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Conserved domains on  [gi|1085032444|gb|OGS37660|]
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hypothetical protein A2293_17250 [Elusimicrobia bacterium RIFOXYB2_FULL_49_7]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SASA super family cl04187
Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this ...
 118-299 4.54e-11

Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665.


The actual alignment was detected with superfamily member pfam03629:

Pssm-ID: 427409  Cd Length: 227  Bit Score: 62.99  E-value: 4.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 118 GDAYLINGQSNAA----ANDYDDSVHYRCEWVRSTRRLNNVG-WGLAR---ADTIYADYTVGVwGLRLG---KLISDSNG 186
Cdd:pfam03629   2 KDIFLLAGQSNMAgrggVENWDGVVPPECQPPPRILRLNADLeWEEAReplHADIDAKKTCGV-GPGMAfanALLRAPPG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 187 IPVAIINGALGSTDIEDHLRYEpnptntyHLYGHLLTRAINAGIRDKVRALFWHQGENNSLDLS-YLNYAHNFDTLYHAW 265
Cdd:pfam03629  81 GVIGLVPCAVGGTSIEEWARGG-------LLYQEMVRRAKAALKGGEIKGILWYQGESDTSDEEdAAAYKEKLEKLITDL 153

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1085032444 266 KEDYpGLEKIYVFQGHPGCG-GSYQHQIREMQRKF 299
Cdd:pfam03629 154 RDDL-GLPDLPIIQVQLASGeGPYEEVVREAQLGI 187
Por_Secre_tail super family cl46851
Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 492-560 6.62e-07

Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber have on average twenty or more copies of this C-terminal domain, associated with sorting to the outer membrane and covalent modification. This domain targets proteins to type IX secretion systems and is secreted then cleaved off by a C-terminal signal peptidease. Based on similarity to other families it is likely that this domain adopts an immunoglobulin like fold.


The actual alignment was detected with superfamily member pfam18962:

Pssm-ID: 481191 [Multi-domain]  Cd Length: 75  Bit Score: 46.83  E-value: 6.62e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1085032444 492 VWPNPFNPMVRITVSGGWKTDEQrrkmaLKIYNVSGKLVMDLSAQPASLSSGIswNAAAFPSGIYIVRL 560
Cdd:pfam18962   1 IYPNPAKDVLNISLKNSNSSNLN-----ISIYDILGKLVKSNSKTNGNNTKTI--DVSNLSSGIYFVKI 62
 
Name Accession Description Interval E-value
SASA pfam03629
Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this ...
 118-299 4.54e-11

Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665.


Pssm-ID: 427409  Cd Length: 227  Bit Score: 62.99  E-value: 4.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 118 GDAYLINGQSNAA----ANDYDDSVHYRCEWVRSTRRLNNVG-WGLAR---ADTIYADYTVGVwGLRLG---KLISDSNG 186
Cdd:pfam03629   2 KDIFLLAGQSNMAgrggVENWDGVVPPECQPPPRILRLNADLeWEEAReplHADIDAKKTCGV-GPGMAfanALLRAPPG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 187 IPVAIINGALGSTDIEDHLRYEpnptntyHLYGHLLTRAINAGIRDKVRALFWHQGENNSLDLS-YLNYAHNFDTLYHAW 265
Cdd:pfam03629  81 GVIGLVPCAVGGTSIEEWARGG-------LLYQEMVRRAKAALKGGEIKGILWYQGESDTSDEEdAAAYKEKLEKLITDL 153

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1085032444 266 KEDYpGLEKIYVFQGHPGCG-GSYQHQIREMQRKF 299
Cdd:pfam03629 154 RDDL-GLPDLPIIQVQLASGeGPYEEVVREAQLGI 187
Por_Secre_tail pfam18962
Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 492-560 6.62e-07

Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber have on average twenty or more copies of this C-terminal domain, associated with sorting to the outer membrane and covalent modification. This domain targets proteins to type IX secretion systems and is secreted then cleaved off by a C-terminal signal peptidease. Based on similarity to other families it is likely that this domain adopts an immunoglobulin like fold.


Pssm-ID: 436869 [Multi-domain]  Cd Length: 75  Bit Score: 46.83  E-value: 6.62e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1085032444 492 VWPNPFNPMVRITVSGGWKTDEQrrkmaLKIYNVSGKLVMDLSAQPASLSSGIswNAAAFPSGIYIVRL 560
Cdd:pfam18962   1 IYPNPAKDVLNISLKNSNSSNLN-----ISIYDILGKLVKSNSKTNGNNTKTI--DVSNLSSGIYFVKI 62
Por_Secre_tail TIGR04183
Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 492-572 3.27e-04

Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber average twenty or more copies of a C-terminal domain, represented by this model, associated with sorting to the outer membrane and covalent modification.


Pssm-ID: 275036 [Multi-domain]  Cd Length: 72  Bit Score: 39.31  E-value: 3.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 492 VWPNPFNPMVRITVSGGWKTDEqrrkmaLKIYNVSGKLVMDlsaqpASLSSGISWNAAAFPSGIYIVRLIREDDILERTI 571
Cdd:TIGR04183   1 IYPNPAKGTLIIILLSSSGKVK------VEIYDLSGKLVKK-----TTLNNSNSIDLSNLSSGVYIVKITTGNGTITKKI 69


                  .
gi 1085032444 572 M 572
Cdd:TIGR04183  70 I 70
T9SSA_dep_M36 NF038113
T9SS-dependent M36 family metallopeptidase; Members of this family have an M36 family ...
 457-559 1.89e-03

T9SS-dependent M36 family metallopeptidase; Members of this family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal T9SS type A sorting domain (see TIGR04131).


Pssm-ID: 468356 [Multi-domain]  Cd Length: 868  Bit Score: 41.18  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 457 RGVGALTF-------------FEFPLDSEQVTTIGsiqTDRTQNSKIQVWPNPFNPMVRITVsggwkTDEQRRKMALKIY 523
Cdd:NF038113  749 RGLGVSASqgssnsrsdqvedFTVPPPLANCTSLA---TNEFGANKFIIYPNPAKGEIFISF-----SNKDSGEVKVKVY 820

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1085032444 524 NVSGKLVmdLSAQpASLSSGISWNAAAFPSGIYIVR 559
Cdd:NF038113  821 DINGRLV--LSDK-VELTNTKTINTSGLQSGIYIVK 853
 
Name Accession Description Interval E-value
SASA pfam03629
Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this ...
 118-299 4.54e-11

Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665.


Pssm-ID: 427409  Cd Length: 227  Bit Score: 62.99  E-value: 4.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 118 GDAYLINGQSNAA----ANDYDDSVHYRCEWVRSTRRLNNVG-WGLAR---ADTIYADYTVGVwGLRLG---KLISDSNG 186
Cdd:pfam03629   2 KDIFLLAGQSNMAgrggVENWDGVVPPECQPPPRILRLNADLeWEEAReplHADIDAKKTCGV-GPGMAfanALLRAPPG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 187 IPVAIINGALGSTDIEDHLRYEpnptntyHLYGHLLTRAINAGIRDKVRALFWHQGENNSLDLS-YLNYAHNFDTLYHAW 265
Cdd:pfam03629  81 GVIGLVPCAVGGTSIEEWARGG-------LLYQEMVRRAKAALKGGEIKGILWYQGESDTSDEEdAAAYKEKLEKLITDL 153

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1085032444 266 KEDYpGLEKIYVFQGHPGCG-GSYQHQIREMQRKF 299
Cdd:pfam03629 154 RDDL-GLPDLPIIQVQLASGeGPYEEVVREAQLGI 187
Por_Secre_tail pfam18962
Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 492-560 6.62e-07

Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber have on average twenty or more copies of this C-terminal domain, associated with sorting to the outer membrane and covalent modification. This domain targets proteins to type IX secretion systems and is secreted then cleaved off by a C-terminal signal peptidease. Based on similarity to other families it is likely that this domain adopts an immunoglobulin like fold.


Pssm-ID: 436869 [Multi-domain]  Cd Length: 75  Bit Score: 46.83  E-value: 6.62e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1085032444 492 VWPNPFNPMVRITVSGGWKTDEQrrkmaLKIYNVSGKLVMDLSAQPASLSSGIswNAAAFPSGIYIVRL 560
Cdd:pfam18962   1 IYPNPAKDVLNISLKNSNSSNLN-----ISIYDILGKLVKSNSKTNGNNTKTI--DVSNLSSGIYFVKI 62
Por_Secre_tail TIGR04183
Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 492-572 3.27e-04

Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber average twenty or more copies of a C-terminal domain, represented by this model, associated with sorting to the outer membrane and covalent modification.


Pssm-ID: 275036 [Multi-domain]  Cd Length: 72  Bit Score: 39.31  E-value: 3.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 492 VWPNPFNPMVRITVSGGWKTDEqrrkmaLKIYNVSGKLVMDlsaqpASLSSGISWNAAAFPSGIYIVRLIREDDILERTI 571
Cdd:TIGR04183   1 IYPNPAKGTLIIILLSSSGKVK------VEIYDLSGKLVKK-----TTLNNSNSIDLSNLSSGVYIVKITTGNGTITKKI 69


                  .
gi 1085032444 572 M 572
Cdd:TIGR04183  70 I 70
T9SSA_dep_M36 NF038113
T9SS-dependent M36 family metallopeptidase; Members of this family have an M36 family ...
 457-559 1.89e-03

T9SS-dependent M36 family metallopeptidase; Members of this family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal T9SS type A sorting domain (see TIGR04131).


Pssm-ID: 468356 [Multi-domain]  Cd Length: 868  Bit Score: 41.18  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1085032444 457 RGVGALTF-------------FEFPLDSEQVTTIGsiqTDRTQNSKIQVWPNPFNPMVRITVsggwkTDEQRRKMALKIY 523
Cdd:NF038113  749 RGLGVSASqgssnsrsdqvedFTVPPPLANCTSLA---TNEFGANKFIIYPNPAKGEIFISF-----SNKDSGEVKVKVY 820

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1085032444 524 NVSGKLVmdLSAQpASLSSGISWNAAAFPSGIYIVR 559
Cdd:NF038113  821 DINGRLV--LSDK-VELTNTKTINTSGLQSGIYIVK 853
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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