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Conserved domains on  [gi|42572861|ref|NP_974527|]
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SNARE-like superfamily protein [Arabidopsis thaliana]

Protein Classification

longin-like domain-containing protein( domain architecture ID 1000061)

longin-like domain-containing protein; longin-like domains are small protein domains present in a variety of proteins and members of protein complexes involved in or required for different steps during the transport of proteins from the ribosome to the ER to the plasma membrane, via the Golgi apparatus

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
longin-like super family cl38905
Longin-like domains; Longin-like domains are small protein domains present in a variety of ...
 10-93 1.45e-06

Longin-like domains; Longin-like domains are small protein domains present in a variety of proteins and members of protein complexes involved in or required for different steps during the transport of proteins from the ribosome to the ER to the plasma membrane, via the Golgi apparatus. Examples are mu and sigma subunits of the heterotetrameric adaptor protein (AP) complex, zeta and delta subunits of the heterotetrameric F-COPI complex, a subgroup of R-SNARE proteins, a subfamily of the transport protein particle (TRAPP), and the signal recognition particle receptor subunit alpha (SR-alpha).


The actual alignment was detected with superfamily member cd14824:

Pssm-ID: 365781  Cd Length: 122  Bit Score: 46.09  E-value: 1.45e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572861  10 YCCVSR--DNQIL-----YSYNGGDQTN-ESLAALCLEKSPPF--HTWYFEtiGKRRFGFLIGDGFVYFAIVDEVLKRSS 79
Cdd:cd14824   2 YALIARgsDGLILaeytdLSSFSSVKENfKFVAKTILERTPPSgqRQSVEE--GDYVFHYLVEDGLCYLCITDKEYPKRV 79

                        90
                ....*....|....
gi 42572861  80 VLKFLEHLRDEFKK 93
Cdd:cd14824  80 AFAFLEEVLDEFLS 93
 
Name Accession Description Interval E-value
Longin cd14824
longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including ...
 10-93 1.45e-06

longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including VAMP7, Ykt6, and Sec22. Longin is one of the approximately 26 components required for transporting proteins from the ER to the plasma membrane, via the Golgi apparatus. It is necessary for the steps of the transfer from the ER to the Golgi complex. Longins are the only R-SNAREs that are common to all eukaryotes, and they are characterized by a conserved N-terminal domain with a profilin-like fold called a longin domain.


Pssm-ID: 341428  Cd Length: 122  Bit Score: 46.09  E-value: 1.45e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572861  10 YCCVSR--DNQIL-----YSYNGGDQTN-ESLAALCLEKSPPF--HTWYFEtiGKRRFGFLIGDGFVYFAIVDEVLKRSS 79
Cdd:cd14824   2 YALIARgsDGLILaeytdLSSFSSVKENfKFVAKTILERTPPSgqRQSVEE--GDYVFHYLVEDGLCYLCITDKEYPKRV 79

                        90
                ....*....|....
gi 42572861  80 VLKFLEHLRDEFKK 93
Cdd:cd14824  80 AFAFLEEVLDEFLS 93
 
Name Accession Description Interval E-value
Longin cd14824
longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including ...
 10-93 1.45e-06

longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including VAMP7, Ykt6, and Sec22. Longin is one of the approximately 26 components required for transporting proteins from the ER to the plasma membrane, via the Golgi apparatus. It is necessary for the steps of the transfer from the ER to the Golgi complex. Longins are the only R-SNAREs that are common to all eukaryotes, and they are characterized by a conserved N-terminal domain with a profilin-like fold called a longin domain.


Pssm-ID: 341428  Cd Length: 122  Bit Score: 46.09  E-value: 1.45e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572861  10 YCCVSR--DNQIL-----YSYNGGDQTN-ESLAALCLEKSPPF--HTWYFEtiGKRRFGFLIGDGFVYFAIVDEVLKRSS 79
Cdd:cd14824   2 YALIARgsDGLILaeytdLSSFSSVKENfKFVAKTILERTPPSgqRQSVEE--GDYVFHYLVEDGLCYLCITDKEYPKRV 79

                        90
                ....*....|....
gi 42572861  80 VLKFLEHLRDEFKK 93
Cdd:cd14824  80 AFAFLEEVLDEFLS 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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