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Conserved domains on  [gi|1084449165|gb|OGN15822|]
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MAG: hypothetical protein A3J47_02560 [Candidatus Yanofskybacteria bacterium RIFCSPHIGHO2_02_FULL_43_22]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Avd_IVP_like super family cl28927
proteins similar to the diversity-generating retroelement protein bAvd; A superfamily of ...
23-67 5.73e-09

proteins similar to the diversity-generating retroelement protein bAvd; A superfamily of four-helix bundles that form homopentamers, including the bacterial accessory variability determinant (bAvd) protein and a family of functionally uncharacterized bacterial proteins, some of which are encoded by an atypically large intervening sequence present within some 23S rRNA genes.


The actual alignment was detected with superfamily member cd16376:

Pssm-ID: 355803  Cd Length: 106  Bit Score: 48.30  E-value: 5.73e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1084449165  23 TNLEVLKVFVRLSSEIEIINVAIYIELESGLQEISKMTNGWIKYL 67
Cdd:cd16376    62 VKLELLKFLLRLAYELKLISNKKYEVLSEKLDEIGKMLGGWIKSL 106
 
Name Accession Description Interval E-value
Avd_like cd16376
diversity-generating retroelement protein bAvd and similar proteins; The bacterial accessory ...
23-67 5.73e-09

diversity-generating retroelement protein bAvd and similar proteins; The bacterial accessory variability determinant (bAvd) protein, together with a reverse transcriptase, is involved in retrohoming processes as part of a diversity-generating retroelement (DGR), a type of system that is involved in generating sequence variation in bacterial proteins by inserting coding information from a template region into a variable region of a protein coding gene. bAvd forms homopentamers and interacts with the reverse transcriptase as well as with DNA and/or RNA.


Pssm-ID: 319868  Cd Length: 106  Bit Score: 48.30  E-value: 5.73e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1084449165  23 TNLEVLKVFVRLSSEIEIINVAIYIELESGLQEISKMTNGWIKYL 67
Cdd:cd16376    62 VKLELLKFLLRLAYELKLISNKKYEVLSEKLDEIGKMLGGWIKSL 106
 
Name Accession Description Interval E-value
Avd_like cd16376
diversity-generating retroelement protein bAvd and similar proteins; The bacterial accessory ...
23-67 5.73e-09

diversity-generating retroelement protein bAvd and similar proteins; The bacterial accessory variability determinant (bAvd) protein, together with a reverse transcriptase, is involved in retrohoming processes as part of a diversity-generating retroelement (DGR), a type of system that is involved in generating sequence variation in bacterial proteins by inserting coding information from a template region into a variable region of a protein coding gene. bAvd forms homopentamers and interacts with the reverse transcriptase as well as with DNA and/or RNA.


Pssm-ID: 319868  Cd Length: 106  Bit Score: 48.30  E-value: 5.73e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1084449165  23 TNLEVLKVFVRLSSEIEIINVAIYIELESGLQEISKMTNGWIKYL 67
Cdd:cd16376    62 VKLELLKFLLRLAYELKLISNKKYEVLSEKLDEIGKMLGGWIKSL 106
23S_rRNA_IVP_like cd16377
23S rRNA-intervening sequence protein and similar proteins; A family of functionally ...
28-67 5.67e-03

23S rRNA-intervening sequence protein and similar proteins; A family of functionally uncharacterized bacterial proteins, some of which are encoded by an atypically large intervening sequence present within some 23S rRNA genes. The distantly related bAvd protein, which also forms a homopentamer of four-helix bundles, has been suggested to interact with nucleic acids and a reverse transcriptase.


Pssm-ID: 319869  Cd Length: 108  Bit Score: 32.75  E-value: 5.67e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1084449165  28 LKVFVRLSSEIEIINVAIYIELESGLQEISKMTNGWIKYL 67
Cdd:cd16377    69 LETQLILAKDLGYISEEEFEELLELLEEIGKMLNGLIKSL 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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