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Conserved domains on  [gi|61248670|sp|P0A3V2|]
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RecName: Full=Tryptophan 2-monooxygenase

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 12029847)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to flavin-containing L-amino-acid oxidase that catalyzes the oxidative deamination of predominantly hydrophobic and aromatic L-amino acids

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 246-729 6.13e-104

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


:

Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 325.98  E-value: 6.13e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   246 ISGLVVANELLHAGvDDVTIYEASDRVGGKLWSHAFRDapsVVAEMGAMRFPPAAFCLFFFLERYGLSSMRPFPNPGTVD 325
Cdd:pfam01593   1 LAGLAAARELLRAG-HDVTVLEARDRVGGRIRTVRDDG---FLIELGAMWFHGAQPPLLALLKELGLEDRLVLPDPAPFY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   326 TYLVYQGVQYmwkagqlpPKLFHRVYNGWRAFLKDGFyerdivlasPVAITQALKSGDIRWAHDSWqiwlNRFGRESFSS 405
Cdd:pfam01593  77 TVLFAGGRRY--------PGDFRRVPAGWEGLLEFGR---------LLSIPEKLRLGLAALASDAL----DEFDLDDFSL 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   406 GIERIFLGTHPPGG-ETWSFPHDWDLFKLMGIGSGGFG---PVFESGFIEILRLVINGYEENQRMCPEGISELPRRIASE 481
Cdd:pfam01593 136 AESLLFLGRRGPGDvEVWDRLIDPELFAALPFASGAFAgdpSELSAGLALPLLWALLGEGGSLLLPRGGLGALPDALAAQ 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   482 VVnGVSVSQRIChvqVRAIQKEKTKIKIRLKSGISELYDKVVVTSGLANIQlRHCLTCDtniFQAPVNQAVDNSHMTGSS 561
Cdd:pfam01593 216 LL-GGDVRLNTR---VRSIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLK-RILFTPP---LPPEKARAIRNLGYGPVN 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   562 KLFLMTERKFWLDHIL--PSCVLMDGIAKAVYCLDYEPQDPNGKGLVLISYTWEDDSHKLLAVPDKKERLCLLRDAISRs 639
Cdd:pfam01593 288 KVHLEFDRKFWPDLGLlgLLSELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVGPGDRARELEGLSDEELLQAVLRDLRK- 366

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   640 fpafaqhLFPACADYDQNVIQHDWLTDENAGGAFKLNRRGedfySEELFFQALDTANDTGVYLAGCSCS--FTGGwVEGA 717
Cdd:pfam01593 367 -------LFGEEAPEPLRVLVSDWHTDPWPRGSYSLPQYG----PGHDDYRPLARTPDPGLFFAGEHTStgYPGT-VEGA 434

                         490
                  ....*....|..
gi 61248670   718 NRTPCNAVCAII 729
Cdd:pfam01593 435 IESGRRAARAVL 446
RolB_RolC pfam02027
RolB/RolC glucosidase family; This family of proteins includes RolB and RolC. RolC releases ...
 11-195 2.61e-41

RolB/RolC glucosidase family; This family of proteins includes RolB and RolC. RolC releases cytokinins from glucoside conjugates. Whereas RolB hydrolyses indole glucosides.


:

Pssm-ID: 366884  Cd Length: 184  Bit Score: 149.13  E-value: 2.61e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670    11 CDHLPTKMVDLTMVDKADELDRRVSDAFLEREASRGRRITQISTECSAGLACKR-LADGRFPEISAGGKVAVLSA--YIY 87
Cdd:pfam02027   1 MTRPVFTVIDLSNITDREELKLRLEQARSDYRAFVERDLLFAQRSWVARFLRKPcLDGPRLPGIFDGDTILLDDSplYVY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670    88 IGKEILGRILESKPWARATVSGLVAIDLAPFCMDFSEAQLIQALFLLS-GKRCAPIDLSHFVAISISKTAgfrTLPMPLY 166
Cdd:pfam02027  81 CSREILRQCAESRPLSSSSPSGLVATTLPPYREDITREQMRQLLNLVSvGYYQGPHDLSHFVAILPSKSF---RRKGAFH 157

                         170       180       190
                  ....*....|....*....|....*....|
gi 61248670   167 ENGTmkcVTGFTITLEG-AVPFDMVAYGRN 195
Cdd:pfam02027 158 TSGE---VYGFFARSLGdAFPYDIVAVGRA 184
 
Name Accession Description Interval E-value
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 246-729 6.13e-104

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 325.98  E-value: 6.13e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   246 ISGLVVANELLHAGvDDVTIYEASDRVGGKLWSHAFRDapsVVAEMGAMRFPPAAFCLFFFLERYGLSSMRPFPNPGTVD 325
Cdd:pfam01593   1 LAGLAAARELLRAG-HDVTVLEARDRVGGRIRTVRDDG---FLIELGAMWFHGAQPPLLALLKELGLEDRLVLPDPAPFY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   326 TYLVYQGVQYmwkagqlpPKLFHRVYNGWRAFLKDGFyerdivlasPVAITQALKSGDIRWAHDSWqiwlNRFGRESFSS 405
Cdd:pfam01593  77 TVLFAGGRRY--------PGDFRRVPAGWEGLLEFGR---------LLSIPEKLRLGLAALASDAL----DEFDLDDFSL 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   406 GIERIFLGTHPPGG-ETWSFPHDWDLFKLMGIGSGGFG---PVFESGFIEILRLVINGYEENQRMCPEGISELPRRIASE 481
Cdd:pfam01593 136 AESLLFLGRRGPGDvEVWDRLIDPELFAALPFASGAFAgdpSELSAGLALPLLWALLGEGGSLLLPRGGLGALPDALAAQ 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   482 VVnGVSVSQRIChvqVRAIQKEKTKIKIRLKSGISELYDKVVVTSGLANIQlRHCLTCDtniFQAPVNQAVDNSHMTGSS 561
Cdd:pfam01593 216 LL-GGDVRLNTR---VRSIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLK-RILFTPP---LPPEKARAIRNLGYGPVN 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   562 KLFLMTERKFWLDHIL--PSCVLMDGIAKAVYCLDYEPQDPNGKGLVLISYTWEDDSHKLLAVPDKKERLCLLRDAISRs 639
Cdd:pfam01593 288 KVHLEFDRKFWPDLGLlgLLSELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVGPGDRARELEGLSDEELLQAVLRDLRK- 366

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   640 fpafaqhLFPACADYDQNVIQHDWLTDENAGGAFKLNRRGedfySEELFFQALDTANDTGVYLAGCSCS--FTGGwVEGA 717
Cdd:pfam01593 367 -------LFGEEAPEPLRVLVSDWHTDPWPRGSYSLPQYG----PGHDDYRPLARTPDPGLFFAGEHTStgYPGT-VEGA 434

                         490
                  ....*....|..
gi 61248670   718 NRTPCNAVCAII 729
Cdd:pfam01593 435 IESGRRAARAVL 446
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
235-734 1.70e-65

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 224.03  E-value: 1.70e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 235 PKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKLWSHAFrDAPSVVAEMGAMRFPPAAFCLFFFLERYGLsS 314
Cdd:COG1231   6 RGKDVVIVGAGLAGLAAARELRKAGL-DVTVLEARDRVGGRVWTLRF-GDDGLYAELGAMRIPPSHTNLLALARELGL-P 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 315 MRPFPNpGTVDTYLVYQGVQYMWKAGQLppkLFHRVYNGWRAFLKDgfyerdivlaspvaITQALksgdirwahDSWQIW 394
Cdd:COG1231  83 LEPFPN-ENGNALLYLGGKRVRAGEIAA---DLRGVAELLAKLLRA--------------LAAAL---------DPWAHP 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 395 LNRFGRESFSSgieriFLGTHPpggetwSFPHDWDLFKLMGIGSGGfGPVFESGFIEILRLV-INGYEENQRMCPEGISE 473
Cdd:COG1231 136 AAELDRESLAE-----WLRRNG------ASPSARRLLGLLGAGEYG-ADPDELSLLDLLRYAaSAGGGAQQFRIVGGMDQ 203

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 474 LPRRIASEVVNGVSVSQRichvqVRAIQKEKTKIKIRLKSGISELYDKVVVT---SGLANIQLrhcltcdTNIFQAPVNQ 550
Cdd:COG1231 204 LPRALAAELGDRIRLGAP-----VTRIRQDGDGVTVTTDDGGTVRADAVIVTvppSVLRRIEF-------DPPLPAAKRA 271

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 551 AVDNSHMTGSSKLFLMTERKFWL-DHILPSCVLMDGIAKAVYCLDYEPQDPNGkglVLISYTWEDDSHKLLAVPDkKERL 629
Cdd:COG1231 272 AIQRLPYGAAIKVFLQFDRPFWEeDGLYGGISLTDLPIRQTWYPSNGPDGGAG---VLLGYVGGDDARALAALSP-EERV 347

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 630 CLLRDAISRSFPAFAQHLfpacadydQNVIQHDWLTDENAGGAFKLNRRGEDFYseelFFQALdTANDTGVYLAGCSCSF 709
Cdd:COG1231 348 AAALEQLARIFGVYAAEP--------VDYVSTDWGRDPWSRGAYAAAPPGQLTA----AGPAL-AEPDGRIHFAGEHTSD 414

                       490       500
                ....*....|....*....|....*.
gi 61248670 710 TG-GWVEGANRTPCNAVCAIIHNCGG 734
Cdd:COG1231 415 EWpGWVEGALESGERAAAEILARLGG 440
RolB_RolC pfam02027
RolB/RolC glucosidase family; This family of proteins includes RolB and RolC. RolC releases ...
 11-195 2.61e-41

RolB/RolC glucosidase family; This family of proteins includes RolB and RolC. RolC releases cytokinins from glucoside conjugates. Whereas RolB hydrolyses indole glucosides.


Pssm-ID: 366884  Cd Length: 184  Bit Score: 149.13  E-value: 2.61e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670    11 CDHLPTKMVDLTMVDKADELDRRVSDAFLEREASRGRRITQISTECSAGLACKR-LADGRFPEISAGGKVAVLSA--YIY 87
Cdd:pfam02027   1 MTRPVFTVIDLSNITDREELKLRLEQARSDYRAFVERDLLFAQRSWVARFLRKPcLDGPRLPGIFDGDTILLDDSplYVY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670    88 IGKEILGRILESKPWARATVSGLVAIDLAPFCMDFSEAQLIQALFLLS-GKRCAPIDLSHFVAISISKTAgfrTLPMPLY 166
Cdd:pfam02027  81 CSREILRQCAESRPLSSSSPSGLVATTLPPYREDITREQMRQLLNLVSvGYYQGPHDLSHFVAILPSKSF---RRKGAFH 157

                         170       180       190
                  ....*....|....*....|....*....|
gi 61248670   167 ENGTmkcVTGFTITLEG-AVPFDMVAYGRN 195
Cdd:pfam02027 158 TSGE---VYGFFARSLGdAFPYDIVAVGRA 184
PLN02676 PLN02676
polyamine oxidase
 235-293 7.78e-10

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 62.04  E-value: 7.78e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 61248670  235 PKPKVAVIGAGISGLVVANELLHAGVDDVTIYEASDRVGGKLWSHAFRDapsVVAEMGA 293
Cdd:PLN02676  25 PSPSVIIVGAGMSGISAAKTLSEAGIEDILILEATDRIGGRMRKANFAG---VSVELGA 80
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 235-344 2.42e-06

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 50.60  E-value: 2.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   235 PKPKVAVIGAGISGLVVANEL--LHAGVD-DVTIYEASDRVGGKLWShafRDAPSVVAEMGAMRFPPAAFCLFFFLERYG 311
Cdd:TIGR00562   1 GKKHVVIIGGGISGLCAAYYLekEIPELPvELTLVEASDRVGGKIQT---VKEDGYLIERGPDSFLERKKSAPDLVKDLG 77

                          90       100       110
                  ....*....|....*....|....*....|...
gi 61248670   312 LSSMrpFPNPGTVDTYLvyqgvqyMWKAGQLPP 344
Cdd:TIGR00562  78 LEHV--LVSDATGQRYV-------LVNRGKLMP 101
 
Name Accession Description Interval E-value
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 246-729 6.13e-104

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 325.98  E-value: 6.13e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   246 ISGLVVANELLHAGvDDVTIYEASDRVGGKLWSHAFRDapsVVAEMGAMRFPPAAFCLFFFLERYGLSSMRPFPNPGTVD 325
Cdd:pfam01593   1 LAGLAAARELLRAG-HDVTVLEARDRVGGRIRTVRDDG---FLIELGAMWFHGAQPPLLALLKELGLEDRLVLPDPAPFY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   326 TYLVYQGVQYmwkagqlpPKLFHRVYNGWRAFLKDGFyerdivlasPVAITQALKSGDIRWAHDSWqiwlNRFGRESFSS 405
Cdd:pfam01593  77 TVLFAGGRRY--------PGDFRRVPAGWEGLLEFGR---------LLSIPEKLRLGLAALASDAL----DEFDLDDFSL 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   406 GIERIFLGTHPPGG-ETWSFPHDWDLFKLMGIGSGGFG---PVFESGFIEILRLVINGYEENQRMCPEGISELPRRIASE 481
Cdd:pfam01593 136 AESLLFLGRRGPGDvEVWDRLIDPELFAALPFASGAFAgdpSELSAGLALPLLWALLGEGGSLLLPRGGLGALPDALAAQ 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   482 VVnGVSVSQRIChvqVRAIQKEKTKIKIRLKSGISELYDKVVVTSGLANIQlRHCLTCDtniFQAPVNQAVDNSHMTGSS 561
Cdd:pfam01593 216 LL-GGDVRLNTR---VRSIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLK-RILFTPP---LPPEKARAIRNLGYGPVN 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   562 KLFLMTERKFWLDHIL--PSCVLMDGIAKAVYCLDYEPQDPNGKGLVLISYTWEDDSHKLLAVPDKKERLCLLRDAISRs 639
Cdd:pfam01593 288 KVHLEFDRKFWPDLGLlgLLSELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVGPGDRARELEGLSDEELLQAVLRDLRK- 366

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   640 fpafaqhLFPACADYDQNVIQHDWLTDENAGGAFKLNRRGedfySEELFFQALDTANDTGVYLAGCSCS--FTGGwVEGA 717
Cdd:pfam01593 367 -------LFGEEAPEPLRVLVSDWHTDPWPRGSYSLPQYG----PGHDDYRPLARTPDPGLFFAGEHTStgYPGT-VEGA 434

                         490
                  ....*....|..
gi 61248670   718 NRTPCNAVCAII 729
Cdd:pfam01593 435 IESGRRAARAVL 446
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
235-734 1.70e-65

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 224.03  E-value: 1.70e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 235 PKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKLWSHAFrDAPSVVAEMGAMRFPPAAFCLFFFLERYGLsS 314
Cdd:COG1231   6 RGKDVVIVGAGLAGLAAARELRKAGL-DVTVLEARDRVGGRVWTLRF-GDDGLYAELGAMRIPPSHTNLLALARELGL-P 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 315 MRPFPNpGTVDTYLVYQGVQYMWKAGQLppkLFHRVYNGWRAFLKDgfyerdivlaspvaITQALksgdirwahDSWQIW 394
Cdd:COG1231  83 LEPFPN-ENGNALLYLGGKRVRAGEIAA---DLRGVAELLAKLLRA--------------LAAAL---------DPWAHP 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 395 LNRFGRESFSSgieriFLGTHPpggetwSFPHDWDLFKLMGIGSGGfGPVFESGFIEILRLV-INGYEENQRMCPEGISE 473
Cdd:COG1231 136 AAELDRESLAE-----WLRRNG------ASPSARRLLGLLGAGEYG-ADPDELSLLDLLRYAaSAGGGAQQFRIVGGMDQ 203

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 474 LPRRIASEVVNGVSVSQRichvqVRAIQKEKTKIKIRLKSGISELYDKVVVT---SGLANIQLrhcltcdTNIFQAPVNQ 550
Cdd:COG1231 204 LPRALAAELGDRIRLGAP-----VTRIRQDGDGVTVTTDDGGTVRADAVIVTvppSVLRRIEF-------DPPLPAAKRA 271

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 551 AVDNSHMTGSSKLFLMTERKFWL-DHILPSCVLMDGIAKAVYCLDYEPQDPNGkglVLISYTWEDDSHKLLAVPDkKERL 629
Cdd:COG1231 272 AIQRLPYGAAIKVFLQFDRPFWEeDGLYGGISLTDLPIRQTWYPSNGPDGGAG---VLLGYVGGDDARALAALSP-EERV 347

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 630 CLLRDAISRSFPAFAQHLfpacadydQNVIQHDWLTDENAGGAFKLNRRGEDFYseelFFQALdTANDTGVYLAGCSCSF 709
Cdd:COG1231 348 AAALEQLARIFGVYAAEP--------VDYVSTDWGRDPWSRGAYAAAPPGQLTA----AGPAL-AEPDGRIHFAGEHTSD 414

                       490       500
                ....*....|....*....|....*.
gi 61248670 710 TG-GWVEGANRTPCNAVCAIIHNCGG 734
Cdd:COG1231 415 EWpGWVEGALESGERAAAEILARLGG 440
RolB_RolC pfam02027
RolB/RolC glucosidase family; This family of proteins includes RolB and RolC. RolC releases ...
 11-195 2.61e-41

RolB/RolC glucosidase family; This family of proteins includes RolB and RolC. RolC releases cytokinins from glucoside conjugates. Whereas RolB hydrolyses indole glucosides.


Pssm-ID: 366884  Cd Length: 184  Bit Score: 149.13  E-value: 2.61e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670    11 CDHLPTKMVDLTMVDKADELDRRVSDAFLEREASRGRRITQISTECSAGLACKR-LADGRFPEISAGGKVAVLSA--YIY 87
Cdd:pfam02027   1 MTRPVFTVIDLSNITDREELKLRLEQARSDYRAFVERDLLFAQRSWVARFLRKPcLDGPRLPGIFDGDTILLDDSplYVY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670    88 IGKEILGRILESKPWARATVSGLVAIDLAPFCMDFSEAQLIQALFLLS-GKRCAPIDLSHFVAISISKTAgfrTLPMPLY 166
Cdd:pfam02027  81 CSREILRQCAESRPLSSSSPSGLVATTLPPYREDITREQMRQLLNLVSvGYYQGPHDLSHFVAILPSKSF---RRKGAFH 157

                         170       180       190
                  ....*....|....*....|....*....|
gi 61248670   167 ENGTmkcVTGFTITLEG-AVPFDMVAYGRN 195
Cdd:pfam02027 158 TSGE---VYGFFARSLGdAFPYDIVAVGRA 184
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 236-525 6.04e-13

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 71.40  E-value: 6.04e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 236 KPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKLWSHAFRDapsVVAEMGAMRF---PPAAFCLfffLERYGL 312
Cdd:COG1232   1 MKRVAVIGGGIAGLTAAYRLAKAGH-EVTVLEASDRVGGLIRTVEVDG---FRIDRGPHSFltrDPEVLEL---LRELGL 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 313 SSMRPFPNPGTvdTYLVYQGVqymwkagqlppklFHRVYNGWRAFLKDGfyerdivLASPVAITQALKS---GDIRWAHD 389
Cdd:COG1232  74 GDELVWPNTRK--SYIYYGGK-------------LHPLPQGPLALLRSP-------LLSLAGKLRALLEllaPRRPPGED 131

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 390 -SWQIWL-NRFGRESFSSGIERIFLGTHppGGE------TWSFPHdwdlFKLMGIGSGgfgpvfeSGFIEILRLVINGYE 461
Cdd:COG1232 132 eSLAEFVrRRFGREVYERLVEPLLEGVY--AGDpdelsaDWAFPR----LKRLELEHG-------SLIKGALALRKGAKA 198

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 61248670 462 ENQRMCPE-GISELPRRIASEVVNGvsvsqRI-CHVQVRAIQKEKTKIKIRLKSGISELYDKVVVT 525
Cdd:COG1232 199 GEVFGYLRgGLGTLVEALAEALEAG-----EIrLGTRVTAIEREGGGWRVTTSDGETIEADAVVSA 259
PLN02676 PLN02676
polyamine oxidase
 235-293 7.78e-10

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 62.04  E-value: 7.78e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 61248670  235 PKPKVAVIGAGISGLVVANELLHAGVDDVTIYEASDRVGGKLWSHAFRDapsVVAEMGA 293
Cdd:PLN02676  25 PSPSVIIVGAGMSGISAAKTLSEAGIEDILILEATDRIGGRMRKANFAG---VSVELGA 80
PRK07233 PRK07233
hypothetical protein; Provisional
 238-274 5.59e-09

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 59.13  E-value: 5.59e-09
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 61248670  238 KVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGG 274
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRGH-EVTVFEADDQLGG 36
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
235-293 2.02e-08

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 56.81  E-value: 2.02e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 61248670 235 PKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKLwshAFRDAPSVVAEMGA 293
Cdd:COG3380   2 SMPDIAIIGAGIAGLAAARALQDAGH-EVTVFEKSRGVGGRM---ATRRLDGGRFDHGA 56
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 237-276 2.03e-08

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 57.17  E-value: 2.03e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 61248670  237 PKVAVIGAGISGLVVANELLHAGVD-DVTIYEASDRVGGKL 276
Cdd:PRK11883   1 KKVAIIGGGITGLSAAYRLHKKGPDaDITLLEASDRLGGKI 41
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 236-276 6.56e-08

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 55.63  E-value: 6.56e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 61248670 236 KPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKL 276
Cdd:COG1233   3 MYDVVVIGAGIGGLAAAALLARAGY-RVTVLEKNDTPGGRA 42
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 219-276 8.22e-08

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 55.14  E-value: 8.22e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 61248670 219 DQCSDSGRIGFFPEDVP-KPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKL 276
Cdd:COG0493 103 DKAFEEGWVKPPPPAPRtGKKVAVVGSGPAGLAAAYQLARAGH-EVTVFEALDKPGGLL 160
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
235-280 8.69e-08

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 55.12  E-value: 8.69e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 61248670 235 PKPKVAVIGAGISGLVVAnELLHaGVDDVTIYEASDRVGGklwsHA 280
Cdd:COG2907   2 ARMRIAVIGSGISGLTAA-WLLS-RRHDVTLFEANDRLGG----HT 41
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 238-274 1.71e-07

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 54.41  E-value: 1.71e-07
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 61248670  238 KVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGG 274
Cdd:PRK11749 142 KVAVIGAGPAGLTAAHRLARKGY-DVTIFEARDKAGG 177
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 235-275 2.13e-07

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 54.09  E-value: 2.13e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 61248670 235 PKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGK 275
Cdd:COG3349   2 MPPRVVVVGGGLAGLAAAVELAEAGF-RVTLLEARPRLGGR 41
PLN02487 PLN02487
zeta-carotene desaturase
 235-311 2.23e-07

zeta-carotene desaturase


Pssm-ID: 215268 [Multi-domain]  Cd Length: 569  Bit Score: 54.42  E-value: 2.23e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 61248670  235 PKPKVAVIGAGISGLVVANELLHAGvDDVTIYEASDRVGGKLWShaFRDAPSVVAEMGAMRFPPAAFCLFFFLERYG 311
Cdd:PLN02487  74 PKLKVAIIGAGLAGMSTAVELLDQG-HEVDIYESRPFIGGKVGS--FVDKNGNHIEMGLHVFFGCYNNLFRLMKKVG 147
PLN02576 PLN02576
protoporphyrinogen oxidase
 239-278 2.68e-07

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 53.86  E-value: 2.68e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 61248670  239 VAVIGAGISGLVVANELLHAGVDDVTIYEASDRVGGKLWS 278
Cdd:PLN02576  15 VAVVGAGVSGLAAAYALASKHGVNVLVTEARDRVGGNITS 54
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 231-274 3.19e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 53.33  E-value: 3.19e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 61248670 231 PEDVPKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGG 274
Cdd:COG2072   1 TAATEHVDVVVIGAGQAGLAAAYHLRRAGI-DFVVLEKADDVGG 43
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 238-276 4.48e-07

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 53.24  E-value: 4.48e-07
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 61248670  238 KVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKL 276
Cdd:PRK12810 145 KVAVVGSGPAGLAAADQLARAGH-KVTVFERADRIGGLL 182
PRK07208 PRK07208
hypothetical protein; Provisional
 235-274 1.36e-06

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 51.43  E-value: 1.36e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 61248670  235 PKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGG 274
Cdd:PRK07208   3 NKKSVVIIGAGPAGLTAAYELLKRGY-PVTVLEADPVVGG 41
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 235-344 2.42e-06

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 50.60  E-value: 2.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670   235 PKPKVAVIGAGISGLVVANEL--LHAGVD-DVTIYEASDRVGGKLWShafRDAPSVVAEMGAMRFPPAAFCLFFFLERYG 311
Cdd:TIGR00562   1 GKKHVVIIGGGISGLCAAYYLekEIPELPvELTLVEASDRVGGKIQT---VKEDGYLIERGPDSFLERKKSAPDLVKDLG 77

                          90       100       110
                  ....*....|....*....|....*....|...
gi 61248670   312 LSSMrpFPNPGTVDTYLvyqgvqyMWKAGQLPP 344
Cdd:TIGR00562  78 LEHV--LVSDATGQRYV-------LVNRGKLMP 101
PLN02568 PLN02568
polyamine oxidase
 236-293 2.65e-06

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 50.60  E-value: 2.65e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 61248670  236 KPKVAVIGAGISGLVVANELLHAGVD----DVTIYEASDRVGGKLWSHAFrdaPSVVAEMGA 293
Cdd:PLN02568   5 KPRIVIIGAGMAGLTAANKLYTSSAAndmfELTVVEGGDRIGGRINTSEF---GGERIEMGA 63
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
241-293 9.38e-06

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 43.67  E-value: 9.38e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 61248670   241 VIGAGISGLVVANELLHAGVdDVTIYEASDRVGGklWSHAFRDaPSVVAEMGA 293
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGF-RVLVLEKRDRLGG--NAYSYRV-PGYVFDYGA 49
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 235-284 3.36e-05

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 46.47  E-value: 3.36e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 61248670 235 PKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKLWSHAFRDA 284
Cdd:COG0654   2 MRTDVLIVGGGPAGLALALALARAGI-RVTVVERAPPPRPDGRGIALSPR 50
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 228-276 7.00e-05

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 46.26  E-value: 7.00e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 61248670  228 GFFPEDVPKP--KVAVIGAGISGLVVANELLHAGvDDVTIYEASDRVGGKL 276
Cdd:PRK12814 183 RYIPERAPKSgkKVAIIGAGPAGLTAAYYLLRKG-HDVTIFDANEQAGGMM 232
PRK12831 PRK12831
putative oxidoreductase; Provisional
 231-276 7.56e-05

putative oxidoreductase; Provisional


Pssm-ID: 183780 [Multi-domain]  Cd Length: 464  Bit Score: 45.78  E-value: 7.56e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 61248670  231 PEDVPKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKL 276
Cdd:PRK12831 135 TEEKKGKKVAVIGSGPAGLTCAGDLAKMGY-DVTIFEALHEPGGVL 179
PLN02268 PLN02268
probable polyamine oxidase
 237-276 1.35e-04

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 45.06  E-value: 1.35e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 61248670  237 PKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKL 276
Cdd:PLN02268   1 PSVIVIGGGIAGIAAARALHDASF-KVTLLESRDRIGGRV 39
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 238-286 1.52e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 44.70  E-value: 1.52e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 61248670   238 KVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVG-------GKLWSHAFRDAPS 286
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGL-SVTLLERGDDPGsgasgrnAGLIHPGLRYLEP 55
PRK12778 PRK12778
bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate ...
 230-276 2.71e-04

bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate synthase;


Pssm-ID: 237200 [Multi-domain]  Cd Length: 752  Bit Score: 44.35  E-value: 2.71e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 61248670  230 FPEDVPK--PKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKL 276
Cdd:PRK12778 423 VPEVAEKngKKVAVIGSGPAGLSFAGDLAKRGY-DVTVFEALHEIGGVL 470
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 229-274 2.87e-04

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 44.01  E-value: 2.87e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 61248670  229 FFPEDVPKpKVAVIGAGISGLvvanELLHA----GVDdVTIYEASDRVGG 274
Cdd:PRK06292 163 FELDKLPK-SLAVIGGGVIGL----ELGQAlsrlGVK-VTVFERGDRILP 206
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
238-312 3.29e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 43.74  E-value: 3.29e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61248670 238 KVAVIGAGISGLVVANELLHAGVdDVTIYE-------ASDRVGGKLWSHAFRDAPSVVAEMG--AMRFPPAafclffFLE 308
Cdd:COG0665   4 DVVVIGGGIAGLSTAYHLARRGL-DVTVLErgrpgsgASGRNAGQLRPGLAALADRALVRLAreALDLWRE------LAA 76


                ....
gi 61248670 309 RYGL 312
Cdd:COG0665  77 ELGI 80
PLN03000 PLN03000
amine oxidase
 230-278 5.90e-04

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 43.47  E-value: 5.90e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 61248670  230 FPEDVPKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKLWS 278
Cdd:PLN03000 178 FPAQSSKSSVVIVGAGLSGLAAARQLMRFGF-KVTVLEGRKRPGGRVYT 225
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 232-292 8.44e-04

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 42.67  E-value: 8.44e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 61248670  232 EDVPKPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKLWSHAFR-DAPSVVAEMG 292
Cdd:PLN02328 234 EGVEPANVVVVGAGLAGLVAARQLLSMGF-KVVVLEGRARPGGRVKTMKMKgDGVVAAADLG 294
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 238-273 9.23e-04

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 42.53  E-value: 9.23e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 61248670  238 KVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVG 273
Cdd:PRK01747 262 DAAIIGGGIAGAALALALARRGW-QVTLYEADEAPA 296
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 238-276 1.86e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 37.57  E-value: 1.86e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 61248670   238 KVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKL 276
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGS-KVTVVERRDRLLPGF 38
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
235-273 2.05e-03

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 41.48  E-value: 2.05e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 61248670 235 PKPKVAVIGAGISGLVVANELL-HAGVD-DVTIYEASDRVG 273
Cdd:COG4529   4 ARKRIAIIGGGASGTALAIHLLrRAPEPlRITLFEPRPELG 44
PLN02976 PLN02976
amine oxidase
 221-293 2.08e-03

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 41.78  E-value: 2.08e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 61248670   221 CSDSGRIGFFPED-VPKPKVAVIGAGISGLVVANELLHAGVDdVTIYEASDRVGGKLWSHafRDAPSVVAEMGA 293
Cdd:PLN02976  677 CIEMGGNHCVLCDsVDRKKIIVVGAGPAGLTAARHLQRQGFS-VTVLEARSRIGGRVYTD--RSSLSVPVDLGA 747
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
239-273 4.95e-03

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 40.13  E-value: 4.95e-03
                        10        20        30
                ....*....|....*....|....*....|....*
gi 61248670 239 VAVIGAGISGLVVANELLHAGVDDVTIYEASDRVG 273
Cdd:COG0579   7 VVIIGAGIVGLALARELSRYEDLKVLVLEKEDDVA 41
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
231-276 5.85e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 39.84  E-value: 5.85e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 61248670 231 PEDVP-KPKVAVIGAGISGLVVANELLHAGVdDVTIYEASDRVGGKL 276
Cdd:COG1148 134 PIKVPvNKRALVIGGGIAGMTAALELAEQGY-EVYLVEKEPELGGRA 179
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 239-277 8.58e-03

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 39.46  E-value: 8.58e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 61248670  239 VAVIGAGISGLVVANELLHAGvDDVTIYEASDRVGGkLW 277
Cdd:PLN02172  13 VAVIGAGAAGLVAARELRREG-HTVVVFEREKQVGG-LW 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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