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Conserved domains on  [gi|1081125424|gb|OFS74138|]
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hypothetical protein HMPREF3167_05790 [Trueperella sp. HMSC08B05]

Protein Classification

BCCT family transporter( domain architecture ID 2807)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Escherichia coli secondary glycine betaine transporter BetU

Gene Ontology:  GO:0071705|GO:0022857|GO:0016020
PubMed:  20923416

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PRK09928 super family cl00569
choline transport protein BetT; Provisional
19-513 0e+00

choline transport protein BetT; Provisional


The actual alignment was detected with superfamily member PRK09928:

Pssm-ID: 469825  Cd Length: 679  Bit Score: 642.90  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  19 APAQRVKRTVFVGSAAIILAIAAWAFVDTGSAADALGAATGWIGQWFGWFYILMATVVVIFVLVVAFSRYGHLRLGPSDS 98
Cdd:PRK09928   10 REKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQS 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  99 RPEFSTFAWGSMLFAAGIGTDIIFFSVAEPIAQYMAPPRVAAQSLEAAEQAPVWTIFHYGLTGWGMYALMGMILGYFSYR 178
Cdd:PRK09928   90 KPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYR 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 179 HGRRLAVRSALEPVFGSRVYGVLGDVVDIAAILGTVFGVATTLGIGVVQINVGLEIIFGVGKGLPAQVALIVVAVVMAGI 258
Cdd:PRK09928  170 YNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSVIIATI 249
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 259 SAVSGVARGIKILSQLNVFLAILTVVWVLVGGRTSFLLNAIVMNVGDVLAMFPGMTLDTMAFSDADAWKAAWTLFFWAWW 338
Cdd:PRK09928  250 SVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTEWMNNWTLFFWAWW 329
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 339 VAWASFVGMFLARISRGRTLRQFIIGCLTVPFLYVAVWISIFGNAALDRVIHdDDLAFAHATLEVPEFGFYSLLEGMPAA 418
Cdd:PRK09928  330 VAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGFYSLLAQYPAF 408
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 419 RVVMMIATVVAFLFYVTSADSGSLVMANLSSDLPTPRTDARPWLRIFWAATTGVLTIGMLVVGGIPALQSATVIMGLPFA 498
Cdd:PRK09928  409 TFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFS 488
                         490
                  ....*....|....*
gi 1081125424 499 IVMVVAMMGFYRTIH 513
Cdd:PRK09928  489 FVIFFVMAGLYKSLK 503
 
Name Accession Description Interval E-value
PRK09928 PRK09928
choline transport protein BetT; Provisional
19-513 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 642.90  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  19 APAQRVKRTVFVGSAAIILAIAAWAFVDTGSAADALGAATGWIGQWFGWFYILMATVVVIFVLVVAFSRYGHLRLGPSDS 98
Cdd:PRK09928   10 REKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQS 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  99 RPEFSTFAWGSMLFAAGIGTDIIFFSVAEPIAQYMAPPRVAAQSLEAAEQAPVWTIFHYGLTGWGMYALMGMILGYFSYR 178
Cdd:PRK09928   90 KPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYR 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 179 HGRRLAVRSALEPVFGSRVYGVLGDVVDIAAILGTVFGVATTLGIGVVQINVGLEIIFGVGKGLPAQVALIVVAVVMAGI 258
Cdd:PRK09928  170 YNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSVIIATI 249
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 259 SAVSGVARGIKILSQLNVFLAILTVVWVLVGGRTSFLLNAIVMNVGDVLAMFPGMTLDTMAFSDADAWKAAWTLFFWAWW 338
Cdd:PRK09928  250 SVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTEWMNNWTLFFWAWW 329
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 339 VAWASFVGMFLARISRGRTLRQFIIGCLTVPFLYVAVWISIFGNAALDRVIHdDDLAFAHATLEVPEFGFYSLLEGMPAA 418
Cdd:PRK09928  330 VAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGFYSLLAQYPAF 408
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 419 RVVMMIATVVAFLFYVTSADSGSLVMANLSSDLPTPRTDARPWLRIFWAATTGVLTIGMLVVGGIPALQSATVIMGLPFA 498
Cdd:PRK09928  409 TFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFS 488
                         490
                  ....*....|....*
gi 1081125424 499 IVMVVAMMGFYRTIH 513
Cdd:PRK09928  489 FVIFFVMAGLYKSLK 503
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
13-518 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 553.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  13 SAPAHPAPAQRVKRTVFVGSAAIILAIAAWAFVDTGSAADALGAATGWIGQWFGWFYILMATVVVIFVLVVAFSRYGHLR 92
Cdd:COG1292     2 SDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  93 LGPSDSRPEFSTFAWGSMLFAAGIGTDIIFFSVAEPIAQYMAPPR-VAAQSLEAAEQAPVWTIFHYGLTGWGMYALMGMI 171
Cdd:COG1292    82 LGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPgVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 172 LGYFSYRHGRRLAVRSALEPVFGSRVYGVLGDVVDIAAILGTVFGVATTLGIGVVQINVGLEIIFGVGKGLPAQVALIVV 251
Cdd:COG1292   162 LAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAV 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 252 AVVMAGISAVSGVARGIKILSQLNVFLAILTVVWVLVGGRTSFLLNAIVMNVGDVLAMFPGMTLDTMAFSDADaWKAAWT 331
Cdd:COG1292   242 ITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGDTG-WLGGWT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 332 LFFWAWWVAWASFVGMFLARISRGRTLRQFIIGCLTVPFLYVAVWISIFGNAALDRVIHdDDLAFAHATLEVPEFGFYSL 411
Cdd:COG1292   321 VFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEAALFAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 412 LEGMPAARVVMMIATVVAFLFYVTSADSGSLVMANLSSDLptpRTDARPWLRIFWAATTGVLTIGMLVVGGIPALQSATV 491
Cdd:COG1292   400 LEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGG---DEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASI 476
                         490       500
                  ....*....|....*....|....*..
gi 1081125424 492 IMGLPFAIVMVVAMMGFYRTIHDDVDR 518
Cdd:COG1292   477 ITALPFSFVLLLMCVSLVKALREDPRR 503
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
28-515 6.95e-174

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 498.99  E-value: 6.95e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  28 VFVGSAAIILAIAAWAFVDTGSAADALGAATGWIGQWFGWFYILMATVVVIFVLVVAFSRYGHLRLGPSDSRPEFSTFAW 107
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 108 GSMLFAAGIGTDIIFFSVAEPIAQYMAPPRVA-AQSLEAAEQAPVWTIFHYGLTGWGMYALMGMILGYFSYRHGRRLAVR 186
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSPPPGGePGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 187 SALEPVFGSRVYGVLGDVVDIAAILGTVFGVATTLGIGVVQINVGLEIIFGVGKGLPAQVALIVVAVVMAGISAVSGVAR 266
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 267 GIKILSQLNVFLAILTVVWVLVGGRTSFLLNAIVMNVGDVLAMFPGMTLDTMAFSDADAWKAAWTLFFWAWWVAWASFVG 346
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTGGWLGGWTIFYWAWWIAWAPFVG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 347 MFLARISRGRTLRQFIIGCLTVPFLYVAVWISIFGNAALDRVIHDDDlAFAHATLEVPEFGFYSLLEGMPAARVVMMIAT 426
Cdd:pfam02028 321 MFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPG-DLADAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 427 VVAFLFYVTSADSGSLVMANLSSDLptpRTDARPWLRIFWAATTGVLTIGMLVVGGIPALQSATVIMGLPFAIVMVVAMM 506
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGG---DLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCI 476

                  ....*....
gi 1081125424 507 GFYRTIHDD 515
Cdd:pfam02028 477 SLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
66-515 1.09e-148

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 433.70  E-value: 1.09e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  66 GWFYILMATVVVIFVLVVAFSRYGHLRLGPSDSRPEFSTFAWGSMLFAAGIGTDIIFFSVAEPIAQYMAPPRVAAQ-SLE 144
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPtSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 145 AAEQAPVWTIFHYGLTGWGMYALMGMILGYFSYRHGRRLAVRSALEPVFGSRVYGVLGDVVDIAAILGTVFGVATTLGIG 224
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 225 VVQINVGLEIIFGVGKGLPAQVALIVVAVVMAGISAVSGVARGIKILSQLNVFLAILTVVWVLVGGRTSFLLNAIVMNVG 304
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 305 DVLAMFPGMTLDTMAFSDADAWKAAWTLFFWAWWVAWASFVGMFLARISRGRTLRQFIIGCLTVPFLYVAVWISIFGNAA 384
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNSA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 385 LDRVIHDDDLAFAHATLEVPEFGFYSLLEGMPAARVVMMIATVVAFLFYVTSADSGSLVMANLSSDLPTPRTDARPWLRI 464
Cdd:TIGR00842 321 LLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGGQLGEEPPKWVRV 400
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1081125424 465 FWAATTGVLTIGMLVVGG-IPALQSATVIMGLPFAIVMVVAMMGFYRTIHDD 515
Cdd:TIGR00842 401 FWAVAIGLIALVLLFSGGsLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
 
Name Accession Description Interval E-value
PRK09928 PRK09928
choline transport protein BetT; Provisional
19-513 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 642.90  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  19 APAQRVKRTVFVGSAAIILAIAAWAFVDTGSAADALGAATGWIGQWFGWFYILMATVVVIFVLVVAFSRYGHLRLGPSDS 98
Cdd:PRK09928   10 REKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQS 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  99 RPEFSTFAWGSMLFAAGIGTDIIFFSVAEPIAQYMAPPRVAAQSLEAAEQAPVWTIFHYGLTGWGMYALMGMILGYFSYR 178
Cdd:PRK09928   90 KPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYR 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 179 HGRRLAVRSALEPVFGSRVYGVLGDVVDIAAILGTVFGVATTLGIGVVQINVGLEIIFGVGKGLPAQVALIVVAVVMAGI 258
Cdd:PRK09928  170 YNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSVIIATI 249
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 259 SAVSGVARGIKILSQLNVFLAILTVVWVLVGGRTSFLLNAIVMNVGDVLAMFPGMTLDTMAFSDADAWKAAWTLFFWAWW 338
Cdd:PRK09928  250 SVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTEWMNNWTLFFWAWW 329
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 339 VAWASFVGMFLARISRGRTLRQFIIGCLTVPFLYVAVWISIFGNAALDRVIHdDDLAFAHATLEVPEFGFYSLLEGMPAA 418
Cdd:PRK09928  330 VAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGFYSLLAQYPAF 408
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 419 RVVMMIATVVAFLFYVTSADSGSLVMANLSSDLPTPRTDARPWLRIFWAATTGVLTIGMLVVGGIPALQSATVIMGLPFA 498
Cdd:PRK09928  409 TFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFS 488
                         490
                  ....*....|....*
gi 1081125424 499 IVMVVAMMGFYRTIH 513
Cdd:PRK09928  489 FVIFFVMAGLYKSLK 503
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
13-518 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 553.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  13 SAPAHPAPAQRVKRTVFVGSAAIILAIAAWAFVDTGSAADALGAATGWIGQWFGWFYILMATVVVIFVLVVAFSRYGHLR 92
Cdd:COG1292     2 SDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  93 LGPSDSRPEFSTFAWGSMLFAAGIGTDIIFFSVAEPIAQYMAPPR-VAAQSLEAAEQAPVWTIFHYGLTGWGMYALMGMI 171
Cdd:COG1292    82 LGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPgVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 172 LGYFSYRHGRRLAVRSALEPVFGSRVYGVLGDVVDIAAILGTVFGVATTLGIGVVQINVGLEIIFGVGKGLPAQVALIVV 251
Cdd:COG1292   162 LAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAV 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 252 AVVMAGISAVSGVARGIKILSQLNVFLAILTVVWVLVGGRTSFLLNAIVMNVGDVLAMFPGMTLDTMAFSDADaWKAAWT 331
Cdd:COG1292   242 ITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGDTG-WLGGWT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 332 LFFWAWWVAWASFVGMFLARISRGRTLRQFIIGCLTVPFLYVAVWISIFGNAALDRVIHdDDLAFAHATLEVPEFGFYSL 411
Cdd:COG1292   321 VFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEAALFAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 412 LEGMPAARVVMMIATVVAFLFYVTSADSGSLVMANLSSDLptpRTDARPWLRIFWAATTGVLTIGMLVVGGIPALQSATV 491
Cdd:COG1292   400 LEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGG---DEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASI 476
                         490       500
                  ....*....|....*....|....*..
gi 1081125424 492 IMGLPFAIVMVVAMMGFYRTIHDDVDR 518
Cdd:COG1292   477 ITALPFSFVLLLMCVSLVKALREDPRR 503
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
28-515 6.95e-174

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 498.99  E-value: 6.95e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  28 VFVGSAAIILAIAAWAFVDTGSAADALGAATGWIGQWFGWFYILMATVVVIFVLVVAFSRYGHLRLGPSDSRPEFSTFAW 107
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 108 GSMLFAAGIGTDIIFFSVAEPIAQYMAPPRVA-AQSLEAAEQAPVWTIFHYGLTGWGMYALMGMILGYFSYRHGRRLAVR 186
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSPPPGGePGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 187 SALEPVFGSRVYGVLGDVVDIAAILGTVFGVATTLGIGVVQINVGLEIIFGVGKGLPAQVALIVVAVVMAGISAVSGVAR 266
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 267 GIKILSQLNVFLAILTVVWVLVGGRTSFLLNAIVMNVGDVLAMFPGMTLDTMAFSDADAWKAAWTLFFWAWWVAWASFVG 346
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTGGWLGGWTIFYWAWWIAWAPFVG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 347 MFLARISRGRTLRQFIIGCLTVPFLYVAVWISIFGNAALDRVIHDDDlAFAHATLEVPEFGFYSLLEGMPAARVVMMIAT 426
Cdd:pfam02028 321 MFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPG-DLADAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 427 VVAFLFYVTSADSGSLVMANLSSDLptpRTDARPWLRIFWAATTGVLTIGMLVVGGIPALQSATVIMGLPFAIVMVVAMM 506
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGG---DLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCI 476

                  ....*....
gi 1081125424 507 GFYRTIHDD 515
Cdd:pfam02028 477 SLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
66-515 1.09e-148

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 433.70  E-value: 1.09e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  66 GWFYILMATVVVIFVLVVAFSRYGHLRLGPSDSRPEFSTFAWGSMLFAAGIGTDIIFFSVAEPIAQYMAPPRVAAQ-SLE 144
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPtSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 145 AAEQAPVWTIFHYGLTGWGMYALMGMILGYFSYRHGRRLAVRSALEPVFGSRVYGVLGDVVDIAAILGTVFGVATTLGIG 224
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 225 VVQINVGLEIIFGVGKGLPAQVALIVVAVVMAGISAVSGVARGIKILSQLNVFLAILTVVWVLVGGRTSFLLNAIVMNVG 304
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 305 DVLAMFPGMTLDTMAFSDADAWKAAWTLFFWAWWVAWASFVGMFLARISRGRTLRQFIIGCLTVPFLYVAVWISIFGNAA 384
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNSA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 385 LDRVIHDDDLAFAHATLEVPEFGFYSLLEGMPAARVVMMIATVVAFLFYVTSADSGSLVMANLSSDLPTPRTDARPWLRI 464
Cdd:TIGR00842 321 LLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGGQLGEEPPKWVRV 400
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1081125424 465 FWAATTGVLTIGMLVVGG-IPALQSATVIMGLPFAIVMVVAMMGFYRTIHDD 515
Cdd:TIGR00842 401 FWAVAIGLIALVLLFSGGsLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
59-511 8.08e-62

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 210.75  E-value: 8.08e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  59 GWIGQWF------GWFYILmatvvvifvlvvaFSRYGHLRLGpsDSRPEFSTFAWGSMLFAAGIGTDIIFFSVAEpIAQY 132
Cdd:PRK03356   52 GWAFEWYmvvmlfGWFWLV-------------FGPYAKKRLG--DEKPEFSTASWIFMMFASCTSAAVLFWGSIE-IYYY 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 133 MAPPRVAAQSL--EAAEQAPVWTIFHYGLTGWGMYALMGMILGYFSYRHgRRLAVR--SALEPVFGSR-VYGVLGDVVDI 207
Cdd:PRK03356  116 ISTPPFGLEPNstGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFFFVR-KMDVIRpsSTLVPLVGEKhAKGLFGTIVDN 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 208 AAILGTVFGVATTLGIGVVQINVGLEIIFGVGKGLPAQVALIVVAVVMAGISAVSGVARGIKILSQLNVFLAILTVVWVL 287
Cdd:PRK03356  195 FYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVF 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 288 VGGRTSFLLNAIVMNVGDVLAMFPGMTLDTMAFSdADAWKAAWTLFFWAWWVAWASFVGMFLARISRGRTLRQFIIGCLT 367
Cdd:PRK03356  275 IVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPIG-KGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVL 353
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 368 VPFLYVAVWISIFGNAALDrvihdddlAFAHATLEVPEF-----GFYSLLE---GMPAARVVMMIATVVAFLFYVTSADS 439
Cdd:PRK03356  354 GLTASTWILWTVLGSNTLL--------LMDKNIINIPNLieqygVARAIIEtwaALPLSTATMWGFFILCFIATVTLINA 425
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1081125424 440 GSLVMANLSSDLPTPRTDARPWLRIFWAATTGVLTIGMLVVGGIPALQSATVIMGLPFAIVMVVAMMGFYRT 511
Cdd:PRK03356  426 CSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKD 497
PRK09950 PRK09950
putative transporter; Provisional
50-515 2.23e-54

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 191.16  E-value: 2.23e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424  50 AADALGAATGWIGQWFGWFYILMATVVVIFVLVVAFSRYGHLRLGpsDSRPEFSTFAWGSMLFAAGIGTDIIFFSVAEPI 129
Cdd:PRK09950   34 SAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLG--EGKPEYSTLSWLFMFICAGLGSSTLYWGVMEWA 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 130 AQYMAPP-RVAAQSLEAAEQAPVWTIFHYGLTGWGMYALMGMILGY-FSYRHGRRLAVRSALEPVFGSRVYGVLGDVVDI 207
Cdd:PRK09950  112 YYYQTPGlNIAPRSPKALEYSVSYSFFHWGISAWATYALASLIMAYhFHVRKNKGLSLSGIIAAITGVKPQGPWGRLVDL 191
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 208 AAILGTVFGVATTLGIGVVQINVGLEIIFGVGKGLPAQVALIVVAVVMAGISAVSGVARGIKILSQLNVFLAILTVVWVL 287
Cdd:PRK09950  192 MFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIFCLSSYIGIDNGLQRLSKMVGWGAFLFALLVL 271
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 288 VGGRTSFLLNAIVMNVGDVLAMFPGMTLDTMAFSDAdAWKAAWTLFFWAWWVAWASFVGMFLARISRGRTLRQFIIGCLT 367
Cdd:PRK09950  272 IVGPTEFITNNIINSIGLTTQNFLQMSLFTDPMGDG-SFTRNWTVFYWLWWISYTPGVAMFVTRVSRGRKIKEVIWGLIL 350
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081125424 368 VPFLYVAVWISIFGNAALDrvihdddlAFAHATLEVP--------EFGFYSLLEGMPAARVVMMIATVVAFLFYVTSADS 439
Cdd:PRK09950  351 GSSVGCWFFFGVLESYAIH--------QFINGVINVPqilntlggETAVQQLLSSLPAGKLFLAAYLGIMIIFLASHMDA 422
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1081125424 440 GSLVMANLSSDLPTPRTDARPWLRIFWAATTGVLTIGMLVVGG-IPALQSATVIMGLPFAIVMVVAMMGFYRTIHDD 515
Cdd:PRK09950  423 VAYTMAATSTRNLREGDDPDRGLRLFWCVVITLIPLSILFTGAsLDTMKTTVVLTALPFLVILLIKVYGFIRWLKQD 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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