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Conserved domains on  [gi|1125366695|gb|OLD05071|]
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hypothetical protein AUJ07_02450 [Crenarchaeota archaeon 13_1_40CM_3_53_5]

Protein Classification

ankyrin repeat domain-containing protein( domain architecture ID 11429852)

ankyrin repeat domain-containing protein; ANK proteins mediate specific protein-protein interactions without necessarily recognizing specific primary sequences which allows for one ankyrin repeat domain to recognize and bind to a variety of intracellular substrates and may be involved in a wide array of functions

Gene Ontology:  GO:0005515
PubMed:  17176038
SCOP:  4000366

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
8-194 2.12e-16

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 75.38  E-value: 2.12e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695   8 NPDLVREFVIAGHGNLERVKQLLAESPELLNAaypwKEDDRETAIQAAAQVGSVSVAEFLLAKGAPLDIC---------T 78
Cdd:COG0666    51 DALGALLLLAAALAGDLLVALLLLAAGADINA----KDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARdkdgetplhL 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695  79 AAMLGRKDQVEKFLAQDpAKIHAKGAHGIPLLTHAGFGRNLELVEFLIARGATV-----GLSPALHNAVSRDDTWIVTWL 153
Cdd:COG0666   127 AAYNGNLEIVKLLLEAG-ADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVnardnDGETPLHLAAENGHLEIVKLL 205

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1125366695 154 LENtRPDLAWKNFQGKTALKLAEERQNSEMTKLLREHGARE 194
Cdd:COG0666   206 LEA-GADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
8-194 2.12e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 75.38  E-value: 2.12e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695   8 NPDLVREFVIAGHGNLERVKQLLAESPELLNAaypwKEDDRETAIQAAAQVGSVSVAEFLLAKGAPLDIC---------T 78
Cdd:COG0666    51 DALGALLLLAAALAGDLLVALLLLAAGADINA----KDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARdkdgetplhL 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695  79 AAMLGRKDQVEKFLAQDpAKIHAKGAHGIPLLTHAGFGRNLELVEFLIARGATV-----GLSPALHNAVSRDDTWIVTWL 153
Cdd:COG0666   127 AAYNGNLEIVKLLLEAG-ADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVnardnDGETPLHLAAENGHLEIVKLL 205

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1125366695 154 LENtRPDLAWKNFQGKTALKLAEERQNSEMTKLLREHGARE 194
Cdd:COG0666   206 LEA-GADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245
Ank_2 pfam12796
Ankyrin repeats (3 copies);
110-192 5.80e-07

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 45.88  E-value: 5.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695 110 LTHAGFGRNLELVEFLIARGATVGLSP-----ALHNAVSRDDTWIVTWLLENTRPDLawkNFQGKTALKLAEERQNSEMT 184
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDkngrtALHLAAKNGHLEIVKLLLEHADVNL---KDNGRTALHYAARSGHLEIV 77


                  ....*...
gi 1125366695 185 KLLREHGA 192
Cdd:pfam12796  78 KLLLEKGA 85
PHA02743 PHA02743
Viral ankyrin protein; Provisional
 138-192 4.76e-05

Viral ankyrin protein; Provisional


Pssm-ID: 222925 [Multi-domain]  Cd Length: 166  Bit Score: 42.11  E-value: 4.76e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1125366695 138 LHNAVSRDDTWIVTWLLENTRPDLAWKNFQGKTALKLAEERQNSEMTKLLREHGA 192
Cdd:PHA02743   98 LHIAASTKNYELAEWLCRQLGVNLGAINYQHETAYHIAYKMRDRRMMEILRANGA 152
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
8-194 2.12e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 75.38  E-value: 2.12e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695   8 NPDLVREFVIAGHGNLERVKQLLAESPELLNAaypwKEDDRETAIQAAAQVGSVSVAEFLLAKGAPLDIC---------T 78
Cdd:COG0666    51 DALGALLLLAAALAGDLLVALLLLAAGADINA----KDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARdkdgetplhL 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695  79 AAMLGRKDQVEKFLAQDpAKIHAKGAHGIPLLTHAGFGRNLELVEFLIARGATV-----GLSPALHNAVSRDDTWIVTWL 153
Cdd:COG0666   127 AAYNGNLEIVKLLLEAG-ADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVnardnDGETPLHLAAENGHLEIVKLL 205

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1125366695 154 LENtRPDLAWKNFQGKTALKLAEERQNSEMTKLLREHGARE 194
Cdd:COG0666   206 LEA-GADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
44-192 1.33e-14

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 70.37  E-value: 1.33e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695  44 KEDDRETAIQAAAQVGSVSVAEFLLAKGAPLDI---------CTAAMLGRKDQVEKFLAQDpAKIHAKGAHGIPLLTHAG 114
Cdd:COG0666    50 ADALGALLLLAAALAGDLLVALLLLAAGADINAkddggntllHAAARNGDLEIVKLLLEAG-ADVNARDKDGETPLHLAA 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695 115 FGRNLELVEFLIARGATV-----GLSPALHNAVSRDDTWIVTWLLENtRPDLAWKNFQGKTALKLAEERQNSEMTKLLRE 189
Cdd:COG0666   129 YNGNLEIVKLLLEAGADVnaqdnDGNTPLHLAAANGNLEIVKLLLEA-GADVNARDNDGETPLHLAAENGHLEIVKLLLE 207


                  ...
gi 1125366695 190 HGA 192
Cdd:COG0666   208 AGA 210
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
15-193 4.39e-14

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 68.83  E-value: 4.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695  15 FVIAGHGNLERVKQLLaESPELLNAaypwKEDDRETAIQAAAQVGSVSVAEFLLAKGAPLDICT---------AAMLGRK 85
Cdd:COG0666    92 HAAARNGDLEIVKLLL-EAGADVNA----RDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDndgntplhlAAANGNL 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695  86 DQVEKFLAQDpAKIHAKGAHGIPLLTHAGFGRNLELVEFLIARGATVGL-----SPALHNAVSRDDTWIVTWLLENtRPD 160
Cdd:COG0666   167 EIVKLLLEAG-ADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAkdndgKTALDLAAENGNLEIVKLLLEA-GAD 244

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1125366695 161 LAWKNFQGKTALKLAEERQNSEMTKLLREHGAR 193
Cdd:COG0666   245 LNAKDKDGLTALLLAAAAGAALIVKLLLLALLL 277
Ank_2 pfam12796
Ankyrin repeats (3 copies);
110-192 5.80e-07

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 45.88  E-value: 5.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695 110 LTHAGFGRNLELVEFLIARGATVGLSP-----ALHNAVSRDDTWIVTWLLENTRPDLawkNFQGKTALKLAEERQNSEMT 184
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDkngrtALHLAAKNGHLEIVKLLLEHADVNL---KDNGRTALHYAARSGHLEIV 77


                  ....*...
gi 1125366695 185 KLLREHGA 192
Cdd:pfam12796  78 KLLLEKGA 85
PHA02743 PHA02743
Viral ankyrin protein; Provisional
 138-192 4.76e-05

Viral ankyrin protein; Provisional


Pssm-ID: 222925 [Multi-domain]  Cd Length: 166  Bit Score: 42.11  E-value: 4.76e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1125366695 138 LHNAVSRDDTWIVTWLLENTRPDLAWKNFQGKTALKLAEERQNSEMTKLLREHGA 192
Cdd:PHA02743   98 LHIAASTKNYELAEWLCRQLGVNLGAINYQHETAYHIAYKMRDRRMMEILRANGA 152
PHA02741 PHA02741
hypothetical protein; Provisional
 119-192 1.21e-04

hypothetical protein; Provisional


Pssm-ID: 165108 [Multi-domain]  Cd Length: 169  Bit Score: 40.80  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695 119 LELVEFLIARGA------TVGLSPALHNAVSRDDTWIVTWLLENTRPDLAWKNFQGKTALKLAEERQNSEMTKLLREHGA 192
Cdd:PHA02741   77 AEIIDHLIELGAdinaqeMLEGDTALHLAAHRRDHDLAEWLCCQPGIDLHFCNADNKSPFELAIDNEDVAMMQILREIVA 156
Ank_2 pfam12796
Ankyrin repeats (3 copies);
138-194 2.93e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 38.56  E-value: 2.93e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1125366695 138 LHNAVSRDDTWIVTWLLENtRPDLAWKNFQGKTALKLAEERQNSEMTKLLREHGARE 194
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLEN-GADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVN 56
Ank_2 pfam12796
Ankyrin repeats (3 copies);
79-156 6.45e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 37.40  E-value: 6.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695  79 AAMLGRKDQVeKFLAQDPAKIHAKGAHGIPLLTHAGFGRNLELVEFLI----ARGATVGLSPaLHNAVSRDDTWIVTWLL 154
Cdd:pfam12796   4 AAKNGNLELV-KLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLehadVNLKDNGRTA-LHYAARSGHLEIVKLLL 81


                  ..
gi 1125366695 155 EN 156
Cdd:pfam12796  82 EK 83
Ank_2 pfam12796
Ankyrin repeats (3 copies);
18-102 6.71e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 37.40  E-value: 6.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695  18 AGHGNLERVKQLLAESPELLnaaypWKEDDRETAIQAAAQVGSVSVAEFLLAKGA---------PLDIctAAMLGRKDQV 88
Cdd:pfam12796   5 AKNGNLELVKLLLENGADAN-----LQDKNGRTALHLAAKNGHLEIVKLLLEHADvnlkdngrtALHY--AARSGHLEIV 77

                          90
                  ....*....|....
gi 1125366695  89 eKFLAQDPAKIHAK 102
Cdd:pfam12796  78 -KLLLEKGADINVK 90
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 45-175 1.34e-03

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 38.71  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695  45 EDDRETAIQAAAQVGSVSVAEFLLAKGAP---LDICT-----AAMLGRKDQVEKFLAQDPAKIHAKGAHG-IPLLTHAGF 115
Cdd:PHA02878  165 RHKGNTALHYATENKDQRLTELLLSYGANvniPDKTNnsplhHAVKHYNKPIVHILLENGASTDARDKCGnTPLHISVGY 244

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1125366695 116 GRNLELVEFLIARGATV-------GLSPaLHNAVSRDDtwiVTWLLENTRPDLAWKNFQGKTALKLA 175
Cdd:PHA02878  245 CKDYDILKLLLEHGVDVnaksyilGLTA-LHSSIKSER---KLKLLLEYGADINSLNSYKLTPLSSA 307
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 106-192 1.57e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 38.43  E-value: 1.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125366695 106 GIPLLTHAGFGRNLELVEFLIARGA-----TVGLSPALHNAVSRDDTWIVTWLLENTR--PDLAWKNfqGKTALKLAEER 178
Cdd:PHA02875   35 GISPIKLAMKFRDSEAIKLLMKHGAipdvkYPDIESELHDAVEEGDVKAVEELLDLGKfaDDVFYKD--GMTPLHLATIL 112

                          90
                  ....*....|....
gi 1125366695 179 QNSEMTKLLREHGA 192
Cdd:PHA02875  113 KKLDIMKLLIARGA 126
PHA02736 PHA02736
Viral ankyrin protein; Provisional
 138-193 2.10e-03

Viral ankyrin protein; Provisional


Pssm-ID: 165103 [Multi-domain]  Cd Length: 154  Bit Score: 37.16  E-value: 2.10e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1125366695 138 LHNAVSRDDTWIVTWLLENTRPDLAWKNFQGKTALKLAEERQNSEMTKLLREHGAR 193
Cdd:PHA02736   96 LHIAVYTQNYELATWLCNQPGVNMEILNYAFKTPYYVACERHDAKMMNILRAKGAQ 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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