|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
14-820 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1451.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 14 IQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYD 93
Cdd:PRK05560 5 IIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVYD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 94 TLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLL 173
Cdd:PRK05560 85 ALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNLL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 174 MNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADeqaaLDAVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMR 253
Cdd:PRK05560 165 VNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDIT----IEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 254 GVTEIEEIGNRQVITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDESsDRVGMRIVVTLKRDAVPRVVLNNLYKHS 333
Cdd:PRK05560 241 AKAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDES-DRDGMRIVIELKRDAVPEVVLNNLYKHT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 334 QLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSPTVD 413
Cdd:PRK05560 320 QLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 414 DARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELREIVEKYGDERR 493
Cdd:PRK05560 400 EAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPRR 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 494 TQIVAATGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGAELKQDDVVKHFFICSTHDWILFFTNFGR 573
Cdd:PRK05560 480 TEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGR 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 574 VYRLKAYELPEAGRTARGQHVANLLEFQPEERIAQVIQIQSYEDAPYLVLATRDGRVKKSRLTDYESARSAGLIAINLNE 653
Cdd:PRK05560 560 VYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAINLDE 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 654 GDALIGAALAGEEDDLLLVSEQGQAIRFTADDdqLRPMGRATAGVKGMRFRGDDKLLAMTVVQDG-EFLLVATAGGYGKR 732
Cdd:PRK05560 640 GDELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVREDsQEILTVTENGYGKR 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 733 TTIEEYNTQGRGGMGVMTFKYTPKRGKLIGALAVDEEDQIFAITSAGGVIRTEVNQIRPSSRATMGVRLVDLADDVELLA 812
Cdd:PRK05560 718 TPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDKVVS 797
|
....*...
gi 1081184712 813 IDKNVEEQ 820
Cdd:PRK05560 798 VARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-813 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1342.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 1 MSDDTLGGGgsdaIQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTM 80
Cdd:COG0188 1 MSDPPPAER----IIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVM 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 81 GNFHPHGDSAIYDTLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTR 160
Cdd:COG0188 77 GKYHPHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 161 EPDVLPSRVPNLLMNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADeqaaLDAVMERVKGPDFPTAGLIVGDQGIK 240
Cdd:COG0188 157 EPTVLPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDAT----IEELMEYIPGPDFPTGGIIVGREGIR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 241 DAYTTGRGSIRMRGVTEIEEIGN-RQVITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDESsDRVGMRIVVTLKRD 319
Cdd:COG0188 233 EAYETGRGSIRVRAKAEIEELKRgREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDES-DRDGMRIVIELKRD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 320 AVPRVVLNNLYKHSQLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDAL 399
Cdd:COG0188 312 ANPEVVLNQLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNI 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 400 DEVIALIRRSPTVDDARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGN 479
Cdd:COG0188 392 DEVIAIIRASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKE 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 480 ELREIVEKYGDERRTQIVAATGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGAELKQDDVVKHFFIC 559
Cdd:COG0188 472 ELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVA 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 560 STHDWILFFTNFGRVYRLKAYELPEAGRTARGQHVANLLEFQPEERIAQVIQIQSYEDAPYLVLATRDGRVKKSRLTDYE 639
Cdd:COG0188 552 STHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFS 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 640 SARSAGLIAINLNEGDALIGAALAGEEDDLLLVSEQGQAIRFTADDdqLRPMGRATAGVKGMRFRGDDKLLAMTVVQDGE 719
Cdd:COG0188 632 NIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGMAVVDEED 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 720 FLLVATAGGYGKRTTIEEYNTQGRGGMGVMTFKYTPKRGKLIGALAVDEEDQIFAITSAGGVIRTEVNQIRPSSRATMGV 799
Cdd:COG0188 710 DLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGV 789
|
810
....*....|....
gi 1081184712 800 RLVDLADDVELLAI 813
Cdd:COG0188 790 RLIRLDEGDKVVSV 803
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
129-819 |
0e+00 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 1315.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 129 TECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLLMNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYD 208
Cdd:NF038098 538 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWCLDNPE 617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 209 ADEQAALDAVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMRGVTEIEEIGN-RQVITITELPYQVNPDNFIHNIAE 287
Cdd:NF038098 618 ADEEETLAAVMERVKGPDFPTHGLIVGTQGIEDAYRTGRGSIRMRGVVEVEEDARgRTSLVITELPYQVNPDNLIESIAE 697
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 288 QVTAGKMVGISKIEDESSDRVGMRIVVTLKRDAVPRVVLNNLYKHSQLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQ 367
Cdd:NF038098 698 QVRDGKLAGISNIEDESSDRVGMRIVVELKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQMIRHYVDHQ 777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 368 IDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSPTVDDARQGLIKLLDVDEIQANEILAMQLRRLAALERQ 447
Cdd:NF038098 778 LDVIVRRTRYRLRKAEERAHILRGLVKALDALDEVIALIRASPTVDVARTGLIELLDVDEIQAQAILDMQLRRLAALERQ 857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 448 KIVDDLAEIERKIADYKDILARPERQREIVGNELREIVEKYGDERRTQIVAATGDVTEEDLIARENVVVTITSTGYAKRT 527
Cdd:NF038098 858 RIIDDLAKIEAEIADLEDILAKPERQRAIVRDELKEIVDKYGDDRRTRIIPADGDVSDEDLIAREDVVVTITETGYAKRT 937
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 528 KVDAYKSQKRGGKGVRGAELKQDDVVKHFFICSTHDWILFFTNFGRVYRLKAYELPEAGRTARGQHVANLLEFQPEERIA 607
Cdd:NF038098 938 KTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDWILFFTNKGRVYRAKAYELPEASRTARGQHVANLLAFQPDERIA 1017
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 608 QVIQIQSYEDAPYLVLATRDGRVKKSRLTDYESARSAGLIAINLNEGDALIGAALAGEEDDLLLVSEQGQAIRFTADDDQ 687
Cdd:NF038098 1018 QVIQIKDYEDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAINLRDGDELVGAVLCSAEDDLLLVSAKGQSIRFSATDEA 1097
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 688 LRPMGRATAGVKGMRFRGDDKLLAMTVVQDGEFLLVATAGGYGKRTTIEEYNTQGRGGMGVMTFKYTPKRGKLIGALAVD 767
Cdd:NF038098 1098 LRPMGRATSGVQGMRFNEDDELLSLNVVREGTYLLVATSGGYAKRTPIEEYPVQGRGGKGVLTIQYDRRRGRLVGALIVD 1177
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 1081184712 768 EEDQIFAITSAGGVIRTEVNQIRPSSRATMGVRLVDLADDVELLAIDKNVEE 819
Cdd:NF038098 1178 DDDELYAITSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNADE 1229
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
14-818 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1186.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 14 IQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYD 93
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 94 TLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLL 173
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 174 MNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADEQaaldAVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMR 253
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQ----ELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 254 GVTEIEEIGN-RQVITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDEsSDRVGMRIVVTLKRDAVPRVVLNNLYKH 332
Cdd:TIGR01063 237 ARAEIEEDSKgREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDE-SDREGIRIVIELKRDAVAEVVLNNLYKQ 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 333 SQLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSPTV 412
Cdd:TIGR01063 316 TQLQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 413 DDARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELREIVEKYGDER 492
Cdd:TIGR01063 396 EEAKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 493 RTQIVAATGDVTE-EDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGAELKQDDVVKHFFICSTHDWILFFTNF 571
Cdd:TIGR01063 476 RTEIVYDESEDIDiEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNR 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 572 GRVYRLKAYELPEAGRTARGQHVANLLEFQPEERIAQVIQIQSYEDAPYLVLATRDGRVKKSRLTDYESARSAGLIAINL 651
Cdd:TIGR01063 556 GKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 652 NEGDALIGAALAGEEDDLLLVSEQGQAIRFTADDdqLRPMGRATAGVKGMRFRGDDKLLAMTVVQDGEFLLVATAGGYGK 731
Cdd:TIGR01063 636 DDGDELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEESYLLIVTENGYGK 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 732 RTTIEEYNTQGRGGMGVMTFKYTPKRGKLIGALAVDEEDQIFAITSAGGVIRTEVNQIRPSSRATMGVRLVDLADDVELL 811
Cdd:TIGR01063 714 RTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLV 793
|
....*..
gi 1081184712 812 AIDKNVE 818
Cdd:TIGR01063 794 SVSKVAK 800
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
36-484 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 635.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 36 VGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYDTLVRMAQPWAMRYPLVDGQGNF 115
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 116 GSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLLMNGSNGIAVGMATNIPPHNLNE 195
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 196 LAEAIYWMLDNydadEQAALDAVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMRGVTEIEEIGNRQVITITELPYQ 275
Cdd:cd00187 161 VIDALRALIDN----PEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 276 VNPDNFIHNIAEQVTAGKMVGISKIEDEsSDRVGMRIVVTLKRDAVPRVVLNNLYKHSQLETNFSANMLSIV-DGVPRTL 354
Cdd:cd00187 237 VNKAKLKEKIAELVKDKKIEGISDVRDE-SDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 355 RLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSptvDDARQGLIKLLDV---DEIQAN 431
Cdd:cd00187 316 NLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELEKlgfSEIQAD 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1081184712 432 EILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELREI 484
Cdd:cd00187 393 AILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
17-474 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 601.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 17 IDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYDTLV 96
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 97 RMAQPWAMRYPLVDGQGNFGSP-GNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLLMN 175
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 176 GSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADeqaaLDAVMERVKGPDFPTAGLIVgdqgikdayttGRGSIRMRGV 255
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDAS----IDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 256 TEIEEignRQVITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDESSDRVGMRIVVTLKRDAVPRVVLNNLYKHSQL 335
Cdd:smart00434 226 IEIED---DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 336 ETNFSANMLSIVD-GVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAE-KRAHILRGLVKALDALDEVIALIRRSP-TV 412
Cdd:smart00434 303 QTTFSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKdLA 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1081184712 413 DDARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQR 474
Cdd:smart00434 383 KEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
38-482 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 577.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 38 RALPDVRDGMKPVHRRIIYAMYDhGYRPERSYVKSAKPVADTMGNFHPHGDSAIYDTLVRMAQPWAMRYPLVDGQGNFGS 117
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFE-LLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 118 -PGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLLMNGSNGIAVGMATNIPPHNLNEL 196
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 197 AEAIYWMLDNYDADEqaaldaVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMRGVTEIEEignRQVITITELPYQV 276
Cdd:pfam00521 160 IDALIALLDGPEATL------LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED---RKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 277 NPDNFIHNIAEQVTAGKMVGISKIEDEsSDRvGMRIVVTLKRDAVPRVVLNNLYKHSQLETNFSANMLSIVDGVPRTLRL 356
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDE-SDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 357 DQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSPTVDDARQGLIKllDVDEIQANEILAM 436
Cdd:pfam00521 309 KEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDM 386
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1081184712 437 QLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELR 482
Cdd:pfam00521 387 RLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
14-128 |
9.89e-76 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 268.90 E-value: 9.89e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 14 IQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYD 93
Cdd:NF038098 2 IEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYD 81
|
90 100 110
....*....|....*....|....*....|....*
gi 1081184712 94 TLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRY 128
Cdd:NF038098 82 TLVRMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
14-820 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1451.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 14 IQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYD 93
Cdd:PRK05560 5 IIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVYD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 94 TLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLL 173
Cdd:PRK05560 85 ALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNLL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 174 MNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADeqaaLDAVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMR 253
Cdd:PRK05560 165 VNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDIT----IEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 254 GVTEIEEIGNRQVITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDESsDRVGMRIVVTLKRDAVPRVVLNNLYKHS 333
Cdd:PRK05560 241 AKAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDES-DRDGMRIVIELKRDAVPEVVLNNLYKHT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 334 QLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSPTVD 413
Cdd:PRK05560 320 QLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 414 DARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELREIVEKYGDERR 493
Cdd:PRK05560 400 EAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPRR 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 494 TQIVAATGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGAELKQDDVVKHFFICSTHDWILFFTNFGR 573
Cdd:PRK05560 480 TEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGR 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 574 VYRLKAYELPEAGRTARGQHVANLLEFQPEERIAQVIQIQSYEDAPYLVLATRDGRVKKSRLTDYESARSAGLIAINLNE 653
Cdd:PRK05560 560 VYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAINLDE 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 654 GDALIGAALAGEEDDLLLVSEQGQAIRFTADDdqLRPMGRATAGVKGMRFRGDDKLLAMTVVQDG-EFLLVATAGGYGKR 732
Cdd:PRK05560 640 GDELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVREDsQEILTVTENGYGKR 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 733 TTIEEYNTQGRGGMGVMTFKYTPKRGKLIGALAVDEEDQIFAITSAGGVIRTEVNQIRPSSRATMGVRLVDLADDVELLA 812
Cdd:PRK05560 718 TPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDKVVS 797
|
....*...
gi 1081184712 813 IDKNVEEQ 820
Cdd:PRK05560 798 VARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-813 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1342.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 1 MSDDTLGGGgsdaIQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTM 80
Cdd:COG0188 1 MSDPPPAER----IIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVM 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 81 GNFHPHGDSAIYDTLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTR 160
Cdd:COG0188 77 GKYHPHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 161 EPDVLPSRVPNLLMNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADeqaaLDAVMERVKGPDFPTAGLIVGDQGIK 240
Cdd:COG0188 157 EPTVLPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDAT----IEELMEYIPGPDFPTGGIIVGREGIR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 241 DAYTTGRGSIRMRGVTEIEEIGN-RQVITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDESsDRVGMRIVVTLKRD 319
Cdd:COG0188 233 EAYETGRGSIRVRAKAEIEELKRgREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDES-DRDGMRIVIELKRD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 320 AVPRVVLNNLYKHSQLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDAL 399
Cdd:COG0188 312 ANPEVVLNQLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNI 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 400 DEVIALIRRSPTVDDARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGN 479
Cdd:COG0188 392 DEVIAIIRASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKE 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 480 ELREIVEKYGDERRTQIVAATGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGAELKQDDVVKHFFIC 559
Cdd:COG0188 472 ELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVA 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 560 STHDWILFFTNFGRVYRLKAYELPEAGRTARGQHVANLLEFQPEERIAQVIQIQSYEDAPYLVLATRDGRVKKSRLTDYE 639
Cdd:COG0188 552 STHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFS 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 640 SARSAGLIAINLNEGDALIGAALAGEEDDLLLVSEQGQAIRFTADDdqLRPMGRATAGVKGMRFRGDDKLLAMTVVQDGE 719
Cdd:COG0188 632 NIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGMAVVDEED 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 720 FLLVATAGGYGKRTTIEEYNTQGRGGMGVMTFKYTPKRGKLIGALAVDEEDQIFAITSAGGVIRTEVNQIRPSSRATMGV 799
Cdd:COG0188 710 DLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGV 789
|
810
....*....|....
gi 1081184712 800 RLVDLADDVELLAI 813
Cdd:COG0188 790 RLIRLDEGDKVVSV 803
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
129-819 |
0e+00 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 1315.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 129 TECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLLMNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYD 208
Cdd:NF038098 538 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWCLDNPE 617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 209 ADEQAALDAVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMRGVTEIEEIGN-RQVITITELPYQVNPDNFIHNIAE 287
Cdd:NF038098 618 ADEEETLAAVMERVKGPDFPTHGLIVGTQGIEDAYRTGRGSIRMRGVVEVEEDARgRTSLVITELPYQVNPDNLIESIAE 697
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 288 QVTAGKMVGISKIEDESSDRVGMRIVVTLKRDAVPRVVLNNLYKHSQLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQ 367
Cdd:NF038098 698 QVRDGKLAGISNIEDESSDRVGMRIVVELKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQMIRHYVDHQ 777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 368 IDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSPTVDDARQGLIKLLDVDEIQANEILAMQLRRLAALERQ 447
Cdd:NF038098 778 LDVIVRRTRYRLRKAEERAHILRGLVKALDALDEVIALIRASPTVDVARTGLIELLDVDEIQAQAILDMQLRRLAALERQ 857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 448 KIVDDLAEIERKIADYKDILARPERQREIVGNELREIVEKYGDERRTQIVAATGDVTEEDLIARENVVVTITSTGYAKRT 527
Cdd:NF038098 858 RIIDDLAKIEAEIADLEDILAKPERQRAIVRDELKEIVDKYGDDRRTRIIPADGDVSDEDLIAREDVVVTITETGYAKRT 937
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 528 KVDAYKSQKRGGKGVRGAELKQDDVVKHFFICSTHDWILFFTNFGRVYRLKAYELPEAGRTARGQHVANLLEFQPEERIA 607
Cdd:NF038098 938 KTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDWILFFTNKGRVYRAKAYELPEASRTARGQHVANLLAFQPDERIA 1017
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 608 QVIQIQSYEDAPYLVLATRDGRVKKSRLTDYESARSAGLIAINLNEGDALIGAALAGEEDDLLLVSEQGQAIRFTADDDQ 687
Cdd:NF038098 1018 QVIQIKDYEDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAINLRDGDELVGAVLCSAEDDLLLVSAKGQSIRFSATDEA 1097
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 688 LRPMGRATAGVKGMRFRGDDKLLAMTVVQDGEFLLVATAGGYGKRTTIEEYNTQGRGGMGVMTFKYTPKRGKLIGALAVD 767
Cdd:NF038098 1098 LRPMGRATSGVQGMRFNEDDELLSLNVVREGTYLLVATSGGYAKRTPIEEYPVQGRGGKGVLTIQYDRRRGRLVGALIVD 1177
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 1081184712 768 EEDQIFAITSAGGVIRTEVNQIRPSSRATMGVRLVDLADDVELLAIDKNVEE 819
Cdd:NF038098 1178 DDDELYAITSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNADE 1229
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
14-818 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1186.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 14 IQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYD 93
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 94 TLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLL 173
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 174 MNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADEQaaldAVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMR 253
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQ----ELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 254 GVTEIEEIGN-RQVITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDEsSDRVGMRIVVTLKRDAVPRVVLNNLYKH 332
Cdd:TIGR01063 237 ARAEIEEDSKgREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDE-SDREGIRIVIELKRDAVAEVVLNNLYKQ 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 333 SQLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSPTV 412
Cdd:TIGR01063 316 TQLQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 413 DDARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELREIVEKYGDER 492
Cdd:TIGR01063 396 EEAKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 493 RTQIVAATGDVTE-EDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGAELKQDDVVKHFFICSTHDWILFFTNF 571
Cdd:TIGR01063 476 RTEIVYDESEDIDiEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNR 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 572 GRVYRLKAYELPEAGRTARGQHVANLLEFQPEERIAQVIQIQSYEDAPYLVLATRDGRVKKSRLTDYESARSAGLIAINL 651
Cdd:TIGR01063 556 GKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 652 NEGDALIGAALAGEEDDLLLVSEQGQAIRFTADDdqLRPMGRATAGVKGMRFRGDDKLLAMTVVQDGEFLLVATAGGYGK 731
Cdd:TIGR01063 636 DDGDELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEESYLLIVTENGYGK 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 732 RTTIEEYNTQGRGGMGVMTFKYTPKRGKLIGALAVDEEDQIFAITSAGGVIRTEVNQIRPSSRATMGVRLVDLADDVELL 811
Cdd:TIGR01063 714 RTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLV 793
|
....*..
gi 1081184712 812 AIDKNVE 818
Cdd:TIGR01063 794 SVSKVAK 800
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
11-749 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 848.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 11 SDAIQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSA 90
Cdd:PRK05561 7 LEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHGDSS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 91 IYDTLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVP 170
Cdd:PRK05561 87 IYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPARFP 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 171 NLLMNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADeqaaLDAVMERVKGPDFPTAGLIVGD-QGIKDAYTTGRGS 249
Cdd:PRK05561 167 NLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDAT----LEELMEFVPGPDFPTGGEIITGrDGIRKAYETGRGS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 250 IRMRGVTEIEEI-GNRQVITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDESSDRVGMRIVVTLKRDAV-PRVVLN 327
Cdd:PRK05561 243 IRVRARWEIEDLaGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENPVRIVIEPKSNRVdPEALMN 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 328 NLYKHSQLETNFSANMLSI-VDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALI 406
Cdd:PRK05561 323 HLFATTDLESSYRVNMNAIgLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRII 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 407 RRSptvDDARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELREIVE 486
Cdd:PRK05561 403 RES---DEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAK 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 487 KYGDERRTQIVAATGDV--TEEDLIARENVVVTITSTGYAKRTKvdayksqkrgGKGVRGAEL--KQDDVVKHFFICSTH 562
Cdd:PRK05561 480 KFGDPRRTPIEEAEEAIaiDEEALIPDEPVTVVLSKKGWVRRAK----------GHSIDASGLsfKEGDSLLFAFEARTT 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 563 DWILFFTNFGRVYRLKAYELPEagrtAR--GQHVANLLEFQPEERIAQVIqiqSYEDAPYLVLATRDGRVKKSRLTDYES 640
Cdd:PRK05561 550 DKLLLFTSTGRVYSLPVHELPS----ARgdGEPLTGLVDLAPGEEIVHVL---AFDPDQKLLLASSAGYGFVVTLEDLVA 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 641 ARSAGLIAINLNEGDALIGAALAGEEDDLLLVSEQGQAIRFTAddDQLRPMGRAtAGVKGMRFR-GDDKLLAMTVVQDGE 719
Cdd:PRK05561 623 RTRAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPL--SELPELGKG-KGVKLINLPkDDDGLVDLRVLNPED 699
|
730 740 750
....*....|....*....|....*....|...
gi 1081184712 720 FLLVATAGGYGKRTT---IEEYNTQgRGGMGVM 749
Cdd:PRK05561 700 GLVLLTAGKRKLKLKpseLEKYRGK-RARRGRL 731
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
36-484 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 635.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 36 VGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYDTLVRMAQPWAMRYPLVDGQGNF 115
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 116 GSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLLMNGSNGIAVGMATNIPPHNLNE 195
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 196 LAEAIYWMLDNydadEQAALDAVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMRGVTEIEEIGNRQVITITELPYQ 275
Cdd:cd00187 161 VIDALRALIDN----PEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 276 VNPDNFIHNIAEQVTAGKMVGISKIEDEsSDRVGMRIVVTLKRDAVPRVVLNNLYKHSQLETNFSANMLSIV-DGVPRTL 354
Cdd:cd00187 237 VNKAKLKEKIAELVKDKKIEGISDVRDE-SDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 355 RLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSptvDDARQGLIKLLDV---DEIQAN 431
Cdd:cd00187 316 NLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELEKlgfSEIQAD 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1081184712 432 EILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELREI 484
Cdd:cd00187 393 AILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
17-474 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 601.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 17 IDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYDTLV 96
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 97 RMAQPWAMRYPLVDGQGNFGSP-GNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLLMN 175
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 176 GSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADeqaaLDAVMERVKGPDFPTAGLIVgdqgikdayttGRGSIRMRGV 255
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDAS----IDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 256 TEIEEignRQVITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDESSDRVGMRIVVTLKRDAVPRVVLNNLYKHSQL 335
Cdd:smart00434 226 IEIED---DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 336 ETNFSANMLSIVD-GVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAE-KRAHILRGLVKALDALDEVIALIRRSP-TV 412
Cdd:smart00434 303 QTTFSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKdLA 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1081184712 413 DDARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQR 474
Cdd:smart00434 383 KEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
14-822 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 577.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 14 IQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYD 93
Cdd:PRK13979 13 IIKIPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 94 TLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLL 173
Cdd:PRK13979 93 AMVILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 174 MNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADEQaaldAVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMR 253
Cdd:PRK13979 173 VNGAFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTK----ELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLR 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 254 GVTEIEEIGN-RQVITITELPYQVNPDNFIHNIAEqVTAGK-----MVGISKIEDEsSDRVGMRIVVTLKRDA---VPRV 324
Cdd:PRK13979 249 AKTKIEKLENgRLGIVITEFPYRRNKAKLLQTISE-MTADKkhskaLENISDIRDE-SDRNGIRAVIEFKKSAdedVAEK 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 325 VLNNLYKHSQLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIA 404
Cdd:PRK13979 327 VLKYLYKKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIK 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 405 LIRRSPTVDDARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELREI 484
Cdd:PRK13979 407 TIRSSKSKKDASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEV 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 485 VEKYGDERRTQIV----AATGDVteEDLIARENVVVTITSTGYAKRTKVdayKSQKRGGKGVRGAELKQDDVVKHFFICS 560
Cdd:PRK13979 487 KEKYGDERRTSIIeddeKAKIDV--EELIVVEDVVITLSNEGFIKRIPL---KSYNRSNSNVEDIEYREGDFNKFLIQSN 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 561 THDWILFFTNFGRVYRLKAYELPEAGRTARGQHVANL-----LEfqpEERIAQVIQIQSYEDAPYLVLATRDGRVKKSRL 635
Cdd:PRK13979 562 TKDTLLIFTDKGNMYQIKGINIPEFKWKEKGERLDEIikgidLE---SEKIIEAYSIEDFTPQKDFIFITDSGGIKKTSL 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 636 TDYESARSAgLIAINLNEGDALIGAALA--GEEDDLLLVSEQgQAIRFTADDDQLRPMGRATAGVKGMRFRGDDKLLAMT 713
Cdd:PRK13979 639 DKFVTNYTK-LMALKLKKGEKLIKVKLVdrTREEKFIKIKTK-KGLSFTVEEPELEPVDRNIIGYQLFDLLPNDSIKKVD 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 714 VVQDGEFLLVATagGYGKRTTIEEYNTQGRGGMGVMT------------------------------------FKYTPKR 757
Cdd:PRK13979 717 FCDNYEYKEFYV--NINKKGIIKISDKDNKSSISVFTnssknllifsdegkvykipafmlqnikneginisalTGDFEKD 794
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1081184712 758 GKLIGALAV---DEEDQIFAITSAGGVIRTEVNQIRPSSRATMGVRLVDlaDDVELLAIDKNVEEQGE 822
Cdd:PRK13979 795 EKIIKIISIfefEEDLSIYFFSKKGLVKKTLLNEFKGEGNSTQAYKFKH--KEDELVNVDIKEHEEKN 860
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
38-482 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 577.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 38 RALPDVRDGMKPVHRRIIYAMYDhGYRPERSYVKSAKPVADTMGNFHPHGDSAIYDTLVRMAQPWAMRYPLVDGQGNFGS 117
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFE-LLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 118 -PGNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNLLMNGSNGIAVGMATNIPPHNLNEL 196
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 197 AEAIYWMLDNYDADEqaaldaVMERVKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMRGVTEIEEignRQVITITELPYQV 276
Cdd:pfam00521 160 IDALIALLDGPEATL------LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED---RKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 277 NPDNFIHNIAEQVTAGKMVGISKIEDEsSDRvGMRIVVTLKRDAVPRVVLNNLYKHSQLETNFSANMLSIVDGVPRTLRL 356
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDE-SDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 357 DQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRSPTVDDARQGLIKllDVDEIQANEILAM 436
Cdd:pfam00521 309 KEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDM 386
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1081184712 437 QLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELR 482
Cdd:pfam00521 387 RLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
14-758 |
1.59e-161 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 488.26 E-value: 1.59e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 14 IQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYD 93
Cdd:TIGR01062 1 IENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 94 TLVRMAQPWAMRYPLVDGQGNFGSP-GNDGPAAMRYTECKMTPLAMEMVRDIREDAVEFSPNYDGKTREPDVLPSRVPNL 172
Cdd:TIGR01062 81 AMVLMAQPFSYRYPLVDGQGNWGAPdDPKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 173 LMNGSNGIAVGMATNIPPHNLNELAEAIYWMLDNydadEQAALDAVMERVKGPDFPTAGLIVGDQG-IKDAYTTGRGSIR 251
Cdd:TIGR01062 161 LLNGTTGIAVGMATDIPPHNLHELADAALYLIDN----PKAGLDDILNIVQGPDFPTEAEIIDKAEeIRKIYETGRGSFR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 252 MRGVTEIEEIGnrqvITITELPYQVNPDNFIHNIAEQVTAGKMVGISKIEDESSDRVGMRIVVTLKRDAV-PRVVLNNLY 330
Cdd:TIGR01062 237 MRARWKKEDGQ----IVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENPIRVVIVPRSNRVdPDIVMEHLF 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 331 KHSQLETNFSANMLSI-VDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDALDEVIALIRRS 409
Cdd:TIGR01062 313 ATTDLEKSYRLNMNMIgLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREE 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 410 ptvDDARQGLIKLLDVDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARPERQREIVGNELREIVEKYG 489
Cdd:TIGR01062 393 ---DEPKTILMERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYG 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 490 DERRTQI--VAATGDVTEEDLIARENVVVTITSTGYAkrtkvdayKSQKRGGKGVRGAELKQDDVVKHFFICSTHDWILF 567
Cdd:TIGR01062 470 LARRSSLeeREEAKQVSEIDMIPKEPVTIILSKMGWV--------RSAKGHDIDLSTLKYKAGDSEKAIIEGKSNQKVVF 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 568 FTNFGRVYRLKAYELPEAgrTARGQHVANLLEFQPEERIAQVIQiqsYEDAPYLVLATRDGRVKKSRLTDYESARSAGLI 647
Cdd:TIGR01062 542 IDSTGRSYALDPDNLPSA--RGQGEPLTGKLLLPIGATITNILM---YSPNQLLLMASDAGYGFLCNFNDLIARNKAGKA 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 648 AINLNEGDALIGA-ALAGEEDDLLLVSEQGQAIRFTADDdqlRPMGRATAGVKGMRF------RGDDKLLAMTVVQDGEF 720
Cdd:TIGR01062 617 LINLPENASVIAPlPVNGDSDMIAAITEAGRMLVFPIDD---LPELSKGKGNKLIRIpsanakRGEDGLLDLKIFNKQDG 693
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 1081184712 721 LLVATaggyGKRTTIEEYN-----TQGRGGMGVmtfkyTPKRG 758
Cdd:TIGR01062 694 LSWND----GKRKIQLEPEelqkfLGERGRFGT-----TLPRG 727
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
14-128 |
9.89e-76 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 268.90 E-value: 9.89e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 14 IQPIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVADTMGNFHPHGDSAIYD 93
Cdd:NF038098 2 IEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYD 81
|
90 100 110
....*....|....*....|....*....|....*
gi 1081184712 94 TLVRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRY 128
Cdd:NF038098 82 TLVRMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
16-523 |
3.28e-68 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 238.45 E-value: 3.28e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 16 PIDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMY--DHGyrperSYVKSAKPVADTMgNFHPHGDSAIYD 93
Cdd:PRK09631 1 MMDIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFemHDG-----KFHKVANVVGNTM-KYHPHGDASIYE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 94 TLVRMAQpwamRYPLVDGQGNFGSPGNDGPA-AMRYTECKMTPLAMEMVrdIREDAVEFSPNYDGKTREPDVLPSRVPNL 172
Cdd:PRK09631 75 ALVNLAN----KDLFIDKQGNFGNLFTGDPAsAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 173 LMNGSNGIAVGMATNIPPHNLNELAEAIYWMLDnydaDEQAALdavmervkGPDFPTAGLI-VGDqgikdaYTTGRGSIR 251
Cdd:PRK09631 149 LIQGAEGIAVGMATKILPHNFNEILQAVKSELL----GESFAL--------YPDFPTGGIVdVSE------YADGNGKVL 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 252 MRGvtEIEEIgNRQVITITELPYQVNPDNFIHNIAEQVTAGKmVGISKIEDESSDRVgmRIVVTLKRDAVPRVVLNNLYK 331
Cdd:PRK09631 211 VRA--KIETK-DEKTIVIREIPFGTTTESLIASIEKAARKGK-IKISSINDYTAENV--EIEIKLPRGVYASEVIEALYA 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 332 HSQLETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAH--------ILRGLVKALDAL---D 400
Cdd:PRK09631 285 YTDCEVSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELERAKLLEKIFaktleqifIEERIYKRIETIsseE 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 401 EVIAlirrspTVDDA----RQGLIKLLDVDEIQanEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILarperqREI 476
Cdd:PRK09631 365 DVIS------IVLSElkpfKEELSRDVTEEDIE--NLLKIPIRRISLFDIDKNQKEIRILNKELKSVEKNL------KSI 430
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 1081184712 477 VG---NELREIVEKYGDE--RRTQIVAATGDVTEEdlIARENVVVTIT-STGY 523
Cdd:PRK09631 431 KGyaiNFIDKLLAKYSKEypRKTEISLIKSVDVRE--IATKNLKVYYDlKTGF 481
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
27-496 |
1.61e-60 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 221.03 E-value: 1.61e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 27 YIDYAMSVIVGRALPDVRDGMKPVHRRIIYAM--YDHGyrperSYVKSAKPVADTMgNFHPHGDSAIYDTLVRMAQpwam 104
Cdd:PRK12758 31 FLDYASYVILERAVPHIEDGLKPVQRRILHSMkeMDDG-----RYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ---- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 105 RYPLVDGQGNFGSP-GNDGPAAMRYTECKMTPLAMEMVrdIREDAVEFSPNYDGKTREPDVLPSRVPNLLMNGSNGIAVG 183
Cdd:PRK12758 101 KDLLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAVG 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 184 MATNIPPHNLNELaeaiywmldnydadeqaaLDAVMERVKG------PDFPTAGLI-VGDqgikdaYTTGR--GSIRMRG 254
Cdd:PRK12758 179 LSTKILPHNFNEL------------------IDASIAYLKGkefklyPDFPTGGIIdVSN------YNDGErgGRVRVRA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 255 vtEIEEIGNRqVITITELPYQVNPDNFIHNIAEQVTAGKmVGISKIEDESSDRVgmRIVVTLKRDAVPRVVLNNLYKHSQ 334
Cdd:PRK12758 235 --KIEKLDKK-TLVITEIPYGTTTSSLIDSILKANDKGK-IKIKKVEDNTAADV--EILVHLAPGVSPDKTIDALYAFTD 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 335 LETNFSANMLSIVDGVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAH------------ILRGLVKALDaLDEV 402
Cdd:PRK12758 309 CEVSISPNACVIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHfaslekifieerIYKEIEEAET-WEAV 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 403 IALIR-----------RSPTVDDarqgLIKLLDVdeiqaneilamQLRRLAALERQKIVDDLAEIERKIADYKDILArpe 471
Cdd:PRK12758 388 IEAIDkglepfkkqfiREVTEDD----IVRLTEI-----------KIKRISKFDSDKADELIARLEAEIAEVKHHLA--- 449
|
490 500 510
....*....|....*....|....*....|
gi 1081184712 472 rqrEIVG---NELREIVEKYGD--ERRTQI 496
Cdd:PRK12758 450 ---HLTDyaiAYFTNLKKKYGKgrERKTEI 476
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
18-496 |
1.61e-52 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 190.88 E-value: 1.61e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 18 DINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMY--DHGyrperSYVKSAKPVADTMGnFHPHGDSAIYDTL 95
Cdd:PRK09630 3 DVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFrmDDG-----KMHKVANIAGRTMA-LHPHGDAPIVEAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 96 VRMAQpwamRYPLVDGQGNFGSPGNDGP-AAMRYTECKMTPLAMEMVrdIREDAVEFSPNYDGKTREPDVLPSRVPNLLM 174
Cdd:PRK09630 77 VVLAN----KGYLIDTQGNFGNPLTGDPhAAARYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAKLPLLLL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 175 NGSNGIAVGMATNIPPHNLNELAEAIYWMLDNydadeqAALDAVmervkgPDFPTAGLIvgdqgikDA--YTTGRGSIRM 252
Cdd:PRK09630 151 HGVDGIAVGMTTKIFPHNFCELLEAQIAILND------QPFTLL------PDFPSGGTM-------DAseYQDGLGSITL 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 253 RGVTEIEeigNRQVITITELPYQVNPDNFIHNIAEQVTAGkMVGISKIEDESSDRVgmRIVVTLKRDAVPRVVLNNLYKH 332
Cdd:PRK09630 212 RASIDII---NDKTLLIKEICPSTTTETLIRSIENAAKRG-IIKIDSIQDFSTDLP--HIEIKLPKGIYAKDLLRPLFTH 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 333 SQLETNFSANMLSIVDGVPRTLRLDQMLRYYVKhQIDVIVRRTKFRLDEAEKRAHILRGLV------KALDALDEVIALI 406
Cdd:PRK09630 286 TECQVILTSRPTAIYQNKPVETSISEILRLHTE-TLQGYLKKELLILEDSLSREHYHKTLEyifikhKLYDTVREMLSKR 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 407 RRSPTVDDARQGLIKLLD---------VDEIQANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILArpeRQREIV 477
Cdd:PRK09630 365 KTSPSSSDLHNAVLEALTpfldtlptpVDKQATAQLASLTIKKILCFNENSYTKELACIEKKQAAVQKDLS---QLKKYT 441
|
490 500
....*....|....*....|.
gi 1081184712 478 GNELREIVEKYGD--ERRTQI 496
Cdd:PRK09630 442 VKYLKGLLETYGQlgHRKTQI 462
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
17-457 |
2.34e-43 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 163.30 E-value: 2.34e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 17 IDINEEMQTSYIDYAMSVIVGRALPDVRDGMKPVHRRIIYAMYDHGYRPERSYVKSAKPVAD-TMGNFHpHGDSAIYDTL 95
Cdd:PHA02592 6 RSLKSIVNNEALEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGvADLGYH-HGETSAQDAG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 96 VRMAQPWAMRYPLVDGQGNFGSPGNDGPAAMRYTECKMTPLAMEMVRDIredavEFSPNY-DGKTREPDVLPSRVPNLLM 174
Cdd:PHA02592 85 ALMANTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARVHDNFRKIYKDE-----DLAPVHeDPEHIPPAFYLPIIPMVLL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 175 NGSNGIAVGMATNIPPHNLNELAEAIYWMLDNYDADEQaaldavmeRVKGPDFptAGLIVgdqgikdayTTGRGSIRMRG 254
Cdd:PHA02592 160 NGVSGIATGYATNILPHSPKSVIKAVLAALNGKDITEP--------KVQFPEF--KGEVV---------EIEPGSYEIRG 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 255 vteIEEIGNRQVITITELPYQVNPDNFIHNIAEQVTAGKmvgISKIEDESSDrvGMRIVVTLKRDAVPRVVLNNLYKHSQ 334
Cdd:PHA02592 221 ---TYELNGKTKLHITEIPVKYDRETYVAVLDPLEEKGK---IVSYDDCTED--GFRFKVTLKREENEEATHEKIMKDFG 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 335 LETNFSANMLSIV-DG-VPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILrgLVKAlDALDEVIAlirrspTV 412
Cdd:PHA02592 293 LIERVSQNITVINeNGkLKVYENAEDLIRDFVEIRKTYVQKRIQYEIKETEEAFDLA--LAKA-EFIKRVIA------GE 363
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1081184712 413 DDArQGLIKLLDVDEIQ--------ANEILAMQLRRLAALERQKIVDDLAEIE 457
Cdd:PHA02592 364 IVL-QGKTRSELTEELSdnkdfgeyADKLVAMNIYSMTSDEREKLQKEAEELE 415
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
19-394 |
5.92e-21 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 99.01 E-value: 5.92e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 19 INEEMqtsyIDYAMSVIVgRALPDVRDGMKPVHRRIIYAMYdhgyrpERSYVKSAKpVADTMG------NFHpHGDSAIY 92
Cdd:PLN03128 659 INKEL----ILFSQADLA-RSIPSMVDGLKPSQRKVLFACF------KRNLKSEIK-VAQLSGyvaehsAYH-HGEASLA 725
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 93 DTLVRMAQPWA------MRYPlvdgQGNFGSP---GNDGpAAMRYTECKMTPLAMEMVRDIREDAVEFSpNYDGKTREPD 163
Cdd:PLN03128 726 STIIGMAQDFVgsnninLLTP----SGQFGTRlqgGKDA-ASARYIFTRLSPITRALFPKDDDVLLNYL-NEDGQSIEPE 799
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 164 VLPSRVPNLLMNGSNGIAVGMATNIPPHNLNELAEAIYWMLdnyDADEQAALDAVMERVKGpdfptaglivgdqGIKDAY 243
Cdd:PLN03128 800 WYCPIIPMVLVNGSEGIGTGWSTFIPNYNPRDIIANIRRLL---RGEELEPMHPWYRGFKG-------------TITEVS 863
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 244 TTGRGSIRMRGVteIEEIGNRqVITITELPYQVNPDNFiHNIAEQVTAGKMVGISKIED--ESSDRVGMRIVVTLKRDAV 321
Cdd:PLN03128 864 TSRSGSYTVTGI--IEQIGDT-TIRITELPVRKWTQDY-KEFLEALLTGTKKKEPEIKDfkENHTDTTVHFTVTLSEEKM 939
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 322 PRVVLNNLYKHSQLETNFS-ANM---------------LSIVDG-VPrtLRLDqmlrYYVKhQIDVIVRRTKFRLDEAEK 384
Cdd:PLN03128 940 ARALAEGLEKKFKLSTTIStSNMhlfdkdgkikkydspEDILEEfFH--LRLD----LYVK-RKEVLLENLEYELKKLDN 1012
|
410
....*....|
gi 1081184712 385 RAHILRGLVK 394
Cdd:PLN03128 1013 KARFILAVVK 1022
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
38-470 |
3.35e-19 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 93.57 E-value: 3.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 38 RALPDVRDGMKPVHRRIIYAMYdhgyrpERSYVKSAKpVADTMG------NFHpHGDSAIYDTLVRMAQPW------AMR 105
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFACF------KRNLKNEIK-VAQLSGyvsehsAYH-HGEQSLQQTIVGMAQNFvgsnniNLL 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 106 YPlvDGQgnFGSP---GNDGPAAmRYTECKMTPLAmemvRDIREDAVEFSPNY---DGKTREPDVLPSRVPNLLMNGSNG 179
Cdd:PTZ00108 752 YP--CGQ--FGSRlqgGKDHAAA-RYIFTKLSKIT----RYIFPEEDDPILDYledDGQSVEPFYYVPIIPMVLVNGAEG 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 180 IAVGMATNIPPHNLNELaeaiywmldnydadeqaaLDAVMERVKGPDFPTaglivgdqgIKDAYTTGRGSIRMRGVTEIE 259
Cdd:PTZ00108 823 IGTGFSTSIPNYNPLDI------------------IDNLRRRLNGEEVRP---------LVPWYRGFKGTIERNPKGKFI 875
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 260 EIGN-----RQVITITELPYQVNPDNFIHNIAEQVTAGKMVgISKIEDESSDrVGMRIVVTLKRDAVPRVVLNNLYKHSQ 334
Cdd:PTZ00108 876 SKGIyekvpDGTVEITELPIGKWTEDYKEFLESETLKEKDV-IVDYRDYSTA-NTVHFTVKLNDGVLEQWEEEGIEKVFK 953
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 335 LETNFSANMLSIVD---GVPRTLRLDQMLRYYVKHQIDVIVRRTKFRLDEAEKRAHILRGLVKALDAL-DEVIALIRRSp 410
Cdd:PTZ00108 954 LKSTISTTNMVLFDengKIKKYSDALDILKEFYLVRLDLYKKRKEYLLGKLERELARLSNKVRFIKHViNGELVITNAK- 1032
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1081184712 411 tvddaRQGLIKLLD------VDEIQ--ANEILAMQLRRLAALERQKIVDDLAEIERKIADYKDILARP 470
Cdd:PTZ00108 1033 -----KKDLVKELKklgyvrFKDIIkkKSEKITAEEEEGAEEDDEADDEDDEEELGAAVSYDYLLSMP 1095
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
38-393 |
7.88e-11 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 66.04 E-value: 7.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 38 RALPDVRDGMKPVHRRIIYAMYdhgyrpERSYVKSAKpVADTMG------NFHpHGDSAIYDTLVRMAQPW--AMRYPLV 109
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFCSF------KRNFVKEAK-VAQLSGyvsehsAYH-HGEQSLASTIIGMAQDFvgSNNINLL 769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 110 DGQGNFG--SPGNDGPAAMRYTECKMTPLAMEMV-RDirEDAVEFSPNYDGKTREPDVLPSRVPNLLMNGSNGIAVGMAT 186
Cdd:PLN03237 770 LPNGQFGtrLQGGKDHASARYIFTRLSPITRFLFpKD--DDILLDYLNEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWST 847
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 187 NIPPHNLNELAEAIYWMLDnydadeqaalDAVMERVKgPDFPtaglivGDQGIKDAYTTGRGSIRMRgVTEIEEIGNRQV 266
Cdd:PLN03237 848 FIPNYNPRDIVANIRRLLN----------GESMEPMH-PWYR------GFKGTIEKTASKEGGCTYT-ITGLYEEVDETT 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081184712 267 ITITELPYQVNPDNFiHNIAEQVTAGK-MVGISKIED--ESSDRVGMRIVVTLKRDAVPRVVLNNLYKHSQLETNFSANM 343
Cdd:PLN03237 910 LRITELPIRRWTDDY-KEFLESLKTDNnKNKDPFIKDvkAYNDDTTVHFEVILSEENMLAAKQEGLLKKFKLTTTISTSN 988
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1081184712 344 LSIVD--GVPRT-------------LRLDqmlrYYVKHQiDVIVRRTKFRLDEAEKRAHILRGLV 393
Cdd:PLN03237 989 MHLFDskGVIKKydtpeqileeffhLRLE----YYEKRK-EVLLKNLEFELLKLENKVRFILAVV 1048
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
667-715 |
1.74e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 56.73 E-value: 1.74e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1081184712 667 DDLLLVSEQGQAIRFTADDdqLRPMGRATAGVKGMRFRGDDKLLAMTVV 715
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSE--IREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
515-560 |
2.67e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 56.34 E-value: 2.67e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1081184712 515 VVTITSTGYAKRTKVDAYKSQKRGGKGVRGAELKQDDVVKHFFICS 560
Cdd:pfam03989 3 LLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
563-612 |
1.42e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.33 E-value: 1.42e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1081184712 563 DWILFFTNFGRVYRLKAYELPEAGRTARGQHVANLLEfqpEERIAQVIQI 612
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKE---GDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
770-813 |
2.82e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 50.56 E-value: 2.82e-08
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1081184712 770 DQIFAITSAGGVIRTEVNQIRPSSRATMGVRLVDLADDVELLAI 813
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSV 44
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
719-767 |
6.06e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 49.41 E-value: 6.06e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1081184712 719 EFLLVATAGGYGKRTTIEEYNTQGRGGMGVMTFKyTPKRGKLIGALAVD 767
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN-LKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
620-662 |
3.72e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 44.40 E-value: 3.72e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1081184712 620 YLVLATRDGRVKKSRLTDYESAR--SAGLIAINLNEGDALIGAAL 662
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGrgAKGVKGINLKEGDKVVSVLV 46
|
|
| |
