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Conserved domains on  [gi|1113580614|gb|OJY40205|]
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hypothetical protein BGP06_17375 [Rhizobiales bacterium 65-9]

Protein Classification

type 1 periplasmic-binding domain-containing protein( domain architecture ID 70)

type 1 periplasmic-binding domain-containing protein such as the ligand binding domains of the LacI family of transcriptional regulators, the ABC transporter substrate-binding proteins, the family C GPCRs, membrane bound guanylyl cyclases including the family of natriuretic peptide receptors (NPRs), and the N-terminal LIVBP-like domains of the ionotropic glutamate receptors (iGluRs); contains the Venus flytrap-like domain which undergoes transition from an open to a closed conformational state upon ligand binding

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Periplasmic_Binding_Protein_type1 super family cl10011
Type 1 periplasmic binding fold superfamily; Type 1 periplasmic binding fold superfamily. This ...
 31-385 2.98e-77

Type 1 periplasmic binding fold superfamily; Type 1 periplasmic binding fold superfamily. This model and hierarchy represent the ligand binding domains of the LacI family of transcriptional regulators, periplasmic binding proteins of the ABC-type transport systems, the family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases including the family of natriuretic peptide receptors (NPRs), and the N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domains of the ionotropic glutamate receptors (iGluRs). In LacI-like transcriptional regulator and the bacterial periplasmic binding proteins, the ligands are monosaccharides, including lactose, ribose, fructose, xylose, arabinose, galactose/glucose and other sugars, with a few exceptions. Periplasmic sugar binding proteins are one of the components of ABC transporters and are involved in the active transport of water-soluble ligands. The LacI family of proteins consists of transcriptional regulators related to the lac repressor. In this case, the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes. The core structures of periplasmic binding proteins are classified into two types, and they differ in number and order of beta strands: type 1 has six beta strands while type 2 has five beta strands per sub-domain. These two structural folds are thought to be distantly related via a common ancestor. Notably, while the N-terminal LIVBP-like domain of iGluRs belongs to the type 1 periplasmic-binding fold protein superfamily, the glutamate-binding domain of the iGluR is structurally similar to the type 2 periplasmic-binding fold.


The actual alignment was detected with superfamily member cd06348:

Pssm-ID: 471960 [Multi-domain]  Cd Length: 342  Bit Score: 242.14  E-value: 2.98e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQTNQA 109
Cdd:cd06348     1 KIGVALSLTGPGALYGQSQKNGAQLAVEEINAAGGVGGVKIELIVEDTAGDPEQAINAFQKLiNQDKVLAILGPTLSSEA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAEnRPYAFRNSALLQVITDDMVAQVRKDYpNAKRVVMVTDPKDAiQKFFATVAAP 189
Cdd:cd06348    81 FAADPIAQQAKVPVVGISNTAPGITDI-GPYIFRNSLPEDKVIPPTVKAAKKKY-GIKKVAVLYDQDDA-FTVSGTKVFP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 190 PALTAAGFEIVNKDSYIEipyTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGWILEPVARA 269
Cdd:cd06348   158 AALKKNGVEVLDTETFQT---GDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPDLIKL 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 270 AGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEARlpgqytlPAYYDAGAYETVYMFADVLKKSGLKPdaDVQALRSA 347
Cdd:cd06348   235 AGKAAegVIVGSAWSPDNPDPKNQAFVAAYKEKYGKE-------PDQFAAQAYDAAYILAEAIKKAGSTT--DRADLRDA 305

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1113580614 348 LRDGLQSmKDFPGLGNKITINQEGDAIKPTLIYKTNGG 385
Cdd:cd06348   306 LARILIA-KDFEGPLGPFSFDADRDGIQPPVVLIVKDG 342
 
Name Accession Description Interval E-value
PBP1_ABC_HAAT-like cd06348
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-385 2.98e-77

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380571 [Multi-domain]  Cd Length: 342  Bit Score: 242.14  E-value: 2.98e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQTNQA 109
Cdd:cd06348     1 KIGVALSLTGPGALYGQSQKNGAQLAVEEINAAGGVGGVKIELIVEDTAGDPEQAINAFQKLiNQDKVLAILGPTLSSEA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAEnRPYAFRNSALLQVITDDMVAQVRKDYpNAKRVVMVTDPKDAiQKFFATVAAP 189
Cdd:cd06348    81 FAADPIAQQAKVPVVGISNTAPGITDI-GPYIFRNSLPEDKVIPPTVKAAKKKY-GIKKVAVLYDQDDA-FTVSGTKVFP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 190 PALTAAGFEIVNKDSYIEipyTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGWILEPVARA 269
Cdd:cd06348   158 AALKKNGVEVLDTETFQT---GDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPDLIKL 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 270 AGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEARlpgqytlPAYYDAGAYETVYMFADVLKKSGLKPdaDVQALRSA 347
Cdd:cd06348   235 AGKAAegVIVGSAWSPDNPDPKNQAFVAAYKEKYGKE-------PDQFAAQAYDAAYILAEAIKKAGSTT--DRADLRDA 305

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1113580614 348 LRDGLQSmKDFPGLGNKITINQEGDAIKPTLIYKTNGG 385
Cdd:cd06348   306 LARILIA-KDFEGPLGPFSFDADRDGIQPPVVLIVKDG 342
LivK COG0683
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ...
 27-391 1.35e-53

ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];


Pssm-ID: 440447 [Multi-domain]  Cd Length: 314  Bit Score: 180.13  E-value: 1.35e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  27 QQPYKIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQ 105
Cdd:COG0683     1 ADPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAAGGVLGRKIELVVEDDASDPDTAVAAARKLiDQDKVDAIVGPLS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 106 TNQARVAFSATNREKLVSLTPGSNVPGLA-AENRPYAFRNSALLQVITDDMVAQVRKDYpNAKRVVMVTDPKDAIQKFFA 184
Cdd:COG0683    81 SGVALAVAPVAEEAGVPLISPSATAPALTgPECSPYVFRTAPSDAQQAEALADYLAKKL-GAKKVALLYDDYAYGQGLAA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 185 TVAAppALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVitptgwile 264
Cdd:COG0683   160 AFKA--ALKAAGGEVVGEEYY---PPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKGPL--------- 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 265 pvaraagdivvycgtsfdpyqddahVKAFNAEFKKRVEARlpgqytlPAYYDAGAYETVYMFADVLKKSGlkpDADVQAL 344
Cdd:COG0683   226 -------------------------NKAFVKAYKAKYGRE-------PSSYAAAGYDAALLLAEAIEKAG---STDREAV 270

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1113580614 345 RSALRDGlqsmkDFPGLGNKITINQEGDAIKPTLIYK-TNGGQWARAK 391
Cdd:COG0683   271 RDALEGL-----KFDGVTGPITFDPDGQGVQPVYIVQvKADGKFVVVE 313
Peripla_BP_6 pfam13458
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ...
 29-349 2.24e-45

Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.


Pssm-ID: 433225 [Multi-domain]  Cd Length: 342  Bit Score: 159.36  E-value: 2.24e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  29 PYKIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQTN 107
Cdd:pfam13458   1 PIKIGVLTPLSGPYASSGKSSRAGARAAIEEINAAGGVNGRKIELVVADDQGDPDVAAAAARRLvDQDGVDAIVGGVSSA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 108 QARVAFSATNREKLVSLTPGSNVPGLAAenrPYAFRNSALLQVITDDMVAQVRKDYPnAKRVVMVTDPKDAIQKFFATVA 187
Cdd:pfam13458  81 VALAVAEVLAKKGVPVIGPAALTGEKCS---PYVFSLGPTYSAQATALGRYLAKELG-GKKVALIGADYAFGRALAAAAK 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 188 AppALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLK---TPVITPTGWIlE 264
Cdd:pfam13458 157 A--AAKAAGGEVVGEVRY---PLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDakgIKLVGLGGDE-P 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 265 PVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEARLPGQYTlpayydAGAYETVYMFADVLKKSGlkpDADVQ 342
Cdd:pfam13458 231 DLKALGGDAAegVYATVPFFPDLDNPATRAFVAAFAAKYGEAPPTQFA------AGGYIAADLLLAALEAAG---SPTRE 301


                  ....*..
gi 1113580614 343 ALRSALR 349
Cdd:pfam13458 302 AVIAALR 308
PRK15404 PRK15404
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
19-343 2.22e-16

high-affinity branched-chain amino acid ABC transporter substrate-binding protein;


Pssm-ID: 237959 [Multi-domain]  Cd Length: 369  Bit Score: 79.68  E-value: 2.22e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  19 SLGGAAIAQQpYKIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARAGVV 98
Cdd:PRK15404   16 ALSHAALADD-IKIAIVGPMSGPVAQYGDMEFTGARQAIEDINAKGGIKGDKLEGVEYDDACDPKQAVAVANKVVNDGIK 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  99 GIIGPLQTNQARVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSALlqvitDDM----VAQVRKDYPNAKRVVMVTD 174
Cdd:PRK15404   95 YVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLIFRTIGL-----DSDqgptAAKYILEKVKPKRIAVLHD 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 175 PKDAIQKFFATVAAppALTAAGFEIVNKDSyieIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTP 254
Cdd:PRK15404  170 KQQYGEGLARSVKD--GLKKAGANVVFFEG---ITAGDKDFSALIAKLKKENVDFVYYGGYHPEMGQILRQAREAGLKTQ 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 255 VITPTGWILEPVARAAGD----IVVYCGTSFDpyQDDAH---VKAFNAefKKRVEArlpGQYTLPayydagAYETVYMFA 327
Cdd:PRK15404  245 FMGPEGVGNKSLSNIAGPasegMLVTLPKRYD--QDPANkaiVDAFKA--KKQDPS---GPFVWT------TYAAVQSLA 311

                         330
                  ....*....|....*.
gi 1113580614 328 DVLKKSGLKPDADVQA 343
Cdd:PRK15404  312 AGINRAGSDDPAKVAK 327
 
Name Accession Description Interval E-value
PBP1_ABC_HAAT-like cd06348
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-385 2.98e-77

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380571 [Multi-domain]  Cd Length: 342  Bit Score: 242.14  E-value: 2.98e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQTNQA 109
Cdd:cd06348     1 KIGVALSLTGPGALYGQSQKNGAQLAVEEINAAGGVGGVKIELIVEDTAGDPEQAINAFQKLiNQDKVLAILGPTLSSEA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAEnRPYAFRNSALLQVITDDMVAQVRKDYpNAKRVVMVTDPKDAiQKFFATVAAP 189
Cdd:cd06348    81 FAADPIAQQAKVPVVGISNTAPGITDI-GPYIFRNSLPEDKVIPPTVKAAKKKY-GIKKVAVLYDQDDA-FTVSGTKVFP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 190 PALTAAGFEIVNKDSYIEipyTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGWILEPVARA 269
Cdd:cd06348   158 AALKKNGVEVLDTETFQT---GDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPDLIKL 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 270 AGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEARlpgqytlPAYYDAGAYETVYMFADVLKKSGLKPdaDVQALRSA 347
Cdd:cd06348   235 AGKAAegVIVGSAWSPDNPDPKNQAFVAAYKEKYGKE-------PDQFAAQAYDAAYILAEAIKKAGSTT--DRADLRDA 305

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1113580614 348 LRDGLQSmKDFPGLGNKITINQEGDAIKPTLIYKTNGG 385
Cdd:cd06348   306 LARILIA-KDFEGPLGPFSFDADRDGIQPPVVLIVKDG 342
PBP1_ABC_LivK_ligand_binding-like cd06347
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-381 1.38e-60

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380570 [Multi-domain]  Cd Length: 334  Bit Score: 198.92  E-value: 1.38e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd06347     1 KIGVIGPLTGEAAAYGQPALNGAELAVDEINAAGGILGKKIELIVYDNKSDPTEAANAAQKLIdEDKVVAIIGPVTSSIA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLaAENRPYAFRNSallqvITDD----MVAQVRKDYPNAKRVVMVTDPKDA----IQK 181
Cdd:cd06347    81 LAAAPIAQKAKIPMITPSATNPLV-TKGGDYIFRAC-----FTDPfqgaALAKFAYEELGAKKAAVLYDVSSDyskgLAK 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 182 FFATvaappALTAAGFEIVNKDSYIEipyTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGW 261
Cdd:cd06347   155 AFKE-----AFEKLGGEIVAEETYTS---GDTDFSAQLTKIKAANPDVIFLPGYYEEAALIIKQARELGITAPILGGDGW 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 262 ---ILEPVARAAGDIVVYCgTSFDPYQDDAHVKAFNAEFKKRvearlpgqY-TLPAYYDAGAYETVYMFADVLKKSGlkp 337
Cdd:cd06347   227 dspELLELGGDAVEGVYFT-THFSPDDPSPEVQEFVKAYKAK--------YgEPPNAFAALGYDAVMLLADAIKRAG--- 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1113580614 338 DADvqalRSALRDGLQSMKDFPGLGNKITINQEGDAIKPTLIYK 381
Cdd:cd06347   295 STD----PEAIRDALAKTKDFEGVTGTITFDPNGNPIKPAVILE 334
PBP1_ABC_HAAT-like cd06349
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-387 1.58e-56

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380572 [Multi-domain]  Cd Length: 338  Bit Score: 188.55  E-value: 1.58e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARA-GVVGIIGPLQTNQA 109
Cdd:cd06349     1 KIGVSGPLTGDNAEYGQQFKNGVELAVDEINAAGGVNGRKLELVVYDDQGDPKEAVNIAQKFVSDdKVVAVIGDFSSSCS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENrPYAFRNSALLQVITDDMvAQVRKDYPNAKRVVMV---TDPKDAIQKFFATv 186
Cdd:cd06349    81 MAAAPIYEEAGLVQISPTASHPDFTKGG-DYVFRNSPTQAVEAPFL-ADYAVKKLGAKKIAIIylnTDWGVSAADAFKK- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 187 aappALTAAGFEIVNKDSYIEipyTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGWILEPV 266
Cdd:cd06349   158 ----AAKALGGEIVATEAYLP---GTKDFSAQITKIKNANPDAIYLAAYYNDAALIAKQARQLGWDVQIFGSSSLYSPEF 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 267 ARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRvearlpgqY-TLPAYYDAGAYETVYMFADVLKKSGlkpdadvqA 343
Cdd:cd06349   231 IELAGDAAegVYLSSPFFPESPDPEVKEFVKAYKAK--------YgEDPDDFAARAYDAVNILAEAIEKAG--------T 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1113580614 344 LRSALRDGLQSMKDFPGLGNKITINQEGDAIKPTLIYKTNGGQW 387
Cdd:cd06349   295 DREAIRDALANIKDFSGLTGTITFDENGDVLKSLTILVVKDGKF 338
LivK COG0683
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ...
 27-391 1.35e-53

ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];


Pssm-ID: 440447 [Multi-domain]  Cd Length: 314  Bit Score: 180.13  E-value: 1.35e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  27 QQPYKIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQ 105
Cdd:COG0683     1 ADPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAAGGVLGRKIELVVEDDASDPDTAVAAARKLiDQDKVDAIVGPLS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 106 TNQARVAFSATNREKLVSLTPGSNVPGLA-AENRPYAFRNSALLQVITDDMVAQVRKDYpNAKRVVMVTDPKDAIQKFFA 184
Cdd:COG0683    81 SGVALAVAPVAEEAGVPLISPSATAPALTgPECSPYVFRTAPSDAQQAEALADYLAKKL-GAKKVALLYDDYAYGQGLAA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 185 TVAAppALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVitptgwile 264
Cdd:COG0683   160 AFKA--ALKAAGGEVVGEEYY---PPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKGPL--------- 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 265 pvaraagdivvycgtsfdpyqddahVKAFNAEFKKRVEARlpgqytlPAYYDAGAYETVYMFADVLKKSGlkpDADVQAL 344
Cdd:COG0683   226 -------------------------NKAFVKAYKAKYGRE-------PSSYAAAGYDAALLLAEAIEKAG---STDREAV 270

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1113580614 345 RSALRDGlqsmkDFPGLGNKITINQEGDAIKPTLIYK-TNGGQWARAK 391
Cdd:COG0683   271 RDALEGL-----KFDGVTGPITFDPDGQGVQPVYIVQvKADGKFVVVE 313
PBP1_ABC_ligand_binding-like cd19980
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-379 4.27e-53

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380635 [Multi-domain]  Cd Length: 334  Bit Score: 179.34  E-value: 4.27e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd19980     1 KIGVIAPLSGPVAALGQQVLNGAKLAVEEINAKGGVLGRKLELVVEDDKCPPAEGVAAAKKLItDDKVPAIIGAWCSSVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSAllqviTDDMVAQVRKDY----PNAKRVVMVTDPKD----AIQK 181
Cdd:cd19980    81 LAVMPVAERAKVPLVVEISSAPKITEGGNPYVFRLNP-----TNSMLAKAFAKYladkGKPKKVAFLAENDDygrgAAEA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 182 FfatvaaPPALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGW 261
Cdd:cd19980   156 F------KKALKAKGVKVVATEYF---DQGQTDFTTQLTKLKAANPDAIFVVAETEDGALILKQARELGLKQQLVGTGGT 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 262 ILEPVARAAGDI------VVYCGTSFDPYQDDAHVKAFNAEFKKRvearlpgqytlPAYYDAGAYETVYMFADVLKKSGl 335
Cdd:cd19980   227 TSPDLIKLAGDAaegvygASIYAPTADNPANKAFVAAYKKKYGEP-----------PDKFAALGYDAVMVIAEAIKKAG- 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1113580614 336 kpDADVQALRSALRDGlqsmKDFPGLGNKITINQEGDAIKPTLI 379
Cdd:cd19980   295 --STDPEKIRAAALKK----VDYKGPGGTIKFDEKGQAHKNVVL 332
PBP1_ABC_transporter_LIVBP-like cd06268
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ...
 31-334 4.42e-53

periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.


Pssm-ID: 380492 [Multi-domain]  Cd Length: 298  Bit Score: 178.29  E-value: 4.42e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd06268     1 KIGVVVPLTGPYADYGEEILRGVALAVEEINAAGGINGRKLELVIADDQGDPETAVAVARKLVdDDKVLAVVGHYSSSVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSALLQVITDDMVAQVRKDYpNAKRVVMVTDPKDAIQKFFATVAAp 189
Cdd:cd06268    81 LAAAPIYQEAGIPLISPGSTAPELTEGGGPYVFRTVPSDAMQAAALADYLAKKL-KGKKVAILYDDYDYGKSLADAFKK- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 190 pALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGWILEPVARA 269
Cdd:cd06268   159 -ALKALGGEIVAEEDF---PLGTTDFSAQLTKIKAAGPDVLFLAGYGADAANALKQARELGLKLPILGGDGLYSPELLKL 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1113580614 270 AGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEARlpgqytlPAYYDAGAYETVYMFADVLKKSG 334
Cdd:cd06268   235 GGEAAegVVVAVPWHPDSPDPPKQAFVKAYKKKYGGP-------PSWRAATAYDATQALAGDRVQQP 294
PBP1_ABC_LIVBP-like cd06342
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ...
 31-381 7.92e-47

type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.


Pssm-ID: 380565 [Multi-domain]  Cd Length: 334  Bit Score: 163.08  E-value: 7.92e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARAGVVGIIGPLQTNQAR 110
Cdd:cd06342     1 KIGVAGPLTGPNAALGQDIRNGAELAVDEINAKGGGLGFKIELVAQDDACDPAQAVAAAQKLVADGVVAVIGHYNSGAAI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 111 VAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSAllqviTDDMVAQVRKDYP----NAKRVVMVTDPKD---AIQKFF 183
Cdd:cd06342    81 AAAPIYAEAGIPMISPSATNPKLTEQGYKNFFRVVG-----TDDQQGPAAADYAaktlKAKRVAVIHDGTAygkGLADAF 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 184 ATvaappALTAAGFEIVNKDSyieIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGWIL 263
Cdd:cd06342   156 KK-----ALKALGGTVVGREG---ITPGTTDFSALLTKIKAANPDAVYFGGYYPEAGLLLRQLREAGLKAPFMGGDGIVS 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 264 EPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRvEARLPGQYTLPAyYDAgayetVYMFADVLKKSGlKPDADv 341
Cdd:cd06342   228 PDFIKAAGDAAegVYATTPGAPPEKLPAAKAFLKAYKAK-FGEPPGAYAAYA-YDA-----AQVLLAAIEKAG-STDRA- 298

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1113580614 342 qALRSALRDGlqsmkDFPGLGNKITINQEGDAIKPTL-IYK 381
Cdd:cd06342   299 -AVAAALRAT-----DFDGVTGTISFDAKGDLTGPAFtVYQ 333
Peripla_BP_6 pfam13458
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ...
 29-349 2.24e-45

Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.


Pssm-ID: 433225 [Multi-domain]  Cd Length: 342  Bit Score: 159.36  E-value: 2.24e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  29 PYKIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQTN 107
Cdd:pfam13458   1 PIKIGVLTPLSGPYASSGKSSRAGARAAIEEINAAGGVNGRKIELVVADDQGDPDVAAAAARRLvDQDGVDAIVGGVSSA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 108 QARVAFSATNREKLVSLTPGSNVPGLAAenrPYAFRNSALLQVITDDMVAQVRKDYPnAKRVVMVTDPKDAIQKFFATVA 187
Cdd:pfam13458  81 VALAVAEVLAKKGVPVIGPAALTGEKCS---PYVFSLGPTYSAQATALGRYLAKELG-GKKVALIGADYAFGRALAAAAK 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 188 AppALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLK---TPVITPTGWIlE 264
Cdd:pfam13458 157 A--AAKAAGGEVVGEVRY---PLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDakgIKLVGLGGDE-P 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 265 PVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEARLPGQYTlpayydAGAYETVYMFADVLKKSGlkpDADVQ 342
Cdd:pfam13458 231 DLKALGGDAAegVYATVPFFPDLDNPATRAFVAAFAAKYGEAPPTQFA------AGGYIAADLLLAALEAAG---SPTRE 301


                  ....*..
gi 1113580614 343 ALRSALR 349
Cdd:pfam13458 302 AVIAALR 308
PBP1_ABC_RPA1789-like cd06333
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ...
 31-362 4.82e-42

type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).


Pssm-ID: 380556 [Multi-domain]  Cd Length: 342  Bit Score: 150.39  E-value: 4.82e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLAR-AGVVGIIGPLQTNQA 109
Cdd:cd06333     1 KIGAILSLTGPAASLGIPERNAVELLVEQINAAGGINGRKLELIVYDDESDPTKAVTNARKLIEeDKVDAIIGPSTTGES 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREK--LVSLTPGSNVpglAAENRPYAFR----NSALLQVITDDMVAQvrkdypNAKRVVMVTDPK---DAIQ 180
Cdd:cd06333    81 LAVAPIAEEAKvpLISLAGAAAI---VEPVRKWVFKtpqsDSLVAEAILDYMKKK------GIKKVALLGDSDaygQSGR 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 181 KFFATVAAppaltAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVI---- 256
Cdd:cd06333   152 AALKKLAP-----EYGIEIVADERF---ARTDTDMTAQLTKIRAAKPDAVLVWASGPPAALVAKNLRQLGYKGPIYqshg 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 257 TPTGWILEPVARAAGDIVVYCGTSFDPYQ--DDAHVKAFNAEFKKRVEARlpgqY-TLPAYYDAGAYETVYMFADVLKKS 333
Cdd:cd06333   224 AANQDFIKLAGKAAEGVILPAGKLLVADQlpDSDPQKKVLLEFVKAYEAK----YgEGPSTFAGHAYDALLLLVEAIEPA 299

                         330       340
                  ....*....|....*....|....*....
gi 1113580614 334 GlkpdadvQALRSALRDGLQSMKDFPGLG 362
Cdd:cd06333   300 G-------GTDRAALRDALENTKGLVGVT 321
PBP1_ABC_HAAT-like cd19986
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-327 1.14e-41

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380641 [Multi-domain]  Cd Length: 297  Bit Score: 148.16  E-value: 1.14e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARAG-VVGIIGPLQTNQA 109
Cdd:cd19986     1 KIGVVAPLTGPAALNGEYQKNGAQLALEEINAAGGVLGRPLELVVEDDQGTNTGAVNAVNKLISDDkVVAVIGPHYSTQV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENrPYAFRNSAllqviTDDMVAQVRKDYP----NAKRVVMVTDPKDaiqkfFAT 185
Cdd:cd19986    81 LAVSPLVKEAKIPVITGGTSPKLTEQGN-PYMFRIRP-----SDSVSAKALAKYAveelGAKKIAILYDNDD-----FGT 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 186 VAAP---PALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVlLSIFYDRGVDFLKEAIRQ-GLKTPVITPTGW 261
Cdd:cd19986   150 GGADvvtAALKALGLEPVAVESY---NTGDKDFTAQLLKLKNSGADVI-IAWGHDAEAALIARQIRQlGLDVPVIGSSSF 225

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1113580614 262 ILEPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEaRLPGQYTLpAYYDAgayetVYMFA 327
Cdd:cd19986   226 ATPTVLLLAGEALegIYSVTDFVPSDPDPKVQAFVKKYKAKYG-EDPDLYSA-WYYDA-----MYLLA 286
PBP1_ABC_ligand_binding-like cd06343
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ...
 31-387 3.83e-39

type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.


Pssm-ID: 380566 [Multi-domain]  Cd Length: 355  Bit Score: 143.09  E-value: 3.83e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQTNQA 109
Cdd:cd06343     8 KIGTSLPLSGPAAAYGKPVRAGAAAYFDEVNAAGGINGRKIELIVEDDGYDPARAVAAVRKLvEQDKVFAIVGGLGTPTN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSALLQVITDDMVAQVRKDYPNAKRVVMVTDP---KDAIQkffatv 186
Cdd:cd06343    88 LAVRPYLNEAGVPQLFPATGASALSPPPKPYTFGVQPSYEDEGRILADYIVETLPAAKVAVLYQNDdfgKDGLE------ 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 187 AAPPALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGW----I 262
Cdd:cd06343   162 GLKEALKAYGLEVVAEETY---EPGDTDFSSQVLKLKAAGADVVVLGTLPKEAAAALKEAAKLGWKPTFLGSSVSadptT 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 263 LEPVARAAGDIVVYCGTSFDPYQ-DDAHVKAFNAEFKKRVEARLPGQYTLPAYYDAgayetvYMFADVLKKSGlkPDADv 341
Cdd:cd06343   239 LAKAGGDAAEGVYSASYLKDPTDaDDPAVKEFREAYKKYFPDDPPNAYALYGYAAA------QVFVEALKRAG--KDLT- 309

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 1113580614 342 qalRSALRDGLQSMKDFPGLGNKITIN---QEGDAIKPTLIYKTNGGQW 387
Cdd:cd06343   310 ---REGLIKALESLKDFDDGGPGPPVTfspDDHRGIESMYLVQVDGGKW 355
PBP1_ABC_ligand_binding-like cd06340
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ...
 31-387 9.00e-39

type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.


Pssm-ID: 380563 [Multi-domain]  Cd Length: 352  Bit Score: 141.93  E-value: 9.00e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGG---VNGHPIEFVIEDNQTKPELAVSAVRNLARA-GVVGIIGPLQT 106
Cdd:cd06340     1 KIGVLYPLSGPLALIGQEAKRGAELAVDEINAAGGiksLGGAKIELVVADTQSDPEVAASEAERLITQeGVVAIIGAYSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 107 NQARVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSALLQVITDDMVAQVR----KDYPNAKRVVMVTDPKDAIQKF 182
Cdd:cd06340    81 SVTLAASQVAERYGVPFVTASAVADEITERGFKYVFRTAPTASQFAEDAVDFLKelakKKGKKIKKVAIIYEDSAFGTSV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 183 FATVAAppALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVI--TPTG 260
Cdd:cd06340   161 AKGLKK--AAKKAGLEVVLDEPY---PAGATDLSSEVLKLKAAKPDVVFATSYTNDAILLLRTMKELGFKPKAIigVGGG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 261 WILEPVARAAGDIVVYC----GTSFDPYQDDAHVKAFNAEFKKRVEARLPGQYtlpayydAGAYETVYMFADVLKKSG-L 335
Cdd:cd06340   236 YSDPEFLKALGKDAEGVfsvvPWSPDLAKKKPGAKEVNERYKKKYGEDMTGHA-------ARAYTAAWVLADALERAGsT 308

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1113580614 336 KPDADVQALRSALRDGLQSMkdfpGLGNKITINQEGDAIKPTLIYktngGQW 387
Cdd:cd06340   309 DPEAIRAAAALTLDIPEGLI----MPGGGVKFDEKGQNVLARPVV----VQW 352
PBP1_ABC_HAAT-like cd19988
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-327 1.03e-37

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380643 [Multi-domain]  Cd Length: 302  Bit Score: 137.79  E-value: 1.03e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd19988     1 KIGVFGPLSGDAAPYGQAMLQGAELAVEEINAAGGILGIPIELVVEDDEGLPAASVSAAKKLIyQDKVWAIIGSINSSCT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRN--------SALLQVITDDMvaqvrkdypNAKRVVMVTDPKDAIQk 181
Cdd:cd19988    81 LAAIRVALKAGVPQINPGSSAPTITESGNPWVFRCtpddrqqaYALVDYAFEKL---------KVTKIAVLYVNDDYGR- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 182 fFATVAAPPALTAAGFEIVNKDSYIEipyTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGW 261
Cdd:cd19988   151 -GGIDAFKDAAKKYGIEVVVEESYNR---GDKDFSPQLEKIKDSGAQAIVMWGQYTEGALIAKQARELGLKQPLFGSDGL 226

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1113580614 262 ILEPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEaRLPGQYTlpayydAGAYETVYMFA 327
Cdd:cd19988   227 VTPKFIELAGDAAegAIATTPFLPDSDDPKVSAFVEKYKKRYG-EEPDVFA------AQAYDAMNILA 287
PBP1_ABC_ligand_binding-like cd06345
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-360 1.54e-37

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380568 [Multi-domain]  Cd Length: 356  Bit Score: 138.94  E-value: 1.54e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTgagAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd06345     1 KIGVLGPLS---APAGEAMERGAELAVEEINAAGGILGRKVELVVADTQGKPEDGVAAAERLItEDKVDAIVGGFRSEVV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLA------AENRPYAFR----NSALLQVITDDMVAQVRKDYPNaKRVVMV---TDPK 176
Cdd:cd06345    78 LAAMEVAAEYKVPFIVTGAASPAITkkvkkdYEKYKYVFRvgpnNSYLGATVAEFLKDLLVEKLGF-KKVAILaedAAWG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 177 DAIQKFFATVaappaLTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVI 256
Cdd:cd06345   157 RGIAEALKKL-----LPEAGLEVVGVERF---PTGTTDFTPILSKIKASGADVIVTIFSGPGGILLVKQWAELGVPAPLV 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 257 -------TPTGWilepvaRAAGDIVVYcGTSFDPYQDDAHV----KAFNAEFKKRvearlpgqY-TLPAYYDAGAYETVY 324
Cdd:cd06345   229 ginvpaqDPEFW------ENTGGAGEY-EITLAFAAPKAKVtpktKPFVDAYKKK--------YgEAPNYTAYTAYDAIY 293

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1113580614 325 MFADVLKKSG-LKPDADVQALRSALRDGLQSMKDFPG 360
Cdd:cd06345   294 ILAEAIERAGsTDPDALVKALEKTDYEGVRGRIKFDK 330
PBP1_As_SBP-like cd06330
periplasmic substrate-binding domain of active transport proteins; Periplasmic ...
 31-367 3.34e-37

periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.


Pssm-ID: 380553 [Multi-domain]  Cd Length: 342  Bit Score: 137.69  E-value: 3.34e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNqa 109
Cdd:cd06330     1 KIGVITPLSGAAAVYGEPARNGAELAVEEINAAGGILGRKIELVVRDDKGKPDEAVRAARELVlQEGVDFLIGTISSG-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 rVAFSATN---REKLVSLTPGSNVPGLAAENR-PYAFR--NSALLQVITddMVAQVRKDYPNAKRVVMVTdP-----KDA 178
Cdd:cd06330    79 -VALAVAPvaeELKVLFIATDAATDRLTEENFnPYVFRtsPNTYMDAVA--AALYAAKKPPDVKRWAGIG-PdyeygRDS 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 179 IQKFFATVAAppalTAAGFEIVNKdsyIEIPYTDQDFSVHVTKIKALQPDVVLLSIFydrGVD---FLKEAIRQGL--KT 253
Cdd:cd06330   155 WAAFKAALKK----LKPDVEVVGE---LWPKLGATDYTAYITALLAAKPDGVFSSLW---GGDlvtFVKQAKPYGLfdKT 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 254 PVITPTGWILEpVARAAGD-----IVVYCGTSFDPYQDDAHvKAFNAEFKKRVearlpGQYtlPAYYDAGAYETVYMFAD 328
Cdd:cd06330   225 KVVSGLGGGSE-VLQALGKempegLIGGGRYPFGWPDTPLN-KAFVEAYRAKY-----GEY--PTYWAYEAYAAVMALKA 295

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1113580614 329 VLKKSGlkpDADVQALRSALRdGLQsmkdFPGLGNKITI 367
Cdd:cd06330   296 AIEKAG---STDTDKVIAALE-GLT----FDTPGGKITI 326
PBP1_SBP-like cd19989
periplasmic substrate-binding domain of active transport proteins; Periplasmic ...
 31-327 1.88e-35

periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.


Pssm-ID: 380644 [Multi-domain]  Cd Length: 299  Bit Score: 131.63  E-value: 1.88e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd19989     1 KIGVLTPLSGPYAALGEEARRGAQLAVEEINAAGGILGRPVELVVEDTEGKPATAVQKARKLVeQDGVDFLTGAVSSAVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAEN-RPYAFRnsallqVITDD-----MVAQVRKDYPNAKRVVMVTDPK--DAIQK 181
Cdd:cd19989    81 LAVAPKAAELKVPYLVTVAADDELTGENcNRYTFR------VNTSDrmiarALAPWLAENGGKKWYIVYADYAwgQSSAE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 182 FFATvaappALTAAGFEIVNKdsyIEIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGL--KTPVITPT 259
Cdd:cd19989   155 AFKE-----AIEELGGEVVGT---LFAPLGTTDFSSYITQISDSGADGLLLALAGSDAVNFLKQAGQFGLgkKYKIVGGI 226

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 260 GWILEPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRvearlpgQYTLPAYYDAGAYETVYMFA 327
Cdd:cd19989   227 LSIEPLALPALGDAAegVYGGVRYPPTLDTPANRAFVEAYEKE-------YGEAPDNFAGEAYEAMQALA 289
PBP1_AmiC-like cd06331
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ...
 31-353 5.73e-35

type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.


Pssm-ID: 380554 [Multi-domain]  Cd Length: 333  Bit Score: 131.19  E-value: 5.73e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARA-GVVGIIGPLqTNQA 109
Cdd:cd06331     1 KIGLLTPLSGPASVYGRAIANGAELAVEEINAAGGVLGRPVELVVEDDASDPATAVAAARRLIQQdKVDAIVGPI-TSAT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAF-SATNREKLVSLTPGSNVPGlaaENRPYAFRNSAL-LQVItDDMVAQVRKDYpnAKRVVMVTDpkDAIQKFFATVA 187
Cdd:cd06331    80 RNAVaPVAERAKVPLLYPTFYEGG---ECSPYLFCFGEVpNQQL-DPLIPWLMEEY--GKKFYLIGS--DYVWPRTMNDA 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 188 APPALTAAGFEIVNKDsYieIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGL--KTPVITPT--GWIL 263
Cdd:cd06331   152 ARRVIEAHGGEVVGEE-Y--LPLGTTDFSSVIEKIKASGADVVLSTLVGADAVTFLKQFAAAGLrrKVRIAALLfdENTL 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 264 EPVARAAGDIVVYCGTSFDPYQDDahvkaFNAEFKKRVEARLPGQYTLPAYYDAGAYETVYMFADVLKKSG-LKPDADVQ 342
Cdd:cd06331   229 AGLGAEAAEGIYSVLSYFQSLDTP-----ENKAFVAAYRKKFGEDAPPITSLSEAAYEAVHLYAAAVEKAGsTDPEAVIA 303

                         330
                  ....*....|.
gi 1113580614 343 ALRSALRDGLQ 353
Cdd:cd06331   304 ALPGVSFDGPQ 314
PBP1_ABC_ligand_binding-like cd06336
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ...
 31-348 5.83e-35

type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.


Pssm-ID: 380559 [Multi-domain]  Cd Length: 345  Bit Score: 131.59  E-value: 5.83e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGG--VNG--HPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQ 105
Cdd:cd06336     1 KIGFLGPLSGPAAAWGLPMLRGLELAADEINAAGGikVGGkkYKVEVVSYDDKYTPAEAVAAARRLVsQDGVKFIFGPGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 106 TNQARVAFSATNREKLVSLTPGSNVPGLAAENrPYAFRNSALLQVITDDMVAQVRKDYPnAKRVVMVTdPKDAIQKfFAT 185
Cdd:cd06336    81 SAIAAAVQPVTERNKVLLLTAAFSDPILGPDN-PLLFRIPPTPYEYAPPFIKWLKKNGP-IKTVALIA-PNDATGK-DWA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 186 VAAPPALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFL-KEAIRQGLKTPVITPTGWILE 264
Cdd:cd06336   157 AAFVAAWKAAGGEVVAEEFY---DRGTTDFYPVLTKILALKPDALDLGGSSPGPAGLIiKQARELGFKGPFVSEGGAKAD 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 265 PVARAAG-----DIVVYCGTSFDPYQDDAhVKAFNAEFKKRVearlpGQYtlPAYYDAGAYETVYMFADVLKKSG-LKPD 338
Cdd:cd06336   234 EILKEVGgeaaeGFIGVLPADDDPIASPG-AKAFVERYKKKY-----GEP--PNSESALFYDAAYILVKAMEKAGtVDDT 305

                         330
                  ....*....|
gi 1113580614 339 ADVQALRSAL 348
Cdd:cd06336   306 KKIRAALAML 315
PBP1_ABC_ligand_binding-like cd06338
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ...
 31-387 1.43e-34

type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.


Pssm-ID: 380561 [Multi-domain]  Cd Length: 347  Bit Score: 130.78  E-value: 1.43e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNG----HPIEFVIEDNQTKPELAVSAVRNLARA-GVVGIIGPLQ 105
Cdd:cd06338     1 KIGASLSLTGPFAGEGKAQKRGYELWVEDVNAAGGVKGggkkRPVELVYYDDQSDPATAVRLYEKLITEdKVDLLLGPYS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 106 TNQARVAFSATNREKLVSLTPGSNVPGLAAENRPYAF----RNSALLQVITDDMVAQVrkdyPNAKRVVMVTDpKDAIQK 181
Cdd:cd06338    81 SGLTLAAAPVAEKYGIPMIAGGAASDSIFERGYKYVFgvlpPASDYAKGLLDLLAELG----PKPKTVAIVYE-DDPFGK 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 182 FFATvAAPPALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGW 261
Cdd:cd06338   156 EVAE-GAREAAKKAGLEVVYDESY---PPGTTDFSPLLTKVKAANPDILLVGGYPPDAITLVRQMKELGYNPKAFFLTVG 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 262 ILEPVARAA-GDIV--VYCGTSFDP---YQDDAHVKAFNAEFKKRVEARlpgqytlPAYYDAGAYETVYMFADVLKKSGL 335
Cdd:cd06338   232 PAFPAFREAlGKDAegVLGPSQWEPslpYKVFPGAKEFVKAYKEKFGEE-------PSYHAAAAYAAGQVLQQAIEKAGS 304

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1113580614 336 KPDAdvqALRSALRDGlqsmkDFPGLGNKITINQEGDAI-KPTLIyktngGQW 387
Cdd:cd06338   305 LDPE---KVRDALASL-----DFDTVYGPIKFDETGLQIgKPMVV-----VQW 344
PBP1_ABC_ligand_binding-like cd19984
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-336 1.95e-34

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380639 [Multi-domain]  Cd Length: 296  Bit Score: 128.88  E-value: 1.95e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQTNQA 109
Cdd:cd19984     1 KIGVILPLTGDAASYGEDMKNGIELAVEEINAAGGINGKKIELIYEDSKCDPKKAVSAANKLiNVDKVKAIIGGVCSSET 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENrPYAFRNsallqVITDDMVAQVRKDY---PNAKRVVMVTDP-------KDAI 179
Cdd:cd19984    81 LAIAPIAEQNKVVLISPGASSPEITKAG-DYIFRN-----YPSDAYQGKVLAEFaynKLYKKVAILYENndygvglKDVF 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 180 QKFFatvaappalTAAGFEIVNKDSYIEipyTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPT 259
Cdd:cd19984   155 KKEF---------EELGGKIVASESFEQ---GETDFRTQLTKIKAANPDAIFLPGYPKEGGLILKQAKELGIKAPILGSD 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 260 GWILEPVARAAGDI---VVYCGTSFDPYQDDAHVKAFNAEFKKRVEArlpgqytlPAYYDAGAYETVYMFA-DVLKKSGL 335
Cdd:cd19984   223 GFEDPELLEIAGEAaegVIFTYPAFDDSSEKKQKFFFYRYKEKYGKE--------PDIYAALAYDAVMILAgDVVKPYVI 294


                  .
gi 1113580614 336 K 336
Cdd:cd19984   295 K 295
PBP1_ABC_ligand_binding-like cd06335
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ...
 31-360 3.86e-33

type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.


Pssm-ID: 380558 [Multi-domain]  Cd Length: 348  Bit Score: 126.57  E-value: 3.86e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd06335     1 KIGVIGPLTGPSAELGESARRGVELAVEEINAAGGILGRKIELVERDDEANPTKAVQNAQELIdKEKVVAIIGPTNSGVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGL---AAENRPYAFRNSALLQVITDDMVAQVRKDypNAKRVVMVTDP-------KDAI 179
Cdd:cd06335    81 LATIPILQEAKIPLIIPVATGTAItkpPAKPRNYIFRVAASDTLQADFLVDYAVKK--GFKKIAILHDTtgygqggLKDV 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 180 QKffatvaappALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVllsIFYDRGVDF---LKEAIRQGLKTPVI 256
Cdd:cd06335   159 EA---------ALKKRGITPVATESF---KIGDTDMTPQLLKAKDAGADVI---LVYGLGPDLaqiLKAMEKLGWKVPLV 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 257 TPTGWILEPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKrveaRLPGQYTLPAYYDAGAYETVYMFADVLKKSG 334
Cdd:cd06335   224 GSWGLSMPNFIELAGPLAegTIMTQTFIEDYLTPRAKKFIDAYKK----KYGTDRIPSPVSAAQGYDAVYLLAAAIKQAG 299

                         330       340
                  ....*....|....*....|....*.
gi 1113580614 335 lkpDADvqalRSALRDGLQSMKDFPG 360
Cdd:cd06335   300 ---STD----GKKIRAALENLKGYVG 318
PBP1_ABC_ligand_binding-like cd06346
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-321 8.62e-31

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380569 [Multi-domain]  Cd Length: 314  Bit Score: 119.59  E-value: 8.62e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARA-GVVGIIGPLQTNQA 109
Cdd:cd06346     1 KIGALLPLTGPLASLGPPMLAAAELAVEEINAAGGVLGKKVELVVEDSQTDPTAAVDAARKLVDVeGVPAIVGAASSGVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAA-ENRPYAFRNSAllqviTDDMVAQVRKDYP---NAKRV-VMVTD------PKDA 178
Cdd:cd06346    81 LAVASVAVPNGVVQISPSSTSPALTTlEDKGYVFRTAP-----SDALQGVVLAQLAaerGFKKVaVIYVNndygqgLADA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 179 IQKFFatvaappalTAAGFEIVNKDSYIEipyTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGL-KTPVIT 257
Cdd:cd06346   156 FKKAF---------EALGGTVTASVPYEP---GQTSYRAELAQAAAGGPDALVLIGYPEDGATILREALELGLdFTPWIG 223

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1113580614 258 PTGWILEPVARAAGDIVV--YCGTSfdPYQDD-AHVKAFNAEFKKRVEaRLPGQYTLPAyYDAG-----AYE 321
Cdd:cd06346   224 TDGLKSDDLVEAAGAEALegMLGTA--PGSPGsPAYEAFAAAYKAEYG-DDPGPFAANA-YDAVmllalAYE 291
PBP1_ABC_ligand_binding-like cd19982
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ...
 31-327 1.86e-30

type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.


Pssm-ID: 380637 [Multi-domain]  Cd Length: 302  Bit Score: 118.54  E-value: 1.86e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARA-GVVGIIGPLQTNQA 109
Cdd:cd19982     1 KIGAILSLTGPFAPFGEMFKNGYEMALEEINAAGGIKGKKLELVIEDDQSKPQTALAAAEKLVSQdKVPLIVGGYSSGIT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSAllqviTDDMVAQVRKDY----PNAKRVVMVTDPKDaiqkfFAT 185
Cdd:cd19982    81 LPVAAVAERQKIPLLVPTAADDDITKPGYKYVFRLNP-----PASIYAKALFDFfkelVKPKTIAILYENTA-----FGT 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 186 VAAPPALTAA---GFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTP--VITPTG 260
Cdd:cd19982   151 SVAKAARRFAkkrGIEVVADESY---DKGATDFKPLLNKVKAANPDVVYMVSYLNDAILLMRQAKELGLNPKlfAGGGAG 227

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1113580614 261 WILEPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVearlpGQYtlPAYYDAGAYETVYMFA 327
Cdd:cd19982   228 FTIPEFLKQAGPLAeyVVTATLWSPDVKYPGAKEFYEKYKAKY-----GVE--PSYHEAEAYAALYVAA 289
PBP1_ABC_HAAT-like cd19981
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-300 8.78e-30

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380636 [Multi-domain]  Cd Length: 297  Bit Score: 116.62  E-value: 8.78e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARA-GVVGIIGPLQTNQA 109
Cdd:cd19981     1 KIGFFAPLTGPAAADGKSALHGAELAVEQINAAGGINGKKVELVVYDDQASPKQAVNIAQKLIEQdKVVAVVSGSYSGPT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENrPYAFRNSALLQVITDDMvAQVRKDYPNAKRVVMVTDPKD---AIQKFFATV 186
Cdd:cd19981    81 RAAAPIFQEAKVPMVSAYAVHPDITKAG-DYVFRVAFLGPVQGRAG-AEYAVKDLGAKKVAILTIDNDfgkSLAAGFKEE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 187 AAppaltAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGWILEPV 266
Cdd:cd19981   159 AK-----KLGAEIVSEYAY---ALGDRDFRPILTKIKSANPDAIYASGYYAEAAPIVKQARELGIKVPIIGQEGYDSPKF 230

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1113580614 267 ARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKR 300
Cdd:cd19981   231 IEIAGSAAegVIITTSLNRDSDRPITQKFIKEYRKR 266
PBP1_aromatic_compounds-like cd06332
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ...
 31-381 3.11e-29

type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.


Pssm-ID: 380555 [Multi-domain]  Cd Length: 336  Bit Score: 115.77  E-value: 3.11e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINaaGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd06332     1 KIGLLAPLTGPFAALGEDMVRGFELALEEVG--GEVAGRKVELVVEDDAGDPDTAVTKARKLVeQDKVDVLIGPLSGDEG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENR-PYAFR---NSALLQVITDDMVAQVRKdypnAKRVVMVTD----PKDAIQK 181
Cdd:cd06332    79 LAVAPYAKEPGVPFINPVAGADDLTQRAKaPNFFRtsfTGSQWSAPLGDYAYKELG----YKKVATIGSdyafGYEQAAG 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 182 FFATvaappaLTAAGFEIVNKdsyIEIPYTDQDFSVHVTKIKALQpDVVLLSIFYDRGVDFLKEAIRQGLK--TPVITPT 259
Cdd:cd06332   155 FKRG------FEAAGGEVVQE---IWVPLGTTDFSPYIAQIPSAD-DAVFAFLGGADAVRFLKQYREFGLKdkIPLIGGG 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 260 GWILEPVARAAGDIVV--YCGTSFDPYQDDAHVKAFNAEFKKRVEarlpgqyTLPAYYDAGAYETVYMFADVLKKSGLKP 337
Cdd:cd06332   225 TTVDESVLPAMGDAALgiISASHYAEGLDNPENKKFVAAYKKKFG-------KLPSLYAAGGYDGAQAILEALEAVGGDV 297

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1113580614 338 DaDVQALRSALRdglqsMKDFPGLGNKITINQEGDAIKPTLIYK 381
Cdd:cd06332   298 S-DKQALAAALR-----KVKFDSPRGPFSFDENRNPVQNVYIRE 335
PBP1_ABC_HAAT-like cd06344
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 52-372 8.34e-27

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380567 [Multi-domain]  Cd Length: 332  Bit Score: 109.24  E-value: 8.34e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  52 GAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLAR-AGVVGIIGPLQTNQArVAFSAT-NREKLVSLTPGSN 129
Cdd:cd06344    20 GVELAVEEINAAGGVLGRKIRLVEYDDEASVDKGLAIAQRFADnPDVVAVIGHRSSYVA-IPASIIyERAGLLMLSPGAT 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 130 VPGLAAENRPYAFRNsallqVITDDMVAQVRKDYPNA---KRVVMV-------TDPKDAIQKffatvaappALTAAGFEI 199
Cdd:cd06344    99 APKLTQHGFKYIFRN-----IPSDEDIARQLARYAARqgyKRIVIYydddsygKGLANAFEE---------EARELGITI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 200 VNKDSYieipYTDQ-DFSVHVTKIKAL-QPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGW----ILEPVARAAGDI 273
Cdd:cd06344   165 VDRRSY----SSDEeDFRRLLSKWKALdFFDAIFLAGSMPEGAEFIKQARELGIKVPIIGGDGLdspeLIEIAGKAAEGV 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 274 VVycGTSFDPYQDDAHVKAFNAEFKKRVEaRLPGQYTlpayydAGAYETVYMFADVLKKSG-LKPDADVQALRsalrdgl 352
Cdd:cd06344   241 VV--ATVFDPDDPRPEVRAFVEAFRKKYG-REPDVWA------AQGYDAVKLLAEAIEKAGsTVPAKIASALR------- 304

                         330       340
                  ....*....|....*....|
gi 1113580614 353 qSMKDFPGLGNKITINQEGD 372
Cdd:cd06344   305 -FLENWEGVTGTYSFDANGD 323
PBP1_ABC_HAAT-like cd19983
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-329 7.98e-26

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380638 [Multi-domain]  Cd Length: 303  Bit Score: 105.74  E-value: 7.98e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARAGVVGIIGPLQTNQAR 110
Cdd:cd19983     1 RIGFVGGLTGRYSDLGVQGRNGAQLAVEEINAAGGINGRPVELIIRDDQQDPEAAKAADRELIAGGVVAIIGHMTSAMTV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 111 VAFSATNREKLVSLTPGSNVPGLAAENRpYAFRNSAllqviTDDMVAQVRKDY----PNAKRVVMVTDPKDAI--QKFFA 184
Cdd:cd19983    81 AVLPVINEAKVLMISPTVSTPELSGKDD-YFFRVTP-----TTRESAQALARYaynrGGLRRVAVIYDLSNRAysESWLD 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 185 TVAAppALTAAGFEIVnkdsyIEIPYT---DQDFSVHVTKIKALQPDVVLLsIFYDRGVDFLKEAIR-QGLKTPVITPTG 260
Cdd:cd19983   155 NFRS--EFEALGGRIV-----AEIPFSsgaDVDFSDLARRLLASKPDGLLL-VASAVDTAMLAQQIRkLGSKIPLFSSAW 226

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1113580614 261 WILEPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEARlpgqytlPAYYDAGAYETVYMFA-DV 329
Cdd:cd19983   227 AATEELLELGGKAVegMLFSQAYDRNSSNPRYLAFKEAYEERFGRE-------PSFAAAYAYEAAMVLAgDV 291
PBP1_SBP-like cd20378
periplasmic substrate-binding domain of active transport proteins; Periplasmic ...
 31-353 1.47e-20

periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.


Pssm-ID: 380668 [Multi-domain]  Cd Length: 357  Bit Score: 92.02  E-value: 1.47e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAkdeINAAGGVNGHPIEFVIEDNQTKPELAVSAVRN-LARAGVVGIIGPLQTNQA 109
Cdd:cd20378     1 TLGGLVSMSGAFAAAGKLADRGMRLA---VEEYGGALGRPLKYITRDTEGKPGTGVRKVQEaIAQDGARFFIGGTLSSVA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSALLQVITDDMVAQVRKDYPNAKRVVMVTdPK----DAIQKFFAT 185
Cdd:cd20378    78 LAVSEEAEKAGGVYITSGGADEITGSRCNRSTFRWSVPTYGAIRQTVRPVIKAMPKAKRWYTIT-PQyvfgESLLKNAKE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 186 VAAppaltAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLK--TPVITPTGWIL 263
Cdd:cd20378   157 VLK-----EKGIEHVGNSYH---SLGEREFSGYLTKAMAARPDVLLILNFGSQAVDALRQAVSFGLKrkMKILVAWSSGL 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 264 EPVARAAGDIV--VYCGTSFDPYQDD----AHVKAFNAEFKkrvearlpgqyTLPAYYDAGAYETVYMFADVLKKSGlkp 337
Cdd:cd20378   229 DQFQELGPDICegVYFGAQYWHDVDTpankALVKVYQAKFK-----------ETPSYALAAGYACTRMLLDAIDKAG--- 294

                         330
                  ....*....|....*.
gi 1113580614 338 DADVQALRSALrDGLQ 353
Cdd:cd20378   295 STDPAAVIKAL-EGLK 309
PBP1_ABC_HAAT-like cd19985
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ...
 31-336 4.96e-20

type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.


Pssm-ID: 380640 [Multi-domain]  Cd Length: 321  Bit Score: 89.64  E-value: 4.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARAGVVGIIGPLQTNqar 110
Cdd:cd19985     1 HIAVVGPMSGKSASKGKSMLRGAELYIDQINAAGGINGKKVKLDVFDDQNDPDAARKAAQIIVSDKALAVIGHYYSS--- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 111 VAFSATN---REKLVSLTPGSNVPGLAAENrPYAFRnsallqVITDD-----MVAQVRKDYPNAKRVVMVTDpKDAIQKF 182
Cdd:cd19985    78 ASIAAGKiykKAGIPAITPSATADAVTRDN-PWYFR------VIFNDslqgrFLANYAKKVLKKDKVSIIYE-EDSYGKS 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 183 FATVAApPALTAAGFEIVNKDSY-IEIPYTDQDFSVHVTKIKAL--QPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPT 259
Cdd:cd19985   150 LASVFE-ATARALGLKVLKKWSFdTDSSQLDQNLDQIVDELKKApdEPGVIFLATHADEGAKLIKKLRDAGLKAPIIGPD 228

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1113580614 260 GWilepvaraagdivvycgtsfdpyQDDAHVKAFNAEFKKRVEarlpgqytlPAYYDAGAYETVYMFADVLKKSGLK 336
Cdd:cd19985   229 SL-----------------------ASESFAQGFAEYPEEKEE---------PGYYTDGIYATSPFIFDIANEKAQK 273
PBP1_ABC_ligand_binding-like cd06341
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ...
 31-386 8.27e-20

type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.


Pssm-ID: 380564 [Multi-domain]  Cd Length: 340  Bit Score: 89.29  E-value: 8.27e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLqTNQA 109
Cdd:cd06341     1 KIGLIYPDTGPGAASFSAARAGAEARFGLANAAGGINGRKVEYVWCDDQSDPATNLQAARQLvEDEKVFALVGSS-SAAS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSL-TPGSNVPGLAAENRPYAFRNSALLQVITDDMVAQVrkdypNAKRVVMVTDP-----KDAIQKFF 183
Cdd:cd06341    80 GSANDYLAQAGIPVVgGAGVSVWCFRNMFSNFFSLGGGGSTTTYGQYAAAL-----GGTKAAVVVTDipaasQQLAQQLA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 184 AtvaappALTAAGFEIVnkdSYIEIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGWIL 263
Cdd:cd06341   155 A------SLRAAGVEVV---GTAPYAAAAPDYTAVAQAAKAAGADAVVGVLDPDVAARVLKAARAQGLDLKVALSPSGYD 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 264 EPVARAAGDIV--VYCGTSFDPYQ-DDAHVKAFNAEFKKrvearlpgqY--TLPAYYDAGAYETvYMFADVLKKSGLKPD 338
Cdd:cd06341   226 PSVLAAYGAALagVSVASTFLPFEaDTPAVKAYRAAMAK---------YapELQDPLQQFALSG-YIAADLFVRGLEAAG 295

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1113580614 339 ADVqaLRSALRDGLQSMKDFpglgnkitinqEGDAIKPTLIYKTNGGQ 386
Cdd:cd06341   296 GCP--TRAAFIKALRDVKDY-----------DAGGLLPPGDFTANPGL 330
PBP1_Nba-like cd06359
type 1 periplasmic binding component of active transport systems predicted to be involved in ...
 31-349 5.29e-19

type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.


Pssm-ID: 380582 [Multi-domain]  Cd Length: 333  Bit Score: 86.92  E-value: 5.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINaaGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd06359     1 KIGFITTLSGPAAVLGQDMRDGFNLALEQLG--GKLGGLPVEVVVEDDQLKPDVAKQAAERLIeRDKVDFVTGIIFSNVM 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAEN-RPYAFRNSALlqvitDDMVAQVRKDYPNAKRV--VMVTDP-----KDAIQK 181
Cdd:cd06359    79 LAVVKPVVDSKVFYISANAGPSDLAGKGcNPNFFVTSWQ-----NDQLHEAAGKYANDKGYkrVYLLAPnyqagKDALAG 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 182 FfatvaappALTAAGfEIVNKDSyieIPYTDQDFSVHVTKIKALQPDVVLlsIFY--DRGVDFLKEAIRQGLKT--PVIT 257
Cdd:cd06359   154 F--------KRTYKG-EVVGEIY---TPLGQLDFSAELAQIRAAKPDAVF--AFYpgGMGVNFVKQYAQAGLKKkiPLYT 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 258 PtGWIL-EPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVeARLPGQYTlpayydAGAYETVYMFADVLKKSG 334
Cdd:cd06359   220 V-GTLDdEDLLPAMGDAAlgVLSVSQWSPDLDNPENKRFVAAFRKKY-GRPPSNYA------AQGYDAALLIDAAVKAVG 291

                         330
                  ....*....|....*
gi 1113580614 335 lKPDADVQALRSALR 349
Cdd:cd06359   292 -GDLSDKDALRAALR 305
ANF_receptor pfam01094
Receptor family ligand binding region; This family includes extracellular ligand binding ...
 48-384 6.96e-19

Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.


Pssm-ID: 460062 [Multi-domain]  Cd Length: 347  Bit Score: 87.06  E-value: 6.96e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  48 HMQIGAEIAKDEINAAGGVN-GHPIEFVIEDNQTKPELAVSAVRNLARAGVVGIIGPLQTNQARVAFSATNREKLVSLTP 126
Cdd:pfam01094   1 LVLLAVRLAVEDINADPGLLpGTKLEYIILDTCCDPSLALAAALDLLKGEVVAIIGPSCSSVASAVASLANEWKVPLISY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 127 GSNVPGLAAENR-PYAFRNSALLQVITDDMVAQVRkdYPNAKRVVMVTDPKD----AIQKFFAtvaappALTAAGFEIVN 201
Cdd:pfam01094  81 GSTSPALSDLNRyPTFLRTTPSDTSQADAIVDILK--HFGWKRVALIYSDDDygesGLQALED------ALRERGIRVAY 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 202 KDSYIEIPYTDQDFSVhVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTP--VITPTGW------ILEPVARAAGDI 273
Cdd:pfam01094 153 KAVIPPAQDDDEIARK-LLKEVKSRARVIVVCCSSETARRLLKAARELGMMGEgyVWIATDGlttslvILNPSTLEAAGG 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 274 VVYCgTSFDPyqDDAHVKAFnAEFKKRVEARLPGQYT-LPAYYDAGAYETVYMFADVLKKSGLKPDADVQALRSALRDGL 352
Cdd:pfam01094 232 VLGF-RLHPP--DSPEFSEF-FWEKLSDEKELYENLGgLPVSYGALAYDAVYLLAHALHNLLRDDKPGRACGALGPWNGG 307

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1113580614 353 QSMKD------FPGLGNKITINQEGDAIKPTL-IYKTNG 384
Cdd:pfam01094 308 QKLLRylknvnFTGLTGNVQFDENGDRINPDYdILNLNG 346
PBP1_SBP-like cd06329
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ...
 31-350 2.97e-18

periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.


Pssm-ID: 380552 [Multi-domain]  Cd Length: 343  Bit Score: 85.02  E-value: 2.97e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARAGvVGIIgpLQTNQAR 110
Cdd:cd06329     1 KIAFIDPLSGPFASVGEIYLKGLQFAIEEINAGGGLLGRKIELVPFDNKGSPQEALIQLKKAIDQG-IRFV--LQGNSSA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 111 VAFSAT-----------NREKLVsLTPGSNVPGLAAEN-RPYAFRNSALLQVITDDMVAQVRKDyPNAKRVVMVT----- 173
Cdd:cd06329    78 VAGALIdaiekhnqrnpDKRVLF-LNYGAEAPELTGAKcSFWHFRFDANADMKMAALADYMKKD-GSIKKVYLINqdysf 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 174 --DPKDAIQKFFATvAAPpaltaaGFEIVNKDsYIEIpYTDQDFSVHVTKIKALQPDVVllsIFYDRGVD---FLKEAIR 248
Cdd:cd06329   156 grDVAAAAKKNLKK-KRP------DIEIVGED-LHPL-GKVKDFSPYIAKIKASGADTV---ITGNWGNDltlLMKAARD 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 249 QGLKTPVIT--------PTgwilepVARAAGDIVVYCGTSFDPYQDDAHVKAFNAEFKKRvearlpgQYTLPAYYDAGAY 320
Cdd:cd06329   224 SGLKAPFYTyyadgpgaPA------AIGEAGVGRLVAVAYWHPNPKTPELEKFAEAFRAK-------YGRYPDFNIGRTY 290

                         330       340       350
                  ....*....|....*....|....*....|
gi 1113580614 321 ETVYMFADVLKKSGlkpDADVQALRSALRD 350
Cdd:cd06329   291 MGVEMLAAAIKKAG---STDPEKVAKALEG 317
PBP1_ABC_ligand_binding-like cd19978
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ...
 30-370 6.19e-18

periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.


Pssm-ID: 380633 [Multi-domain]  Cd Length: 341  Bit Score: 84.16  E-value: 6.19e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  30 YKIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARA-GVVGIIGPLQTNQ 108
Cdd:cd19978     1 IRLGMSAALSGPAAELGNEMKRGIEAAFNEVNAQGGVNGRKIKLIALDDGYEPDRTVKNTKKLIEEdKVFALIGYVGTPT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 109 ARVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSALLQVITDDMVAQVRKDYPnAKRVVMV-------TDPKDAIQK 181
Cdd:cd19978    81 ALAALPLANEKKIPLFGPFTGAEFLRTPFLPYVFNLRASYADETEALVDYLVKTLG-PKRIAIFyqndafgLAGLEGAKK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 182 ffatvaappALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVIT---- 257
Cdd:cd19978   160 ---------ALKKRGLTPVAEGSY---TRNTLDVEEALAKILKAKPEAIILVGTYAPAAEFIRLARAAGLNPLFANvsfv 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 258 -PTGWILEPVARAAGDIVvycgTSFDPYQDDAH---VKAFNAEFKKRVEARLPGQYTLPAYYDAgayetvYMFADVLKKS 333
Cdd:cd19978   228 gSEALALELGDYGEGVIV----SQVVPDPNDSSlpiVKEYREAMKKYGPNAPPDFVSLEGYLAA------RLLVEALKKA 297

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1113580614 334 GLKPDadvqalRSALRDGLQSMKDFPGLGNKITINQE 370
Cdd:cd19978   298 GPPLT------REKLLALEESLKNDLGKGLTLTFSPN 328
PBP1_ABC_ligand_binding-like cd06334
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ...
 31-387 1.98e-17

type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.


Pssm-ID: 380557 [Multi-domain]  Cd Length: 360  Bit Score: 82.68  E-value: 1.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAV-RNLARAGVVGIIGpLQT--N 107
Cdd:cd06334     1 KIGLLTDLTGPTADVGKPYAQGVRDYLNYVNEEGGINGVKIELEECDTGYKVPRAVACYkRLKAQDGVVAILG-WGTgdT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 108 QARVAFSATNREKLVSltpGSNVPGLAA--ENRPYAF--------RNSALLQVItddmvAQVRKDYPNAKRVVMV----- 172
Cdd:cd06334    80 EALAPRVAKDKIPYIS---ASYGRSLADdgKVFPYNFfvgatyssQARALLKYI-----AQEWGGKLKGPKVAFVyhdsp 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 173 --TDPKDAIQKFfatvAAppaltAAGFEIVNkdsYIEIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQG 250
Cdd:cd06334   152 fgREPIPALKAY----AK-----ELGFEVVA---EQVPSPGALDATAQWLRIRRAGPDYVIIQGTGGSVAVIIKDAKRLG 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 251 LKTPVITpTGWIL-EPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEARLPGQYtLPAYYDAGAYeTVYMFA 327
Cdd:cd06334   220 LKTKFIG-NIWGGdEDLIKLAGDAAegYVGVSPFAFGTDDPPGKEIVEEVAKKGKGDGPEEV-GTVYYNRGWA-TAMLAV 296

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1113580614 328 D----VLKKSGLKPdadvqaLRSALRDGLQSMKDF--PGLGNKITI---NQEGdaIKPTLIYKTNGGQW 387
Cdd:cd06334   297 EairrADKAGGGTG------LGNKLKAGLERLKDFdlGGLAPPVTFtptDHRG--GGVVRIYQWDGGKW 357
PBP1_SBP-like cd19987
periplasmic substrate-binding domain of active transport proteins; Periplasmic ...
 31-345 3.30e-17

periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.


Pssm-ID: 380642 [Multi-domain]  Cd Length: 353  Bit Score: 81.99  E-value: 3.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAG------------GVNGHPIEFVIEDNQTKPELAV-SAVRNLARAGV 97
Cdd:cd19987     1 TIGLNVPLSGPYAPQGEDQRRGFELAVDHLNNGGglvdkdsrlsgdGILGKKVELVTADTETKADTAVdNAKRLIEQDGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  98 VGIIGPLQTNQARVAFSATNREKLV---SLTPGSNVPGlaAENRPYAFRNSALLQVITDDMVAQVRKDYPNAKRVVMVT- 173
Cdd:cd19987    81 VMITGGSSSAVAVAAQKLAQKEGVLyfaGLSHSNDTTG--KDCHRYGFRECFNAHMSAKALAPYLVEKFGKDRKYFYLTa 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 174 ------DPKDAIQKFfatvaappaLTAAGFEIVNKDSyieIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAI 247
Cdd:cd19987   159 dytwghSTEQSMREY---------TEAHGWKTVGNPA---TPLGETDFSAALLNAADSGADVLVLVLFGRDMVNALKQAK 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 248 RQGL--KTPVITP--TGWILEPVaraAGDIV--VYCGTSFDPYQDDAH--VKAFNAEFKKRvEARLPGQytlPAyydAGA 319
Cdd:cd19987   227 QFGLlkKMDIVVPllTAFMAESV---GPEIMegVLGTVNWHWSLPDDYsyAFGKAEAFEKE-YGAYPSQ---AA---ASA 296

                         330       340
                  ....*....|....*....|....*..
gi 1113580614 320 YETVYMFADVLKKSG-LKPDADVQALR 345
Cdd:cd19987   297 YVQVLQYAAAVERAGsFDPPAVIRALE 323
PBP1_alkylbenzenes-like cd06360
type 1 periplasmic binding component of active transport systems predicted be involved in ...
 31-390 1.12e-16

type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.


Pssm-ID: 380583 [Multi-domain]  Cd Length: 357  Bit Score: 80.42  E-value: 1.12e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEInaAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQA 109
Cdd:cd06360     1 KIGVLLPLTGPLAVNGEDVRDGFELYFDEI--GNQVAGRKIELIVEDDEGKPDVGLTKARKLVeRDKVHVLAGIVSSAVA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENR-PYAFRNSallqvitddmVAQVRKDYP---------NAKRVVMVTdpKDAI 179
Cdd:cd06360    79 YAVRDYVVEQKIPLVISNAGAAPLTQELAsPYIFRTS----------FSNGQYDAPfgqyayeklGYRRIAVMA--SDYA 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 180 QKFFATVAAPPALTAAGFEIVNKdsyIEIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLK--TPVIT 257
Cdd:cd06360   147 AGHEQAGAFARTFKQAGGKVVQE---IYPPLGTADFAPYLARIQQDAADAVWAFFAGADAIRFVKQYDEYGLKgkLPLVG 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 258 PTGWILEPVARAAGD--IVVYCGTSFDPYQDDAHVKAFNAEFKKRVEaRLPGqytlpaYYDAGAYETVYMFADVLKKSGL 335
Cdd:cd06360   224 IGGLVDDAILPEQGDaaLGIVSYLHYSAALDTPENKAFVQAYRKKYG-RDPG------LYAEGGYVAARAIAEALEAVKG 296

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1113580614 336 KPdADVQALRSALRDglqsmKDFPGLGNKITINQEGDAIKPTLIYKT--NGGQWARA 390
Cdd:cd06360   297 NV-EDKEAFLEALRK-----VRFEAPRGPFRFDPYQQAVVTTYIRRVekVDGKLVNV 347
PBP1_ABC_ligand_binding-like cd06326
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ...
 32-358 1.79e-16

periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.


Pssm-ID: 380549 [Multi-domain]  Cd Length: 339  Bit Score: 79.51  E-value: 1.79e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  32 IGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLQTNQAR 110
Cdd:cd06326     3 IGQSAPLSGPLAELGREYLAGAKAYFDQVNAAGGINGRKIRLVTLDDGYDPARTVENTRQLIeQDKVVALFGYVGTANVE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 111 VAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSALLQVITDDMVAQVRKdyPNAKRVVMVTDPKDAIQKFFATVAApp 190
Cdd:cd06326    83 AVLPLLEEAGVPLVGPLTGADSLREPGNPYVFHVRASYADEVEKIVRHLAT--LGLKRIAVVYQDDPFGKEGLAAAEA-- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 191 ALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVITPTGWILEPVARAA 270
Cdd:cd06326   159 ALAARGLEPVATAAV---ARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFIKALRAAGGAAQFYGLSVVGAAALAKAL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 271 GDIVVycGTSF-----DPYQD-DAHVKAFNAEFKKRVEARlPGQYTLPAYYDAGAyetvymFADVLKKSGLKPDadvqal 344
Cdd:cd06326   236 GDAAR--GVVVsqvvpNPWSTtLPLVREYQAAMKAAGPKE-PSYASLEGYIAARV------LVEALRRAGRNPT------ 300

                         330
                  ....*....|....
gi 1113580614 345 RSALRDGLQSMKDF 358
Cdd:cd06326   301 RESLVAALESLGRL 314
PRK15404 PRK15404
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
19-343 2.22e-16

high-affinity branched-chain amino acid ABC transporter substrate-binding protein;


Pssm-ID: 237959 [Multi-domain]  Cd Length: 369  Bit Score: 79.68  E-value: 2.22e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  19 SLGGAAIAQQpYKIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARAGVV 98
Cdd:PRK15404   16 ALSHAALADD-IKIAIVGPMSGPVAQYGDMEFTGARQAIEDINAKGGIKGDKLEGVEYDDACDPKQAVAVANKVVNDGIK 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  99 GIIGPLQTNQARVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSALlqvitDDM----VAQVRKDYPNAKRVVMVTD 174
Cdd:PRK15404   95 YVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLIFRTIGL-----DSDqgptAAKYILEKVKPKRIAVLHD 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 175 PKDAIQKFFATVAAppALTAAGFEIVNKDSyieIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTP 254
Cdd:PRK15404  170 KQQYGEGLARSVKD--GLKKAGANVVFFEG---ITAGDKDFSALIAKLKKENVDFVYYGGYHPEMGQILRQAREAGLKTQ 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 255 VITPTGWILEPVARAAGD----IVVYCGTSFDpyQDDAH---VKAFNAefKKRVEArlpGQYTLPayydagAYETVYMFA 327
Cdd:PRK15404  245 FMGPEGVGNKSLSNIAGPasegMLVTLPKRYD--QDPANkaiVDAFKA--KKQDPS---GPFVWT------TYAAVQSLA 311

                         330
                  ....*....|....*.
gi 1113580614 328 DVLKKSGLKPDADVQA 343
Cdd:PRK15404  312 AGINRAGSDDPAKVAK 327
PBP1_NHase cd06358
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively ...
 31-352 2.69e-14

type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides; This group includes the type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides, which are subsequently converted by amidases to yield free carboxylic acids and ammonia. NHases from bacteria and fungi have been purified and characterized. In Rhodococcus sp., the nitrile hydratase operon consists of six genes encoding NHase regulator 2, NHase regulator 1, amidase, NHase alpha subunit, NHase beta subunit, and NHase activator. The operon produces a constitutive hydratase that has a broad substrate spectrum: aliphatic and aromatic nitriles, mononitriles and dinitriles, hydroxynitriles and amino-nitriles, and a constitutive amidase of equally low substrate specificity. NHases are metalloenzymes containing either cobalt or iron, and therefore can be classified into two subgroups: ferric NHases and cobalt NHases.


Pssm-ID: 380581 [Multi-domain]  Cd Length: 333  Bit Score: 73.01  E-value: 2.69e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARAGVV-GIIGpLQTNQA 109
Cdd:cd06358     1 RIGLLIPLSGPAGLWGPSCEACAELAAAEINAAGGILGREVELVLIDAGGPPAEVAAAARRLVDDGAVdAIVG-MHTSAV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAfsatnrekLVSLTPGSnVPGLAA------ENRPYAF----RNSALLQVITDDMVAQVRkdypnAKRVVMVTDpkDAI 179
Cdd:cd06358    80 RQA--------LANAVGGR-VPYVYTplyeggERTPGVYaigeTPEEQLRPALRWLADERR-----VRRWFLVGN--DYV 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 180 --QKFFATVAAppALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKTPVIT 257
Cdd:cd06358   144 wpRASHAAARR--YIARLGGEVVGERFV---PLGEDDFERVLARIRASRPDAVLISLVGQDAVDFNRAFAAAGLAGRILR 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 258 PTGWILEPV-----ARAAGDIvvYCGTS-FDPYQDDAhvkafNAEFKKRVEARLPGQYTLPAYYDAGAYETVYMFADVLK 331
Cdd:cd06358   219 LSPAIDENVllaigADATENL--YSASGyFASLRTAA-----NLAFLERYHAAFGDRAPPLNALGESCYEGVHFLAALAR 291

                         330       340
                  ....*....|....*....|.
gi 1113580614 332 KSGlkpDADVQALRSALRDGL 352
Cdd:cd06358   292 RAG---SLDVRALAAAAEGLT 309
PBP1_RPA0668_benzoate-like cd20014
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ...
 31-351 5.55e-14

type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).


Pssm-ID: 380667 [Multi-domain]  Cd Length: 346  Bit Score: 72.27  E-value: 5.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINaaGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPLQTNQA 109
Cdd:cd20014     1 KIGLLLPYSGVYAALGEDIRNGFQLYLDEHG--GKLGGRPIELVKEDDEADPDVALQKARKLiEQDKVDVLVGPVSSGVA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENR-PYAFRNSALLQVITDDMVAQVRKDYpnAKRVVMVTDP----KDAIQKFFA 184
Cdd:cd20014    79 LAIRDVVEQAKVPLIVANAGANALTRAACsPYIFRTSFSNWQLGYALGKYAAENV--GKTVVTIASDyaagREVVAGFKE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 185 tvaappALTAAGFEIVNKDSyiEIPYTDQDFSVHVTKIKALQPDVVLlsIFY--DRGVDFLKEAIRQGL--KTPVITPtG 260
Cdd:cd20014   157 ------GFEAAGGKVVGEIW--TPLGTTTDFSPYLTQIAASGPDAVY--AFFagADAVRFVKQYAEFGLkgKIPLYGP-G 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 261 WIL-EPVARAAGDIV--VYCGTSFDPYQDDAHVKAFNAEFKKRVEaRLPGQYTLPAyYDAGAyetvyMFADVLKKSGLKP 337
Cdd:cd20014   226 FLTdEDVLPALGEAAegIITVLHYAPTLDNPANRAFVAAYQAKYG-RLPDVYAVQG-YDAAQ-----VIDAALEAVGGDT 298

                         330
                  ....*....|....
gi 1113580614 338 DaDVQALRSALRDG 351
Cdd:cd20014   299 S-DKDILAAALELG 311
PBP1_ABC_ligand_binding-like cd19979
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ...
 31-352 2.70e-13

amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.


Pssm-ID: 380634 [Multi-domain]  Cd Length: 350  Bit Score: 70.33  E-value: 2.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIG-----PL 104
Cdd:cd19979     1 VIGLDADLSGGSAASGEAIKRGIQLAIDEINAAGGLLGRKLELVAKDHRGNPARGVDNLREFAaDPDVLAVFGglhspVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 105 QTNQARVafsatNREKLVSLTP-GSNVPGLAAENRP-YAFRNSAllqvitDD------MVAQVRKDYpnAKRVVMV---T 173
Cdd:cd19979    81 LAELDFI-----HELKIPYLVPwAAATPITRNGYSPnYIFRLSV------DDslagpfLVEYALKKG--CKRPALLlenT 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 174 DPKDAIQKffatvAAPPALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLKT 253
Cdd:cd19979   148 GWGRSNLK-----AMTKALAKKGLQPVGVEWF---NWGDTDAKPQLRALKAAGADAILLVANAPEGAAIVKALAALPERL 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 254 PVIT---PTG---WILEPVARAAGDIVVYCGTSFDPYQDDAHVKAFnAEFKKRVEARLPGQYTLPAyyDAG---AYETVY 324
Cdd:cd19979   220 PIIShwgITGgdfPELPREALSKIDLRFIQTFSFFDANQSPRGKQV-LARYKRRYPVEDPESDIPA--PVGfahAYDLTH 296

                         330       340       350
                  ....*....|....*....|....*....|
gi 1113580614 325 MFADVLKKSGLKPDADVQALRSALR--DGL 352
Cdd:cd19979   297 LLALAIEQAGSTDRAAVRAALELLPphEGL 326
PBP1_AmiC cd06357
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ...
 31-350 2.50e-12

periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.


Pssm-ID: 380580 [Multi-domain]  Cd Length: 357  Bit Score: 67.60  E-value: 2.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGpLQTNQA 109
Cdd:cd06357     1 RVGLLFSQTGVTAIIEQSMLNGALLAIEEINAAGGVNGRPIEPVVYDPASDPDRYRELAERLlLEDGVRHIFG-CYTSAS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVA------------FSATNREklvsltpgsnvpGL-AAENRPY--AFRNSALLQVItDDMVAQVRKdypnakRVVMV-T 173
Cdd:cd06357    80 RKAvlpvverhnallWYPTPYE------------GFeYSPNVIYtgAVPNQHLLPLA-RYLLAHFGK------RVFLVgS 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 174 D---PK--DAIQKFFatvaappaLTAAGFEIVNkDSYIeiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIR 248
Cdd:cd06357   141 NyvyPWesNRVAREL--------IEASGGEVVG-ERYV--PLGDTDFAEIIEEIKSLKPDVVFSTLVGDSIYAFYRAYAE 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 249 QGL---KTPVITPTgwILEP------VARAAGDIVvyCGTSFDPYQDDAhvkafNAEFKKRVEARLPGQYTLPAYYDAgA 319
Cdd:cd06357   210 AGLdpaDMPIASLT--TSEAevaaigAEAAAGHYT--SAPYFQSIDTPE-----NRAFVEAYRARFGDDAVTSAVAEA-A 279

                         330       340       350
                  ....*....|....*....|....*....|.
gi 1113580614 320 YETVYMFADVLKKSGlkpDADVQALRSALRD 350
Cdd:cd06357   280 YFQVHLLARAIERAG---SDDPEAIRAALYG 307
PBP1_RPA0985_benzoate-like cd20013
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the ...
 31-340 2.79e-10

type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0985 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0985 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).


Pssm-ID: 380666 [Multi-domain]  Cd Length: 356  Bit Score: 61.12  E-value: 2.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEinAAGGVNGHPIEFVIEDNQ-TKPELAVSAVRNL-ARAGVVGIIGPLQTNQ 108
Cdd:cd20013     1 KVGVIGPFSGPFADYGKQFDRGIDLYLKL--HGDKVGGRKVEVIYRDDGgPNPAVAKRLAQELiVRDKVQILIGFGFTPN 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 109 ARVAFSATNREKLVSLTPGSNVPGLAaENRPYAFRNSALLQVITDDMVAQVRKDypNAKRV-VMVTD--P-KDAIQKFfa 184
Cdd:cd20013    79 ALAVAPVATEAKTPTVIMNAATSSIT-RKSPYFVRTSFTMWQVAYPMGKWAAKN--GIKKAyTAVADyaPgHDAETAF-- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 185 tvaaPPALTAAGFEIVNKdsyIEIPYTDQDFSVHVTKIKALQPDVVLlsIFY---DRGVDFLKEAIRQGLKTP---VITP 258
Cdd:cd20013   154 ----KKAFEAAGGKIVGS---IRVPLATPDFAPFMQRIKDAKPDAVF--VFVpagAPSIGFLKAYAERGLKEAgikLLGT 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 259 TGWILEPVARAAGDIVV--YCGTSFDPYQDDAHVKAFNAEFKKRVearlpGQYTLPAYYDAGAYETVYMFADVLKKSGLK 336
Cdd:cd20013   225 GDATDDDDLPAMGDAALglITAGHYSAALDSPENKAFVAAYQKAY-----GPDARPDFMAVAAYDGMALIYKMIKATGGK 299


                  ....
gi 1113580614 337 PDAD 340
Cdd:cd20013   300 FDGD 303
PBP1_SBP-like cd06328
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ...
 31-348 3.46e-09

periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.


Pssm-ID: 380551 [Multi-domain]  Cd Length: 336  Bit Score: 57.69  E-value: 3.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEinAAGG---VNGHPIEFVIEDNQTKPELAVSAVRNL-ARAGVVGIIGPL-Q 105
Cdd:cd06328     1 KIGVITSLTGPLAAYGKQTERGFELGLEY--ATDGtmeVDGRKIEVIVKDDQGDPDTAKAAATELiGDDGVDILVGTVsS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 106 TNQARVAFSATNREKLVSLTPGSnVPGLAAEN-RPYAFRNS--------ALLQVITDDM---VAQVRKDYPNAKrvvmvt 173
Cdd:cd06328    79 AVALALAPVAEQNKKILIVGPAA-ADSITGENwNKYTFRTSrnswqdaiAGAKALADPLgksVAFLAQDYAFGQ------ 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 174 dpkdaiqkffATVAA-PPALTAAGFEIVNKdsyIEIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGL- 251
Cdd:cd06328   152 ----------DGVAAfKKALEAKGGKIVGE---ELVPVTTTDFTPYLQRILDAKPDVLFVAWAGTGALTLWQQLADQGVl 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 252 -KTPVITPTGWIlEPVARAAGDIVVYCGTSFDPYQ------DDAHVKAFNAEFKkrvearlpgqyTLPAYYDAGAYETVY 324
Cdd:cd06328   219 dDIKVVTGGPDI-ATLAALGDALPGIEGLTYYYYGlpknpvNDWLVKAHKERYN-----------APPDLFTAGGFAAAQ 286

                         330       340
                  ....*....|....*....|....
gi 1113580614 325 MFADVLKKSGlkPDADVQALRSAL 348
Cdd:cd06328   287 AVVRALEKAG--GDTDVEKLIAAL 308
PBP1_ABC_ligand_binding-like cd06337
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ...
 31-350 3.94e-09

type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.


Pssm-ID: 380560 [Multi-domain]  Cd Length: 354  Bit Score: 57.70  E-value: 3.94e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFG---PHMqigAEIAKDEINAAGGVNG---HPIEFVIEDNQTKPELAVSAVRNL-ARAGV---VGI 100
Cdd:cd06337     1 KIGRVSPLTGPLAAFGeadPWV---LEQIREAFADGGIKVGgkkYPVEIVVRDSQSDPNRAGEAARDLiLRDKVdlmLAS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 101 IGPLQTNqARVAFSATNREKLVSltpgSNVP------GL-AAENRPyaFRNSALLQVITDDMVAQVRKDYPNAK--RVVM 171
Cdd:cd06337    78 GTPDTVN-PVADQCEANGVPCIS----TDAPwqawffGRgGDPAKG--FKWTFHFFWGLEDIAANFLGMWDQVPtnKVVG 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 172 VTDPKDAIQKFFATvAAPPALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGL 251
Cdd:cd06337   151 LLWPNDPDGTAFAD-AFLGLPAAAGYTLVDPGRF---PPGTDDFSSIINAFKKAGVEIVTGVMIPPDFATFWRQAAQQGF 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 252 KTPVITPTGWILEP-VARAAGD------IVVYCGTSFdPYQD-----DAhvkafnAEFKKRVEARLPGQYTLPAYYDAGA 319
Cdd:cd06337   227 KPKVVTIGKALLFPsAVAALGDlgdglsTEVWWSPAH-PFKSsltgqTA------AELADAYEKATGKQWTQPLGYAHAL 299

                         330       340       350
                  ....*....|....*....|....*....|.
gi 1113580614 320 YETVymfADVLKKSGlkpDADVQALRSALRD 350
Cdd:cd06337   300 FEVA---VDALKRAG---SPDDEAVRAALAD 324
PBP1_FmdD-like cd06355
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ...
 56-367 4.21e-09

periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.


Pssm-ID: 380578 [Multi-domain]  Cd Length: 347  Bit Score: 57.59  E-value: 4.21e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  56 AKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLARA-GVVGIIGpLQTNQARVA----FSATNR--------EKL- 121
Cdd:cd06355    26 AIDEINAAGGLLGRKIEPVIEDGASDWPTFAEKAEKLITQdKVAVIFG-CWTSASRKAvlpvIEKYNGllfypvqyEGLe 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 122 -------VSLTPGSNV-PGLAaenrpYAFRNsallqvitddmvaqvrkdypNAKRVVMV-TD---PKDA---IQKFfatv 186
Cdd:cd06355   105 qspnivyTGATPNQQIlPAID-----WLLEN--------------------LGKRFFLVgSDyvfPRTAnkiIRDQ---- 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 187 aappaLTAAGFEIVNKDsYIeiPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGLK---TPVITPTgwIL 263
Cdd:cd06355   156 -----LKALGGEVVGEE-YV--PLGGTDFDAIVAKIKAFKPDVIVNTLNGDSNIAFFKQLAAAGITasdLPVLSFS--VS 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 264 EPVARAAGDIVV---YCGTSFDPYQDDAHVKAFNAEFKKRVEARLPgqYTLPAyydAGAYETVYMFADVLKKSGlkpDAD 340
Cdd:cd06355   226 EAELRAIGPEELaghYAAWNYFQSLDTPENQAFVEAFKAKYGADRV--TSDPM---EAAYLGVYLWAQAVEKAG---SFD 297

                         330       340
                  ....*....|....*....|....*..
gi 1113580614 341 VQALRSALRDglQSmkdFPGLGNKITI 367
Cdd:cd06355   298 PDAVRAALKG--QS---FEAPGGTVTV 319
PBP1_amide_urea_BP-like cd06356
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ...
 31-349 1.65e-08

periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the type 1 periplasmic-binding proteins that are predicted to have a function similar to that of an active transport system for short chain amides and/or urea in bacteria and Archaea, by sequence comparison and phylogenetic analysis.


Pssm-ID: 380579 [Multi-domain]  Cd Length: 334  Bit Score: 55.77  E-value: 1.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPELAVSAVRNLA-RAGVVGIIGPLqTNQA 109
Cdd:cd06356     1 KIGSIFDLSGGLNIYGKPMVHAMKLAVEEINAAGGLLGRQIELVAYDTQSDMQKYTQYAQQLIlRDKVDVVFGGI-TSAS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVAFSATNREKLVSLTPGSNVPGLAAENRPYAFRNSALLQVIT--DDMVAQVRK-------DYpNAKRVVmvtdpKDAIQ 180
Cdd:cd06356    80 REAIRPILRRNKILYFYNTQYEGGVCDKNTFCTGSTPEQQVSPliEWAIKKYGKkvyiiaaDY-NFGQIS-----ADWVK 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 181 KFfatvaappaLTAAGFEIVNKDSyieIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGL--KTPVITP 258
Cdd:cd06356   154 KY---------AKKNGGEVVGEEF---FPLDVTDFGPTIQKIQAAKPDFVVSLLVGGNHISFYRQWAAAGLkkKIPIVST 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 259 T--GW----ILEPVArAAGDIVVYcgtsfdPYQDDAHVKAfNAEFKKRVEARLP--GQYTLPAyydAGAYETVYMFADVL 330
Cdd:cd06356   222 VfgAGnehkVLSPPE-LEGMYVSY------SYFEELDTPA-NKAFVAKWRAKYGdePYINQEA---VGVYNAVYLWAEAV 290

                         330       340
                  ....*....|....*....|
gi 1113580614 331 KKSG-LKPDADVQALRSALR 349
Cdd:cd06356   291 EKAGsTEREAVIAALESGIS 310
PBP1_YraM_LppC_lipoprotein-like cd06339
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ...
 31-145 1.42e-06

periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).


Pssm-ID: 380562 [Multi-domain]  Cd Length: 331  Bit Score: 49.58  E-value: 1.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEinaaggVNGHPIEFVIEDNQtKPELAVSAVRNLARAGVVGIIGPLQTNQAR 110
Cdd:cd06339     1 RIALLLPLSGPYAAAGQAIRDGIELALFD------AGGSRPELRVYDTG-GPEGAAAAYQQAVAEGADLIIGPLLKSSVA 73

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1113580614 111 VAFSATNREKLVSLTPgSNVPGLAAenRPYAFRNS 145
Cdd:cd06339    74 ALAAAAQALGVPVLAL-NNDESATA--GPGLFQFG 105
Peripla_BP_5 pfam13433
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ...
 31-350 4.75e-06

Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins.


Pssm-ID: 463875 [Multi-domain]  Cd Length: 363  Bit Score: 47.97  E-value: 4.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGFGPHMQIGAEIAKDEINAAGGVNGHPIEFVIEDNQTKPEL-AVSAVRNLARAGVVGIIGpLQTNQA 109
Cdd:pfam13433   2 KVGVLHSLTGTMAISERSLKDATLMAIEEINAAGGVLGRKIEPVVVDPASDWPLfAEKARKLIDQDKVRVVFG-CWTSAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 110 RVA------------FSATNREKLVSltpGSNV--PGlAAENRpyafrnsallQVItdDMVAQVRKDYPnaKRVVMV-TD 174
Cdd:pfam13433  81 RKAvlpvferhngllFYPVQYEGFES---SRNIfyTG-AAPNQ----------QAI--PAVDYLLSELG--KRFFLVgSD 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 175 ---PKDAIQKFFAtvaappALTAAGFEIVNkDSYieIPYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGL 251
Cdd:pfam13433 143 yvyPRTTNRILRA------YLKAKGGEVVG-ERY--LPLGSSDWQSIVAKIKAAGPDVVFSTINGDSNVAFYRALRAAGI 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 252 ---KTPVITPTgwILEP------VARAAGDIvvycgTSFDPYQ--DDAHVKAFNAEFKKRV-EARLPgqyTLPAyydAGA 319
Cdd:pfam13433 214 taeDIPVMSFS--VAEEelagmgPEPLVGHL-----AAWNYFQslDTPENKAFVAAFKARYgDDRVT---NDPM---EAA 280

                         330       340       350
                  ....*....|....*....|....*....|.
gi 1113580614 320 YETVYMFADVLKKSGlkpDADVQALRSALRD 350
Cdd:pfam13433 281 YIGVHLWAQAVEKAG---TDDPDAVRQAMLG 308
PBP1_SBP-like cd06327
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ...
 31-381 1.07e-04

periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.


Pssm-ID: 380550 [Multi-domain]  Cd Length: 336  Bit Score: 43.71  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  31 KIGLSVEVTGAGAGF-GPHMQIGAEIAKDEinAAGGVNGHPIEFVIEDNQTKPELAVSAVRN-LARAGVVGIIGpLQTNQ 108
Cdd:cd06327     1 RIGVLTDLSGVYADLsGPGSVEAAKMAVED--FGGKVLGRPIEVVSADHQNKPDVASAIAREwYDRDGVDAIVD-VPNSA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 109 ARVAFSATNREK---LVSLTPGSNVPGLAAENR---PYAFRNSALLQVITDDMVAQVRKDYpnakrvvmvtdpkdaiqkF 182
Cdd:cd06327    78 VALAVQKLAKEKkkiAIVTGAGSSDLTGKACSPygvHWAYDTYALARGTVKALVKQGGKSW------------------F 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 183 FATV----------AAPPALTAAGFEIVNKDSYieiPYTDQDFSVHVTKIKALQPDVVLLSIFydrGVDFLKeAIRQ--- 249
Cdd:cd06327   140 FITAdyafghsleaDATAAVKAAGGKVVGSVRH---PLGTTDFSSFLLQAQASGADVIALANA---GADLVN-AVKQare 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 250 -GLKTPVITPTGWILEPV-------ARAAGDIVVycgTSFDPYQDDAhvkafNAEFKKRVEARLPGQytlPAYYDAGAYE 321
Cdd:cd06327   213 fGLTDGGQKLAALLLFITdihalglDAAQGLYLT---TAFYWDRDDA-----TRAWAKRFFARTGKM---PTMLQAGVYS 281

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 322 TVYMFADVLKKSGlkpDADVQALRSALRDglQSMKDFpgLGNKITINQEGDAIKPTLIYK 381
Cdd:cd06327   282 AVLHYLKAVKAAG---TDDADAVVAKMRE--MPVNDF--FAKNGRIRADGRVVHDMYLVQ 334
PBP1_SAP_GC-like cd06370
Ligand-binding domain of membrane bound guanylyl cyclases; Ligand-binding domain of membrane ...
 30-103 5.51e-04

Ligand-binding domain of membrane bound guanylyl cyclases; Ligand-binding domain of membrane bound guanylyl cyclases (GCs), which are known to be activated by sperm-activating peptides (SAPs), such as speract or resact. These ligand peptides are released by a range of invertebrates to stimulate the metabolism and motility of spermatozoa and are also potent chemoattractants. These GCs contain a single transmembrane segment, an extracellular ligand binding domain, and intracellular protein kinase-like and cyclase catalytic domains. GCs of insect and nematodes, which exhibit high sequence similarity to the speract receptor are also included in this model.


Pssm-ID: 380593 [Multi-domain]  Cd Length: 400  Bit Score: 41.85  E-value: 5.51e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1113580614  30 YKIGLSVEVTGAGAGFGPHMQI-GA-EIAKDEINAAGGV-NGHPIEFVIEDNQTKPELAVSAVRNLARAGVVGIIGP 103
Cdd:cd06370     1 ITIGYLTPYSGAGSYDRQGRVIsGAiTLAVDDVNNDPNLlPGHTLSFVWNDTRCDELLSIRAMTELWKRGVSAFIGP 77
PBP1_glutamate_receptors-like cd06269
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl ...
 54-251 1.86e-03

ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as natriuretic peptide receptors (NPRs), and N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of ionotropic glutamate rece; This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs), and the N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the ionotropic glutamate receptors, all of which are structurally similar and related to the periplasmic-binding fold type 1 family. The family C GPCRs consists of metabotropic glutamate receptor (mGluR), a calcium-sensing receptor (CaSR), gamma-aminobutyric acid receptor (GABAbR), the promiscuous L-alpha-amino acid receptor GPR6A, families of taste and pheromone receptors, and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids, ions, and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors, AMPA receptors, and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B), the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E, GC-F), and olfactory receptors (GC-D and GC-G).


Pssm-ID: 380493 [Multi-domain]  Cd Length: 332  Bit Score: 40.09  E-value: 1.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614  54 EIAKDEINAAG-GVNGHPIEFVIEDNQTKPELAV-SAVRNLARAGVVGIIGPLQTNQARVAFSATNREKLVSLTPGSNVP 131
Cdd:cd06269    23 ELALSDVNSRPdLLPKTTLGLAIRDSECNPTQALlSACDLLAAAKVVAILGPGCSASAAPVANLARHWDIPVLSYGATAP 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1113580614 132 GLAAENR-PYAFRN--SALLQVitDDMVAQVRKdyPNAKRVVMV---TDPKDAIQKFFATVAAppaltAAGFEIVNKDSY 205
Cdd:cd06269   103 GLSDKSRyAYFLRTvpPDSKQA--DAMLALVRR--LGWNKVVLIysdDEYGEFGLEGLEELFQ-----EKGGLITSRQSF 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1113580614 206 IEipYTDQDFSVHVTKIKALQPDVVLLSIFYDRGVDFLKEAIRQGL 251
Cdd:cd06269   174 DE--NKDDDLTKLLRNLRDTEARVIILLASPDTARSLMLEAKRLDM 217
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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