSCLKETQDQLLES-QKKEKQLQEEAAKLSGELqqvqeangdiKDSLVKVEELVKVLEEKLQAATSQL-DAQQATN 1345
Cdd:pfam03528   77 MENIKAVATVSENTKQEAiDEVKSQWQEEVASLQAIM----------KETVREYEVQFHRRLEQERAQWNQYrESAEREI 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1346 KELQELLVKSQENEgNLQGESLAVTEKLQQL-------EQANGELKEALCQKENGLKELQG-KLDESNTVLESQKKSHNE 1417
Cdd:pfam03528  147 ADLRRRLSEGQEEE-NLEDEMKKAQEDAEKLrsvvmpmEKEIAALKAKLTEAEDKIKELEAsKMKELNHYLEAEKSCRTD 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1418 iqdkleqaqqkertLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAE-YQKVIDEMDDAASVksaLLE 1496
Cdd:pfam03528  226 --------------LEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHtWQKANDQFLESQRL---LMR 288

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 24584806   1497 QLQNRVAELET-ALRQANDAQKTAYLETKELRRQLESLELEKSRE 1540
Cdd:pfam03528  289 DMQRMESVLTSeQLRQVEEIKKKDQEEHKRARTHKEKETLKSDRE 333
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1079-1309 1.69e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 1.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1079 QTTIKDLQERLEITNA------ELqhkeKMASEDAQKIAD-LKTLVEA-----IQVANANISATNAELSTVLEVLQAEKS 1146
Cdd:COG3206  117 EAAIERLRKNLTVEPVkgsnviEI----SYTSPDPELAAAvANALAEAyleqnLELRREEARKALEFLEEQLPELRKELE 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1147 ETNHIFELFE-----MEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLK--------------------QA 1201
Cdd:COG3206  193 EAEAALEEFRqknglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGsgpdalpellqspviqqlraQL 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1202 QQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQ 1281
Cdd:COG3206  273 AELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAE 352

                        250       260
                 ....*....|....*....|....*...
gi 24584806 1282 LLESQKKEKQLQEEAAKLSGELQQVQEA 1309
Cdd:COG3206  353 LRRLEREVEVARELYESLLQRLEEARLA 380
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1290-1598 2.00e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.02  E-value: 2.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1290 KQLQEEAAKLSGELQQVQEANGDIKDSLVkveELVKVLEEkLQAATSQLDAQ-QATNKELqellvksqenegNLQGESLA 1368
Cdd:COG3096  281 RELSERALELRRELFGARRQLAEEQYRLV---EMARELEE-LSARESDLEQDyQAASDHL------------NLVQTALR 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1369 VTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEEtsklAEQLSQLKQ 1448
Cdd:COG3096  345 QQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTR----AIQYQQAVQ 420

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1449 ANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE-----------MDDAASVKSALLEQLQNRVAELETA--------- 1508
Cdd:COG3096  421 ALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEevleleqklsvADAARRQFEKAYELVCKIAGEVERSqawqtarel 500

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1509 LRQANDAQKTAYLETkELRRQLESLE--LEKSREVLSLKAQMNGASSRS-GKGDEVESL------DIETSLAKINFLNSI 1579
Cdd:COG3096  501 LRRYRSQQALAQRLQ-QLRAQLAELEqrLRQQQNAERLLEEFCQRIGQQlDAAEELEELlaeleaQLEELEEQAAEAVEQ 579

                        330
                 ....*....|....*....
gi 24584806 1580 IADMQQKNDALKAKVQTLE 1598
Cdd:COG3096  580 RSELRQQLEQLRARIKELA 598
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1112-1257 2.10e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 42.31  E-value: 2.10e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    1112 DLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNH-IFELFEMEADMNSERLIEkVTGIKEELKETHLQLDERQKK 1190
Cdd:smart00787  148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEeLRQLKQLEDELEDCDPTE-LDRAKEKLKKLLQEIMIKVKK 226

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584806    1191 FEELEEKLkqaqqseQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQ 1257
Cdd:smart00787  227 LEELEEEL-------QELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIEKLKEQLKLLQSL 286
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1158-1331 2.37e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 2.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1158 EADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEiqqsLQELQDSVKQKE 1237
Cdd:COG1579   14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKK----YEEQLGNVRNNK 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1238 ELvQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQvqeangDIKDSL 1317
Cdd:COG1579   90 EY-EALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA------ELEELE 162

                        170
                 ....*....|....
gi 24584806 1318 VKVEELVKVLEEKL 1331
Cdd:COG1579  163 AEREELAAKIPPEL 176
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
580-821 2.65e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 2.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  580 RKLAEKSVEVLRL--------SSELQNLKATSDSLESERVNKTDeceILQTEVRMRD-EQIRELNQQLDE--VTTQLNVQ 648
Cdd:COG3206   93 RPVLERVVDKLNLdedplgeeASREAAIERLRKNLTVEPVKGSN---VIEISYTSPDpELAAAVANALAEayLEQNLELR 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  649 KADSSALDDMLRLQKEGTEEKstlLEKTEKELV--QSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI- 725
Cdd:COG3206  170 REEARKALEFLEEQLPELRKE---LEEAEAALEefRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALr 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  726 -QLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLG--------HEKLQ 796
Cdd:COG3206  247 aQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRilasleaeLEALQ 326

                        250       260       270
                 ....*....|....*....|....*....|.
gi 24584806  797 AALEELKKEKETI------IKEKEQELQQLQ 821
Cdd:COG3206  327 AREASLQAQLAQLearlaeLPELEAELRRLE 357
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 624-828 2.80e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 2.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   624 VRMRDEQIRELNQQLDEVTTQLnvQKADSSALDDMLR-LQKEGTEEKSTLLEKTEKELVQ-----SKEQAAKTLN---DK 694
Cdd:PRK05771    4 VRMKKVLIVTLKSYKDEVLEAL--HELGVVHIEDLKEeLSNERLRKLRSLLTKLSEALDKlrsylPKLNPLREEKkkvSV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   695 EQLEKQISDLKQLAEQ-EKLVREMTENaINQIQLEKESIEQQLA--------------LKQNEL----------EDFQKK 749
Cdd:PRK05771   82 KSLEELIKDVEEELEKiEKEIKELEEE-ISELENEIKELEQEIErlepwgnfdldlslLLGFKYvsvfvgtvpeDKLEEL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   750 QSESEVHLQEIKAQNTQKDFELV--------ESGESLKKLQQQlEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQ 821
Cdd:PRK05771  161 KLESDVENVEYISTDKGYVYVVVvvlkelsdEVEEELKKLGFE-RLELEEEGTPSELIREIKEELEEIEKERESLLEELK 239


                  ....*..
gi 24584806   822 SKSAESE 828
Cdd:PRK05771  240 ELAKKYL 246
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 409-737 3.12e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 3.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   409 KARIVelesALDNERKKT-EELQcSIDEAQFCgdELNAQSQVykEKIHDLESKITKLVSATPSLQSILPPDlpsddGALQ 487
Cdd:PRK05771    8 KVLIV----TLKSYKDEVlEALH-ELGVVHIE--DLKEELSN--ERLRKLRSLLTKLSEALDKLRSYLPKL-----NPLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   488 EEIAKLQEKMTIQQKEVESRIAEQLEEEqrlrenVKYLNEQIATLQSELvskdEALEKfslsecgienlrrelellkeen 567
Cdd:PRK05771   74 EEKKKVSVKSLEELIKDVEEELEKIEKE------IKELEEEISELENEI----KELEQ---------------------- 121

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   568 ekqaqeaqaeftrklAEKSVEVLR-LSSELQNLKATSD-SLESERVNKTDECEILQTEVrmrDEQIRELNQQLDEVTTQL 645
Cdd:PRK05771  122 ---------------EIERLEPWGnFDLDLSLLLGFKYvSVFVGTVPEDKLEELKLESD---VENVEYISTDKGYVYVVV 183

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   646 NVQKADSSALDDMLRlqKEGTEEKSTLLEKTEKELVQSKEQAAKTLND-KEQLEKQISDLKQLAEQEKLVREmtenAINQ 724
Cdd:PRK05771  184 VVLKELSDEVEEELK--KLGFERLELEEEGTPSELIREIKEELEEIEKeRESLLEELKELAKKYLEELLALY----EYLE 257

                         330
                  ....*....|...
gi 24584806   725 IQLEKESIEQQLA 737
Cdd:PRK05771  258 IELERAEALSKFL 270
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 724-1055 3.24e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.19  E-value: 3.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    724 QIQLEKESIEQQLALKQNEL--EDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEE 801
Cdd:pfam07888   33 QNRLEECLQERAELLQAQEAanRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEE 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    802 LKKEKETIIKEKEQELQQLQsksaESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEisqlKSQAEETQSELKSTQ 881
Cdd:pfam07888  113 LSEEKDALLAQRAAHEARIR----ELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE----EAERKQLQAKLQQTE 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    882 SNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQ---AALSSCHTDVESKTKQLEAANAALEKVNKEYAEsr 958
Cdd:pfam07888  185 EELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHrkeAENEALLEELRSLQERLNASERKVEGLGEELSS-- 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    959 aeasdlqdkVKEITDTLHAELQAERSSSSALHTKLSKFSDeiatghkeltskadAWSQEMLQKEKELQELRQQLQDSQDS 1038
Cdd:pfam07888  263 ---------MAAQRDRTQAELHQARLQAAQLTLQLADASL--------------ALREGRARWAQERETLQQSAEADKDR 319

                          330
                   ....*....|....*..
gi 24584806   1039 QTKLKAEGERKEKSFEE 1055
Cdd:pfam07888  320 IEKLSAELQRLEERLQE 336
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 582-977 3.88e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 41.97  E-value: 3.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    582 LAEKSVEVLRLSselqnlkatsDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSsalddMLRL 661
Cdd:pfam13166   87 LGEESIEIQEKI----------AKLKKEIKDHEEKLDAAEANLQKLDKEKEKLEADFLDECWKKIKRKKNS-----ALSE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    662 QKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDkeqlEKQISDLKQLAEQEK-LVREMTENAINQIQLEKESI-EQQLALK 739
Cdd:pfam13166  152 ALNGFKYEANFKSRLLREIEKDNFNAGVLLSD----EDRKAALATVFSDNKpEIAPLTFNVIDFDALEKAEIlIQKVIGK 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    740 QNELEDFQKKQSESEvhlqeikaqntqkdfeLVESGESL-KKLQQQLE--QKTLGHEkLQAALEE------------LKK 804
Cdd:pfam13166  228 SSAIEELIKNPDLAD----------------WVEQGLELhKAHLDTCPfcGQPLPAE-RKAALEAhfddeftefqnrLQK 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    805 EKETIIKEKEQELQQLQSKSAESesalkvvqvqleqlqqqaaasgeegsKTVAKLHDEISQLKSQAEETQSELKSTQSNL 884
Cdd:pfam13166  291 LIEKVESAISSLLAQLPAVSDLA--------------------------SLLSAFELDVEDIESEAEVLNSQLDGLRRAL 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    885 EAKSKQ-------------LEAANGS-----------------LEEEAKKSGHLLEQ--ITKLKSEVGETQAALSSCHTD 932
Cdd:pfam13166  345 EAKRKDpfksieldsvdakIESINDLvasineliakhneitdnFEEEKNKAKKKLRLhlVEEFKSEIDEYKDKYAGLEKA 424

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 24584806    933 VESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHA 977
Cdd:pfam13166  425 INSLEKEIKNLEAEIKKLREEIKELEAQLRDHKPGADEINKLLKA 469
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 854-995 4.12e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 4.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  854 KTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHL--LEQITKLKSEVGETQAALSSCHT 931
Cdd:COG1579   31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnNKEYEALQKEIESLKRRISDLED 110

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24584806  932 DVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSK 995
Cdd:COG1579  111 EILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
GAS pfam13851
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ...
 1281-1460 4.18e-03

Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.


Pssm-ID: 464001 [Multi-domain]  Cd Length: 200  Bit Score: 40.27  E-value: 4.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1281 QLLESQKKE-KQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQaatsQLDAQQATNKELQELLVKSQENE 1359
Cdd:pfam13851   26 ELIKSLKEEiAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLE----NYEKDKQSLKNLKARLKVLEKEL 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1360 GNLQGESLAVTEKLQQLEQANGELKEalcQKENGLKELQGKLDESNTVLESQkkshneIQDKLEQAQQKERTLQEETSKL 1439
Cdd:pfam13851  102 KDLKWEHEVLEQRFEKVERERDELYD---KFEAAIQDVQQKTGLKNLLLEKK------LQALGETLEKKEAQLNEVLAAA 172

                          170       180
                   ....*....|....*....|.
gi 24584806   1440 AEQLSQLKQANEELQKSLQQK 1460
Cdd:pfam13851  173 NLDPDALQAVTEKLEDVLESK 193
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1347-1461 4.53e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 4.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1347 ELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDES-NTVLESQKKSHNEIQDKLEQA 1425
Cdd:PRK00409  517 KLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEaQQAIKEAKKEADEIIKELRQL 596

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 24584806  1426 QQKERTLQEEtSKLAEQLSQLKQANEELQKSLQQKQ 1461
Cdd:PRK00409  597 QKGGYASVKA-HELIEARKRLNKANEKKEKKKKKQK 631
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1043-1241 4.84e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 4.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1043 KAEGERKEKSFEESIKNLQEEVTKA-------KTENLELSTGTQTT-----IKDLQERLEITNAELQHKEKMASEDAQKI 1110
Cdd:COG3206  170 REEARKALEFLEEQLPELRKELEEAeaaleefRQKNGLVDLSEEAKlllqqLSELESQLAEARAELAEAEARLAALRAQL 249

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1111 ADLKTLVEAIQvANANISATNAELSTvLEVLQAEKSET---NH--IFELFEMEADMNS---ERLIEKVTGIKEELKETHL 1182
Cdd:COG3206  250 GSGPDALPELL-QSPVIQQLRAQLAE-LEAELAELSARytpNHpdVIALRAQIAALRAqlqQEAQRILASLEAELEALQA 327

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24584806 1183 QLDERQKKFEELEEKLKQAQQSEQK---LQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQ 1241
Cdd:COG3206  328 REASLQAQLAQLEARLAELPELEAElrrLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 394-670 4.85e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 4.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  394 AQNQALQLQKNINELKARIVELESALDNERKKTEELQcsideaqfcgdelnaqsqvykEKIHDLESKItklvsatpslqs 473
Cdd:COG4942   18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALL---------------------KQLAALERRI------------ 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  474 ilppdlpsddGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQselVSKDEALEKFSLSecgi 553
Cdd:COG4942   65 ----------AALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALY---RLGRQPPLALLLS---- 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  554 eNLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDEceiLQTEVRMRDEQIRE 633
Cdd:COG4942  128 -PEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAA---LEALKAERQKLLAR 203

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 24584806  634 LNQQLDEVTTQLNVQKADSSALDDML-RLQKEGTEEKS 670
Cdd:COG4942  204 LEKELAELAAELAELQQEAEELEALIaRLEAEAAAAAE 241
COG5391 COG5391
Phox homology (PX) domain protein [Intracellular trafficking and secretion / General function ...
 1150-1305 5.08e-03

Phox homology (PX) domain protein [Intracellular trafficking and secretion / General function prediction only];


Pssm-ID: 227680 [Multi-domain]  Cd Length: 524  Bit Score: 41.32  E-value: 5.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1150 HIFELFEMEAdMNSERLIEKVTGIKEELKETHLQ-LDERQ---KKFEELEEKLkqAQQSEQKLQQESQTSKEKLTEIQ-- 1223
Cdd:COG5391  301 SIFSLFEKIL-IQLESEEESLTRLLESLNNLLLLvLNFSGvfaKRLEQNQNSI--LNEGVVQAETLRSSLKELLTQLQde 377

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1224 -QSLQELQDSVKQKEELVQNLEEKVRESSSIiEAQNTKLNESNV-QLENKTSCLKETQD-----QLLESQKKEKQLQEEA 1296
Cdd:COG5391  378 iKSRESLILTDSNLEKLTDQNLEDVEELSRS-LRKNSSQRAVVSqQPEGLTSFSKLSYKlrdfvQEKSRSKSIESLQQDK 456


                 ....*....
gi 24584806 1297 AKLSGELQQ 1305
Cdd:COG5391  457 EKLEEQLAI 465
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 399-823 5.49e-03

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 41.21  E-value: 5.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    399 LQLQKNINELKARIVELESALDNERKKTEELQcsideaqfcgdelnaqsqvykEKIHDLESKITKLVSATPSLQsilppd 478
Cdd:pfam05622   62 LLLQKQLEQLQEENFRLETARDDYRIKCEELE---------------------KEVLELQHRNEELTSLAEEAQ------ 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    479 lpsddgALQEEIAKLQE---KMTIQQKEVESrIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIEN 555
Cdd:pfam05622  115 ------ALKDEMDILREssdKVKKLEATVET-YKKKLEDLGDLRRQVKLLEERNAEYMQRTLQLEEELKKANALRGQLET 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    556 lrrelellkeeNEKQAQEAQAeftrKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILqtevRMRDEQIRELN 635
Cdd:pfam05622  188 -----------YKRQVQELHG----KLSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERDTL----RETNEELRCAQ 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    636 QQLDEVTTQLNVQKADSSALDDMLR-LQKEGTEEKSTLLEKTEKELvqskeqaakTLNDKEQLEKQISDLKQLAEQeklv 714
Cdd:pfam05622  249 LQQAELSQADALLSPSSDPGDNLAAeIMPAEIREKLIRLQHENKML---------RLGQEGSYRERLTELQQLLED---- 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    715 remTENAINQIQLEKESIEQQLALKQNELEDFQKKQSEsevhlQEIKAQNT-QKDFELVESGESLKKLQQQLEQKTLGHE 793
Cdd:pfam05622  316 ---ANRRKNELETQNRLANQRILELQQQVEELQKALQE-----QGSKAEDSsLLKQKLEEHLEKLHEAQSELQKKKEQIE 387

                          410       420       430
                   ....*....|....*....|....*....|....
gi 24584806    794 KLQAALEELKKEK----ETIIKEKEQELQQLQSK 823
Cdd:pfam05622  388 ELEPKQDSNLAQKidelQEALRKKDEDMKAMEER 421
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1168-1415 5.57e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 41.57  E-value: 5.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1168 EKVTGIKEELKETHLQLDERQKK------FEELEEKLKQAQQSEQKLQQESQTSkEKLTEIQQSLQELQDSVKQKEELVQ 1241
Cdd:PTZ00108 1102 EKVEKLNAELEKKEKELEKLKNTtpkdmwLEDLDKFEEALEEQEEVEEKEIAKE-QRLKSKTKGKASKLRKPKLKKKEKK 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1242 NLEEKVRESSSIIEAQNTKLNESNVQLE-----NKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDS 1316
Cdd:PTZ00108 1181 KKKSSADKSKKASVVGNSKRVDSDEKRKlddkpDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEF 1260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  1317 LVKVEELVKVLEEKLQAATSQLDAQQATNKEL-QELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLK 1395
Cdd:PTZ00108 1261 SSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPdGESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTR 1340

                         250       260
                  ....*....|....*....|
gi 24584806  1396 ELQGKlDESNTVLESQKKSH 1415
Cdd:PTZ00108 1341 VKQAS-ASQSSRLLRRPRKK 1359
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
672-926 5.74e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.04  E-value: 5.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  672 LLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQS 751
Cdd:COG4372   18 LRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELA 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  752 ESEVHLQEIKAQNTQKDFELvesgESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAL 831
Cdd:COG4372   98 QAQEELESLQEEAEELQEEL----EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  832 KVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQ 911
Cdd:COG4372  174 QALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLE 253

                        250
                 ....*....|....*
gi 24584806  912 ITKLKSEVGETQAAL 926
Cdd:COG4372  254 EVILKEIEELELAIL 268
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 365-818 5.83e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.63  E-value: 5.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    365 SQFSMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELN 444
Cdd:pfam05483  209 ARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELI 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    445 AQSQVYKEKIHDLESKITKLVSATPSLQSILPP------DLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLE----E 514
Cdd:pfam05483  289 EKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIatkticQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEllrtE 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    515 EQRLRENvkylNEQIATLQSELVSKDEALEKFSlsecGIENLRRELELLKEENEKQAQeaqaeftrKLAEKSVEVLRLSS 594
Cdd:pfam05483  369 QQRLEKN----EDQLKIITMELQKKSSELEEMT----KFKNNKEVELEELKKILAEDE--------KLLDEKKQFEKIAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    595 ELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQireLNQQLDEVTTQLNVQKADSSALD---DMLRLQ-KEGTEEKS 670
Cdd:pfam05483  433 ELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEH---YLKEVEDLKTELEKEKLKNIELTahcDKLLLEnKELTQEAS 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    671 TL---LEKTEKELVQSKEQAAKTL-----------NDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQL 736
Cdd:pfam05483  510 DMtleLKKHQEDIINCKKQEERMLkqienleekemNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQM 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806    737 ALKQNELEDFQKKQSESEVHLQEIKAQNtqKDFELVESGESlkklqQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQE 816
Cdd:pfam05483  590 KILENKCNNLKKQIENKNKNIEELHQEN--KALKKKGSAEN-----KQLNAYEIKVNKLELELASAKQKFEEIIDNYQKE 662


                   ..
gi 24584806    817 LQ 818
Cdd:pfam05483  663 IE 664
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 1192-1466 5.93e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 41.28  E-value: 5.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1192 EELEEKLKQAQQSEqkLQQESQTSKEKLTEIQQSLQELQDSVKQK----EELVQNLEEK-VRESSSIIEAQN------TK 1260
Cdd:pfam07111  128 EMVRKNLEEGSQRE--LEEIQRLHQEQLSSLTQAHEEALSSLTSKaeglEKSLNSLETKrAGEAKQLAEAQKeaellrKQ 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1261 LNESNVQLENKTSCLKETQDQLLESQKKEKQLQE---EAAKLSGELQQVQEANGDIKDSL----VKVEELVKVL---EEK 1330
Cdd:pfam07111  206 LSKTQEELEAQVTLVESLRKYVGEQVPPEVHSQTwelERQELLDTMQHLQEDRADLQATVellqVRVQSLTHMLalqEEE 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806   1331 LQAATSQLDAQQAT-NKELQELLVKSQEN----EGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1405
Cdd:pfam07111  286 LTRKIQPSDSLEPEfPKKCRSLLNRWREKvfalMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKA 365

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584806   1406 TVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEK 1466
Cdd:pfam07111  366 AEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQ 426
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
387-606 6.19e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 6.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  387 RDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQcsideaqfcgdeLNAQSQVYKEKIHDLESKITKLVS 466
Cdd:COG3206  166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVD------------LSEEAKLLLQQLSELESQLAEARA 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  467 ATPSLQSILpPDLPSDDGALQEEIAKLQEKMTIQQ-----KEVESRIAEQLeeeQRLREN---VKYLNEQIATLQSELvs 538
Cdd:COG3206  234 ELAEAEARL-AALRAQLGSGPDALPELLQSPVIQQlraqlAELEAELAELS---ARYTPNhpdVIALRAQIAALRAQL-- 307

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584806  539 KDEALEKFSlsecGIENLRRELELLKEENEKQAQEAQAEFtRKLAEKSVEVLRLSSELQNLKATSDSL 606
Cdd:COG3206  308 QQEAQRILA----SLEAELEALQAREASLQAQLAQLEARL-AELPELEAELRRLEREVEVARELYESL 370
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 894-1133 6.30e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 6.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  894 ANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITd 973
Cdd:COG3883   14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERA- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  974 tlhAELQAERSSSSALHTKLSkfsdeiATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSf 1053
Cdd:COG3883   93 ---RALYRSGGSVSYLDVLLG------SESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL- 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1054 EESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAE 1133
Cdd:COG3883  163 KAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 242
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 911-1089 7.80e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 7.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  911 QITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHA-----ELQAerss 985
Cdd:COG1579   18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrnnkEYEA---- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  986 ssalhtklskFSDEIATGHKELTSKADawsqEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVT 1065
Cdd:COG1579   94 ----------LQKEIESLKRRISDLED----EILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELE 159

                        170       180
                 ....*....|....*....|....
gi 24584806 1066 KAKTENLELSTGTQTTIKDLQERL 1089
Cdd:COG1579  160 ELEAEREELAAKIPPELLALYERI 183
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 581-791 8.38e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 8.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  581 KLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKAdssALDDMLR 660
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE---ELGERAR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806  661 -LQKEGTEEK--STLLEKTEKELVQSKEQAAKTL--NDKEQLEKQISDLKQLAEQEKLVRE---MTENAINQIQLEKESI 732
Cdd:COG3883   94 aLYRSGGSVSylDVLLGSESFSDFLDRLSALSKIadADADLLEELKADKAELEAKKAELEAklaELEALKAELEAAKAEL 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 24584806  733 EQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLG 791
Cdd:COG3883  174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1184-1599 9.92e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 40.71  E-value: 9.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1184 LDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQqSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNE 1263
Cdd:COG5185   92 KKLDTKILQEYVNSLIKLPNYEWSADILISLLYLYKSEIV-ALKDELIKVEKLDEIADIEASYGEVETGIIKDIFGKLTQ 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1264 SNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQA 1343
Cdd:COG5185  171 ELNQNLKKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQ 250

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1344 TNKELQELLVKSQENEGNLQGESlavTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHneiqdKLE 1423
Cdd:COG5185  251 TSDKLEKLVEQNTDLRLEKLGEN---AESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLA-----AAE 322

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1424 QAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEkGNEFDTQLAEYQKVIDEMDDA-ASVKSALLEQLQNRV 1502
Cdd:COG5185  323 AEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIE-NIVGEVELSKSSEELDSFKDTiESTKESLDEIPQNQR 401

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584806 1503 AELETALRQANDAQKTAYLETKELRRQLESL------------ELEKSREVLSLKAQMNGASSRSGKGDEVESldieTSL 1570
Cdd:COG5185  402 GYAQEILATLEDTLKAADRQIEELQRQIEQAtssneevskllnELISELNKVMREADEESQSRLEEAYDEINR----SVR 477

                        410       420
                 ....*....|....*....|....*....
gi 24584806 1571 AKINFLNSIIADMQQKNDALKAKVQTLET 1599
Cdd:COG5185  478 SKKEDLNEELTQIESRVSTLKATLEKLRA 506
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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