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Concise Results
Standard Results
Full Results
RecName: Full=Glutathione hydrolase proenzyme 2; AltName: Full=Gamma-glutamyltransferase 2; AltName: Full=Gamma-glutamyltranspeptidase 2; Contains: RecName: Full=Glutathione hydrolase 2 heavy chain; Contains: RecName: Full=Glutathione hydrolase 2 light chain; Flags: Precursor
Protein Classification
gamma-glutamyltransferase family protein ( domain architecture ID 10470232 )
gamma-glutamyltransferase family protein exhibits gamma-glutamyltranspeptidase and/or cephalosporin acylase and/or glutathione hydrolase activity, all involving the hydrolytic splitting of a peptide-like C-N bond
List of domain hits
Name
Accession
Description
Interval
E-value
G_glu_transpept
pfam01019 Gamma-glutamyltranspeptidase;
96-606
0e+00
Gamma-glutamyltranspeptidase;
Pssm-ID: 425991
Cd Length: 499
Bit Score: 605.74
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 96 VSM L AD GGNAVDAA I A STF C I GVV NFF SSGIGGGGFMLI KHPNETA - QSLTF RE I AP GNVS K H MFD K -- NPM L AQV G P L S 172
Cdd:pfam01019 1 LDI L RK GGNAVDAA V A AAL C L GVV EPH SSGIGGGGFMLI YDAKTGK v LVIDA RE T AP AAAT K D MFD G kg DSK L SLT G G L A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 173 IAI PGE L AGL Y EA W K SH G L L D W SK LLEP NV KLAR E GFPV TR A ME R V L KLP E m AH L LK DP IWQP I LM P N G K VL R AG DKMFR 252
Cdd:pfam01019 81 VGV PGE V AGL A EA H K RY G R L P W AD LLEP AI KLAR D GFPV SP A LA R A L ARA E - ER L RA DP GLRK I FL P T G R VL K AG ELLKQ 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 253 PA Y AKTLE I IA NK G IEP FYRGEL TNSM V KFI Q D NGGI V T V ED FG NY STVFADA L HTS Y R G HD VY TCTLPTS G P AL IEG LN 332
Cdd:pfam01019 160 PA L AKTLE L IA EE G PDA FYRGEL AQQL V ADL Q A NGGI I T A ED LA NY RVKIREP L SAD Y G G YT VY SPPPSSG G I AL LQI LN 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 333 IL D G YP L NTP s L AFPKR LHL EV EAMK WLS A G RT QF - GDPDF L P ldhl DV V SK LLS K E F A SQIRNN I SLSKTY P WEHY nps 411
Cdd:pfam01019 240 IL E G FD L SSL - L NSAEY LHL LI EAMK LAY A D RT RY l GDPDF V P ---- VP V EN LLS P E Y A KERAKL I NPNAAF P SSYA --- 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 412 ydl P ISH GTTH V S T VD SNNL AVS I TST V NL L FGS QLMD P V TG VVF N DQ MDDFS I P GA s NAF N L S PSP W N F I E P F KRP Q SS 491
Cdd:pfam01019 312 --- P EDG GTTH F S V VD RDGN AVS F TST I NL G FGS GVVV P G TG ILL N NE MDDFS T P PG - NAF G L D PSP A N A I A P G KRP L SS 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 492 S APTI LT D i N G DFEMAL GA S GGSRI VT AVL DS I IKRI D MDY D IESM V ASA R P HHQ l LPD I L IL E S GF SKS V ATRMKKY GH 571
Cdd:pfam01019 388 M APTI VL D - D G KPVLVV GA P GGSRI IS AVL QV I VNVL D LGL D LQQA V DAP R I HHQ - LPD V L EV E P GF PEE V LAELEAR GH 465
490 500 510
....*....|....*....|....*....|....*
gi 74581982 572 KV WRLKQH d TPLSQ IQ A V T R HHSEY Y GM SDPR KY G 606
Cdd:pfam01019 466 KV KVVEDS - SSVGA IQ I V R R TGGVL Y AA SDPR RD G 499
Name
Accession
Description
Interval
E-value
G_glu_transpept
pfam01019 Gamma-glutamyltranspeptidase;
96-606
0e+00
Gamma-glutamyltranspeptidase;
Pssm-ID: 425991
Cd Length: 499
Bit Score: 605.74
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 96 VSM L AD GGNAVDAA I A STF C I GVV NFF SSGIGGGGFMLI KHPNETA - QSLTF RE I AP GNVS K H MFD K -- NPM L AQV G P L S 172
Cdd:pfam01019 1 LDI L RK GGNAVDAA V A AAL C L GVV EPH SSGIGGGGFMLI YDAKTGK v LVIDA RE T AP AAAT K D MFD G kg DSK L SLT G G L A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 173 IAI PGE L AGL Y EA W K SH G L L D W SK LLEP NV KLAR E GFPV TR A ME R V L KLP E m AH L LK DP IWQP I LM P N G K VL R AG DKMFR 252
Cdd:pfam01019 81 VGV PGE V AGL A EA H K RY G R L P W AD LLEP AI KLAR D GFPV SP A LA R A L ARA E - ER L RA DP GLRK I FL P T G R VL K AG ELLKQ 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 253 PA Y AKTLE I IA NK G IEP FYRGEL TNSM V KFI Q D NGGI V T V ED FG NY STVFADA L HTS Y R G HD VY TCTLPTS G P AL IEG LN 332
Cdd:pfam01019 160 PA L AKTLE L IA EE G PDA FYRGEL AQQL V ADL Q A NGGI I T A ED LA NY RVKIREP L SAD Y G G YT VY SPPPSSG G I AL LQI LN 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 333 IL D G YP L NTP s L AFPKR LHL EV EAMK WLS A G RT QF - GDPDF L P ldhl DV V SK LLS K E F A SQIRNN I SLSKTY P WEHY nps 411
Cdd:pfam01019 240 IL E G FD L SSL - L NSAEY LHL LI EAMK LAY A D RT RY l GDPDF V P ---- VP V EN LLS P E Y A KERAKL I NPNAAF P SSYA --- 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 412 ydl P ISH GTTH V S T VD SNNL AVS I TST V NL L FGS QLMD P V TG VVF N DQ MDDFS I P GA s NAF N L S PSP W N F I E P F KRP Q SS 491
Cdd:pfam01019 312 --- P EDG GTTH F S V VD RDGN AVS F TST I NL G FGS GVVV P G TG ILL N NE MDDFS T P PG - NAF G L D PSP A N A I A P G KRP L SS 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 492 S APTI LT D i N G DFEMAL GA S GGSRI VT AVL DS I IKRI D MDY D IESM V ASA R P HHQ l LPD I L IL E S GF SKS V ATRMKKY GH 571
Cdd:pfam01019 388 M APTI VL D - D G KPVLVV GA P GGSRI IS AVL QV I VNVL D LGL D LQQA V DAP R I HHQ - LPD V L EV E P GF PEE V LAELEAR GH 465
490 500 510
....*....|....*....|....*....|....*
gi 74581982 572 KV WRLKQH d TPLSQ IQ A V T R HHSEY Y GM SDPR KY G 606
Cdd:pfam01019 466 KV KVVEDS - SSVGA IQ I V R R TGGVL Y AA SDPR RD G 499
Ggt
COG0405 Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
83-604
3.72e-144
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
Pssm-ID: 440174
Cd Length: 507
Bit Score: 427.16
E-value: 3.72e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 83 A VA SEV P VC S DI G VSM L AD GGNAVDAA I A STFCIG VV nffssgiggggf M LI KH - PNETAQS L TF R EI AP GNVSKH M F - D 160
Cdd:COG0405 1 M VA TAH P LA S QA G LEI L RA GGNAVDAA V A AAAALA VV ephssgiggggf A LI YD a KDGKVTA L DG R GT AP AAATPD M Y l D 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 161 KNPMLAQV GPL SIAI PG EL AG LYE A WKSH G L L DWSK LL E P NVK LA RE GFPV TRAMERV L KL p EMAH L LK DP IWQP I LM P N 240
Cdd:COG0405 81 AGDEIPVR GPL AVGV PG TV AG WEA A HERY G T L PLAE LL A P AIR LA ED GFPV SPRLAAL L AA - AAER L AR DP GAAA I FL P D 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 241 G KVLR AGD KMFR P AY A K TL EI IA NK G IEP FYRGE LTNSM V KFI Q DN GG IV T V ED FGN Y STVFADA L HTS YRG HD VY TCTL 320
Cdd:COG0405 160 G RPPK AGD ILRQ P DL A A TL RR IA EE G ADA FYRGE IAEAI V AAV Q AA GG LL T L ED LAA Y RAEWREP L SGT YRG YT VY SMPP 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 321 P TS G P AL IEG LNIL D G YP L nt PS L AF -- PKRL HL EV EAMK WLS A G R TQF - GDPDF LPLD hldv V SK LLS KEF A SQIRNN I 397
Cdd:COG0405 240 P SQ G I AL LQI LNIL E G FD L -- AA L GP ds AEYV HL LA EAMK LAF A D R DRY l GDPDF VDVP ---- V EG LLS PAY A AERAAL I 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 398 SLSKTY P WEHYNPSYDLP i S HG TTH V S T VD SNNL AVS I T STVNLL FGS QLMD P V TG VVF N DQM DDFS ipgasnafn L S P S 477
Cdd:COG0405 314 DPDRAT P SPRPGDPTGPE - S GD TTH L S V VD RDGN AVS L T QSIYGG FGS GVVV P G TG FLL N NRG DDFS --------- L D P G 383
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 478 PW N FIE P F KRP Q S SSA PTI LTD i N G DFEMAL G AS GGSRI VTA VL DSIIKRI D MDYDIESM V ASA R P HHQ L LPD I L I LE SG 557
Cdd:COG0405 384 HP N ALA P G KRP R S TMS PTI VLK - D G KPVLVF G SP GGSRI PQT VL QVLLNVL D FGMNPQEA V DAP R W HHQ G LPD T L E LE PR 462
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 74581982 558 F SKS V ATRMKKY GHKV wrl KQHDTPLSQI QA VT R HHS - EYY G MS DPR K 604
Cdd:COG0405 463 F PPA V IAALRAR GHKV --- EVVPDWSGGA QA IL R DPD g VLE G AA DPR R 507
g_glut_trans
TIGR00066 gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
82-603
4.06e-132
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]
Pssm-ID: 129176
Cd Length: 516
Bit Score: 396.83
E-value: 4.06e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 82 G A VAS EVPVC S D IG VSM L AD GGNA V DAA I A STFCIG VV NF F SS G I GGGGFMLI KHP - NETAQSLT FRE I AP GNVSKH MF - 159
Cdd:TIGR00066 1 G M VAS LHALA S E IG EDI L KE GGNA F DAA V A VGLALA VV EP F MT G L GGGGFMLI SGK k TKDTTAID FRE R AP AKATRD MF l 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 160 DK N ---- P MLAQV G P L S I AI PG EL AGL YE A W K SH G L L DWSK L L EP NV KLAR E GFP VTR A MERV L K L P E MAH L LKDPIWQP 235
Cdd:TIGR00066 81 DK S gnpl P GKSLT G G L A I GV PG TV AGL EA A L K KY G T L PLKD L I EP AI KLAR N GFP INE A LADT L E L Y E EVL L TTKEDSKD 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 236 I LM P N GK V L RA GD KMFRPAY AK T LE I IA NK G IEP FY R G ELTN S MVKFI Q D NGGI V T VE D FGN Y STVFADA L HTS YRG HD V 315
Cdd:TIGR00066 161 I FN P T GK P L KE GD TLVQKDL AK S LE L IA EN G PDA FY K G DIAE S IIDTL Q K NGGI M T KK D LAA Y DVEIRKP L SGD YRG YQ V 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 316 YT CTL P T S - G PA L IEG LNIL DGYP L NTPSLAFPKRLH L EV EAMK WLS A G R TQF - GDP D F LPL d H L D vvs K LL S K EF A SQI 393
Cdd:TIGR00066 241 YT TPP P S S g G IH L LQA LNIL ENFD L SQYGDGSAETYQ L LA EAMK LSY A D R SRY l GDP E F VDV - P L E --- E LL D K RY A KEL 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 394 RNN I SLS K TY P - WEH Y NPS Y DLPISHG TTH V S T VD SNNL AVS I T S T V NL L FGS QLMD P V TG VVF N DQ MDDFS ipgasnaf 472
Cdd:TIGR00066 317 AQS I KIN K VD P k STI Y PGA Y QPNEGSQ TTH F S V VD RDGN AVS L T T T I NL E FGS GVHA P D TG ILL N NE MDDFS -------- 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 473 n L S P SPW N FI EP F KRP Q SS S APTI LTD i N G DFEMAL G AS GGSRI V T A VL DS I IKR ID MDYDIESM V ASA R P HHQ L LPD I L 552
Cdd:TIGR00066 389 - L K P GGA N AV EP N KRP L SS M APTI VLK - D G KPDLVV G SP GGSRI I T T VL QT I VRH ID YGMPLAEA V SEP R I HHQ W LPD E L 466
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 74581982 553 I LE S GF SKS V ATRM K KY GHKV w R LK Q h DT P LSQI QA V - TRHHSEY YG M SDPR 603
Cdd:TIGR00066 467 R LE K GF PDD V LQLL K DM GHKV - T LK E - VF P MGVV QA I r VDPEGWL YG V SDPR 516
PLN02198
PLN02198 glutathione gamma-glutamylcysteinyltransferase
53-611
5.10e-110
glutathione gamma-glutamylcysteinyltransferase
Pssm-ID: 177849
Cd Length: 573
Bit Score: 341.67
E-value: 5.10e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 53 MT LF VLVYSISSN lhtp T Q FTGHKVRGRR GAVA SEVPV CS D IG VSM L AD GGNA V DA AI A STF C I GVV NFF SSGIGGG G F M 132
Cdd:PLN02198 9 IV LF IIAFLQNAA ---- A Q KRQQSIVASH GAVA TDDGR CS V IG MNV L RE GGNA I DA SV A AAL C L GVV SPA SSGIGGG A F T 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 133 LIK HP N ETAQSLTF RE I AP GNVSKH M FDK N PM L AQV G P LS IAI PGE L AGL YE AWK S HG L L D W SK L LE P NV KLA R EGF PVT 212
Cdd:PLN02198 85 LIK LA N GEEIAYDS RE T AP LSATEN M YGG N VE L KKK G A LS VGV PGE V AGL FT AWK Q HG K L P W KR L VR P AE KLA A EGF KIS 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 213 RAMERVLKLPE m AHL L K D PIWQPILMP NG KVLRA G DKMFR P AY A K TL EI I ANK G IEP FY R G ELTNSM V KF IQ DN GGI V T V 292
Cdd:PLN02198 165 KYLYMQMNATR - SDI L A D KGLSDLFVS NG ELKKP G TICHN P KL A L TL RL I GEY G PKA FY N G TVGVNL V RD IQ KS GGI I T L 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 293 E D FGN Y STVFADA L HTSYR G HD V YTCTL P T S - G P A LIEG LNIL DG Y PL nt PS - LAF P KRL H LEV EA M K WLS A G R TQF GDP 370
Cdd:PLN02198 244 K D LQS Y RVKVKEP L SADIL G YR V LGMPP P S S g G A A MMLI LNIL AQ Y GI -- PS g VSG P LGV H RLI EA L K HAF A V R MNL GDP 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 371 DF lp L D HLD VVS KL LS KE FA SQIRNN I SLS KT YPWE HY NPSYDLPIS HGT T H V S TV DS NNL AVS I TST V N LL FG SQLMD P 450
Cdd:PLN02198 322 DF -- V D VTK VVS DM LS PK FA QDLKSK I NDN KT FDPK HY GGRWNQIDD HGT S H L S II DS ERN AVS M TST I N GY FG ALMLS P 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 451 V TG V V F N DQ MDDFSIP GA S NAFN -- LS P S P W NFI E P F KRP Q SS SA PTI LTD i N G DFEM A L GASGG SR I VTAVLDSIIKRI 528
Cdd:PLN02198 400 S TG I V L N NE MDDFSIP MK S GGNL dv PP P A P A NFI R P G KRP L SS MT PTI VLK - D G KVKA A V GASGG AN I IAGTTEVYLNHF 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 529 DMDY D IE S M V ASA R PH HQL L P DILIL E S --------- GFS K SVATRMK K Y GH KVWRLKQHDTPLSQI Q AVTRHH --- SE Y 596
Cdd:PLN02198 479 FLKM D PL S S V LAP R IY HQL I P NRASY E N wttvyndhf EIP K ATRVVLE K K GH VLSPIAGGTIAQFIV Q ESGENS ggr SE L 558
570
....*....|....*
gi 74581982 597 YGM SDPRK Y G QAAA Y 611
Cdd:PLN02198 559 VAV SDPRK G G FPSG Y 573
Name
Accession
Description
Interval
E-value
G_glu_transpept
pfam01019 Gamma-glutamyltranspeptidase;
96-606
0e+00
Gamma-glutamyltranspeptidase;
Pssm-ID: 425991
Cd Length: 499
Bit Score: 605.74
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 96 VSM L AD GGNAVDAA I A STF C I GVV NFF SSGIGGGGFMLI KHPNETA - QSLTF RE I AP GNVS K H MFD K -- NPM L AQV G P L S 172
Cdd:pfam01019 1 LDI L RK GGNAVDAA V A AAL C L GVV EPH SSGIGGGGFMLI YDAKTGK v LVIDA RE T AP AAAT K D MFD G kg DSK L SLT G G L A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 173 IAI PGE L AGL Y EA W K SH G L L D W SK LLEP NV KLAR E GFPV TR A ME R V L KLP E m AH L LK DP IWQP I LM P N G K VL R AG DKMFR 252
Cdd:pfam01019 81 VGV PGE V AGL A EA H K RY G R L P W AD LLEP AI KLAR D GFPV SP A LA R A L ARA E - ER L RA DP GLRK I FL P T G R VL K AG ELLKQ 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 253 PA Y AKTLE I IA NK G IEP FYRGEL TNSM V KFI Q D NGGI V T V ED FG NY STVFADA L HTS Y R G HD VY TCTLPTS G P AL IEG LN 332
Cdd:pfam01019 160 PA L AKTLE L IA EE G PDA FYRGEL AQQL V ADL Q A NGGI I T A ED LA NY RVKIREP L SAD Y G G YT VY SPPPSSG G I AL LQI LN 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 333 IL D G YP L NTP s L AFPKR LHL EV EAMK WLS A G RT QF - GDPDF L P ldhl DV V SK LLS K E F A SQIRNN I SLSKTY P WEHY nps 411
Cdd:pfam01019 240 IL E G FD L SSL - L NSAEY LHL LI EAMK LAY A D RT RY l GDPDF V P ---- VP V EN LLS P E Y A KERAKL I NPNAAF P SSYA --- 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 412 ydl P ISH GTTH V S T VD SNNL AVS I TST V NL L FGS QLMD P V TG VVF N DQ MDDFS I P GA s NAF N L S PSP W N F I E P F KRP Q SS 491
Cdd:pfam01019 312 --- P EDG GTTH F S V VD RDGN AVS F TST I NL G FGS GVVV P G TG ILL N NE MDDFS T P PG - NAF G L D PSP A N A I A P G KRP L SS 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 492 S APTI LT D i N G DFEMAL GA S GGSRI VT AVL DS I IKRI D MDY D IESM V ASA R P HHQ l LPD I L IL E S GF SKS V ATRMKKY GH 571
Cdd:pfam01019 388 M APTI VL D - D G KPVLVV GA P GGSRI IS AVL QV I VNVL D LGL D LQQA V DAP R I HHQ - LPD V L EV E P GF PEE V LAELEAR GH 465
490 500 510
....*....|....*....|....*....|....*
gi 74581982 572 KV WRLKQH d TPLSQ IQ A V T R HHSEY Y GM SDPR KY G 606
Cdd:pfam01019 466 KV KVVEDS - SSVGA IQ I V R R TGGVL Y AA SDPR RD G 499
Ggt
COG0405 Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
83-604
3.72e-144
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
Pssm-ID: 440174
Cd Length: 507
Bit Score: 427.16
E-value: 3.72e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 83 A VA SEV P VC S DI G VSM L AD GGNAVDAA I A STFCIG VV nffssgiggggf M LI KH - PNETAQS L TF R EI AP GNVSKH M F - D 160
Cdd:COG0405 1 M VA TAH P LA S QA G LEI L RA GGNAVDAA V A AAAALA VV ephssgiggggf A LI YD a KDGKVTA L DG R GT AP AAATPD M Y l D 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 161 KNPMLAQV GPL SIAI PG EL AG LYE A WKSH G L L DWSK LL E P NVK LA RE GFPV TRAMERV L KL p EMAH L LK DP IWQP I LM P N 240
Cdd:COG0405 81 AGDEIPVR GPL AVGV PG TV AG WEA A HERY G T L PLAE LL A P AIR LA ED GFPV SPRLAAL L AA - AAER L AR DP GAAA I FL P D 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 241 G KVLR AGD KMFR P AY A K TL EI IA NK G IEP FYRGE LTNSM V KFI Q DN GG IV T V ED FGN Y STVFADA L HTS YRG HD VY TCTL 320
Cdd:COG0405 160 G RPPK AGD ILRQ P DL A A TL RR IA EE G ADA FYRGE IAEAI V AAV Q AA GG LL T L ED LAA Y RAEWREP L SGT YRG YT VY SMPP 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 321 P TS G P AL IEG LNIL D G YP L nt PS L AF -- PKRL HL EV EAMK WLS A G R TQF - GDPDF LPLD hldv V SK LLS KEF A SQIRNN I 397
Cdd:COG0405 240 P SQ G I AL LQI LNIL E G FD L -- AA L GP ds AEYV HL LA EAMK LAF A D R DRY l GDPDF VDVP ---- V EG LLS PAY A AERAAL I 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 398 SLSKTY P WEHYNPSYDLP i S HG TTH V S T VD SNNL AVS I T STVNLL FGS QLMD P V TG VVF N DQM DDFS ipgasnafn L S P S 477
Cdd:COG0405 314 DPDRAT P SPRPGDPTGPE - S GD TTH L S V VD RDGN AVS L T QSIYGG FGS GVVV P G TG FLL N NRG DDFS --------- L D P G 383
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 478 PW N FIE P F KRP Q S SSA PTI LTD i N G DFEMAL G AS GGSRI VTA VL DSIIKRI D MDYDIESM V ASA R P HHQ L LPD I L I LE SG 557
Cdd:COG0405 384 HP N ALA P G KRP R S TMS PTI VLK - D G KPVLVF G SP GGSRI PQT VL QVLLNVL D FGMNPQEA V DAP R W HHQ G LPD T L E LE PR 462
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 74581982 558 F SKS V ATRMKKY GHKV wrl KQHDTPLSQI QA VT R HHS - EYY G MS DPR K 604
Cdd:COG0405 463 F PPA V IAALRAR GHKV --- EVVPDWSGGA QA IL R DPD g VLE G AA DPR R 507
g_glut_trans
TIGR00066 gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
82-603
4.06e-132
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]
Pssm-ID: 129176
Cd Length: 516
Bit Score: 396.83
E-value: 4.06e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 82 G A VAS EVPVC S D IG VSM L AD GGNA V DAA I A STFCIG VV NF F SS G I GGGGFMLI KHP - NETAQSLT FRE I AP GNVSKH MF - 159
Cdd:TIGR00066 1 G M VAS LHALA S E IG EDI L KE GGNA F DAA V A VGLALA VV EP F MT G L GGGGFMLI SGK k TKDTTAID FRE R AP AKATRD MF l 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 160 DK N ---- P MLAQV G P L S I AI PG EL AGL YE A W K SH G L L DWSK L L EP NV KLAR E GFP VTR A MERV L K L P E MAH L LKDPIWQP 235
Cdd:TIGR00066 81 DK S gnpl P GKSLT G G L A I GV PG TV AGL EA A L K KY G T L PLKD L I EP AI KLAR N GFP INE A LADT L E L Y E EVL L TTKEDSKD 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 236 I LM P N GK V L RA GD KMFRPAY AK T LE I IA NK G IEP FY R G ELTN S MVKFI Q D NGGI V T VE D FGN Y STVFADA L HTS YRG HD V 315
Cdd:TIGR00066 161 I FN P T GK P L KE GD TLVQKDL AK S LE L IA EN G PDA FY K G DIAE S IIDTL Q K NGGI M T KK D LAA Y DVEIRKP L SGD YRG YQ V 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 316 YT CTL P T S - G PA L IEG LNIL DGYP L NTPSLAFPKRLH L EV EAMK WLS A G R TQF - GDP D F LPL d H L D vvs K LL S K EF A SQI 393
Cdd:TIGR00066 241 YT TPP P S S g G IH L LQA LNIL ENFD L SQYGDGSAETYQ L LA EAMK LSY A D R SRY l GDP E F VDV - P L E --- E LL D K RY A KEL 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 394 RNN I SLS K TY P - WEH Y NPS Y DLPISHG TTH V S T VD SNNL AVS I T S T V NL L FGS QLMD P V TG VVF N DQ MDDFS ipgasnaf 472
Cdd:TIGR00066 317 AQS I KIN K VD P k STI Y PGA Y QPNEGSQ TTH F S V VD RDGN AVS L T T T I NL E FGS GVHA P D TG ILL N NE MDDFS -------- 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 473 n L S P SPW N FI EP F KRP Q SS S APTI LTD i N G DFEMAL G AS GGSRI V T A VL DS I IKR ID MDYDIESM V ASA R P HHQ L LPD I L 552
Cdd:TIGR00066 389 - L K P GGA N AV EP N KRP L SS M APTI VLK - D G KPDLVV G SP GGSRI I T T VL QT I VRH ID YGMPLAEA V SEP R I HHQ W LPD E L 466
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 74581982 553 I LE S GF SKS V ATRM K KY GHKV w R LK Q h DT P LSQI QA V - TRHHSEY YG M SDPR 603
Cdd:TIGR00066 467 R LE K GF PDD V LQLL K DM GHKV - T LK E - VF P MGVV QA I r VDPEGWL YG V SDPR 516
PLN02198
PLN02198 glutathione gamma-glutamylcysteinyltransferase
53-611
5.10e-110
glutathione gamma-glutamylcysteinyltransferase
Pssm-ID: 177849
Cd Length: 573
Bit Score: 341.67
E-value: 5.10e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 53 MT LF VLVYSISSN lhtp T Q FTGHKVRGRR GAVA SEVPV CS D IG VSM L AD GGNA V DA AI A STF C I GVV NFF SSGIGGG G F M 132
Cdd:PLN02198 9 IV LF IIAFLQNAA ---- A Q KRQQSIVASH GAVA TDDGR CS V IG MNV L RE GGNA I DA SV A AAL C L GVV SPA SSGIGGG A F T 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 133 LIK HP N ETAQSLTF RE I AP GNVSKH M FDK N PM L AQV G P LS IAI PGE L AGL YE AWK S HG L L D W SK L LE P NV KLA R EGF PVT 212
Cdd:PLN02198 85 LIK LA N GEEIAYDS RE T AP LSATEN M YGG N VE L KKK G A LS VGV PGE V AGL FT AWK Q HG K L P W KR L VR P AE KLA A EGF KIS 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 213 RAMERVLKLPE m AHL L K D PIWQPILMP NG KVLRA G DKMFR P AY A K TL EI I ANK G IEP FY R G ELTNSM V KF IQ DN GGI V T V 292
Cdd:PLN02198 165 KYLYMQMNATR - SDI L A D KGLSDLFVS NG ELKKP G TICHN P KL A L TL RL I GEY G PKA FY N G TVGVNL V RD IQ KS GGI I T L 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 293 E D FGN Y STVFADA L HTSYR G HD V YTCTL P T S - G P A LIEG LNIL DG Y PL nt PS - LAF P KRL H LEV EA M K WLS A G R TQF GDP 370
Cdd:PLN02198 244 K D LQS Y RVKVKEP L SADIL G YR V LGMPP P S S g G A A MMLI LNIL AQ Y GI -- PS g VSG P LGV H RLI EA L K HAF A V R MNL GDP 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 371 DF lp L D HLD VVS KL LS KE FA SQIRNN I SLS KT YPWE HY NPSYDLPIS HGT T H V S TV DS NNL AVS I TST V N LL FG SQLMD P 450
Cdd:PLN02198 322 DF -- V D VTK VVS DM LS PK FA QDLKSK I NDN KT FDPK HY GGRWNQIDD HGT S H L S II DS ERN AVS M TST I N GY FG ALMLS P 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 451 V TG V V F N DQ MDDFSIP GA S NAFN -- LS P S P W NFI E P F KRP Q SS SA PTI LTD i N G DFEM A L GASGG SR I VTAVLDSIIKRI 528
Cdd:PLN02198 400 S TG I V L N NE MDDFSIP MK S GGNL dv PP P A P A NFI R P G KRP L SS MT PTI VLK - D G KVKA A V GASGG AN I IAGTTEVYLNHF 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 529 DMDY D IE S M V ASA R PH HQL L P DILIL E S --------- GFS K SVATRMK K Y GH KVWRLKQHDTPLSQI Q AVTRHH --- SE Y 596
Cdd:PLN02198 479 FLKM D PL S S V LAP R IY HQL I P NRASY E N wttvyndhf EIP K ATRVVLE K K GH VLSPIAGGTIAQFIV Q ESGENS ggr SE L 558
570
....*....|....*
gi 74581982 597 YGM SDPRK Y G QAAA Y 611
Cdd:PLN02198 559 VAV SDPRK G G FPSG Y 573
PLN02180
PLN02180 gamma-glutamyl transpeptidase 4
77-556
1.18e-97
gamma-glutamyl transpeptidase 4
Pssm-ID: 177836
Cd Length: 639
Bit Score: 311.61
E-value: 1.18e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 77 V RGRR G A VA SEVPV CS D IG V S M L AD GG N AVDAA I A S T F CIGVVN FF SSGIGGG G F MLIKHPNET - A QSLTF RE I AP GNV S 155
Cdd:PLN02180 78 V ESEN G V VA ADDAR CS E IG A S V L RR GG H AVDAA V A I T L CIGVVN PM SSGIGGG S F LIVSSQKDS k A EAFDM RE T AP LAA S 157
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 156 K H M FDKNPMLAQV G P LS IAI PGE L AGLYEAWK SH G L L D W SK L L EP NVK LAR E GF P V TRAMERVLK l PEM A HL LKDP IWQP 235
Cdd:PLN02180 158 K D M YKNDASAKSL G A LS MGV PGE I AGLYEAWK RY G R L P W KP L F EP AIE LAR D GF V V HPYLGKAIS - SHA A MI LKDP GLRS 236
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 236 ILMP NG K VL RA G DKMFR P AY A KT LE I I ANK G IEP FY R G ELTNSM VK FIQDN GGI V T VE D FGN Y STVFA DA LHTSYR G HDV 315
Cdd:PLN02180 237 VFSR NG Q VL KP G ETCYN P EL A QS LE T I SEQ G PGA FY N G TIGEKL VK DVKKA GGI I T MD D LRS Y EVLVT DA MSVDVM G YTI 316
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 316 YTCTL P TS G P - ALIEGLN ILD G Y PLNTPSLAFPKR LH LEV EAMK WLS A G R TQF GDP D F LPLD hl DVVSKL LSK EF A SQ I R 394
Cdd:PLN02180 317 HGMPP P SG G T l GFSMVID ILD S Y SNLYTASGRELG LH RLI EAMK HMF A A R MDL GDP E F VNIT -- NAMNQM LSK AH A EE I Q 394
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 395 NN I SLSK T Y P W E H Y NPSYDLPISH GT T H VST VD SNNLA VS I TSTVN LL FG SQLMD P V TG V V F N DQ MDDFS I P GASNAFN L 474
Cdd:PLN02180 395 KR I FDNT T F P P E Y Y LNRWSQLRDQ GT S H FCI VD ADRNS VS M TSTVN YG FG AGVLS P S TG I V L N NE MDDFS T P AEITPDM L 474
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 475 S P S P W NFIEP F KRP Q SS SA P TIL T D i N G D F EM ALG AS GG SR I VT AVL DSIIKRIDMDYDIESM V A SAR PH H Q L L P DILIL 554
Cdd:PLN02180 475 P P A P T NFIEP N KRP L SS MT P LVI T K - D G E F VA ALG GA GG MH I IP AVL QVFLNCFVLNMKPKEA V E SAR IY H R L I P NVVSY 553
..
gi 74581982 555 E S 556
Cdd:PLN02180 554 E N 555
ggt
PRK09615 gamma-glutamyltranspeptidase; Reviewed
75-603
1.62e-93
gamma-glutamyltranspeptidase; Reviewed
Pssm-ID: 181992
Cd Length: 581
Bit Score: 299.13
E-value: 1.62e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 75 H K VR GRR G A VAS EVPVCSDI GV SM L AD GGNAVDAA I A STFCIG V VNFFSSGI GGGGFML IKHP N ETAQSLT FRE I AP GNV 154
Cdd:PRK09615 43 H P VR AKQ G M VAS VDATATQV GV DI L KQ GGNAVDAA V A VGYALA V THPQAGNL GGGGFML LRTK N GNTTAID FRE M AP AKA 122
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 155 SKH MF ----- DKNPMLAQVGP L SIAI PG EL AG LYE A WKSH G LLDWS K LLE P NV KLAR E GF P V TR A MERV LK LPEMAH L LK 229
Cdd:PRK09615 123 TRD MF lddqg NPDSKKSLTSH L ASGT PG TV AG FSL A LDKY G TMPLN K VVQ P AF KLAR D GF I V ND A LADD LK TYGSEV L PN 202
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 230 DPIWQP I LMPN G KV L RA GDK MFRPAY AK T LE I IA NK G IEP FY R G ELTNSMVKFI Q D NGG IV T V ED FGN Y ST V FADALHTS 309
Cdd:PRK09615 203 HENSKA I FWKE G EP L KK GDK LVQANL AK S LE M IA EN G PDA FY K G TIADQIAQEM Q K NGG LI T K ED LAA Y KA V ERTPISGD 282
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 310 YRG HD VY TCTL P T SG PA - LIEG LNIL DGYPLNTPSLAFPKRLHLEV EA M K WLS A G R TQF - GDPDF LPLD hldv VSK L LS K 387
Cdd:PRK09615 283 YRG YQ VY SMPP P S SG GI h IVQI LNIL ENFDMKKYGFGSADAMQIMA EA E K YAY A D R SEY l GDPDF VKVP ---- WQA L TN K 358
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 388 EF A SQ I RNN I SLS K TY P WEHYN P SYDL P I - S HG TTH V S T VD SNNL AV SI T S T V N LL FG SQLMDPVT G VVF N D QMDDFS I - 465
Cdd:PRK09615 359 AY A KS I ADQ I DIN K AK P SSEIR P GKLA P Y e S NQ TTH F S V VD KDGN AV AV T Y T L N TT FG TGIVAGNS G ILL N N QMDDFS A k 438
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74581982 466 PG AS N AFN L SPSPW N FIE P F KRP Q SS SA PTI LTD i N G DFEMAL G AS GGSRI V T A VL DSIIKR ID MDYDIESMVASA R P HH 545
Cdd:PRK09615 439 PG VP N VYG L VGGDA N AVG P N KRP L SS MS PTI VVK - D G KTWLVT G SP GGSRI I T T VL QMVVNS ID YGMNVAEATNAP R F HH 517
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 74581982 546 Q L LPD I L IL E S GFS KSVATRMKKY G H KV wrl KQHDTPL S QIQAVTRHHS E Y YG M SDPR 603
Cdd:PRK09615 518 Q W LPD E L RV E K GFS PDTLKLLEAK G Q KV --- ALKEAMG S TQSIMVGPDG E L YG A SDPR 572
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
