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Conserved domains on  [gi|1113398471|gb|OJW61367|]
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hypothetical protein BGO55_32840 [Sphingobacteriales bacterium 50-39]

Protein Classification

DMT family transporter( domain architecture ID 11430850)

DMT (drug/metabolite transporter) family transporter is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others

Gene Ontology:  GO:0016020|GO:0055085|GO:0022857
PubMed:  11432728
TCDB:  2.A.7

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
1-298 2.68e-31

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


:

Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 118.41  E-value: 2.68e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471   1 MAGFLISFTGAILFSTKAIIIKKAFQTtsVDALTLLSLRMLFSLPFyVAAAVWSFRRSATRMTPRQWMWVVILGILGYHL 80
Cdd:COG0697     2 LRGILLLLLAALLWGSSFVAIKLALAG--LPPLQLAFLRFLLAALL-LLPLLLLRGRRLPPLSRRDWLLLLLRGLLGLAL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471  81 SSYFDFVGLQYISAGLERLILFLYPSFAVLINSFAFRQRISRPQIWALLLTYTGIGIAYFGElkiDTGNAHFYWGSFLVF 160
Cdd:COG0697    79 AFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPG---GGGGGGSLLGDLLAL 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471 161 LCAITYAFYLAGMGRIVSVLEPSKFTTYSMLVAVGSVFLHFLVRGgltgnfhlPAAAASGNLWVYGVLLALVATVIPSFM 240
Cdd:COG0697   156 LAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLTG--------LPLPLSAAAWLALLYLGLFGTALAYLL 227
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1113398471 241 LSEGMKRIGANNAAIVTSVGPVSTILQAHFVLGDPIFIEQVVGTLLVIAGVLLTGWKA 298
Cdd:COG0697   228 WFRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRE 285
 
Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
1-298 2.68e-31

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 118.41  E-value: 2.68e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471   1 MAGFLISFTGAILFSTKAIIIKKAFQTtsVDALTLLSLRMLFSLPFyVAAAVWSFRRSATRMTPRQWMWVVILGILGYHL 80
Cdd:COG0697     2 LRGILLLLLAALLWGSSFVAIKLALAG--LPPLQLAFLRFLLAALL-LLPLLLLRGRRLPPLSRRDWLLLLLRGLLGLAL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471  81 SSYFDFVGLQYISAGLERLILFLYPSFAVLINSFAFRQRISRPQIWALLLTYTGIGIAYFGElkiDTGNAHFYWGSFLVF 160
Cdd:COG0697    79 AFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPG---GGGGGGSLLGDLLAL 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471 161 LCAITYAFYLAGMGRIVSVLEPSKFTTYSMLVAVGSVFLHFLVRGgltgnfhlPAAAASGNLWVYGVLLALVATVIPSFM 240
Cdd:COG0697   156 LAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLTG--------LPLPLSAAAWLALLYLGLFGTALAYLL 227
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1113398471 241 LSEGMKRIGANNAAIVTSVGPVSTILQAHFVLGDPIFIEQVVGTLLVIAGVLLTGWKA 298
Cdd:COG0697   228 WFRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRE 285
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
154-296 5.81e-08

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 50.66  E-value: 5.81e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471 154 WGSFLVFLCAITYAFYLAGMGRIVSVLEPSKFTTYSMLVAvGSVFLHFLVRGGLTGNFHLPAaaasgnlWVYGVLLALVA 233
Cdd:pfam00892   2 KGILLALLAALIWAIYFVFSKILLRRISPLTLTFWRFLIA-GILLLPFALFTGGKLVIPLKS-------WLALLYLGVLG 73
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1113398471 234 TVIPSFMLSEGMKRIGANNAAIVTSVGPVSTILQAHFVLGDPIFIEQVVGTLLVIAGVLLTGW 296
Cdd:pfam00892  74 TFLGFLLYFYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLILL 136
 
Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
1-298 2.68e-31

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 118.41  E-value: 2.68e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471   1 MAGFLISFTGAILFSTKAIIIKKAFQTtsVDALTLLSLRMLFSLPFyVAAAVWSFRRSATRMTPRQWMWVVILGILGYHL 80
Cdd:COG0697     2 LRGILLLLLAALLWGSSFVAIKLALAG--LPPLQLAFLRFLLAALL-LLPLLLLRGRRLPPLSRRDWLLLLLRGLLGLAL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471  81 SSYFDFVGLQYISAGLERLILFLYPSFAVLINSFAFRQRISRPQIWALLLTYTGIGIAYFGElkiDTGNAHFYWGSFLVF 160
Cdd:COG0697    79 AFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPG---GGGGGGSLLGDLLAL 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471 161 LCAITYAFYLAGMGRIVSVLEPSKFTTYSMLVAVGSVFLHFLVRGgltgnfhlPAAAASGNLWVYGVLLALVATVIPSFM 240
Cdd:COG0697   156 LAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLTG--------LPLPLSAAAWLALLYLGLFGTALAYLL 227
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1113398471 241 LSEGMKRIGANNAAIVTSVGPVSTILQAHFVLGDPIFIEQVVGTLLVIAGVLLTGWKA 298
Cdd:COG0697   228 WFRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRE 285
RhtA COG5006
Threonine/homoserine efflux transporter RhtA [Amino acid transport and metabolism];
1-299 2.38e-18

Threonine/homoserine efflux transporter RhtA [Amino acid transport and metabolism];


Pssm-ID: 444030 [Multi-domain]  Cd Length: 290  Bit Score: 83.33  E-value: 2.38e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471   1 MAGFLISFTGAILFSTKAIIIKKAFQTtsVDALTLLSLRMLFSLPFYVAAavwsFRRSATRMTPRQWMWVVILGILgYHL 80
Cdd:COG5006     8 LPGVLLVLLSALSVQLGAALAKLLFPG--VGPLGVTALRLAFAALILLLI----FRPWRRRLTRRDWLALLLYGVA-LAG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471  81 SSYFDFVGLQYISAGLERLILFLYPSFAVLINSFAFRQRIsrpqiWALLltyTGIGIAYFGELKiDTGNAHFYWGSFLVF 160
Cdd:COG5006    81 MNLLFYLAIARIPLGIAVALEFLGPLAVALLGSRRRRDLL-----WVAL---ALAGVVLLLPVG-LSGGSLDPVGVLFAL 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471 161 LCAITYAFYLAGMGRIVSVLEPSKFTTYSMLVAvgSVFLhflvrgGLTGNFHLPAAAASGNLWVYGVLLALVATVIPSFM 240
Cdd:COG5006   152 GAAACWALYILLGRRVGARLPGLTGLALGMLVA--ALVL------LPFGLPTAGPALLDPPVLLLGLGVAVLSSVLPYSL 223
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1113398471 241 LSEGMKRIGANNAAIVTSVGPVSTILQAHFVLGDPIFIEQVVGTLLVIAGVLLTGWKAS 299
Cdd:COG5006   224 EMVALRRLPARTFGILMSLEPAVAALAGWLVLGEVLTPLQWLGIALVVAASAGATLTAR 282
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
154-296 5.81e-08

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 50.66  E-value: 5.81e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471 154 WGSFLVFLCAITYAFYLAGMGRIVSVLEPSKFTTYSMLVAvGSVFLHFLVRGGLTGNFHLPAaaasgnlWVYGVLLALVA 233
Cdd:pfam00892   2 KGILLALLAALIWAIYFVFSKILLRRISPLTLTFWRFLIA-GILLLPFALFTGGKLVIPLKS-------WLALLYLGVLG 73
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1113398471 234 TVIPSFMLSEGMKRIGANNAAIVTSVGPVSTILQAHFVLGDPIFIEQVVGTLLVIAGVLLTGW 296
Cdd:pfam00892  74 TFLGFLLYFYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLILL 136
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
1-140 1.39e-05

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 44.11  E-value: 1.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471   1 MAGFLISFTGAILFSTKAIIIKKAFQTtsVDALTLLSLRMLFSLPFYVAAAVwsFRRSATRMTPRQWMWVVILGILGYHL 80
Cdd:pfam00892   1 LKGILLALLAALIWAIYFVFSKILLRR--ISPLTLTFWRFLIAGILLLPFAL--FTGGKLVIPLKSWLALLYLGVLGTFL 76
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471  81 SSYFDFVGLQYISAGLERLILFLYPSFAVLINSFAFRQRISRPQIWALLLTYTGIGIAYF 140
Cdd:pfam00892  77 GFLLYFYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLILL 136
RarD COG2962
Membrane protein RarD, contains two EamA domains, drug/metabolite transporter family [General ...
30-296 4.00e-05

Membrane protein RarD, contains two EamA domains, drug/metabolite transporter family [General function prediction only];


Pssm-ID: 442202 [Multi-domain]  Cd Length: 297  Bit Score: 44.34  E-value: 4.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471  30 VDALTLLSLRMLFSLPFYVAAAVWSFRRSATRM---TPRQWMWVVILGILgyhlssyfdfVGLQ---YISAGLERLIL-- 101
Cdd:COG2962    32 VPALEILAHRILWSLPFLLLLLLLTRRWGELRRllrDPRLLLLLLLAALL----------IAVNwllFIWAVNNGHVLea 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471 102 ----FLYPSFAVLINSFAFRQRISRPQIWALLLTYTGIGIayfgeLKIDTGnaHFYWGSFLVflcAITYAFY-----LAG 172
Cdd:COG2962   102 slgyFINPLVSVLLGVLFLKERLRRLQWLAVGLAAAGVLV-----LTVGYG--SLPWIALVL---ALSFGLYgllrkKLP 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471 173 MGRIVSV-LEpskfTTYSMLVAVGsvflhFLVRGGLTGNFHLPAAAASGNLWvygVLLALVATVIPSFMLSEGMKRIGAN 251
Cdd:COG2962   172 VDALTGLtLE----TLLLLPLALA-----YLLWLAATGTGAFGSAGPGLTLL---LLLAGVVTAVPLLLFAAAARRLPLS 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1113398471 252 NAAIVTSVGPVSTILQAHFVLGDPIFIEQVVGTLLVIAGVLLTGW 296
Cdd:COG2962   240 TLGLLQYIAPTLQFLLAVFVFGEPFTPARLITFGLIWLALALFSL 284
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
155-301 3.60e-03

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 38.28  E-value: 3.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113398471 155 GSFLVFLCAITYAFYLAGMGRIVSVLEPSKFTTYSMLVAVGSVFLHFLVRGGltgnfhlPAAAASGNLWVYGVLLALVAT 234
Cdd:COG0697     4 GILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLRGR-------RLPPLSRRDWLLLLLRGLLGL 76
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1113398471 235 VIPSFMLSEGMKRIGANNAAIVTSVGPVSTILQAHFVLGDPIFIEQVVGTLLVIAGVLLTGWKASSG 301
Cdd:COG0697    77 ALAFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGG 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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