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Conserved domains on  [gi|1125296277|gb|OLC39883|]
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MAG: dehydrogenase [Candidatus Rokubacteria bacterium 13_1_40CM_4_69_5]

Protein Classification

YciI family protein( domain architecture ID 10008017)

YciI family protein similar to Haemophilus influenzae YciI (HI0828) and Burkholderia phenoliruptrix 5-chlorohydroxyhydroquinone dehydrochlorinase, which is involved in the biodegradation of 2,4,5-trichlorophenoxyacetate

CATH:  3.30.70.1060

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YCII COG3795
5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites ...
 1-121 9.04e-51

5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 443009 [Multi-domain]  Cd Length: 118  Bit Score: 157.25  E-value: 9.04e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125296277   1 MRFMIIVKATKDSEAEVMPigPAWEPVFAEMAKYHEELQRAGVLLDASGLQPSSKGWRIKYSGSKRTVIDGPFTEAKELV 80
Cdd:COG3795     1 MKYLLLIYADEEAEAGLSP--EEMEALMAAMGAFNEELAAAGVLVAGEGLQPPSTATTVRVRDGKPVVTDGPFAETKELL 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1125296277  81 AGYTLIQVKSREEALEWARRFPNPALeDGEIEVRQLYELDD 121
Cdd:COG3795    79 GGFYLIEVEDLDEAVEWAARCPAARG-GGTVEVRPVMEAPD 118
 
Name Accession Description Interval E-value
YCII COG3795
5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites ...
 1-121 9.04e-51

5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443009 [Multi-domain]  Cd Length: 118  Bit Score: 157.25  E-value: 9.04e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125296277   1 MRFMIIVKATKDSEAEVMPigPAWEPVFAEMAKYHEELQRAGVLLDASGLQPSSKGWRIKYSGSKRTVIDGPFTEAKELV 80
Cdd:COG3795     1 MKYLLLIYADEEAEAGLSP--EEMEALMAAMGAFNEELAAAGVLVAGEGLQPPSTATTVRVRDGKPVVTDGPFAETKELL 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1125296277  81 AGYTLIQVKSREEALEWARRFPNPALeDGEIEVRQLYELDD 121
Cdd:COG3795    79 GGFYLIEVEDLDEAVEWAARCPAARG-GGTVEVRPVMEAPD 118
YCII pfam03795
YCII-related domain; The majority of proteins in this family consist of a single copy of this ...
 2-118 1.37e-14

YCII-related domain; The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function. This family also now includes the family formerly known as the DGPF domain (COG3795). Although its function is unknown it is found fused to a sigma-70 factor family domain in Swiss:Q9A8M4. Suggesting that this domain plays a role in transcription initiation (Bateman A per. obs.). This domain is named after the most conserved motif in the alignment.


Pssm-ID: 397734  Cd Length: 94  Bit Score: 64.69  E-value: 1.37e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125296277   2 RFMIIVKATKDSEAEVMPIGPAwepvfaeMAKYHEELQRAGVLLdASGlqpsskgwrikysgsKRTVIDGPFTEAKELVA 81
Cdd:pfam03795   1 LYAILAYDKPASLEERAALRAA-------HLAYLEQLKKEGVLL-ASG---------------PTLVIDGPFAETKEQLG 57

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1125296277  82 GYTLIQVKSREEALEWARRFPNPalEDGEIEVRQLYE 118
Cdd:pfam03795  58 GFYIIEAADLDEAIAIAAGDPFV--AAGLYEERPVKE 92
 
Name Accession Description Interval E-value
YCII COG3795
5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites ...
 1-121 9.04e-51

5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443009 [Multi-domain]  Cd Length: 118  Bit Score: 157.25  E-value: 9.04e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125296277   1 MRFMIIVKATKDSEAEVMPigPAWEPVFAEMAKYHEELQRAGVLLDASGLQPSSKGWRIKYSGSKRTVIDGPFTEAKELV 80
Cdd:COG3795     1 MKYLLLIYADEEAEAGLSP--EEMEALMAAMGAFNEELAAAGVLVAGEGLQPPSTATTVRVRDGKPVVTDGPFAETKELL 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1125296277  81 AGYTLIQVKSREEALEWARRFPNPALeDGEIEVRQLYELDD 121
Cdd:COG3795    79 GGFYLIEVEDLDEAVEWAARCPAARG-GGTVEVRPVMEAPD 118
YCII pfam03795
YCII-related domain; The majority of proteins in this family consist of a single copy of this ...
 2-118 1.37e-14

YCII-related domain; The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function. This family also now includes the family formerly known as the DGPF domain (COG3795). Although its function is unknown it is found fused to a sigma-70 factor family domain in Swiss:Q9A8M4. Suggesting that this domain plays a role in transcription initiation (Bateman A per. obs.). This domain is named after the most conserved motif in the alignment.


Pssm-ID: 397734  Cd Length: 94  Bit Score: 64.69  E-value: 1.37e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125296277   2 RFMIIVKATKDSEAEVMPIGPAwepvfaeMAKYHEELQRAGVLLdASGlqpsskgwrikysgsKRTVIDGPFTEAKELVA 81
Cdd:pfam03795   1 LYAILAYDKPASLEERAALRAA-------HLAYLEQLKKEGVLL-ASG---------------PTLVIDGPFAETKEQLG 57

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1125296277  82 GYTLIQVKSREEALEWARRFPNPalEDGEIEVRQLYE 118
Cdd:pfam03795  58 GFYIIEAADLDEAIAIAAGDPFV--AAGLYEERPVKE 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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