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RecName: Full=ATP-dependent helicase/deoxyribonuclease subunit B; AltName: Full=ATP-dependent helicase/nuclease subunit AddB
Protein Classification
helicase-exonuclease AddAB subunit AddB ( domain architecture ID 11494978 )
helicase-exonuclease AddAB subunit AddB is part of a heterodimer that acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease
List of domain hits
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1163
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1905.62
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1 MG AE F LV GRSG S GKT KL IIN S I QDELR R A PFGKPII F LVPDQMTF L MEY E L AKTPDMG GM I RAQV F SFSRLAWRVLQ H TG 80
Cdd:TIGR02773 1 MG LR F IY GRSG T GKT TF IIN E I KQKIK R N PFGKPII L LVPDQMTF Q MEY A L LNDIELN GM L RAQV L SFSRLAWRVLQ E TG 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 81 G MS R P FLTSTG V QML L RKLIEEHK Q E F KVYQKAS D K S GFTAQ VER M L TEFKRY CLE PED I RRMAES G T A SEY rgerv L S E 160
Cdd:TIGR02773 81 G LT R T FLTSTG K QML I RKLIEEHK D E L KVYQKAS R K K GFTAQ LSE M I TEFKRY EVT PED L RRMAES I T D SEY ----- L K E 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 161 KL H DLSI L YQQ M E KS LADQYL H SEDYLTLLAE H IP LA EDIKGA H IY V DGF YQ FTPQE FR V L E Q LM VH A EHI T F SLT A DKP 240
Cdd:TIGR02773 156 KL E DLSI I YQQ F E ER LADQYL D SEDYLTLLAE K IP QS EDIKGA E IY I DGF HS FTPQE YS V I E A LM KK A KKV T V SLT L DKP 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 241 S y E REP H EL E LFR M T G KTYYRL H Q K AKEL NL D ITYKELSG TER H TK TP ELAHLE A Q YE ARPAI P YAEKQE A L TVM QA A NR 320
Cdd:TIGR02773 236 S - K REP D EL S LFR A T S KTYYRL K Q L AKEL GI D VEEPIFLN TER P TK NK ELAHLE K Q FD ARPAI A YAEKQE S L SIF QA N NR 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 321 RAE L EG I AREI HA LVR E KGYRYKD V AIL A R Q PEDYKD M VK E VF A DYEIPYFID G K A SMLNHPLIEFIRSSLDV LK GNWRY 400
Cdd:TIGR02773 315 RAE V EG V AREI LR LVR D KGYRYKD I AIL T R D PEDYKD L VK A VF S DYEIPYFID K K R SMLNHPLIEFIRSSLDV IQ GNWRY 394
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 401 EAVFR CV KT E LLFPLNEP KAK VRE QV DQLENY CI AYGIKG - D RW T K G D R FQYRRF VS LDDDFAQTD Q EIEM EN MLNDTRD 479
Cdd:TIGR02773 395 EAVFR YL KT G LLFPLNEP FID VRE LI DQLENY VL AYGIKG k K RW W K E D W FQYRRF RG LDDDFAQTD E EIEM QE MLNDTRD 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 480 WIVPPLF QLQ KRMKKAKTV Q E K AEALY RY LEE T D V P L KL DQ ERQRAEDDGRI I EA QQ H Q QAWDAVIQLL E EFVE MM G DD E 559
Cdd:TIGR02773 475 WIVPPLF TFE KRMKKAKTV K E F AEALY EF LEE L D L P D KL EK ERQRAEDDGRI E EA RE H E QAWDAVIQLL D EFVE VL G NE E 554
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 560 IS L D LFQ QM I EA G A E S L T FSLIPPALDQVFVG N MD L S R MY G T S C T F V LGANDGVLPARP D ENG V LSD D DRE W L KT IGVEL 639
Cdd:TIGR02773 555 MD L N LFQ EV I DI G L E Q L E FSLIPPALDQVFVG T MD R S K MY N T K C I F L LGANDGVLPARP K ENG I LSD E DRE L L EQ IGVEL 634
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 640 SS GG RE R LLDE H FL I Y M AF S S P SDRL Y VSYP I ADAEGK T L L PS M I VK RLEELFP HH KE R LL T NEPEQVSDEEQL M YV V NK 719
Cdd:TIGR02773 635 SS TS RE K LLDE Q FL V Y T AF T S A SDRL K VSYP L ADAEGK S L R PS I I IH RLEELFP KL KE S LL L NEPEQVSDEEQL S YV S NK 714
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 720 SVAQ S FTA SQLR L W T R E Y D ISDVWW ST YN VLMS E QDRL Q - SKKLF S S LF FR NE V KQL ER S VSR QLYGERIQ G SVSR M ET F 798
Cdd:TIGR02773 715 LPTL S ELT SQLR K W K R G Y P ISDVWW DV YN WYRE E DKWK Q g LEYVL S G LF YD NE T KQL QE S KAK QLYGERIQ A SVSR L ET Y 794
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 799 NACPF S HFA SH GL H LKER QFF KLEAPD I GQLFH SS LK L ISD R L R E Q KLDW R DLTKEQC E LF SY DAVE R LAPKLQ K EILLS 878
Cdd:TIGR02773 795 NACPF A HFA QY GL K LKER KIY KLEAPD L GQLFH EA LK E ISD E L K E E KLDW S DLTKEQC R LF AN DAVE N LAPKLQ H EILLS 874
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 879 SNR HY YV KE KL QK IVTR VS G I LSE H AK A SGFVP I GLELGFG - GK G PLPPL TF QLKNG CTM EL V GRIDRVDKAE SSKGLL L 957
Cdd:TIGR02773 875 SNR YR YV QK KL KR IVTR AV G V LSE Q AK R SGFVP V GLELGFG f GK N PLPPL KL QLKNG EEL EL R GRIDRVDKAE KEDETY L 954
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 958 RI V DYKSS D KGLDL A EVYYGLALQMLTYLD LSI T H SA D WLG MR ATPAGVLYFHIHDPMIQ SNLP L GLD EIEQEIFK KF KM 1037
Cdd:TIGR02773 955 RI I DYKSS S KGLDL T EVYYGLALQMLTYLD IVL T N SA K WLG NQ ATPAGVLYFHIHDPMIQ AKGD L TEE EIEQEIFK EY KM 1034
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1038 KGLLL G DQEVVRLMDTTL Q EG R SNII N A G LKKDGSL R S D S A A VG E K EF D LL T KHVRR T FQEAGE Q ITDGRVSIEPYKMK N 1117
Cdd:TIGR02773 1035 KGLLL S DQEVVRLMDTTL E EG S SNII P A S LKKDGSL G S R S K A AT E E EF E LL R KHVRR K FQEAGE N ITDGRVSIEPYKMK K 1114
1130 1140 1150 1160
....*....|....*....|....*....|....*....|....*.
gi 239938591 1118 K TPC T YC A F K SVCQFD E SLEENEYR P L K AEKD K TILEWI KK E AD GN 1163
Cdd:TIGR02773 1115 Q TPC Q YC N F S SVCQFD T SLEENEYR H L E AEKD E TILEWI NE E VG GN 1160
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1163
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1905.62
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1 MG AE F LV GRSG S GKT KL IIN S I QDELR R A PFGKPII F LVPDQMTF L MEY E L AKTPDMG GM I RAQV F SFSRLAWRVLQ H TG 80
Cdd:TIGR02773 1 MG LR F IY GRSG T GKT TF IIN E I KQKIK R N PFGKPII L LVPDQMTF Q MEY A L LNDIELN GM L RAQV L SFSRLAWRVLQ E TG 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 81 G MS R P FLTSTG V QML L RKLIEEHK Q E F KVYQKAS D K S GFTAQ VER M L TEFKRY CLE PED I RRMAES G T A SEY rgerv L S E 160
Cdd:TIGR02773 81 G LT R T FLTSTG K QML I RKLIEEHK D E L KVYQKAS R K K GFTAQ LSE M I TEFKRY EVT PED L RRMAES I T D SEY ----- L K E 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 161 KL H DLSI L YQQ M E KS LADQYL H SEDYLTLLAE H IP LA EDIKGA H IY V DGF YQ FTPQE FR V L E Q LM VH A EHI T F SLT A DKP 240
Cdd:TIGR02773 156 KL E DLSI I YQQ F E ER LADQYL D SEDYLTLLAE K IP QS EDIKGA E IY I DGF HS FTPQE YS V I E A LM KK A KKV T V SLT L DKP 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 241 S y E REP H EL E LFR M T G KTYYRL H Q K AKEL NL D ITYKELSG TER H TK TP ELAHLE A Q YE ARPAI P YAEKQE A L TVM QA A NR 320
Cdd:TIGR02773 236 S - K REP D EL S LFR A T S KTYYRL K Q L AKEL GI D VEEPIFLN TER P TK NK ELAHLE K Q FD ARPAI A YAEKQE S L SIF QA N NR 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 321 RAE L EG I AREI HA LVR E KGYRYKD V AIL A R Q PEDYKD M VK E VF A DYEIPYFID G K A SMLNHPLIEFIRSSLDV LK GNWRY 400
Cdd:TIGR02773 315 RAE V EG V AREI LR LVR D KGYRYKD I AIL T R D PEDYKD L VK A VF S DYEIPYFID K K R SMLNHPLIEFIRSSLDV IQ GNWRY 394
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 401 EAVFR CV KT E LLFPLNEP KAK VRE QV DQLENY CI AYGIKG - D RW T K G D R FQYRRF VS LDDDFAQTD Q EIEM EN MLNDTRD 479
Cdd:TIGR02773 395 EAVFR YL KT G LLFPLNEP FID VRE LI DQLENY VL AYGIKG k K RW W K E D W FQYRRF RG LDDDFAQTD E EIEM QE MLNDTRD 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 480 WIVPPLF QLQ KRMKKAKTV Q E K AEALY RY LEE T D V P L KL DQ ERQRAEDDGRI I EA QQ H Q QAWDAVIQLL E EFVE MM G DD E 559
Cdd:TIGR02773 475 WIVPPLF TFE KRMKKAKTV K E F AEALY EF LEE L D L P D KL EK ERQRAEDDGRI E EA RE H E QAWDAVIQLL D EFVE VL G NE E 554
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 560 IS L D LFQ QM I EA G A E S L T FSLIPPALDQVFVG N MD L S R MY G T S C T F V LGANDGVLPARP D ENG V LSD D DRE W L KT IGVEL 639
Cdd:TIGR02773 555 MD L N LFQ EV I DI G L E Q L E FSLIPPALDQVFVG T MD R S K MY N T K C I F L LGANDGVLPARP K ENG I LSD E DRE L L EQ IGVEL 634
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 640 SS GG RE R LLDE H FL I Y M AF S S P SDRL Y VSYP I ADAEGK T L L PS M I VK RLEELFP HH KE R LL T NEPEQVSDEEQL M YV V NK 719
Cdd:TIGR02773 635 SS TS RE K LLDE Q FL V Y T AF T S A SDRL K VSYP L ADAEGK S L R PS I I IH RLEELFP KL KE S LL L NEPEQVSDEEQL S YV S NK 714
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 720 SVAQ S FTA SQLR L W T R E Y D ISDVWW ST YN VLMS E QDRL Q - SKKLF S S LF FR NE V KQL ER S VSR QLYGERIQ G SVSR M ET F 798
Cdd:TIGR02773 715 LPTL S ELT SQLR K W K R G Y P ISDVWW DV YN WYRE E DKWK Q g LEYVL S G LF YD NE T KQL QE S KAK QLYGERIQ A SVSR L ET Y 794
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 799 NACPF S HFA SH GL H LKER QFF KLEAPD I GQLFH SS LK L ISD R L R E Q KLDW R DLTKEQC E LF SY DAVE R LAPKLQ K EILLS 878
Cdd:TIGR02773 795 NACPF A HFA QY GL K LKER KIY KLEAPD L GQLFH EA LK E ISD E L K E E KLDW S DLTKEQC R LF AN DAVE N LAPKLQ H EILLS 874
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 879 SNR HY YV KE KL QK IVTR VS G I LSE H AK A SGFVP I GLELGFG - GK G PLPPL TF QLKNG CTM EL V GRIDRVDKAE SSKGLL L 957
Cdd:TIGR02773 875 SNR YR YV QK KL KR IVTR AV G V LSE Q AK R SGFVP V GLELGFG f GK N PLPPL KL QLKNG EEL EL R GRIDRVDKAE KEDETY L 954
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 958 RI V DYKSS D KGLDL A EVYYGLALQMLTYLD LSI T H SA D WLG MR ATPAGVLYFHIHDPMIQ SNLP L GLD EIEQEIFK KF KM 1037
Cdd:TIGR02773 955 RI I DYKSS S KGLDL T EVYYGLALQMLTYLD IVL T N SA K WLG NQ ATPAGVLYFHIHDPMIQ AKGD L TEE EIEQEIFK EY KM 1034
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1038 KGLLL G DQEVVRLMDTTL Q EG R SNII N A G LKKDGSL R S D S A A VG E K EF D LL T KHVRR T FQEAGE Q ITDGRVSIEPYKMK N 1117
Cdd:TIGR02773 1035 KGLLL S DQEVVRLMDTTL E EG S SNII P A S LKKDGSL G S R S K A AT E E EF E LL R KHVRR K FQEAGE N ITDGRVSIEPYKMK K 1114
1130 1140 1150 1160
....*....|....*....|....*....|....*....|....*.
gi 239938591 1118 K TPC T YC A F K SVCQFD E SLEENEYR P L K AEKD K TILEWI KK E AD GN 1163
Cdd:TIGR02773 1115 Q TPC Q YC N F S SVCQFD T SLEENEYR H L E AEKD E TILEWI NE E VG GN 1160
AddB
COG3857 ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
4-1149
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 1186.47
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 4 E F LV GR S GSGKT KLIINS I QD EL RR apf GKPII F LVP D QMTF LM E YE L A K TPDM GG M IRAQV F SFSRLAWRVLQ H TGG MS 83
Cdd:COG3857 1 R F IL GR A GSGKT TYLLEE I KE EL KE --- GKPII L LVP E QMTF QA E RA L L K RLGL GG S IRAQV L SFSRLAWRVLQ E TGG AT 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 84 RP F L TST G VQ MLLRK LI EEHK Q E F KV YQK A S DK S GF TA Q VERML TE F KRY CLE PED IRRM AE S gtaseyrgerv L S EKL H 163
Cdd:COG3857 78 RP L L SDA G KR MLLRK IL EEHK D E L KV FAR A A DK P GF IE Q LAELI TE L KRY GIT PED LEEA AE L ----------- L K EKL R 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 164 DL SIL Y QQM E KS LA DQ Y LH SED Y L T LLAE HIPLA E DIK GA H IY V DGF YQ FTPQE FRV LE Q L MVH A EHI T FS LT A D kpsye 243
Cdd:COG3857 147 DL ALI Y EAY E EK LA GR Y ID SED L L R LLAE KLEKS E FLE GA E IY I DGF TD FTPQE LEL LE A L LKK A KEV T IT LT L D ----- 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 244 re P H EL E LF RM TG K TY Y RL HQK AKE LNLDITY K elsgterht K T PELAHLE AQYE A R P A ipy A E KQ E ALTVMQ AANRRAE 323
Cdd:COG3857 222 -- P D EL D LF SA TG E TY E RL LEL AKE NGVEVEF K --------- K S PELAHLE RNLF A Y P P --- E E EP E GIEIIE AANRRAE 287
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 324 L E GI AREI HA LVRE K GYRY K D V A ILA R QP E D Y KDMVKE VFA D Y E IPYFID G K ASMLN HPL I E F I R S S L DVLKG N W RYE A V 403
Cdd:COG3857 288 V E AV AREI RR LVRE E GYRY R D I A VVV R DL E A Y APLIER VFA E Y G IPYFID E K RPLSH HPL V E L I L S L L ELVRS N F RYE D V 367
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 404 FR CV KT E LL F PL N epkakv RE QV D Q LENY CI AYGI K G D RW TK gdrfqyrrf VS L DDDFAQ TD Q E I E MENM LN DT RD WIVP 483
Cdd:COG3857 368 FR LL KT G LL R PL S ------ RE EI D R LENY VL AYGI R G R RW LE --------- RY L EEEEEL TD E E E E DLER LN EL RD RLLE 432
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 484 PL FQ L QK R M KKAKTV Q E K AEALY RY LEE TD VP L KL DQE R Q r AE DD G RII EA QQ H Q QAW D A V I Q LL E E F VE MM GD DEI SL D 563
Cdd:COG3857 433 PL LP L RE R L KKAKTV R E W AEALY EF LEE LG VP E KL EEW R E - AE EA G DLE EA RE H E QAW N A L I E LL D E L VE VL GD EKL SL E 511
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 564 L F QQMI E A G A E S LTF S LIPP A LDQV F VG NM D LS R MYGTSCT FVLG A N D GV L PARP D E N G V LSD DD RE W L KTI G V EL SSGG 643
Cdd:COG3857 512 E F LRIL E S G L E E LTF G LIPP S LDQV Q VG GL D RA R GLDFKAV FVLG L N E GV F PARP R E D G L LSD EE RE R L NEL G L EL PPTS 591
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 644 RERLL D E H FL I Y M A FSSP S D RLY V SYP I AD A EGK T LLPS MIVK RL E ELFP HHK ER L L tnepeqvs D EE Q L M Y VVNK svaq 723
Cdd:COG3857 592 RERLL E E R FL F Y R A LTRA S E RLY L SYP L AD E EGK A LLPS PLID RL R ELFP ELE ER S L -------- L EE E L E Y IGTP ---- 659
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 724 SFTA S Q L RLWT R EYDISDV WW ST Y NV L mseqdrlqskklfsslffrnevkqlersvsrqlyger IQG SVSR M ET FN ACPF 803
Cdd:COG3857 660 ESAL S E L AAAL R QLELAPL WW DV Y KW L ------------------------------------- LKL SVSR L ET YA ACPF 702
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 804 SH F ASH GL H LKER QFFK L E APD I G Q LFH SS L KLISDR L R E QK LDW R DL TK E QC E LFSYD AVE R LAP K LQ KE ILLSS N R HY 883
Cdd:COG3857 703 QF F LRY GL K LKER EEYE L D APD R G T LFH AV L ERFYKE L K E EG LDW A DL SD E EL E ELLEE AVE E LAP E LQ NG ILLSS A R YR 782
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 884 Y VK E K L QKIVT R VSGI L S E H A KA SGF V P IG LEL G FG GK G P LPPL TFQ L K NG CTME L V GRIDR V D KA ES S k G LL LRI V DYK 963
Cdd:COG3857 783 Y LL E R L KRLLK R ARRW L E E E A RR SGF E P VA LEL S FG PE G G LPPL ELE L P NG RKIR L R GRIDR I D RL ES D - G RY LRI I DYK 861
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 964 S SD K GL DL AE VYYGLALQ MLT YLD LSITHSA dwl G MR A T PAG V LYFH IHD P MIQSNL PL gldeieqeif KK F KMKGLLL G 1043
Cdd:COG3857 862 S GS K KF DL DD VYYGLALQ LPL YLD AALENLE --- G KE A E PAG A LYFH LKN P KLKAKK PL ---------- KK L KMKGLLL D 928
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1044 D Q EV VRLMD ttlqegrsniinag LKKDGS LRS d S AAVG E K EF DL L TK HVR RTFQ EAGE Q I TD G RVS I E PY KM K NK T P C T Y 1123
Cdd:COG3857 929 D P EV LEIIP -------------- LKKDGS FKN - S KVLS E E EF EE L LD HVR ELLK EAGE E I LA G DFA I N PY RT K DR T A C Q Y 993
1130 1140
....*....|....*....|....*.
gi 239938591 1124 C AF KS V C Q FDESLE E NEYR P LK AEKD 1149
Cdd:COG3857 994 C PY KS I C R FDESLE G NEYR K LK KKEG 1019
PDDEXK_1
pfam12705 PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
791-1131
2.58e-40
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 149.61
E-value: 2.58e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 791 S V SR M ET FNA CP FSH F ASHG L H L K E R qf FK L E APD I G Q L F H SS L KLIS drlreqkl D W RD L TK E QC E LFSYDAV E R L A P K 870
Cdd:pfam12705 3 S P SR L ET YLT CP LRF F LRYL L G L R E D -- EE L D APD L G T L V H AA L ERFY -------- R W GR L PE E DL E ELLQALL E E L W P E 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 871 -- LQ K EIL lss N R HYYVKEK L QKIVT R VSGI L S E HAK A S - GF V P IGL ELGFGG K gplppltfqlkngc T ME LVGRIDRVD 947
Cdd:pfam12705 73 lg LQ S EIL --- P R LPWLAGR L RRRLE R MLRR L A E WLR A R r GF R P VAV ELGFGG T -------------- T VR LVGRIDRVD 135
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 948 KAESSK gll LRI V DYK SS --- DKGL DL a EV Y Y G la LQ M L T YL DL s ITHSADW LG mra T PAG V LY FHIH DP MI qsnlplgl 1024
Cdd:pfam12705 136 LDGEGY --- LRI I DYK TG sap PQSE DL - DL Y E G -- LQ L L L YL LA - LAAGEKA LG --- G PAG A LY LRLD DP LK -------- 197
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1025 deieqeifkkfkmkglll G D Q EVV RL M DT T lqegrsniinaglkkdgslrsdsaavg E K EFD L L TKHV R rtfq E AG E Q I T 1104
Cdd:pfam12705 198 ------------------ K D E EVV EP M VL T --------------------------- E D EFD A L LQEL R ---- E LA E E I L 228
330 340
....*....|....*....|....*..
gi 239938591 1105 D G RVSIE P Y K mknkt P C T YC AFK S V C Q 1131
Cdd:pfam12705 229 A G EFPAR P G K ----- K C R YC PYR S I C P 250
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1163
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1905.62
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1 MG AE F LV GRSG S GKT KL IIN S I QDELR R A PFGKPII F LVPDQMTF L MEY E L AKTPDMG GM I RAQV F SFSRLAWRVLQ H TG 80
Cdd:TIGR02773 1 MG LR F IY GRSG T GKT TF IIN E I KQKIK R N PFGKPII L LVPDQMTF Q MEY A L LNDIELN GM L RAQV L SFSRLAWRVLQ E TG 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 81 G MS R P FLTSTG V QML L RKLIEEHK Q E F KVYQKAS D K S GFTAQ VER M L TEFKRY CLE PED I RRMAES G T A SEY rgerv L S E 160
Cdd:TIGR02773 81 G LT R T FLTSTG K QML I RKLIEEHK D E L KVYQKAS R K K GFTAQ LSE M I TEFKRY EVT PED L RRMAES I T D SEY ----- L K E 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 161 KL H DLSI L YQQ M E KS LADQYL H SEDYLTLLAE H IP LA EDIKGA H IY V DGF YQ FTPQE FR V L E Q LM VH A EHI T F SLT A DKP 240
Cdd:TIGR02773 156 KL E DLSI I YQQ F E ER LADQYL D SEDYLTLLAE K IP QS EDIKGA E IY I DGF HS FTPQE YS V I E A LM KK A KKV T V SLT L DKP 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 241 S y E REP H EL E LFR M T G KTYYRL H Q K AKEL NL D ITYKELSG TER H TK TP ELAHLE A Q YE ARPAI P YAEKQE A L TVM QA A NR 320
Cdd:TIGR02773 236 S - K REP D EL S LFR A T S KTYYRL K Q L AKEL GI D VEEPIFLN TER P TK NK ELAHLE K Q FD ARPAI A YAEKQE S L SIF QA N NR 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 321 RAE L EG I AREI HA LVR E KGYRYKD V AIL A R Q PEDYKD M VK E VF A DYEIPYFID G K A SMLNHPLIEFIRSSLDV LK GNWRY 400
Cdd:TIGR02773 315 RAE V EG V AREI LR LVR D KGYRYKD I AIL T R D PEDYKD L VK A VF S DYEIPYFID K K R SMLNHPLIEFIRSSLDV IQ GNWRY 394
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 401 EAVFR CV KT E LLFPLNEP KAK VRE QV DQLENY CI AYGIKG - D RW T K G D R FQYRRF VS LDDDFAQTD Q EIEM EN MLNDTRD 479
Cdd:TIGR02773 395 EAVFR YL KT G LLFPLNEP FID VRE LI DQLENY VL AYGIKG k K RW W K E D W FQYRRF RG LDDDFAQTD E EIEM QE MLNDTRD 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 480 WIVPPLF QLQ KRMKKAKTV Q E K AEALY RY LEE T D V P L KL DQ ERQRAEDDGRI I EA QQ H Q QAWDAVIQLL E EFVE MM G DD E 559
Cdd:TIGR02773 475 WIVPPLF TFE KRMKKAKTV K E F AEALY EF LEE L D L P D KL EK ERQRAEDDGRI E EA RE H E QAWDAVIQLL D EFVE VL G NE E 554
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 560 IS L D LFQ QM I EA G A E S L T FSLIPPALDQVFVG N MD L S R MY G T S C T F V LGANDGVLPARP D ENG V LSD D DRE W L KT IGVEL 639
Cdd:TIGR02773 555 MD L N LFQ EV I DI G L E Q L E FSLIPPALDQVFVG T MD R S K MY N T K C I F L LGANDGVLPARP K ENG I LSD E DRE L L EQ IGVEL 634
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 640 SS GG RE R LLDE H FL I Y M AF S S P SDRL Y VSYP I ADAEGK T L L PS M I VK RLEELFP HH KE R LL T NEPEQVSDEEQL M YV V NK 719
Cdd:TIGR02773 635 SS TS RE K LLDE Q FL V Y T AF T S A SDRL K VSYP L ADAEGK S L R PS I I IH RLEELFP KL KE S LL L NEPEQVSDEEQL S YV S NK 714
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 720 SVAQ S FTA SQLR L W T R E Y D ISDVWW ST YN VLMS E QDRL Q - SKKLF S S LF FR NE V KQL ER S VSR QLYGERIQ G SVSR M ET F 798
Cdd:TIGR02773 715 LPTL S ELT SQLR K W K R G Y P ISDVWW DV YN WYRE E DKWK Q g LEYVL S G LF YD NE T KQL QE S KAK QLYGERIQ A SVSR L ET Y 794
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 799 NACPF S HFA SH GL H LKER QFF KLEAPD I GQLFH SS LK L ISD R L R E Q KLDW R DLTKEQC E LF SY DAVE R LAPKLQ K EILLS 878
Cdd:TIGR02773 795 NACPF A HFA QY GL K LKER KIY KLEAPD L GQLFH EA LK E ISD E L K E E KLDW S DLTKEQC R LF AN DAVE N LAPKLQ H EILLS 874
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 879 SNR HY YV KE KL QK IVTR VS G I LSE H AK A SGFVP I GLELGFG - GK G PLPPL TF QLKNG CTM EL V GRIDRVDKAE SSKGLL L 957
Cdd:TIGR02773 875 SNR YR YV QK KL KR IVTR AV G V LSE Q AK R SGFVP V GLELGFG f GK N PLPPL KL QLKNG EEL EL R GRIDRVDKAE KEDETY L 954
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 958 RI V DYKSS D KGLDL A EVYYGLALQMLTYLD LSI T H SA D WLG MR ATPAGVLYFHIHDPMIQ SNLP L GLD EIEQEIFK KF KM 1037
Cdd:TIGR02773 955 RI I DYKSS S KGLDL T EVYYGLALQMLTYLD IVL T N SA K WLG NQ ATPAGVLYFHIHDPMIQ AKGD L TEE EIEQEIFK EY KM 1034
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1038 KGLLL G DQEVVRLMDTTL Q EG R SNII N A G LKKDGSL R S D S A A VG E K EF D LL T KHVRR T FQEAGE Q ITDGRVSIEPYKMK N 1117
Cdd:TIGR02773 1035 KGLLL S DQEVVRLMDTTL E EG S SNII P A S LKKDGSL G S R S K A AT E E EF E LL R KHVRR K FQEAGE N ITDGRVSIEPYKMK K 1114
1130 1140 1150 1160
....*....|....*....|....*....|....*....|....*.
gi 239938591 1118 K TPC T YC A F K SVCQFD E SLEENEYR P L K AEKD K TILEWI KK E AD GN 1163
Cdd:TIGR02773 1115 Q TPC Q YC N F S SVCQFD T SLEENEYR H L E AEKD E TILEWI NE E VG GN 1160
AddB
COG3857 ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
4-1149
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 1186.47
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 4 E F LV GR S GSGKT KLIINS I QD EL RR apf GKPII F LVP D QMTF LM E YE L A K TPDM GG M IRAQV F SFSRLAWRVLQ H TGG MS 83
Cdd:COG3857 1 R F IL GR A GSGKT TYLLEE I KE EL KE --- GKPII L LVP E QMTF QA E RA L L K RLGL GG S IRAQV L SFSRLAWRVLQ E TGG AT 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 84 RP F L TST G VQ MLLRK LI EEHK Q E F KV YQK A S DK S GF TA Q VERML TE F KRY CLE PED IRRM AE S gtaseyrgerv L S EKL H 163
Cdd:COG3857 78 RP L L SDA G KR MLLRK IL EEHK D E L KV FAR A A DK P GF IE Q LAELI TE L KRY GIT PED LEEA AE L ----------- L K EKL R 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 164 DL SIL Y QQM E KS LA DQ Y LH SED Y L T LLAE HIPLA E DIK GA H IY V DGF YQ FTPQE FRV LE Q L MVH A EHI T FS LT A D kpsye 243
Cdd:COG3857 147 DL ALI Y EAY E EK LA GR Y ID SED L L R LLAE KLEKS E FLE GA E IY I DGF TD FTPQE LEL LE A L LKK A KEV T IT LT L D ----- 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 244 re P H EL E LF RM TG K TY Y RL HQK AKE LNLDITY K elsgterht K T PELAHLE AQYE A R P A ipy A E KQ E ALTVMQ AANRRAE 323
Cdd:COG3857 222 -- P D EL D LF SA TG E TY E RL LEL AKE NGVEVEF K --------- K S PELAHLE RNLF A Y P P --- E E EP E GIEIIE AANRRAE 287
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 324 L E GI AREI HA LVRE K GYRY K D V A ILA R QP E D Y KDMVKE VFA D Y E IPYFID G K ASMLN HPL I E F I R S S L DVLKG N W RYE A V 403
Cdd:COG3857 288 V E AV AREI RR LVRE E GYRY R D I A VVV R DL E A Y APLIER VFA E Y G IPYFID E K RPLSH HPL V E L I L S L L ELVRS N F RYE D V 367
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 404 FR CV KT E LL F PL N epkakv RE QV D Q LENY CI AYGI K G D RW TK gdrfqyrrf VS L DDDFAQ TD Q E I E MENM LN DT RD WIVP 483
Cdd:COG3857 368 FR LL KT G LL R PL S ------ RE EI D R LENY VL AYGI R G R RW LE --------- RY L EEEEEL TD E E E E DLER LN EL RD RLLE 432
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 484 PL FQ L QK R M KKAKTV Q E K AEALY RY LEE TD VP L KL DQE R Q r AE DD G RII EA QQ H Q QAW D A V I Q LL E E F VE MM GD DEI SL D 563
Cdd:COG3857 433 PL LP L RE R L KKAKTV R E W AEALY EF LEE LG VP E KL EEW R E - AE EA G DLE EA RE H E QAW N A L I E LL D E L VE VL GD EKL SL E 511
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 564 L F QQMI E A G A E S LTF S LIPP A LDQV F VG NM D LS R MYGTSCT FVLG A N D GV L PARP D E N G V LSD DD RE W L KTI G V EL SSGG 643
Cdd:COG3857 512 E F LRIL E S G L E E LTF G LIPP S LDQV Q VG GL D RA R GLDFKAV FVLG L N E GV F PARP R E D G L LSD EE RE R L NEL G L EL PPTS 591
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 644 RERLL D E H FL I Y M A FSSP S D RLY V SYP I AD A EGK T LLPS MIVK RL E ELFP HHK ER L L tnepeqvs D EE Q L M Y VVNK svaq 723
Cdd:COG3857 592 RERLL E E R FL F Y R A LTRA S E RLY L SYP L AD E EGK A LLPS PLID RL R ELFP ELE ER S L -------- L EE E L E Y IGTP ---- 659
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 724 SFTA S Q L RLWT R EYDISDV WW ST Y NV L mseqdrlqskklfsslffrnevkqlersvsrqlyger IQG SVSR M ET FN ACPF 803
Cdd:COG3857 660 ESAL S E L AAAL R QLELAPL WW DV Y KW L ------------------------------------- LKL SVSR L ET YA ACPF 702
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 804 SH F ASH GL H LKER QFFK L E APD I G Q LFH SS L KLISDR L R E QK LDW R DL TK E QC E LFSYD AVE R LAP K LQ KE ILLSS N R HY 883
Cdd:COG3857 703 QF F LRY GL K LKER EEYE L D APD R G T LFH AV L ERFYKE L K E EG LDW A DL SD E EL E ELLEE AVE E LAP E LQ NG ILLSS A R YR 782
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 884 Y VK E K L QKIVT R VSGI L S E H A KA SGF V P IG LEL G FG GK G P LPPL TFQ L K NG CTME L V GRIDR V D KA ES S k G LL LRI V DYK 963
Cdd:COG3857 783 Y LL E R L KRLLK R ARRW L E E E A RR SGF E P VA LEL S FG PE G G LPPL ELE L P NG RKIR L R GRIDR I D RL ES D - G RY LRI I DYK 861
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 964 S SD K GL DL AE VYYGLALQ MLT YLD LSITHSA dwl G MR A T PAG V LYFH IHD P MIQSNL PL gldeieqeif KK F KMKGLLL G 1043
Cdd:COG3857 862 S GS K KF DL DD VYYGLALQ LPL YLD AALENLE --- G KE A E PAG A LYFH LKN P KLKAKK PL ---------- KK L KMKGLLL D 928
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1044 D Q EV VRLMD ttlqegrsniinag LKKDGS LRS d S AAVG E K EF DL L TK HVR RTFQ EAGE Q I TD G RVS I E PY KM K NK T P C T Y 1123
Cdd:COG3857 929 D P EV LEIIP -------------- LKKDGS FKN - S KVLS E E EF EE L LD HVR ELLK EAGE E I LA G DFA I N PY RT K DR T A C Q Y 993
1130 1140
....*....|....*....|....*.
gi 239938591 1124 C AF KS V C Q FDESLE E NEYR P LK AEKD 1149
Cdd:COG3857 994 C PY KS I C R FDESLE G NEYR K LK KKEG 1019
rexB_recomb
TIGR02774 ATP-dependent nuclease subunit B; DNA repair is accomplished by several different systems in ...
32-1119
1.23e-56
ATP-dependent nuclease subunit B; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RecAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. The partner may be designated AddB, as in Bacillus and in alphaproteobacteria, or RexB as in Streptococcus and Lactococcus. Note, however, that RexB proteins lack an N-terminal GxxGxGK[ST] ATP-binding motif found in Bacillus subtilis and related species, and this difference may be important; this model represents specifically RexB proteins as found in Streptococcus and Lactococcus. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274291 [Multi-domain]
Cd Length: 1076
Bit Score: 214.31
E-value: 1.23e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 32 GK PIIFLV P DQMT F LM E YELAKTPDMGGMIRAQ V FS F SRL A w R VLQHTGGMSRPF L TST G VQ M LL - R K L IEEHKQEF KVY 110
Cdd:TIGR02774 26 GK RVFYIA P NSLS F EK E RAVLEYLPQQASFSIT V TR F AQM A - R YFVLNDLPAKTT L DDI G LA M IF y R A L AQLEPGDL KVY 104
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 111 QKASDKSG F TA Q VERMLT E FKRYC L EPE D IRRMAES gtaseyrgervls E K LH DL SILYQQMEKS L ADQYLHSEDY L TLL 190
Cdd:TIGR02774 105 GRLKQDPQ F IQ Q LVELYK E LQKSQ L SIL D LENLTSP ------------- D K RE DL LAIFEKVTAY L NQGQYAQQSK L AHF 171
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 191 A E H I PLAE --- D I K GAHIYV DGF YQ F TPQ E FRVLEQ L MVHAEH I TFSLT A DKPS Y EREPH E LE L FRMTG K TYYR L H QK AK 267
Cdd:TIGR02774 172 I E A I ESGK lds D L K NTVLVI DGF TR F SAE E EALVSL L HGKGVE I IIGAY A SQKA Y KSSFS E GN L YQASV K FLHD L A QK YQ 251
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 268 ELNLD I TYK elsgter H TKTPELAH ---- LEA QYEARPAIPYAEKQ -- EA LT VMQAANRRA E L E GI AR E I HALVR E k GYR 341
Cdd:TIGR02774 252 TKAEF I SST ------- H ESKDSFDK lsrl LEA SHDFSELALDLDDK dk DN LT IWSCLTQKE E V E HV AR S I RQKLY E - GYR 323
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 342 YKD VAI L ARQPED Y KDMVKEV F AD Y E IP YFIDGKAS M LN HPL IE FI R S SLDVLKGNW R Y E A V FRCV KT E L LFPLNE pkak 421
Cdd:TIGR02774 324 YKD ILV L LGDVDS Y QLQLGKI F DQ Y D IP FYLGKAEP M AH HPL VQ FI E S LERIKRYRF R A E D V LNLL KT G L YGDFSQ ---- 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 422 vr EQV D QL E N Y CIAYG IKG drwtkgdrfqyrr FVSLDDD F AQTDQEIEMENM LN DT R DW I VP PL FQ L -- QKRMKKA K TVQ 499
Cdd:TIGR02774 400 -- SDI D AF E Q Y IRYAD IKG ------------- LPKFQKT F TKNHHGKFDLDR LN VL R QR I LA PL EE L fk SRKQLGE K LLN 464
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 500 E kaea LYRY L E E TDVPLK L dqer Q RAEDDGRII E AQQHQQA W DAVIQL LE E F VEMM G DDEI SLD L F QQMIEA G AESLTFS 579
Cdd:TIGR02774 465 K ---- FSVF L K E IALTKN L ---- Q DLATTLSEV E QEKQEEV W KTFTDI LE Q F ATIF G QEKL SLD D F LALLHS G MSLSQYR 536
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 580 LI P PAL D Q V F V GNM DL SRMYGTSCTFVL G ANDGVL P ARPDENGV L S D DD R EW L KTI --- G VELSSGGR E R L LDE H FLIYM 656
Cdd:TIGR02774 537 TV P ATV D V V T V KSY DL IEPHTAPFVYAI G LTQSNF P KISQNSSL L T D EE R QN L NDA tee G GHFDIASQ E N L KKN H YTMLS 616
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 657 A F S S PSDR L YV S Y P IADA E GKTLLPSMIVKRLEELF P -- HHKERL L TNEP E QVSDEEQ L MYV V --- N KSVAQSF T ASQ L R 731
Cdd:TIGR02774 617 L F N S ATKE L VL S A P QLFN E SEDKESPYLQELIDFGV P lr EKGMNS L GEDK E DIGNYKA L LSR V vay N QQGEMEM T KQD L T 696
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 732 L W TR eydisdvwwstyn VLMSEQDR L QSKK L - FSSLFFRNEV K Q L ERS V SRQ LY -- GERIQG S V S RME TF NACPF S H F AS 808
Cdd:TIGR02774 697 F W SV ------------- LVRYLRKK L DQQG L e IPTITDSLST K T L SKD V LQA LY pa DQPLKL S A S ALT TF YNNQY S Y F LR 763
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 809 HG L H L K E RQFFKLE A PDI G QLF H S ---- SL KL ISDRLRE QKL DWRDLTKE Q CEL F SYDAV E RLAPKLQK EILL S snrhyy 884
Cdd:TIGR02774 764 YV L G L E E EESIHPD A RHH G NYL H R ifer LM KL PGEESFD QKL NQAINETS Q ERE F EALYQ E DAEARYTL EILL D ------ 837
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 885 vkeklqk I VTRVSG IL SEH aka S GFVP I GL E LG FGGK gpl PPLTF Q LK NG CTMELV G R IDR V D KA es S K G LL L RI VDYKS 964
Cdd:TIGR02774 838 ------- I ARSTAP IL RHN --- S AIQV I KE E EN FGGK --- DNFQL Q ID NG RSIFVR G I IDR I D RL -- S D G GS L GV VDYKS 902
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 965 S DKGL D LAEV Y Y GL AL Q ML TYL D - L SITHSAD wlg MRATPA G VL Y F H IHD P MIQSNLPLG LD EIEQ E IF K KF K MK GL LL g 1043
Cdd:TIGR02774 903 S ATQF D IPHF Y N GL SP Q LP TYL A a L KRIAPHE --- GEQPIF G AM Y L H MQE P VQDLMAVKN LD DAVV E AS K AL K YQ GL FS - 978
1050 1060 1070 1080 1090 1100 1110
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 239938591 1044 DQ E VVR L mdttlqegrsniinaglk KD G SLRSDSAAVGEK E FD LL TKHVRRTFQE A G E Q I TD GR VS I E PY KMKNKT 1119
Cdd:TIGR02774 979 EK E KSH L ------------------ AE G YNKNKANLYSDE E LQ LL LDYNKYLYKK A A E T I LS GR FA I N PY TEDGRS 1036
PDDEXK_1
pfam12705 PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
791-1131
2.58e-40
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 149.61
E-value: 2.58e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 791 S V SR M ET FNA CP FSH F ASHG L H L K E R qf FK L E APD I G Q L F H SS L KLIS drlreqkl D W RD L TK E QC E LFSYDAV E R L A P K 870
Cdd:pfam12705 3 S P SR L ET YLT CP LRF F LRYL L G L R E D -- EE L D APD L G T L V H AA L ERFY -------- R W GR L PE E DL E ELLQALL E E L W P E 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 871 -- LQ K EIL lss N R HYYVKEK L QKIVT R VSGI L S E HAK A S - GF V P IGL ELGFGG K gplppltfqlkngc T ME LVGRIDRVD 947
Cdd:pfam12705 73 lg LQ S EIL --- P R LPWLAGR L RRRLE R MLRR L A E WLR A R r GF R P VAV ELGFGG T -------------- T VR LVGRIDRVD 135
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 948 KAESSK gll LRI V DYK SS --- DKGL DL a EV Y Y G la LQ M L T YL DL s ITHSADW LG mra T PAG V LY FHIH DP MI qsnlplgl 1024
Cdd:pfam12705 136 LDGEGY --- LRI I DYK TG sap PQSE DL - DL Y E G -- LQ L L L YL LA - LAAGEKA LG --- G PAG A LY LRLD DP LK -------- 197
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 1025 deieqeifkkfkmkglll G D Q EVV RL M DT T lqegrsniinaglkkdgslrsdsaavg E K EFD L L TKHV R rtfq E AG E Q I T 1104
Cdd:pfam12705 198 ------------------ K D E EVV EP M VL T --------------------------- E D EFD A L LQEL R ---- E LA E E I L 228
330 340
....*....|....*....|....*..
gi 239938591 1105 D G RVSIE P Y K mknkt P C T YC AFK S V C Q 1131
Cdd:pfam12705 229 A G EFPAR P G K ----- K C R YC PYR S I C P 250
Slr0479
COG2887 RecB family exonuclease [Replication, recombination and repair];
791-985
3.63e-15
RecB family exonuclease [Replication, recombination and repair];
Pssm-ID: 442133 [Multi-domain]
Cd Length: 248
Bit Score: 76.61
E-value: 3.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 791 S V SR M ET FNA CP FSHF A SHG L H L KERQFFKLE A P D I G Q L F H SS L KLISDRLRE qkldwr D L TK E Q celfsyd AVER L APK 870
Cdd:COG2887 4 S P SR I ET LLR CP LRYY A RYI L G L RDPLEPPPD A A D R G T L V H AV L ERFYKLPAD ------ E L PA E E ------- LLAL L EEA 70
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 871 LQKEILLSSNRHYYVK E KLQKIVTR vsg I L SEHAKAS G FV P IGL E LG F ggkgplppl TFQ L KN G ct ME L V GRIDR V D KAE 950
Cdd:COG2887 71 WAELGFEDPWAAALWL E RAERLLEA --- F L EWERAPA G LE P VAV E VE F --------- ELE L PG G -- VR L R GRIDR I D RLP 136
170 180 190
....*....|....*....|....*....|....*
gi 239938591 951 SSK gll L RI VDYK SSDKGLDLA E V yy G LAL Q MLT Y 985
Cdd:COG2887 137 DGR --- L VV VDYK TGKAPSTKD E A -- G EDP Q LAL Y 166
RecB
COG1074 3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ...
317-394
1.12e-04
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain]
Cd Length: 866
Bit Score: 46.49
E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 317 AAN R RA E LEGI A RE I HA L VR E -------- KGY R YK D V A I L A R QPEDY k DMVKEVFADYE IP YFIDGKA S MLNH P LIEFIR 388
Cdd:COG1074 415 EDA R ER E ARAV A AR I RR L LA E gttveggg RPV R PG D I A V L V R TRSEA - AAIARALKAAG IP VAASDRL S LFES P EVRDLL 493
....*.
gi 239938591 389 SS L DV L 394
Cdd:COG1074 494 AL L RA L 499
UvrD
COG0210 Superfamily I DNA or RNA helicase [Replication, recombination and repair];
310-438
1.31e-04
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain]
Cd Length: 721
Bit Score: 46.08
E-value: 1.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 310 E ALTVMQ A ANRRA E LEGI A R EI HA L v R E K G YRYK D V A I L A R --- Q PE dykd MVK E VFADYE IPY FID G KASMLNHPL I EF 386
Cdd:COG0210 315 E KVRLYV A PDEEE E ARFV A D EI RE L - H E E G VPLS D I A V L Y R tna Q SR ---- ALE E ALRRAG IPY RVV G GLRFYERAE I KD 389
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 239938591 387 IRSS L DV L KGNWRYE A VF R C vktellfp LN E P KAKVREQ - VDQ L ENYCIAY GI 438
Cdd:COG0210 390 LLAY L RL L ANPDDDV A LL R I -------- LN V P RRGIGAA t LER L REAAREE GI 434
UvrD_C
pfam13361 UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ...
306-669
3.40e-04
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain]
Cd Length: 377
Bit Score: 44.32
E-value: 3.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 306 A E KQ E ALTVMQ A ANRRA E L E G IA R EI HA LV r EKGYR Y K D V A I L A R QPE D y K D MVK E VFADYE IPYF ID G KASMLNHPL I E 385
Cdd:pfam13361 40 V E DG E KIKIIE A ETEEE E A E W IA L EI KK LV - ARDEK Y N D I A V L T R SNS D - A D LIE E ALKKLG IPYF VV G QTKFFRREE I K 117
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 386 F I RSS L DVLKGNWRYEAVF R CVKT ell FPLNEPK A KVRE qvdq LEN Y c IAY G IKGDRWTKG D RFQ Y R - R FV SLDDDFAQT 464
Cdd:pfam13361 118 D I LAY L RLIANKHDSISLK R ILNG --- PKRGIGN A TLER ---- IRE Y - KKR G LRLSDFINP D TLT Y G d P FV IALEQDNIV 189
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 465 DQEI E MEN m L ND T R D W I VP pl FQLQ K RM KK A ktvq EKA E ALY R Y L E e TDV P LKLDQERQRAE D DGRIIEAQQHQQ A WDAV 544
Cdd:pfam13361 190 VFDV E TTG - L DT T E D E I IQ -- IAAI K LN KK G ---- VVI E SFE R F L R - LKK P VGDSLQVHGFS D EFLQENGETPAE A LRDF 261
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239938591 545 IQL LE E ------- FV E MMGDD ----- E IS L DL F QQMIEAGAES L TF S L I ppa LDQVFVGNMDLSRMYGTSCT F VL G AND G 612
Cdd:pfam13361 262 LEK LE N lrelysi LR E YDDIE etpep E DA L RN F LEIATLSNSE L EG S D I --- KERIPIMTIHQAKGLEFDTV F LA G LEE G 338
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 239938591 613 VL P A rpdengvlsdddrewlktigv EL S SGGRER L LD E HF L I Y M A FSSPSD RLY V SY 669
Cdd:pfam13361 339 IF P S --------------------- YR S IKDEGN L EE E RR L F Y V A ITRAKK RLY I SY 374
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
