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Conserved domains on  [gi|1087994491|gb|OGY67619|]
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MAG: hypothetical protein A3I89_01240 [Candidatus Harrisonbacteria bacterium RIFCSPLOWO2_02_FULL_41_11]

Protein Classification

glycosyltransferase family 4 protein( domain architecture ID 10133453)

glycosyltransferase family 4 (GT4) protein catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds

CAZY:  GT4
EC:  2.4.-.-
Gene Ontology:  GO:0016757|GO:0006486
PubMed:  12691742|10521532|16037492
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 15-289 4.44e-38

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


:

Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 138.05  E-value: 4.44e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  15 KIYLFFREYDILYSRELLTGLFFRNYFFE--------LHNFLqkPGRFYKFLIFKPRTI-------------FALTGFLK 73
Cdd:cd03801    75 RPLLRLRKFDVVHAHGLLAALLAALLALLlgaplvvtLHGAE--PGRLLLLLAAERRLLaraeallrradavIAVSEALR 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  74 DNLKKT-GIADKKIMILPDAVDLAEFSPsldreGARKKLNLPLDKKIIIYTGSFlfYKWKGIGSLLDAGKLLKD---DFL 149
Cdd:cd03801   153 DELRALgGIPPEKIVVIPNGVDLERFSP-----PLRRKLGIPPDRPVLLFVGRL--SPRKGVDLLLEALAKLLRrgpDVR 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 150 FVLVGGHPWEIRKLKERPIPL--NVLLVSYQKHEIIPYYLKAADIFVIPnekgdaiSEKYTSPLKLFEYMASRRPIISSD 227
Cdd:cd03801   226 LVIVGGDGPLRAELEELELGLgdRVRFLGFVPDEELPALYAAADVFVLP-------SRYEGFGLVVLEAMAAGLPVVATD 298

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1087994491 228 LPSLREILTEKEA-LFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKD-YTWEKRAKKII 289
Cdd:cd03801   299 VGGLPEVVEDGEGgLVVPPDDVEALADALLRLLADPELRARLGRAARERVAErFSWERVAERLL 362
 
Name Accession Description Interval E-value
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 15-289 4.44e-38

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 138.05  E-value: 4.44e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  15 KIYLFFREYDILYSRELLTGLFFRNYFFE--------LHNFLqkPGRFYKFLIFKPRTI-------------FALTGFLK 73
Cdd:cd03801    75 RPLLRLRKFDVVHAHGLLAALLAALLALLlgaplvvtLHGAE--PGRLLLLLAAERRLLaraeallrradavIAVSEALR 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  74 DNLKKT-GIADKKIMILPDAVDLAEFSPsldreGARKKLNLPLDKKIIIYTGSFlfYKWKGIGSLLDAGKLLKD---DFL 149
Cdd:cd03801   153 DELRALgGIPPEKIVVIPNGVDLERFSP-----PLRRKLGIPPDRPVLLFVGRL--SPRKGVDLLLEALAKLLRrgpDVR 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 150 FVLVGGHPWEIRKLKERPIPL--NVLLVSYQKHEIIPYYLKAADIFVIPnekgdaiSEKYTSPLKLFEYMASRRPIISSD 227
Cdd:cd03801   226 LVIVGGDGPLRAELEELELGLgdRVRFLGFVPDEELPALYAAADVFVLP-------SRYEGFGLVVLEAMAAGLPVVATD 298

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1087994491 228 LPSLREILTEKEA-LFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKD-YTWEKRAKKII 289
Cdd:cd03801   299 VGGLPEVVEDGEGgLVVPPDDVEALADALLRLLADPELRARLGRAARERVAErFSWERVAERLL 362
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
117-261 1.60e-23

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 93.34  E-value: 1.60e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 117 KKIIIYTGSfLFYKWKGIGSLLDAGKLLK---DDFLFVLVGGHPWEIRKLKERPIPLNVLLVSYQKHeiIPYYLKAADIF 193
Cdd:pfam13692   1 RPVILFVGR-LHPNVKGVDYLLEAVPLLRkrdNDVRLVIVGDGPEEELEELAAGLEDRVIFTGFVED--LAELLAAADVF 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1087994491 194 VIPnekgdaiSEKYTSPLKLFEYMASRRPIISSDLPSLREILTEKEALFFEAGNPADLVRAIKKIFED 261
Cdd:pfam13692  78 VLP-------SLYEGFGLKLLEAMAAGLPVVATDVGGIPELVDGENGLLVPPGDPEALAEAILRLLED 138
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 180-289 4.56e-23

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 91.59  E-value: 4.56e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 180 HEIIPYYLKAADIFVIPnekgdaiSEKYTSPLKLFEYMASRRPIISSDLPSLREILTEKEA-LFFEAGNPADLVRAIKKI 258
Cdd:COG0438    11 DLLLEALLAAADVFVLP-------SRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETgLLVPPGDPEALAEAILRL 83

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1087994491 259 FEDKDLSEKLSYNAYQKV-KDYTWEKRAKKII 289
Cdd:COG0438    84 LEDPELRRRLGEAARERAeERFSWEAIAERLL 115
PRK10307 PRK10307
colanic acid biosynthesis glycosyltransferase WcaI;
74-268 2.12e-14

colanic acid biosynthesis glycosyltransferase WcaI;


Pssm-ID: 236670 [Multi-domain]  Cd Length: 412  Bit Score: 72.70  E-value: 2.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  74 DNLKKTGIADKKIMILPDAVDLAEFSPsLDREGA---RKKLNLPLDKKIIIYTGSfLFYKwKGIGSLLDAGKLL--KDDF 148
Cdd:PRK10307  184 NKAREKGVAAEKVIFFPNWSEVARFQP-VADADVdalRAQLGLPDGKKIVLYSGN-IGEK-QGLELVIDAARRLrdRPDL 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 149 LFVLVGGHPWEIRKLK---ERPIPlNVLLVSYQKHEIIPYYLKAADIFVIPNEKG--DAIsekytSPLKLFEYMASRRPI 223
Cdd:PRK10307  261 IFVICGQGGGKARLEKmaqCRGLP-NVHFLPLQPYDRLPALLKMADCHLLPQKAGaaDLV-----LPSKLTNMLASGRNV 334

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1087994491 224 ISSDLP--SLREiLTEKEALFFEAGNPADLVRAIKKIFEDKDLSEKL 268
Cdd:PRK10307  335 VATAEPgtELGQ-LVEGIGVCVEPESVEALVAAIAALARQALLRPKL 380
 
Name Accession Description Interval E-value
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 15-289 4.44e-38

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 138.05  E-value: 4.44e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  15 KIYLFFREYDILYSRELLTGLFFRNYFFE--------LHNFLqkPGRFYKFLIFKPRTI-------------FALTGFLK 73
Cdd:cd03801    75 RPLLRLRKFDVVHAHGLLAALLAALLALLlgaplvvtLHGAE--PGRLLLLLAAERRLLaraeallrradavIAVSEALR 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  74 DNLKKT-GIADKKIMILPDAVDLAEFSPsldreGARKKLNLPLDKKIIIYTGSFlfYKWKGIGSLLDAGKLLKD---DFL 149
Cdd:cd03801   153 DELRALgGIPPEKIVVIPNGVDLERFSP-----PLRRKLGIPPDRPVLLFVGRL--SPRKGVDLLLEALAKLLRrgpDVR 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 150 FVLVGGHPWEIRKLKERPIPL--NVLLVSYQKHEIIPYYLKAADIFVIPnekgdaiSEKYTSPLKLFEYMASRRPIISSD 227
Cdd:cd03801   226 LVIVGGDGPLRAELEELELGLgdRVRFLGFVPDEELPALYAAADVFVLP-------SRYEGFGLVVLEAMAAGLPVVATD 298

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1087994491 228 LPSLREILTEKEA-LFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKD-YTWEKRAKKII 289
Cdd:cd03801   299 VGGLPEVVEDGEGgLVVPPDDVEALADALLRLLADPELRARLGRAARERVAErFSWERVAERLL 362
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 25-289 2.41e-37

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 136.70  E-value: 2.41e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  25 ILYSRELLTGLFFRNYFFELHNFLQKPGRFYKFLIFKPRTIFALTGFLKDNLKKTGIADKKIMILPDAVDLAEFSPsLDR 104
Cdd:cd03794   127 ILDVRDLWPESLIALGVLKKGSLLKLLKKLERKLYRLADAIIVLSPGLKEYLLRKGVPKEKIIVIPNWADLEEFKP-PPK 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 105 EGARKKLNLPlDKKIIIYTGSFlfYKWKGIGSLLDAGKLLK--DDFLFVLVGG---HPWEIRKLKERPIPlNVLLVSYQK 179
Cdd:cd03794   206 DELRKKLGLD-DKFVVVYAGNI--GKAQGLETLLEAAERLKrrPDIRFLFVGDgdeKERLKELAKARGLD-NVTFLGRVP 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 180 HEIIPYYLKAADIFVIPNEKGDAisEKYTSPLKLFEYMASRRPIISSDLPSLREILTEKEA-LFFEAGNPADLVRAIKKI 258
Cdd:cd03794   282 KEEVPELLSAADVGLVPLKDNPA--NRGSSPSKLFEYMAAGKPILASDDGGSDLAVEINGCgLVVEPGDPEALADAILEL 359

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1087994491 259 FEDKDLSEKLSYNAYQKVK-DYTWEKRAKKII 289
Cdd:cd03794   360 LDDPELRRAMGENGRELAEeKFSREKLADRLL 391
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
117-261 1.60e-23

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 93.34  E-value: 1.60e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 117 KKIIIYTGSfLFYKWKGIGSLLDAGKLLK---DDFLFVLVGGHPWEIRKLKERPIPLNVLLVSYQKHeiIPYYLKAADIF 193
Cdd:pfam13692   1 RPVILFVGR-LHPNVKGVDYLLEAVPLLRkrdNDVRLVIVGDGPEEELEELAAGLEDRVIFTGFVED--LAELLAAADVF 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1087994491 194 VIPnekgdaiSEKYTSPLKLFEYMASRRPIISSDLPSLREILTEKEALFFEAGNPADLVRAIKKIFED 261
Cdd:pfam13692  78 VLP-------SLYEGFGLKLLEAMAAGLPVVATDVGGIPELVDGENGLLVPPGDPEALAEAILRLLED 138
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 180-289 4.56e-23

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 91.59  E-value: 4.56e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 180 HEIIPYYLKAADIFVIPnekgdaiSEKYTSPLKLFEYMASRRPIISSDLPSLREILTEKEA-LFFEAGNPADLVRAIKKI 258
Cdd:COG0438    11 DLLLEALLAAADVFVLP-------SRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETgLLVPPGDPEALAEAILRL 83

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1087994491 259 FEDKDLSEKLSYNAYQKV-KDYTWEKRAKKII 289
Cdd:COG0438    84 LEDPELRRRLGEAARERAeERFSWEAIAERLL 115
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 116-275 5.66e-23

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 92.34  E-value: 5.66e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 116 DKKIIIYTGSFLfyKWKGIGSLLDAGKLLK---DDFLFVLVGGHPWE---IRKLKERPIPLNVLLVSYQKHEIIPYYLKA 189
Cdd:pfam00534   1 KKKIILFVGRLE--PEKGLDLLIKAFALLKeknPNLKLVIAGDGEEEkrlKKLAEKLGLGDNVIFLGFVSDEDLPELLKI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 190 ADIFVIPnekgdAISEKYtsPLKLFEYMASRRPIISSDLPSLREILTE-KEALFFEAGNPADLVRAIKKIFEDKDLSEKL 268
Cdd:pfam00534  79 ADVFVLP-----SRYEGF--GIVLLEAMACGLPVIASDVGGPPEVVKDgETGFLVKPNNAEALAEAIDKLLEDEELRERL 151


                  ....*..
gi 1087994491 269 SYNAYQK 275
Cdd:pfam00534 152 GENARKR 158
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 73-279 5.54e-22

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 94.31  E-value: 5.54e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  73 KDNLKKTGIADKKIMILPDAVDLAEFSPSL-DREGARKKLNLPLDKKIIIYTGSFlfYKWKGIGSLLDAGKLLKD---DF 148
Cdd:cd03807   145 AEFHQEQGYAKNKIVVIYNGIDLFKLSPDDaSRARARRRLGLAEDRRVIGIVGRL--HPVKDHSDLLRAAALLVEthpDL 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 149 LFVLVGGHPWEI---RKLKERPIPLNVLLVSYQKHeiIPYYLKAADIFVIPnekgdaiSEKYTSPLKLFEYMASRRPIIS 225
Cdd:cd03807   223 RLLLVGRGPERPnleRLLLELGLEDRVHLLGERSD--VPALLPAMDIFVLS-------SRTEGFPNALLEAMACGLPVVA 293

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1087994491 226 SDLPSLREILTEKEALFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKDY 279
Cdd:cd03807   294 TDVGGAAELVDDGTGFLVPAGDPQALADAIRALLEDPEKRARLGRAARERIANE 347
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 36-289 6.95e-22

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 93.97  E-value: 6.95e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  36 FFRNYFFELHNFLqkpgrfYKFLIFKPRTIFALTGFLKDNLKKT-GIADKKIMILPDAVDLAEFSPSLDREGARKKLnlp 114
Cdd:cd03809   119 FFPKRFRLYYRLL------LPISLRRADAIITVSEATRDDIIKFyGVPPEKIVVIPLGVDPSFFPPESAAVLIAKYL--- 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 115 LDKKIIIYTGSFlfYKWKGIGSLLDAGKLLKDDFL---FVLVGGHPWEIRKL----KERPIPLNVLLVSYQKHEIIPYYL 187
Cdd:cd03809   190 LPEPYFLYVGTL--EPRKNHERLLKAFALLKKQGGdlkLVIVGGKGWEDEELldlvKKLGLGGRVRFLGYVSDEDLPALY 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 188 KAADIFVIPnekgdAISEkyTSPLKLFEYMASRRPIISSDLPSLREIlTEKEALFFEAGNPADLVRAIKKIFEDKDLSEK 267
Cdd:cd03809   268 RGARAFVFP-----SLYE--GFGLPVLEAMACGTPVIASNISVLPEV-AGDAALYFDPLDPESIADAILRLLEDPSLREE 339

                         250       260
                  ....*....|....*....|..
gi 1087994491 268 LSYNAYQKVKDYTWEKRAKKII 289
Cdd:cd03809   340 LIRKGLERAKKFSWEKTAEKTL 361
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 44-274 5.95e-21

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 91.26  E-value: 5.95e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  44 LHNFLQKPGRFYKFLIFKPRTIFALTGFLKDNLKKTGIADK-KIMILPDAVDLAEFSPSLDREgARKKLNLPLDKKIIIY 122
Cdd:cd03819   109 SYLATYHPKDFALAVRARGDRVIAVSELVRDHLIEALGVDPeRIRVIPNGVDTDRFPPEAEAE-ERAQLGLPEGKPVVGY 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 123 TGsfLFYKWKGIGSLLDAGKLLKD--DFLFVLVGGHP--WEIRKLKERP-IPLNVLLVSYqkHEIIPYYLKAADIFVIPn 197
Cdd:cd03819   188 VG--RLSPEKGWLLLVDAAAELKDepDFRLLVAGDGPerDEIRRLVERLgLRDRVTFTGF--REDVPAALAASDVVVLP- 262

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1087994491 198 ekgdaiSEKYTSPLKLFEYMASRRPIISSDLPSLREILT-EKEALFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQ 274
Cdd:cd03819   263 ------SLHEEFGRVALEAMACGTPVVATDVGGAREIVVhGRTGLLVPPGDAEALADAIRAAKLLPEAREKLQAAAAL 334
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 45-289 1.20e-20

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 90.47  E-value: 1.20e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  45 HNFLQKpgrfYKFLIFKPRTIFALTGFLKDNLKKTGI-ADKKIMILPDAVDLAEFSPsLDREGARKKLNLPLDKKIIIYT 123
Cdd:cd03825   125 QLFRRK----REALAKKRLTIVAPSRWLADMVRRSPLlKGLPVVVIPNGIDTEIFAP-VDKAKARKRLGIPQDKKVILFG 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 124 GSFLFYKWKGIGSLLDAGKLL--KDDFLFVLVGGHPWEIRKLKERPIPLNVLLVSYQKHEIipyyLKAADIFVIPnekgd 201
Cdd:cd03825   200 AESVTKPRKGFDELIEALKLLatKDDLLLVVFGKNDPQIVILPFDIISLGYIDDDEQLVDI----YSAADLFVHP----- 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 202 aiSEKYTSPLKLFEYMASRRPIISSDLPSLREILTEKEALFF-EAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKV-KDY 279
Cdd:cd03825   271 --SLADNLPNTLLEAMACGTPVVAFDTGGSPEIVQHGVTGYLvPPGDVQALAEAIEWLLANPKERESLGERARALAeNHF 348

                         250
                  ....*....|
gi 1087994491 280 TWEKRAKKII 289
Cdd:cd03825   349 DQRVQAQRYL 358
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 45-289 4.33e-20

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 88.98  E-value: 4.33e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  45 HNFLQKPG--RFYKFLIFKPRTIFALTGFLKDNLKKTGIADKKIMILPDAVDLAEFSPSLDREGarkklnLPLDKKIIIY 122
Cdd:cd03798   132 NVFPPRSLlrKLLRWALRRAARVIAVSKALAEELVALGVPRDRVDVIPNGVDPARFQPEDRGLG------LPLDAFVILF 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 123 TGSflFYKWKGIGSLLDAGKLLKD---DFLFVLVGGHP------WEIRKLKERPiplNVLLVSYQKHEIIPYYLKAADIF 193
Cdd:cd03798   206 VGR--LIPRKGIDLLLEAFARLAKarpDVVLLIVGDGPlrealrALAEDLGLGD---RVTFTGRLPHEQVPAYYRACDVF 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 194 VIPnekgdaiSEKYTSPLKLFEYMASRRPIISSDLPSLREILTEKEALFFEA-GNPADLVRAIKKIFEDKDLSEKLSYNA 272
Cdd:cd03798   281 VLP-------SRHEGFGLVLLEAMACGLPVVATDVGGIPEVVGDPETGLLVPpGDADALAAALRRALAEPYLRELGEAAR 353

                         250
                  ....*....|....*..
gi 1087994491 273 YQKVKDYTWEKRAKKII 289
Cdd:cd03798   354 ARVAERFSWVKAADRIA 370
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 53-288 7.45e-20

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 88.49  E-value: 7.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  53 RFYKFLIFKPRTIFALTGFLKDNLKKTGIaDKKIMILPDAVDLAEFSPSLDREgARKKLNLPLDKKIIIYTGSFLfyKWK 132
Cdd:cd03817   139 KLVRRFYNHTDAVIAPSEKIKDTLREYGV-KGPIEVIPNGIDLDKFEKPLNTE-ERRKLGLPPDEPILLYVGRLA--KEK 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 133 GIGSLLDAGKLLKD--DFLFVLVGGHPwEIRKLKERPIPLN----VLLVSYQKHEIIPYYLKAADIFVIPnekgdAISEk 206
Cdd:cd03817   215 NIDFLLRAFAELKKepNIKLVIVGDGP-EREELKELARELGladkVIFTGFVPREELPEYYKAADLFVFA-----STTE- 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 207 yTSPLKLFEYMASRRPIISSDLPSLREILTEKEALFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKDYTWEKRAK 286
Cdd:cd03817   288 -TQGLVYLEAMAAGLPVVAAKDPAASELVEDGENGFLFEPNDETLAEKLLHLRENLELLRKLSKNAEISAREFAFAKSVE 366


                  ..
gi 1087994491 287 KI 288
Cdd:cd03817   367 KL 368
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 80-285 5.36e-19

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 86.14  E-value: 5.36e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  80 GIADKKIMILPDAVDLAEFSPSLDREGARKKLNLPLDKKIIIYTGSFLfyKWKGIGSLLDA-GKLLKDDFL--FVLVGGH 156
Cdd:cd03800   183 GADPSRINVVPPGVDLERFFPVDRAEARRARLLLPPDKPVVLALGRLD--PRKGIDTLVRAfAQLPELRELanLVLVGGP 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 157 PWEIRKLKERPIP--LNVLLVS-------YQKHEIIPYYLKAADIFVIPNekgdaisekYTSP--LKLFEYMASRRPIIS 225
Cdd:cd03800   261 SDDPLSMDREELAelAEELGLIdrvrfpgRVSRDDLPELYRAADVFVVPS---------LYEPfgLTAIEAMACGTPVVA 331

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1087994491 226 SDLPSLREILTEKE-ALFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKD-YTWEKRA 285
Cdd:cd03800   332 TAVGGLQDIVRDGRtGLLVDPHDPEALAAALRRLLDDPALWQRLSRAGLERARAhYTWESVA 393
GT4_mannosyltransferase-like cd03822
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ...
 77-287 5.15e-18

mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.


Pssm-ID: 340849 [Multi-domain]  Cd Length: 370  Bit Score: 83.20  E-value: 5.15e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  77 KKTGIADKKIMILPDAVdlaeFSPSLDREGARKKLNLPLDKKIIIYTGsfLFYKWKGIGSLLDAGKLLKDDF---LFVLV 153
Cdd:cd03822   151 RIKLIPAVNIEVIPHGV----PEVPQDPTTALKRLLLPEGKKVILTFG--FIGPGKGLEILLEALPELKAEFpdvRLVIA 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 154 GG-HP----WEIRKLKERPIPLNVLLVSYQKH------EIIPYYLKAADIFVIPnekgdAISEKYTSPLKLFEYMASRRP 222
Cdd:cd03822   225 GElHPslarYEGERYRKAAIEELGLQDHVDFHnnflpeEEVPRYISAADVVVLP-----YLNTEQSSSGTLSYAIACGKP 299

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1087994491 223 IISSDLPSLREILTEKEALFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKDYTWEKRAKK 287
Cdd:cd03822   300 VISTPLRHAEELLADGRGVLVPFDDPSAIAEAILRLLEDDERRQAIAERAYAYARAMTWESIADR 364
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 63-283 7.13e-18

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 82.73  E-value: 7.13e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  63 RTIFALTGFLKDNLKKTGIADkkIMILPDAVDLAEFSPSLDREGARKKLnLPLDKKIIIYTGSFLFYKwkGIGSLLDAGK 142
Cdd:cd03814   147 DTTLVPSPSIARELEGHGFER--VRLWPRGVDTELFHPSRRDAALRRRL-GPPGRPLLLYVGRLAPEK--NLEALLDADL 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 143 LLKD--DFLFVLVGGHPwEIRKLKERPipLNVLLVSYQKHEIIPYYLKAADIFVIPNEkgdaiSEkyTSPLKLFEYMASR 220
Cdd:cd03814   222 PLAAspPVRLVVVGDGP-ARAELEARG--PDVIFTGFLTGEELARAYASADVFVFPSR-----TE--TFGLVVLEAMASG 291

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1087994491 221 RPIISSDLPSLREILTEKEA-LFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKDYTWEK 283
Cdd:cd03814   292 LPVVAADAGGPRDIVRPGGTgALVEPGDAAAFAAALRALLEDPELRRRMAARARAEAERYSWEA 355
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 55-288 1.22e-16

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 79.18  E-value: 1.22e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  55 YKFLIFKPRTIFALTGFLKDNLKKTGIADKK--IMILPDAVDLAEFSPSLDregarkklNLPLDKKIIIYTGSFLfyKWK 132
Cdd:cd03808   133 EKLALLFTDKVIFVNEDDRDLAIKKGIIKKKktVLIPGSGVDLDRFQYSPE--------SLPSEKVVFLFVARLL--KDK 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 133 GIGSLLDAGKLLKD---DFLFVLVGGHPWE---IRKLKERPIPLNVLLVSYQKHeiIPYYLKAADIFVIPnekgdaisek 206
Cdd:cd03808   203 GIDELIEAAKILKKkgpNVRFLLVGDGELEnpsEILIEKLGLEGRIEFLGFRSD--VPELLAESDVFVLP---------- 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 207 ytS-----PLKLFEYMASRRPIISSDLPSLREILTEKEALF-FEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKV-KDY 279
Cdd:cd03808   271 --SyreglPRSLLEAMAAGRPVITTDVPGCRELVIDGVNGFlVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVeEKF 348


                  ....*....
gi 1087994491 280 TWEKRAKKI 288
Cdd:cd03808   349 DEEKVVNKL 357
PRK10307 PRK10307
colanic acid biosynthesis glycosyltransferase WcaI;
74-268 2.12e-14

colanic acid biosynthesis glycosyltransferase WcaI;


Pssm-ID: 236670 [Multi-domain]  Cd Length: 412  Bit Score: 72.70  E-value: 2.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  74 DNLKKTGIADKKIMILPDAVDLAEFSPsLDREGA---RKKLNLPLDKKIIIYTGSfLFYKwKGIGSLLDAGKLL--KDDF 148
Cdd:PRK10307  184 NKAREKGVAAEKVIFFPNWSEVARFQP-VADADVdalRAQLGLPDGKKIVLYSGN-IGEK-QGLELVIDAARRLrdRPDL 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 149 LFVLVGGHPWEIRKLK---ERPIPlNVLLVSYQKHEIIPYYLKAADIFVIPNEKG--DAIsekytSPLKLFEYMASRRPI 223
Cdd:PRK10307  261 IFVICGQGGGKARLEKmaqCRGLP-NVHFLPLQPYDRLPALLKMADCHLLPQKAGaaDLV-----LPSKLTNMLASGRNV 334

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1087994491 224 ISSDLP--SLREiLTEKEALFFEAGNPADLVRAIKKIFEDKDLSEKL 268
Cdd:PRK10307  335 VATAEPgtELGQ-LVEGIGVCVEPESVEALVAAIAALARQALLRPKL 380
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 37-277 3.94e-13

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 68.89  E-value: 3.94e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  37 FRNYFFELHN-FLQKPGRfykflifkpRTIFALTGFLKDNLKKTGIADKKIMILPDAVdlaefSPSLDREGARKklnlPL 115
Cdd:cd03823   127 LHDYWLLCPRqFLFKKGG---------DAVLAPSRFTANLHEANGLFSARISVIPNAV-----EPDLAPPPRRR----PG 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 116 DKKI-IIYTGSFLFykWKGIGSLLDAGKLLKD-DFLFVLVGG---HPWEIRKLKERpiplnVLLVSYQKHEIIPYYLKAA 190
Cdd:cd03823   189 TERLrFGYIGRLTE--EKGIDLLVEAFKRLPReDIELVIAGHgplSDERQIEGGRR-----IAFLGRVPTDDIKDFYEKI 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 191 DIFVIP---NEkgdaisekyTSPLKLFEYMASRRPIISSDLPSLRE-ILTEKEALFFEAGNPADLVRAIKKIFEDKDLSE 266
Cdd:cd03823   262 DVLVVPsiwPE---------PFGLVVREAIAAGLPVIASDLGGIAElIQPGVNGLLFAPGDAEDLAAAMRRLLTDPALLE 332

                         250
                  ....*....|.
gi 1087994491 267 KLSYNAYQKVK 277
Cdd:cd03823   333 RLRAGAEPPRS 343
GT4_TuaH-like cd04950
teichuronic acid biosynthesis glycosyltransferase TuaH and similar proteins; Members of this ...
 85-288 2.56e-12

teichuronic acid biosynthesis glycosyltransferase TuaH and similar proteins; Members of this family may function in teichuronic acid biosynthesis/cell wall biogenesis. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340856 [Multi-domain]  Cd Length: 373  Bit Score: 66.62  E-value: 2.56e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  85 KIMILPDAVDLAEFSPsldregARKKLNLPLDKKIIiyTGSFLFYkwkgIG--------SLLDAGKLLKDDFLFVLVGGH 156
Cdd:cd04950   174 NVHPIPNGVDVEHFAA------ARQPLDDPIDLREI--PGPVLGF----FGaidekldfDLIEELAKARPQWNFVFIGPV 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 157 PWEIRK-LKERPiplNVLLVSYQKHEIIPYYLKAADIFVIPNEKGDaiSEKYTSPLKLFEYMASRRPIISSDLPSLreIL 235
Cdd:cd04950   242 VKIDPSsLPRAP---NIHWLGPKPYKELPAYLAGFDVALLPFALNE--YTRFISPLKLFEYLAAGKPVVATSIPSV--VR 314

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1087994491 236 TEKEAlFFEAGNPADLVRAIKKIFEDKDlSEKLSYNAYQKVKDYTWEKRAKKI 288
Cdd:cd04950   315 FYGEA-VLCGDDPDEFSAAIEKALALKG-DARDKRLARALARQESWDERARAM 365
Glyco_trans_1_2 pfam13524
Glycosyl transferases group 1;
202-289 2.68e-12

Glycosyl transferases group 1;


Pssm-ID: 433281 [Multi-domain]  Cd Length: 93  Bit Score: 61.85  E-value: 2.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 202 AISEKYTSP-LKLFEYMASRRPIISSDLPSLREILTE-KEALFFEagNPADLVRAIKKIFEDKDLSEKLSYNAYQKV-KD 278
Cdd:pfam13524   4 NPSRRPDSPnMRVFEAAACGAPLLTDRTPGLEELFEPgEEILLYR--DPEELAEKIRYLLEHPEERRAIAAAGRERVlAE 81

                          90
                  ....*....|.
gi 1087994491 279 YTWEKRAKKII 289
Cdd:pfam13524  82 HTYAHRAEQLL 92
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 6-281 4.23e-12

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 65.84  E-value: 4.23e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491   6 STLSFLFFTKIYLFFRE--YDILYSRELLTGLFFR-------NYFFELHNFLQKPGRFYKFLIFKPRTIFALTGFL---- 72
Cdd:cd03811    65 KLGLLKAILKLKRILKRakPDVVISFLGFATYIVAklaaarsKVIAWIHSSLSKLYYLKKKLLLKLKLYKKADKIVcvsk 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  73 ---KDNLKKTGIADKKIMILPDAVDLAEFSPSLDRegarKKLNLPLDKKIIIYTGSFLFYKwkGIGSLLDAGKLLKD--- 146
Cdd:cd03811   145 gikEDLIRLGPSPPEKIEVIYNPIDIDRIRALAKE----PILNEPEDGPVILAVGRLDPQK--GHDLLIEAFAKLRKkyp 218

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 147 DFLFVLVGGHP--------WEIRKLKERpiplnVLLVSYQKHeiIPYYLKAADIFVIPNekgdaISEKYtsPLKLFEYMA 218
Cdd:cd03811   219 DVKLVILGDGPlreeleklAKELGLAER-----VIFLGFQSN--PYPYLKKADLFVLSS-----RYEGF--PNVLLEAMA 284

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1087994491 219 SRRPIISSDLPSLREILTEKEALFFEAGNPADL----VRAIKKIFEDKDLSEKLSYNAYQKVKDYTW 281
Cdd:cd03811   285 LGTPVVSTDCPGPREILDDGENGLLVPDGDAAAlagiLAALLQKKLDAALRERLAKAQEAVFREYTI 351
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 53-289 8.20e-12

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 65.08  E-value: 8.20e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  53 RFYKFLIFKprtiFALTGFLKDNLKKTGIADK--------KIMILPDAVDLAEFSPSLDRegaRKKLNLPLDKKIIIYTG 124
Cdd:cd03821   139 RIALHLIER----RNLNNAALVHFTSEQEADElrrfglepPIAVIPNGVDIPEFDPGLRD---RRKHNGLEDRRIILFLG 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 125 SfLFYKwKGIGSLLDAGKLLKD---DFLFVLVG----GHPWEIRKLKERPIPLNVLLVSYQKHEIIPYYLKAADIFVIPn 197
Cdd:cd03821   212 R-IHPK-KGLDLLIRAARKLAEqgrDWHLVIAGpddgAYPAFLQLQSSLGLGDRVTFTGPLYGEAKWALYASADLFVLP- 288

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 198 ekgdaiSEKYTSPLKLFEYMASRRPIISSDLPSLREILTEkealffEAG-----NPADLVRAIKKIFEDKDLSEKLSYNA 272
Cdd:cd03821   289 ------SYSENFGNVVAEALACGLPVVITDKCGLSELVEA------GCGvvvdpNVSSLAEALAEALRDPADRKRLGEMA 356

                         250       260
                  ....*....|....*....|
gi 1087994491 273 ---YQKVKDYTWEKRAKKII 289
Cdd:cd03821   357 rraRQVEENFSWEAVAGQLG 376
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 42-283 4.93e-11

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 62.64  E-value: 4.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  42 FELHNFLQKPGRFYKFLIFKPRTIFALTGflKDNLKKTGIADKKIMILPDAVDLAEFSPSLDREGarkklnlpldkKIII 121
Cdd:cd03820   119 YEAYNKGLRRLLLRRLLYKRADKIVVLTE--ADKLKKYKQPNSNVVVIPNPLSFPSEEPSTNLKS-----------KRIL 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 122 YTGSFLFYKwkGIGSLLDAGKLLKDDFL---FVLVGGHPWEIR--------KLKERpiplnVLLVSYQKHeIIPYYLKAA 190
Cdd:cd03820   186 AVGRLTYQK--GFDLLIEAWALIAKKHPdwkLRIYGDGPEREEleklidklGLEDR-----VKLLGPTKN-IAEEYANSS 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 191 dIFVIpnekgdaisekyTS-----PLKLFEYMASRRPIISSDLPS-LREILTEKE-ALFFEAGNPADLVRAIKKIFEDKD 263
Cdd:cd03820   258 -IFVL------------SSryegfPMVLLEAMAYGLPIISFDCPTgPSEIIEDGEnGLLVPNGDVDALAEALLRLMEDEE 324

                         250       260
                  ....*....|....*....|
gi 1087994491 264 LSEKLSYNAYQKVKDYTWEK 283
Cdd:cd03820   325 LRKKMGKNARKNAERFSIEK 344
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 84-278 1.26e-10

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 61.14  E-value: 1.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  84 KKIMILPDAVDlaEFSPSLDREGARKKLNLPLDKKIIIYTGSFLFYKwkGIGSLLDAGKLLKddflFVLVGGHPWEIRKL 163
Cdd:cd03795   160 NKVRVIPLGID--KNVYNIPRVDFENIKREKKGKKIFLFIGRLVYYK--GLDYLIEAAQYLN----YPIVIGGEGPLKPD 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 164 KERPIPLNVL----LVSYQKHEIIPYYLKAADIFVIP-NEKGDAISekytspLKLFEYMASRRPIISSDLPS--LREILT 236
Cdd:cd03795   232 LEAQIELNLLdnvkFLGRVDDEEKVIYLHLCDVFVFPsVLRSEAFG------IVLLEAMMCGKPVISTNIGTgvPYVNNN 305

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1087994491 237 EKEALFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKD 278
Cdd:cd03795   306 GETGLVVPPKDPDALAEAIDKLLSDEELRESYGENAKKRFEE 347
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 186-279 4.74e-10

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 60.04  E-value: 4.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 186 YLKAADIFVIpnekgDAISEKYtsPLKLFEYMASRRPIISSDLPSLREILTEKEALFFEAG------NPADLVRAIKKIF 259
Cdd:cd03813   367 YYPKLGLLVL-----TSISEGQ--PLVILEAMASGVPVVATDVGSCRELIYGADDALGQAGlvvppaDPEALAEALIKLL 439

                          90       100
                  ....*....|....*....|
gi 1087994491 260 EDKDLSEKLSYNAYQKVKDY 279
Cdd:cd03813   440 RDPELRQAFGEAGRKRVEKY 459
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 20-269 1.41e-08

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 55.15  E-value: 1.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  20 FREYDILYSRELLTGLFFRNYFFELH-NFLQKPGRFYkflifkprtiFALTGFLKDNLKKTGIADKKIMILPDAVDLAEF 98
Cdd:cd05844   111 FHGFDITTSRAWLAASPGWPSQFQRHrRALQRPAALF----------VAVSGFIRDRLLARGLPAERIHVHYIGIDPAKF 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  99 SPSLDREGARKklnlpldkkiIIYTGSFLfyKWKGIGSLLDAGKLLKD---DFLFVLVGGHPwEIRKLKERPIPL-NVLL 174
Cdd:cd05844   181 APRDPAERAPT----------ILFVGRLV--EKKGCDVLIEAFRRLAArhpTARLVIAGDGP-LRPALQALAAALgRVRF 247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 175 VSYQKHEIIPYYLKAADIFVIPN---EKGDaiSEKYtsPLKLFEYMASRRPIISSDLPSLRE-ILTEKEALFFEAGNPAD 250
Cdd:cd05844   248 LGALPHAEVQDWMRRAEIFCLPSvtaASGD--SEGL--GIVLLEAAACGVPVVSSRHGGIPEaILDGETGFLVPEGDVDA 323

                         250
                  ....*....|....*....
gi 1087994491 251 LVRAIKKIFEDKDLSEKLS 269
Cdd:cd05844   324 LADALQALLADRALADRMG 342
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 56-272 2.76e-08

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 54.28  E-value: 2.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  56 KFLIFKPRTIFALTGFLKDNLKKTGIADKKIMILPDAVDLAEFSPSLDREGARKKLNLPlDKKIIIYTGSF--------- 126
Cdd:cd04962   136 RFSINKSDRVTAVSSSLRQETYELFDVDKDIEVIHNFIDEDVFKRKPAGALKRRLLAPP-DEKVVIHVSNFrpvkriddv 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 127 --LFYKW-KGIGSLLdagkllkddflfVLVGGHPwEIRKLKERPIPLNVL--LVSYQKHEIIPYYLKAADIFVIPnekgd 201
Cdd:cd04962   215 vrVFARVrRKIPAKL------------LLVGDGP-ERVPAEELARELGVEdrVLFLGKQDDVEELLSIADLFLLP----- 276

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1087994491 202 aiSEKYTSPLKLFEYMASRRPIISSDLPSLREILTEKEALF-FEAGNPADLVRAIKKIFEDKDLSEKLSYNA 272
Cdd:cd04962   277 --SEKESFGLAALEAMACGVPVVSSNAGGIPEVVKHGETGFlSDVGDVDAMAKSALSILEDDELYNRMGRAA 346
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 132-237 9.95e-08

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 51.64  E-value: 9.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 132 KGIGSLLDAGKLLK---DDFLFVLVGGHPW----EIRKLKERPIPLNVLLVSYQKHEIIPYYLKAADIFVIPnekgdAIS 204
Cdd:cd01635   123 KGIDLLLEALALLKarlPDLVLVLVGGGGEreeeEALAAALGLLERVVIIGGLVDDEVLELLLAAADVFVLP-----SRS 197

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1087994491 205 EkyTSPLKLFEYMASRRPIISSDLPSLREILTE 237
Cdd:cd01635   198 E--GFGLVLLEAMAAGKPVIATDVGGIPEFVVD 228
PRK15484 PRK15484
lipopolysaccharide N-acetylglucosaminyltransferase;
71-291 4.13e-07

lipopolysaccharide N-acetylglucosaminyltransferase;


Pssm-ID: 185381 [Multi-domain]  Cd Length: 380  Bit Score: 50.56  E-value: 4.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  71 FLKDNLKKTgIADKKIMILPDAVDLAEFSPSLdREGARKKLNLPLDKKIIIYTGSflFYKWKGIGSLLDA-GKLLK--DD 147
Cdd:PRK15484  149 FLKKFYEER-LPNADISIVPNGFCLETYQSNP-QPNLRQQLNISPDETVLLYAGR--ISPDKGILLLMQAfEKLATahSN 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 148 FLFVLVG-----------GHPWEIRKLKERPIPLNVLLVSYQKHEIIPYYlKAADIFVIPNEKGDAISekytspLKLFEY 216
Cdd:PRK15484  225 LKLVVVGdptasskgekaAYQKKVLEAAKRIGDRCIMLGGQPPEKMHNYY-PLADLVVVPSQVEEAFC------MVAVEA 297

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1087994491 217 MASRRPIISSDLPSLREILTEKEALFF--EAGNPADLVRAIKKIFEDKDLSEkLSYNAYQKVKD-YTWEKRAKKiiFE 291
Cdd:PRK15484  298 MAAGKPVLASTKGGITEFVLEGITGYHlaEPMTSDSIISDINRTLADPELTQ-IAEQAKDFVFSkYSWEGVTQR--FE 372
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 72-288 4.18e-07

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 50.86  E-value: 4.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  72 LKDNLKKTGIAD-KKIMILPDAVDLAEFSPSLDREGARKKL-NLPLDKKIIIYTGSFLFYKwkgigSLLDAGKLLKD--D 147
Cdd:PLN02871  216 LGKELEAAGVTAaNRIRVWNKGVDSESFHPRFRSEEMRARLsGGEPEKPLIVYVGRLGAEK-----NLDFLKRVMERlpG 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 148 FLFVLVGGHPWEiRKLKERPIPLNVLLVSYQKHEIIPYYLKAADIFVIPNEkgdaiSEkyTSPLKLFEYMASRRPIISSD 227
Cdd:PLN02871  291 ARLAFVGDGPYR-EELEKMFAGTPTVFTGMLQGDELSQAYASGDVFVMPSE-----SE--TLGFVVLEAMASGVPVVAAR 362

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1087994491 228 LPSLREILTE----KEALFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKVKDYTWEKRAKKI 288
Cdd:PLN02871  363 AGGIPDIIPPdqegKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAAREEVEKWDWRAATRKL 427
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
 85-276 3.58e-06

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 47.74  E-value: 3.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  85 KIMILPDAVDLAEFSPslDREGARKKLN---LPLDKKIIIYTGSFLfYKWKGIGSLLDA-GKLLK--DDFLFVLVGG--- 155
Cdd:cd03818   180 RISVIHDGVDTDRLAP--DPAARLRLLNgteLKAGDPVITYVARNL-EPYRGFHVFMRAlPRIQArrPDARVVVVGGdgv 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 156 -----HP----WEIRKLKERPIPLN-VLLVSYQKHEIIPYYLKAADIFVIPnekgdaiSEKYTSPLKLFEYMASRRPIIS 225
Cdd:cd03818   257 sygspPPdggsWKQKMLAELGVDLErVHFVGKVPYDQYVRLLQLSDAHVYL-------TYPFVLSWSLLEAMACGCPVIG 329

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1087994491 226 SDLPSLREILTEKE-ALFFEAGNPADLVRAIKKIFEDKDLSEKLSYNAYQKV 276
Cdd:cd03818   330 SDTAPVREVIRDGRnGLLVDFFDPDALAAAVLELLEDPDRAAALRRAARRTV 381
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 53-268 1.69e-05

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 45.90  E-value: 1.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  53 RFYKFLIFKPRTI----------------FALTGFLKDN------------LKKTGIADKKIMILPDAVDLAEFSPSLD- 103
Cdd:cd04951    95 RFLRMLYPIPLLIctahnkneggrirmfiYRLTDFLCDIttnvsrealdefIAKKAFSKNKSVPVYNGIDLNKFKKDINv 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 104 REGARKKLNLPLDKKIIIYTGSFLfyKWKGIGSLLDAGK---LLKDDFLFVLVGGHPWE---IRKLKERPIPLNVLLVSY 177
Cdd:cd04951   175 RLKIRNKLNLKNDEFVILNVGRLT--EAKDYPNLLLAISeliLSKNDFKLLIAGDGPLRnelERLICNLNLVDRVILLGQ 252

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 178 QKHeiIPYYLKAADIFVIPnekgdaiSEKYTSPLKLFEYMASRRPIISSDLPSLREILTEKEALfFEAGNPADLVRAIKK 257
Cdd:cd04951   253 ISN--ISEYYNAADLFVLS-------SEWEGFGLVVAEAMACERPVVATDAGGVAEVVGDHNYV-VPVSDPQLLAEKIKE 322

                         250
                  ....*....|.
gi 1087994491 258 IFEDKDLSEKL 268
Cdd:cd04951   323 IFDMSDEERDI 333
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
 83-289 1.72e-04

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 42.66  E-value: 1.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491  83 DKKIMILPDAVDLAEFSPSLDREGARKKLNLPLDKKIIIYTGSFLFYKWKGIgsLLD-AGKLLK--DDFLFVLVGGHPWE 159
Cdd:cd03812   157 NGKFKVIPNGIDIEKYKFNKEKRRKRRKLLILEDKLVLGHVGRFNEQKNHSF--LIDiFEELKKknPNVKLVLVGEGELK 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1087994491 160 ---IRKLKERPIPLNVLLVSYQKHeiIPYYLKAADIFVIPnekgdaiSEKYTSPLKLFEYMASRRPIISSDLPSLREILT 236
Cdd:cd03812   235 ekiKEKVKELGLEDKVIFLGFRND--VSEILSAMDVFLFP-------SLYEGLPLVAVEAQASGLPCLLSDTITKECDIT 305

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1087994491 237 EKEAlFFEAGNPADL-VRAIKKIFEDKDLSEKLsYNAYQKVKDYTWEKRAKKII 289
Cdd:cd03812   306 NNVE-FLPLNETPSTwAEKILKLIKRKRRINKE-INKEKKELGYDDESLELTLL 357
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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