NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1028513479|gb|OAI91817|]
View 

hypothetical protein AYO27_23680 [Rhizobium sp. GHKF11]

Protein Classification

DUF2493 domain-containing protein( domain architecture ID 10566435)

DUF2493 domain-containing protein similar to Mycobacterium virus gene 61 protein (Gp61)

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
YAcAr pfam10686
YspA, cpYpsA-related SLOG family; Family in the SLOG superfamily, related to YspA and cpYpsA ...
 196-262 1.29e-31

YspA, cpYpsA-related SLOG family; Family in the SLOG superfamily, related to YspA and cpYpsA families and shows associations with NAD utilization and ADP-ribosylation domains including NUDIX, NADAR and MACRO. Members of this family are predicted to function as sensors of nucleotide, nucleotide-derived ligands, or nucleic acids, which are potentially processed/modified by associating effectors. Also associates in a distinct system with a phosphoribosyltransferase (PRTase) domain.


:

Pssm-ID: 431435 [Multi-domain]  Cd Length: 66  Bit Score: 112.63  E-value: 1.29e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1028513479 196 TKIAFAGGMDYNDHERIWAKLDQAHAKHPDMVLLHGGSpKGAERIAACWAEARQVTQITFKPNWTKH 262
Cdd:pfam10686   1 PRVLVTGGRDFNDHELIWAALDKVRARHPDMVLVHGGA-KGADRIAARWARERGVPQVRFPPDWKRH 66
metL super family cl35835
bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional
 100-251 1.11e-03

bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional


The actual alignment was detected with superfamily member PRK09466:

Pssm-ID: 236530 [Multi-domain]  Cd Length: 810  Bit Score: 40.68  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513479 100 EEAQRTGQREQDG-------SEVKSVELERLIAEGITLLERrnsfefmrdFSADLYEAQT------GSSWRPRSGSKV-N 165
Cdd:PRK09466   72 HQVQQTLRRYQQDliegllpAEQARSLLSRLISDLERLAAL---------LDGGINDAQYaevvghGEVWSARLMAALlN 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513479 166 HANMTAAMIDSRDFLSARRRAETEVlipagtkiafaggmdynDHERIWAKLDQAHAKHP----------------DMVLL 229
Cdd:PRK09466  143 QQGLPAAWLDARSFLRAERAAQPQV-----------------DEGLSYPLLQQLLAQHPgkrlvvtgfisrneagETVLL 205

                         170       180
                  ....*....|....*....|...
gi 1028513479 230 -HGGSPKGAERIAAcWAEARQVT 251
Cdd:PRK09466  206 gRNGSDYSATLIGA-LAGVERVT 227
 
Name Accession Description Interval E-value
YAcAr pfam10686
YspA, cpYpsA-related SLOG family; Family in the SLOG superfamily, related to YspA and cpYpsA ...
 196-262 1.29e-31

YspA, cpYpsA-related SLOG family; Family in the SLOG superfamily, related to YspA and cpYpsA families and shows associations with NAD utilization and ADP-ribosylation domains including NUDIX, NADAR and MACRO. Members of this family are predicted to function as sensors of nucleotide, nucleotide-derived ligands, or nucleic acids, which are potentially processed/modified by associating effectors. Also associates in a distinct system with a phosphoribosyltransferase (PRTase) domain.


Pssm-ID: 431435 [Multi-domain]  Cd Length: 66  Bit Score: 112.63  E-value: 1.29e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1028513479 196 TKIAFAGGMDYNDHERIWAKLDQAHAKHPDMVLLHGGSpKGAERIAACWAEARQVTQITFKPNWTKH 262
Cdd:pfam10686   1 PRVLVTGGRDFNDHELIWAALDKVRARHPDMVLVHGGA-KGADRIAARWARERGVPQVRFPPDWKRH 66
metL PRK09466
bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional
 100-251 1.11e-03

bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional


Pssm-ID: 236530 [Multi-domain]  Cd Length: 810  Bit Score: 40.68  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513479 100 EEAQRTGQREQDG-------SEVKSVELERLIAEGITLLERrnsfefmrdFSADLYEAQT------GSSWRPRSGSKV-N 165
Cdd:PRK09466   72 HQVQQTLRRYQQDliegllpAEQARSLLSRLISDLERLAAL---------LDGGINDAQYaevvghGEVWSARLMAALlN 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513479 166 HANMTAAMIDSRDFLSARRRAETEVlipagtkiafaggmdynDHERIWAKLDQAHAKHP----------------DMVLL 229
Cdd:PRK09466  143 QQGLPAAWLDARSFLRAERAAQPQV-----------------DEGLSYPLLQQLLAQHPgkrlvvtgfisrneagETVLL 205

                         170       180
                  ....*....|....*....|...
gi 1028513479 230 -HGGSPKGAERIAAcWAEARQVT 251
Cdd:PRK09466  206 gRNGSDYSATLIGA-LAGVERVT 227
 
Name Accession Description Interval E-value
YAcAr pfam10686
YspA, cpYpsA-related SLOG family; Family in the SLOG superfamily, related to YspA and cpYpsA ...
 196-262 1.29e-31

YspA, cpYpsA-related SLOG family; Family in the SLOG superfamily, related to YspA and cpYpsA families and shows associations with NAD utilization and ADP-ribosylation domains including NUDIX, NADAR and MACRO. Members of this family are predicted to function as sensors of nucleotide, nucleotide-derived ligands, or nucleic acids, which are potentially processed/modified by associating effectors. Also associates in a distinct system with a phosphoribosyltransferase (PRTase) domain.


Pssm-ID: 431435 [Multi-domain]  Cd Length: 66  Bit Score: 112.63  E-value: 1.29e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1028513479 196 TKIAFAGGMDYNDHERIWAKLDQAHAKHPDMVLLHGGSpKGAERIAACWAEARQVTQITFKPNWTKH 262
Cdd:pfam10686   1 PRVLVTGGRDFNDHELIWAALDKVRARHPDMVLVHGGA-KGADRIAARWARERGVPQVRFPPDWKRH 66
metL PRK09466
bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional
 100-251 1.11e-03

bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional


Pssm-ID: 236530 [Multi-domain]  Cd Length: 810  Bit Score: 40.68  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513479 100 EEAQRTGQREQDG-------SEVKSVELERLIAEGITLLERrnsfefmrdFSADLYEAQT------GSSWRPRSGSKV-N 165
Cdd:PRK09466   72 HQVQQTLRRYQQDliegllpAEQARSLLSRLISDLERLAAL---------LDGGINDAQYaevvghGEVWSARLMAALlN 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1028513479 166 HANMTAAMIDSRDFLSARRRAETEVlipagtkiafaggmdynDHERIWAKLDQAHAKHP----------------DMVLL 229
Cdd:PRK09466  143 QQGLPAAWLDARSFLRAERAAQPQV-----------------DEGLSYPLLQQLLAQHPgkrlvvtgfisrneagETVLL 205

                         170       180
                  ....*....|....*....|...
gi 1028513479 230 -HGGSPKGAERIAAcWAEARQVT 251
Cdd:PRK09466  206 gRNGSDYSATLIGA-LAGVERVT 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH