|
Name |
Accession |
Description |
Interval |
E-value |
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
185-381 |
7.51e-122 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 349.89 E-value: 7.51e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 185 DYRNSVIVARNPGVAKKANSYAERLRLGLAVIHGEQKETDADEVDGRYSPPPTRNstpqhaptssarqRTTSVSVGVPEH 264
Cdd:pfam14572 1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRS-------------RTVSRSLGLPEI 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 265 IVKVKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPH 344
Cdd:pfam14572 68 IPKEKPPMTVVGDVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPH 147
|
170 180 190
....*....|....*....|....*....|....*..
gi 24651454 345 EIQKLQCHKIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:pfam14572 148 EIQKMQCHKIKTIDISQLIAEAIRRIHNGESMSYLFR 184
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
27-381 |
5.41e-112 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 329.71 E-value: 5.41e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 27 SDIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSS 106
Cdd:COG0462 2 KDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 107 ARSIVGVIPYLPYSKQ-CKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESipD 185
Cdd:COG0462 82 ARRITAVIPYYGYARQdRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK--D 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 186 YRNSVIVARNPGVAKKANSYAERLRLGLAVIHgeqKEtdadevdgrysppptrnstpqhaptssaRQRTTSVSVgvpehi 265
Cdd:COG0462 160 LEDLVVVSPDVGGVKRARAFAKRLGAPLAIID---KR----------------------------RPGANEVEV------ 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 266 vkvkppLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHE 345
Cdd:COG0462 203 ------MNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLP 276
|
330 340 350
....*....|....*....|....*....|....*.
gi 24651454 346 IQKlQCHKIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:COG0462 277 EEK-RCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
29-381 |
9.01e-101 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 300.88 E-value: 9.01e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 29 IVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSAR 108
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 109 SIVGVIPYLPYSKQ-CKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESipDYR 187
Cdd:PRK01259 81 RITAVIPYFGYARQdRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK--NLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 188 NSVIVARNPGVAKKANSYAERLRLGLAVIhgeqketdadevDGRysppptrnstpqhaptssaRQRTTSVSVgvpehivk 267
Cdd:PRK01259 159 NLVVVSPDVGGVVRARALAKRLDADLAII------------DKR-------------------RPRANVSEV-------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 268 vkppLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEIQ 347
Cdd:PRK01259 200 ----MNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEE 275
|
330 340 350
....*....|....*....|....*....|....
gi 24651454 348 KLQCHKIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:PRK01259 276 AKKCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
29-381 |
4.47e-93 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 281.47 E-value: 4.47e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 29 IVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDA-NNNIMELLIMAYACKTSSA 107
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIQQSTSAPvNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 108 RSIVGVIPYLPYSKQCKMRKRG-CIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDy 186
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSRePISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 187 rNSVIVARNPGVAKKANSYAERLRLGLAVIHGEqketdadevdgRYSPPPTrnstpqhaptssarqrttsvsvgvpehiV 266
Cdd:TIGR01251 160 -NPVVVSPDAGGVERAKKVADALGCPLAIIDKR-----------RISATNE----------------------------V 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 267 KVKPpltIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEI 346
Cdd:TIGR01251 200 EVMN---LVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEK 276
|
330 340 350
....*....|....*....|....*....|....*
gi 24651454 347 qklQCHKIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:TIGR01251 277 ---HKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
29-144 |
3.87e-50 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 164.13 E-value: 3.87e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 29 IVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSAR 108
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 24651454 109 SIVGVIPYLPYSKQCKM-RKRGCIVSKLLAKMMCTSG 144
Cdd:pfam13793 81 RITAVIPYFGYARQDRKdKPREPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
171-341 |
5.65e-12 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 62.41 E-value: 5.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 171 ASPFLLQYIQESIPDyrNSVIVARNPGVAKKANSYAERLRLGLAVIHGEqketdadevdgRYSPPPTRnstpqhaptssa 250
Cdd:cd06223 1 AGRLLAEEIREDLLE--PDVVVGILRGGLPLAAALARALGLPLAFIRKE-----------RKGPGRTP------------ 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 251 rqrttsvsvgvpehIVKVKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAprQLDE 330
Cdd:cd06223 56 --------------SEPYGLELPLGGDVKGKRVLLVDDVIATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELA 119
|
170
....*....|.
gi 24651454 331 SPIDEIVVTNT 341
Cdd:cd06223 120 SPGDPVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
185-381 |
7.51e-122 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 349.89 E-value: 7.51e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 185 DYRNSVIVARNPGVAKKANSYAERLRLGLAVIHGEQKETDADEVDGRYSPPPTRNstpqhaptssarqRTTSVSVGVPEH 264
Cdd:pfam14572 1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRS-------------RTVSRSLGLPEI 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 265 IVKVKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPH 344
Cdd:pfam14572 68 IPKEKPPMTVVGDVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPH 147
|
170 180 190
....*....|....*....|....*....|....*..
gi 24651454 345 EIQKLQCHKIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:pfam14572 148 EIQKMQCHKIKTIDISQLIAEAIRRIHNGESMSYLFR 184
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
27-381 |
5.41e-112 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 329.71 E-value: 5.41e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 27 SDIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSS 106
Cdd:COG0462 2 KDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 107 ARSIVGVIPYLPYSKQ-CKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESipD 185
Cdd:COG0462 82 ARRITAVIPYYGYARQdRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK--D 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 186 YRNSVIVARNPGVAKKANSYAERLRLGLAVIHgeqKEtdadevdgrysppptrnstpqhaptssaRQRTTSVSVgvpehi 265
Cdd:COG0462 160 LEDLVVVSPDVGGVKRARAFAKRLGAPLAIID---KR----------------------------RPGANEVEV------ 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 266 vkvkppLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHE 345
Cdd:COG0462 203 ------MNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLP 276
|
330 340 350
....*....|....*....|....*....|....*.
gi 24651454 346 IQKlQCHKIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:COG0462 277 EEK-RCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
29-381 |
9.01e-101 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 300.88 E-value: 9.01e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 29 IVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSAR 108
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 109 SIVGVIPYLPYSKQ-CKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESipDYR 187
Cdd:PRK01259 81 RITAVIPYFGYARQdRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK--NLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 188 NSVIVARNPGVAKKANSYAERLRLGLAVIhgeqketdadevDGRysppptrnstpqhaptssaRQRTTSVSVgvpehivk 267
Cdd:PRK01259 159 NLVVVSPDVGGVVRARALAKRLDADLAII------------DKR-------------------RPRANVSEV-------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 268 vkppLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEIQ 347
Cdd:PRK01259 200 ----MNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEE 275
|
330 340 350
....*....|....*....|....*....|....
gi 24651454 348 KLQCHKIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:PRK01259 276 AKKCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
29-381 |
4.47e-93 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 281.47 E-value: 4.47e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 29 IVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDA-NNNIMELLIMAYACKTSSA 107
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIQQSTSAPvNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 108 RSIVGVIPYLPYSKQCKMRKRG-CIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDy 186
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSRePISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 187 rNSVIVARNPGVAKKANSYAERLRLGLAVIHGEqketdadevdgRYSPPPTrnstpqhaptssarqrttsvsvgvpehiV 266
Cdd:TIGR01251 160 -NPVVVSPDAGGVERAKKVADALGCPLAIIDKR-----------RISATNE----------------------------V 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 267 KVKPpltIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEI 346
Cdd:TIGR01251 200 EVMN---LVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEK 276
|
330 340 350
....*....|....*....|....*....|....*
gi 24651454 347 qklQCHKIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:TIGR01251 277 ---HKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
27-380 |
2.48e-70 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 223.65 E-value: 2.48e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 27 SDIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSS 106
Cdd:PRK04923 5 RNLLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 107 ARSIVGVIPYLPYSKQ-CKMRK-RGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESIp 184
Cdd:PRK04923 85 AASVTAVIPYFGYSRQdRRMRSsRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIWRAY- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 185 DYRNSVIVARNPGVAKKANSYAERLrlglavihgeqKETDADEVDGRysppptrnstpqhaptssaRQRTTSVSVgvpeh 264
Cdd:PRK04923 164 GTDNLIVVSPDVGGVVRARAVAKRL-----------DDADLAIIDKR-------------------RPRANVATV----- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 265 ivkvkppLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPH 344
Cdd:PRK04923 209 -------MNIIGDVQGKTCVLVDDLVDTAGTLCAAAAALKQRGALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPL 281
|
330 340 350
....*....|....*....|....*....|....*.
gi 24651454 345 EIQKLQCHKIKTIDISILIAEAIRRIHNKESMSYLF 380
Cdd:PRK04923 282 SEAARACAKIRQLSVAELLAETIRRIAFGESVSSLY 317
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
40-380 |
1.70e-69 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 220.98 E-value: 1.70e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 40 LANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSARSIVGVIPYLPY 119
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 120 SKQ-CKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDyRNSVIVARNPGV 198
Cdd:PRK03092 81 ARQdKKHRGREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKYDL-DNVTVVSPDAGR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 199 AKKANSYAERL-RLGLAVIHgeqketdadevdgrysppPTRNSTpqhaptssarqrttsvsvgVPEHiVKVKpplTIVGD 277
Cdd:PRK03092 160 VRVAEQWADRLgGAPLAFIH------------------KTRDPT-------------------VPNQ-VVAN---RVVGD 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 278 VSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEIQKlQCHKIKTI 357
Cdd:PRK03092 199 VEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIAATHGVLSGPAAERLKNCGAREVVVTDTLPIPEEK-RFDKLTVL 277
|
330 340
....*....|....*....|...
gi 24651454 358 DISILIAEAIRRIHNKESMSYLF 380
Cdd:PRK03092 278 SIAPLLARAIREVFEDGSVTSLF 300
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
38-381 |
2.40e-69 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 220.34 E-value: 2.40e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 38 PDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSARSIVGVIPYL 117
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 118 PYSKQ-CKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVARNP 196
Cdd:PLN02369 81 GYARAdRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVVSPDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 197 GVAKKANSYAERLR-LGLAVihgeqketdadeVDGRysppptrnstpqhaptssaRQRTTSVSVgvpehivkvkppLTIV 275
Cdd:PLN02369 161 GGVARARAFAKKLSdAPLAI------------VDKR-------------------RQGHNVAEV------------MNLI 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 276 GDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEIQKlQCHKIK 355
Cdd:PLN02369 198 GDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATHAVFSPPAIERLSSGLFQEVIVTNTIPVSEKN-YFPQLT 276
|
330 340
....*....|....*....|....*.
gi 24651454 356 TIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:PLN02369 277 VLSVANLLGETIWRVHDDCSVSSIFD 302
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
25-380 |
8.05e-69 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 219.66 E-value: 8.05e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 25 STSDIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKT 104
Cdd:PRK02269 2 SYSDLKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 105 SSARSIVGVIPYLPYSKQ-CKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESI 183
Cdd:PRK02269 82 ASAESINVVMPYYGYARQdRKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 184 PDYRNSVIVARNPGVAKKANSYAERLRLGLAVIhgeqketdadevDGRYspPPTRNSTPQhaptssarqrttsvsvgvpe 263
Cdd:PRK02269 162 LVGDDVVVVSPDHGGVTRARKLAQFLKTPIAII------------DKRR--SVDKMNTSE-------------------- 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 264 hivkvkpPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIP 343
Cdd:PRK02269 208 -------VMNIIGNVKGKKCILIDDMIDTAGTICHAADALAEAGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIY 280
|
330 340 350
....*....|....*....|....*....|....*..
gi 24651454 344 HEIQKLqCHKIKTIDISILIAEAIRRIHNKESMSYLF 380
Cdd:PRK02269 281 LPEERL-IDKIEQISIADLLGEAIIRIHEKRPLSPLF 316
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
35-381 |
3.03e-67 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 215.76 E-value: 3.03e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 35 NSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSARSIVGVI 114
Cdd:PRK02458 16 NSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMIDACKRASANTVNVVL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 115 PYLPYSKQCKMRK-RGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVA 193
Cdd:PRK02458 96 PYFGYARQDRIAKpREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKGLSGSDVVVVS 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 194 -RNPGVaKKANSYAERLRLGLAVIHGEQKETDADEvdgRYsppptrnstpqhaptssarqrttsvsvgvpehivkvkppl 272
Cdd:PRK02458 176 pKNSGI-KRARSLAEYLDAPIAIIDYAQDDSEREE---GY---------------------------------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 273 tIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEIQKLQch 352
Cdd:PRK02458 212 -IIGDVAGKKAILIDDILNTGKTFAEAAKIVEREGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSVATKERVPK-- 288
|
330 340
....*....|....*....|....*....
gi 24651454 353 KIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:PRK02458 289 NVTYLSASELIADAIIRIHERKPLSPLFA 317
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
28-380 |
1.24e-62 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 207.03 E-value: 1.24e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 28 DIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSA 107
Cdd:PTZ00145 119 NAILFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRASA 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 108 RSIVGVIPYLPYSKQ-CKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFD--IPVDNLRASPFLLQYIQESip 184
Cdd:PTZ00145 199 KKITAVIPYYGYARQdRKLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLIGLDYFTKK-- 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 185 DYRNSVIVARNPGVAKKANSYAERL------RLGLAVIhgeqketdadevdgrysppptrnstpqhaptssARQRTTsvs 258
Cdd:PTZ00145 277 DLYKPVIVSPDAGGVYRARKFQDGLnhrgisDCGIAML---------------------------------IKQRTK--- 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 259 vgvPEHIVKvkppLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVV 338
Cdd:PTZ00145 321 ---PNEIEK----MDLVGNVYDSDVIIVDDMIDTSGTLCEAAKQLKKHGARRVFAFATHGLFSGPAIERIEASPLEEVVV 393
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 24651454 339 TNTIPHEIQKLQCHKIKTIDISILIAEAIRRIHNKESMSYLF 380
Cdd:PTZ00145 394 TDTVKSNKNIDSCKKITKLSVSVLVADAIRRIHQKESLNDLF 435
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
31-381 |
1.67e-61 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 201.12 E-value: 1.67e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 31 IINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSARSI 110
Cdd:PRK02812 24 LFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRASARQI 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 111 VGVIPYLPYSK-QCKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQESipDYRNS 189
Cdd:PRK02812 104 TAVIPYYGYARaDRKTAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASK--NLEDI 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 190 VIVARNPGVAKKANSYAERLRLG-LAVIhgeqketdadevDGRysppptrnstpqhaptssaRQRTTSVSVgvpehivkv 268
Cdd:PRK02812 182 VVVSPDVGGVARARAFAKKLNDApLAII------------DKR-------------------RQAHNVAEV--------- 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 269 kppLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEiQK 348
Cdd:PRK02812 222 ---LNVIGDVKGKTAILVDDMIDTGGTICEGARLLRKEGAKQVYACATHAVFSPPAIERLSSGLFEEVIVTNTIPVP-EE 297
|
330 340 350
....*....|....*....|....*....|...
gi 24651454 349 LQCHKIKTIDISILIAEAIRRIHNKESMSYLFR 381
Cdd:PRK02812 298 RRFPQLKVLSVANMLGEAIWRIHEESSVSSMFR 330
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
23-380 |
4.39e-51 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 173.95 E-value: 4.39e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 23 NTSTSDIVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYAC 102
Cdd:PRK00553 4 SIDKSNHVIFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDAL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 103 KTSSARSIVGVIPYLPYSKQ-CKMRKRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQE 181
Cdd:PRK00553 84 KRGSAKSITAILPYYGYARQdRKTAGREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLSRVLE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 182 SIpDYRNSVIVARNPGVAKKANSYAERLRLGLAVIhgeqketdadevDGRysppptrnsTPQHaptssarqrttsvsvGV 261
Cdd:PRK00553 164 LL-GKKDLVVVSPDYGGVKRARLIAESLELPLAII------------DKR---------RPKH---------------NV 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 262 PEHIvkvkpplTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDES----PIDEIV 337
Cdd:PRK00553 207 AESI-------NVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQKAKKVCVMATHGLFNKNAIQLFDEAfkkkLIDKLF 279
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 24651454 338 VTNTIPHEIQKlQCHKIKTIDISILIAEAIRRIHNKESMSYLF 380
Cdd:PRK00553 280 VSNSIPQTKFE-KKPQFKVVDLAHLYEEVLLCYANGGSISAIY 321
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
29-144 |
3.87e-50 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 164.13 E-value: 3.87e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 29 IVIINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIMELLIMAYACKTSSAR 108
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 24651454 109 SIVGVIPYLPYSKQCKM-RKRGCIVSKLLAKMMCTSG 144
Cdd:pfam13793 81 RITAVIPYFGYARQDRKdKPREPITAKLVADLLEAAG 117
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
31-369 |
2.39e-42 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 149.68 E-value: 2.39e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 31 IINGNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTgTKDANNNIMELLIMAYACKTSSARSI 110
Cdd:PRK00934 2 IIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIIST-TYPQDENLVELLLLIDALRDEGAKSI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 111 VGVIPYLPYSKQCKMRKRG-CIVSKLLAKMMCTSGlTHIITMDLHQKEIQGFFDIPVDNLRASPFLLQYIQEsipDYRNS 189
Cdd:PRK00934 81 TLVIPYLGYARQDKRFKPGePISARAIAKIISAYY-DRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGD---KLDDP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 190 VIVARNPGVAKKANSYAErlRLGLAVIHGEQKetdadevdgRYSPpptrnstpqhaptssarqrTTsvsvgvpehiVKVK 269
Cdd:PRK00934 157 LVLAPDKGALELAKEAAE--ILGCEYDYLEKT---------RISP-------------------TE----------VEIA 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 270 PPlTIvgDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEIQKl 349
Cdd:PRK00934 197 PK-NL--DVKGKDVLIVDDIISTGGTMATAIKILKEQGAKKVYVACVHPVLVGDAILKLYNAGVDEIIVTDTLESEVSK- 272
|
330 340
....*....|....*....|
gi 24651454 350 qchkiktIDISILIAEAIRR 369
Cdd:PRK00934 273 -------ISVAPLIADLLKK 285
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
61-382 |
4.32e-30 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 118.90 E-value: 4.32e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 61 SNRETIVEISDSVRGKDIYIIQ--------------TGTKDANNNIMELLIMAYACKtSSARSIVGVIPYLPYSKQCKMR 126
Cdd:PRK06827 63 SNGEAKGEILESVRGKDIYILQdvgnysvtynmfgeKNHMSPDDHFQDLKRTIDAIR-GKARRITVIMPFLYESRQHKRK 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 127 KRGCIVSKLLAKMMCTSGLTHIITMDLHQKEIQGFFDIP-VDNLRASPFLLQYIQESIPDYR----NSVIVARNPGVAKK 201
Cdd:PRK06827 142 GRESLDCALALQELEELGVDNIITFDAHDPRIENAIPLMgFENLYPSYQIIKALLKNEKDLEidkdHLMVISPDTGAMDR 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 202 ANSYAERLRLGLAVIHgeqKETDadevdgrYSppptrnstpqhaptssarqrttsvsvgvpeHIVKVKPPLT----IVGD 277
Cdd:PRK06827 222 AKYYASVLGVDLGLFY---KRRD-------YS------------------------------RVVNGRNPIVahefLGRD 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 278 VSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLsSDAPRQLDES----PIDEIVVTNTIPHEIQKLQCHK 353
Cdd:PRK06827 262 VEGKDVLIVDDMIASGGSMIDAAKELKSRGAKKIIVAATFGFF-TNGLEKFDKAyeegYFDRIIGTNLVYHPEELLSKPW 340
|
330 340
....*....|....*....|....*....
gi 24651454 354 IKTIDISILIAEAIRRIHNKESMSYLFRN 382
Cdd:PRK06827 341 YIEVDMSKLIARIIDALNHDVSLSKLLDP 369
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
39-369 |
5.43e-17 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 80.75 E-value: 5.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 39 DLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTgTKDANNNIMELLIMAYACKTSSARSIVGVIPYLP 118
Cdd:PRK07199 13 AAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCS-LDRPDEKLLPLLFAAEAARELGARRVGLVAPYLA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 119 YSKQCKMRKRGCIVS-KLLAKMMCTSgLTHIITMD--LHQ-KEIQGFFDIPVDNLRASPFLLQYIQESIPDyrnsvivar 194
Cdd:PRK07199 92 YMRQDIAFHPGEAISqRHFARLLSGS-FDRLVTVDphLHRyPSLSEVYPIPAVVLSAAPAIAAWIRAHVPR--------- 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 195 npgvakkansyaerlrlglAVIHGEQKETD--ADEVDGRYSPPptrnstpqHAPTSSARQRTTSVSVGVPEhivkvkppl 272
Cdd:PRK07199 162 -------------------PLLIGPDEESEqwVAAVAERAGAP--------HAVLRKTRHGDRDVEISLPD--------- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 273 tiVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAPRQLDESPIDEIVVTNTIPHEIQklqch 352
Cdd:PRK07199 206 --AAPWAGRTPVLVDDIVSTGRTLIEAARQLRAAGAASPDCVVVHALFAGDAYSALAAAGIARVVSTDTVPHPSN----- 278
|
330
....*....|....*..
gi 24651454 353 kikTIDISILIAEAIRR 369
Cdd:PRK07199 279 ---AISLAPLLAEALRR 292
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
171-341 |
5.65e-12 |
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Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 62.41 E-value: 5.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 171 ASPFLLQYIQESIPDyrNSVIVARNPGVAKKANSYAERLRLGLAVIHGEqketdadevdgRYSPPPTRnstpqhaptssa 250
Cdd:cd06223 1 AGRLLAEEIREDLLE--PDVVVGILRGGLPLAAALARALGLPLAFIRKE-----------RKGPGRTP------------ 55
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24651454 251 rqrttsvsvgvpehIVKVKPPLTIVGDVSGRIAIMVDDLIDDVQAFVAAAEMLKENGACKIYVLATHGLLSSDAprQLDE 330
Cdd:cd06223 56 --------------SEPYGLELPLGGDVKGKRVLLVDDVIATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELA 119
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170
....*....|.
gi 24651454 331 SPIDEIVVTNT 341
Cdd:cd06223 120 SPGDPVYSLFT 130
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