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dihydroxy-acid dehydratase [Vibrio tasmaniensis]
Protein Classification
dihydroxy-acid dehydratase ( domain architecture ID 10013972 )
dihydroxy-acid dehydratase catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
List of domain hits
Name
Accession
Description
Interval
E-value
PRK12448
PRK12448 dihydroxy-acid dehydratase; Provisional
2-613
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237104
Cd Length: 615
Bit Score: 1366.07
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 2 P I YRS A TTTHGRNMAGARALWRATG V KD D DFGKPIIAVVNSFTQFVPGHVHLKD M GQLVA G EIE K AGG I AKEFNTIAVDD 81
Cdd:PRK12448 1 P K YRS R TTTHGRNMAGARALWRATG M KD E DFGKPIIAVVNSFTQFVPGHVHLKD L GQLVA R EIE A AGG V AKEFNTIAVDD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 82 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM M MAA M RLNIPV I FVSGGPMEAGKTKLSD Q IIK 161
Cdd:PRK12448 81 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM L MAA L RLNIPV V FVSGGPMEAGKTKLSD K IIK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 162 LDLVDAM IQG ADP TI SDE QSE Q V ERSACPTCGSCSGMFTANSMNCLTEALGLS Q PGNGS M LATHADR EE LF IN AG K RIV D 241
Cdd:PRK12448 161 LDLVDAM VAA ADP SV SDE DVA Q I ERSACPTCGSCSGMFTANSMNCLTEALGLS L PGNGS L LATHADR KQ LF LE AG R RIV E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 242 L T KRYYEQDDES A LPR N IA NR AAF D NAM A LDIAMGGS S NTVLHLLAAAQE GDI DF D M D DID AM SR R VP H LCKVAP S T P KY 321
Cdd:PRK12448 241 L A KRYYEQDDES V LPR S IA TK AAF E NAM T LDIAMGGS T NTVLHLLAAAQE AEV DF T M A DID RL SR K VP C LCKVAP N T Q KY 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 322 HMEDVHRAGG V M A ILGELDRAGLL NNQTR TV L GL SMQ E Q L A Q Y DIM Q T E DEAV LK FFRA G P A GIRTT K AFSQDCRWD R LD 401
Cdd:PRK12448 321 HMEDVHRAGG I M G ILGELDRAGLL HTDVP TV H GL TLG E A L D Q W DIM R T Q DEAV KE FFRA A P G GIRTT V AFSQDCRWD S LD 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 402 D DR KE GCIR TK E N A F S QE GGLAVL S GNIA V DGCIVKTAGVDE EN LKF Q GPA I VFESQD T AVE G IL A GKVKAG E VVVIRYE 481
Cdd:PRK12448 401 T DR EN GCIR SV E H A Y S KD GGLAVL Y GNIA E DGCIVKTAGVDE SI LKF T GPA R VFESQD D AVE A IL G GKVKAG D VVVIRYE 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 482 GPKGGPGMQEMLYPT T YLKS M GLGK S CAL L TDGRFSGGTSGLSIGH A SPEAASGG V IGLV NT GDII T IDIP S RSI T L D V P 561
Cdd:PRK12448 481 GPKGGPGMQEMLYPT S YLKS K GLGK A CAL I TDGRFSGGTSGLSIGH V SPEAASGG A IGLV ED GDII E IDIP N RSI N L L V S 560
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 1040425478 562 EA EL T ARR EK Q D A L G --- WKP E NR Q R E VSFALKAYA SM ATSADKGAVRDKSKL E G 613
Cdd:PRK12448 561 DE EL A ARR AA Q E A R G dka WKP K NR E R K VSFALKAYA AL ATSADKGAVRDKSKL G G 615
Name
Accession
Description
Interval
E-value
PRK12448
PRK12448 dihydroxy-acid dehydratase; Provisional
2-613
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237104
Cd Length: 615
Bit Score: 1366.07
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 2 P I YRS A TTTHGRNMAGARALWRATG V KD D DFGKPIIAVVNSFTQFVPGHVHLKD M GQLVA G EIE K AGG I AKEFNTIAVDD 81
Cdd:PRK12448 1 P K YRS R TTTHGRNMAGARALWRATG M KD E DFGKPIIAVVNSFTQFVPGHVHLKD L GQLVA R EIE A AGG V AKEFNTIAVDD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 82 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM M MAA M RLNIPV I FVSGGPMEAGKTKLSD Q IIK 161
Cdd:PRK12448 81 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM L MAA L RLNIPV V FVSGGPMEAGKTKLSD K IIK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 162 LDLVDAM IQG ADP TI SDE QSE Q V ERSACPTCGSCSGMFTANSMNCLTEALGLS Q PGNGS M LATHADR EE LF IN AG K RIV D 241
Cdd:PRK12448 161 LDLVDAM VAA ADP SV SDE DVA Q I ERSACPTCGSCSGMFTANSMNCLTEALGLS L PGNGS L LATHADR KQ LF LE AG R RIV E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 242 L T KRYYEQDDES A LPR N IA NR AAF D NAM A LDIAMGGS S NTVLHLLAAAQE GDI DF D M D DID AM SR R VP H LCKVAP S T P KY 321
Cdd:PRK12448 241 L A KRYYEQDDES V LPR S IA TK AAF E NAM T LDIAMGGS T NTVLHLLAAAQE AEV DF T M A DID RL SR K VP C LCKVAP N T Q KY 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 322 HMEDVHRAGG V M A ILGELDRAGLL NNQTR TV L GL SMQ E Q L A Q Y DIM Q T E DEAV LK FFRA G P A GIRTT K AFSQDCRWD R LD 401
Cdd:PRK12448 321 HMEDVHRAGG I M G ILGELDRAGLL HTDVP TV H GL TLG E A L D Q W DIM R T Q DEAV KE FFRA A P G GIRTT V AFSQDCRWD S LD 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 402 D DR KE GCIR TK E N A F S QE GGLAVL S GNIA V DGCIVKTAGVDE EN LKF Q GPA I VFESQD T AVE G IL A GKVKAG E VVVIRYE 481
Cdd:PRK12448 401 T DR EN GCIR SV E H A Y S KD GGLAVL Y GNIA E DGCIVKTAGVDE SI LKF T GPA R VFESQD D AVE A IL G GKVKAG D VVVIRYE 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 482 GPKGGPGMQEMLYPT T YLKS M GLGK S CAL L TDGRFSGGTSGLSIGH A SPEAASGG V IGLV NT GDII T IDIP S RSI T L D V P 561
Cdd:PRK12448 481 GPKGGPGMQEMLYPT S YLKS K GLGK A CAL I TDGRFSGGTSGLSIGH V SPEAASGG A IGLV ED GDII E IDIP N RSI N L L V S 560
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 1040425478 562 EA EL T ARR EK Q D A L G --- WKP E NR Q R E VSFALKAYA SM ATSADKGAVRDKSKL E G 613
Cdd:PRK12448 561 DE EL A ARR AA Q E A R G dka WKP K NR E R K VSFALKAYA AL ATSADKGAVRDKSKL G G 615
IlvD
COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, ...
1-609
0e+00
Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; Dihydroxyacid dehydratase/phosphogluconate dehydratase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439899
Cd Length: 558
Bit Score: 972.18
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 1 MP IY RS A T T T H GR NM A G ARAL W RATG VK D D DFGKPII AVV NS FTQF VPGHVHL K D MGQL V AGE I EK AGG IAK EFNTIAV D 80
Cdd:COG0129 1 MP KM RS D T V T K GR ER A P ARAL L RATG LT D E DFGKPII GIA NS WNEI VPGHVHL D D LAEA V KEG I RA AGG VPF EFNTIAV S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 81 DGIAMGH G GM L YSLPSRELIADS V E Y MVNAHC A D AM VCI SN CDKITPGM M MAA M RLNIP V IFV S GGPM EA GK TK l SDQII 160
Cdd:COG0129 81 DGIAMGH E GM R YSLPSRELIADS I E T MVNAHC F D GL VCI PG CDKITPGM L MAA A RLNIP S IFV Y GGPM LP GK YD - GKDLD 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 161 KL D LVD A MIQG A DPT ISDE QSEQV ER S ACP T CGSCSGMFTAN S M N CLTEALGLS Q PG N G SML A TH A D R EE L FIN AG K RIV 240
Cdd:COG0129 160 IV D VFE A VGAY A AGK ISDE ELKEI ER N ACP G CGSCSGMFTAN T M A CLTEALGLS L PG S G TIP A VS A E R RR L ARE AG R RIV 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 241 D L TKR yyeqdde SAL PR N I AN R A AF D NA M A L D I A M GGS S NTVLHLLA A A Q E GDI D FDM DD I D AM SRR V PHLC KVA PS T p K 320
Cdd:COG0129 240 E L VEK ------- DIK PR D I LT R E AF E NA I A V D M A L GGS T NTVLHLLA I A H E AGV D LTL DD F D RI SRR T PHLC DLK PS G - K 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 321 YHMED V HRAGG VM A ILG EL DR AGLL NNQTR TV L G LSMQ E Q LA QY DI mqtedeavlkffragpagirttkafsqdcrwdrl 400
Cdd:COG0129 312 YHMED L HRAGG IP A VMK EL LD AGLL HGDCL TV T G KTLA E N LA DA DI ---------------------------------- 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 401 dd DR KEGC IR TKE N AF S QE GGLA V L S GN I A V DG CI VKTAGVDE EN L K F Q GPA I VF E S QDT AVE G IL A GK V KAG E VVVIRY 480
Cdd:COG0129 358 -- DR DQDV IR PLD N PY S PT GGLA I L R GN L A P DG AV VKTAGVDE SM L V F E GPA R VF D S EEE AVE A IL G GK I KAG D VVVIRY 435
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 481 EGPKGGPGM Q EML Y PT TY LK S MGLGKS C AL L TDGRFSGGT S GLSIGH A SPEAA S GG V I G LV NT GDIITIDIP S R SIT L D V 560
Cdd:COG0129 436 EGPKGGPGM R EML S PT SA LK G MGLGKS V AL I TDGRFSGGT R GLSIGH V SPEAA E GG P I A LV ED GDIITIDIP A R TLD L L V 515
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 1040425478 561 PEA EL TA RR EK qdalg WKP e NRQ R EV S FA L KA YA SMAT SA D KGAV R D KS 609
Cdd:COG0129 516 SDE EL AR RR AA ----- WKP - PEP R VT S GV L AK YA KLVS SA S KGAV T D PP 558
ilvD
TIGR00110 dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth ...
24-607
0e+00
dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth step in valine and isoleucine biosynthesis. It contains a catalytically essential [4Fe-4S] cluster This model generates scores of up to 150 bits vs. 6-phosphogluconate dehydratase, a homologous enzyme. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272910
Cd Length: 535
Bit Score: 848.62
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 24 ATG VK D D DFGKP I I A V V NS F T QF VPGH V HL K D MG Q L V AGE IE K AGG I A K EFNTIAV D DGIAMGH G GM L YSLPSRE L IADS 103
Cdd:TIGR00110 1 ATG FT D E DFGKP F I G V A NS Y T TI VPGH M HL R D LA Q A V KEG IE A AGG V A F EFNTIAV C DGIAMGH E GM K YSLPSRE I IADS 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 104 VE Y MVNAH CA D AM VCI SN CDKITPGM M MAA M RLNIP V IFV S GGPM EA G K TKL SDQ I IKLDLVD A MIQG A DPT IS D E QS E Q 183
Cdd:TIGR00110 81 VE T MVNAH RF D GL VCI PS CDKITPGM L MAA A RLNIP S IFV T GGPM LP G H TKL GKK I DLVSAFE A VGEY A AGK IS E E EL E E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 184 V ERSACP T CGSCSGMFTAN S M N CLTEALGLS Q PG NGS MLAT H A DREELFI N A GKRIV D L T K RYYE qddesal PR N I ANRA 263
Cdd:TIGR00110 161 I ERSACP G CGSCSGMFTAN T M A CLTEALGLS L PG CST MLAT S A EKKRIAK N S GKRIV E L V K KNIK ------- PR D I LTKE 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 264 AF D NA MAL D I A M GGS S NTVLHLLA A A Q E GDI D FDM DD I D AM SR R VPH LCKV APS T p KY H MED V HRAGG VM A I L G ELDR A G 343
Cdd:TIGR00110 234 AF E NA ITV D M A L GGS T NTVLHLLA I A N E AGV D LSL DD F D RL SR K VPH IASL APS G - KY V MED L HRAGG IP A V L K ELDR E G 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 344 LL NNQ T R TV L G LSMQ E Q L A Q YDIMQTEDE avlkffragpagirttkafsqdcrwdrldddrkeg C IR TKE N AFS QEGGLA 423
Cdd:TIGR00110 313 LL HGD T L TV T G KTLG E I L E Q APVIPEGQD ----------------------------------- V IR PLD N PVH QEGGLA 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 424 V L S GN I A VD G CI VK T AGVDE ENL KF Q GPA I VFES QDT A V E G IL A GK V K A G E VVVIRYEGPKGGPGM Q EML Y PT TYL K S MG 503
Cdd:TIGR00110 358 I L K GN L A PN G AV VK I AGVDE DMT KF E GPA K VFES EEE A L E A IL G GK I K E G D VVVIRYEGPKGGPGM P EML A PT SAI K G MG 437
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 504 LGKS C AL L TDGRFSGGT S GL S IGH A SPEAA S GG V I G LV NT GDII T IDIP S R SIT L D V PEA EL TA RR EKQD A LGW kpenrq 583
Cdd:TIGR00110 438 LGKS V AL I TDGRFSGGT R GL C IGH V SPEAA E GG P I A LV ED GDII I IDIP N R KLD L Q V SDE EL AE RR ASWK A PEP ------ 511
570 580
....*....|....*....|....
gi 1040425478 584 R E V SFA L KA YA SMAT SAD K GAV R D 607
Cdd:TIGR00110 512 R Y V KGY L AK YA KLVS SAD E GAV L D 535
ILVD_EDD
pfam00920 Dehydratase family;
34-604
0e+00
Dehydratase family;
Pssm-ID: 459998
Cd Length: 513
Bit Score: 808.09
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 34 KPII AVV NS FTQF VP G HVHL KDMGQL V AGEIEK AGG IAK EFNTI A V D DGIAMGH G GM L YSLPSRELIADS V E Y M VN AH CA 113
Cdd:pfam00920 1 KPII GIA NS YSDL VP C HVHL RELAEA V KEGVRE AGG VPA EFNTI G V C DGIAMGH E GM R YSLPSRELIADS I E E M LR AH PF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 114 D AM V C I SN CDKI T PGM M MAA M RLNIP V IFVSGGPM EA G KT klsdqii KL D LVD A MIQG A DPT IS D E QSEQV ER S ACP T CG 193
Cdd:pfam00920 81 D GL V L I GG CDKI V PGM L MAA A RLNIP A IFVSGGPM LP G GS ------- GT D EFE A VGAY A AGK IS E E ELLEI ER A ACP G CG 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 194 SC S GM F TAN S M N CL T EALGLS Q PG NGSML A TH A D R EE L FIN AG K RIV D L TK ryyeqdd E SAL PR N I AN R A AF D NA MAL D I 273
Cdd:pfam00920 154 SC G GM G TAN T M A CL A EALGLS L PG SATIP A VS A E R LR L ARE AG R RIV E L VE ------- E DIK PR D I LT R K AF E NA IVV D M 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 274 A M GGS S N T VLHLLA A A Q E GDI D FDM DD I D AM SR R VP H L CKVA PS t P KY H MED V HRAGGV M A I L G EL DR A g LL NNQTR TV L 353
Cdd:pfam00920 227 A L GGS T N A VLHLLA I A R E AGV D LTL DD F D RI SR K VP L L ADLK PS - G KY L MED F HRAGGV P A V L K EL LD A - LL HGDVL TV T 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 354 G LSMQ E Q LA Q ydimqtedeavlkffragpagirttkafsqdcrwdrl DDD R KEGC IR TKE N AF S QE GGLAVL S GN I A V DG 433
Cdd:pfam00920 305 G KTLG E N LA D ------------------------------------- AEV R DQDV IR PLD N PI S PT GGLAVL K GN L A P DG 347
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 434 CI VKT AG VD E E N L K F Q GPA I VF E S QDT A VEG IL A GK V KAG E VVVIRYEGPKGGPGM Q EML Y PT TY L KSM GLGK SC AL L TD 513
Cdd:pfam00920 348 AV VKT SA VD P E M L V F E GPA R VF D S EED A LAA IL D GK I KAG D VVVIRYEGPKGGPGM P EML T PT SA L LGA GLGK DV AL I TD 427
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 514 GRFSG GTS G L SIGH A SPEAA S GG V I G LV NT GDII T IDIP S R SIT L D V PEA EL T ARR EK qdalg WKP ENRQREVSFA L KA Y 593
Cdd:pfam00920 428 GRFSG ASR G P SIGH V SPEAA V GG P I A LV RD GDII R IDIP N R TLD L L V SDE EL A ARR AA ----- WKP PEPKVKGRGY L AK Y 502
570
....*....|.
gi 1040425478 594 A SMAT SA DK GA 604
Cdd:pfam00920 503 A KLVS SA SE GA 513
Name
Accession
Description
Interval
E-value
PRK12448
PRK12448 dihydroxy-acid dehydratase; Provisional
2-613
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237104
Cd Length: 615
Bit Score: 1366.07
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 2 P I YRS A TTTHGRNMAGARALWRATG V KD D DFGKPIIAVVNSFTQFVPGHVHLKD M GQLVA G EIE K AGG I AKEFNTIAVDD 81
Cdd:PRK12448 1 P K YRS R TTTHGRNMAGARALWRATG M KD E DFGKPIIAVVNSFTQFVPGHVHLKD L GQLVA R EIE A AGG V AKEFNTIAVDD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 82 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM M MAA M RLNIPV I FVSGGPMEAGKTKLSD Q IIK 161
Cdd:PRK12448 81 GIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGM L MAA L RLNIPV V FVSGGPMEAGKTKLSD K IIK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 162 LDLVDAM IQG ADP TI SDE QSE Q V ERSACPTCGSCSGMFTANSMNCLTEALGLS Q PGNGS M LATHADR EE LF IN AG K RIV D 241
Cdd:PRK12448 161 LDLVDAM VAA ADP SV SDE DVA Q I ERSACPTCGSCSGMFTANSMNCLTEALGLS L PGNGS L LATHADR KQ LF LE AG R RIV E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 242 L T KRYYEQDDES A LPR N IA NR AAF D NAM A LDIAMGGS S NTVLHLLAAAQE GDI DF D M D DID AM SR R VP H LCKVAP S T P KY 321
Cdd:PRK12448 241 L A KRYYEQDDES V LPR S IA TK AAF E NAM T LDIAMGGS T NTVLHLLAAAQE AEV DF T M A DID RL SR K VP C LCKVAP N T Q KY 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 322 HMEDVHRAGG V M A ILGELDRAGLL NNQTR TV L GL SMQ E Q L A Q Y DIM Q T E DEAV LK FFRA G P A GIRTT K AFSQDCRWD R LD 401
Cdd:PRK12448 321 HMEDVHRAGG I M G ILGELDRAGLL HTDVP TV H GL TLG E A L D Q W DIM R T Q DEAV KE FFRA A P G GIRTT V AFSQDCRWD S LD 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 402 D DR KE GCIR TK E N A F S QE GGLAVL S GNIA V DGCIVKTAGVDE EN LKF Q GPA I VFESQD T AVE G IL A GKVKAG E VVVIRYE 481
Cdd:PRK12448 401 T DR EN GCIR SV E H A Y S KD GGLAVL Y GNIA E DGCIVKTAGVDE SI LKF T GPA R VFESQD D AVE A IL G GKVKAG D VVVIRYE 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 482 GPKGGPGMQEMLYPT T YLKS M GLGK S CAL L TDGRFSGGTSGLSIGH A SPEAASGG V IGLV NT GDII T IDIP S RSI T L D V P 561
Cdd:PRK12448 481 GPKGGPGMQEMLYPT S YLKS K GLGK A CAL I TDGRFSGGTSGLSIGH V SPEAASGG A IGLV ED GDII E IDIP N RSI N L L V S 560
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 1040425478 562 EA EL T ARR EK Q D A L G --- WKP E NR Q R E VSFALKAYA SM ATSADKGAVRDKSKL E G 613
Cdd:PRK12448 561 DE EL A ARR AA Q E A R G dka WKP K NR E R K VSFALKAYA AL ATSADKGAVRDKSKL G G 615
IlvD
COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, ...
1-609
0e+00
Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; Dihydroxyacid dehydratase/phosphogluconate dehydratase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439899
Cd Length: 558
Bit Score: 972.18
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 1 MP IY RS A T T T H GR NM A G ARAL W RATG VK D D DFGKPII AVV NS FTQF VPGHVHL K D MGQL V AGE I EK AGG IAK EFNTIAV D 80
Cdd:COG0129 1 MP KM RS D T V T K GR ER A P ARAL L RATG LT D E DFGKPII GIA NS WNEI VPGHVHL D D LAEA V KEG I RA AGG VPF EFNTIAV S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 81 DGIAMGH G GM L YSLPSRELIADS V E Y MVNAHC A D AM VCI SN CDKITPGM M MAA M RLNIP V IFV S GGPM EA GK TK l SDQII 160
Cdd:COG0129 81 DGIAMGH E GM R YSLPSRELIADS I E T MVNAHC F D GL VCI PG CDKITPGM L MAA A RLNIP S IFV Y GGPM LP GK YD - GKDLD 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 161 KL D LVD A MIQG A DPT ISDE QSEQV ER S ACP T CGSCSGMFTAN S M N CLTEALGLS Q PG N G SML A TH A D R EE L FIN AG K RIV 240
Cdd:COG0129 160 IV D VFE A VGAY A AGK ISDE ELKEI ER N ACP G CGSCSGMFTAN T M A CLTEALGLS L PG S G TIP A VS A E R RR L ARE AG R RIV 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 241 D L TKR yyeqdde SAL PR N I AN R A AF D NA M A L D I A M GGS S NTVLHLLA A A Q E GDI D FDM DD I D AM SRR V PHLC KVA PS T p K 320
Cdd:COG0129 240 E L VEK ------- DIK PR D I LT R E AF E NA I A V D M A L GGS T NTVLHLLA I A H E AGV D LTL DD F D RI SRR T PHLC DLK PS G - K 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 321 YHMED V HRAGG VM A ILG EL DR AGLL NNQTR TV L G LSMQ E Q LA QY DI mqtedeavlkffragpagirttkafsqdcrwdrl 400
Cdd:COG0129 312 YHMED L HRAGG IP A VMK EL LD AGLL HGDCL TV T G KTLA E N LA DA DI ---------------------------------- 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 401 dd DR KEGC IR TKE N AF S QE GGLA V L S GN I A V DG CI VKTAGVDE EN L K F Q GPA I VF E S QDT AVE G IL A GK V KAG E VVVIRY 480
Cdd:COG0129 358 -- DR DQDV IR PLD N PY S PT GGLA I L R GN L A P DG AV VKTAGVDE SM L V F E GPA R VF D S EEE AVE A IL G GK I KAG D VVVIRY 435
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 481 EGPKGGPGM Q EML Y PT TY LK S MGLGKS C AL L TDGRFSGGT S GLSIGH A SPEAA S GG V I G LV NT GDIITIDIP S R SIT L D V 560
Cdd:COG0129 436 EGPKGGPGM R EML S PT SA LK G MGLGKS V AL I TDGRFSGGT R GLSIGH V SPEAA E GG P I A LV ED GDIITIDIP A R TLD L L V 515
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 1040425478 561 PEA EL TA RR EK qdalg WKP e NRQ R EV S FA L KA YA SMAT SA D KGAV R D KS 609
Cdd:COG0129 516 SDE EL AR RR AA ----- WKP - PEP R VT S GV L AK YA KLVS SA S KGAV T D PP 558
ilvD
TIGR00110 dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth ...
24-607
0e+00
dihydroxy-acid dehydratase; This protein, dihydroxy-acid dehydratase, catalyzes the fourth step in valine and isoleucine biosynthesis. It contains a catalytically essential [4Fe-4S] cluster This model generates scores of up to 150 bits vs. 6-phosphogluconate dehydratase, a homologous enzyme. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272910
Cd Length: 535
Bit Score: 848.62
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 24 ATG VK D D DFGKP I I A V V NS F T QF VPGH V HL K D MG Q L V AGE IE K AGG I A K EFNTIAV D DGIAMGH G GM L YSLPSRE L IADS 103
Cdd:TIGR00110 1 ATG FT D E DFGKP F I G V A NS Y T TI VPGH M HL R D LA Q A V KEG IE A AGG V A F EFNTIAV C DGIAMGH E GM K YSLPSRE I IADS 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 104 VE Y MVNAH CA D AM VCI SN CDKITPGM M MAA M RLNIP V IFV S GGPM EA G K TKL SDQ I IKLDLVD A MIQG A DPT IS D E QS E Q 183
Cdd:TIGR00110 81 VE T MVNAH RF D GL VCI PS CDKITPGM L MAA A RLNIP S IFV T GGPM LP G H TKL GKK I DLVSAFE A VGEY A AGK IS E E EL E E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 184 V ERSACP T CGSCSGMFTAN S M N CLTEALGLS Q PG NGS MLAT H A DREELFI N A GKRIV D L T K RYYE qddesal PR N I ANRA 263
Cdd:TIGR00110 161 I ERSACP G CGSCSGMFTAN T M A CLTEALGLS L PG CST MLAT S A EKKRIAK N S GKRIV E L V K KNIK ------- PR D I LTKE 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 264 AF D NA MAL D I A M GGS S NTVLHLLA A A Q E GDI D FDM DD I D AM SR R VPH LCKV APS T p KY H MED V HRAGG VM A I L G ELDR A G 343
Cdd:TIGR00110 234 AF E NA ITV D M A L GGS T NTVLHLLA I A N E AGV D LSL DD F D RL SR K VPH IASL APS G - KY V MED L HRAGG IP A V L K ELDR E G 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 344 LL NNQ T R TV L G LSMQ E Q L A Q YDIMQTEDE avlkffragpagirttkafsqdcrwdrldddrkeg C IR TKE N AFS QEGGLA 423
Cdd:TIGR00110 313 LL HGD T L TV T G KTLG E I L E Q APVIPEGQD ----------------------------------- V IR PLD N PVH QEGGLA 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 424 V L S GN I A VD G CI VK T AGVDE ENL KF Q GPA I VFES QDT A V E G IL A GK V K A G E VVVIRYEGPKGGPGM Q EML Y PT TYL K S MG 503
Cdd:TIGR00110 358 I L K GN L A PN G AV VK I AGVDE DMT KF E GPA K VFES EEE A L E A IL G GK I K E G D VVVIRYEGPKGGPGM P EML A PT SAI K G MG 437
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 504 LGKS C AL L TDGRFSGGT S GL S IGH A SPEAA S GG V I G LV NT GDII T IDIP S R SIT L D V PEA EL TA RR EKQD A LGW kpenrq 583
Cdd:TIGR00110 438 LGKS V AL I TDGRFSGGT R GL C IGH V SPEAA E GG P I A LV ED GDII I IDIP N R KLD L Q V SDE EL AE RR ASWK A PEP ------ 511
570 580
....*....|....*....|....
gi 1040425478 584 R E V SFA L KA YA SMAT SAD K GAV R D 607
Cdd:TIGR00110 512 R Y V KGY L AK YA KLVS SAD E GAV L D 535
ILVD_EDD
pfam00920 Dehydratase family;
34-604
0e+00
Dehydratase family;
Pssm-ID: 459998
Cd Length: 513
Bit Score: 808.09
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 34 KPII AVV NS FTQF VP G HVHL KDMGQL V AGEIEK AGG IAK EFNTI A V D DGIAMGH G GM L YSLPSRELIADS V E Y M VN AH CA 113
Cdd:pfam00920 1 KPII GIA NS YSDL VP C HVHL RELAEA V KEGVRE AGG VPA EFNTI G V C DGIAMGH E GM R YSLPSRELIADS I E E M LR AH PF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 114 D AM V C I SN CDKI T PGM M MAA M RLNIP V IFVSGGPM EA G KT klsdqii KL D LVD A MIQG A DPT IS D E QSEQV ER S ACP T CG 193
Cdd:pfam00920 81 D GL V L I GG CDKI V PGM L MAA A RLNIP A IFVSGGPM LP G GS ------- GT D EFE A VGAY A AGK IS E E ELLEI ER A ACP G CG 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 194 SC S GM F TAN S M N CL T EALGLS Q PG NGSML A TH A D R EE L FIN AG K RIV D L TK ryyeqdd E SAL PR N I AN R A AF D NA MAL D I 273
Cdd:pfam00920 154 SC G GM G TAN T M A CL A EALGLS L PG SATIP A VS A E R LR L ARE AG R RIV E L VE ------- E DIK PR D I LT R K AF E NA IVV D M 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 274 A M GGS S N T VLHLLA A A Q E GDI D FDM DD I D AM SR R VP H L CKVA PS t P KY H MED V HRAGGV M A I L G EL DR A g LL NNQTR TV L 353
Cdd:pfam00920 227 A L GGS T N A VLHLLA I A R E AGV D LTL DD F D RI SR K VP L L ADLK PS - G KY L MED F HRAGGV P A V L K EL LD A - LL HGDVL TV T 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 354 G LSMQ E Q LA Q ydimqtedeavlkffragpagirttkafsqdcrwdrl DDD R KEGC IR TKE N AF S QE GGLAVL S GN I A V DG 433
Cdd:pfam00920 305 G KTLG E N LA D ------------------------------------- AEV R DQDV IR PLD N PI S PT GGLAVL K GN L A P DG 347
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 434 CI VKT AG VD E E N L K F Q GPA I VF E S QDT A VEG IL A GK V KAG E VVVIRYEGPKGGPGM Q EML Y PT TY L KSM GLGK SC AL L TD 513
Cdd:pfam00920 348 AV VKT SA VD P E M L V F E GPA R VF D S EED A LAA IL D GK I KAG D VVVIRYEGPKGGPGM P EML T PT SA L LGA GLGK DV AL I TD 427
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 514 GRFSG GTS G L SIGH A SPEAA S GG V I G LV NT GDII T IDIP S R SIT L D V PEA EL T ARR EK qdalg WKP ENRQREVSFA L KA Y 593
Cdd:pfam00920 428 GRFSG ASR G P SIGH V SPEAA V GG P I A LV RD GDII R IDIP N R TLD L L V SDE EL A ARR AA ----- WKP PEPKVKGRGY L AK Y 502
570
....*....|.
gi 1040425478 594 A SMAT SA DK GA 604
Cdd:pfam00920 503 A KLVS SA SE GA 513
PRK00911
PRK00911 dihydroxy-acid dehydratase; Provisional
5-608
0e+00
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 234861
Cd Length: 552
Bit Score: 753.43
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 5 RS ATT T H G RNM A GA R ALW RATG VK D D DF G KP I I AVV NS FTQFV P GHV HL KDMGQL V AGEIEK AGG IAK EFNTI A V D DGIA 84
Cdd:PRK00911 2 RS DMI T K G VER A PH R SML RATG LT D E DF D KP F I GIA NS WNEIT P CNI HL NELADA V KEGVRA AGG VPF EFNTI G V S DGIA 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 85 MGH G GM L YSL P SRE L IADS V E YM VNAH CA D AM V C I SN CDK IT PGM M MAA M RLN I P V IFV S GGP MEA G kt K L SDQ ii K L D L 164
Cdd:PRK00911 82 MGH E GM K YSL V SRE V IADS I E TV VNAH WF D GL V A I PG CDK NM PGM L MAA A RLN V P S IFV Y GGP ILP G -- R L KGK -- D L T L 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 165 V D --- A MIQG A DPT IS D E QSEQV ER S ACP TC GSC S GMFTAN S M N CL T EALG L S Q PG N G SML A TH A D R E EL FIN AG KRI V D 241
Cdd:PRK00911 158 V S vfe A VGAY A AGK IS E E ELKEI ER N ACP GA GSC G GMFTAN T M A CL I EALG M S L PG S G TIP A VD A E R D EL ARE AG EAV V E 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 242 L TKRYY eqddesa L PR N I AN R A AF D NA M A L D I A M GGS S N T VLHLLA A A Q E GDI D FDM DD IDAM S R R V PHL CKVA PS T p KY 321
Cdd:PRK00911 238 L LEKDI ------- K PR D I LT R E AF E NA I A V D M A L GGS T N A VLHLLA I A H E AGV D LTL DD FNRI S K R T PHL ADLK PS G - KY 309
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 322 H MED V H R AGG VM A ILG EL DR AGLL NNQTR TV L G LSMQ E Q LA QYDI mqt E D EA V lkffragpagirttkafsqdcrwdrld 401
Cdd:PRK00911 310 V MED L H E AGG IP A VMK EL LD AGLL HGDCL TV T G KTLA E N LA DAPD --- P D QD V --------------------------- 359
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 402 ddrkegc IR TKE N AF S QE GGLA V L S GN I A VD G CI VK T AGV DE E nl K F Q GPA I VF E S QDT A V E G ILAGK V KAG E VVVIRYE 481
Cdd:PRK00911 360 ------- IR PLD N PI S PT GGLA I L K GN L A PE G AV VK I AGV KP E -- M F T GPA R VF D S EEE A M E A ILAGK I KAG D VVVIRYE 430
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 482 GPKGGPGM Q EML Y PT TYLKSM GLG KSC AL L TDGRFSGGT S GL SI GH A SPEAA S GG V I G LV NT GDIITID I P S R SITLD V P 561
Cdd:PRK00911 431 GPKGGPGM R EML A PT SAIVGA GLG DDV AL I TDGRFSGGT R GL CV GH V SPEAA V GG P I A LV ED GDIITID A P N R TLDVL V S 510
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1040425478 562 EA EL TA RR EK qdalg WKP e NRQREVSFA L KA YA SMAT SA DK GAV R D K 608
Cdd:PRK00911 511 DE EL AR RR AA ----- WKP - PEPKYKRGV L AK YA KLVS SA ST GAV T D P 551
PRK06131
PRK06131 dihydroxy-acid dehydratase; Validated
5-607
7.10e-110
dihydroxy-acid dehydratase; Validated
Pssm-ID: 235708
Cd Length: 571
Bit Score: 341.39
E-value: 7.10e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 5 RS ATT -- THGRNMAGA R ALWRAT G VK D DD F - G K PII AVV N SFTQFV P GHV H LKDMGQL V AGEIEK AGG IAK EF NT I AV dd 81
Cdd:PRK06131 6 RS LAW fg DDDFRAFYH R SFMKNQ G YP D EL F d G R PII GIC N TWSDLN P CNA H FRQLAER V KRGVLE AGG FPV EF PV I SL -- 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 82 giam G HGG ----- MLY slps R E L I A DS VE Y M VNAHCA D AM V CISN CDK I TP GMM M A A MRLNI P V I FV SGGPM EA GK T K LS 156
Cdd:PRK06131 84 ---- G ESF lrpta MLY ---- R N L A A MD VE E M IRGYPI D GV V LLGG CDK T TP ALL M G A ASVDL P A I VL SGGPM LN GK H K GE 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 157 D ----- QII K L - DLVD A miq G adp T I SD E QSEQV E RSACPTC G S C SG M F TA NS M N C LT EALG L S Q PGN GSML A TH A D R EE 230
Cdd:PRK06131 156 R lgsgt DVW K Y w EELR A --- G --- E I DL E EFLEA E AGMARSA G T C NT M G TA ST M A C MA EALG M S L PGN AAIP A VD A R R IR 229
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 231 LFINA G K RIV DLTK ryyeqdd E SAL P RN I AN R A AF D NA MALDI A M GGS S N T V L HL L A A A QEGDIDF D M DD I D AMS R R VP H 310
Cdd:PRK06131 230 MAELT G R RIV EMVH ------- E DLK P SD I LT R E AF E NA IRVNA A I GGS T N A V I HL I A I A GRAGVEL D L DD W D RIG R D VP V 302
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 311 L CKVA PS T p K Y H MED VHR AGG VM A I L G EL dr AG LL NNQTR TV L G LSMQ E Q LA Q ydi MQTEDEA V lkffragpagirttka 390
Cdd:PRK06131 303 L VNLQ PS G - E Y L MED FYY AGG LP A V L R EL -- GE LL HLDAL TV N G KTLG E N LA G --- APVYNDD V ---------------- 360
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 391 fsqdcrwdrldddrkegc IR TKE N AFSQ EGG L AVL S GN I A V DG CIV K TAGVDE E N LK FQ G P A I VFE SQDTAVEG I ---- L 466
Cdd:PRK06131 361 ------------------ IR PLD N PLKP EGG I AVL R GN L A P DG AVI K PSAASP E L LK HE G R A V VFE GYEDYKAR I ddpd L 422
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 467 A gk V KAGE V V V I R YE GPKG G PGM Q E -- MLYPTTY L KSM G L g K SCALLT D G R F SG GTS G LSIG H AS PEAA S GG VIG LV N TG 544
Cdd:PRK06131 423 D -- V DEDT V L V L R NA GPKG Y PGM P E vg NMPIPKK L LRQ G V - K DMVRIS D A R M SG TAY G TVVL H VA PEAA A GG PLA LV R TG 499
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1040425478 545 D I I TI D I P S R SIT L D V PEA EL TA RR EK qdalg W K P ENRQR E VSFA l KA Y ASMATS AD K G AVR D 607
Cdd:PRK06131 500 D R I RL D V P A R RLD L L V SDE EL AR RR AA ----- W P P PPPRA E RGYQ - EL Y RDHVLQ AD E G CDF D 556
PRK13016
PRK13016 dihydroxy-acid dehydratase; Provisional
26-604
6.37e-98
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237271
Cd Length: 577
Bit Score: 310.50
E-value: 6.37e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 26 G VKDD DF - GKP I IA VV N SFTQFV P G H V H LKDMGQL V AGEIEK AGG IAK E FNTIAVDDGI a MGHGG MLY slps R E L I A DSV 104
Cdd:PRK13016 33 G YAPE DF d GKP V IA IL N TWSDAN P C H G H FRERVED V KRGVLQ AGG FPL E LPALSLSENF - VKPTT MLY ---- R N L L A MET 107
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 105 E YMVNA H CA D AM V CISN CDK I TPG MM M A A MRLNI P V I FVSG GPM ---- EA GK T -- KL SD QIIKL D LVD A miqgad PT I SD 178
Cdd:PRK13016 108 E ELIRS H PV D GA V LMGG CDK T TPG LV M G A ISMGL P M I YLPA GPM lrgn YR GK V lg SG SD AWKYW D ERR A ------ GN I TQ 181
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 179 EQSEQV E RSACPTC G S C SG M F TA NS M NCLT EALGL SQ PG NG S ML A TH A DREELFINA G K RIV DLTK ryyeqdd E SAL P RN 258
Cdd:PRK13016 182 AEWLEI E GGIARSY G T C MT M G TA ST M TAIA EALGL TL PG AS S IP A AD A NHQRMAALC G R RIV EMVW ------- E DLT P SQ 254
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 259 I ANR AAF D NA MALDI A M G G S S N T V L HL L A A A QEGDIDFDM DD I D AMS R R VP HLCKVA PS TPK Y H MED VHR AGG VM A ILGE 338
Cdd:PRK13016 255 I LTK AAF E NA ITVAM A T G C S T N A V I HL I A M A RRAGVPLSL DD L D RCG R T VP VIANIR PS GKT Y L MED FFY AGG LR A LMKQ 334
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 339 L dr AGL L NNQTR TV L G LSMQEQ L AQYDIM qtedeavlkffragpagirttkafsqdcrwdrl D DD rkeg C IR TKE N AFSQ 418
Cdd:PRK13016 335 L -- GDK L HLDAL TV T G KTLGDN L EGAKVY --------------------------------- N DD ---- V IR PLD N PVYA 375
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 419 EG G LAVL S GN I A V DG CIV K T A GV D EEN L KFQ GPA I VF E S QDTAVEG I -- LAGK V KAGE V V V I R YE GP K GGPGM Q E -- ML - 493
Cdd:PRK13016 376 EG S LAVL R GN L A P DG AVI K P A AC D PKF L VHR GPA L VF D S YPEMKAA I dd ENLD V TPDH V M V L R NA GP Q GGPGM P E wg ML p 455
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 494 Y P TTY LK s M G L g KSCALLT D G R F SG GTS G LSIG H AS PEA AS GG VIG LV N TGDII TI D I P S R SIT L D V PEA EL TA RR EK qd 573
Cdd:PRK13016 456 I P KKL LK - Q G V - RDMVRIS D A R M SG TSY G ACVL H VA PEA YV GG PLA LV R TGDII EL D V P A R RLH L L V SDE EL AR RR AA -- 531
570 580 590
....*....|....*....|....*....|.
gi 1040425478 574 alg W K P EN R QR E VSFA l KAYASMATS ADKG A 604
Cdd:PRK13016 532 --- W Q P PE R RY E RGYG - WMFSQHVEQ ADKG C 558
PRK13017
PRK13017 dihydroxy-acid dehydratase; Provisional
33-607
9.17e-93
dihydroxy-acid dehydratase; Provisional
Pssm-ID: 237272
Cd Length: 596
Bit Score: 297.64
E-value: 9.17e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 33 GKPII AVVNSFTQFV P GHV H LKDMGQL V AGE I EK AGGI AK EF NTIAVDDG i AMGHGGM L Y slps R E L IADSVEYMVNAHC 112
Cdd:PRK13017 46 GKPII GIAQTGSDLS P CNR H HLELAER V KEG I RD AGGI PM EF PVHPIQET - GKRPTAA L D ---- R N L AYLGLVEILYGYP 120
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 113 A D AM V CISN CDK I TP GMM MAA MRLNI P V I FV SGGPM ---- EA G KTKL S DQI I kldl VD A MIQG A DPT I SD E QSEQVER S A 188
Cdd:PRK13017 121 L D GV V LTTG CDK T TP ACL MAA ATVDL P A I VL SGGPM ldgw HE G ERVG S GTV I ---- WK A RELL A AGE I DY E EFMELVA S S 196
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 189 C P TC G S C SG M F TA NS MN C L T EALG L S Q PG NGSML A THAD R EELFINA GKRIV DLTK ryyeqdd E SAL P RN I AN R A AF D NA 268
Cdd:PRK13017 197 A P SV G H C NT M G TA ST MN A L A EALG M S L PG CAAIP A PYRE R GQMAYAT GKRIV EMVW ------- E DLK P SD I LT R E AF E NA 269
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 269 MALDI A M GGS S N TVL HL L A A A QEGDIDFDM DD IDAMSRR VP H L CKVA P ST p KY HM ED V HRAGGV M A I L G EL D RAGLL NNQ 348
Cdd:PRK13017 270 IVVNS A I GGS T N API HL I A I A RHAGVELSL DD WQRVGED VP L L VNLQ P AG - KY LG ED F HRAGGV P A V L A EL L RAGLL HGD 348
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 349 TR TV L G LSMQ E QL A Q ydi MQTE D EA V lkffragpagirttkafsqdcrwdrldddrkegc IR TKENAFSQEG G LA VL S GN 428
Cdd:PRK13017 349 AL TV S G RTIG E NI A G --- APAP D RD V ---------------------------------- IR PYDAPLKERA G FL VL R GN 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 429 IA v D GC I V KT AGVD EE NLK ----------- F Q G P A I VF ESQDTAVEG I -- L A GKVKAGEVV VIR YE GP K G G PG MQ E -- ML 493
Cdd:PRK13017 392 LF - D SA I M KT SVIS EE FRE rylsepgdena F E G R A V VF DGPEDYHAR I dd P A LDIDEHCIL VIR GA GP V G Y PG SA E vv NM 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 494 Y P TTY L KSM G L g K S CALLT DGR F SG GTSGL SI GH ASPEAA S GG VIG L VN TGD I I T ID IPS R SITLD V PEA EL TA RR EK qd 573
Cdd:PRK13017 471 Q P PAA L LKR G I - R S LPCIG DGR Q SG TSGSP SI LN ASPEAA V GG GLA L LR TGD R I R ID LNK R RVDVL V SDE EL AR RR AA -- 547
570 580 590
....*....|....*....|....*....|....
gi 1040425478 574 alg W KP ENRQREVSFA l KA Y ASMATSADK GA VRD 607
Cdd:PRK13017 548 --- L KP PVPPSQTPWQ - EL Y RKHVGQLST GA CLE 577
yjhG_yagF
TIGR03432 putative dehydratase, YjhG/YagF family; This homolog of dihydroxy-acid dehydratases has an odd, ...
26-551
5.38e-55
putative dehydratase, YjhG/YagF family; This homolog of dihydroxy-acid dehydratases has an odd, sparse distribution. Members are found in two Acidobacteria, two Planctomycetes, Bacillus clausii KSM-K16, and (in two copies each) in strains K12-MG1655 and W3110 of Escherichia coli. The local context is not well conserved, but a few members are adjacent to homologs of the gluconate:H+ symporter (see TIGR00791). [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 163260
Cd Length: 640
Bit Score: 197.72
E-value: 5.38e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 26 G VKDD D f G K PI IAVVNS ftqfvp GH VHLKDMGQLV A G EI EKA G GIA ke F NTIAV D -- DG IAM G HG GM LY SLP S R ELI A DS 103
Cdd:TIGR03432 66 G LRAA D - G T PI ALGYHT ------ GH WEVGLLMKAA A E EI KRD G AVP -- F AGFVS D pc DG RTQ G TT GM FD SLP Y R NDA A MV 136
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 104 VEYMVNAH - CADAMVC I SN CDK IT P G MMMA - A MRLNI P VIF V S GG --- P M E A G KTKLSD Q I I kldlvdamiq GA DPTISD 178
Cdd:TIGR03432 137 MRRLIRSL p TRKGVIG I AT CDK GL P A MMMA l A ATHHL P TVL V P GG vtl P P E V G EDAGKV Q T I ---------- GA RFSNGE 206
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 179 EQS E QVERSA C PT C G S ---- C SGMF TA NSMNCLT EALGL SQ P GNGSMLATHADREELFINAGKRIVD L TKR yyeqdde SA 254
Cdd:TIGR03432 207 ITL E EAAEAG C RA C A S pggg C QFLG TA ATSQVVA EALGL AL P HSALAPSGQPIWLDMARRSARAALE L SQK ------- GL 279
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 255 LP R N I ANRA A FD NAM ALDI A M GGS S N TV LH LL A - A AQE G DIDFDM DD IDAMS R R VP H L CKVA P ST P KY H ME - D V HR AGGV 332
Cdd:TIGR03432 280 ST R D I LTDK A IE NAM VVHA A F GGS T N LL LH IP A i A HAA G CRRPTV DD WTRIN R K VP R L VDAL P NG P VG H PT v R V FL AGGV 359
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 333 MAILGE L D RAGLL NNQTR TV L G LSMQ E Q L AQYD im QT E DE A VL K ffragp AGI R TT kafsqdcrw D RL D - DD RKEGCIRT 411
Cdd:TIGR03432 360 PEVMLH L R RAGLL HEDVL TV T G ETLG E N L DWWE -- NS E RR A RM K ------ QRL R ER --------- D GV D p DD VIMSPAQA 422
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1040425478 412 K ENAFSQE gg LAVLS GN I A VD G CIV K TAGV D ------ EENLKFQ GPA I VF E S QDT A VEG I LA GK VK AG E V V V IRYE GP K G 485
Cdd:TIGR03432 423 K ARGLTST -- VTFPK GN L A PE G SVI K STAI D psvvde DGVYRHT GPA R VF S S EKS A IAA I KH GK IE AG D V L V LIGR GP S G 500
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1040425478 486 G p GM Q E MLYP T TY LK SMGL GK SC AL L TD G RFSG GTS G LS IGH AS PEA AS GG V IG L V NT GD I I T I D I 551
Cdd:TIGR03432 501 T - GM E E TYQV T SA LK YLSF GK HV AL I TD A RFSG VST G AC IGH VG PEA LA GG P IG K V RD GD L I E I I I 565
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
