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Conserved domains on  [gi|24647123|ref|NP_650451|]
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uncharacterized protein Dmel_CG5038 [Drosophila melanogaster]

Protein Classification

transmembrane and TPR repeat-containing protein( domain architecture ID 13750405)

transmembrane and TPR repeat-containing (TMTC) protein functions as a protein O-mannosyl-transferase, catalyzing the transfer of mannosyl residues to the hydroxyl group of serine or threonine residues

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 431-675 1.72e-40

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 149.49  E-value: 1.72e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 431 QLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPA 510
Cdd:COG2956  29 DLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPD 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 511 FPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTML 590
Cdd:COG2956 109 DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELY 188

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 591 DNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYhTNLGVLYHRWDKTQEAIEA 670
Cdd:COG2956 189 LEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL-LALADLLERKEGLEAALAL 267


                ....*
gi 24647123 671 YRTAI 675
Cdd:COG2956 268 LERQL 272
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 258-331 9.51e-26

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


:

Pssm-ID: 462468  Cd Length: 75  Bit Score: 100.68  E-value: 9.51e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24647123   258 FETPTFKEVDNPVAHNEHVLTRGLSQQYLLVMNIWLMLCPHWLCYDWALGCVKLVTNIWDLRLQGVIGFYSIVL 331
Cdd:pfam08409   2 GQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 431-675 1.72e-40

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 149.49  E-value: 1.72e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 431 QLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPA 510
Cdd:COG2956  29 DLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPD 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 511 FPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTML 590
Cdd:COG2956 109 DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELY 188

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 591 DNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYhTNLGVLYHRWDKTQEAIEA 670
Cdd:COG2956 189 LEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL-LALADLLERKEGLEAALAL 267


                ....*
gi 24647123 671 YRTAI 675
Cdd:COG2956 268 LERQL 272
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 258-331 9.51e-26

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 100.68  E-value: 9.51e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24647123   258 FETPTFKEVDNPVAHNEHVLTRGLSQQYLLVMNIWLMLCPHWLCYDWALGCVKLVTNIWDLRLQGVIGFYSIVL 331
Cdd:pfam08409   2 GQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 431-671 8.80e-20

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 94.38  E-value: 8.80e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   431 QLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPA 510
Cdd:TIGR02917 520 QRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPD 599

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   511 FPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTML 590
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLL 679

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   591 DNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPhNTLYHTNLGVLYHRWDKTQEA--- 667
Cdd:TIGR02917 680 LAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAP-SSQNAIKLHRALLASGNTAEAvkt 758


                  ....
gi 24647123   668 IEAY 671
Cdd:TIGR02917 759 LEAW 762
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 458-541 8.18e-11

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 62.95  E-value: 8.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  458 GNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEK 537
Cdd:NF033920 170 GQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAEC 249


                 ....
gi 24647123  538 ALKY 541
Cdd:NF033920 250 ALAL 253
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 523-664 2.59e-08

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 53.91  E-value: 2.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  523 SAQ--GKYDKALASYEKALKYRAN---FAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGlqd 597
Cdd:PRK02603  44 SAQadGEYAEALENYEEALKLEEDpndRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRG--- 120

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24647123  598 dalRISNQALQHlpNDVSILFIRAnvlgklkhyteAEAiYKRVIELEPHNTLYHTNlgvlyhrWDKT 664
Cdd:PRK02603 121 ---EKAEEAGDQ--DEAEALFDKA-----------AEY-WKQAIRLAPNNYIEAQN-------WLKT 163
TPR_12 pfam13424
Tetratricopeptide repeat;
513-578 5.60e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 50.46  E-value: 5.60e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24647123   513 AAWMNLGIVQSAQGKYDKALASYEKAL--------KYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPR 578
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALeiarrllgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
gliding_GltE NF033758
adventurous gliding motility TPR repeat lipoprotein GltE; GltE (also called AglT) is a ...
 498-679 2.68e-06

adventurous gliding motility TPR repeat lipoprotein GltE; GltE (also called AglT) is a tetratricopeptide repeat protein with a lipoprotein signal peptide and a role in A-motility (adventurous gliding motility) in Myxococcus xanthus and other delta-proteobacteria.


Pssm-ID: 468174 [Multi-domain]  Cd Length: 411  Bit Score: 50.21  E-value: 2.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  498 EEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRA-------NFAVCYYNMGNLYLEQKRYAEALHHWq 570
Cdd:NF033758  72 ERKFKAALEADPNLAEAEYNLGVLAERQGKTDEAVARYKAALKKKPtlrqaseNLAVMAQNAGDVAGAVALYQDVLKRY- 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  571 havalnPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLY 650
Cdd:NF033758 151 ------PDDASSRARLAEIYRQTGDHDKAMELSRAALMRDPQSTTALKVMMRSYLDRKQLAMAKLVALRAVKIDQNDPEL 224

                        170       180
                 ....*....|....*....|....*....
gi 24647123  651 HTNLGVLYHRWDKTQEAIEAYRTAISISA 679
Cdd:NF033758 225 HHTVGLILLQEGDKDGARLQFKRALEVRA 253
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 546-577 4.71e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 43.59  E-value: 4.71e-06
                           10        20        30
                   ....*....|....*....|....*....|..
gi 24647123    546 AVCYYNMGNLYLEQKRYAEALHHWQHAVALNP 577
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 421-613 1.39e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 47.62  E-value: 1.39e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 421 QRATDWLNE------EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYE-SALMNLgnlyrehGQ 493
Cdd:cd24142   5 EKAEELLDQgnfelaLKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYL-------GQ 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 494 LSTAEEyirlALQAYpafpaawmNLGI------VQSAQGKYdKALASYEKALKYRANFAVCyyNMGNLYL---------E 558
Cdd:cd24142  78 LSGGEE----ALQYY--------EKGIeileeeLQALQAAS-AEAEEEAEELKRKLSSALC--ALAEIYMtdlcdepdaE 142

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 24647123 559 QKryAEALhhWQHAVALNPRQPKAWANILTMLDNKGLQDDA---LRISNQALQHLPND 613
Cdd:cd24142 143 QR--CEEL--ITKALELDPTNPEALQTLASLRISQQRPDEAkeaLRRSLELWKDLKEE 196
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 479-539 3.72e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 40.67  E-value: 3.72e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24647123  479 SALMNLGNLYREHGQLSTAEEYIRLALQAYPAFP--------AAWMNLGIVQSAQGKYDKALASYEKAL 539
Cdd:NF040586 648 AAALSLANDLRALGDADEARELAREVLDRYRRVLgedhpftlACRNNLAVLLRALGDPEEARELAEAAL 716
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 431-675 1.72e-40

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 149.49  E-value: 1.72e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 431 QLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPA 510
Cdd:COG2956  29 DLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPD 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 511 FPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTML 590
Cdd:COG2956 109 DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELY 188

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 591 DNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYhTNLGVLYHRWDKTQEAIEA 670
Cdd:COG2956 189 LEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL-LALADLLERKEGLEAALAL 267


                ....*
gi 24647123 671 YRTAI 675
Cdd:COG2956 268 LERQL 272
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
437-687 2.61e-39

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 145.53  E-value: 2.61e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 437 LQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWM 516
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 517 NLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQ 596
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 597 DDALRISNQALQHLPNDvsilfiRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAIS 676
Cdd:COG0457 161 EEALELLEKLEAAALAA------LLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALR 234

                       250
                ....*....|.
gi 24647123 677 ISAARATTARE 687
Cdd:COG0457 235 LAALALYQYRA 245
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
471-701 1.08e-38

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 143.61  E-value: 1.08e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 471 IELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYY 550
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 551 NMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHY 630
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24647123 631 TEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAARATTARENLSKLLKRLEREAQ 701
Cdd:COG0457 161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLL 231
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 458-704 6.76e-37

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 139.48  E-value: 6.76e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 458 GNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEK 537
Cdd:COG2956  22 GQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 538 ALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSIL 617
Cdd:COG2956 102 LLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARAL 181

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 618 FIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAarATTARENLSKLLKRLE 697
Cdd:COG2956 182 LLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP--SDDLLLALADLLERKE 259


                ....*..
gi 24647123 698 REAQVMQ 704
Cdd:COG2956 260 GLEAALA 266
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 420-629 6.26e-33

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 135.12  E-value: 6.26e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 420 RQRATDWLNEEQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEE 499
Cdd:COG3914  54 AAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALA 133

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 500 YIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQ 579
Cdd:COG3914 134 ALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDN 213

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24647123 580 PKAWANILTML--------------DNKGLQDDALRISNQALQHLP-NDVSILFIRANVLGKLKH 629
Cdd:COG3914 214 ADAHSNLLFALrqacdwevydrfeeLLAALARGPSELSPFALLYLPdDDPAELLALARAWAQLVA 278
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
430-610 1.60e-32

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 126.27  E-value: 1.60e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 430 EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:COG0457  28 IEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDP 107

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 510 AFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTM 589
Cdd:COG0457 108 DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAA 187

                       170       180
                ....*....|....*....|.
gi 24647123 590 LDNKGLQDDALRISNQALQHL 610
Cdd:COG0457 188 LALAAAEVLLALLLALEQALR 208
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 430-642 1.85e-32

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 126.77  E-value: 1.85e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 430 EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:COG2956  62 IRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGP 141

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 510 AFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTM 589
Cdd:COG2956 142 ENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAEL 221

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 24647123 590 LDNKGLQDDALRISNQALQHLPNDVSILFIrANVLGKLKHYTEAEAIYKRVIE 642
Cdd:COG2956 222 YEKLGDPEEALELLRKALELDPSDDLLLAL-ADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 484-704 1.48e-30

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 121.37  E-value: 1.48e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 484 LGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYA 563
Cdd:COG2956  14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 564 EALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIEL 643
Cdd:COG2956  94 RAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL 173

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24647123 644 EPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAARAtTARENLSKLLKRLEREAQVMQ 704
Cdd:COG2956 174 DPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYL-PALPRLAELYEKLGDPEEALE 233
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 447-654 1.64e-29

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 124.72  E-value: 1.64e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 447 HYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIV----- 521
Cdd:COG3914   4 AALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAallel 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 522 ----QSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQD 597
Cdd:COG3914  84 aallLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE 163

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 24647123 598 DALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNL 654
Cdd:COG3914 164 EAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 444-579 2.15e-28

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 110.67  E-value: 2.15e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 444 AKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQS 523
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 24647123 524 AQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQ 579
Cdd:COG4783  84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 447-672 1.99e-27

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 118.17  E-value: 1.99e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 447 HYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREH-------GQLSTAEEYIRLALQAYPAFPAAWMNLG 519
Cdd:COG3914  40 ALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAalllqalGRYEEALALYRRALALNPDNAEALFNLG 119

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 520 IVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDA 599
Cdd:COG3914 120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24647123 600 LRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLyHTNLGVLYHRWDKTQEAIEAYR 672
Cdd:COG3914 200 IAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSE-LSPFALLYLPDDDPAELLALAR 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 510-705 9.34e-27

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 110.20  E-value: 9.34e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 510 AFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTM 589
Cdd:COG2956   6 AAALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQD 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 590 LDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIE 669
Cdd:COG2956  86 YLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIE 165

                       170       180       190
                ....*....|....*....|....*....|....*...
gi 24647123 670 AYRTAISI--SAARATTARENLSKLLKRLEREAQVMQR 705
Cdd:COG2956 166 ALEKALKLdpDCARALLLLAELYLEQGDYEEAIAALER 203
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 258-331 9.51e-26

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 100.68  E-value: 9.51e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24647123   258 FETPTFKEVDNPVAHNEHVLTRGLSQQYLLVMNIWLMLCPHWLCYDWALGCVKLVTNIWDLRLQGVIGFYSIVL 331
Cdd:pfam08409   2 GQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 479-613 1.37e-23

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 96.80  E-value: 1.37e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 479 SALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLE 558
Cdd:COG4783   5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 24647123 559 QKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPND 613
Cdd:COG4783  85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 430-540 6.44e-23

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 94.87  E-value: 6.44e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 430 EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:COG4783  24 EALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP 103

                        90       100       110
                ....*....|....*....|....*....|.
gi 24647123 510 AFPAAWMNLGIVQSAQGKYDKALASYEKALK 540
Cdd:COG4783 104 EHPEAYLRLARAYRALGRPDEAIAALEKALE 134
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 513-647 6.28e-22

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 92.18  E-value: 6.28e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 513 AAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDN 592
Cdd:COG4783   5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 24647123 593 KGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHN 647
Cdd:COG4783  85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 403-566 3.24e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.03  E-value: 3.24e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 403 ALRILLMLLfsvmmvrtrQRATDWLNEEQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALM 482
Cdd:COG2956 112 ALRLLAEIY---------EQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALL 182

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 483 NLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVcYYNMGNLYLEQKRY 562
Cdd:COG2956 183 LLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL-LLALADLLERKEGL 261


                ....
gi 24647123 563 AEAL 566
Cdd:COG2956 262 EAAL 265
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 462-584 6.15e-21

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 88.91  E-value: 6.15e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 462 KAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKY 541
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 24647123 542 RANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWA 584
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 431-540 6.51e-21

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 88.91  E-value: 6.51e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 431 QLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPA 510
Cdd:COG4235   4 ARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPD 83

                        90       100       110
                ....*....|....*....|....*....|
gi 24647123 511 FPAAWMNLGIVQSAQGKYDKALASYEKALK 540
Cdd:COG4235  84 NPEALYLLGLAAFQQGDYAEAIAAWQKLLA 113
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 549-679 9.01e-21

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 89.10  E-value: 9.01e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 549 YYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLK 628
Cdd:COG4783   7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 24647123 629 HYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISA 679
Cdd:COG4783  87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 431-671 8.80e-20

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 94.38  E-value: 8.80e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   431 QLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPA 510
Cdd:TIGR02917 520 QRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPD 599

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   511 FPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTML 590
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLL 679

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   591 DNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPhNTLYHTNLGVLYHRWDKTQEA--- 667
Cdd:TIGR02917 680 LAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAP-SSQNAIKLHRALLASGNTAEAvkt 758


                  ....
gi 24647123   668 IEAY 671
Cdd:TIGR02917 759 LEAW 762
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 406-700 3.11e-19

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 92.45  E-value: 3.11e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   406 ILLMLLFSVMMVRTRQRATDWLNEEQLFKSALQvcpdnAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLG 485
Cdd:TIGR02917  92 VLPLLARAYLLQGKFQQVLDELPGKTLLDDEGA-----AELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLA 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   486 NLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEA 565
Cdd:TIGR02917 167 QLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEA 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   566 LHHWQHAVALNPRQPKAwANILTMLD--NKGLQD------DALRIS---------------------------NQALQHL 610
Cdd:TIGR02917 247 EKHADALLKKAPNSPLA-HYLKALVDfqKKNYEDaretlqDALKSApeylpalllagaseyqlgnleqayqylNQILKYA 325

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   611 PNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAARATT-ARENL 689
Cdd:TIGR02917 326 PNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAArTQLGI 405

                         330
                  ....*....|.
gi 24647123   690 SKLLKRLEREA 700
Cdd:TIGR02917 406 SKLSQGDPSEA 416
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 497-623 5.36e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 83.52  E-value: 5.36e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 497 AEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALN 576
Cdd:COG4235   2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 24647123 577 PRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANV 623
Cdd:COG4235  82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
487-578 6.58e-19

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 82.14  E-value: 6.58e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 487 LYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALAsYEKALKYRANFAVCYYNMGNLYLEQKRYAEAL 566
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|..
gi 24647123 567 HHWQHAVALNPR 578
Cdd:COG3063  80 AYLERALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 512-701 4.76e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 88.51  E-value: 4.76e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 512 PAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTM-- 589
Cdd:COG3914   1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAal 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 590 -------LDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWD 662
Cdd:COG3914  81 lelaallLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG 160

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 24647123 663 KTQEAIEAYRTAISISAARAtTARENLSKLLKRLEREAQ 701
Cdd:COG3914 161 RLEEAIAALRRALELDPDNA-EALNNLGNALQDLGRLEE 198
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 530-647 5.18e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 80.82  E-value: 5.18e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 530 KALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQH 609
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 24647123 610 LPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHN 647
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 430-705 1.07e-17

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 87.83  E-value: 1.07e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   430 EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:TIGR02917 485 REAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNP 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   510 AFPAAWMNLGIVQSAQGKYDKALASYEKALK-YRANFAvcYYNM-GNLYLEQKRYAEALHHWQHAVALNPRQPKAWANIL 587
Cdd:TIGR02917 565 QEIEPALALAQYYLGKGQLKKALAILNEAADaAPDSPE--AWLMlGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLA 642

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   588 TMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEA 667
Cdd:TIGR02917 643 DAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAA 722

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 24647123   668 IEAYRTAISISAARATTARenLSKLLKRLEREAQVMQR 705
Cdd:TIGR02917 723 IQAYRKALKRAPSSQNAIK--LHRALLASGNTAEAVKT 758
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 434-668 1.36e-17

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 87.45  E-value: 1.36e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   434 KSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPA 513
Cdd:TIGR02917 659 KRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQN 738

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   514 AwMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANiLTMLDNK 593
Cdd:TIGR02917 739 A-IKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNN-LAWLYLE 816

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24647123   594 GLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAI 668
Cdd:TIGR02917 817 LKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEAR 891
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
434-583 1.64e-17

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 81.89  E-value: 1.64e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 434 KSALQVCPDNAKVHYNIARLATDMGNNTKAfQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPA 513
Cdd:COG4785  30 LFAAVLALAIALADLALALAAAALAAAALA-AERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAE 108

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 514 AWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAW 583
Cdd:COG4785 109 AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERA 178
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
453-540 2.22e-16

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 74.82  E-value: 2.22e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 453 LATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYiRLALQAYPAFPAAWMNLGIVQSAQGKYDKAL 532
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                ....*...
gi 24647123 533 ASYEKALK 540
Cdd:COG3063  80 AYLERALE 87
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 436-579 3.33e-16

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 76.54  E-value: 3.33e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 436 ALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAW 515
Cdd:COG5010  12 LYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELY 91

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24647123 516 MNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQ 579
Cdd:COG5010  92 YNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPLK 155
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 420-540 7.00e-16

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 75.38  E-value: 7.00e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 420 RQRATDWLNEEQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEE 499
Cdd:COG5010  30 ALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKE 109

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 24647123 500 YIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALK 540
Cdd:COG5010 110 YYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 468-611 7.34e-16

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 75.38  E-value: 7.34e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 468 HRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAV 547
Cdd:COG5010  10 LPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE 89

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24647123 548 CYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLP 611
Cdd:COG5010  90 LYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 441-673 2.25e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 80.13  E-value: 2.25e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   441 PDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGI 520
Cdd:TIGR02917 462 PDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAG 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   521 VQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDAL 600
Cdd:TIGR02917 542 LYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAV 621

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24647123   601 RISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRT 673
Cdd:TIGR02917 622 SSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKS 694
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
480-675 5.38e-15

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 74.57  E-value: 5.38e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 480 ALMNLGNLYREHGQLStAEEYIRLALQAYPAFPA-AWMNLGIVQSAQGKYDKALASYEKALKY------RANFAVCYYNM 552
Cdd:COG4785   1 LYALALALLLALALAA-AAASKAAILLAALLFAAvLALAIALADLALALAAAALAAAALAAERidralaLPDLAQLYYER 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 553 GNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTE 632
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYEL 159

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 24647123 633 AEAIYKRVIELEPHNTLYHTNLGVLYHRWDKtQEAIEAYRTAI 675
Cdd:COG4785 160 AIADLEKALELDPNDPERALWLYLAERKLDP-EKALALLLEDW 201
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
521-612 8.37e-15

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 70.20  E-value: 8.37e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 521 VQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALhHWQHAVALNPRQPKAWANILTMLDNKGLQDDAL 600
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|..
gi 24647123 601 RISNQALQHLPN 612
Cdd:COG3063  80 AYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 493-645 2.15e-13

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 68.45  E-value: 2.15e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 493 QLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHA 572
Cdd:COG5010   1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24647123 573 VALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEP 645
Cdd:COG5010  81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
420-574 4.73e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 69.17  E-value: 4.73e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 420 RQRATDWLNEEQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEE 499
Cdd:COG4785  83 YDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIA 162

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24647123 500 YIRLALQAYPAFPAAWMNLGIVQsAQGKYDKALASYEKALkyranfavcyynmGNLYLEQKRYAEALHHWQHAVA 574
Cdd:COG4785 163 DLEKALELDPNDPERALWLYLAE-RKLDPEKALALLLEDW-------------ATAYLLQGDTEEARELFKLALA 223
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 435-694 6.94e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.04  E-value: 6.94e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   435 SALQVCPDN-AKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAypAFPA 513
Cdd:TIGR02917  12 LALSACGDQsPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSL--GYPK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   514 AWMNLGIVQSA--QGKYDKALASYEKA-LKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTML 590
Cdd:TIGR02917  90 NQVLPLLARAYllQGKFQQVLDELPGKtLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLA 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   591 DNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVL------YHRWDKT 664
Cdd:TIGR02917 170 LAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATIlieageFEEAEKH 249

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 24647123   665 QEAIEA----------YRTAISISAARATTARENLSKLLK 694
Cdd:TIGR02917 250 ADALLKkapnsplahyLKALVDFQKKNYEDARETLQDALK 289
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
430-510 4.94e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 62.50  E-value: 4.94e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 430 EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQhYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:COG3063  12 EEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90


                .
gi 24647123 510 A 510
Cdd:COG3063  91 S 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 458-695 1.36e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 68.19  E-value: 1.36e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   458 GNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEK 537
Cdd:TIGR02917 377 GDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKK 456

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   538 ALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSIL 617
Cdd:TIGR02917 457 LEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAI 536

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   618 FIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVlYHRWDK--------TQEAIEAYRTAISISAARATT----- 684
Cdd:TIGR02917 537 LALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQ-YYLGKGqlkkalaiLNEAADAAPDSPEAWLMLGRAqlaag 615

                         250
                  ....*....|....*
gi 24647123   685 ----ARENLSKLLKR 695
Cdd:TIGR02917 616 dlnkAVSSFKKLLAL 630
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 430-516 2.32e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.56  E-value: 2.32e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 430 EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:COG4235  37 LAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116


                ....*..
gi 24647123 510 AFPAAWM 516
Cdd:COG4235 117 ADAPARL 123
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 527-681 3.53e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 61.90  E-value: 3.53e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 527 KYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQA 606
Cdd:COG5010   1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24647123 607 LQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAAR 681
Cdd:COG5010  81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPLK 155
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 430-509 4.66e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 61.51  E-value: 4.66e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 430 EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:COG5010  74 LALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 436-702 5.64e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 65.88  E-value: 5.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   436 ALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAW 515
Cdd:TIGR02917 253 LLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQAR 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   516 MNLGIVQSAQGKYDKALAS---------------------------YEKALKYRA-------NFAVCYYNMGNLYLEQKR 561
Cdd:TIGR02917 333 RLLASIQLRLGRVDEAIATlspalgldpddpaalsllgeaylalgdFEKAAEYLAkateldpENAAARTQLGISKLSQGD 412

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   562 YAEALHHWQHAVALNPRQPKA-WANILTMLDNKGLqDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRV 640
Cdd:TIGR02917 413 PSEAIADLETAAQLDPELGRAdLLLILSYLRSGQF-DKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKA 491

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24647123   641 IELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAA--RATTArenLSKLLKRLEREAQV 702
Cdd:TIGR02917 492 LSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKnlRAILA---LAGLYLRTGNEEEA 552
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 458-541 8.18e-11

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 62.95  E-value: 8.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  458 GNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEK 537
Cdd:NF033920 170 GQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAEC 249


                 ....
gi 24647123  538 ALKY 541
Cdd:NF033920 250 ALAL 253
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 430-511 1.39e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.82  E-value: 1.39e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 430 EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:COG4783  58 IVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137


                ..
gi 24647123 510 AF 511
Cdd:COG4783 138 DD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
555-680 5.52e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 56.72  E-value: 5.52e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 555 LYLEQKRYAEALHHWQHAVALNPRQPKAWANiltmldnkglqddalrisnqalqhlpndvsilfiRANVLGKLKHYTEAE 634
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNN----------------------------------LGLLLLEQGRYDEAI 46

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 24647123 635 AiYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAA 680
Cdd:COG3063  47 A-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 458-540 6.62e-10

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 56.92  E-value: 6.62e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 458 GNNTKAFQHYHRAIELYPNYE---SALMNLGNLYREHGQLSTAEEYIRLALQAYPA---FPAAWMNLGIVQSAQGKYDKA 531
Cdd:COG1729   7 GDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYDKA 86


                ....*....
gi 24647123 532 LASYEKALK 540
Cdd:COG1729  87 RATLEELIK 95
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 528-675 1.99e-09

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 60.77  E-value: 1.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   528 YDKALASYEKAL---KYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISN 604
Cdd:TIGR00990 310 YEEAARAFEKALdlgKLGEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFD 389

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24647123   605 QALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAI 675
Cdd:TIGR00990 390 KALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCK 460
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 525-645 2.90e-09

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 55.00  E-value: 2.90e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 525 QGKYDKALASYEKALK------YRANfavCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAwaniltmldnkglqDD 598
Cdd:COG1729   6 AGDYDEAIAAFKAFLKrypnspLAPD---ALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKA--------------PD 68

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 24647123 599 AlrisnqalqhlpndvsiLFIRANVLGKLKHYTEAEAIYKRVIELEP 645
Cdd:COG1729  69 A-----------------LLKLGLSYLELGDYDKARATLEELIKKYP 98
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 488-582 4.71e-09

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 54.61  E-value: 4.71e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 488 YREHGQLSTAEEYIRLALQAYPA---FPAAWMNLGIVQSAQGKYDKALASYEKALKYRAN---FAVCYYNMGNLYLEQKR 561
Cdd:COG1729   3 LLKAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGD 82

                        90       100
                ....*....|....*....|.
gi 24647123 562 YAEALHHWQHAVALNPRQPKA 582
Cdd:COG1729  83 YDKARATLEELIKKYPDSEAA 103
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 430-606 6.33e-09

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 59.23  E-value: 6.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   430 EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:TIGR00990 385 EEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFP 464

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   510 AFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGN-------LYLEQKRYAEALHHWQHAVALNPRQPKA 582
Cdd:TIGR00990 465 EAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLPlinkalaLFQWKQDFIEAENLCEKALIIDPECDIA 544

                         170       180
                  ....*....|....*....|....
gi 24647123   583 WANILTMLDNKGLQDDALRISNQA 606
Cdd:TIGR00990 545 VATMAQLLLQQGDVDEALKLFERA 568
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 613-701 1.63e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 1.63e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 613 DVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAARAtTARENLSKL 692
Cdd:COG4783   3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP-EARLNLGLA 81


                ....*....
gi 24647123 693 LKRLEREAQ 701
Cdd:COG4783  82 LLKAGDYDE 90
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 434-537 1.68e-08

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 55.81  E-value: 1.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   434 KSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPN-----------------YESA---------------- 480
Cdd:TIGR02521  55 DKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNngdvlnnygtflcqqgkYEQAmqqfeqaiedplypqp 134

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   481 ---LMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEK 537
Cdd:TIGR02521 135 arsLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYKDARAYLER 194
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 430-514 1.87e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 52.69  E-value: 1.87e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 430 EQLFKSALQVCPDN---AKVHYNIARLATDMGNNTKAFQHYHRAIELYPN---YESALMNLGNLYREHGQLSTAEEYIRL 503
Cdd:COG1729  13 IAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYDKARATLEE 92

                        90
                ....*....|.
gi 24647123 504 ALQAYPAFPAA 514
Cdd:COG1729  93 LIKKYPDSEAA 103
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 523-664 2.59e-08

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 53.91  E-value: 2.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  523 SAQ--GKYDKALASYEKALKYRAN---FAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGlqd 597
Cdd:PRK02603  44 SAQadGEYAEALENYEEALKLEEDpndRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRG--- 120

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24647123  598 dalRISNQALQHlpNDVSILFIRAnvlgklkhyteAEAiYKRVIELEPHNTLYHTNlgvlyhrWDKT 664
Cdd:PRK02603 121 ---EKAEEAGDQ--DEAEALFDKA-----------AEY-WKQAIRLAPNNYIEAQN-------WLKT 163
TPR_12 pfam13424
Tetratricopeptide repeat;
513-578 5.60e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 50.46  E-value: 5.60e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24647123   513 AAWMNLGIVQSAQGKYDKALASYEKAL--------KYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPR 578
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALeiarrllgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
623-701 9.99e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.17  E-value: 9.99e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24647123 623 VLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIeAYRTAISISAARAtTARENLSKLLKRLEREAQ 701
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNA-EALLNLAELLLELGDYDE 77
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 490-701 2.00e-07

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 54.70  E-value: 2.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   490 EHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANfavcYYNMG--NLYLEQKRYAEALH 567
Cdd:PRK11447  281 DSGQGGKAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPH----SSNRDkwESLLKVNRYWLLIQ 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   568 HWQHAV-ALNPRQpkawaniltmldnkglqddALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPH 646
Cdd:PRK11447  357 QGDAALkANNLAQ-------------------AERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPG 417

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 24647123   647 NTLYHTNLGVLYHRwdKTQEAIEAYRTaiSISAARATTARENLSKL-LKRLEREAQ 701
Cdd:PRK11447  418 NTNAVRGLANLYRQ--QSPEKALAFIA--SLSASQRRSIDDIERSLqNDRLAQQAE 469
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
515-704 2.96e-07

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 52.19  E-value: 2.96e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 515 WMNLGIVQSAQGKYDKALASYEKALK--YRANFAVCyYNMGNLYLEQKRYAEALHHWQHAVALNP--RQPkawaniltml 590
Cdd:COG4700  92 RVRLADALLELGRYDEAIELYEEALTgiFADDPHIL-LGLAQALFELGRYAEALETLEKLIAKNPdfKSS---------- 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 591 dnkglqddalrisnqalqhlpnDVSILFIRAnvLGKLKHYTEAEAIYKRVIELEPH-NTLYHtnLGVLYHRWDKTQEAIE 669
Cdd:COG4700 161 ----------------------DAHLLYARA--LEALGDLEAAEAELEALARRYSGpEARYR--YAKFLARQGRTAEAKE 214

                       170       180       190
                ....*....|....*....|....*....|....*
gi 24647123 670 AYRTAISISAARATTARENLSKLLKRLEREAQVMQ 704
Cdd:COG4700 215 LLEEILDEAKHMPKHYRRLNREWIREAKKLLKSLR 249
TPR_11 pfam13414
TPR repeat;
524-559 4.27e-07

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 46.70  E-value: 4.27e-07
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 24647123   524 AQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQ 559
Cdd:pfam13414   6 EQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 434-697 1.20e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.91  E-value: 1.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   434 KSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPA 513
Cdd:TIGR00990 355 SKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIF 434

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   514 AWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLdNK 593
Cdd:TIGR00990 435 SHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLPLI-NK 513

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   594 GLqddalrisnqALQHLPNDvsilfiranvlgklkhYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRT 673
Cdd:TIGR00990 514 AL----------ALFQWKQD----------------FIEAENLCEKALIIDPECDIAVATMAQLLLQQGDVDEALKLFER 567

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 24647123   674 AI-----------SISAARATTA----RENLSKLLKRLE 697
Cdd:TIGR00990 568 AAelartegelvqAISYAEATRTqiqvQEDYPVLASKLQ 606
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 401-701 1.24e-06

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 51.06  E-value: 1.24e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 401 RTALRILLMLLFSVMMVRTRQ-----RATDWLNEEQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYP 475
Cdd:COG3071   2 RRLLWLLLLLAAAVLLAALLEgllalAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAP 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 476 NYESA-LMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNM-- 552
Cdd:COG3071  82 EAELAvLLTRAELLLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHKALSAEEAQALer 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 553 ---GNLYLEQKRYAEALH-HWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDvsiLFIRANVLGKLK 628
Cdd:COG3071 162 rayLGLLRQAARDAEALKaLWKALPRAERRDPELAAAYARALIALGDHDEAERLLREALKRQWDP---RLVRLYGRLQGG 238

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24647123 629 HYTEAEAIYKRVIELEPHNTLYHTNLGVLYHR---WDKtqeAIEAYRTAISISAARAttARENLSKLLKRLEREAQ 701
Cdd:COG3071 239 DPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRnqlWGK---AREYLEAALALRPSAE--AYAELARLLEQLGDPEE 309
TPR_12 pfam13424
Tetratricopeptide repeat;
444-510 1.70e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 46.23  E-value: 1.70e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24647123   444 AKVHYNIARLATDMGNNTKAFQHYHRAIELY--------PNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPA 510
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
gliding_GltE NF033758
adventurous gliding motility TPR repeat lipoprotein GltE; GltE (also called AglT) is a ...
 498-679 2.68e-06

adventurous gliding motility TPR repeat lipoprotein GltE; GltE (also called AglT) is a tetratricopeptide repeat protein with a lipoprotein signal peptide and a role in A-motility (adventurous gliding motility) in Myxococcus xanthus and other delta-proteobacteria.


Pssm-ID: 468174 [Multi-domain]  Cd Length: 411  Bit Score: 50.21  E-value: 2.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  498 EEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRA-------NFAVCYYNMGNLYLEQKRYAEALHHWq 570
Cdd:NF033758  72 ERKFKAALEADPNLAEAEYNLGVLAERQGKTDEAVARYKAALKKKPtlrqaseNLAVMAQNAGDVAGAVALYQDVLKRY- 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  571 havalnPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLY 650
Cdd:NF033758 151 ------PDDASSRARLAEIYRQTGDHDKAMELSRAALMRDPQSTTALKVMMRSYLDRKQLAMAKLVALRAVKIDQNDPEL 224

                        170       180
                 ....*....|....*....|....*....
gi 24647123  651 HTNLGVLYHRWDKTQEAIEAYRTAISISA 679
Cdd:NF033758 225 HHTVGLILLQEGDKDGARLQFKRALEVRA 253
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
442-585 2.73e-06

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 49.11  E-value: 2.73e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 442 DNAKVHYNIARLATDMGNNTKAFQHYHRAIE-LYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAF--PAAWMNL 518
Cdd:COG4700  87 DTVQNRVRLADALLELGRYDEAIELYEEALTgIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFksSDAHLLY 166

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24647123 519 GIVQSAQGKYDKALASYEKALKYRANF-AVCYYNMgnLYLEQKRYAEA-------LHHWQHAVALNPRQPKAWAN 585
Cdd:COG4700 167 ARALEALGDLEAAEAELEALARRYSGPeARYRYAK--FLARQGRTAEAkelleeiLDEAKHMPKHYRRLNREWIR 239
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 425-540 2.76e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 2.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   425 DWLNEEQLFKSALQVCPDNAKVHYNIARLATDmGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLA 504
Cdd:TIGR02917 785 DYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLE-LKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKA 863

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 24647123   505 LQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALK 540
Cdd:TIGR02917 864 VNIAPEAAAIRYHLALALLATGRKAEARKELDKLLN 899
TPR_1 pfam00515
Tetratricopeptide repeat;
546-577 3.15e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 43.95  E-value: 3.15e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 24647123   546 AVCYYNMGNLYLEQKRYAEALHHWQHAVALNP 577
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
TPR_1 pfam00515
Tetratricopeptide repeat;
512-545 3.76e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 43.95  E-value: 3.76e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 24647123   512 PAAWMNLGIVQSAQGKYDKALASYEKALKYRANF 545
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 442-508 4.04e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 47.74  E-value: 4.04e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24647123  442 DNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLY-------REHGQLSTAEEYIRLALQAY 508
Cdd:PRK02603  70 DRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYhkrgekaEEAGDQDEAEALFDKAAEYW 143
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 546-577 4.71e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 43.59  E-value: 4.71e-06
                           10        20        30
                   ....*....|....*....|....*....|..
gi 24647123    546 AVCYYNMGNLYLEQKRYAEALHHWQHAVALNP 577
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 448-540 6.35e-06

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 45.73  E-value: 6.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   448 YNIARLATDMGNNTKAFQHYHRAIELYPNYE---SALMNLGNLYREHGQLSTAEEYIRLALQAYPAF---PAAWMNLGIV 521
Cdd:TIGR02795   4 YDAALLVLKAGDYADAIQAFQAFLKKYPKSTyapNAHYWLGEAYYAQGDYADAAKAFLAVVKKYPKSpkaPDALLKLGMS 83

                          90
                  ....*....|....*....
gi 24647123   522 QSAQGKYDKALASYEKALK 540
Cdd:TIGR02795  84 LQELGDKEKAKATLQQVIK 102
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 512-545 1.27e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.43  E-value: 1.27e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 24647123    512 PAAWMNLGIVQSAQGKYDKALASYEKALKYRANF 545
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 421-613 1.39e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 47.62  E-value: 1.39e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 421 QRATDWLNE------EQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYE-SALMNLgnlyrehGQ 493
Cdd:cd24142   5 EKAEELLDQgnfelaLKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYL-------GQ 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 494 LSTAEEyirlALQAYpafpaawmNLGI------VQSAQGKYdKALASYEKALKYRANFAVCyyNMGNLYL---------E 558
Cdd:cd24142  78 LSGGEE----ALQYY--------EKGIeileeeLQALQAAS-AEAEEEAEELKRKLSSALC--ALAEIYMtdlcdepdaE 142

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 24647123 559 QKryAEALhhWQHAVALNPRQPKAWANILTMLDNKGLQDDA---LRISNQALQHLPND 613
Cdd:cd24142 143 QR--CEEL--ITKALELDPTNPEALQTLASLRISQQRPDEAkeaLRRSLELWKDLKEE 196
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 454-647 1.77e-05

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 48.16  E-value: 1.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   454 ATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFP--AAWMNLgiVQS-------A 524
Cdd:PRK11447  279 AVDSGQGGKAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPHSSnrDKWESL--LKVnrywlliQ 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   525 QGkyDKALAS---------YEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNP------------------ 577
Cdd:PRK11447  357 QG--DAALKAnnlaqaerlYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPgntnavrglanlyrqqsp 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   578 ------------RQPKAWANILTMLDNKGLQDDALRISN------------QALQHLPNDVSILFIRANVLGKLKHYTEA 633
Cdd:PRK11447  435 ekalafiaslsaSQRRSIDDIERSLQNDRLAQQAEALENqgkwaqaaelqrQRLALDPGSVWLTYRLAQDLRQAGQRSQA 514

                         250
                  ....*....|....
gi 24647123   634 EAIYKRVIELEPHN 647
Cdd:PRK11447  515 DALMRRLAQQKPND 528
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 482-540 1.90e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 43.09  E-value: 1.90e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24647123   482 MNLGNLYREHGQLSTAEEYIRLALQAYPAFP---AAWMNLGIVQSAQGKYDKALASYEKALK 540
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPdaaAALLLLGLAALRQGRLAEAAAAYRAALR 62
ycf3 CHL00033
photosystem I assembly protein Ycf3
 523-596 1.95e-05

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 45.38  E-value: 1.95e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  523 SAQ--GKYDKALASYEKALK-----YRANFAVcyYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGL 595
Cdd:CHL00033  44 SAQseGEYAEALQNYYEAMRleidpYDRSYIL--YNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMAVICHYRGE 121


                 .
gi 24647123  596 Q 596
Cdd:CHL00033 122 Q 122
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 546-578 2.30e-05

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 41.74  E-value: 2.30e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 24647123   546 AVCYYNMGNLYLEQKRYAEALHHWQHAVALNPR 578
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 517-577 4.99e-05

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 44.28  E-value: 4.99e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24647123  517 NLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAE--------------ALHHWQHAVALNP 577
Cdd:PRK02603  77 NMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGEKAEeagdqdeaealfdkAAEYWKQAIRLAP 151
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 486-612 6.63e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 45.67  E-value: 6.63e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 486 NLYREHGQLSTAEEYIRLALQAYPAfPAAWMNLGivQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEA 565
Cdd:COG3071 201 RALIALGDHDEAERLLREALKRQWD-PRLVRLYG--RLQGGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKA 277

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 24647123 566 LHHWQHAVALNPRqPKAWANILTMLDNKGLQDDALRISNQALQHLPN 612
Cdd:COG3071 278 REYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 597-705 7.76e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 45.31  E-value: 7.76e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 597 DDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNT----LYhtnLGvlyhrwdktQ-----EA 667
Cdd:cd24142  17 ELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyekyLY---LG---------QlsggeEA 84

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 24647123 668 IEAYRTAISIsaarATTARENLSKLLKRLEREAQVMQR 705
Cdd:cd24142  85 LQYYEKGIEI----LEEELQALQAASAEAEEEAEELKR 118
TPR_19 pfam14559
Tetratricopeptide repeat;
525-584 1.10e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 40.65  E-value: 1.10e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   525 QGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWA 584
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
TPR_1 pfam00515
Tetratricopeptide repeat;
444-477 1.14e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.71  E-value: 1.14e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 24647123   444 AKVHYNIARLATDMGNNTKAFQHYHRAIELYPNY 477
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 556-692 2.42e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 2.42e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 556 YLEQKRYAEALHHWQHAVALNPRQPkawaniltmldnkgLQDDALrisnqalqhlpndvsilFIRANVLGKLKHYTEAEA 635
Cdd:COG1729   3 LLKAGDYDEAIAAFKAFLKRYPNSP--------------LAPDAL-----------------YWLGEAYYALGDYDEAAE 51

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24647123 636 IYKRVIELEPHNTLYHT---NLGVLYHRWDKTQEAIEAYRTAISI--SAARATTARENLSKL 692
Cdd:COG1729  52 AFEKLLKRYPDSPKAPDallKLGLSYLELGDYDKARATLEELIKKypDSEAAKEARARLARL 113
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 512-541 2.55e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 38.66  E-value: 2.55e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 24647123   512 PAAWMNLGIVQSAQGKYDKALASYEKALKY 541
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALEL 30
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 516-580 2.80e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.63  E-value: 2.80e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24647123   516 MNLGIVQSAQGKYDKALASYEKALKYRANFAVC---YYNMGNLYLEQKRYAEALHHWQHAVALNPRQP 580
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPDAaaaLLLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 448-509 4.45e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 4.45e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24647123   448 YNIARLATDMGNNTKAFQHYHRAIELYPNYES---ALMNLGNLYREHGQLSTAEEYIRLALQAYP 509
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPDaaaALLLLGLAALRQGRLAEAAAAYRAALRAAP 65
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 444-477 6.03e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 6.03e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 24647123    444 AKVHYNIARLATDMGNNTKAFQHYHRAIELYPNY 477
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_19 pfam14559
Tetratricopeptide repeat;
458-516 6.21e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 38.72  E-value: 6.21e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 24647123   458 GNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWM 516
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
ycf3 CHL00033
photosystem I assembly protein Ycf3
 448-509 6.50e-04

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 41.15  E-value: 6.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  448 YNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYR-------EHGQLSTAE-------EY----IRLALQAYP 509
Cdd:CHL00033  76 YNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMAVICHyrgeqaiEQGDSEIAEawfdqaaEYwkqaIALAPGNYI 155
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 451-590 6.71e-04

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 42.30  E-value: 6.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   451 ARLATDMGNNTKAFQHYHRAIELYPNYE-----SALMNLGNLYREHGQLSTAE----EYIRLALQAYPAFPAAW--MNLG 519
Cdd:pfam17874   8 AQLAISKGDAERALELAEQALALLPEDDllargLATFVLGEAYLCLGDLDAALqamrEAEALARRADSPHVTLWalLQQG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123   520 IVQSAQGKYDKALASYEKALKY-------RANFAVCYY-NMGNLYLEQKRYAEALHHWQHAVALN-PRQPKAWANILTML 590
Cdd:pfam17874  88 EILRAQGRLHQALETYQQALQLardhglqHLPLHGFLLvGLADLLYEWNDLEEAEQHAQQGIQLGrQWEPDAAVDAYVLL 167
COG3899 COG3899
Predicted ATPase [General function prediction only];
446-575 2.16e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 41.38  E-value: 2.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  446 VHYNI--ARLATDMGNNTKAFQHYHRAIELYP-----NYESAL-MNLGNLYREHGQLSTAEEYIRLALQAY--------- 508
Cdd:COG3899  705 ARLLLraARRALARGAYAEALRYLERALELLPpdpeeEYRLALlLELAEALYLAGRFEEAEALLERALAARalaalaalr 784

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24647123  509 ----PAFPAAWMNLGIVQsaQGKYDKALASYEKALK------YRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVAL 575
Cdd:COG3899  785 hgnpPASARAYANLGLLL--LGDYEEAYEFGELALAlaerlgDRRLEARALFNLGFILHWLGPLREALELLREALEA 859
TPR_11 pfam13414
TPR repeat;
553-586 2.31e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 2.31e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 24647123   553 GNLYLEQKRYAEALHHWQHAVALNPRQPKAWANI 586
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNL 34
TPR_11 pfam13414
TPR repeat;
456-492 2.58e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.91  E-value: 2.58e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 24647123   456 DMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHG 492
Cdd:pfam13414   6 EQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_19 pfam14559
Tetratricopeptide repeat;
597-652 3.06e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.41  E-value: 3.06e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 24647123   597 DDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHT 652
Cdd:pfam14559   5 AEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 431-510 3.13e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 40.28  E-value: 3.13e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 431 QLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMnLGNLYREHGQLSTAEEYIRLALQAYPA 510
Cdd:COG3071 245 KRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAE-LARLLEQLGDPEEAAEHYRKALALALG 323
ycf3 CHL00033
photosystem I assembly protein Ycf3
 458-577 3.21e-03

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 38.84  E-value: 3.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  458 GNNTKAFQHYHRAIELYPN-YESA--LMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGkydkalas 534
Cdd:CHL00033  49 GEYAEALQNYYEAMRLEIDpYDRSyiLYNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMAVICHYRG-------- 120

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 24647123  535 yEKALKyranfavcyynMGNLYLEQKRYAEALHHWQHAVALNP 577
Cdd:CHL00033 121 -EQAIE-----------QGDSEIAEAWFDQAAEYWKQAIALAP 151
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 479-539 3.72e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 40.67  E-value: 3.72e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24647123  479 SALMNLGNLYREHGQLSTAEEYIRLALQAYPAFP--------AAWMNLGIVQSAQGKYDKALASYEKAL 539
Cdd:NF040586 648 AAALSLANDLRALGDADEARELAREVLDRYRRVLgedhpftlACRNNLAVLLRALGDPEEARELAEAAL 716
TPR_17 pfam13431
Tetratricopeptide repeat;
535-566 3.95e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 35.21  E-value: 3.95e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 24647123   535 YEKALKYRANFAVCYYNMGNLYLEQKRYAEAL 566
Cdd:pfam13431   2 YLKALELDPNNADAYYNLAVLLLELGQSETAL 33
TPR_19 pfam14559
Tetratricopeptide repeat;
492-544 4.15e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.41  E-value: 4.15e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 24647123   492 GQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRAN 544
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPD 54
TPR_17 pfam13431
Tetratricopeptide repeat;
469-499 5.86e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 34.83  E-value: 5.86e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 24647123   469 RAIELYPNYESALMNLGNLYREHGQLSTAEE 499
Cdd:pfam13431   4 KALELDPNNADAYYNLAVLLLELGQSETALQ 34
TPR_8 pfam13181
Tetratricopeptide repeat;
514-544 5.94e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 34.68  E-value: 5.94e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 24647123   514 AWMNLGIVQSAQGKYDKALASYEKALKYRAN 544
Cdd:pfam13181   3 AYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_12 pfam13424
Tetratricopeptide repeat;
615-677 6.12e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.21  E-value: 6.12e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24647123   615 SILFIRANVLGKLKHYTEAEAIYKRVIEL-----EPHNTLY---HTNLGVLYHRWDKTQEAIEAYRTAISI 677
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIarrllGPDHPLTattLLNLGRLYLELGRYEEALELLERALAL 74
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 400-575 6.64e-03

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 39.25  E-value: 6.64e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 400 WRTALRILLMLLfsvmMVRTRQRATDWLNEEQLFKSALQVCpdnAKVHyNIARLATDMGNNTKAFQH-------YHRAIe 472
Cdd:cd24145  97 IKRDLRISIKLG----ELNKDSELGKWELRERLLKKAVEIL---LKLG-ELWMSPSEVGAFLEELATaydlygrFCLAL- 167

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123 473 lyPNYESALMNLGNLYRE----HG-------QLSTAEEYIRLALQAYPAFPAAWMN---LGIVQSAQGKYDKALASYEKA 538
Cdd:cd24145 168 --PLYMQALSLKGQILLSqancHSlvlmnneAAELALHALRKPLSSTLIEASRLPQksrDQLLEAALKWAQKALDVAKSI 245

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 24647123 539 LKYRAN------FAVCYYNMGNLYLEQKRYAEALHHWQHAVAL 575
Cdd:cd24145 246 KPKDRDpecdqaCALALYNLGVIAEMLGNLDEARKLYKEAISL 288
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 444-476 6.69e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 34.81  E-value: 6.69e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 24647123   444 AKVHYNIARLATDMGNNTKAFQHYHRAIELYPN 476
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
PRK12370 PRK12370
HilA/EilA family virulence transcriptional regulator;
480-658 7.06e-03

HilA/EilA family virulence transcriptional regulator;


Pssm-ID: 237080 [Multi-domain]  Cd Length: 553  Bit Score: 39.45  E-value: 7.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  480 ALMNLGnLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQ 559
Cdd:PRK12370 307 SMAQMG-IFDKQNAMIKAKEHAIKATELDHNNPQALGLLGLINTIHSEYIVGSLLFKQANLLSPISADIKYYYGWNLFMA 385

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123  560 KRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRIS-NQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYK 638
Cdd:PRK12370 386 GQLEEALQTINECLKLDPTRAAAGITKLWITYYHTGIDDAIRLGdELRSQHLQDNPILLSMQVMFLSLKGKHELARKLTK 465

                        170       180
                 ....*....|....*....|
gi 24647123  639 rviELEPHNTLYHTNLGVLY 658
Cdd:PRK12370 466 ---EISTQEITGLIAVNLLY 482
BTAD smart01043
Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. ...
 541-610 9.76e-03

Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.


Pssm-ID: 198111 [Multi-domain]  Cd Length: 145  Bit Score: 37.28  E-value: 9.76e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647123    541 YRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHL 610
Cdd:smart01043  56 LRELRLEALEALAEALLALGRHEEALALLERLLALDPLRERLHRLLMRALYRAGRRAEALRAYRRLRRLL 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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