NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1137940905|gb|OMS60659|]
View 

peptidoglycan-binding protein LysM [Burkholderia pseudomallei]

Protein Classification

LysM and BON domain-containing protein( domain architecture ID 11485265)

LysM and BON domain-containing protein similar to Escherichia coli potassium binding protein Kbp (YgaU), a highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+)

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK11198 PRK11198
LysM domain/BON superfamily protein; Provisional
 1-154 1.67e-61

LysM domain/BON superfamily protein; Provisional


:

Pssm-ID: 236880 [Multi-domain]  Cd Length: 147  Bit Score: 186.27  E-value: 1.67e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1137940905   1 MGLLSFIKEAGEKLLGKSDEQAATDPAAANqtaadaIKNYISAQGLDTSNLTVAFDGasRTVTLTGSVADLDTKAKVKVA 80
Cdd:PRK11198    1 MGLFSFVKEAGEKLFDAVTAQADNEDAADA------LKEHISKQGLGDADVNVQVED--GKATVSGDAASQEAKEKILLA 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1137940905  81 AGNVQGVAGV-NDDDLQPDDPQVQYHDVVSGDNLWKIAEKYYGDGSKNDAIFQANRPMLSSPDRIYPGQKLVIPP 154
Cdd:PRK11198   73 VGNIQGIASVdDQVKVATPAPESQFYTVKSGDTLSAIAKKVYGNANKYNKIFEANKPMLKSPDKIYPGQVLRIPE 147
 
Name Accession Description Interval E-value
PRK11198 PRK11198
LysM domain/BON superfamily protein; Provisional
 1-154 1.67e-61

LysM domain/BON superfamily protein; Provisional


Pssm-ID: 236880 [Multi-domain]  Cd Length: 147  Bit Score: 186.27  E-value: 1.67e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1137940905   1 MGLLSFIKEAGEKLLGKSDEQAATDPAAANqtaadaIKNYISAQGLDTSNLTVAFDGasRTVTLTGSVADLDTKAKVKVA 80
Cdd:PRK11198    1 MGLFSFVKEAGEKLFDAVTAQADNEDAADA------LKEHISKQGLGDADVNVQVED--GKATVSGDAASQEAKEKILLA 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1137940905  81 AGNVQGVAGV-NDDDLQPDDPQVQYHDVVSGDNLWKIAEKYYGDGSKNDAIFQANRPMLSSPDRIYPGQKLVIPP 154
Cdd:PRK11198   73 VGNIQGIASVdDQVKVATPAPESQFYTVKSGDTLSAIAKKVYGNANKYNKIFEANKPMLKSPDKIYPGQVLRIPE 147
XkdP COG1652
Cytoplasmic potassium-binding protein Kbp/XkdP/YgaU, contains LysM domain [Inorganic ion ...
 50-154 1.71e-23

Cytoplasmic potassium-binding protein Kbp/XkdP/YgaU, contains LysM domain [Inorganic ion transport and metabolism];


Pssm-ID: 441258 [Multi-domain]  Cd Length: 163  Bit Score: 90.07  E-value: 1.71e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1137940905  50 NLTVAFDGASRTVTLTGSVADLDTKAKVKVAAGNVQGVAGVNDDDLQPDDPQVQYHDVVSGDNLWKIAEKYYGDGSKNDA 129
Cdd:COG1652    57 AGLAAAVAAAAAAAVLIAPVAVMRAGAAAKLSPAVTVAEEAAAPSAELAPDAPKTYTVKPGDTLWGIAKRFYGDPARWPE 136

                          90       100
                  ....*....|....*....|....*
gi 1137940905 130 IFQANRPMLSSPDRIYPGQKLVIPP 154
Cdd:COG1652   137 IAEANRDQIKNPDLIYPGQVLRIPA 161
LysM cd00118
Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain ...
 103-152 1.16e-11

Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.


Pssm-ID: 212030 [Multi-domain]  Cd Length: 45  Bit Score: 55.95  E-value: 1.16e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1137940905 103 QYHDVVSGDNLWKIAEKYYGDgskNDAIFQANRpmLSSPDRIYPGQKLVI 152
Cdd:cd00118     1 KTYTVKPGDTLWSIAKKYGVT---VEELAAANP--LINPDCIYPGQKLKI 45
LysM smart00257
Lysin motif;
104-152 3.31e-09

Lysin motif;


Pssm-ID: 197609 [Multi-domain]  Cd Length: 44  Bit Score: 49.75  E-value: 3.31e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1137940905  104 YHDVVSGDNLWKIAEKYYGDGSKndaIFQANRpmLSSPDRIYPGQKLVI 152
Cdd:smart00257   1 TYTVKKGDTLSSIARRYGISVSD---LLELNN--ILDPDNLQVGQKLKI 44
LysM pfam01476
LysM domain; The LysM (lysin motif) domain is about 40 residues long. It is found in a variety ...
 105-153 1.09e-08

LysM domain; The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.


Pssm-ID: 396179 [Multi-domain]  Cd Length: 43  Bit Score: 48.16  E-value: 1.09e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1137940905 105 HDVVSGDNLWKIAEKYygdGSKNDAIFQANRpmLSSPDrIYPGQKLVIP 153
Cdd:pfam01476   1 YTVKKGDTLSSIAKRY---GITVEQLAELNG--LSSPN-LYVGQKLKIP 43
lipo_LipL71 NF033163
lipoprotein LipL71; Members of this family are lipoprotein LipL71, also known as LruA, as ...
 108-156 8.87e-08

lipoprotein LipL71; Members of this family are lipoprotein LipL71, also known as LruA, as described in Leptospira interrogans but found broadly in the genus Leptospira. Close homologs that are not lipoproteins by sequence are likely defective in their reported coding region.


Pssm-ID: 467971 [Multi-domain]  Cd Length: 472  Bit Score: 50.03  E-value: 8.87e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1137940905 108 VSGDNLWKIA--EKYYGDGSKNDAIFQANRPMLSSPDRIYPGQKLVIPPQS 156
Cdd:NF033163  413 VPADCLWRIAdrKDHYGTSKLWRRIYEANRKKIRNPNLIYPKQVLLIPPKK 463
 
Name Accession Description Interval E-value
PRK11198 PRK11198
LysM domain/BON superfamily protein; Provisional
 1-154 1.67e-61

LysM domain/BON superfamily protein; Provisional


Pssm-ID: 236880 [Multi-domain]  Cd Length: 147  Bit Score: 186.27  E-value: 1.67e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1137940905   1 MGLLSFIKEAGEKLLGKSDEQAATDPAAANqtaadaIKNYISAQGLDTSNLTVAFDGasRTVTLTGSVADLDTKAKVKVA 80
Cdd:PRK11198    1 MGLFSFVKEAGEKLFDAVTAQADNEDAADA------LKEHISKQGLGDADVNVQVED--GKATVSGDAASQEAKEKILLA 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1137940905  81 AGNVQGVAGV-NDDDLQPDDPQVQYHDVVSGDNLWKIAEKYYGDGSKNDAIFQANRPMLSSPDRIYPGQKLVIPP 154
Cdd:PRK11198   73 VGNIQGIASVdDQVKVATPAPESQFYTVKSGDTLSAIAKKVYGNANKYNKIFEANKPMLKSPDKIYPGQVLRIPE 147
XkdP COG1652
Cytoplasmic potassium-binding protein Kbp/XkdP/YgaU, contains LysM domain [Inorganic ion ...
 50-154 1.71e-23

Cytoplasmic potassium-binding protein Kbp/XkdP/YgaU, contains LysM domain [Inorganic ion transport and metabolism];


Pssm-ID: 441258 [Multi-domain]  Cd Length: 163  Bit Score: 90.07  E-value: 1.71e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1137940905  50 NLTVAFDGASRTVTLTGSVADLDTKAKVKVAAGNVQGVAGVNDDDLQPDDPQVQYHDVVSGDNLWKIAEKYYGDGSKNDA 129
Cdd:COG1652    57 AGLAAAVAAAAAAAVLIAPVAVMRAGAAAKLSPAVTVAEEAAAPSAELAPDAPKTYTVKPGDTLWGIAKRFYGDPARWPE 136

                          90       100
                  ....*....|....*....|....*
gi 1137940905 130 IFQANRPMLSSPDRIYPGQKLVIPP 154
Cdd:COG1652   137 IAEANRDQIKNPDLIYPGQVLRIPA 161
LysM cd00118
Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain ...
 103-152 1.16e-11

Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.


Pssm-ID: 212030 [Multi-domain]  Cd Length: 45  Bit Score: 55.95  E-value: 1.16e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1137940905 103 QYHDVVSGDNLWKIAEKYYGDgskNDAIFQANRpmLSSPDRIYPGQKLVI 152
Cdd:cd00118     1 KTYTVKPGDTLWSIAKKYGVT---VEELAAANP--LINPDCIYPGQKLKI 45
LysM smart00257
Lysin motif;
104-152 3.31e-09

Lysin motif;


Pssm-ID: 197609 [Multi-domain]  Cd Length: 44  Bit Score: 49.75  E-value: 3.31e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1137940905  104 YHDVVSGDNLWKIAEKYYGDGSKndaIFQANRpmLSSPDRIYPGQKLVI 152
Cdd:smart00257   1 TYTVKKGDTLSSIARRYGISVSD---LLELNN--ILDPDNLQVGQKLKI 44
LysM COG1388
LysM repeat [Cell wall/membrane/envelope biogenesis];
8-153 1.02e-08

LysM repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440998 [Multi-domain]  Cd Length: 156  Bit Score: 51.25  E-value: 1.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1137940905   8 KEAGEKLLGKSDEQAATDPAAANQTAADAIKNYISAQGLDTSNLTVAFDGASRTVTLTGSVADLDTKAKVKVAAGnvQGV 87
Cdd:COG1388    17 LTLLAALLLLAAALAAVALLLLAALAPAGLSLAAALNGEALLLLLPAAAAAAKAALAAAPEAAAAAAARYTVKSG--DTL 94

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1137940905  88 AGVNDDDLQPDDPQVQYHDVVSGDNLWKIAEKYygdGSKNDAIFQANRpmLSSpDRIYPGQKLVIP 153
Cdd:COG1388    95 SGIARRYGAAAAPSPVTYTVKKGDTLWSIARRY---GVSVEELKRWNG--LSS-DTIRPGQKLKIP 154
LysM pfam01476
LysM domain; The LysM (lysin motif) domain is about 40 residues long. It is found in a variety ...
 105-153 1.09e-08

LysM domain; The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.


Pssm-ID: 396179 [Multi-domain]  Cd Length: 43  Bit Score: 48.16  E-value: 1.09e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1137940905 105 HDVVSGDNLWKIAEKYygdGSKNDAIFQANRpmLSSPDrIYPGQKLVIP 153
Cdd:pfam01476   1 YTVKKGDTLSSIAKRY---GITVEQLAELNG--LSSPN-LYVGQKLKIP 43
lipo_LipL71 NF033163
lipoprotein LipL71; Members of this family are lipoprotein LipL71, also known as LruA, as ...
 108-156 8.87e-08

lipoprotein LipL71; Members of this family are lipoprotein LipL71, also known as LruA, as described in Leptospira interrogans but found broadly in the genus Leptospira. Close homologs that are not lipoproteins by sequence are likely defective in their reported coding region.


Pssm-ID: 467971 [Multi-domain]  Cd Length: 472  Bit Score: 50.03  E-value: 8.87e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1137940905 108 VSGDNLWKIA--EKYYGDGSKNDAIFQANRPMLSSPDRIYPGQKLVIPPQS 156
Cdd:NF033163  413 VPADCLWRIAdrKDHYGTSKLWRRIYEANRKKIRNPNLIYPKQVLLIPPKK 463
PRK14125 PRK14125
cell division suppressor protein YneA; Provisional
 106-153 1.18e-04

cell division suppressor protein YneA; Provisional


Pssm-ID: 184523 [Multi-domain]  Cd Length: 103  Bit Score: 39.24  E-value: 1.18e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1137940905 106 DVVSGDNLWKIAEKYYG--DGSKNDAI---FQANRpmLSSpDRIYPGQKLVIP 153
Cdd:PRK14125   40 TVQEGDTLWALADQYAGkhHMAKNEFIewvEDVNN--LPS-GHIKAGDKLVIP 89
OsmY COG2823
Osmotically-inducible protein OsmY, contains BON domain [Cell wall/membrane/envelope ...
 43-91 4.79e-04

Osmotically-inducible protein OsmY, contains BON domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442071 [Multi-domain]  Cd Length: 157  Bit Score: 38.49  E-value: 4.79e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1137940905  43 AQGLDTSNLTV-AFDGasrTVTLTGSVADLDTKAKVKVAAGNVQGVAGVN 91
Cdd:COG2823    34 DPGLDAADINVtVYNG---VVTLTGQVPSEAEKDRAEEIARGVPGVKSVV 80
BON pfam04972
BON domain; This domain is found in a family of osmotic shock protection proteins. It is also ...
 43-90 7.54e-03

BON domain; This domain is found in a family of osmotic shock protection proteins. It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes.


Pssm-ID: 428229 [Multi-domain]  Cd Length: 69  Bit Score: 33.34  E-value: 7.54e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1137940905  43 AQGLDTSNLTVAFDGasRTVTLTGSVADLDTKAKVKVAAGNVQGVAGV 90
Cdd:pfam04972  16 DPGLDAADINVTVEN--GVVTLSGTVPSEAEKEKAEEIARNVAGVKKV 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH