|
Name |
Accession |
Description |
Interval |
E-value |
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
23-414 |
3.05e-66 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 218.54 E-value: 3.05e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 23 APNILNLGVGAPGPDILTAncDSFRTATDHCLerekRENQSLIFQYGPTSGTFEVRREISTYFTEMfksPVNC--EDLII 100
Cdd:COG1167 105 APGVIDLGSGAPDPDLFPL--AALRRALRRAL----RRLPPALLGYGDPQGLPELREAIARYLARR---GVPAspDQILI 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 101 TTGASHGLHILLSTMLDFEGFVFVDEYTYMIALDSIKHFStVTIVPVKLNDDGVDLKDLEEKVSKRRFQskkkefwgIYY 180
Cdd:COG1167 176 TSGAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAG-LRLVPVPVDEDGLDLDALEAALRRHRPR--------AVY 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 181 TIPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPtHSRLLSYDDrndanfAGHVISNGSFSKILGPG 260
Cdd:COG1167 247 VTPSHQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRP-PPPLAALDA------PGRVIYIGSFSKTLAPG 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 261 VRLGWLEVPPRLKPILDGSGFATSGGcfnnyTSG----IVGSLFELKLAQKQISESYEAYKERMLATTQVLRDELPDCCK 336
Cdd:COG1167 320 LRLGYLVAPGRLIERLARLKRATDLG-----TSPltqlALAEFLESGHYDRHLRRLRREYRARRDLLLAALARHLPDGLR 394
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21356535 337 LVSPTGGYFIWVRIPDRLDCREFLKYCMEnHKIYFIVGTRFSADGQSGkQFFRLSIAFYPKSKLVDGARRLCNALKDY 414
Cdd:COG1167 395 VTGPPGGLHLWLELPEGVDAEALAAAALA-RGILVAPGSAFSADGPPR-NGLRLGFGAPSEEELEEALRRLAELLREL 470
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
27-407 |
1.61e-62 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 205.27 E-value: 1.61e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 27 LNLGVGAPgpdiltancdSFRTATDHCLEREKRENQSLIFQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGASH 106
Cdd:cd00609 1 IDLSIGEP----------DFPPPPEVLEALAAAALRAGLLGYYPDPGLPELREAIAEWLGRRGGVDVPPEEIVVTNGAQE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 107 GLHILLSTMLDFEGFVFVDEYTYMIALDSIKHFStVTIVPVKLNDDGVDLKDLEEkvskrrFQSKKKEFWGIYYTIPtYH 186
Cdd:cd00609 71 ALSLLLRALLNPGDEVLVPDPTYPGYEAAARLAG-AEVVPVPLDEEGGFLLDLEL------LEAAKTPKTKLLYLNN-PN 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 187 NPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSRLLSYDDrndanfaGHVISNGSFSKILG-PGVRLGW 265
Cdd:cd00609 143 NPTGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALALLDAY-------ERVIVLRSFSKTFGlPGLRIGY 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 266 LEVPPRLkpILDGSGFATSGGCFNNYTSGIVGSLFELKLAQKQISESYEAYKERMLATTQVLRDELPDCCklVSPTGGYF 345
Cdd:cd00609 216 LIAPPEE--LLERLKKLLPYTTSGPSTLSQAAAAAALDDGEEHLEELRERYRRRRDALLEALKELGPLVV--VKPSGGFF 291
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 21356535 346 IWVRIPDRLDcREFLKYCMENHKIYFIVGTRFsadGQSGKQFFRLSIAfYPKSKLVDGARRL 407
Cdd:cd00609 292 LWLDLPEGDD-EEFLERLLLEAGVVVRPGSAF---GEGGEGFVRLSFA-TPEEELEEALERL 348
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
24-414 |
2.00e-45 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 161.45 E-value: 2.00e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 24 PNILNLGVGAPgpDILTAncDSFRTATDHCLEREKrenqsliFQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTG 103
Cdd:COG0436 30 EDVIDLGIGEP--DFPTP--DHIREAAIEALDDGV-------TGYTPSAGIPELREAIAAYYKRRYGVDLDPDEILVTNG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 104 ASHGLHILLSTMLDfEGfvfvDE----------YTYMIALDSikhfstVTIVPVKLN-DDG--VDLKDLEEKVSKRrfqS 170
Cdd:COG0436 99 AKEALALALLALLN-PG----DEvlvpdpgypsYRAAVRLAG------GKPVPVPLDeENGflPDPEALEAAITPR---T 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 171 KkkefwGIYYTIPtyHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSrLLSYDDRNDanfagHVISN 250
Cdd:COG0436 165 K-----AIVLNSP--NNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVS-ILSLPGLKD-----RTIVI 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 251 GSFSKILG-PGVRLGWLEVPPRL-KPILDGSGFATSGgcfnnyTSGIV--GSLFELKLAQKQISESYEAYKERMlattQV 326
Cdd:COG0436 232 NSFSKSYAmTGWRIGYAVGPPELiAALLKLQSNLTSC------APTPAqyAAAAALEGPQDYVEEMRAEYRRRR----DL 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 327 LRDELPDC-CKLVSPTGGYFIWVRIPD-RLDCREFLKYCMENHKIYFIVGTRFsadGQSGKQFFRLSIAfYPKSKLVDGA 404
Cdd:COG0436 302 LVEGLNEIgLSVVKPEGAFYLFADVPElGLDSEEFAERLLEEAGVAVVPGSAF---GPAGEGYVRISYA-TSEERLEEAL 377
|
410
....*....|
gi 21356535 405 RRLCNALKDY 414
Cdd:COG0436 378 ERLARFLERY 387
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
24-411 |
2.82e-30 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 119.72 E-value: 2.82e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 24 PNILNLGVGAPgpdiLTANCDSFRTAtdhclEREKRENQSLiFQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTG 103
Cdd:pfam00155 1 TDKINLGSNEY----LGDTLPAVAKA-----EKDALAGGTR-NLYGPTDGHPELREALAKFLGRSPVLKLDREAAVVFGS 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 104 ASHGLHILLSTMLDFEG-FVFVDEYTYMIALDSIKHfSTVTIVPVKL---NDDGVDLKDLEEKVSKRRFqskkkefwGIY 179
Cdd:pfam00155 71 GAGANIEALIFLLANPGdAILVPAPTYASYIRIARL-AGGEVVRYPLydsNDFHLDFDALEAALKEKPK--------VVL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 180 YTIPtyHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSRLLSYDDRndanfaGHVISNGSFSKILG- 258
Cdd:pfam00155 142 HTSP--HNPTGTVATLEELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRALLAEG------PNLLVVGSFSKAFGl 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 259 PGVRLGWLEVPPRLKPILDGsgfATSGGCFNNYTSGIVGSLFElklAQKQISESYEAYKERMLATTQVLRDELPDC-CKL 337
Cdd:pfam00155 214 AGWRVGYILGNAAVISQLRK---LARPFYSSTHLQAAAAAALS---DPLLVASELEEMRQRIKERRDYLRDGLQAAgLSV 287
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21356535 338 VSPTGGYFIWVRIpDRLDCREFLKYCMENHKIYFIVGTRFSADGqsgkqFFRLSIAFYPKSKLvdgaRRLCNAL 411
Cdd:pfam00155 288 LPSQAGFFLLTGL-DPETAKELAQVLLEEVGVYVTPGSSPGVPG-----WLRITVAGGTEEEL----EELLEAI 351
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
24-391 |
1.86e-24 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 104.03 E-value: 1.86e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 24 PNILNLGVGapGPDILTancdsfrtaTDHCLEREKRENQSLIFQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTG 103
Cdd:PRK06348 29 PDIIDLSLG--DPDLIT---------DESIINAAFEDAKKGHTRYTDSGGDVELIEEIIKYYSKNYDLSFKRNEIMATVG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 104 ASHGLHILLSTMLDFEGFVFVDEYTYMIALDSIKHFSTVTIVPVKLNDDG--VDLKDLEEKVSkrrfqSKKKEFwgiyyT 181
Cdd:PRK06348 98 ACHGMYLALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEEDGfqINVKKLEALIT-----SKTKAI-----I 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 182 IPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPThsRLLSYDDRNDanfagHVISNGSFSKILG-PG 260
Cdd:PRK06348 168 LNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFYEDFV--PMATLAGMPE-----RTITFGSFSKDFAmTG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 261 VRLGWLEVPPRlkpILDGSGFATSGGCFNNYTSGIVGSLFELKLAQKQISESYEAYKERMLATTQvlRDELPDCCKLVSP 340
Cdd:PRK06348 241 WRIGYVIAPDY---IIETAKIINEGICFSAPTISQRAAIYALKHRDTIVPLIKEEFQKRLEYAYK--RIESIPNLSLHPP 315
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 21356535 341 TGGYFIWVRIPDR-LDCREFLKYCMENHKIYFIVGTRFsadGQSGKQFFRLS 391
Cdd:PRK06348 316 KGSIYAFINIKKTgLSSVEFCEKLLKEAHVLVIPGKAF---GESGEGYIRLA 364
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
59-391 |
5.52e-22 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 96.80 E-value: 5.52e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 59 RENQSLIFQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGASHGLHILLSTMLD-------FEGFvFVdEYTYMI 131
Cdd:PRK06836 60 EEEDPGLHGYMPNAGYPEVREAIAESLNRRFGTPLTADHIVMTCGAAGALNVALKAILNpgdevivFAPY-FV-EYRFYV 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 132 AldsiKHFSTVTIVPVKLNDDGVDLKDLEEKVSKRrfqskkkefwgiyyT----IPTYHNPTGILFSPEVCRGIVQLAR- 206
Cdd:PRK06836 138 D----NHGGKLVVVPTDTDTFQPDLDALEAAITPK--------------TkaviINSPNNPTGVVYSEETLKALAALLEe 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 207 -----NYDFLVVCDDVYnilnygetpthsRLLSYDDRNDAN---FAGHVISNGSFSKILG-PGVRLGWLEVPPRL---KP 274
Cdd:PRK06836 200 kskeyGRPIYLISDEPY------------REIVYDGAEVPYifkYYDNSIVVYSFSKSLSlPGERIGYIAVNPEMedaDD 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 275 ILDGSGFATSGGCFNNYTSgivgslfelkLAQKQISES------YEAYKERMLATTQVLRDELPDCcklVSPTGGYFIWV 348
Cdd:PRK06836 268 LVAALVFANRILGFVNAPA----------LMQRVVAKCldatvdVSIYKRNRDLLYDGLTELGFEC---VKPQGAFYLFP 334
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 21356535 349 RIPDRlDCREFLKYCMEnHKIYFIVGTRFSADGqsgkqFFRLS 391
Cdd:PRK06836 335 KSPEE-DDVAFCEKAKK-HNLLLVPGSGFGCPG-----YFRLS 370
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
6-413 |
1.24e-21 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 95.71 E-value: 1.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 6 QDRKLKHLFDGGDwnvYAPNILNLGVGAPGPDiltancdsfrtATDHCLEREKRENQSLIFQYGPTSGTFEVRREISTYF 85
Cdd:PRK08361 18 QRSKIRELFERAS---KMENVISLGIGEPDFD-----------TPKNIKEAAKRALDEGWTHYTPNAGIPELREAIAEYY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 86 TEMFKSPVNCEDLIITTGASHGLHILLSTMLDFEGFVFVDEYTYMIALDSIKhFSTVTIVPVKL---NDDGVDLKDLEEK 162
Cdd:PRK08361 84 KKFYGVDVDVDNVIVTAGAYEATYLAFESLLEEGDEVIIPDPAFVCYVEDAK-IAEAKPIRIPLreeNEFQPDPDELLEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 163 VSKRRFQskkkefwgIYYTIPtyHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYgETPTHSRLLSYDDRNdan 242
Cdd:PRK08361 163 ITKRTRM--------IVINYP--NNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLY-EGAKHYPMIKYAPDN--- 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 243 faghVISNGSFSKILG-PGVRLGWLEVPPR-LKPILDgsgfatsggcFNNYTSGIVGSLFEL--------KLAQKQISES 312
Cdd:PRK08361 229 ----TILANSFSKTFAmTGWRLGFVIAPEQvIKDMIK----------LHAYIIGNVASFVQIagiealrsKESWKAVEEM 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 313 YEAYKERMLATTQVLRdELPDcCKLVSPTGGYFIWVRIPDR-LDCREFLKYCMENHKIYFIVGTRFsadGQSGKQFFRLS 391
Cdd:PRK08361 295 RKEYNERRKLVLKRLK-EMPH-IKVFEPKGAFYVFANIDETgMSSEDFAEWLLEKARVVVIPGTAF---GKAGEGYIRIS 369
|
410 420
....*....|....*....|..
gi 21356535 392 IAfYPKSKLVDGARRLCNALKD 413
Cdd:PRK08361 370 YA-TSKEKLIEAMERMEKALEE 390
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
68-414 |
2.12e-19 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 89.41 E-value: 2.12e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 68 YGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGASHGLHILLSTMLDfEGfvfvDE--------YTY--MIALdsik 137
Cdd:PRK05764 64 YTPAAGIPELREAIAAKLKRDNGLDYDPSQVIVTTGAKQALYNAFMALLD-PG----DEviipapywVSYpeMVKL---- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 138 hfSTVTIVPVKLN-DDG--VDLKDLEEKVSKRrfqSKkkefwGIYYTIPtyHNPTGILFSPEVCRGIVQLARNYDFLVVC 214
Cdd:PRK05764 135 --AGGVPVFVPTGeENGfkLTVEQLEAAITPK---TK-----ALILNSP--SNPTGAVYSPEELEAIADVAVEHDIWVLS 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 215 DDVYNILNYGETPTHSRLLSYDD-RNDAnfaghVISNGsFSKILG-PGVRLGWLEVPPRL-KPILDGSGFATSggCFNNy 291
Cdd:PRK05764 203 DEIYEKLVYDGAEFTSIASLSPElRDRT-----ITVNG-FSKAYAmTGWRLGYAAGPKELiKAMSKLQSHSTS--NPTS- 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 292 tsgIV--GSLFELKLAQKQISESYEAYKERMlattQVLRDELPDCCKL--VSPTGGYFIWVRIPD-----RLDCREFLKY 362
Cdd:PRK05764 274 ---IAqyAAVAALNGPQDEVEEMRQAFEERR----DLMVDGLNEIPGLecPKPEGAFYVFPNVSKllgksITDSLEFAEA 346
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 21356535 363 CMENHKIYFIVGTRFSADGqsgkqFFRLSIAfYPKSKLVDGARRLCNALKDY 414
Cdd:PRK05764 347 LLEEAGVAVVPGIAFGAPG-----YVRLSYA-TSLEDLEEGLERIERFLESL 392
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
68-404 |
2.58e-17 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 82.93 E-value: 2.58e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 68 YGPTSGTFEVRREIStyFTEMFKSPVNC--EDLIITTGASHGLHILLSTMLDFEGFVFVDEYTYMIALDSIKHFSTVTIV 145
Cdd:PRK08363 66 YGPSEGLPELREAIV--KREKRKNGVDItpDDVRVTAAVTEALQLIFGALLDPGDEILIPGPSYPPYTGLVKFYGGVPVE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 146 PVKLNDDG--VDLKDLEEKVSKRRfqskkkefwgIYYTIPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNY 223
Cdd:PRK08363 144 YRTIEEEGwqPDIDDIRKKITEKT----------KAIAVINPNNPTGALYEKKTLKEILDIAGEHDLPVISDEIYDLMTY 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 224 GETPTHSRLLSYDDrndanfagHVISNGSFSKI-LGPGVRLGWL---EVPPRLKPILDG-SGFATSGGCFNnyTSGIVGS 298
Cdd:PRK08363 214 EGKHVSPGSLTKDV--------PVIVMNGLSKVyFATGWRLGYIyfvDPEGKLAEVREAiDKLARIRLCPN--TPAQFAA 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 299 LFELKLAQKQISESYEAYKERMLATTQVLrDELPDcCKLVSPTGGYFIWVRI---PDRLDcREFLKYCMENHKIYFIVGT 375
Cdd:PRK08363 284 IAGLTGPMDYLEEYMKKLKERRDYIYKRL-NEIPG-ISTTKPQGAFYIFPRIeegPWKDD-KEFVLDVLHEAHVLFVHGS 360
|
330 340
....*....|....*....|....*....
gi 21356535 376 RFsadGQSGKQFFRlsIAFYPKSKLVDGA 404
Cdd:PRK08363 361 GF---GEYGAGHFR--LVFLPPVEILEEA 384
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
26-407 |
1.74e-14 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 74.68 E-value: 1.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 26 ILNLGVGAPGPDILTANCDSFRTATDHCLEREKRENqslifqYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGAS 105
Cdd:TIGR01265 33 VIPLSHGDPSVFGNLRTDPEAEEAVKDALRSGKFNG------YAPSVGALAAREAVAEYLSSDLPGKLTADDVVLTSGCS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 106 HGLHILLSTMLDFEGFVFVDEYTYMIaLDSIKHFSTVTIVPVKL---NDDGVDLKDLEekvskrrfQSKKKEFWGIYYTI 182
Cdd:TIGR01265 107 QAIEICIEALANPGANILVPRPGFPL-YDTRAAFSGLEVRLYDLlpeKDWEIDLDGLE--------SLADEKTVAIVVIN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 183 PTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSRllsyddrndANFAGHV--ISNGSFSK-ILGP 259
Cdd:TIGR01265 178 PS--NPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPM---------ASFASIVpvLSLGGISKrWVVP 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 260 GVRLGWLEVPPR----LKPILDGsgfatsggcFNNYTSGIVGSLFELKLAQKQI----SESYEAYKERMLATT-QVLRDE 330
Cdd:TIGR01265 247 GWRLGWIIIHDPhgifRDTVLQG---------LKNLLQRILGPATIVQGALPDIlentPQEFFDGKISVLKSNaELCYEE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 331 LPDCCKL--VSPTGGYFIWVRI-----PDRLDCREFLKYCMENHKIYFIVGTRFSADGqsgkqFFRLSIAFyPKSKLVDG 403
Cdd:TIGR01265 318 LKDIPGLvcPKPEGAMYLMVKLelelfPEIKDDVDFCEKLAREESVICLPGSAFGLPN-----WVRITITV-PESMLEEA 391
|
....
gi 21356535 404 ARRL 407
Cdd:TIGR01265 392 CSRI 395
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
10-365 |
3.43e-13 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 70.81 E-value: 3.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 10 LKHLFDGGDwnvYAPNIlNLGVGAPgpdiltANCDSFRT---ATDHCLE--REKRENQslifqYGPTSGTFEVRREISTY 84
Cdd:PLN00143 22 LKENFNEDD---HRLAI-SFGFGDP------SCFECFRTtniAEDAIVEavRSAKFNS-----YAPTGGILPARRAIADY 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 85 FTEMFKSPVNCEDLIITTGASHGLHILL--------STMLDFEGFVFVDEYTYMIALDsIKHFStvtIVPVKLNDdgVDL 156
Cdd:PLN00143 87 LSNDLPYQLSPDDVYLTLGCKHAAEIIIkvlarpeaNILLPRPGFPDVETYAIFHHLE-IRHFD---LLPEKGWE--VDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 157 kDLEEKVSKRRfqskkkefwGIYYTIPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSRLLsyd 236
Cdd:PLN00143 161 -DAVEAIADEN---------TIAMVIINPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFGSKPFVPMGL--- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 237 drndanFAG--HVISNGSFSK-ILGPGVRLGWLEVPprlkpilDGSGFATSGGCFNNYTSGIVGSLFELKLAQKQISESY 313
Cdd:PLN00143 228 ------FASivPVITLGSISKrWMIPGWGLGWLVTC-------DPSGLLQICEIADSIKKALNPAPFPPTFIQAAIPEIL 294
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21356535 314 EAYKERMLATT-QVLRDELPDC--------CKLV--SPTGGYFIWVRIPDRL--DCREFLKYCME 365
Cdd:PLN00143 295 EKTTEDFFSKTiNILRAALAFCydklkeipCIMCpqKAEGAFFALVKLNLLLleDIEDDMEFCLK 359
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
24-418 |
8.35e-13 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 69.37 E-value: 8.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 24 PNILNLGVGAPgpdiltancdSFRTAtDHCLEREKR---ENQSlifQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLII 100
Cdd:PRK07309 30 PGILKLTLGEP----------DFTTP-DHVKEAAKRaidANQS---HYTGMAGLLELRQAAADFVKEKYNLDYAPENEIL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 101 TT-GASHGLHILLSTMLDFEGFVFVDEYTYMiALDSIKHFSTVTIVPVKLNDDGVDL--KDLEEKVSKRRFQSKkkefwG 177
Cdd:PRK07309 96 VTiGATEALSASLTAILEPGDKVLLPAPAYP-GYEPIVNLVGAEIVEIDTTENDFVLtpEMLEKAILEQGDKLK-----A 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 178 IYYTIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPtHSRLLSYddRNDANFaghVISNGSFSKIL 257
Cdd:PRK07309 170 VILNYPA--NPTGVTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEP-HVSIAEY--LPDQTI---LINGLSKSHAM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 258 gPGVRLGWLEVPPRLkpildgsgfatsggcfnnyTSGIVGSLFELKLAQKQISE--SYEAYK------ERMLATTQVLRD 329
Cdd:PRK07309 242 -TGWRIGLIFAPAEF-------------------TAQLIKSHQYLVTAATTMAQfaAVEALTngkddaLPMKKEYIKRRD 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 330 ----ELPDC-CKLVSPTGGYFIWVRIPDRL--DCREFLKYCMENHKIYFIVGTRFsadGQSGKQFFRLSiafYPKS--KL 400
Cdd:PRK07309 302 yiieKMTDLgFKIIKPDGAFYIFAKIPAGYnqDSFKFLQDFARKKAVAFIPGAAF---GPYGEGYVRLS---YAASmeTI 375
|
410
....*....|....*...
gi 21356535 401 VDGARRlcnaLKDYIAEQ 418
Cdd:PRK07309 376 KEAMKR----LKEYMEEH 389
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
68-412 |
9.58e-13 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 69.20 E-value: 9.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 68 YGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGASHGLHILLSTMLDfEGfvfvDEytyMIAL--------DSIK-H 138
Cdd:PRK06108 57 YTHNLGIPELREALARYVSRLHGVATPPERIAVTSSGVQALMLAAQALVG-PG----DE---VVAVtplwpnlvAAPKiL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 139 FSTVTIVPVKLNDDG--VDLKDLEEKVSKR-RfqskkkefwGIYYTIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCD 215
Cdd:PRK06108 129 GARVVCVPLDFGGGGwtLDLDRLLAAITPRtR---------ALFINSPN--NPTGWTASRDDLRAILAHCRRHGLWIVAD 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 216 DVYNILNYGETPTHSRLLSYDDRNDanfagHVISNGSFSK-ILGPGVRLGWLEVPPRLKPILDGsgfatsggcFNNY-TS 293
Cdd:PRK06108 198 EVYERLYYAPGGRAPSFLDIAEPDD-----RIIFVNSFSKnWAMTGWRLGWLVAPPALGQVLEK---------LIEYnTS 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 294 GIvgSLFELKLAQKQISESyEAYKERMLATTQVLRDELPDCCK------LVSPTGGYFIWVRIPDRLDCREFLKYCMENH 367
Cdd:PRK06108 264 CV--AQFVQRAAVAALDEG-EDFVAELVARLRRSRDHLVDALRalpgveVAKPDGAMYAFFRIPGVTDSLALAKRLVDEA 340
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 21356535 368 KIYFIVGTRFSADGQSgkqFFRLSIAFYPkSKLVDGARRLCNALK 412
Cdd:PRK06108 341 GLGLAPGTAFGPGGEG---FLRWCFARDP-ARLDEAVERLRRFLA 381
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
25-272 |
2.46e-12 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 67.84 E-value: 2.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 25 NILNLGVGAPgpDILTANcdSFRTATDHCLEREkrenqslIFQYGPTSGTFEVRREISTYFTEMFKSPVNCED-LIITTG 103
Cdd:PRK07682 21 GVISLGVGEP--DFVTPW--NVREASIRSLEQG-------YTSYTANAGLLELRQEIAKYLKKRFAVSYDPNDeIIVTVG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 104 ASHGLHILLSTMLDFEGFVFVDEYTYmIALDSIKHFSTVTIVPVKLN-DDG--VDLKDLEEKVSKRrfqSKkkefwGIYY 180
Cdd:PRK07682 90 ASQALDVAMRAIINPGDEVLIVEPSF-VSYAPLVTLAGGVPVPVATTlENEfkVQPAQIEAAITAK---TK-----AILL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 181 TIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGEtpTHSRLLSYDDRNDanfagHVISNGSFSKILG-P 259
Cdd:PRK07682 161 CSPN--NPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDE--AYTSFASIKGMRE-----RTILISGFSKGFAmT 231
|
250
....*....|...
gi 21356535 260 GVRLGWLEVPPRL 272
Cdd:PRK07682 232 GWRLGFIAAPVYF 244
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
73-378 |
6.76e-12 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 66.71 E-value: 6.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 73 GTFEVRREISTYFTEMFKSPVNCED-LIITTGASHGLHILLSTMLDFEGFVFVDEYTYMiALDSIKHFSTVTIVPVKLN- 150
Cdd:PRK06207 79 GDADIRELLAARLAAFTGAPVDAADeLIITPGTQGALFLAVAATVARGDKVAIVQPDYF-ANRKLVEFFEGEMVPVQLDy 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 151 ---DD--GVDLKDLEEKvskrrFQSKKKEFwgiYYTIPtyHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNY-G 224
Cdd:PRK06207 158 lsaDKraGLDLDQLEEA-----FKAGVRVF---LFSNP--NNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYdG 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 225 ETPTHSRLLSYDDRNdanfaghVISngsfskILGP-------GVRLGWLEVPP-------RLKPI--LDGSGfatsggcf 288
Cdd:PRK06207 228 TSYTHLRALPIDPEN-------VIT------IMGPskteslsGYRLGVAFGSPaiidrmeKLQAIvsLRAAG-------- 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 289 nnYTSGIVGSLFelklaqkqiSESYEAYKERmLATTQVLRDEL------PDCCKLVSPTGGYFIWVRIPdRLDCR--EFL 360
Cdd:PRK06207 287 --YSQAVLRTWF---------SEPDGWMKDR-IARHQAIRDDLlrvlrgVEGVFVRAPQAGSYLFPRLP-RLAVSlhDFV 353
|
330
....*....|....*...
gi 21356535 361 KYCMENHKIYFIVGTRFS 378
Cdd:PRK06207 354 KILRLQAGVIVTPGTEFS 371
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
26-277 |
6.68e-11 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 63.54 E-value: 6.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 26 ILNLGVGAPgpdiltancdSFrTATDHCLEREKRENQSLIFQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGAS 105
Cdd:PRK07337 32 IIHMGIGEP----------DF-TAPEPVVEAAARALRRGVTQYTSALGLAPLREAIAAWYARRFGLDVAPERIVVTAGAS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 106 HGLHILLSTMLDFEGFVFVDEYTYmialDSIKHF-STVTIVPVklnddgvdlkdLEEKVSKRRFQ---SKKKEFW----- 176
Cdd:PRK07337 101 AALLLACLALVERGDEVLMPDPSY----PCNRHFvAAAEGRPV-----------LVPSGPAERFQltaADVEAAWgertr 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 177 GIYYTIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPtHSRLLSYDDrndanfaghVISNGSFSKI 256
Cdd:PRK07337 166 GVLLASPS--NPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYDAAP-VSALSLGDD---------VITINSFSKY 233
|
250 260
....*....|....*....|..
gi 21356535 257 LG-PGVRLGWLEVPPRLKPILD 277
Cdd:PRK07337 234 FNmTGWRLGWLVVPEALVGTFE 255
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
27-255 |
1.12e-10 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 62.95 E-value: 1.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 27 LNLGvgapGPDILTAncDSFRTATdhclerekRENQSLIFQYGPTSGTFEVRREISTYFtEMFKSPVNCEDLIITTGASH 106
Cdd:PRK07568 35 LNIG----QPDIKTP--EVFFEAI--------KNYDEEVLAYSHSQGIPELREAFAKYY-KKWGIDVEPDEILITNGGSE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 107 GLHILLSTMLDFEGFVFVDE--YT-YMIALDSikhfSTVTIVPVKLN-DDGVDL---KDLEEKVSKRrfqSKkkefwGIY 179
Cdd:PRK07568 100 AILFAMMAICDPGDEILVPEpfYAnYNGFATS----AGVKIVPVTTKiEEGFHLpskEEIEKLITPK---TK-----AIL 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21356535 180 YTIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSrLLSYDDRNDanfagHVISNGSFSK 255
Cdd:PRK07568 168 ISNPG--NPTGVVYTKEELEMLAEIAKKHDLFLISDEVYREFVYDGLKYTS-ALSLEGLED-----RVIIIDSVSK 235
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
67-346 |
1.75e-10 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 62.36 E-value: 1.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 67 QYGPTSGTFEVRREISTYFTEMFKSPVNCE-DLIITTGASHGLHILLSTMLD-------FEGFVfvDEYTYMIALdsikh 138
Cdd:PRK07777 56 QYPPGPGIPELRAAIAAQRRRRYGLEYDPDtEVLVTVGATEAIAAAVLGLVEpgdevllIEPYY--DSYAAVIAM----- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 139 fSTVTIVPVKLNDDG----VDLKDLEEKVSKRrfqskkkefwgiyyT----IPTYHNPTGILFSPEVCRGIVQLARNYDF 210
Cdd:PRK07777 129 -AGAHRVPVPLVPDGrgfaLDLDALRAAVTPR--------------TraliVNSPHNPTGTVLTAAELAAIAELAVEHDL 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 211 LVVCDDVYNILNYgETPTHSRLLSYDdrndaNFAGHVISNGSFSKILG-PGVRLGWLEVPPrlkPILDGSGFAtsggcfN 289
Cdd:PRK07777 194 LVITDEVYEHLVF-DGARHLPLATLP-----GMRERTVTISSAAKTFNvTGWKIGWACGPA---PLIAAVRAA------K 258
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 21356535 290 NYTSGIVGSLFELKLAQKQISEsyEAYKERMLATTQVLRDELPDCC-----KLVSPTGGYFI 346
Cdd:PRK07777 259 QYLTYVGGAPFQPAVAHALDHE--DAWVAALRDSLQAKRDRLAAGLaeagfEVHDSAGTYFL 318
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
155-268 |
5.34e-10 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 60.73 E-value: 5.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 155 DLKDLEEKVSKRRFQSkkkefwGIYYTIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSrlLS 234
Cdd:PRK06855 158 DLDDLENKVKYNPSIA------GILLINPD--NPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVYNGKKTVP--LS 227
|
90 100 110
....*....|....*....|....*....|....*..
gi 21356535 235 yddrndaNFAGHV--ISNGSFSKILG-PGVRLGWLEV 268
Cdd:PRK06855 228 -------EVIGDVpgIALKGISKELPwPGSRCGWIEV 257
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
187-412 |
6.46e-10 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 60.47 E-value: 6.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 187 NPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPtHSRLLSYDDRndanfAGHVISNGSFSKILG-PGVRLGW 265
Cdd:PRK05957 171 NPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGVK-HFSPGSIPGS-----GNHTISLYSLSKAYGfASWRIGY 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 266 LEVPPRL----KPILDgsgfaTSGGC---FNNYTSgiVGSLfelklaqkQISESY-EAYKERMLATTQVLRD---ELPDC 334
Cdd:PRK05957 245 MVIPIHLleaiKKIQD-----TILICppvVSQYAA--LGAL--------QVGKSYcQQHLPEIAQVRQILLKslgQLQDR 309
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21356535 335 CKLVSPTGGYFIWVRIPDRLDCREFLKYCMENHKIYFIVGTRFsadGQSGKQFFRLSIAFYPKSKLVDGARRLCNALK 412
Cdd:PRK05957 310 CTLHPANGAFYCFLKVNTDLNDFELVKQLIREYRVAVIPGTTF---GMKNGCYLRIAYGALQKATAKEGIERLVQGLK 384
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
68-407 |
6.15e-09 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 57.49 E-value: 6.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 68 YGPTSGTFEVRREISTYFTEMfKSPVNCEDLIITTGASHGLHILLSTMLDFEGFVFVDEYTYmialdsiKHFSTVTI--- 144
Cdd:TIGR01264 69 YAPTVGALSAREAIASYYHNP-DGPIEADDVVLCSGCSHAIEMCIAALANAGQNILVPRPGF-------PLYETLAEsmg 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 145 VPVKL------NDDGVDLKDLEekvskrrfQSKKKEFWGIYYTIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVY 218
Cdd:TIGR01264 141 IEVKLynllpdKSWEIDLKQLE--------SLIDEKTAALIVNNPS--NPCGSVFSRQHLEEILAVAERQCLPIIADEIY 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 219 NILNYGETpTHSRLLSYDDRNDanfaghVISNGSFSK-ILGPGVRLGWLEVPPR---LKPILDGsgfatsggcFNNYTSG 294
Cdd:TIGR01264 211 GDMVFSGA-TFEPLASLSSTVP------ILSCGGLAKrWLVPGWRLGWIIIHDRrgiLRDIRDG---------LVKLSQR 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 295 IVGSLFELKLAQKQI----SESYEAYKERMLATTQVLRDE-LPDCCKL--VSPTGGYFIWVRI-----PDRLDCREFLKY 362
Cdd:TIGR01264 275 ILGPCTIVQGALPSIllrtPQEYFDGTLSVLESNAMLCYGaLAAVPGLrpVMPSGAMYMMVGIemehfPEFKNDVEFTER 354
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 21356535 363 CMENHKIYFIVGTRFSADGqsgkqFFRLSIAfYPKSKLVDGARRL 407
Cdd:TIGR01264 355 LVAEQSVFCLPGSCFEYPG-----FFRVVLT-VPVVMMEEACSRI 393
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
68-266 |
1.42e-06 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 50.15 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 68 YGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGASHGLHILLST--------MLDFEGFVFVDEYTYMIALDsIKHF 139
Cdd:PLN00145 90 YSTCVGLLPARRAIAEYLSRDLPYELSTDDIYLTAGCAQAIEIIMSVlaqpganiLLPRPGYPLYEARAVFSGLE-VRHF 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 140 StvtIVPVKlnDDGVDLKDLEEKVSKRRfqskkkefwgIYYTIPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYN 219
Cdd:PLN00145 169 D---LLPER--GWEVDLEGVEALADENT----------VAMVIINPNNPCGSVYSYEHLAKIAETARKLGILVIADEVYD 233
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 21356535 220 ILNYGETPthsrllsyddrndanFA-----GH---VISNGSFSK-ILGPGVRLGWL 266
Cdd:PLN00145 234 HLTFGSKP---------------FVpmgvfGEvapVLTLGSISKrWVVPGWRLGWI 274
|
|
| Asp_aminotransf |
pfam12897 |
Aspartate amino-transferase; These proteins catalyze the reversible transfer of an amino group ... |
137-346 |
1.63e-06 |
|
Aspartate amino-transferase; These proteins catalyze the reversible transfer of an amino group from the amino acid substrate to an acceptor alpha-keto acid. They require pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze this reaction. Trans-amination reactions are of central importance in amino acid metabolism and in links to carbohydrate and fat metabolism. This class of amino-transferases acts as dimers in a head-to-tail configuration. It has been demonstrated that these proteins are aspartate amino-transferases from Bacteria (Jansen, R.S. et al. Nat Commun 11, 1960 (2020)).
Pssm-ID: 403948 Cd Length: 419 Bit Score: 49.86 E-value: 1.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 137 KHFST-----VTIVPVKLNDDGVDLKDLEEKVSKrrfQSKKKEFWgiyyTIPTYHNPTGILFSPEVCRGIVQL-ARNYDF 210
Cdd:pfam12897 135 RHFAIletlgIEMITVDLQDDGPDMDAVERLVAK---DPSIKGIW----FVPKYSNPTGETISEEVARRLAGMkTAAPDF 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 211 LVVCDDVYNILN-YGETPthsrllsyddrNDANF------AGH---VISNGSFSKILGPGVRLGWlevpprlkpildgsg 280
Cdd:pfam12897 208 RIFWDNAYAVHHlVGEGD-----------RDPNIvglardAGHpnrPFVFASTSKITFAGAGVGF--------------- 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 281 FATSG---GCFNNYTSgiVGSLFELKLAQKQISESYEAYK--------------ERMLATTQVLRDEL--PDCCKLVSPT 341
Cdd:pfam12897 262 VASSEdniAWLGKYLG--AQSIGPDKVNQLRHVRFLGDYEgleghmrrhaaliaPKFAAVLEILEAELggGGYATWTEPR 339
|
....*
gi 21356535 342 GGYFI 346
Cdd:pfam12897 340 GGYFI 344
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
25-266 |
1.88e-06 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 49.74 E-value: 1.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 25 NILNLGVGAPGPdiltancdsFRTATDHCLEREKRENQSLIFQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGA 104
Cdd:PRK13355 147 HILKLNIGNPAP---------FGFRTPDEVVYDMAQQLTDTEGYSDSKGLFSARKAIMQYAQLKGLPNVDVDDIYTGNGV 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 105 SHGLHILLSTMLDFEGFVFVD--EYTYMIALDSIKHFSTVTIVPVKLNDDGVDLKDLEEKVSkrrfqSKKKefwGIYYTI 182
Cdd:PRK13355 218 SELINLSMSALLDDGDEVLIPspDYPLWTACVNLAGGTAVHYRCDEQSEWYPDIDDIRSKIT-----SRTK---AIVIIN 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 183 PtyHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYgETPTHSRLLSY-DDRNDANFAG----HVISngsfskil 257
Cdd:PRK13355 290 P--NNPTGALYPREVLQQIVDIAREHQLIIFSDEIYDRLVM-DGLEHTSIASLaPDLFCVTFSGlsksHMIA-------- 358
|
....*....
gi 21356535 258 gpGVRLGWL 266
Cdd:PRK13355 359 --GYRIGWM 365
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
186-414 |
2.11e-06 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 49.55 E-value: 2.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 186 HNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNY-GETPTHSRLlsYDdrndanfAGhvISNGSFSKILG-PGVRL 263
Cdd:PRK07324 163 NNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRPLDEdGSTPSIADL--YE-------KG--ISTNSMSKTYSlPGIRV 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 264 GWL----EVPPRLKPILDgsgFAT-SGGCFNNYTSGIVgslfeLKLAQKqISESYEAYKERMLATTQ--VLRDELPDCCK 336
Cdd:PRK07324 232 GWIaaneEVIDILRKYRD---YTMiCAGVFDDMLASLA-----LEHRDA-ILERNRKIVRTNLAILDewVAKEPRVSYVK 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 337 lvsPTGG--YFIWVRIPdrLDCREFLKYCMENHKIYFIVGTRFSADGqsgkqFFRLSIAFYPKSkLVDGARRLCNALKDY 414
Cdd:PRK07324 303 ---PKAVstSFVKLDVD--MPSEDFCLKLLKETGVLLVPGNRFDLEG-----HVRIGYCCDTET-LKKGLKKLSEFLREF 371
|
|
| PLN02368 |
PLN02368 |
alanine transaminase |
68-218 |
2.17e-06 |
|
alanine transaminase
Pssm-ID: 177996 [Multi-domain] Cd Length: 407 Bit Score: 49.41 E-value: 2.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 68 YGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGASHGLHILLSTMLDFEG---FVFVDEYTYMIAldSIKHFSTvTI 144
Cdd:PLN02368 103 YSDSRGLPGVRKEVAEFIERRDGYPSDPELIFLTDGASKGVMQILNAVIRGEKdgvLVPVPQYPLYSA--TISLLGG-TL 179
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21356535 145 VPVKLNDD---GVDLKDLEEKVSKRRfqSKKKEFWGIYYTIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVY 218
Cdd:PLN02368 180 VPYYLEESenwGLDVNNLRQSVAQAR--SKGITVRAMVIINPG--NPTGQCLSEANLREILKFCYQERLVLLGDEVY 252
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
70-414 |
2.83e-06 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 48.97 E-value: 2.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 70 PTSGTFEVRREISTYFTemfkspVNCEDLIITTGASHGLHILLSTMLDFEGFVFVDEYTYM---IALDSIKHfstvTIVP 146
Cdd:COG0079 46 PDPDATALREALAEYYG------VPPEQVLVGNGSDELIQLLARAFLGPGDEVLVPEPTFSeypIAARAAGA----EVVE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 147 VKLNDD-GVDLKDLEEKVSKR-RfqskkkefwGIYytIPTYHNPTGILFSPEVcrgIVQLARNYDF--LVVCDDVyniln 222
Cdd:COG0079 116 VPLDEDfSLDLDALLAAITERtD---------LVF--LCNPNNPTGTLLPREE---LEALLEALPAdgLVVVDEA----- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 223 YGE-TPTHSRLLSYDDRNDanfagHVISNGSFSKILG-PGVRLGWLEVPPRLKPILDgsgfaTSGGCFNnytsgiVGSlf 300
Cdd:COG0079 177 YAEfVPEEDSALPLLARYP-----NLVVLRTFSKAYGlAGLRLGYAIASPELIAALR-----RVRGPWN------VNS-- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 301 elkLAQK--QISESYEAYKERMLATTQVLRDELPD-CCKL---VSPTGGYFIWVRIPDrlDCREFLKYCMEnHKIyfIVG 374
Cdd:COG0079 239 ---LAQAaaLAALEDRAYLEETRARLRAERERLAAaLRALgltVYPSQANFVLVRVPE--DAAELFEALLE-RGI--LVR 310
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 21356535 375 tRFSADGQSGkqFFRLSIafypksKLVDGARRLCNALKDY 414
Cdd:COG0079 311 -DFSSFGLPD--YLRITV------GTPEENDRLLAALKEI 341
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
183-352 |
8.27e-06 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 47.54 E-value: 8.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 183 PTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVY-----NIlNYGE-TPthsrllsyddrndaNFAGHVISNGSFSKI 256
Cdd:PRK09440 188 PT--NPTGNVLTDEELEKLDALARQHNIPLLIDNAYgppfpGI-IFSEaTP--------------LWNPNIILCMSLSKL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 257 LGPGVRLGWLEVPPRLKPILdgSGFATSGGCF-NNYTSGIVGSLFE----LKLAQKQISESYEAykeRMLATTQVLRDEL 331
Cdd:PRK09440 251 GLPGVRCGIVIADEEIIEAL--SNMNGIISLApGRLGPAIAAEMIEsgdlLRLSETVIRPFYRQ---KVQLAIALLRRYL 325
|
170 180
....*....|....*....|..
gi 21356535 332 PDC-CKLVSPTGGYFIWVRIPD 352
Cdd:PRK09440 326 PDEpCLIHKPEGAIFLWLWFKD 347
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
187-277 |
8.81e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 47.36 E-value: 8.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 187 NPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYG-ETPThsrLLSYDDrnDAnfagHVISngSFSKILG-PGVRLG 264
Cdd:PRK08960 176 NPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYGvDAAS---VLEVDD--DA----FVLN--SFSKYFGmTGWRLG 244
|
90
....*....|...
gi 21356535 265 WLEVPPRLKPILD 277
Cdd:PRK08960 245 WLVAPPAAVPELE 257
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
187-369 |
9.47e-06 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 47.34 E-value: 9.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 187 NPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPThsRLLSYDDRNDANFAGHvisngSFSKILG-PGVRLGW 265
Cdd:PRK06290 190 NPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDGKPL--SFLSVPGAKEVGVEIH-----SLSKAYNmTGWRLAF 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 266 LEVPPRLKpildgSGFATSGgcfNNYTSGivgslfELKLAQK---------QISESY-EAYKERMLATTQVLRDELPDCC 335
Cdd:PRK06290 263 VVGNELIV-----KAFATVK---DNNDSG------QFIAIQKagiyaldhpEITEKIrEKYSRRLDKLVKILNEVGFKAE 328
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 21356535 336 KlvsPTGGYFIWVRIPDRLDC-------REFLKYCMENHKI 369
Cdd:PRK06290 329 M---PGGTFYLYVKAPKGTKSgikfenaEEFSQYLIKEKLI 366
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
25-412 |
4.86e-05 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 45.24 E-value: 4.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 25 NILNLGVGAP---GPDILtancdsfRTATDHCLEREKRenqslifQYGPTSGTFEVRREISTYFTEMFKSPVNCE-DLII 100
Cdd:PLN00175 55 GAINLGQGFPnfdGPDFV-------KEAAIQAIRDGKN-------QYARGFGVPELNSAIAERFKKDTGLVVDPEkEVTV 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 101 TTGASHGLHillSTMLdfeGFV-----------FVDEYTYMIALDSIKhFSTVTIVPvklNDDGVDLKDLEEKVSKrrfq 169
Cdd:PLN00175 121 TSGCTEAIA---ATIL---GLInpgdevilfapFYDSYEATLSMAGAK-IKTVTLRP---PDFAVPEDELKAAFTS---- 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 170 sKKKEFwgiyyTIPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNY-GEtptHSRLLSYDDRNDanfagHVI 248
Cdd:PLN00175 187 -KTRAI-----LINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFeGD---HISMASLPGMYE-----RTV 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 249 SNGSFSKILG-PGVRLGWLEVPPRLKPildGSGFATSGGCFNNYTSGIVGSLFELKlaqkqISESY-EAYKERMLATTQV 326
Cdd:PLN00175 253 TMNSLGKTFSlTGWKIGWAIAPPHLTW---GVRQAHSFLTFATATPMQWAAVAALR-----APESYyEELKRDYSAKKDI 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 327 LRDELPDC-CKLVSPTGGYFIWV-RIPDRLDCR-EFLKYCMENHKIYFIVGTRFSADGQSGKQFFRLsiAFYPKSKLVDG 403
Cdd:PLN00175 325 LVEGLKEVgFKVYPSSGTYFVMVdHTPFGFENDiAFCEYLIEEVGVAAIPPSVFYLNPEDGKNLVRF--AFCKDEETLRA 402
|
410
....*....|
gi 21356535 404 A-RRLCNALK 412
Cdd:PLN00175 403 AvERMKTKLK 412
|
|
| PRK15481 |
PRK15481 |
transcriptional regulatory protein PtsJ; Provisional |
97-330 |
5.75e-05 |
|
transcriptional regulatory protein PtsJ; Provisional
Pssm-ID: 185378 [Multi-domain] Cd Length: 431 Bit Score: 45.04 E-value: 5.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 97 DLIITTGASHGLHILLSTMLDFEGFVFVDEYTYMIALDSIKHfSTVTIVPVKLNDDGVDLKDLEEKVSKrrfqskkkefw 176
Cdd:PRK15481 143 EIDLTSGAIDAIERLLCAHLLPGDSVAVEDPCFLSSINMLRY-AGFSASPVSVDAEGMQPEKLERALAQ----------- 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 177 GIYYTI--PTYHNPTGILFSPEVCRGIVQ-LARNYDFLVVCDDVYNILNygETPTHSRLlsydDRNDANFAghVISngSF 253
Cdd:PRK15481 211 GARAVIltPRAHNPTGCSLSARRAAALRNlLARYPQVLVIIDDHFALLS--SSPYHSVI----PQTTQRWA--LIR--SV 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 254 SKILGPGVRLGWL----EVPPRLKPILDgsgfatSGGcfnNYTSGIVGSLFELKLA----QKQISESYEAYKERMLATTQ 325
Cdd:PRK15481 281 SKALGPDLRLAFVasdsATSARLRLRLN------SGT---QWVSHLLQDLVYACLTdpeyQARLAQARLFYAQRRQKLAR 351
|
....*
gi 21356535 326 VLRDE 330
Cdd:PRK15481 352 ALQQY 356
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
67-408 |
6.53e-05 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 44.78 E-value: 6.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 67 QYGPTSGTFEVRREISTYFTEMFKSPVNC-EDLIITTGASHGLHILLSTMLDfEGfvfvDEYTYM-IALDS---IKHFST 141
Cdd:PRK12414 61 QYAPMAGIAALREALAEKTERLYGARYDPaSEVTVIASASEGLYAAISALVH-PG----DEVIYFePSFDSyapIVRLQG 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 142 VTIVPVKLNDDG--VDLKDLEEKVSKR-RFqskkkefwgiyYTIPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVY 218
Cdd:PRK12414 136 ATPVAIKLSPEDfrVNWDEVAAAITPRtRM-----------IIVNTPHNPSATVFSAADLARLAQLTRNTDIVILSDEVY 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 219 NILNYGETPTHSRllsyddRNDANFAGHVISNGSFSKILG-PGVRLGWLEVPPRL-KPILDGSGFATsggcFNNYTSGIV 296
Cdd:PRK12414 205 EHVVFDGARHHSM------ARHRELAERSVIVSSFGKSYHvTGWRVGYCLAPAELmDEIRKVHQFMV----FSADTPMQH 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 297 GslFELKLAQKQISESYEAYKERmlaTTQVLRDELPDC-CKLVSPTGGYFIWVRIPDRLDCR--EFLKYCMENHKIYFIV 373
Cdd:PRK12414 275 A--FAEALAEPASYLGLGAFYQR---KRDLLARELAGSrFELLPSEGSFFMLARFRHFSDESdsDFVLRLIRDARVATIP 349
|
330 340 350
....*....|....*....|....*....|....*
gi 21356535 374 GTRFSADGQSGKqFFRLSIAfYPKSKLVDGARRLC 408
Cdd:PRK12414 350 LSAFYTDGTDTG-LIRLSFS-KDDATLVEGARRLC 382
|
|
| PLN02231 |
PLN02231 |
alanine transaminase |
92-317 |
1.19e-04 |
|
alanine transaminase
Pssm-ID: 177876 [Multi-domain] Cd Length: 534 Bit Score: 44.16 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 92 PVNCEDLIITTGASHGLHILLSTMLDFE--GFVF----VDEYTYMIALDSikhfstVTIVPVKLNDD---GVDLKDLEEK 162
Cdd:PLN02231 188 PADPNDIFLTDGASPAVHMMMQLLIRSEkdGILCpipqYPLYSASIALHG------GTLVPYYLDEAtgwGLEISELKKQ 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 163 VSKRRfqSKKKEFWGIYYTIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNY-GETPTHS-----RLLSYD 236
Cdd:PLN02231 262 LEDAR--SKGITVRALVVINPG--NPTGQVLAEENQRDIVEFCKQEGLVLLADEVYQENVYvPDKKFHSfkkvaRSMGYG 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 237 DRNDANFAGHVISNGSFSKIlgpGVRLGWLEVPPRLKPILDGSGFATSGGCFNNYTSGIVGSLfeLKLAQKQISESYEAY 316
Cdd:PLN02231 338 EKDISLVSFQSVSKGYYGEC---GKRGGYMEVTGFTSDVREQIYKVASVNLCSNISGQILASL--VMSPPKPGDESYESY 412
|
.
gi 21356535 317 K 317
Cdd:PLN02231 413 M 413
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
67-411 |
2.30e-04 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 43.26 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 67 QYGPT-SGTFEVRREISTYFTEMFKSPVNCE-DLIITTGASHGLHILLSTMLDFEGFVFVDEYTYMIALDSIkHFSTVTI 144
Cdd:PRK07681 63 SYGYTlSGIQEFHEAVTEYYNNTHNVILNADkEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGI-QMAGATS 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 145 VPVKLNDDG---VDLKDLEEKVSKRrfqSKKkefwgIYYTIPTyhNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNIL 221
Cdd:PRK07681 142 YYMPLKKENdflPDLELIPEEIADK---AKM-----MILNFPG--NPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEF 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 222 NY-GETPThsRLLSYDDRNDANfaghvISNGSFSKILG-PGVRLGWLEVPPRL----------------KPILDGSGFA- 282
Cdd:PRK07681 212 YFdGNKPI--SFLSVPGAKEVG-----VEINSLSKSYSlAGSRIGYMIGNEEIvraltqfksntdygvfLPIQKAACAAl 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 283 TSGGCFnnytsgivgslfelklaqkqISESYEAYKERmlattqvlRDELPDCCKLV-----SPTGGYFIWVRIPDRLDCR 357
Cdd:PRK07681 285 RNGAAF--------------------CEKNRGIYQER--------RDTLVDGFRTFgwnvdKPAGSMFVWAEIPKGWTSL 336
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 21356535 358 EFLKYCMENHKIYFIVGTRFsadGQSGKQFFRLSIAfYPKSKLVDGARRLCNAL 411
Cdd:PRK07681 337 SFAYALMDRANVVVTPGHAF---GPHGEGFVRIALV-QDEEVLQQAVENIRNSG 386
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
155-218 |
3.57e-04 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 42.49 E-value: 3.57e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21356535 155 DLKDLEEKVSKRrfqSKkkefwGIYYTIPtyHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVY 218
Cdd:PRK09265 157 DLDDIRSKITPR---TK-----AIVIINP--NNPTGAVYSKELLEEIVEIARQHNLIIFADEIY 210
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
187-264 |
1.27e-03 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 40.71 E-value: 1.27e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 21356535 187 NPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHsRLLSyddrnDANFAGHVISNGSFSKILG-PGVRLG 264
Cdd:PRK07550 174 NPTGVVYPPELLHELYDLARRHGIALILDETYRDFDSGGGAPH-DLFA-----DPDWDDTLVHLYSFSKSYAlTGHRVG 246
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
80-261 |
1.32e-03 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 39.29 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 80 EISTYFTEMFksPVNCEDLIITTGASHGLHILLSTMLDFEGFVFVDEYT----YMIALDsiKHFSTVTIVPVKLNDDGV- 154
Cdd:cd01494 4 ELEEKLARLL--QPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGhgsrYWVAAE--LAGAKPVPVPVDDAGYGGl 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21356535 155 DLKDLEEKVskrrfqsKKKEFWGIYYTipTYHNPTGILfspEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSRlls 234
Cdd:cd01494 80 DVAILEELK-------AKPNVALIVIT--PNTTSGGVL---VPLKEIRKIAKEYGILLLVDAASAGGASPAPGVLIP--- 144
|
170 180
....*....|....*....|....*..
gi 21356535 235 yddrndaNFAGHVIsNGSFSKILGPGV 261
Cdd:cd01494 145 -------EGGADVV-TFSLHKNLGGEG 163
|
|
| |
