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Conserved domains on  [gi|1028513014|gb|OAI91366|]
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hypothetical protein AYO27_24435 [Rhizobium sp. GHKF11]

Protein Classification

DUF4214 and AdoMet_MTases domain-containing protein( domain architecture ID 10742852)

DUF4214 and AdoMet_MTases domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 198-330 2.35e-19

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


:

Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 83.14  E-value: 2.35e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 198 MTELDRRHRgpsdvVRKQLEAYIPHLVLDvgNGKVLDIGCGRGTFLEILRDNGVEGVGLEINEEQRNECVSKG--LVVHL 275
Cdd:COG2227     1 MSDPDARDF-----WDRRLAALLARLLPA--GGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAaeLNVDF 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1028513014 276 EDAFVFLKNCDENSFATITLFHVIEHLefEDLILLLNEIYRVLAFGGTLLMETPN 330
Cdd:COG2227    74 VQGDLEDLPLEDGSFDLVICSEVLEHL--PDPAALLRELARLLKPGGLLLLSTPN 126
DUF4214 super family cl16493
Domain of unknown function (DUF4214); This domain is found on a variety of different proteins ...
 47-94 2.43e-03

Domain of unknown function (DUF4214); This domain is found on a variety of different proteins including transferases, and allergen V5/Tpx-1 related proteins.


The actual alignment was detected with superfamily member pfam13946:

Pssm-ID: 433598 [Multi-domain]  Cd Length: 72  Bit Score: 36.50  E-value: 2.43e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1028513014  47 SDFLKCIYRILLHRSCCGSELEHYKGLLTDG-ILRTDIMRGILQSEEFK 94
Cdd:pfam13946  21 EDFVTTLYQNVLDREPDSAGLNYWAGQLASGaESRYEVLLGFSESAEFK 69
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 198-330 2.35e-19

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 83.14  E-value: 2.35e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 198 MTELDRRHRgpsdvVRKQLEAYIPHLVLDvgNGKVLDIGCGRGTFLEILRDNGVEGVGLEINEEQRNECVSKG--LVVHL 275
Cdd:COG2227     1 MSDPDARDF-----WDRRLAALLARLLPA--GGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAaeLNVDF 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1028513014 276 EDAFVFLKNCDENSFATITLFHVIEHLefEDLILLLNEIYRVLAFGGTLLMETPN 330
Cdd:COG2227    74 VQGDLEDLPLEDGSFDLVICSEVLEHL--PDPAALLRELARLLKPGGLLLLSTPN 126
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 212-366 7.45e-15

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 71.69  E-value: 7.45e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 212 VRKQLEAYIPHLVLDVG-----NGKVLDIGCGRGTFLEILRDNGVEGVGLEINEEQRNECVSKglvVHLEDAFVFLKNCD 286
Cdd:pfam13489   1 YAHQRERLLADLLLRLLpklpsPGRVLDFGCGTGIFLRLLRAQGFSVTGVDPSPIAIERALLN---VRFDQFDEQEAAVP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 287 ENSFATITLFHVIEHleFEDLILLLNEIYRVLAFGGTLLMETPNS----ENLFVSTFFFNVDPTHVKPITYQYISTVLEV 362
Cdd:pfam13489  78 AGKFDVIVAREVLEH--VPDPPALLRQIAALLKPGGLLLLSTPLAsdeaDRLLLEWPYLRPRNGHISLFSARSLKRLLEE 155


                  ....
gi 1028513014 363 IGYR 366
Cdd:pfam13489 156 AGFE 159
metW TIGR02081
methionine biosynthesis protein MetW; This protein is found alongside MetX, of the enzyme that ...
 231-317 2.87e-11

methionine biosynthesis protein MetW; This protein is found alongside MetX, of the enzyme that acylates homoserine as a first step toward methionine biosynthesis, in many species. It appears to act in methionine biosynthesis but is not fully characterized. [Amino acid biosynthesis, Aspartate family]


Pssm-ID: 273958  Cd Length: 194  Bit Score: 62.38  E-value: 2.87e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 231 KVLDIGCGRGTFLEILRDN-GVEGVGLEINEEQRNECVSKGLVVHLEDAFVFLKNCDENSFATITLFHVIEHLEFEDLIl 309
Cdd:TIGR02081  16 RVLDLGCGDGELLALLRDEkQVRGYGIEIDQDGVLACVARGVNVIQGDLDEGLEAFPDKSFDYVILSQTLQATRNPEEI- 94


                  ....*...
gi 1028513014 310 lLNEIYRV 317
Cdd:TIGR02081  95 -LDEMLRV 101
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 231-327 2.18e-07

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 48.97  E-value: 2.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 231 KVLDIGCGRGTF-LEILRDNGVEGVGLEINEEQ-------RNECVSKGLVVHLEDAFVFLKNcDENSFATITLFHVIEHL 302
Cdd:cd02440     1 RVLDLGCGTGALaLALASGPGARVTGVDISPVAlelarkaAAALLADNVEVLKGDAEELPPE-ADESFDVIISDPPLHHL 79

                          90       100
                  ....*....|....*....|....*
gi 1028513014 303 eFEDLILLLNEIYRVLAFGGTLLME 327
Cdd:cd02440    80 -VEDLARFLEEARRLLKPGGVLVLT 103
PRK08317 PRK08317
hypothetical protein; Provisional
 225-326 1.67e-03

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 39.92  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 225 LDVGNG-KVLDIGCGRGTFL-EILRDNGVEG--VGLEINEE----QRNECVSKGLVV--HLEDA----FvflkncDENSF 290
Cdd:PRK08317   15 LAVQPGdRVLDVGCGPGNDArELARRVGPEGrvVGIDRSEAmlalAKERAAGLGPNVefVRGDAdglpF------PDGSF 88

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1028513014 291 ATITLFHVIEHLEfeDLILLLNEIYRVLAFGGTLLM 326
Cdd:PRK08317   89 DAVRSDRVLQHLE--DPARALAEIARVLRPGGRVVV 122
DUF4214 pfam13946
Domain of unknown function (DUF4214); This domain is found on a variety of different proteins ...
 47-94 2.43e-03

Domain of unknown function (DUF4214); This domain is found on a variety of different proteins including transferases, and allergen V5/Tpx-1 related proteins.


Pssm-ID: 433598 [Multi-domain]  Cd Length: 72  Bit Score: 36.50  E-value: 2.43e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1028513014  47 SDFLKCIYRILLHRSCCGSELEHYKGLLTDG-ILRTDIMRGILQSEEFK 94
Cdd:pfam13946  21 EDFVTTLYQNVLDREPDSAGLNYWAGQLASGaESRYEVLLGFSESAEFK 69
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 198-330 2.35e-19

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 83.14  E-value: 2.35e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 198 MTELDRRHRgpsdvVRKQLEAYIPHLVLDvgNGKVLDIGCGRGTFLEILRDNGVEGVGLEINEEQRNECVSKG--LVVHL 275
Cdd:COG2227     1 MSDPDARDF-----WDRRLAALLARLLPA--GGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAaeLNVDF 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1028513014 276 EDAFVFLKNCDENSFATITLFHVIEHLefEDLILLLNEIYRVLAFGGTLLMETPN 330
Cdd:COG2227    74 VQGDLEDLPLEDGSFDLVICSEVLEHL--PDPAALLRELARLLKPGGLLLLSTPN 126
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 212-366 7.45e-15

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 71.69  E-value: 7.45e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 212 VRKQLEAYIPHLVLDVG-----NGKVLDIGCGRGTFLEILRDNGVEGVGLEINEEQRNECVSKglvVHLEDAFVFLKNCD 286
Cdd:pfam13489   1 YAHQRERLLADLLLRLLpklpsPGRVLDFGCGTGIFLRLLRAQGFSVTGVDPSPIAIERALLN---VRFDQFDEQEAAVP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 287 ENSFATITLFHVIEHleFEDLILLLNEIYRVLAFGGTLLMETPNS----ENLFVSTFFFNVDPTHVKPITYQYISTVLEV 362
Cdd:pfam13489  78 AGKFDVIVAREVLEH--VPDPPALLRQIAALLKPGGLLLLSTPLAsdeaDRLLLEWPYLRPRNGHISLFSARSLKRLLEE 155


                  ....
gi 1028513014 363 IGYR 366
Cdd:pfam13489 156 AGFE 159
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 229-326 1.51e-14

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 70.41  E-value: 1.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 229 NGKVLDIGCGRGTFLEILRDNGVEGVGLEINEEQ----RNECVSKGLVVHLEDAFVFLKNCDENSFATITLFHVIEHleF 304
Cdd:COG2226    23 GARVLDLGCGTGRLALALAERGARVTGVDISPEMlelaRERAAEAGLNVEFVVGDAEDLPFPDGSFDLVISSFVLHH--L 100

                          90       100
                  ....*....|....*....|..
gi 1028513014 305 EDLILLLNEIYRVLAFGGTLLM 326
Cdd:COG2226   101 PDPERALAEIARVLKPGGRLVV 122
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 232-322 1.17e-12

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 63.35  E-value: 1.17e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 232 VLDIGCGRGTF-LEILRDNGVEGVGLEINEEQ----RNECVSKGLVVHLEDAFVFLKNCDENSFATITLFHVIEHLEFED 306
Cdd:pfam13649   1 VLDLGCGTGRLtLALARRGGARVTGVDLSPEMleraRERAAEAGLNVEFVQGDAEDLPFPDGSFDLVVSSGVLHHLPDPD 80

                          90
                  ....*....|....*.
gi 1028513014 307 LILLLNEIYRVLAFGG 322
Cdd:pfam13649  81 LEAALREIARVLKPGG 96
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 213-329 1.36e-12

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 65.34  E-value: 1.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 213 RKQLEAYIPHLVLDVGnGKVLDIGCGRGTFLEIL-RDNGVEGVGLEINEEQ--------RNECVSKGLVVHLEDAFVFLk 283
Cdd:COG2230    37 EAKLDLILRKLGLKPG-MRVLDIGCGWGGLALYLaRRYGVRVTGVTLSPEQleyareraAEAGLADRVEVRLADYRDLP- 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1028513014 284 ncDENSFATITLFHVIEHLEFEDLILLLNEIYRVLAFGGTLLMETP 329
Cdd:COG2230   115 --ADGQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLLHTP 158
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 202-327 1.94e-12

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 65.71  E-value: 1.94e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 202 DRRHRGPSDVVRKQLEAYIPHLVldvGNGKVLDIGCGRGTFLEILRD-NGVEGVGLEINEEQ----RNECVSKGLV---V 273
Cdd:COG0500     3 DSYYSDELLPGLAALLALLERLP---KGGRVLDLGCGTGRNLLALAArFGGRVIGIDLSPEAialaRARAAKAGLGnveF 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1028513014 274 HLEDAFVFLKNCDEnSFATITLFHVIEHLEFEDLILLLNEIYRVLAFGGTLLME 327
Cdd:COG0500    80 LVADLAELDPLPAE-SFDLVVAFGVLHHLPPEEREALLRELARALKPGGVLLLS 132
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
195-333 3.61e-12

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 64.63  E-value: 3.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 195 QDIMTELDrrHRGPSDVVRKQLEAYIPHlvldvGNGKVLDIGCGRGTFLEILRDNGVEGVGLEINEEQRNECVSKGLVVH 274
Cdd:COG4976    20 AALVEDLG--YEAPALLAEELLARLPPG-----PFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAREKGVYDR 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 275 LEDA-FVFLKNCDEnSFATITLFHVIEHleFEDLILLLNEIYRVLAFGGTLLMETPNSEN 333
Cdd:COG4976    93 LLVAdLADLAEPDG-RFDLIVAADVLTY--LGDLAAVFAGVARALKPGGLFIFSVEDADG 149
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 233-326 8.82e-12

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 61.14  E-value: 8.82e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 233 LDIGCGRGTFLEILRDNGVEGVGLEINEEQ----RNECVSKGLVVHLEDA----FvflkncDENSFATITLFHVIEHleF 304
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMlelaREKAPREGLTFVVGDAedlpF------PDNSFDLVLSSEVLHH--V 72

                          90       100
                  ....*....|....*....|..
gi 1028513014 305 EDLILLLNEIYRVLAFGGTLLM 326
Cdd:pfam08241  73 EDPERALREIARVLKPGGILII 94
metW TIGR02081
methionine biosynthesis protein MetW; This protein is found alongside MetX, of the enzyme that ...
 231-317 2.87e-11

methionine biosynthesis protein MetW; This protein is found alongside MetX, of the enzyme that acylates homoserine as a first step toward methionine biosynthesis, in many species. It appears to act in methionine biosynthesis but is not fully characterized. [Amino acid biosynthesis, Aspartate family]


Pssm-ID: 273958  Cd Length: 194  Bit Score: 62.38  E-value: 2.87e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 231 KVLDIGCGRGTFLEILRDN-GVEGVGLEINEEQRNECVSKGLVVHLEDAFVFLKNCDENSFATITLFHVIEHLEFEDLIl 309
Cdd:TIGR02081  16 RVLDLGCGDGELLALLRDEkQVRGYGIEIDQDGVLACVARGVNVIQGDLDEGLEAFPDKSFDYVILSQTLQATRNPEEI- 94


                  ....*...
gi 1028513014 310 lLNEIYRV 317
Cdd:TIGR02081  95 -LDEMLRV 101
MetW pfam07021
Methionine biosynthesis protein MetW; This family consists of several bacterial and one ...
 231-317 4.62e-11

Methionine biosynthesis protein MetW; This family consists of several bacterial and one archaeal methionine biosynthesis MetW proteins. Biosynthesis of methionine from homoserine in Pseudomonas putida takes place in three steps. The first step is the acylation of homoserine to yield an acyl-L-homoserine. This reaction is catalyzed by the products of the metXW genes and is equivalent to the first step in enterobacteria, gram-positive bacteria and fungi, except that in these microorganizms the reaction is catalyzed by a single polypeptide (the product of the metA gene in Escherichia coli and the met5 gene product in Neurospora crassa). In Pseudomonas putida, as in gram-positive bacteria and certain fungi, the second and third steps are a direct sulfhydrylation that converts the O-acyl-L-homoserine into homocysteine and further methylation to yield methionine. The latter reaction can be mediated by either of the two methionine synthetases present in the cells.


Pssm-ID: 399779  Cd Length: 193  Bit Score: 61.70  E-value: 4.62e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 231 KVLDIGCGRGTFLEILRDN-GVEGVGLEINEEQRNECVSKGLVVHLEDAFVFLKNCDENSFATITLFHVIEHLEFEDLIl 309
Cdd:pfam07021  16 RVLDLGCGDGTLLYLLKEEkGVDGYGIELDAAGVAECVAKGLYVIQGDLDEGLEHFPDKSFDYVILSQTLQATRNPREV- 94


                  ....*...
gi 1028513014 310 lLNEIYRV 317
Cdd:pfam07021  95 -LDEMLRI 101
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 228-333 1.70e-08

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 53.19  E-value: 1.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 228 GNGKVLDIGCGRGTFLEILRDN---GVEGVGLEINEEQ----RNECVSKGL---VVHLEDAFVFLKNCDENSFATITLFH 297
Cdd:pfam13847   3 KGMRVLDLGCGTGHLSFELAEElgpNAEVVGIDISEEAiekaRENAQKLGFdnvEFEQGDIEELPELLEDDKFDVVISNC 82

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1028513014 298 VIEHLEFEDLILllNEIYRVLAFGGTLLMETPNSEN 333
Cdd:pfam13847  83 VLNHIPDPDKVL--QEILRVLKPGGRLIISDPDSLA 116
COG4627 COG4627
Predicted SAM-depedendent methyltransferase [General function prediction only];
286-330 2.75e-08

Predicted SAM-depedendent methyltransferase [General function prediction only];


Pssm-ID: 443666 [Multi-domain]  Cd Length: 161  Bit Score: 52.95  E-value: 2.75e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1028513014 286 DENSFATITLFHVIEHLEFEDLILLLNEIYRVLAFGGTLLMETPN 330
Cdd:COG4627    43 PDNSVDAIYSSHVLEHLDYEEAPLALKECYRVLKPGGILRIVVPD 87
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 231-327 2.18e-07

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 48.97  E-value: 2.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 231 KVLDIGCGRGTF-LEILRDNGVEGVGLEINEEQ-------RNECVSKGLVVHLEDAFVFLKNcDENSFATITLFHVIEHL 302
Cdd:cd02440     1 RVLDLGCGTGALaLALASGPGARVTGVDISPVAlelarkaAAALLADNVEVLKGDAEELPPE-ADESFDVIISDPPLHHL 79

                          90       100
                  ....*....|....*....|....*
gi 1028513014 303 eFEDLILLLNEIYRVLAFGGTLLME 327
Cdd:cd02440    80 -VEDLARFLEEARRLLKPGGVLVLT 103
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
228-328 5.22e-07

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 47.51  E-value: 5.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 228 GNGKVLDIGCGRGTFLEILRDN--GVEGVGLEINEEQRNECVSK--GLVVHLEDAFVFLKncdENSFATITLFHVIEHLe 303
Cdd:COG4106     1 PPRRVLDLGCGTGRLTALLAERfpGARVTGVDLSPEMLARARARlpNVRFVVADLRDLDP---PEPFDLVVSNAALHWL- 76

                          90       100
                  ....*....|....*....|....*
gi 1028513014 304 fEDLILLLNEIYRVLAFGGTLLMET 328
Cdd:COG4106    77 -PDHAALLARLAAALAPGGVLAVQV 100
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 233-324 3.72e-06

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 45.05  E-value: 3.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 233 LDIGCGRGTFLEILRDN--GVEGVGLEINEEQ-----RNECVSKGLVVHLEDAFVF-LKNCDENSFATITLFHVIEHLef 304
Cdd:pfam08242   1 LEIGCGTGTLLRALLEAlpGLEYTGLDISPAAleaarERLAALGLLNAVRVELFQLdLGELDPGSFDVVVASNVLHHL-- 78

                          90       100
                  ....*....|....*....|
gi 1028513014 305 EDLILLLNEIYRVLAFGGTL 324
Cdd:pfam08242  79 ADPRAVLRNIRRLLKPGGVL 98
PRK08317 PRK08317
hypothetical protein; Provisional
 225-326 1.67e-03

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 39.92  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513014 225 LDVGNG-KVLDIGCGRGTFL-EILRDNGVEG--VGLEINEE----QRNECVSKGLVV--HLEDA----FvflkncDENSF 290
Cdd:PRK08317   15 LAVQPGdRVLDVGCGPGNDArELARRVGPEGrvVGIDRSEAmlalAKERAAGLGPNVefVRGDAdglpF------PDGSF 88

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1028513014 291 ATITLFHVIEHLEfeDLILLLNEIYRVLAFGGTLLM 326
Cdd:PRK08317   89 DAVRSDRVLQHLE--DPARALAEIARVLRPGGRVVV 122
DUF4214 pfam13946
Domain of unknown function (DUF4214); This domain is found on a variety of different proteins ...
 47-94 2.43e-03

Domain of unknown function (DUF4214); This domain is found on a variety of different proteins including transferases, and allergen V5/Tpx-1 related proteins.


Pssm-ID: 433598 [Multi-domain]  Cd Length: 72  Bit Score: 36.50  E-value: 2.43e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1028513014  47 SDFLKCIYRILLHRSCCGSELEHYKGLLTDG-ILRTDIMRGILQSEEFK 94
Cdd:pfam13946  21 EDFVTTLYQNVLDREPDSAGLNYWAGQLASGaESRYEVLLGFSESAEFK 69
PRK11705 PRK11705
cyclopropane fatty acyl phospholipid synthase;
231-277 7.31e-03

cyclopropane fatty acyl phospholipid synthase;


Pssm-ID: 183282  Cd Length: 383  Bit Score: 38.29  E-value: 7.31e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1028513014 231 KVLDIGCGRGTFLEILRDN-GVEGVGLEINEEQ----RNECvsKGLVV--HLED 277
Cdd:PRK11705  170 RVLDIGCGWGGLARYAAEHyGVSVVGVTISAEQqklaQERC--AGLPVeiRLQD 221
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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