NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1081111669|gb|OFS61017|]
View 

DNA polymerase III subunit gamma/tau [Staphylococcus sp. HMSC034G11]

Protein Classification

DNA polymerase III subunit gamma/tau( domain architecture ID 11481115)

DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme; gamma and tau subunits are isoforms and either one or both may be present in the holoenzyme; gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-566 0e+00

DNA polymerase III subunits gamma and tau; Validated


:

Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 861.10  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK05563    1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK05563   81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK05563  161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESVHF-----------ESLIH 309
Cdd:PRK05563  241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEILdestendelfkELSEK 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 310 FDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAEMIKTQPqtvqnvatasvANEPDNEMLLQRLEQLENELKTLK 389
Cdd:PRK05563  321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQAAASP-----------EYDTELEVLLQRVEQLEQELKQLK 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 390 EQGIKTNKVSQQPKKPTRTIQRSKNTFSMQQIAKVLDKANKDDIKLLKNHWQEVIDHAKSNdKKSLVSLLLNSEPVAASE 469
Cdd:PRK05563  390 AQPVGVAPEQKEKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILESLKAQ-RKSLRALLVNSEPVAASE 468
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 470 DHVLVKFDEEIHCEIVNKDDEKRNNIESVVCNIVNKTVKVVGVPADQWLRVRAEYLQNRNTNETHQSEKQSTqqsqqiDI 549
Cdd:PRK05563  469 DTVVLAFEYEIHFEKAMLDKELNDTIENILSKLLGKSVEIVAVPEDEWQKIREEFLQKHKNEEEEEEEEEEL------PL 542
                         570
                  ....*....|....*..
gi 1081111669 550 AQKAKDLFGEETVHLVD 566
Cdd:PRK05563  543 IPEAKELFGEDLVEIID 559
 
Name Accession Description Interval E-value
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-566 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 861.10  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK05563    1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK05563   81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK05563  161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESVHF-----------ESLIH 309
Cdd:PRK05563  241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEILdestendelfkELSEK 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 310 FDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAEMIKTQPqtvqnvatasvANEPDNEMLLQRLEQLENELKTLK 389
Cdd:PRK05563  321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQAAASP-----------EYDTELEVLLQRVEQLEQELKQLK 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 390 EQGIKTNKVSQQPKKPTRTIQRSKNTFSMQQIAKVLDKANKDDIKLLKNHWQEVIDHAKSNdKKSLVSLLLNSEPVAASE 469
Cdd:PRK05563  390 AQPVGVAPEQKEKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILESLKAQ-RKSLRALLVNSEPVAASE 468
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 470 DHVLVKFDEEIHCEIVNKDDEKRNNIESVVCNIVNKTVKVVGVPADQWLRVRAEYLQNRNTNETHQSEKQSTqqsqqiDI 549
Cdd:PRK05563  469 DTVVLAFEYEIHFEKAMLDKELNDTIENILSKLLGKSVEIVAVPEDEWQKIREEFLQKHKNEEEEEEEEEEL------PL 542
                         570
                  ....*....|....*..
gi 1081111669 550 AQKAKDLFGEETVHLVD 566
Cdd:PRK05563  543 IPEAKELFGEDLVEIID 559
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-347 1.57e-180

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 512.50  E-value: 1.57e-180
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   3 YQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  83 TQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 163 PPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 243 SVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESV---------HFESL-IHFDL 312
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLlavleseqeFLKELaLKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1081111669 313 DMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLA 347
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-348 6.53e-163

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 467.36  E-value: 6.53e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQAlyrmyrPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:COG2812     1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDA-ASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEP 159
Cdd:COG2812    75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 160 HKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGderltLQDAln 239
Cdd:COG2812   155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFG-----LLDR-- 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 240 vtgsvdEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESVHFESLI----------H 309
Cdd:COG2812   228 ------RELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNEDererlqelarR 301
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1081111669 310 FDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAE 348
Cdd:COG2812   302 LSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 1.93e-55

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 184.34  E-value: 1.93e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  20 GQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGITQGTNNDVIEIDAASNN 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 100 -GVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAI 178
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 1081111669 179 S 179
Cdd:pfam13177 161 S 161
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 5.95e-24

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 94.88  E-value: 5.95e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1081111669 178 ISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTG 242
Cdd:cd18137     1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
41-176 1.28e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 51.22  E-value: 1.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   41 YIFSGPRGTGKTSIAKVFAKAINCLNSD----DGEPcnecaICKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYaps 116
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGviyiDGED-----ILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK--- 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1081111669  117 eSKYKVYIIDEVHMLTTGAFNALL--------KTLEEPPAHAIFILATTEPHKIPPTIISRaqRFDFK 176
Cdd:smart00382  77 -LKPDVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRR--RFDRR 141
 
Name Accession Description Interval E-value
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-566 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 861.10  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK05563    1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK05563   81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK05563  161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESVHF-----------ESLIH 309
Cdd:PRK05563  241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEILdestendelfkELSEK 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 310 FDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAEMIKTQPqtvqnvatasvANEPDNEMLLQRLEQLENELKTLK 389
Cdd:PRK05563  321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQAAASP-----------EYDTELEVLLQRVEQLEQELKQLK 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 390 EQGIKTNKVSQQPKKPTRTIQRSKNTFSMQQIAKVLDKANKDDIKLLKNHWQEVIDHAKSNdKKSLVSLLLNSEPVAASE 469
Cdd:PRK05563  390 AQPVGVAPEQKEKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILESLKAQ-RKSLRALLVNSEPVAASE 468
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 470 DHVLVKFDEEIHCEIVNKDDEKRNNIESVVCNIVNKTVKVVGVPADQWLRVRAEYLQNRNTNETHQSEKQSTqqsqqiDI 549
Cdd:PRK05563  469 DTVVLAFEYEIHFEKAMLDKELNDTIENILSKLLGKSVEIVAVPEDEWQKIREEFLQKHKNEEEEEEEEEEL------PL 542
                         570
                  ....*....|....*..
gi 1081111669 550 AQKAKDLFGEETVHLVD 566
Cdd:PRK05563  543 IPEAKELFGEDLVEIID 559
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-347 1.57e-180

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 512.50  E-value: 1.57e-180
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   3 YQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  83 TQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 163 PPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 243 SVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESV---------HFESL-IHFDL 312
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLlavleseqeFLKELaLKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1081111669 313 DMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLA 347
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-348 6.53e-163

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 467.36  E-value: 6.53e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQAlyrmyrPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:COG2812     1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDA-ASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEP 159
Cdd:COG2812    75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 160 HKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGderltLQDAln 239
Cdd:COG2812   155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFG-----LLDR-- 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 240 vtgsvdEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESVHFESLI----------H 309
Cdd:COG2812   228 ------RELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNEDererlqelarR 301
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1081111669 310 FDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAE 348
Cdd:COG2812   302 LSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1-534 2.55e-130

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 393.02  E-value: 2.55e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSD-DGEPCNECAIC 79
Cdd:PRK14950    1 MTVQVLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDpKGRPCGTCEMC 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  80 KGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEP 159
Cdd:PRK14950   81 RAIAEGSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 160 HKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTL---QD 236
Cdd:PRK14950  161 HKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLsqvQS 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 237 ALNVTGSVDEAALNElfnDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRD----------TIMNKTSNESVHFES 306
Cdd:PRK14950  241 LLGISGDEEVKALAE---ALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLRQvmllnsgadrSLLDLTADEKAALQK 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 307 LIH-FDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVK--LAEMIKTQPQTVQNVATASVANEPD-----NEMLLQRL 378
Cdd:PRK14950  318 VSQiANLEALTKWVKAFSQLDFQLRTTSYGQLPLELAVIEalLVPVPAPQPAKPTAAAPSPVRPTPApstrpKAAAAANI 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 379 EQLENELKTLKEQGIKTNKVSQQPKKPTRTIQRSKNTFSMQQIAKVLDK----------ANKDDIKL--LKNHWQEVIDH 446
Cdd:PRK14950  398 PPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAIPVDEKPKYTPpappkeeekaLIADGDVLeqLEAIWKQILRD 477
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 447 AKSNDKKslVSLLLNS--EPVAASEDHVLVKFDEEIHCEIVNKdDEKRNNIESVVCNIVNKTVKVVGVPADQWLRVRAEY 524
Cdd:PRK14950  478 VPPRSPA--VQALLSSgvRPVSVEKNTLTLSFKSKFHKDKIEE-PENRKITEELLSNFVGKTCAVRCTIEEKSEEPGDLR 554
                         570
                  ....*....|
gi 1081111669 525 LQNRNTNETH 534
Cdd:PRK14950  555 EQIREARKDH 564
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
1-562 4.89e-129

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 394.18  E-value: 4.89e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLN-SDDGEPCNECaic 79
Cdd:PRK07133    3 MKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSHkTDLLEPCQEC--- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  80 kgITQGTNN-DVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTE 158
Cdd:PRK07133   80 --IENVNNSlDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTE 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 159 PHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDAL 238
Cdd:PRK07133  158 VHKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVE 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 239 NVTGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIM-NKTSNESV----HFESL--IHFD 311
Cdd:PRK07133  238 ELFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKEFIIfNKTKDNSLleyySEEDLekLKID 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 312 LDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKL-------------AEMIKTQPQTVQNVATASVANEPDNEMLLQ-- 376
Cdd:PRK07133  318 DDFAYKFIEILFDLLKDLKISDNPNDTLEILIIKLlalseleeedeneIKFKKIEENSIDNLDIKEKKIENENDIEGKsd 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 377 ----RLEQLENELKTLKEQGIKTNK-VSQQPKKPTRTIQRSKNTFSmqqiakvLDKANKDDIKllknhwqEVIDHAKSND 451
Cdd:PRK07133  398 tknlEEGFETKDNKNKNSSFINKTEnILTNSPLKDELLEKTTEIIN-------IENPQEFEFG-------QIGNDIISTE 463
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 452 KKSLVSlllNSEPVAASEDHVLVKFDEEIHCEIVNKDDEKRNniESVVCNIVNKTVKVVGVPADQWLRVRAEYLQNRNTN 531
Cdd:PRK07133  464 IAQLDE---NQNLIDTGEFDLENNFSNSFNPENGNKIDENIN--ETFDTSTISANLSENKTNFAQSFNNKDTNLINSEIP 538
                         570       580       590
                  ....*....|....*....|....*....|.
gi 1081111669 532 ETHQSEKQSTQQSQQIDIAQKAKDLFGEETV 562
Cdd:PRK07133  539 IDLIKDTITINNSQKNVKKNGNKDYLSVEEV 569
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
1-264 1.81e-123

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 375.23  E-value: 1.81e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK14965    1 MSYLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14965   81 EITEGRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK14965  161 KVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAEL 240
                         250       260
                  ....*....|....*....|....
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAA 264
Cdd:PRK14965  241 LGVVDRRLLLDISAAVFGRDTRAL 264
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
1-453 1.08e-121

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 367.61  E-value: 1.08e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK14953    1 MMYIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14953   81 EIDKGSFPDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK14953  161 KIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEF 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESVHFESLIHF------DLDM 314
Cdd:PRK14953  241 LGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEIRNILLNKSLKNPEEVFQVEDFyrklekPLEA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 315 LYRMIDIINDTLVSIR-FSVNQSVHFEVLLVKLAEMIKTQPQTVQNVATASVANEPDNEmllqRLEQLENELKTLKEQGI 393
Cdd:PRK14953  321 LLYLEDVINKAFSEARtRDPLRAYELAILKLLYVKDIVPISELLKEGSKQETKEQPEKK----EEEKEELDIDKIILQII 396
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1081111669 394 KTNK--VSQQPKKPTRTIQRSKNTFsmqQIAKVLDKANKDDIKLLK----NHWQEVIDHAKSNDKK 453
Cdd:PRK14953  397 KNEGkiISAILKNAEIKEEEGKITI---KVEKSEEDTLDLEIKSIKkyfpFIEFEEVKKEKEKEKE 459
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
3-410 2.44e-115

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 349.84  E-value: 2.44e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   3 YQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLN-SDDGEPCNECAICKG 81
Cdd:PRK06305    4 YQVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNpTEDQEPCNQCASCKE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  82 ITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHK 161
Cdd:PRK06305   84 ISSGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHK 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 162 IPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVT 241
Cdd:PRK06305  164 IPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKAL 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 242 GSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSneSVHFESLIHFDLDMLYRMIDI 321
Cdd:PRK06305  244 GLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDLTLFFRNILLKQYN--KQLSSVATKYSSEQLLEIIDF 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 322 INDTLVSIRFSVNQSVHFEVLLVKLaemIKTqpqtvqnvatasvANEPDNEMLLQRLEQLENELKTLKEQGIKTNKVSQQ 401
Cdd:PRK06305  322 LGESAKHIQLTIFEKTFLETVIIHL---IRI-------------YQRPTLSQLVSQIKSPAFTQLRLESCPPQIKSSNSQ 385

                  ....*....
gi 1081111669 402 PKKPTRTIQ 410
Cdd:PRK06305  386 QTVSSPQPQ 394
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
1-544 4.93e-115

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 354.65  E-value: 4.93e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDD--GEPCNECAI 78
Cdd:PRK14948    1 MAYEPLHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNCLNSDKptPEPCGKCEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  79 CKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTE 158
Cdd:PRK14948   81 CRAIAAGNALDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 159 PHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQaIAFGDERLTLQDAL 238
Cdd:PRK14948  161 PQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQ-LSLLPGPITPEAVW 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 239 NVTGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNE-----SV---HFESLIHF 310
Cdd:PRK14948  240 DLLGAVPEQDLLNLLKALASNDPESLLDSCRQLLDRGREPLAILQGLAAFYRDLLLAKTAPNrpdlvAVsqqTWDELCKL 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 311 ----DLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAemiktqPQTVQNVATASVANEPDNEMLLQRLEQLENELK 386
Cdd:PRK14948  320 akqiNLERILQWQQHLKGSEYQLKNSTQPRLWLEVTLLGLL------PSAFISEIANASAPANPTPAPNPSPPPAPIQPS 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 387 TLKEQGIKTNKVSQQPKKPTRTIQRSKNTFSMQQIAKVLDKANkdDIKLLKNHWQEVidhaksndkksLVSLLLNSEPVA 466
Cdd:PRK14948  394 APKTKQAATTPSPPPAKASPPIPVPAEPTEPSPTPPANAANAP--PSLNLEELWQQI-----------LAKLELPSTRML 460
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 467 ASEDHVLVKFDEEihcEIV--------NKDDEKRNNIESVVCNIVNKTVKVVgvpadqwlrvraeyLQNRNTNETHQSEK 538
Cdd:PRK14948  461 LSQQAELVSLDSN---RAViavspnwlGMVQSRKPLLEQAFAKVLGRSIKLN--------------LESQSGSASNTAKT 523

                  ....*.
gi 1081111669 539 QSTQQS 544
Cdd:PRK14948  524 PPPPQK 529
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
4-392 1.54e-112

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 343.67  E-value: 1.54e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   4 QALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGIT 83
Cdd:PRK14962    2 EALYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSID 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  84 QGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIP 163
Cdd:PRK14962   82 EGTFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 164 PTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTGS 243
Cdd:PRK14962  162 PTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGL 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 244 VDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESVHFESlihfDLDMLYRMIDIIN 323
Cdd:PRK14962  242 IPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAIEDLVEDLERERANDIIQVSR----QLLNILREIKFAE 317
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1081111669 324 DTLVSIRF-SVNQSVHF---EVLLVKLAEMIKTQPQTVQNVATASVANEPDNEMLLQRLEQLENELKTLKEQG 392
Cdd:PRK14962  318 EKRLVCKLgSASIATRFsspNVQENDVEEKNDNSNVQQKEKKKEESKAKEEKQEDIEFEKRFKELMEELKEKG 390
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
8-424 7.36e-111

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 343.68  E-value: 7.36e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   8 RMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLN-SDDGEPCNECAICKGITQGT 86
Cdd:PRK14971    9 RKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNlTADGEACNECESCVAFNEQR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  87 NNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTI 166
Cdd:PRK14971   89 SYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTI 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 167 ISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQ---DALNV--- 240
Cdd:PRK14971  169 LSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKsviENLNIldy 248
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 -----------TGSVDEAALneLFNDIVKSdvkaAFNRyHHFisegkevnrlINDMIYFVRDTIMNKTS--------NES 301
Cdd:PRK14971  249 dyyfrltdallAGKVSDSLL--LFDEILNK----GFDG-SHF----------ITGLASHFRDLLVCKDAatlqllevGES 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 302 V---HFESLIHFDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAEMiktqPQTVQNVATASVANEPDNEMLLQRL 378
Cdd:PRK14971  312 IrqrYLEQAQKCPMSFLYRALKLCNQCDLNYRASKNKRLLVELTLIQLAQL----TQKGDDASGGRGPKQHIKPVFTQPA 387
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 1081111669 379 EQLENELKTLKEQGIKTNKVSQQPKKPT--RTIQRSKNTFSMQQIAKV 424
Cdd:PRK14971  388 AAPQPSAAAAASPSPSQSSAAAQPSAPQsaTQPAGTPPTVSVDPPAAV 435
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
1-451 8.18e-108

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 334.43  E-value: 8.18e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK06647    1 MSYRGTATKRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK06647   81 SIDNDNSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK06647  161 KLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNK--TSNESV------HF-ESLIHFD 311
Cdd:PRK06647  241 MGLTGDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLDCIEFFRELLFLKhgIKNEAFigikaeRLpEKLREFD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 312 LDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAEM--------IKTQPQTVQNVATASVANEPDNEMLLQRLEQLEN 383
Cdd:PRK06647  321 LSQIERAISVLLETYRDLQFSVNPRYELEINFSKILRLkdyvpnheLIKQIQDLESKLLEHAAPDSCNFDVGSDNESTDD 400
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1081111669 384 ELKTLKEQGIKT---NKVSQQPKKPTRTIQRSKNTFSMQQIAKVLDKANKDDIkllknhWQEVIDHA-KSND 451
Cdd:PRK06647  401 LSPIPIDPPLKAelpEIRSLEPDESTKEDEPLKTKIDSDMLSTESWDDEIDEI------FIEVRDNFdRSND 466
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-533 3.41e-107

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 334.12  E-value: 3.41e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK05896    1 MSEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK05896   81 SINTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK05896  161 KIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKT 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRD----------TIMNKTSNESVHFESLIHF 310
Cdd:PRK05896  241 FGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLIDllvyqktkniNLLKKLSKEQLKTLNLEKQ 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 311 DLDMLYRMIDIINDTLVS----IRFSVNQSVHFEVLLVKLAE-----------MIKTQPQTVQNVATASVANEPDNEM-- 373
Cdd:PRK05896  321 KLLSIEFNTNFLLNNFVSlinrLKASVNQVFEFEIYLYKIINanpdklenkkiEISIKPEKKTINNSQIITTKKINIVee 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 374 LLQRLEQLENELKTLKEQGIKTNKVSQQPKK-------PTRTIQRSKNTFSMQQIAKVLD----KANKDDIKLLKNHWQE 442
Cdd:PRK05896  401 SNKNSVHFDTLYKTKIFYHKKKINQNNKEQDikkeellEKEFVKKSEKIPKNDELLDNLElakqKFFNKDIELSKNMLQK 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 443 VIDHAKSNDKK-SLVSLLLNSEPVAASEDHVLVKF-DEEIHCEIVNKDDEKRNNIESVVcNIVNKTVKVVGVPADQWLRV 520
Cdd:PRK05896  481 FNKFKNEESAEnSFIDIIKQADLVLWVSPNALILGvEDLGLIELINKVNESFEFIKTIF-KKFNKNKLVIAISKKQATKI 559
                         570
                  ....*....|....*.
gi 1081111669 521 ---RAEYLQNRNTNET 533
Cdd:PRK05896  560 tniKNQKLKTNIINDV 575
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-245 4.80e-105

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 329.52  E-value: 4.80e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINClnsDDG---EPCNECA 77
Cdd:PRK07994    1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNC---ETGitaTPCGECD 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  78 ICKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATT 157
Cdd:PRK07994   78 NCREIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATT 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 158 EPHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDA 237
Cdd:PRK07994  158 DPQKLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDV 237

                  ....*...
gi 1081111669 238 LNVTGSVD 245
Cdd:PRK07994  238 SAMLGTLD 245
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
3-265 8.63e-102

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 319.54  E-value: 8.63e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   3 YQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSD-DGEP----CNECA 77
Cdd:PRK09111   11 YRVLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGPDgDGGPtidlCGVGE 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  78 ICKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATT 157
Cdd:PRK09111   91 HCQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATT 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 158 EPHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDA 237
Cdd:PRK09111  171 EIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTAEAV 250
                         250       260
                  ....*....|....*....|....*...
gi 1081111669 238 LNVTGSVDEAALNELFNDIVKSDVKAAF 265
Cdd:PRK09111  251 RDMLGLADRARVIDLFEALMRGDVAAAL 278
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
1-263 1.24e-101

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 322.81  E-value: 1.24e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK08691    1 MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK08691   81 QIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK08691  161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM 240
                         250       260
                  ....*....|....*....|...
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKA 263
Cdd:PRK08691  241 IGAVDKQYLYELLTGIINQDGAA 263
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
1-266 3.50e-100

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 313.22  E-value: 3.50e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK14969    1 MSYQVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14969   81 EIDSGRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK14969  161 KIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAM 240
                         250       260
                  ....*....|....*....|....*.
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFN 266
Cdd:PRK14969  241 LGAIDQDYLFALLEALLAQDGAALLA 266
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1-413 1.27e-99

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 314.96  E-value: 1.27e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDG--------EP 72
Cdd:PRK14954    1 MSYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDpvylqevtEP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  73 CNECAICKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIF 152
Cdd:PRK14954   81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 153 ILATTEPHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAF----- 227
Cdd:PRK14954  161 IFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFsvgse 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 228 GDERLTLQDALNVTGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIM--NKTSN------ 299
Cdd:PRK14954  241 AEKVIAYQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDEQDFLEKLIEHFRNFLVlyNLRSTrlierp 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 300 ESV---HFESLIHFDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAEMIKTQPQTvqnvaTASVANEPDnemllq 376
Cdd:PRK14954  321 ESVkerYQQSAGGLTPAAVMQMTDFLMKTQGELKFQFEYQFRFELALLRLIELVRNDGGV-----APSPAGSPD------ 389
                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 1081111669 377 rleqlenELKTLKEQGIKTNKVSQQPKKPTRTIQRSK 413
Cdd:PRK14954  390 -------VKKKAPEPDLPQPDRHPGPAKPEAPGARPA 419
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
4-427 6.50e-96

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 302.72  E-value: 6.50e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   4 QALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGIT 83
Cdd:PRK08451    2 QALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSAL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  84 QGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIP 163
Cdd:PRK08451   82 ENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 164 PTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTGS 243
Cdd:PRK08451  162 ATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGL 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 244 VDEAALNELFNDIVKSDVKAAFNRYHhfISEGKEVNRLINDMIYFVRDTIMNKTSNesvhfeslihFDLDMLYRMIDIIN 323
Cdd:PRK08451  242 LDPSKLEDFFQAILNQDKEKLFELLK--ELEDYEAEMVLDEMMLFLKEKFLSKDSE----------FSILLYERFFRILS 309
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 324 DTLVSIRFSVNQSVHFEVLLVKLAEMIKtqpqtvqnvatasvanepdnemlLQRLEQLENELKTLKEQGIK----TNKVS 399
Cdd:PRK08451  310 SAKSLLKEGADDGFVLLLMLFKMKEALK-----------------------LKEIDDAIEELEQEKTTAIIplntPAPII 366
                         410       420
                  ....*....|....*....|....*...
gi 1081111669 400 QQPKKPTRTIQRSKNTFSMQQiAKVLDK 427
Cdd:PRK08451  367 PNTEKEEAKDRIFKNLFEQLL-DKIYDR 393
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
1-354 1.09e-95

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 297.57  E-value: 1.09e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLN-SDDG-------EP 72
Cdd:PRK14955    1 MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRmIDDAdylqevtEP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  73 CNECAICKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIF 152
Cdd:PRK14955   81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 153 ILATTEPHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAF----- 227
Cdd:PRK14955  161 IFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAFsvese 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 228 GDERLTLQDALNVTGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIM--NKTSNESVHFE 305
Cdd:PRK14955  241 GEGSIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVvhNLRSTRLVERP 320
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1081111669 306 SLI---------HFDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAEMIKTQP 354
Cdd:PRK14955  321 DAVreryerdaaKFSPEVIMQMTDLLLQTQKELKFQFEYQFRFELALLKLIEIGHPAP 378
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
3-438 1.96e-95

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 299.94  E-value: 1.96e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   3 YQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGI 82
Cdd:PRK14956    5 HEVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEI 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  83 TQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:PRK14956   85 TKGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKI 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 163 PPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTG 242
Cdd:PRK14956  165 PETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMIG 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 243 SVDEAALNELFNDIVKSDVKA-AFNRYHHFISEGKEVNRLINDMIYF------VRDTIMNKtsnESVHF----------- 304
Cdd:PRK14956  245 YHGIEFLTSFIKSLIDPDNHSkSLEILESLYQEGQDIYKFLWDSIEFthtlnlIRDSLADR---ESVNFpkedlqkmksd 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 305 -----ESLIHFDLDMLYRMIDIINdtLVSIRFSVNQSVHFEVLLVKLAEMIkTQPqtvqnvataSVANepdnemLLQRLE 379
Cdd:PRK14956  322 fenvdSSKLNFLSGKLFEIYEKIK--TIRLRNSFEIKVFTEIQIKKLVEEL-TYP---------SLAG------LLDKIN 383
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1081111669 380 QLENELKTLKEQGIKTNKVSQQPKKPTRTIQRSK---NTFSMQQIAKVLDkANKDDIKLLKN 438
Cdd:PRK14956  384 HLILMVQGSKNIPEDVEPVKKISTPPPLQQEASKkkdPTTSDQKLNSQFE-SNQQDSNLDNN 444
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
4-474 1.43e-94

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 300.64  E-value: 1.43e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   4 QALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGIT 83
Cdd:PRK14952    1 MALYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVALA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  84 QGTNN--DVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHK 161
Cdd:PRK14952   81 PNGPGsiDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 162 IPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIA-FGDERLTLQDALNV 240
Cdd:PRK14952  161 VLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAgAADTHVTYQRALGL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESVHfESLIHFDLDMLYRMID 320
Cdd:PRK14952  241 LGATDVALIDDAVDALAADDAAALFGAIESVIDAGHDPRRFATDLLERFRDLIVLQAVPDAAA-RGVVDAPEDVLERMRE 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 321 IindtlvSIRFSVNQSVHF-EVLLVKLAEMI-KTQPQTVQNVATAS--VANEPDNE-MLLQRLEQLENELktlkEQGIKT 395
Cdd:PRK14952  320 Q------AARIGLATLTRYaEVVQAGLGEMRgATAPRLLLEVVCARllLPSASDAEsALLQRVERIETRL----DMSIPA 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 396 NKVSQQPK-----KPTRTIQRSKNTFSMQQIAKVLDKANKDDIKLLKNHWQEVIDHAKSNDKKSLVslLLNSEPVAASED 470
Cdd:PRK14952  390 NLLHNAPQaapapSAAAPEPKHQPAPEPRPVLAPTPASGEPNAAAVRSMWSTVRDKVRQRSRTTEV--MLAGATVRALEG 467

                  ....
gi 1081111669 471 HVLV 474
Cdd:PRK14952  468 NTLV 471
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
5-265 2.26e-91

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 289.82  E-value: 2.26e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   5 ALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDgEPCNECAICKGITQ 84
Cdd:PRK14963    3 ALYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNCSGEDP-KPCGECESCLAVRR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  85 GTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPP 164
Cdd:PRK14963   82 GAHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 165 TIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDErLTLQDALNVTGSV 244
Cdd:PRK14963  162 TILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLALGTP-VTRKQVEEALGLP 240
                         250       260
                  ....*....|....*....|.
gi 1081111669 245 DEAALNELFNDIVKSDVKAAF 265
Cdd:PRK14963  241 PQERLRGIAAALAQGDAAEAL 261
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
1-261 8.49e-91

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 299.33  E-value: 8.49e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK14949    1 MSYQVLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14949   81 EIAQGRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK14949  161 KLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLTQVQTM 240
                         250       260
                  ....*....|....*....|.
gi 1081111669 241 TGSVDEAALNELFNDIVKSDV 261
Cdd:PRK14949  241 LGSIDEQHVIALLKALTDADI 261
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
1-301 5.70e-90

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 289.66  E-value: 5.70e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK14959    1 MSHASLTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14959   81 KVTQGMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK14959  161 KFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGV 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNES 301
Cdd:PRK14959  241 LGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVATWRNLFMLRQAGEA 301
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1-260 7.95e-90

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 291.39  E-value: 7.95e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDD-----GEPCNE 75
Cdd:PRK12323    1 MSYQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGADGeggitAQPCGQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  76 CAICKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILA 155
Cdd:PRK12323   81 CRACTEIDAGRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 156 TTEPHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQ 235
Cdd:PRK12323  161 TTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEE 240
                         250       260
                  ....*....|....*....|....*
gi 1081111669 236 DALNVTGSVDEAALNELFNDIVKSD 260
Cdd:PRK12323  241 AVRGMLGAIDQSYLVRLLDALAAED 265
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
1-245 5.84e-89

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 287.00  E-value: 5.84e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSD-----DGEPCNE 75
Cdd:PRK14951    1 MSYLVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQGPDgqggiTATPCGV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  76 CAICKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILA 155
Cdd:PRK14951   81 CQACRDIDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 156 TTEPHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQ 235
Cdd:PRK14951  161 TTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEA 240
                         250
                  ....*....|
gi 1081111669 236 DALNVTGSVD 245
Cdd:PRK14951  241 AVRQMLGSVD 250
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
10-512 5.99e-89

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 283.21  E-value: 5.99e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  10 YRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGITQGTNND 89
Cdd:PRK14964    7 YRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNSNHPD 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  90 VIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISR 169
Cdd:PRK14964   87 VIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVTIISR 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 170 AQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTGSVDEAAL 249
Cdd:PRK14964  167 CQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCVDKHIL 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 250 NELFNDIVKSDVKAAFNRYHHFISEGKEVNRLIN--DMIYFVRDTIMNKTsnesvhfeslIHFDLDmlyrmidiiNDTLV 327
Cdd:PRK14964  247 EDLVEAILLGDAQSALNVFRELCNTSNPVIILEGmlQIIYEICYFSITKE----------IDFLLG---------EDLIT 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 328 SIRFSVNQSVHFevlLVKLAEMIKTQPQTVQNVATASVAnepdNEMLLQRL-------------EQLENELKTLKEQGIK 394
Cdd:PRK14964  308 RIKSLKIGSTIF---LSRLWQMLLKGIQEVKSSTCVKQA----AEMMIIRLcylsdlpspqqiiKKILSKSVEQAPRQIK 380
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 395 TNKVSQQ--PKKPTRTIQRSKNTFSMQQIAKVLDKANKDDIKLLKNHWQEVIDHAKSNDKKSLVSLLLNSEPVAASedhv 472
Cdd:PRK14964  381 VNNKQQNydFDKLLQLLKSNNMIDLYNQLCSSLQEIDCKSDYTLNIKANSQLDSNFCNDLKNFLNQLTNKKWNICI---- 456
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|..
gi 1081111669 473 lvkfdEEIHCEIVNKDDekrnniESVVCNIVN--KTVKVVGV 512
Cdd:PRK14964  457 -----DKNSNLVYNPEL------DEAVKDILQefDGAKVVNI 487
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
8-364 1.36e-88

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 277.91  E-value: 1.36e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   8 RMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEpcnecaickgitQGTN 87
Cdd:PRK14970    9 RKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDDPN------------EDFS 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  88 NDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTII 167
Cdd:PRK14970   77 FNIFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTIL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 168 SRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTGSVDEA 247
Cdd:PRK14970  157 SRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNILDYD 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 248 ALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKT-----------SNESVHFESLIHFDLDMLY 316
Cdd:PRK14970  237 TYINVTDLILENKIPELLLAFNEILRKGFDGHHFIAGLASHFRDLMVSKTpatiallevgeQAKKRYEVQSQKVSQSFLL 316
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1081111669 317 RMIDIINDTLVSIRFSVNQSVHFEVLLVKLAEMI---KTQPQTVQNVATAS 364
Cdd:PRK14970  317 SGIDIANDCDLKYKLSKNQRLLVELALMQLASINfdgISAKKKLSDLKKKV 367
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
5-382 5.76e-88

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 289.19  E-value: 5.76e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   5 ALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGI-T 83
Cdd:PRK07764    4 ALYRRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVALaP 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  84 QGTNN-DVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:PRK07764   84 GGPGSlDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKV 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 163 PPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIA-FGDERLTLQDALNVT 241
Cdd:PRK07764  164 IGTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQLLAgAGPEGVTYERAVALL 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 242 GSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRD-TIMNKTSNEsvhFES-LI----------- 308
Cdd:PRK07764  244 GVTDSALIDEAVDALAAGDGAALFGTVDRVIEAGHDPRRFAEDLLERLRDlIVLQAVPDA---AERgLVdapadqldrmr 320
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1081111669 309 ----HFDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVKLAemiktqpqtvqnVATASvanePDNEMLLQRLEQLE 382
Cdd:PRK07764  321 aqaqRLGPAELTRAADVVNDGLTEMRGATSPRLLLELLCARML------------LPSAS----DDERGLLARLERLE 382
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
1-296 3.01e-87

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 274.38  E-value: 3.01e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK14961    1 MNYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14961   81 EIEKGLCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK14961  161 KIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDM 240
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNK 296
Cdd:PRK14961  241 LGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWENILIEMLRFLHHISMSQ 296
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1-260 2.96e-82

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 274.03  E-value: 2.96e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK07003    1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK07003   81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK07003  161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM 240
                         250       260
                  ....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSD 260
Cdd:PRK07003  241 LGALDQTYMVRLLDALAAGD 260
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
3-252 1.01e-81

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 269.99  E-value: 1.01e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   3 YQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGI 82
Cdd:PRK14960    2 YQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  83 TQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:PRK14960   82 NEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKL 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 163 PPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTG 242
Cdd:PRK14960  162 PITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLG 241
                         250
                  ....*....|
gi 1081111669 243 SVDEAALNEL 252
Cdd:PRK14960  242 LIDRTIIYDL 251
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
1-420 2.31e-78

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 256.93  E-value: 2.31e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK14957    1 MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14957   81 AINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK14957  161 KIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDM--IYFVRDTIMNKTSNESVHfeslihfDLDmlyrm 318
Cdd:PRK14957  241 LGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIaeIWFACCIYSFTQSLDAVN-------DID----- 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 319 IDIINDTLVSIrfSVNQSvHFevlLVKLAEMIKTQPQTVQNVATASVanepdneMLLQRLEQLENELKTLKEQGIKTNKV 398
Cdd:PRK14957  309 VDIINNILAKI--SIEQA-HF---LYQLTITAKKDIALAPNFETGVT-------MAILRLIAFQKKNLIDKTQTSKSNIS 375
                         410       420
                  ....*....|....*....|..
gi 1081111669 399 SQQPKKptrTIQRSKNTFSMQQ 420
Cdd:PRK14957  376 PIVSKN---DINLLKNTFKSEQ 394
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
3-345 4.14e-72

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 239.38  E-value: 4.14e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   3 YQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCL----NSDDGEPCNECAI 78
Cdd:PRK06645    8 YIPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSalitENTTIKTCEQCTN 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  79 CKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTE 158
Cdd:PRK06645   88 CISFNNHNHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTE 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 159 PHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFG---DERLTLQ 235
Cdd:PRK06645  168 VQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSaksDNIISPQ 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 236 DALNVTGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLIN---DMIYFVRDTIMNKTSNESVhFES------ 306
Cdd:PRK06645  248 VINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIEsvsDFIAYLNKVKMLPNYSLPI-YESfndrtk 326
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1081111669 307 --LIHFDLDMLYRMIDIINDTLVSIRFSVNQSVHFEVLLVK 345
Cdd:PRK06645  327 siLDKISLPHLSILWQIYNKGVGEIKISYNQLTETEMLVIK 367
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
1-333 5.58e-70

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 233.85  E-value: 5.58e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   1 MDYQALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICK 80
Cdd:PRK14958    1 MAHQVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  81 GITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH 160
Cdd:PRK14958   81 EIDEGRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNV 240
Cdd:PRK14958  161 KLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 241 TGSVDEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNesvhfESLIHFDLDMLYRMID 320
Cdd:PRK14958  241 LGTIEPLLLFDILEALAAKAGDRLLGCVTRLVEQGVDFSNALADLLSLLHQIAIIQTVP-----EALIENDSEQLRQLAK 315
                         330
                  ....*....|...
gi 1081111669 321 IINDTLVSIRFSV 333
Cdd:PRK14958  316 LLDREDVQLFYQI 328
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
21-349 2.27e-64

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 212.14  E-value: 2.27e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  21 QTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAiCKGITQGTNNDVIEIDAASNN- 99
Cdd:COG0470     1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELNPEEKSd 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 100 --GVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKA 177
Cdd:COG0470    80 qiGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 178 ISSDQIIDRLkyvansQSLDYDDAALEFIAKASEGGMRDALSIMdQAIAfgdERLTLQDALNVTGSVDEAAlnELFNDIV 257
Cdd:COG0470   160 PSEEEALAWL------REEGVDEDALEAILRLAGGDPRAAINLL-QALA---GRKELLEDLAALLSRDRAL--ELLDALL 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 258 KSDVKAAFNryhhfisegkEVNRLINDMIYfvrdtimnktsnesvhfeslIHFDLDMLYRMIDIINDTLVSIRFSVNQSV 337
Cdd:COG0470   228 KAEALELLD----------WLLKWLLDNLP--------------------LEYAGEDLARAYEALSEADRRLGRYANDRL 277
                         330
                  ....*....|..
gi 1081111669 338 HFEVLLVKLAEM 349
Cdd:COG0470   278 LLEALLAKLGRL 289
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
26-212 6.60e-56

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 186.29  E-value: 6.60e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  26 KTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGITQGTNNDVIEIDAASNN-GVDEI 104
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSiKVDQV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 105 RNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISSDQII 184
Cdd:TIGR00678  82 RELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALL 161
                         170       180
                  ....*....|....*....|....*...
gi 1081111669 185 DRLKYVANSQsldyddAALEFIAKASEG 212
Cdd:TIGR00678 162 QWLIRQGISE------EAAELLLALAGG 183
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 1.93e-55

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 184.34  E-value: 1.93e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  20 GQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGITQGTNNDVIEIDAASNN 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 100 -GVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAI 178
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 1081111669 179 S 179
Cdd:pfam13177 161 S 161
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
21-187 9.01e-44

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 158.55  E-value: 9.01e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  21 QTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGITQGTNNDVIEI--DAASN 98
Cdd:PRK08058   11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVapDGQSI 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  99 NgVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAI 178
Cdd:PRK08058   91 K-KDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPL 169

                  ....*....
gi 1081111669 179 SSDQIIDRL 187
Cdd:PRK08058  170 PPESLIQRL 178
rfc PRK00440
replication factor C small subunit; Reviewed
10-264 1.56e-33

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 129.99  E-value: 1.56e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  10 YRPQSFDDVVGQTHVTKTLRNAISKGKQSHaYIFSGPRGTGKTSIAKVFAKAINclnsddGEPCNEcaickgitqgtnnD 89
Cdd:PRK00440   11 YRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALARELY------GEDWRE-------------N 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  90 VIEIDAASNNGVDEIRN-IRDKVKYAPS-ESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTII 167
Cdd:PRK00440   71 FLELNASDERGIDVIRNkIKEFARTAPVgGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQ 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 168 SRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMdQAIAFGDERLTLQDALNVTGSVDEA 247
Cdd:PRK00440  151 SRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINAL-QAAAATGKEVTEEAVYKITGTARPE 229
                         250
                  ....*....|....*..
gi 1081111669 248 ALNELFNDIVKSDVKAA 264
Cdd:PRK00440  230 EIREMIELALNGDFTEA 246
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
10-264 8.22e-33

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 128.57  E-value: 8.22e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  10 YRPQSFDDVVGQTHVTKTLRNAISKGKQSHaYIFSGPRGTGKTSIAKVFAKAINclnsddGEPcnecaickgitqgTNND 89
Cdd:PRK12402    9 YRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALARELY------GDP-------------WENN 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  90 VIEIDAAS--NNGVDEIRN-----------------IRDKVK--------YAPSESKYKVYIIDEVHMLTTGAFNALLKT 142
Cdd:PRK12402   69 FTEFNVADffDQGKKYLVEdprfahflgtdkrirssKIDNFKhvlkeyasYRPLSADYKTILLDNAEALREDAQQALRRI 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 143 LEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALsIMD 222
Cdd:PRK12402  149 MEQYSRTCRFIIATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAI-LTL 227
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1081111669 223 QAIAFGDERLTLQDALNVTGSVD-EAALNELFNDIVKSDVKAA 264
Cdd:PRK12402  228 QTAALAAGEITMEAAYEALGDVGtDEVIESLLDAAEAGDFTDA 270
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
7-243 4.12e-32

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 128.28  E-value: 4.12e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   7 YRMyRPQSFDDVVGQTHVT---KTLRNAISKGKQSHAyIFSGPRGTGKTSIAKVFAKAinclnsddgepcnecaickgit 83
Cdd:PRK13342    4 ERM-RPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGA---------------------- 59
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  84 qgTNNDVIEIDAAsNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHmlttgAFN-----ALLKTLEEppAHAIFILATTE 158
Cdd:PRK13342   60 --TDAPFEALSAV-TSGVKDLREVIEEARQRRSAGRRTILFIDEIH-----RFNkaqqdALLPHVED--GTITLIGATTE 129
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 159 -P-HKIPPTIISRAQRFDFKAISSD---QIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGdERLT 233
Cdd:PRK13342  130 nPsFEVNPALLSRAQVFELKPLSEEdieQLLKRALEDKERGLVELDDEALDALARLANGDARRALNLLELAALGV-DSIT 208
                         250
                  ....*....|
gi 1081111669 234 LQDALNVTGS 243
Cdd:PRK13342  209 LELLEEALQK 218
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
15-212 5.25e-32

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 127.34  E-value: 5.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  15 FDDVVGQTHVTKTLRNA---------ISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINClnSDDGEP-CNECAICKGITQ 84
Cdd:PRK07940    4 WDDLVGQEAVVAELRAAaraaradvaAAGSGMTHAWLFTGPPGSGRSVAARAFAAALQC--TDPDEPgCGECRACRTVLA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  85 GTNNDV--IEIDAASNnGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKI 162
Cdd:PRK07940   82 GTHPDVrvVAPEGLSI-GVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDV 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1081111669 163 PPTIISRAQRFDFKAISSDQIIDRLkyvANSQSLDYDDAalEFIAKASEG 212
Cdd:PRK07940  161 LPTIRSRCRHVALRTPSVEAVAEVL---VRRDGVDPETA--RRAARASQG 205
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
15-212 9.32e-32

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 125.01  E-value: 9.32e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  15 FDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAIncLNSDDGEPCNECAICKG------------I 82
Cdd:PRK07399    3 FANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGL--LSQGSPSKNIRRRLEEGnhpdllwveptyQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  83 TQGT--NNDVIEIDAASNNG-----VDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEpPAHAIFILA 155
Cdd:PRK07399   81 HQGKliTASEAEEAGLKRKAppqirLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEE-PGNGTLILI 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1081111669 156 TTEPHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEG 212
Cdd:PRK07399  160 APSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPELLALAQGSPG 216
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
14-348 1.61e-26

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 110.12  E-value: 1.61e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  14 SFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAInclnsddgepcnecaicKGITQGTNN-DVIE 92
Cdd:PRK05564    2 SFHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIALKI-----------------LGKSQQREYvDIIE 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  93 IDAASNN--GVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRA 170
Cdd:PRK05564   65 FKPINKKsiGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRC 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 171 QRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFiakaSEGgmrdalsIMDQAIAF-GDErlTLQDALNVTgsvdeaal 249
Cdd:PRK05564  145 QIYKLNRLSKEEIEKFISYKYNDIKEEEKKSAIAF----SDG-------IPGKVEKFiEDD--SLKNIRNMS-------- 203
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 250 NELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIMNKTSNESvhfESLIHFD-------------LDMLY 316
Cdd:PRK05564  204 LEILKDIKKSNINILLKYENFLIKYKENWEEILTCILSYIRDSLLYKETGNE---ELIINIDkiedikhisekfsYKKLN 280
                         330       340       350
                  ....*....|....*....|....*....|..
gi 1081111669 317 RMIDIINDTLVSIRFSVNQSVHFEVLLVKLAE 348
Cdd:PRK05564  281 KMIEIINDTRDNLSSNVNPTLVFDSMLIKMQE 312
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
7-242 2.01e-26

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 112.07  E-value: 2.01e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   7 YRMyRPQSFDDVVGQTHVT---KTLRNAISKGkQSHAYIFSGPRGTGKTSIAKVFAKAinclnsddgepcnecaickgit 83
Cdd:COG2256    17 ERM-RPRTLDEVVGQEHLLgpgKPLRRAIEAG-RLSSMILWGPPGTGKTTLARLIANA---------------------- 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  84 qgTNNDVIEIDAASnNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHmlttgAFN-----ALLKTLEEppAHAIFILATTE 158
Cdd:COG2256    73 --TDAEFVALSAVT-SGVKDIREVIEEARERRAYGRRTILFVDEIH-----RFNkaqqdALLPHVED--GTITLIGATTE 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 159 -P-HKIPPTIISRAQRFDFKAISSD---QIIDR----LKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAF-- 227
Cdd:COG2256   143 nPsFEVNSALLSRCRVFVLKPLSEEdleQLLERaladDERGLGGYKLELDDEALEALARLADGDARRALNALELAVLSap 222
                         250
                  ....*....|....*..
gi 1081111669 228 --GDERLTLQDALNVTG 242
Cdd:COG2256   223 pdGVIEITLELVEEALQ 239
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
34-223 6.38e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 105.56  E-value: 6.38e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  34 KGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGITQGTNND--VIEIDAASNN-GVDEIRNIRDK 110
Cdd:PRK05707   18 RGRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDnfVLEPEEADKTiKVDQVRELVSF 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 111 VKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISSDQIIDRLKyv 190
Cdd:PRK05707   98 VVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESLQWLQ-- 175
                         170       180       190
                  ....*....|....*....|....*....|...
gi 1081111669 191 anSQSLDYDDAALEFIAKASEGGMRDALSIMDQ 223
Cdd:PRK05707  176 --QALPESDERERIELLTLAGGSPLRALQLHEQ 206
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 5.95e-24

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 94.88  E-value: 5.95e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1081111669 178 ISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGDERLTLQDALNVTG 242
Cdd:cd18137     1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
40-234 1.02e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 102.26  E-value: 1.02e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  40 AYIFSGPRGTGKTSIAKVFAKAINCLNSDDG-EPCNECAICKGITQGTNNDVIEIDAASN---NG-------VDEIRNIR 108
Cdd:PRK08699   23 AWLFAGKKGIGKTAFARFAAQALLCETPAPGhKPCGECMSCHLFGQGSHPDFYEITPLSDepeNGrkllqikIDAVREII 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 109 DKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISSDQIIDRLK 188
Cdd:PRK08699  103 DNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAPSHEEALAYLR 182
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1081111669 189 Y--VANSQS----------LDYDDAALEFIAKASEG-GMRDALSIMDQAIAFGDERLTL 234
Cdd:PRK08699  183 ErgVAEPEErlafhsgaplFDEEPELRALRIKLLDIlAEPRLLKILDYAALFDKEKLPL 241
PLN03025 PLN03025
replication factor C subunit; Provisional
10-294 2.50e-23

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 100.96  E-value: 2.50e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  10 YRPQSFDDVVGQTHVTKTLRnAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGepcnecaickgitqgtnnd 89
Cdd:PLN03025    7 YRPTKLDDIVGNEDAVSRLQ-VIARDGNMPNLILSGPPGTGKTTSILALAHELLGPNYKEA------------------- 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  90 VIEIDAASNNGVDEIRN-----IRDKVKYAPSesKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPP 164
Cdd:PLN03025   67 VLELNASDDRGIDVVRNkikmfAQKKVTLPPG--RHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIE 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 165 TIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMdQAIAFGDERLTLQDALNVTGSV 244
Cdd:PLN03025  145 PIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNL-QATHSGFGFVNQENVFKVCDQP 223
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1081111669 245 DEAALNELFNDIVKSDVKAAFNRYHHFISEGKEVNRLINDMIYFVRDTIM 294
Cdd:PLN03025  224 HPLHVKNIVRNCLKGKFDDACDGLKQLYDLGYSPTDIITTLFRVVKNYDM 273
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
12-218 2.54e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 98.57  E-value: 2.54e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  12 PQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAkvFAKAINCLNSDD--------GEPCNECAICKGIT 83
Cdd:PRK09112   19 PSENTRLFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLA--FHLANHILSHPDpaeapetlADPDPASPVWRQIA 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  84 QGTNNDVIEID---------AASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFIL 154
Cdd:PRK09112   97 QGAHPNLLHITrpfdektgkFKTAITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFIL 176
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1081111669 155 ATTEPHKIPPTIISRAQRFDFKAISSDQIIDRLKYVANSQSLdyDDAALEFIAKASEGGMRDAL 218
Cdd:PRK09112  177 ISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHLGSSQGS--DGEITEALLQRSKGSVRKAL 238
PRK04195 PRK04195
replication factor C large subunit; Provisional
10-260 7.51e-21

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 95.76  E-value: 7.51e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  10 YRPQSFDDVVGQTHVTKTLR---NAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINClnsddgepcnecaickgitqgt 86
Cdd:PRK04195    8 YRPKTLSDVVGNEKAKEQLRewiESWLKGKPKKALLLYGPPGVGKTSLAHALANDYGW---------------------- 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  87 nnDVIEIDAASNNGVDEIRNIrdkVKYAPSES-----KYKVYIIDEVHMLT----TGAFNALLKTLEEPpAHAIfILATT 157
Cdd:PRK04195   66 --EVIELNASDQRTADVIERV---AGEAATSGslfgaRRKLILLDEVDGIHgnedRGGARAILELIKKA-KQPI-ILTAN 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 158 EPHKIPP-TIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDAlsIMD-QAIAFGDERLTLQ 235
Cdd:PRK04195  139 DPYDPSLrELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSA--INDlQAIAEGYGKLTLE 216
                         250       260
                  ....*....|....*....|....*
gi 1081111669 236 DALNVTGSVDEAALNELFNDIVKSD 260
Cdd:PRK04195  217 DVKTLGRRDREESIFDALDAVFKAR 241
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
31-188 9.08e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 93.65  E-value: 9.08e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  31 AISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGITQGTNNDVIEIDAASNN--GVDEIRNIR 108
Cdd:PRK06871   17 AFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPIDNKdiGVDQVREIN 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 109 DKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISSDQIIDRLK 188
Cdd:PRK06871   97 EKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTWLIHPPEEQQALDWLQ 176
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
39-213 1.36e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 93.29  E-value: 1.36e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  39 HAYIFSGPRGTGKTSIAKVFAKAINCLN-SDDGEPCNECAICKGITQGTNND-------VIEIDAASNNG---------- 100
Cdd:PRK06964   22 HALLLHGQAGIGKLDFAQHLAQGLLCETpQPDGEPCGTCAACNWFAQGNHPDyrivrpeALAAEAPGAADeakeadadeg 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 101 ------------VDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIIS 168
Cdd:PRK06964  102 gkktkapskeikIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLPTILS 181
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1081111669 169 RAQRFDFKAISSDQIIDRLKyvanSQSLDYDDAALefiakASEGG 213
Cdd:PRK06964  182 RCRQFPMTVPAPEAAAAWLA----AQGVADADALL-----AEAGG 217
44 PHA02544
clamp loader, small subunit; Provisional
5-347 1.10e-19

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 90.05  E-value: 1.10e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   5 ALYRMYRPQSFDDVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFakainclnsddgepCNEcaickgitq 84
Cdd:PHA02544   10 MWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTVAKAL--------------CNE--------- 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  85 gTNNDVIEIDAASNNgVDEIRNirDKVKYAPSES---KYKVYIIDEVHMLTTGAFNALLKTL-EEPPAHAIFILATTEPH 160
Cdd:PHA02544   67 -VGAEVLFVNGSDCR-IDFVRN--RLTRFASTVSltgGGKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITANNKN 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 161 KIPPTIISRAQRFDFKAISSD-------QIIDRLKYVANSQSLDYDDAAL-EFIAKaseggmrdalsimdqaiAFGDERL 232
Cdd:PHA02544  143 GIIEPLRSRCRVIDFGVPTKEeqiemmkQMIVRCKGILEAEGVEVDMKVLaALVKK-----------------NFPDFRR 205
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 233 TLQ--DALNVTGSVDEAALNELFNDIVKSDVKAAFNRyhhfisEGKEVNRLINDMIYFVrDTIMNKTSNE---SVHFESL 307
Cdd:PHA02544  206 TINelQRYASTGKIDAGILSEVTNSDIDDVVEALKAK------DFKAVRALAPNYANDY-ASFVGKLYDElypQVTPPSI 278
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1081111669 308 IhfdldmlyRMIDIINDTLVSIRFSVNQSVHFEVLLVKLA 347
Cdd:PHA02544  279 I--------RLIEIIGENNQYHGFAADQEIHLLYLLTQLM 310
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
17-265 2.32e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 90.09  E-value: 2.32e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  17 DVVGQTHVTKTLRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAI--NCLNSDDGEPCN--------ECAICKGITQGT 86
Cdd:PRK07471   20 ALFGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARFLlaTPPPGGDGAVPPptslaidpDHPVARRIAAGA 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  87 NNDVIEIDAASNNG---------VDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATT 157
Cdd:PRK07471  100 HGGLLTLERSWNEKgkrlrtvitVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSH 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 158 EPHKIPPTIISRAQRFDFKAISSDQIIDrlkyVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQ-AIAFGDERLTLQD 236
Cdd:PRK07471  180 APARLLPTIRSRCRKLRLRPLAPEDVID----ALAAAGPDLPDDPRAALAALAEGSVGRALRLAGGdGLALYRRLTALLD 255
                         250       260
                  ....*....|....*....|....*....
gi 1081111669 237 ALNvtgSVDEAALNELFNDIVKSDVKAAF 265
Cdd:PRK07471  256 TLP---RLDRRALHALADAAAGRDRAARF 281
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
32-176 1.29e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 83.53  E-value: 1.29e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  32 ISKGKQSHAYIFSGprGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGITQGTNNDVIEIdaASNNGVDEIRNIRDKV 111
Cdd:PRK07276   18 LEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVI--EPQGQVIKTDTIRELV 93
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1081111669 112 K-YAPS--ESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFK 176
Cdd:PRK07276   94 KnFSQSgyEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFP 161
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
105-170 1.95e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 79.84  E-value: 1.95e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1081111669 105 RNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRA 170
Cdd:PRK05917   81 RAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRS 146
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
28-188 5.75e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 79.08  E-value: 5.75e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  28 LRNAISKGKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDgEPCNECAICKGITQGTNND--VIEIDAASNN-GVDEI 104
Cdd:PRK06090   15 WKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQS-EACGFCHSCELMQSGNHPDlhVIKPEKEGKSiTVEQI 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 105 RNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISSDQII 184
Cdd:PRK06090   94 RQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAM 173

                  ....
gi 1081111669 185 DRLK 188
Cdd:PRK06090  174 QWLK 177
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
31-176 2.66e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 74.22  E-value: 2.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  31 AISKGKQSHAYIFSGPRGTGKTSIAkvFAKAINCLNSDDgEPCNECAICKGITQGTNNDVIEIDAASNNGVD-------- 102
Cdd:PRK08769   19 ALDAGRLGHGLLICGPEGLGKRAVA--LALAEHVLASGP-DPAAAQRTRQLIAAGTHPDLQLVSFIPNRTGDklrteivi 95
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1081111669 103 -EIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFK 176
Cdd:PRK08769   96 eQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFK 170
PRK04132 PRK04132
replication factor C small subunit; Provisional
91-229 3.48e-14

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 75.65  E-value: 3.48e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  91 IEIDAASNNGVDEIRN-IRDKVKYAP-SESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIIS 168
Cdd:PRK04132  600 LELNASDERGINVIREkVKEFARTKPiGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQS 679
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1081111669 169 RAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGD 229
Cdd:PRK04132  680 RCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAALDD 740
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
35-169 2.14e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 71.64  E-value: 2.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  35 GKQSHAYIFSGPRGTGKTSIAKVFAKAINCLNSDDGEPCNECAICKGITQGTNND--VIEIDAASNN-GVDEIRNIRDKV 111
Cdd:PRK07993   21 GRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDyyTLTPEKGKSSlGVDAVREVTEKL 100
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1081111669 112 KYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISR 169
Cdd:PRK07993  101 YEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSR 158
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
19-169 1.09e-12

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 65.63  E-value: 1.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  19 VGQTHVTKTLRNAISKGKQSHaYIFSGPRGTGKTSIAKVFAKAINclnsddgepcnecaickgitqGTNNDVIEIDAASN 98
Cdd:cd00009     1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANELF---------------------RPGAPFLYLNASDL 58
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  99 NGVDEIRNIRDKVKY-----APSESKYKVYIIDEVHMLTTGAFNALLKTLEE------PPAHAIFILATT--EPHKIPPT 165
Cdd:cd00009    59 LEGLVVAELFGHFLVrllfeLAEKAKPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNrpLLGDLDRA 138

                  ....
gi 1081111669 166 IISR 169
Cdd:cd00009   139 LYDR 142
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
8-236 1.21e-12

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 69.94  E-value: 1.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   8 RMYRPQSFDDVVGQTHVTKTLRNAIS------------KGKQSHAYIFSGPRGTGKTSIAKVFAKAINClnsddgepcne 75
Cdd:COG0464   149 LELREAILDDLGGLEEVKEELRELVAlplkrpelreeyGLPPPRGLLLYGPPGTGKTLLARALAGELGL----------- 217
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  76 caickgitqgtnnDVIEIDAAsnngvdEI---------RNIRDKVKYAPSESKYkVYIIDEVHMLTTG-----------A 135
Cdd:COG0464   218 -------------PLIEVDLS------DLvskyvgeteKNLREVFDKARGLAPC-VLFIDEADALAGKrgevgdgvgrrV 277
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 136 FNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQR-FDFKAISSDQIIDRLKYVANSQSLDyDDAALEFIAKASEGG- 213
Cdd:COG0464   278 VNTLLTEMEELRSDVVVIAATNRPDLLDPALLRRFDEiIFFPLPDAEERLEIFRIHLRKRPLD-EDVDLEELAEATEGLs 356
                         250       260
                  ....*....|....*....|....*..
gi 1081111669 214 ---MRDAL-SIMDQAIAFGDERLTLQD 236
Cdd:COG0464   357 gadIRNVVrRAALQALRLGREPVTTED 383
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
41-173 6.98e-12

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 63.00  E-value: 6.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  41 YIFSGPRGTGKTSIAKVFAKAINClnsddgepcnecaickgitqgtnnDVIEIDAAS--NNGVDE-IRNIRDKVKYAPSE 117
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGA------------------------PFIEISGSElvSKYVGEsEKRLRELFEAAKKL 56
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 118 SKyKVYIIDEVHMLTT-----------GAFNALLKTLEEPPAHA---IFILATTEPHKIPPTIISRAQRF 173
Cdd:pfam00004  57 AP-CVIFIDEIDALAGsrgsggdsesrRVVNQLLTELDGFTSSNskvIVIAATNRPDKLDPALLGRFDRI 125
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
116-188 2.04e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 65.13  E-value: 2.04e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1081111669 116 SESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFKAISSDQIIDRLK 188
Cdd:PRK07132   87 VQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILAKLL 159
PRK13341 PRK13341
AAA family ATPase;
8-186 3.13e-11

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 66.23  E-value: 3.13e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   8 RMyRPQSFDDVVGQTHVT---KTLRNAISKGKQSHAyIFSGPRGTGKTSIAKVFAKAinclnsddgepcnecaickgitq 84
Cdd:PRK13341   21 RL-RPRTLEEFVGQDHILgegRLLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANH----------------------- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  85 gTNNDVIEIDAASNnGVDEIRNirdKVKYAPSESKY----KVYIIDEVHMLTTGAFNALLKTLEEppAHAIFILATTE-P 159
Cdd:PRK13341   76 -TRAHFSSLNAVLA-GVKDLRA---EVDRAKERLERhgkrTILFIDEVHRFNKAQQDALLPWVEN--GTITLIGATTEnP 148
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1081111669 160 H-KIPPTIISRAQRFDFKAISSD---QIIDR 186
Cdd:PRK13341  149 YfEVNKALVSRSRLFRLKSLSDEdlhQLLKR 179
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
58-181 2.52e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 61.39  E-value: 2.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  58 FAKAINCLNSDdgEPCNECAICKGITQGTNNDVIEI-DAASNNGVDEIRNIRDKVKYAPSESK-YKVYIIDEVHMLTTGA 135
Cdd:PRK05818   27 YLTSIVCTKAN--GFCKTCESCLKILNGKYNDFYLIfDQKNPIKKEDALSIINKLNRPSVESNgKKIYIIYGIEKLNKQS 104
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1081111669 136 FNALLKTLEEPPAHAIFILATTEPHKIPPTIISR---------AQRFDFKAISSD 181
Cdd:PRK05818  105 ANSLLKLIEEPPKNTYGIFTTRNENNILNTILSRcvqyvvlskEKKVPFKVESND 159
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
15-277 4.45e-08

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 54.12  E-value: 4.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  15 FDDVVGQTHVTKTLRNAISKGKQ-----------SHAYIFSGPRGTGKTSIAKVFAKAINC----LNSDDgepcnecAIC 79
Cdd:COG1223     1 LDDVVGQEEAKKKLKLIIKELRRrenlrkfglwpPRKILFYGPPGTGKTMLAEALAGELKLplltVRLDS-------LIG 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  80 K--GitqgtnndvieiDAASNngvdeIRNIRDKVKYAPSeskykVYIIDEVHMLT--------TG----AFNALLKTLEE 145
Cdd:COG1223    74 SylG------------ETARN-----LRKLFDFARRAPC-----VIFFDEFDAIAkdrgdqndVGevkrVVNALLQELDG 131
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 146 PPAHAIFILATTEPHKIPPTIISraqRFD----FKAISSDQIIDRLKYVANSQSLDYdDAALEFIAKASEGgmrdalsim 221
Cdd:COG1223   132 LPSGSVVIAATNHPELLDSALWR---RFDevieFPLPDKEERKEILELNLKKFPLPF-ELDLKKLAKKLEG--------- 198
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1081111669 222 dqaIAFGD-ERLtLQDALnvtgsvdEAALNELFNDIVKSDVKAAFNRYHHFISEGKE 277
Cdd:COG1223   199 ---LSGADiEKV-LKTAL-------KKAILEDREKVTKEDLEEALKQRKERKKEPKK 244
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
11-252 8.58e-08

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 54.37  E-value: 8.58e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  11 RPQSFDDVVGQTHVTKTLRNAISKGKQ-----SHAyIFSGPRGTGKTSIAKVFAKAINclnsddgepcnecAICKgITQG 85
Cdd:PRK00080   20 RPKSLDEFIGQEKVKENLKIFIEAAKKrgealDHV-LLYGPPGLGKTTLANIIANEMG-------------VNIR-ITSG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  86 -------------TN---NDVIEIdaasnngvDEI----RNIRdkvkyapsESKYKV---YIIDevhmLTTGafnallkt 142
Cdd:PRK00080   85 palekpgdlaailTNleeGDVLFI--------DEIhrlsPVVE--------EILYPAmedFRLD----IMIG-------- 136
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 143 lEEPPAHAI------FIL--ATTEPHKIPPTIISR---AQRFDF---KAISsdQIIDRlkyvaNSQSLDY---DDAALEf 205
Cdd:PRK00080  137 -KGPAARSIrldlppFTLigATTRAGLLTSPLRDRfgiVQRLEFytvEELE--KIVKR-----SARILGVeidEEGALE- 207
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1081111669 206 IAKASEGGMRDALS----IMDQAIAFGDERLTL---QDALNVTGsVDEAALNEL 252
Cdd:PRK00080  208 IARRSRGTPRIANRllrrVRDFAQVKGDGVITKeiaDKALDMLG-VDELGLDEM 260
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
178-241 9.81e-08

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 49.06  E-value: 9.81e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1081111669 178 ISSDQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMdQAIAFGDERLTLQDALNVT 241
Cdd:cd18140     1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDL-QAAAAGGGVITEEDVYEVA 63
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
41-176 1.28e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 51.22  E-value: 1.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669   41 YIFSGPRGTGKTSIAKVFAKAINCLNSD----DGEPcnecaICKGITQGTNNDVIEIDAASNNGVDEIRNIRDKVKYaps 116
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGviyiDGED-----ILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK--- 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1081111669  117 eSKYKVYIIDEVHMLTTGAFNALL--------KTLEEPPAHAIFILATTEPHKIPPTIISRaqRFDFK 176
Cdd:smart00382  77 -LKPDVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRR--RFDRR 141
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
41-176 4.06e-07

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 49.97  E-value: 4.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  41 YIFSGPRGTGKTSIAKVFAkainclnsddGEpcnecaickgitqgTNNDVIEIDAASNNGV---DEIRNIRDKVKYApSE 117
Cdd:cd19481    29 ILLYGPPGTGKTLLAKALA----------GE--------------LGLPLIVVKLSSLLSKyvgESEKNLRKIFERA-RR 83
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1081111669 118 SKYKVYIIDEVHML------------TTGAFNALLKTLEEPPA--HAIFILATTEPHKIPPTIIsRAQRFDFK 176
Cdd:cd19481    84 LAPCILFIDEIDAIgrkrdssgesgeLRRVLNQLLTELDGVNSrsKVLVIAATNRPDLLDPALL-RPGRFDEV 155
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
181-229 1.24e-06

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 45.92  E-value: 1.24e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1081111669 181 DQIIDRLKYVANSQSLDYDDAALEFIAKASEGGMRDALSIMDQAIAFGD 229
Cdd:cd18133     4 EQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGD 52
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
116-176 1.60e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 48.88  E-value: 1.60e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1081111669 116 SESKYKVYIIdEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDFK 176
Cdd:PRK08485   52 AESEEKIIVI-AAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRK 111
PRK04132 PRK04132
replication factor C small subunit; Provisional
10-59 3.00e-06

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 50.22  E-value: 3.00e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1081111669  10 YRPQSFDDVVGQTHVTKTLRNAISKGKQSHaYIFSGPRGTGK--TSIAKVFA 59
Cdd:PRK04132   13 YRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGKclTGDTKVIA 63
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
11-60 4.33e-06

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 46.72  E-value: 4.33e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1081111669  11 RPQSFDDVVGQTHVTKTLRNAISKGKQ-----SHAyIFSGPRGTGKTSIAKVFAK 60
Cdd:pfam05496   2 RPRTLDEYIGQEKVKENLKIFIEAAKQrgealDHV-LLYGPPGLGKTTLANIIAN 55
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
96-198 5.95e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 47.92  E-value: 5.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669  96 ASNNGVDEIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPHKIPPTIISRAQRFDF 175
Cdd:PRK06581   66 AKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSRCFKINV 145
                          90       100
                  ....*....|....*....|....*..
gi 1081111669 176 K----AISSDQIIDRLKYVANSQSLDY 198
Cdd:PRK06581  146 RssilHAYNELYSQFIQPIADNKTLDF 172
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
102-259 1.39e-04

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 44.58  E-value: 1.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 102 DEIRNIRDK-VKYAPSESKYK----VYIIDEVHMLTTGAFNALLKTLEEPPAhAIFILAT---------TE---PHKIPP 164
Cdd:COG1224   270 SEVRKQVDElVKKWIEEGKAElvpgVLFIDDAHMLDIEAFSFLTRAMESELA-PIIILATnrgitkirgTDiesPHGIPL 348
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081111669 165 TIISRAQRFDFKAISSDQIIDRLKYVANSQSLDYDDAALEFIAK-ASEGGMRDALSIMDQA--IA--FGDERLTLQDaln 239
Cdd:COG1224   349 DLLDRLLIIPTRPYTEDEIREIIKIRAEEEDIELSDDALEELTKiGVERSLRYAVQLLEPAyiIAkrRGRSKVTVED--- 425
                         170       180
                  ....*....|....*....|
gi 1081111669 240 vtgsVDEAAlnELFNDIVKS 259
Cdd:COG1224   426 ----VEEAS--KLFADVKES 439
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
11-60 1.64e-04

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 43.92  E-value: 1.64e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1081111669  11 RPQSFDDVVGQTHVTKTLRNAISKGKQ-----SHAyIFSGPRGTGKTSIAKVFAK 60
Cdd:COG2255    23 RPKRLDEYIGQEKVKENLKIFIEAAKKrgealDHV-LLYGPPGLGKTTLAHIIAN 76
TIP49 pfam06068
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ...
122-170 2.86e-03

TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.


Pssm-ID: 399217 [Multi-domain]  Cd Length: 347  Bit Score: 39.99  E-value: 2.86e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1081111669 122 VYIIDEVHMLTTGAFNALLKTLEEPPAhAIFILATT------------EPHKIPPTIISRA 170
Cdd:pfam06068 277 VLFIDEVHMLDIECFSFLNRALESDLA-PIVILATNrgictirgtdiiSPHGIPLDLLDRL 336
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH