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Conserved domains on  [gi|1193849578|gb|OTW54092|]
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methyltransferase [Bacillus thuringiensis serovar mexicanensis]

Protein Classification

O-methyltransferase( domain architecture ID 11467877)

O-methyltransferase of the class I-like SAM-binding methyltransferase superfamily, such as catechol O-methyltransferases that can use various catechol-like compounds

CATH:  2.20.25.110
EC:  2.1.1.-|2.1.-.-
Gene Ontology:  GO:0008757|GO:0032259|GO:1904047|GO:0008168|GO:0008171
PubMed:  12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 37-196 1.70e-51

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


:

Pssm-ID: 443298  Cd Length: 173  Bit Score: 163.43  E-value: 1.70e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  37 REMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEEtNGNVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAF 116
Cdd:COG4122     2 PEQGRLLYLLARLLGAKRILEIGTGTGYSTLWLARALPD-DGRLTTIEIDPERAAIARENFARAGLADRIRLILGDALEV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578 117 LDSQLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSH------------ANELAEFIKMIEEDKMFETVLL 184
Cdd:COG4122    81 LPRLADGPFDLVFIDADKSNYPDYLELALPLLRPGGLIVADNVLWHgrvadparrdpsTRAIREFNEYLREDPRLESVLL 160

                         170
                  ....*....|..
gi 1193849578 185 AFQNGAFVARKK 196
Cdd:COG4122   161 PIGDGLLLARKR 172
 
Name Accession Description Interval E-value
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 37-196 1.70e-51

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 163.43  E-value: 1.70e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  37 REMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEEtNGNVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAF 116
Cdd:COG4122     2 PEQGRLLYLLARLLGAKRILEIGTGTGYSTLWLARALPD-DGRLTTIEIDPERAAIARENFARAGLADRIRLILGDALEV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578 117 LDSQLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSH------------ANELAEFIKMIEEDKMFETVLL 184
Cdd:COG4122    81 LPRLADGPFDLVFIDADKSNYPDYLELALPLLRPGGLIVADNVLWHgrvadparrdpsTRAIREFNEYLREDPRLESVLL 160

                         170
                  ....*....|..
gi 1193849578 185 AFQNGAFVARKK 196
Cdd:COG4122   161 PIGDGLLLARKR 172
Methyltransf_3 pfam01596
O-methyltransferase; Members of this family are O-methyltransferases. The family includes ...
 15-196 2.04e-24

O-methyltransferase; Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production.


Pssm-ID: 396257 [Multi-domain]  Cd Length: 203  Bit Score: 94.87  E-value: 2.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  15 EQYGEEHDRNKKTREEKLRN------ISREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEEtNGNVTTVELSSE 88
Cdd:pfam01596   1 ETSAYEHEYLKELREETAKLplapmqVSPDEGQFLGMLVKLTGAKNVLEIGVFTGYSALAMALALPE-DGKITAIDIDPE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  89 RVGEALANFENANLLQRIDVHNQEAGAFLDS----QLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNA----- 159
Cdd:pfam01596  80 AYEIAKKFIQKAGVAHKISFILGPALKVLEQltqdKPLPEFDFIFIDADKSNYPNYYERLLELLKVGGLMAIDNTlwhgk 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1193849578 160 -------TSHANELAEFIKMIEEDKMFETVLLAFQNGAFVARKK 196
Cdd:pfam01596 160 vtepddqEAKTQRLQEFNKDLAQDPRVEISVIPVGDGITLCRKI 203
PLN02781 PLN02781
Probable caffeoyl-CoA O-methyltransferase
 5-158 6.22e-16

Probable caffeoyl-CoA O-methyltransferase


Pssm-ID: 215417  Cd Length: 234  Bit Score: 72.93  E-value: 6.22e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578   5 DTLNSLLFQLEQYGEEHDRNKKTRE---EKLRNISrEM------GQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEE 75
Cdd:PLN02781   14 EALKQYIMETSAYPREHELLKELREatvQKYGNLS-EMevpvdeGLFLSMLVKIMNAKNTLEIGVFTGYSLLTTALALPE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  76 tNGNVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDHS----FDFIFLDSERTQYMWWLEHIKRILQPK 151
Cdd:PLN02781   93 -DGRITAIDIDKEAYEVGLEFIKKAGVDHKINFIQSDALSALDQLLNNDpkpeFDFAFVDADKPNYVHFHEQLLKLVKVG 171


                  ....*..
gi 1193849578 152 GLLVVDN 158
Cdd:PLN02781  172 GIIAFDN 178
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 54-156 9.54e-09

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 50.89  E-value: 9.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  54 NILEIGTSNGYSTLWLADAVeetNGNVTTVELSSERVGEALANfENANLLQRIDVHNQEAGAFLDsQLDHSFDFIFLDSE 133
Cdd:cd02440     1 RVLDLGCGTGALALALASGP---GARVTGVDISPVALELARKA-AAALLADNVEVLKGDAEELPP-EADESFDVIISDPP 75

                          90       100       110
                  ....*....|....*....|....*....|
gi 1193849578 134 rtqYMWWLEHIKRILQ-------PKGLLVV 156
Cdd:cd02440    76 ---LHHLVEDLARFLEearrllkPGGVLVL 102
 
Name Accession Description Interval E-value
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 37-196 1.70e-51

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 163.43  E-value: 1.70e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  37 REMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEEtNGNVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAF 116
Cdd:COG4122     2 PEQGRLLYLLARLLGAKRILEIGTGTGYSTLWLARALPD-DGRLTTIEIDPERAAIARENFARAGLADRIRLILGDALEV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578 117 LDSQLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSH------------ANELAEFIKMIEEDKMFETVLL 184
Cdd:COG4122    81 LPRLADGPFDLVFIDADKSNYPDYLELALPLLRPGGLIVADNVLWHgrvadparrdpsTRAIREFNEYLREDPRLESVLL 160

                         170
                  ....*....|..
gi 1193849578 185 AFQNGAFVARKK 196
Cdd:COG4122   161 PIGDGLLLARKR 172
Methyltransf_3 pfam01596
O-methyltransferase; Members of this family are O-methyltransferases. The family includes ...
 15-196 2.04e-24

O-methyltransferase; Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production.


Pssm-ID: 396257 [Multi-domain]  Cd Length: 203  Bit Score: 94.87  E-value: 2.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  15 EQYGEEHDRNKKTREEKLRN------ISREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEEtNGNVTTVELSSE 88
Cdd:pfam01596   1 ETSAYEHEYLKELREETAKLplapmqVSPDEGQFLGMLVKLTGAKNVLEIGVFTGYSALAMALALPE-DGKITAIDIDPE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  89 RVGEALANFENANLLQRIDVHNQEAGAFLDS----QLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNA----- 159
Cdd:pfam01596  80 AYEIAKKFIQKAGVAHKISFILGPALKVLEQltqdKPLPEFDFIFIDADKSNYPNYYERLLELLKVGGLMAIDNTlwhgk 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1193849578 160 -------TSHANELAEFIKMIEEDKMFETVLLAFQNGAFVARKK 196
Cdd:pfam01596 160 vtepddqEAKTQRLQEFNKDLAQDPRVEISVIPVGDGITLCRKI 203
Methyltransf_24 pfam13578
Methyltransferase domain; This family appears to be a methyltransferase domain.
 56-158 5.25e-17

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 433324 [Multi-domain]  Cd Length: 106  Bit Score: 72.73  E-value: 5.25e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  56 LEIGTSNGYSTLWLADAVEETN-GNVTTVELsSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDS-- 132
Cdd:pfam13578   1 VEIGTYSGVSTLWLAAALRDNGlGRLTAVDP-DPGAEEAGALLRKAGLDDRVRLIVGDSREALPSLADGPIDLLFIDGdh 79

                          90       100
                  ....*....|....*....|....*.
gi 1193849578 133 ERTQYMWWLEHIKRILQPKGLLVVDN 158
Cdd:pfam13578  80 TYEAVLNDLELWLPRLAPGGVILFHD 105
PLN02781 PLN02781
Probable caffeoyl-CoA O-methyltransferase
 5-158 6.22e-16

Probable caffeoyl-CoA O-methyltransferase


Pssm-ID: 215417  Cd Length: 234  Bit Score: 72.93  E-value: 6.22e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578   5 DTLNSLLFQLEQYGEEHDRNKKTRE---EKLRNISrEM------GQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEE 75
Cdd:PLN02781   14 EALKQYIMETSAYPREHELLKELREatvQKYGNLS-EMevpvdeGLFLSMLVKIMNAKNTLEIGVFTGYSLLTTALALPE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  76 tNGNVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDHS----FDFIFLDSERTQYMWWLEHIKRILQPK 151
Cdd:PLN02781   93 -DGRITAIDIDKEAYEVGLEFIKKAGVDHKINFIQSDALSALDQLLNNDpkpeFDFAFVDADKPNYVHFHEQLLKLVKVG 171


                  ....*..
gi 1193849578 152 GLLVVDN 158
Cdd:PLN02781  172 GIIAFDN 178
PLN02589 PLN02589
caffeoyl-CoA O-methyltransferase
 5-158 2.06e-15

caffeoyl-CoA O-methyltransferase


Pssm-ID: 166230  Cd Length: 247  Bit Score: 71.95  E-value: 2.06e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578   5 DTLNSLLFQLEQYGEEHDRNKKTREEKLR---NI---SREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEEtNG 78
Cdd:PLN02589   27 DALYQYILETSVYPREPESMKELRELTAKhpwNImttSADEGQFLNMLLKLINAKNTMEIGVYTGYSLLATALALPE-DG 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  79 NVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDH-----SFDFIFLDSERTQYMWWLEHIKRILQPKGL 153
Cdd:PLN02589  106 KILAMDINRENYELGLPVIQKAGVAHKIDFREGPALPVLDQMIEDgkyhgTFDFIFVDADKDNYINYHKRLIDLVKVGGV 185


                  ....*
gi 1193849578 154 LVVDN 158
Cdd:PLN02589  186 IGYDN 190
PLN02476 PLN02476
O-methyltransferase
 25-196 8.42e-14

O-methyltransferase


Pssm-ID: 178094  Cd Length: 278  Bit Score: 67.78  E-value: 8.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  25 KKTREE--KLR----NISREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEETnGNVTTVELSSERVGEALANFE 98
Cdd:PLN02476   86 RQLREEtsKMRgsqmQVSPDQAQLLAMLVQILGAERCIEVGVYTGYSSLAVALVLPES-GCLVACERDSNSLEVAKRYYE 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  99 NANLLQRIDVHNQEAGAFLDSQL----DHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSHAN---------- 164
Cdd:PLN02476  165 LAGVSHKVNVKHGLAAESLKSMIqngeGSSYDFAFVDADKRMYQDYFELLLQLVRVGGVIVMDNVLWHGRvadplvndak 244

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1193849578 165 --ELAEFIKMIEEDKMFETVLLAFQNGAFVARKK 196
Cdd:PLN02476  245 tiSIRNFNKKLMDDKRVSISMVPIGDGMTICRKR 278
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 53-183 6.23e-11

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 59.40  E-value: 6.23e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  53 KNILEIGTSNGYSTLWLADAVEETnGNVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAFLDsqlDHSFDFIFLDs 132
Cdd:COG2519    93 ARVLEAGTGSGALTLALARAVGPE-GKVYSYERREDFAEIARKNLERFGLPDNVELKLGDIREGID---EGDVDAVFLD- 167

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578 133 ertqyM---W-WLEHIKRILQPKGLLVVDNATshANELAEFIKMIEEDK-----MFETVL 183
Cdd:COG2519   168 -----MpdpWeALEAVAKALKPGGVLVAYVPT--VNQVSKLVEALRESGftdieAVETLL 220
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 55-152 2.08e-09

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 52.57  E-value: 2.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  55 ILEIGTSNGYSTLWLADAVeetNGNVTTVELSSERVGEALANFENANLlqRIDVHNQEAGAFldSQLDHSFDFIFLdSER 134
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRG---GARVTGVDLSPEMLERARERAAEAGL--NVEFVQGDAEDL--PFPDGSFDLVVS-SGV 72

                          90       100
                  ....*....|....*....|....
gi 1193849578 135 TQYMWW------LEHIKRILQPKG 152
Cdd:pfam13649  73 LHHLPDpdleaaLREIARVLKPGG 96
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 54-157 3.20e-09

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 54.15  E-value: 3.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  54 NILEIGTSNGYSTLWLADAveeTNGNVTTVELSSERVGEALANFENANlLQRIDVHNQEAGAFLDSQLDHsFDFIFLD-- 131
Cdd:COG0500    29 RVLDLGCGTGRNLLALAAR---FGGRVIGIDLSPEAIALARARAAKAG-LGNVEFLVADLAELDPLPAES-FDLVVAFgv 103

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1193849578 132 ------SERTQYmwwLEHIKRILQPKGLLVVD 157
Cdd:COG0500   104 lhhlppEEREAL---LRELARALKPGGVLLLS 132
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 55-156 5.16e-09

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 53.01  E-value: 5.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  55 ILEIGTSNGYSTLWLAdavEETNGNVTTVELSSERVGEALANFENANLLQRIDVHNQEagaFLDSQLDHSFDFIFL---- 130
Cdd:COG2230    55 VLDIGCGWGGLALYLA---RRYGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLAD---YRDLPADGQFDAIVSigmf 128

                          90       100       110
                  ....*....|....*....|....*....|
gi 1193849578 131 ----DSERTQYmwwLEHIKRILQPKGLLVV 156
Cdd:COG2230   129 ehvgPENYPAY---FAKVARLLKPGGRLLL 155
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 54-156 9.54e-09

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 50.89  E-value: 9.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  54 NILEIGTSNGYSTLWLADAVeetNGNVTTVELSSERVGEALANfENANLLQRIDVHNQEAGAFLDsQLDHSFDFIFLDSE 133
Cdd:cd02440     1 RVLDLGCGTGALALALASGP---GARVTGVDISPVALELARKA-AAALLADNVEVLKGDAEELPP-EADESFDVIISDPP 75

                          90       100       110
                  ....*....|....*....|....*....|
gi 1193849578 134 rtqYMWWLEHIKRILQ-------PKGLLVV 156
Cdd:cd02440    76 ---LHHLVEDLARFLEearrllkPGGVLVL 102
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 53-175 1.32e-08

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 51.53  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  53 KNILEIGTSNGYSTLWLADAveetNGNVTTVELSSERVGEALANFENANLlqRIDVHNQEAGAF-LDsqlDHSFDFIFL- 130
Cdd:COG2226    24 ARVLDLGCGTGRLALALAER----GARVTGVDISPEMLELARERAAEAGL--NVEFVVGDAEDLpFP---DGSFDLVISs 94

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1193849578 131 -------DSERTqymwwLEHIKRILQPKGLLVVdnATSHANELAEFIKMIEE 175
Cdd:COG2226    95 fvlhhlpDPERA-----LAEIARVLKPGGRLVV--VDFSPPDLAELEELLAE 139
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 53-156 5.41e-07

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 46.55  E-value: 5.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  53 KNILEIGTSNGYSTLWLADAVEEtngnVTTVELSSERVGEALANFENANllqrIDVHNQEAGAFldSQLDHSFDFIFL-- 130
Cdd:COG2227    26 GRVLDVGCGTGRLALALARRGAD----VTGVDISPEALEIARERAAELN----VDFVQGDLEDL--PLEDGSFDLVICse 95

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1193849578 131 ------DSERtqymwWLEHIKRILQPKGLLVV 156
Cdd:COG2227    96 vlehlpDPAA-----LLRELARLLKPGGLLLL 122
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 51-179 8.51e-07

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 47.83  E-value: 8.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  51 SAKNILEIGTSNGYSTLWLADAVEetNGNVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDHSFDFIF- 129
Cdd:COG4123    37 KGGRVLDLGTGTGVIALMLAQRSP--GARITGVEIQPEAAELARRNVALNGLEDRITVIHGDLKEFAAELPPGSFDLVVs 114

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1193849578 130 -------------LDSERTQYMW--------WLEHIKRILQPKGLLVVdnaTSHANELAEFIKMIEEDKMF 179
Cdd:COG4123   115 nppyfkagsgrksPDEARAIARHedaltledLIRAAARLLKPGGRFAL---IHPAERLAEILAALRKYGLG 182
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 56-156 9.91e-06

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 42.65  E-value: 9.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  56 LEIGTSNGYSTLWLADAVEetngNVTTVELSSERVGEALANFENANLLQRIdvhnqeaGAFLDSQL-DHSFDFIFLdser 134
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGA----RVTGVDISPEMLELAREKAPREGLTFVV-------GDAEDLPFpDNSFDLVLS---- 65

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1193849578 135 tqyMWWLEH----------IKRILQPKGLLVV 156
Cdd:pfam08241  66 ---SEVLHHvedperalreIARVLKPGGILII 94
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 51-176 1.34e-04

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 40.48  E-value: 1.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  51 SAKNILEIGTSNGYSTLWLADAVEEtNGNVTTVELSSERVGEALANFENaNLLQRIDVHNQEAGAFLDSQLDHSFDFIFL 130
Cdd:pfam13847   3 KGMRVLDLGCGTGHLSFELAEELGP-NAEVVGIDISEEAIEKARENAQK-LGFDNVEFEQGDIEELPELLEDDKFDVVIS 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1193849578 131 --------DSERTqymwwLEHIKRILQPKGLLVVdnatSHANELAEFIKMIEED 176
Cdd:pfam13847  81 ncvlnhipDPDKV-----LQEILRVLKPGGRLII----SDPDSLAELPAHVKED 125
RsmD COG0742
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 80-156 2.84e-04

16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA G966 N2-methylase RsmD is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440505 [Multi-domain]  Cd Length: 183  Bit Score: 40.06  E-value: 2.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  80 VTTVELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLD-------SERTqymwwLEHI--KRILQP 150
Cdd:COG0742    67 VVFVEKDRKAAAVIRKNLEKLGLEDRARVIRGDALRFLKRLAGEPFDLVFLDppyakglLEKA-----LELLaeNGLLAP 141


                  ....*.
gi 1193849578 151 KGLLVV 156
Cdd:COG0742   142 GGLIVV 147
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 52-158 4.84e-03

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 36.41  E-value: 4.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  52 AKNILEIGTSNGYSTLWLADAVEETngNVTTVELSSERVGEALANFEnANLLQRIDVHnqeAGAFLDSQLDHSFDFI--- 128
Cdd:pfam05175  32 SGKVLDLGCGAGVLGAALAKESPDA--ELTMVDINARALESARENLA-ANGLENGEVV---ASDVYSGVEDGKFDLIisn 105

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1193849578 129 --FLDSERTQYM-WW--LEHIKRILQPKG-LLVVDN 158
Cdd:pfam05175 106 ppFHAGLATTYNvAQrfIADAKRHLRPGGeLWIVAN 141
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
51-196 6.80e-03

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 35.74  E-value: 6.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1193849578  51 SAKNILEIGTSNGYSTLWLADAVEEtngnVTTVELSSERVGEALANFenanllQRIDVHNQEAGAFldSQLDHSFDFIFL 130
Cdd:COG4976    46 PFGRVLDLGCGTGLLGEALRPRGYR----LTGVDLSEEMLAKAREKG------VYDRLLVADLADL--AEPDGRFDLIVA 113

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1193849578 131 --------DSERTqymwwLEHIKRILQPKGLLVVDNATSHAN-----ELAEFIKMIEEDKMFETVLLafqngaFVARKK 196
Cdd:COG4976   114 advltylgDLAAV-----FAGVARALKPGGLFIFSVEDADGSgryahSLDYVRDLLAAAGFEVPGLL------VVARKP 181
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 54-104 8.67e-03

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 35.76  E-value: 8.67e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1193849578  54 NILEIGTSNGYSTLWLADAVEETnGNVTTVelssERVGEaLANFENANLLQ 104
Cdd:PRK13942   79 KVLEIGTGSGYHAAVVAEIVGKS-GKVVTI----ERIPE-LAEKAKKTLKK 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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