|
Name |
Accession |
Description |
Interval |
E-value |
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
2-233 |
7.61e-121 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 343.25 E-value: 7.61e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 2 LSNFKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARASGADDVLKIASIHDSLSEAIADCQIVLGASA 81
Cdd:COG0565 1 LDNIRVVLVEPQHPGNIGAAARAMKNFGLSDLRLVNPRGWPDEEARAMASGADDVLENARVVDTLEEALADCDLVVGTTA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 82 RDRTISWPSVTARECAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYELFVASG 161
Cdd:COG0565 81 RPRELRKPVLTPREAAEELLARAAGGKVALVFGRERSGLTNEELALCDALVTIPTNPEYPSLNLAQAVQVVAYELRKAAL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1028371151 162 RqyASSIGDRGEESLATAEQMEGFYLHLQQTMADIGFLQPERSKSIMRRLRRVFNRAWLDTKELDILRGILR 233
Cdd:COG0565 161 E--APPLPPPPEPEPATAEELEGLYEHLEELLDAIGFLDPEKPEKLMRRLRRLFGRARLTEREVRTLRGILR 230
|
|
| PRK15114 |
PRK15114 |
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional |
1-232 |
2.43e-86 |
|
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional
Pssm-ID: 185069 Cd Length: 245 Bit Score: 256.22 E-value: 2.43e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 1 MLSNFKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARASGADDVLKIASIHDSLSEAIADCQIVLGAS 80
Cdd:PRK15114 1 MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNATIVDTLDEALAGCSLVVGTS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 81 ARDRTISWPSVTARECAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYELFVAS 160
Cdd:PRK15114 81 ARSRTLPWPMLDPRECGLKSVAEAANAPVALVFGRERVGLTNDELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1028371151 161 -GRQYASSIGDRGEES-LATAEQMEGFYLHLQQTMADIGFLQPERSKSIMRRLRRVFNRAWLDTKELDILRGIL 232
Cdd:PRK15114 161 lATQENGEPQVEHEETpYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTRARPESQELNILRGIL 234
|
|
| rRNA_methyl_1 |
TIGR00050 |
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of ... |
2-233 |
3.68e-81 |
|
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of S-adenosyl-L-methionine (AdoMet)-dependent methyltransferases, and is now characterized, in E. coli, as a tRNA:Cm32/Um32 methyltransferase. It may be named TrMet(Xm32), or TrmJ, according to the nomenclature style chosen [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 272876 [Multi-domain] Cd Length: 233 Bit Score: 242.69 E-value: 3.68e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 2 LSNFKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARASGADDVLKIASIHDSLSEAIADCQIVLGASA 81
Cdd:TIGR00050 1 LENIRIVLVEPSHPGNIGSIARAMKNMGLTELRLVNPRVKLEEEAYALAAGARDILDNAKVVDTLDEALDDCDFVVGTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 82 RDRTISWPSVTARECAEKWVDVAGgaNIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYELFVASG 161
Cdd:TIGR00050 81 RSRNLQRPMLTPRELAPKLVAEKG--KVALVFGREDSGLTNEELQKCHVLVSIPTSEEYPSLNLSHAVAVILYELRMAWL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1028371151 162 RQYASSIgdrgEESLATAEQMEGFYLHLQQTMADIGFLQPERSKSIMRRLRRVFNRAWLDTKELDILRGILR 233
Cdd:TIGR00050 159 AQQENLS----EMPYATVDDLELLLEHLEETLLSLGFIPEHKPRQVMRKFRRLYGRAGLEKRELHILRGILR 226
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
7-156 |
3.25e-72 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 216.98 E-value: 3.25e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 7 VVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHAD-ATARASGADDVLKIASIHDSLSEAIADCQIVLGASARDRT 85
Cdd:cd18093 3 VVLVEPQHPGNIGAVARAMKNFGLSDLRLVNPRCDDPEEaARALASGAEDVLENAKVYDTLEEALADCDLVVATTARPRG 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1028371151 86 ISWPSVTARECAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYEL 156
Cdd:cd18093 83 LRRPLLTPRELAELLKEHAAGGKVALVFGREDSGLTNEELALCDLLVTIPTNPEYPSLNLAQAVAIVLYEL 153
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
4-154 |
1.06e-34 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 121.10 E-value: 1.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 4 NFKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATAR--ASGADDVLKIAsIHDSLSEAIADCQ----IVL 77
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPYNPKAIraSAGALFHLPLV-VVDNLEEALKDLKeagyAVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 78 GASARDR---TISWPSvtarecaekwvdvaggaNIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCY 154
Cdd:pfam00588 80 ATSLGGKslyEIDFPK-----------------KVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
2-233 |
7.61e-121 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 343.25 E-value: 7.61e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 2 LSNFKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARASGADDVLKIASIHDSLSEAIADCQIVLGASA 81
Cdd:COG0565 1 LDNIRVVLVEPQHPGNIGAAARAMKNFGLSDLRLVNPRGWPDEEARAMASGADDVLENARVVDTLEEALADCDLVVGTTA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 82 RDRTISWPSVTARECAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYELFVASG 161
Cdd:COG0565 81 RPRELRKPVLTPREAAEELLARAAGGKVALVFGRERSGLTNEELALCDALVTIPTNPEYPSLNLAQAVQVVAYELRKAAL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1028371151 162 RqyASSIGDRGEESLATAEQMEGFYLHLQQTMADIGFLQPERSKSIMRRLRRVFNRAWLDTKELDILRGILR 233
Cdd:COG0565 161 E--APPLPPPPEPEPATAEELEGLYEHLEELLDAIGFLDPEKPEKLMRRLRRLFGRARLTEREVRTLRGILR 230
|
|
| PRK15114 |
PRK15114 |
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional |
1-232 |
2.43e-86 |
|
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional
Pssm-ID: 185069 Cd Length: 245 Bit Score: 256.22 E-value: 2.43e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 1 MLSNFKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARASGADDVLKIASIHDSLSEAIADCQIVLGAS 80
Cdd:PRK15114 1 MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNATIVDTLDEALAGCSLVVGTS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 81 ARDRTISWPSVTARECAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYELFVAS 160
Cdd:PRK15114 81 ARSRTLPWPMLDPRECGLKSVAEAANAPVALVFGRERVGLTNDELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1028371151 161 -GRQYASSIGDRGEES-LATAEQMEGFYLHLQQTMADIGFLQPERSKSIMRRLRRVFNRAWLDTKELDILRGIL 232
Cdd:PRK15114 161 lATQENGEPQVEHEETpYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTRARPESQELNILRGIL 234
|
|
| rRNA_methyl_1 |
TIGR00050 |
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of ... |
2-233 |
3.68e-81 |
|
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of S-adenosyl-L-methionine (AdoMet)-dependent methyltransferases, and is now characterized, in E. coli, as a tRNA:Cm32/Um32 methyltransferase. It may be named TrMet(Xm32), or TrmJ, according to the nomenclature style chosen [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 272876 [Multi-domain] Cd Length: 233 Bit Score: 242.69 E-value: 3.68e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 2 LSNFKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARASGADDVLKIASIHDSLSEAIADCQIVLGASA 81
Cdd:TIGR00050 1 LENIRIVLVEPSHPGNIGSIARAMKNMGLTELRLVNPRVKLEEEAYALAAGARDILDNAKVVDTLDEALDDCDFVVGTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 82 RDRTISWPSVTARECAEKWVDVAGgaNIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYELFVASG 161
Cdd:TIGR00050 81 RSRNLQRPMLTPRELAPKLVAEKG--KVALVFGREDSGLTNEELQKCHVLVSIPTSEEYPSLNLSHAVAVILYELRMAWL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1028371151 162 RQYASSIgdrgEESLATAEQMEGFYLHLQQTMADIGFLQPERSKSIMRRLRRVFNRAWLDTKELDILRGILR 233
Cdd:TIGR00050 159 AQQENLS----EMPYATVDDLELLLEHLEETLLSLGFIPEHKPRQVMRKFRRLYGRAGLEKRELHILRGILR 226
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
7-156 |
3.25e-72 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 216.98 E-value: 3.25e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 7 VVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHAD-ATARASGADDVLKIASIHDSLSEAIADCQIVLGASARDRT 85
Cdd:cd18093 3 VVLVEPQHPGNIGAVARAMKNFGLSDLRLVNPRCDDPEEaARALASGAEDVLENAKVYDTLEEALADCDLVVATTARPRG 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1028371151 86 ISWPSVTARECAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYEL 156
Cdd:cd18093 83 LRRPLLTPRELAELLKEHAAGGKVALVFGREDSGLTNEELALCDLLVTIPTNPEYPSLNLAQAVAIVLYEL 153
|
|
| PRK10433 |
PRK10433 |
putative RNA methyltransferase; Provisional |
5-156 |
8.97e-40 |
|
putative RNA methyltransferase; Provisional
Pssm-ID: 236693 Cd Length: 228 Bit Score: 136.66 E-value: 8.97e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 5 FKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKyfPHADATAR--ASGADDVLKIASIHDSLSEAIADCQIVLGASAR 82
Cdd:PRK10433 3 LTIILVAPARAENVGAAARAMKTMGFSELRIVDSQ--AHLEPAARwvAHGSGDILDNAKVFDTLAEALHDVDFTVATTAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 83 DRTISWPSVTAREC----AEK--WVDVAgganiALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYEL 156
Cdd:PRK10433 81 SRAKFHYYATPAELvpllEEKssWMSHA-----ALVFGREDSGLTNEELALADVLTGVPMAADYPSLNLGQAVMVYCYQL 155
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
4-154 |
1.06e-34 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 121.10 E-value: 1.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 4 NFKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATAR--ASGADDVLKIAsIHDSLSEAIADCQ----IVL 77
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPYNPKAIraSAGALFHLPLV-VVDNLEEALKDLKeagyAVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 78 GASARDR---TISWPSvtarecaekwvdvaggaNIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCY 154
Cdd:pfam00588 80 ATSLGGKslyEIDFPK-----------------KVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
7-156 |
3.52e-21 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 86.13 E-value: 3.52e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 7 VVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARAS-GADDVLKIaSIHDSLSEAIADCQivlgasARDRT 85
Cdd:cd18082 2 LVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSrGTHFSVPY-ERVDNFEEYLKSLK------EEGYP 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1028371151 86 ISWPSVTARECAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYEL 156
Cdd:cd18082 75 LIGLELTDGSIPLSEFKFKKPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
5-155 |
2.76e-11 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 59.66 E-value: 2.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 5 FKVVLVETSHPGNIGAVARAMKNMGMnQLRLVTPKYFPHADATARASGAD--DVLKIaSIHDSLS---EAIADCQIVLga 79
Cdd:COG0219 2 LHIVLYEPEIPQNTGNIIRLCAATGA-RLHLIEPLGFSLDDKKLKRAGLDywELVDL-TVHDSWEaflEALPGGRLFL-- 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1028371151 80 sardrtiswpsVTARecAEKWV-DVAGGANIALVFGRENSGLKNHELDL-CQYLLRIPCNAEYSSLNLAAAVQVVCYE 155
Cdd:COG0219 78 -----------FTTK--GTKPYtDVDYQPGDVLLFGRETAGLPEEVLAApADQRLRIPMRPGVRSLNLSNAVAIVLYE 142
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
6-155 |
7.72e-11 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 58.23 E-value: 7.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 6 KVVLVETSHPGNIGAVARAMKNMGMnQLRLVTPKYFPHADATARASGAD--DVLKIaSIHDSLSEAIADCQI--VLGASA 81
Cdd:cd18094 1 NIVLYEPEIPQNTGNIARTCAATGA-RLHLIEPLGFSLDDKRLKRAGLDywDHVDL-TVHDSWEAFLEALPPgrLFLFTT 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1028371151 82 RDRTISWpsvtarecaekwvDVAGGANIALVFGRENSGLKNHELDLC-QYLLRIPCNAEYSSLNLAAAVQVVCYE 155
Cdd:cd18094 79 KGTKPYT-------------DFDFKPGDYLVFGRESTGLPEEILDAFpDRRLRIPMRPKVRSLNLSNSVAIVLYE 140
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
7-156 |
8.65e-10 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 55.51 E-value: 8.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 7 VVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARAS-GAddVLKIASIH-DSLSEAIADCQI----VLGAS 80
Cdd:cd18095 3 LVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASmGA--LFRLPIIRvDDLEELLEELKEagykVVAAD 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1028371151 81 ARDRTISWpsvtarecaekwvDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYEL 156
Cdd:cd18095 81 LDGGSSLY-------------DLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
7-156 |
2.66e-08 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 52.89 E-value: 2.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 7 VVLVETSHPGNIGAVARAMKNMGMNQLrlVTPKyfPHAD----ATARAS-GADDVLKIASIhDSLSEAIADCQ----IVL 77
Cdd:COG0566 118 LVLDGVQDPGNLGAILRSAAAFGVDGV--ILPK--RRADpynpKVVRASaGALFHVPVARV-TNLADALEELKeagfWVV 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 78 GASARdrtiswpsvtarecAEKWV-DVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYEL 156
Cdd:COG0566 193 GTDLD--------------GEASLyEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLYEA 258
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
7-156 |
3.06e-08 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 51.03 E-value: 3.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 7 VVLVETSHPGNIGAVARAMKNMGMNQLRL--VTPkYFPHADATARASGADDVLKIaSIHDSLSEAIADCQivlgasARDR 84
Cdd:cd18097 3 VVLDNLRSAHNVGSIFRTADAAGVEKIYLcgYTP-TPPHPKVAKTALGAEESVPW-EHFEDTLEAVRALK------ARGY 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1028371151 85 TIsWPSVTAREcAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYEL 156
Cdd:cd18097 75 TI-IALETTEN-SVPLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
15-156 |
3.48e-08 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 50.85 E-value: 3.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 15 PGNIGAVARAMKNMGMNQLrlVTPKY-FPHADATAR--ASGADDVLKIASIhDSLSEAIADCQ----IVLGASARDRTIS 87
Cdd:cd18103 11 PHNLGAIIRSAEAFGVDGV--IIPKRrSAPLTPTVAkaSAGALEHLPIARV-TNLARALEELKeagfWIYGADGEAEKSL 87
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1028371151 88 WpsvtarecaekwvDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYEL 156
Cdd:cd18103 88 Y-------------DVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
5-154 |
7.21e-08 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 49.95 E-value: 7.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 5 FKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADA--TARASGADDVLKIASIHDSLSEAIADCQIVlgasar 82
Cdd:cd18098 1 FAIGIENPKTPKNVGTLWRAAGCLGASFVFTIGARYKRRKQStdTSKAWRHIPLFHYDDLEDLAEPLPFGAVLV------ 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1028371151 83 drtiswpSVTARECAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCnaeYSSLNLAAAVQVVCY 154
Cdd:cd18098 75 -------AVELTEGATPLPDFKHPDRAVYLLGPEDGGLPQEVLARCHHVVYLPT---RGSLNVAVAGSIVLY 136
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
5-155 |
2.89e-07 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 48.35 E-value: 2.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 5 FKVVLVETSHPGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARAS-GADDVLKIASIhdSLSEAIADCQivlgasard 83
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASlGAVFTLPVAEA--SSEETLAWLK--------- 69
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1028371151 84 rTISWPSVTARECAEK-WVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYE 155
Cdd:cd18104 70 -ENKIRILATTPKAEKlYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLYE 141
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
7-157 |
3.68e-07 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 48.62 E-value: 3.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 7 VVLVETSHPGNIGAVARAMKNMGMNQLRLV-TPKYFPHADATARasGADDVLKIaSIHDSLSEAIA-----DCQIVlGAS 80
Cdd:cd18092 19 VVLENVHDPHNASAVLRTCDAFGVQDVHVIePKNKFKKNRGVAM--GADKWLDV-HRHDSTEECLAalkeqGYRIV-ATS 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1028371151 81 ARDRTISWPSVTAREcaekwvdvaggaNIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYELF 157
Cdd:cd18092 95 LSPDAVPLDELDYTR------------PTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYELQ 159
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
15-156 |
1.13e-05 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 44.05 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 15 PGNIGAVARAMKNMGMNQLRLVTPKYFPHADATARAS-GADDVLKIASIhDSLSEAIADCQ----IVLGASAR-DRTISW 88
Cdd:cd18105 11 PQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASaGALELMPIYSV-DNLASFLKSSKengwKVVGTSAPpSASSDK 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1028371151 89 PSVTARECAEKWVDvaggANIALVFGRENSGLKNHELDLCQYLLRIPC-----NAEYSSLNLAAAVQVVCYEL 156
Cdd:cd18105 90 KTIPANELSELLLE----KPTILVLGNEGRGLRTNIKNLCDYLVSIPGgrsaeNPGVDSLNVSVAAGILLHSL 158
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
7-155 |
1.57e-04 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 40.83 E-value: 1.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 7 VVLVETSHPGNIGAVARAMKNMGmnqlrlvtpkyfphADATARASGADDVLKIASIHDSLSEAIAdCQIVLGASARDrTI 86
Cdd:cd18107 3 VLFDRPTSPGNLGTIIRSADALG--------------AHGLVVTGHAADVYDPKTIRASTGSLFS-LPIVRVPSNRE-LE 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 87 SWPSvTARECAEKWV----DVAGGANIA---------LVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVC 153
Cdd:cd18107 67 DWVE-ARKARGTPLQlvgtDEHGDHQIAdhdftrptlLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFL 145
|
..
gi 1028371151 154 YE 155
Cdd:cd18107 146 YE 147
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
15-156 |
3.52e-04 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 39.54 E-value: 3.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 15 PGNIGAVARAMKNMGMNQLrLVT--------PKyfphadaTARAS-GADDVLKIAS-IH-DSLSEAIADCQIVLGASARD 83
Cdd:cd18106 11 PGNLGSILRSAAAAGCSKV-LLTkgcvdpwePK-------VLRAGaGAHFRLPIYGnLSwDDIPNYLPDDSKVFLADNNL 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1028371151 84 RTISWPSVtarecaeKWvdvaGGANIALVFGRENSGLKNHELDLCQYL----LRIPCNAEYSSLNLAAAVQVVCYEL 156
Cdd:cd18106 83 PVQPYDSI-------DY----CSGPIVLVIGGETHGVSPEAYKLAHSTggsrVHIPLANGVDSLNSAVAASILLFEM 148
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
5-157 |
4.14e-04 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 40.40 E-value: 4.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028371151 5 FKVVLVETSHPGNIGAVARAMKNMGMNQLrlVTPKYFPHAD-ATAR--ASGADDVLKIASIhDSLSEAIADCQivlgasa 81
Cdd:TIGR00186 91 FLLILDEITDPHNLGAILRTAEAFGVDGV--ILPKRRSAPLnSTVVktSSGAVEYVPLARV-TNLSRTITKLK------- 160
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1028371151 82 rDRTIsWPSVTARECAEKWVDVAGGANIALVFGRENSGLKNHELDLCQYLLRIPCNAEYSSLNLAAAVQVVCYELF 157
Cdd:TIGR00186 161 -ESGF-WTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIK 234
|
|
| |
