|
Name |
Accession |
Description |
Interval |
E-value |
| ZnuA |
COG0803 |
ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA [Inorganic ion transport and ... |
1-307 |
5.66e-105 |
|
ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA [Inorganic ion transport and metabolism];
Pssm-ID: 440566 [Multi-domain] Cd Length: 286 Bit Score: 308.33 E-value: 5.66e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 1 MKKVILFLFTITLsVVLAACSNGDKDGDsdkelesvdkDKIKVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPK 80
Cdd:COG0803 1 MKRLLLALLLLAA-LLLAGCSAAASSAA----------GKLKVVATFSPLADLAKQIGGDKVEVTSLVPPGADPHDYEPT 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 81 PDDIKHISSADLVFYNGLNLEggskGWLFKALESSDFSKENAIKTSEGVKPKYIKDEDGKKEVNPHAFIDPKVGEKMIKN 160
Cdd:COG0803 70 PSDIAKLAKADLVVYNGLGLE----GWLDKLLEAAGNPGVPVVDASEGIDLLELEEGHDHGEPDPHVWLDPKNAKKVAEN 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 161 ITKSLSERNPKNKDYYKENEKAYLKKLHNIEDDYEKQLGDIPKkdRVFVASEQAFQYLTDRYDLKEGYIWAIDTDENGSP 240
Cdd:COG0803 146 IADALAELDPANAAYYEANAAAYLAELDALDAEIKAKLAAIPG--RKLVTSHDAFGYLARAYGLEVVAIQGISPGSEPSP 223
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080980409 241 EQIKDLVKFIDKNEPSHLFVESNVDKRPMETVSKESGVsiykKPIYSDEISKEGGVADTYLKYLEYN 307
Cdd:COG0803 224 ADLAELIDLIKEEGVKAIFVESQVSPKLAETLAEETGV----KVLYLDSLGGPGGPGDTYLDMMRHN 286
|
|
| PsaA |
cd01137 |
Metal binding protein PsaA. These proteins have been shown to function as initial receptors ... |
17-315 |
2.40e-101 |
|
Metal binding protein PsaA. These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).
Pssm-ID: 238557 [Multi-domain] Cd Length: 287 Bit Score: 299.19 E-value: 2.40e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 17 LAACSNGDKDgdsdkelESVDKDKIKVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYN 96
Cdd:cd01137 1 LAACASLGSS-------PATAASKLKVVATFSILADIARNIAGDRVNVTSIVPPGADPHEYEPTPSDIKKLSKADLILYN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 97 GLNLEGgskgWLFKALESSDFSKEnAIKTSEGVKPKYIKDEDGKKEVNPHAFIDPKVGEKMIKNITKSLSERNPKNKDYY 176
Cdd:cd01137 74 GLNLEP----WLERLVKNAGKDVP-VVAVSEGIDPIPLEEGHYKGKPDPHAWMSPKNAIIYVKNIAKALSEADPANAETY 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 177 KENEKAYLKKLHNIEDDYEKQLGDIPKKDRVFVASEQAFQYLTDRYDLKEGYIWAIDTDENGSPEQIKDLVKFIDKNEPS 256
Cdd:cd01137 149 QKNAAAYKAKLKALDEWAKAKFATIPAEKRKLVTSEGAFSYFAKAYGLKEAYLWPINTEEEGTPKQVATLIEQVKKEKVP 228
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1080980409 257 HLFVESNVDKRPMETVSKESGVSIYKKpIYSDEISKEGGVADTYLKYLEYNLDVLTDGL 315
Cdd:cd01137 229 AVFVESTVNDRLMKQVAKETGAKIGGQ-LYTDSLSEKGGPADTYLDMMEHNLDTIVEGL 286
|
|
| ZnuA |
pfam01297 |
Zinc-uptake complex component A periplasmic; ZnuA includes periplasmic solute binding proteins ... |
43-314 |
1.02e-92 |
|
Zinc-uptake complex component A periplasmic; ZnuA includes periplasmic solute binding proteins such as TroA that interacts with an ATP-binding cassette transport system in Treponema pallidum. ZnuA is part of the bacterial zinc-uptake complex ZnuABC, whose components are the following families, ZinT, pfam09223, pfam00950, pfam00005, all of which are regulated by the transcription-regulator family FUR, pfam01475. ZinT acts as a Zn2+-buffering protein that delivers Zn2+ to ZnuA (TroA), a high-affinity zinc-uptake protein. In Gram-negative bacteria the ZnuABC transporter system ensures an adequate import of zinc in Zn2+-poor environments, such as those encountered by pathogens within the infected host.
Pssm-ID: 460151 [Multi-domain] Cd Length: 269 Bit Score: 276.36 E-value: 1.02e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 43 VVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEGgskgWLFKALESSDfsKENA 122
Cdd:pfam01297 1 VVATTYPLADLAKQIGGDRVEVTSLVPPGADPHDYEPTPSDIAALSDADLVVYNGLGLEP----WLDKLLEALP--NKKV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 123 IKTSEGVKPKYIKDEDGKKE-----VNPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEKAYLKKLHNIEDDYEKQ 197
Cdd:pfam01297 75 VDASEGVELLDEEGEEEDHDghdhgYDPHVWLDPKNAKKMAENIADALSELDPANAATYEANAAAYLAELDALDAEIKEQ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 198 LGDIPKKDRVFVASEQAFQYLTDRYDLKEGYIWAIDTDENGSPEQIKDLVKFIDKNEPSHLFVESNVDKRPMETVSKESG 277
Cdd:pfam01297 155 LASIPEKTRKLVTSHDAFGYLARAYGLEQVGIQGVSPESEPSAADLAELIDLIKEKKVKAIFVEPQVSPKLAETVAKETG 234
|
250 260 270
....*....|....*....|....*....|....*..
gi 1080980409 278 VSIYkKPIYSDEISKEGGvADTYLKYLEYNLDVLTDG 314
Cdd:pfam01297 235 VKVL-GPLYTDSLGEPGG-GATYLDLMRHNLDTLAEA 269
|
|
| AztC |
NF040870 |
zinc ABC transporter substrate-binding protein AztC; |
43-315 |
6.45e-54 |
|
zinc ABC transporter substrate-binding protein AztC;
Pssm-ID: 468807 [Multi-domain] Cd Length: 277 Bit Score: 177.46 E-value: 6.45e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 43 VVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEGGskgwLFKALESSDFSKENA 122
Cdd:NF040870 1 VVVTTNILGDLARNVVGDRAEVTTLMKPDADPHSFEPSAADAAALERADLVVVNGLGLEEG----FLRHLIAASATGAPV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 123 IKTSEGVKP-KYIKDEDGKKEV-----NPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEKAYLKKLHNIEDDYEK 196
Cdd:NF040870 77 VEVGDGVDPlPYPEGGHYHFEAgagppDPHFWTDPARARDAVDNIADAFCEADDGDCAAYRANAAAYRAELDELDAEMRE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 197 QLGDIPKKDRVFVASEQAFQYLTDRYDLKegYIWAID----TDENGSPEQIKDLVKFIDKNEPSHLFVESNVDKRPMETV 272
Cdd:NF040870 157 AFAAIPADRRTLVTNHHVFGYLAERYGFR--VLGAVIpsgsTLASPSAADLASLARAIREAGVPAIFAESSQPPRLAEVL 234
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1080980409 273 SKESGVSIYKKPIYSDEISKEGGVADTYLKYLEYNLDVLTDGL 315
Cdd:NF040870 235 ASEAGLDVGVVELYSESLSEPDGGAATYLDMMRANAEAIVDGL 277
|
|
| znuA |
PRK09545 |
zinc ABC transporter substrate-binding protein ZnuA; |
43-225 |
6.81e-14 |
|
zinc ABC transporter substrate-binding protein ZnuA;
Pssm-ID: 236558 [Multi-domain] Cd Length: 311 Bit Score: 70.81 E-value: 6.81e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 43 VVTSF-------SMIDDMVKEiggehVEVknLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEggskGWLFKALESS 115
Cdd:PRK09545 27 VVTSIkplgfiaSAIADGVTE-----TEV--LLPDGASPHDYSLRPSDVKRLQSADLVVWVGPEME----AFLEKPVSKL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 116 DFSKENAIKTSEGVKPKYIKDEDGKK--------------------EVNPHAFIDPKVGEKMIKNITKSLSERNPKNKDY 175
Cdd:PRK09545 96 PENKQVTIAQLPDVKPLLMKGAHDDHhdddhdhagheksdedhhhgEYNMHIWLSPEIARATAVAIHDKLVELMPQSKAK 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1080980409 176 YKENEKAYLKKLHNIEDDYEKQLGdiPKKDRVFVASEQAFQYLTDRYDLK 225
Cdd:PRK09545 176 LDANLKDFEAQLAQTDKQIGNQLA--PVKGKGYFVFHDAYGYFEKHYGLT 223
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ZnuA |
COG0803 |
ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA [Inorganic ion transport and ... |
1-307 |
5.66e-105 |
|
ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA [Inorganic ion transport and metabolism];
Pssm-ID: 440566 [Multi-domain] Cd Length: 286 Bit Score: 308.33 E-value: 5.66e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 1 MKKVILFLFTITLsVVLAACSNGDKDGDsdkelesvdkDKIKVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPK 80
Cdd:COG0803 1 MKRLLLALLLLAA-LLLAGCSAAASSAA----------GKLKVVATFSPLADLAKQIGGDKVEVTSLVPPGADPHDYEPT 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 81 PDDIKHISSADLVFYNGLNLEggskGWLFKALESSDFSKENAIKTSEGVKPKYIKDEDGKKEVNPHAFIDPKVGEKMIKN 160
Cdd:COG0803 70 PSDIAKLAKADLVVYNGLGLE----GWLDKLLEAAGNPGVPVVDASEGIDLLELEEGHDHGEPDPHVWLDPKNAKKVAEN 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 161 ITKSLSERNPKNKDYYKENEKAYLKKLHNIEDDYEKQLGDIPKkdRVFVASEQAFQYLTDRYDLKEGYIWAIDTDENGSP 240
Cdd:COG0803 146 IADALAELDPANAAYYEANAAAYLAELDALDAEIKAKLAAIPG--RKLVTSHDAFGYLARAYGLEVVAIQGISPGSEPSP 223
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080980409 241 EQIKDLVKFIDKNEPSHLFVESNVDKRPMETVSKESGVsiykKPIYSDEISKEGGVADTYLKYLEYN 307
Cdd:COG0803 224 ADLAELIDLIKEEGVKAIFVESQVSPKLAETLAEETGV----KVLYLDSLGGPGGPGDTYLDMMRHN 286
|
|
| PsaA |
cd01137 |
Metal binding protein PsaA. These proteins have been shown to function as initial receptors ... |
17-315 |
2.40e-101 |
|
Metal binding protein PsaA. These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).
Pssm-ID: 238557 [Multi-domain] Cd Length: 287 Bit Score: 299.19 E-value: 2.40e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 17 LAACSNGDKDgdsdkelESVDKDKIKVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYN 96
Cdd:cd01137 1 LAACASLGSS-------PATAASKLKVVATFSILADIARNIAGDRVNVTSIVPPGADPHEYEPTPSDIKKLSKADLILYN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 97 GLNLEGgskgWLFKALESSDFSKEnAIKTSEGVKPKYIKDEDGKKEVNPHAFIDPKVGEKMIKNITKSLSERNPKNKDYY 176
Cdd:cd01137 74 GLNLEP----WLERLVKNAGKDVP-VVAVSEGIDPIPLEEGHYKGKPDPHAWMSPKNAIIYVKNIAKALSEADPANAETY 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 177 KENEKAYLKKLHNIEDDYEKQLGDIPKKDRVFVASEQAFQYLTDRYDLKEGYIWAIDTDENGSPEQIKDLVKFIDKNEPS 256
Cdd:cd01137 149 QKNAAAYKAKLKALDEWAKAKFATIPAEKRKLVTSEGAFSYFAKAYGLKEAYLWPINTEEEGTPKQVATLIEQVKKEKVP 228
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1080980409 257 HLFVESNVDKRPMETVSKESGVSIYKKpIYSDEISKEGGVADTYLKYLEYNLDVLTDGL 315
Cdd:cd01137 229 AVFVESTVNDRLMKQVAKETGAKIGGQ-LYTDSLSEKGGPADTYLDMMEHNLDTIVEGL 286
|
|
| ZnuA |
pfam01297 |
Zinc-uptake complex component A periplasmic; ZnuA includes periplasmic solute binding proteins ... |
43-314 |
1.02e-92 |
|
Zinc-uptake complex component A periplasmic; ZnuA includes periplasmic solute binding proteins such as TroA that interacts with an ATP-binding cassette transport system in Treponema pallidum. ZnuA is part of the bacterial zinc-uptake complex ZnuABC, whose components are the following families, ZinT, pfam09223, pfam00950, pfam00005, all of which are regulated by the transcription-regulator family FUR, pfam01475. ZinT acts as a Zn2+-buffering protein that delivers Zn2+ to ZnuA (TroA), a high-affinity zinc-uptake protein. In Gram-negative bacteria the ZnuABC transporter system ensures an adequate import of zinc in Zn2+-poor environments, such as those encountered by pathogens within the infected host.
Pssm-ID: 460151 [Multi-domain] Cd Length: 269 Bit Score: 276.36 E-value: 1.02e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 43 VVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEGgskgWLFKALESSDfsKENA 122
Cdd:pfam01297 1 VVATTYPLADLAKQIGGDRVEVTSLVPPGADPHDYEPTPSDIAALSDADLVVYNGLGLEP----WLDKLLEALP--NKKV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 123 IKTSEGVKPKYIKDEDGKKE-----VNPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEKAYLKKLHNIEDDYEKQ 197
Cdd:pfam01297 75 VDASEGVELLDEEGEEEDHDghdhgYDPHVWLDPKNAKKMAENIADALSELDPANAATYEANAAAYLAELDALDAEIKEQ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 198 LGDIPKKDRVFVASEQAFQYLTDRYDLKEGYIWAIDTDENGSPEQIKDLVKFIDKNEPSHLFVESNVDKRPMETVSKESG 277
Cdd:pfam01297 155 LASIPEKTRKLVTSHDAFGYLARAYGLEQVGIQGVSPESEPSAADLAELIDLIKEKKVKAIFVEPQVSPKLAETVAKETG 234
|
250 260 270
....*....|....*....|....*....|....*..
gi 1080980409 278 VSIYkKPIYSDEISKEGGvADTYLKYLEYNLDVLTDG 314
Cdd:pfam01297 235 VKVL-GPLYTDSLGEPGG-GATYLDLMRHNLDTLAEA 269
|
|
| AdcA |
cd01017 |
Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of ... |
38-315 |
2.20e-66 |
|
Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).
Pssm-ID: 238499 [Multi-domain] Cd Length: 282 Bit Score: 209.46 E-value: 2.20e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 38 KDKIKVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEggskGWLFKALESSDF 117
Cdd:cd01017 1 SGKLKVVTTFYPLYEFTKAIGGDKADVKLIIPAGTEPHDFEPSPKDIARIADADVFVYNGLGME----TWAEKVLKSLQN 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 118 SKENAIKTSEGVKP---------KYIKDEDGKKEVNPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEKAYLKKLH 188
Cdd:cd01017 77 KKLKVVEASKGIKLlkaggaehdHDHSHSHHHGDYDPHVWLSPVLAIQQVENIKDALIKLDPDNKEYYEKNAAAYAKKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 189 NIEDDYEKQLGDIPKKDrvFVASEQAFQYLTDRYDLKEGYIWAIDTDENGSPEQIKDLVKFIDKNEPSHLFVESNVDKRP 268
Cdd:cd01017 157 ALDQEYRAKLAKAKGKT--FVTQHAAFGYLARRYGLKQIAIVGVSPEVEPSPKQLAELVEFVKKSDVKYIFFEENASSKI 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1080980409 269 METVSKESGVSIYK-KPIYSDEiSKEGGVADTYLKYLEYNLDVLTDGL 315
Cdd:cd01017 235 AETLAKETGAKLLVlNPLETLT-KEEIDDGKDYFSLMKENLETLKRAL 281
|
|
| TroA |
cd01016 |
Metal binding protein TroA. These proteins have been shown to function as initial receptors in ... |
40-315 |
1.99e-55 |
|
Metal binding protein TroA. These proteins have been shown to function as initial receptors in ABC transport of Zn2+ and possibly Fe3+ in many eubacterial species. The TroA proteins belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).
Pssm-ID: 238498 [Multi-domain] Cd Length: 276 Bit Score: 181.41 E-value: 1.99e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 40 KIKVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEGgSKGWLFKALESSdfsk 119
Cdd:cd01016 1 KPNVVTTTGMIADAVENIGGDHVEVTGLMGPGVDPHLYKATAGDVEKLQNADVVFYNGLHLEG-KMSDVLSKLGSS---- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 120 ENAIKTSEGVKPKYIKDEDGKKEVNPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEKAYLKKLHNIEDDYEKQLG 199
Cdd:cd01016 76 KSVIALEDTLDRSQLILDEEEGTYDPHIWFDVKLWKYAVKAVAEVLSEKLPEHKDEFQANSEAYVEELDSLDAYAKKKIA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 200 DIPKKDRVFVASEQAFQYLTDRYDLKEGYIWAIDTDENGSPEQIKDLVKFIDKNEPSHLFVESNVDKRPMETV---SKES 276
Cdd:cd01016 156 EIPEQQRVLVTAHDAFGYFGRAYGFEVKGLQGISTDSEAGLRDINELVDLIVERKIKAIFVESSVNQKSIEALqdaVKAR 235
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1080980409 277 GVSI-YKKPIYSDEISKEGGVADTYLKYLEYNLDVLTDGL 315
Cdd:cd01016 236 GHDVqIGGELYSDAMGEEGTSEGTYIGMFKHNVDTIVEAL 275
|
|
| AztC |
NF040870 |
zinc ABC transporter substrate-binding protein AztC; |
43-315 |
6.45e-54 |
|
zinc ABC transporter substrate-binding protein AztC;
Pssm-ID: 468807 [Multi-domain] Cd Length: 277 Bit Score: 177.46 E-value: 6.45e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 43 VVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEGGskgwLFKALESSDFSKENA 122
Cdd:NF040870 1 VVVTTNILGDLARNVVGDRAEVTTLMKPDADPHSFEPSAADAAALERADLVVVNGLGLEEG----FLRHLIAASATGAPV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 123 IKTSEGVKP-KYIKDEDGKKEV-----NPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEKAYLKKLHNIEDDYEK 196
Cdd:NF040870 77 VEVGDGVDPlPYPEGGHYHFEAgagppDPHFWTDPARARDAVDNIADAFCEADDGDCAAYRANAAAYRAELDELDAEMRE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 197 QLGDIPKKDRVFVASEQAFQYLTDRYDLKegYIWAID----TDENGSPEQIKDLVKFIDKNEPSHLFVESNVDKRPMETV 272
Cdd:NF040870 157 AFAAIPADRRTLVTNHHVFGYLAERYGFR--VLGAVIpsgsTLASPSAADLASLARAIREAGVPAIFAESSQPPRLAEVL 234
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1080980409 273 SKESGVSIYKKPIYSDEISKEGGVADTYLKYLEYNLDVLTDGL 315
Cdd:NF040870 235 ASEAGLDVGVVELYSESLSEPDGGAATYLDMMRANAEAIVDGL 277
|
|
| ZnuA |
cd01019 |
Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in ... |
39-311 |
1.00e-36 |
|
Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a single helix and bind their specific ligands in the cleft between these domains. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).
Pssm-ID: 238501 [Multi-domain] Cd Length: 286 Bit Score: 132.88 E-value: 1.00e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 39 DKIKVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEggskGWLFKALESSDFS 118
Cdd:cd01019 2 AEASVLTSIKPLGFIAAAIMGGVGEVEVLVPPGASPHDYELRPSDARKLQEADLVVWIGPDLE----AFLDKVLQGRKKG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 119 KENAIKTSEGVKPKYIKDEDGKKEV-----------------NPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEK 181
Cdd:cd01019 78 KVLTLAKLIDLKTLEDGASHGDHEHdhehahgehdgheegglDPHLWLSPENAAEVAQAVAEKLSALDPDNAATYAANLE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 182 AYLKKLHNIEDDYEKQLGDIpkKDRVFVASEQAFQYLTDRYDLKEGYIWAIDTDENGSPEQIKDLVKFIDKNEPSHLFVE 261
Cdd:cd01019 158 AFNARLAELDATIKERLAPV--KTKPFFVFHDAYGYFEKRYGLTQAGVFTIDPEIDPGAKRLAKIRKEIKEKGATCVFAE 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1080980409 262 SNVDKRPMETVSKESGVsiyKKPIYSDEISKEGGVADTYLKYLEYNLDVL 311
Cdd:cd01019 236 PQFHPKIAETLAEGTGA---KVGELDPLGGLIELGKNSYVNFLRNLADSL 282
|
|
| TroA_b |
cd01020 |
Metal binding protein TroA_b. These proteins are predicted to function as initial receptors ... |
39-262 |
1.44e-32 |
|
Metal binding protein TroA_b. These proteins are predicted to function as initial receptors in ABC transport of metal ions. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).
Pssm-ID: 238502 [Multi-domain] Cd Length: 264 Bit Score: 121.39 E-value: 1.44e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 39 DKIKVVTSFSMIDDMVKEIGGEHVEVKNLV-PTGTDPHDYDPKPDDIKHISSADLVFYNGlnleGGSKGWLFKALESSDf 117
Cdd:cd01020 1 GKINVVASTNFWGSVAEAVGGDHVEVTSIItNPDVDPHDFEPTPTDAAKVSTADIVVYNG----GGYDPWMTKLLADTK- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 118 skeNAIKTSEGVKPKYIKDEDgkkevNPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEKAYLKKLhnieDDYEKQ 197
Cdd:cd01020 76 ---DVIVIAADLDGHDDKEGD-----NPHLWYDPETMSKVANALADALVKADPDNKKYYQANAKKFVASL----KPLAAK 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080980409 198 LGDIPKK--DRVFVASEQAFQYLTDRYDLKE----GYIWAIDTDENGSPEQIKDLVKFIDKNEPSHLFVES 262
Cdd:cd01020 144 IAELSAKykGAPVAATEPVFDYLLDALGMKErtpkGYTATTESETEPSPADIAAFQNAIKNRQIDALIVNP 214
|
|
| ZntC |
cd01018 |
Metal binding protein ZntC. These proteins are predicted to function as initial receptors in ... |
39-282 |
9.49e-31 |
|
Metal binding protein ZntC. These proteins are predicted to function as initial receptors in ABC transport of metal ions. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and bind their specific ligands in the cleft between these domains. In addition, many of these proteins possess a metal-binding histidine-rich motif (repetitive HDH sequence).
Pssm-ID: 238500 [Multi-domain] Cd Length: 266 Bit Score: 116.69 E-value: 9.49e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 39 DKIKVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLnleGGSKGWLFKALesSDFS 118
Cdd:cd01018 1 DKPTVAVSIEPQKYFVEKIAGDTVDVVVLVPPGSNPHTYEPKPQQMKKLSEADLYFRIGL---GFEEVWLERFR--SNNP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 119 KENAIKTSEGVKPKYIKDEDGKKEV----------NPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEKAYLKKLH 188
Cdd:cd01018 76 KMQVVNMSKGITLIPMADHHHHHHGehehhhhgnyDPHIWLSPANAKIMAENIYEALAELDPQNATYYQANLDALLAELD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 189 NIEDDYEKQLGdiPKKDRVFVASEQAFQYLTDRYDLKEgyiwaIDTDENG---SPEQIKDLVKFIDKNEPSHLFVESNVD 265
Cdd:cd01018 156 ALDSEIRTILS--KLKQRAFMVYHPAWGYFARDYGLTQ-----IPIEEEGkepSPADLKRLIDLAKEKGVRVVFVQPQFS 228
|
250
....*....|....*..
gi 1080980409 266 KRPMETVSKESGVSIYK 282
Cdd:cd01018 229 TKSAEAIAREIGAKVVT 245
|
|
| TroA_c |
cd01145 |
Periplasmic binding protein TroA_c. These proteins are predicted to function as initial ... |
43-225 |
1.56e-27 |
|
Periplasmic binding protein TroA_c. These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind their ligands in the cleft between these domains.
Pssm-ID: 238565 [Multi-domain] Cd Length: 203 Bit Score: 106.43 E-value: 1.56e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 43 VVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEggskGWLFKALE-SSDFSKEN 121
Cdd:cd01145 5 VVVTFPDLKDLVREVAGDAVIVSALTPPGVDPHQYQLKPSDIAKMRKADLVVTSGHELE----GFEPKLAElSSNSKVQP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 122 AIKTSEGVKPKYIKDE----DGKKEVNPHAFIDPKVGEKMIKNITKSLSERNPKNKDYYKENEKAYLKKLHNIEDDYEKQ 197
Cdd:cd01145 81 GIKILIEDSDTVGMVDramgDYHGKGNPHVWLDPNNAPALAKALADALIELDPSEQEEYKENLRVFLAKLNKLLREWERQ 160
|
170 180
....*....|....*....|....*...
gi 1080980409 198 LGdiPKKDRVFVASEQAFQYLTDRYDLK 225
Cdd:cd01145 161 FE--GLKGIQVVAYHPSYQYLADWLGIE 186
|
|
| ZnuA |
COG4531 |
ABC-type Zn2+ transport system, periplasmic component/surface adhesin ZnuA [Inorganic ion ... |
42-280 |
1.90e-23 |
|
ABC-type Zn2+ transport system, periplasmic component/surface adhesin ZnuA [Inorganic ion transport and metabolism];
Pssm-ID: 443599 [Multi-domain] Cd Length: 300 Bit Score: 97.59 E-value: 1.90e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 42 KVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEggskGWLFKALESSDFSKEN 121
Cdd:COG4531 11 RVVTSIKPLHSLVAAVMDGVGEPELLLPPGASPHDYALRPSDARALQDADLVFWVGPDLE----PFLEKPLETLAPDAKV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 122 -AIKTSEGVKPKYIK------------------------DEDGKKEVNPHAFIDPKVGEKMIKNITKSLSERNPKNKDYY 176
Cdd:COG4531 87 vELLELPGLTLLPFReggdfehhdhhdehhhhhhhhddhHDHHHGGYDPHLWLSPENAKAWAAAIADALSELDPENAATY 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 177 KENEKAYLKKLHNIEDDYEKQLGdiPKKDRVFVASEQAFQYLTDRYDLK-EGYIwAIDTDENGSPEQIKDLVKFIDKNEP 255
Cdd:COG4531 167 QANAAAFEARLDALDAEIAAQLA--PVKGKPFFVFHDAYQYFEKRFGLNaLGAI-TLNPEIQPGAKRLAEIREKLKELGA 243
|
250 260
....*....|....*....|....*
gi 1080980409 256 SHLFVESNVDKRPMETVSKESGVSI 280
Cdd:COG4531 244 VCVFAEPQFNPALVETVAEGTGVRT 268
|
|
| znuA |
PRK09545 |
zinc ABC transporter substrate-binding protein ZnuA; |
43-225 |
6.81e-14 |
|
zinc ABC transporter substrate-binding protein ZnuA;
Pssm-ID: 236558 [Multi-domain] Cd Length: 311 Bit Score: 70.81 E-value: 6.81e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 43 VVTSF-------SMIDDMVKEiggehVEVknLVPTGTDPHDYDPKPDDIKHISSADLVFYNGLNLEggskGWLFKALESS 115
Cdd:PRK09545 27 VVTSIkplgfiaSAIADGVTE-----TEV--LLPDGASPHDYSLRPSDVKRLQSADLVVWVGPEME----AFLEKPVSKL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 116 DFSKENAIKTSEGVKPKYIKDEDGKK--------------------EVNPHAFIDPKVGEKMIKNITKSLSERNPKNKDY 175
Cdd:PRK09545 96 PENKQVTIAQLPDVKPLLMKGAHDDHhdddhdhagheksdedhhhgEYNMHIWLSPEIARATAVAIHDKLVELMPQSKAK 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1080980409 176 YKENEKAYLKKLHNIEDDYEKQLGdiPKKDRVFVASEQAFQYLTDRYDLK 225
Cdd:PRK09545 176 LDANLKDFEAQLAQTDKQIGNQLA--PVKGKGYFVFHDAYGYFEKHYGLT 223
|
|
| TroA-like |
cd00636 |
Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function ... |
42-211 |
5.84e-07 |
|
Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between two globular domains linked by a single helix. Many of these proteins also possess a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence). The TroA-like proteins differ in their fold and ligand-binding mechanism from the PBPI and PBPII proteins, but are structurally similar, however, to the beta-subunit of the nitrogenase molybdenum-iron protein MoFe. Most TroA-like proteins are encoded by ABC-type operons and appear to function as periplasmic components of ABC transporters in metal ion uptake.
Pssm-ID: 238347 [Multi-domain] Cd Length: 148 Bit Score: 48.32 E-value: 5.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 42 KVVTSFSMIDDMVKEIGGEHVEVKNLVPTGTD-------------PHDYDPKPDDIKHIsSADLVFYNGLNLEggskGWL 108
Cdd:cd00636 2 RVVALDPGATELLLALGGDDKPVGVADPSGYPpeakallekvpdvGHGYEPNLEKIAAL-KPDLIIANGSGLE----AWL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080980409 109 fkalessDFSKENAIKTsegvkpkyikdedgkKEVNPHAFIDPKVGEKMIKNITKSLSernpknkdyYKENEKAYLKKLH 188
Cdd:cd00636 77 -------DKLSKIAIPV---------------VVVDEASELSLENIKESIRLIGKALG---------KEENAEELIAELD 125
|
170 180
....*....|....*....|...
gi 1080980409 189 NIEDDYEKQLGDIPKKDRVFVAS 211
Cdd:cd00636 126 ARLAELRAKLAKIPKKKVSLVVG 148
|
|
| NlpA |
COG1464 |
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion ... |
1-57 |
5.09e-03 |
|
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism];
Pssm-ID: 441073 [Multi-domain] Cd Length: 270 Bit Score: 37.78 E-value: 5.09e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1080980409 1 MKKVILFLFTITLSVVLAACSNGDKDGDSDkelesvDKDKIKVVTSFSMIDDMVKEI 57
Cdd:COG1464 1 MKKLLALLLALALALALAACGSSSAAAAAA------DKKTIKVGATPGPHAEILEVV 51
|
|
| |
