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Conserved domains on  [gi|586352|sp|P38329|]
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RecName: Full=Vacuolar cation-chloride cotransporter 1; AltName: Full=Vacuolar homolog of CCC family protein 1

Protein Classification

APC family permease( domain architecture ID 1903533)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0055085|GO:0022857
TCDB:  2.A.3

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
AA_permease_2 super family cl45918
Amino acid permease;
45-824 1.41e-133

Amino acid permease;


The actual alignment was detected with superfamily member TIGR00930:

Pssm-ID: 459263 [Multi-domain]  Cd Length: 953  Bit Score: 429.52  E-value: 1.41e-133
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352       45 ECQKVSSKYDPDNPNKDKLGTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGT 124
Cdd:TIGR00930   60 EAEDAEGTKEKPPAGAVKFGWVMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGV 139
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      125 VRGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNLGYSAQGEPPAALGELLprghwhefTYATVIL 204
Cdd:TIGR00930  140 VKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVLDLLRENGSKIMVDPINDIR--------IYGTVTV 211
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      205 FLCFSVAFVGSQTVSRAGNILFLVLAASIFSIPLSALIrSPFTEGGISYTGPSWQTFHDNLLPHLTKGAAGsllkgketF 284
Cdd:TIGR00930  212 VVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTII-PAFDKPAKGFFGLGNEIFSENFIPGIPGPEGG--------F 282
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      285 NDLFGVFFPATAGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPR---RSLYDEV----------- 350
Cdd:TIGR00930  283 FSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRdatGDKNDTLvtnctsaacfs 362
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      351 ---------------QIIQTISSVQWVIFMGEMATSLFSIIVGMLGAAYVLEAIAKDNIIPGLEIFAHS------PLYSL 409
Cdd:TIGR00930  363 ecahntcsyglmnnlQVMSLVSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGygkngePLRAY 442
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      410 IFTWILTQLC-LFSDVNKIATFITMTFLMTFVVMNLACFLLGISSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISA 488
Cdd:TIGR00930  443 LLTAFIAEGFiLIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAA 522
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      489 SVLFLAMILLFLFIHYFSPPKSWGDVSQSLIYHQVRKYLLRLR--QDNIKYWRPQILLFVDNPRTSWNLIRFCNHLKKG- 565
Cdd:TIGR00930  523 LVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEevEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGk 602
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      566 GLYILGHVaVTADFPKQLNELKT---QQKAWMKIRDMaaiKAFVQVGTGPSLIWGIRNVFIGSGLGGMKPNITVVGFfdl 642
Cdd:TIGR00930  603 GLMICGSV-IQGPRLECVKEAQAaeaKIQTWLEKNKV---KAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGY--- 675
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      643 esyrKHIPQSRSQNNLQKQVEI--KATVPRSTCSDVKINVPLPTDECKNETKVNVQQWVQIVEDLSLMQSNIAIAHGfKN 720
Cdd:TIGR00930  676 ----KKDWRQAEPRAWETYIGIihDAFDAHLAVVVVRNSEGLPISVLQVQEELENDCSEDSIELNDGKISTQPDMHL-EA 750
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      721 LEIPNKRdscFPKKTIDLYPIqmcgkveakgdqpaaittnFDTYTLILQLAAILVTVPEWKRThSLRVILfVEQEYHRTN 800
Cdd:TIGR00930  751 STQFQKK---QGKGTIDVWWL-------------------VDDGGLTLLLPYLLTTKKVWKKC-KIRIFV-GAQKDDRSE 806
                          810       820
                   ....*....|....*....|....*
gi 586352      801 ETQR-MKKLLQVLRIDAEVLVVSLD 824
Cdd:TIGR00930  807 QEKKdMATLLYKFRIDAEVIVVLMD 831
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
45-824 1.41e-133

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 429.52  E-value: 1.41e-133
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352       45 ECQKVSSKYDPDNPNKDKLGTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGT 124
Cdd:TIGR00930   60 EAEDAEGTKEKPPAGAVKFGWVMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGV 139
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      125 VRGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNLGYSAQGEPPAALGELLprghwhefTYATVIL 204
Cdd:TIGR00930  140 VKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVLDLLRENGSKIMVDPINDIR--------IYGTVTV 211
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      205 FLCFSVAFVGSQTVSRAGNILFLVLAASIFSIPLSALIrSPFTEGGISYTGPSWQTFHDNLLPHLTKGAAGsllkgketF 284
Cdd:TIGR00930  212 VVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTII-PAFDKPAKGFFGLGNEIFSENFIPGIPGPEGG--------F 282
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      285 NDLFGVFFPATAGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPR---RSLYDEV----------- 350
Cdd:TIGR00930  283 FSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRdatGDKNDTLvtnctsaacfs 362
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      351 ---------------QIIQTISSVQWVIFMGEMATSLFSIIVGMLGAAYVLEAIAKDNIIPGLEIFAHS------PLYSL 409
Cdd:TIGR00930  363 ecahntcsyglmnnlQVMSLVSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGygkngePLRAY 442
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      410 IFTWILTQLC-LFSDVNKIATFITMTFLMTFVVMNLACFLLGISSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISA 488
Cdd:TIGR00930  443 LLTAFIAEGFiLIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAA 522
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      489 SVLFLAMILLFLFIHYFSPPKSWGDVSQSLIYHQVRKYLLRLR--QDNIKYWRPQILLFVDNPRTSWNLIRFCNHLKKG- 565
Cdd:TIGR00930  523 LVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEevEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGk 602
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      566 GLYILGHVaVTADFPKQLNELKT---QQKAWMKIRDMaaiKAFVQVGTGPSLIWGIRNVFIGSGLGGMKPNITVVGFfdl 642
Cdd:TIGR00930  603 GLMICGSV-IQGPRLECVKEAQAaeaKIQTWLEKNKV---KAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGY--- 675
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      643 esyrKHIPQSRSQNNLQKQVEI--KATVPRSTCSDVKINVPLPTDECKNETKVNVQQWVQIVEDLSLMQSNIAIAHGfKN 720
Cdd:TIGR00930  676 ----KKDWRQAEPRAWETYIGIihDAFDAHLAVVVVRNSEGLPISVLQVQEELENDCSEDSIELNDGKISTQPDMHL-EA 750
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      721 LEIPNKRdscFPKKTIDLYPIqmcgkveakgdqpaaittnFDTYTLILQLAAILVTVPEWKRThSLRVILfVEQEYHRTN 800
Cdd:TIGR00930  751 STQFQKK---QGKGTIDVWWL-------------------VDDGGLTLLLPYLLTTKKVWKKC-KIRIFV-GAQKDDRSE 806
                          810       820
                   ....*....|....*....|....*
gi 586352      801 ETQR-MKKLLQVLRIDAEVLVVSLD 824
Cdd:TIGR00930  807 QEKKdMATLLYKFRIDAEVIVVLMD 831
AA_permease pfam00324
Amino acid permease;
68-543 2.08e-43

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 165.19  E-value: 2.08e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352       68 GVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGtVRGGGAYYMISRSLGPEFGGSIG 147
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNG-PVSGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      148 LVFFLGQVFNAgMNAVGIIEPLLYNLGYSaqgeppaalgellpRGHWHEFTYATVILFLCFSVAFVGSQTVSRAGNILFL 227
Cdd:pfam00324   80 WNYWLSWITVL-ALELTAASILIQFWELV--------------PDIPYLWVWGAVFLVLLTIINLVGVKWYGEAEFWFAL 144
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      228 --VLAASIFSIPLSALIRSPFTEGGISYTGPSWQTFHDNLLPHLTKGAAGsllkgketfndLFGVFFPATAGIFAGAGMS 305
Cdd:pfam00324  145 ikIIAIIGFIIVGIILLSGGNPNDGAIFRYLGDNGGKNNFPPGFGKGFIS-----------VFVIAFFAFTGIELVGIAA 213
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      306 SELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRR------------SLYDEVQIIQTISSVQWVIFMGEMATSLF 373
Cdd:pfam00324  214 GEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNdpgllndsasaaSPFVIFFKFLGISGLAPLINAVILTAALS 293
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      374 SIIVGMLGAAYVLEAIAKDNIIPGleIFA-----HSPLYSLIFTWILTQLCLFSdvNKIATFITMTFLMTFVVM-NLACF 447
Cdd:pfam00324  294 AANSSLYSGSRMLYSLARDGLAPK--FLKkvdkrGVPLRAILVSMVISLLALLL--ASLNPAIVFNFLLAISGLsGLIVW 369
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      448 LLGISSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISASVLFLAMILLFLFIHYFSPPKSWGDVSQSLIYHQVRKYL 527
Cdd:pfam00324  370 GLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLFL 449
                          490
                   ....*....|....*...
gi 586352      528 LRL--RQDNIKYWRPQIL 543
Cdd:pfam00324  450 IILigVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
60-506 2.26e-34

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 137.72  E-value: 2.26e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352     60 KDKLGTYDGVFVpTALNVLSILMFLRFGFILGQLGiictiGLLLLSYTIN----LLTTLSISAISTNgTVRGGGAYYMIS 135
Cdd:COG0531   10 KRKLGLFDLVAL-GVGAIIGAGIFVLPGLAAGLAG-----PAAILAWLIAgllaLLVALSYAELASA-FPRAGGAYTYAR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352    136 RSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIepllynlgysaqgeppAALGELLPRGHWheFTYATVILFLCFSVAFVGS 215
Cdd:COG0531   83 RALGPLLGFLAGWALLLSYVLAVAAVAVAFG----------------GYLSSLFPAGGS--VLIALVLILLLTLLNLRGV 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352    216 QTVSRAGNILFLVLAASIFSIPLSALIrspfteggiSYTGPSWQTFhdnlLPHLtkGAAGSLLKGketfndlFGVFFPAT 295
Cdd:COG0531  145 KESAKVNNILTVLKLLVLLLFIVVGLF---------AFDPANFTPF----LPAG--GGLSGVLAA-------LALAFFAF 202
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352    296 AGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRRSLYDE----VQIIQTI--SSVQWVIFMGEMA 369
Cdd:COG0531  203 TGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYDELAASgaplADAAEAVfgPWGAILIALGALL 282
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352    370 TSLFSIIVGMLGAAYVLEAIAKDNIIPglEIFAH------SPLYSLIFTWILTQLCLF---SDVNKIATFITMTFLMTFV 440
Cdd:COG0531  283 SLLGALNASILGASRLLYAMARDGLLP--KVFAKvhprfgTPVNAILLTGVIALLLLLlgaASFTALASLASVGVLLAYL 360
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 586352    441 VMNLACFLLGIsSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISASVLFLAMILLFLFIHYFS 506
Cdd:COG0531  361 LVALAVIVLRR-RRPDLPRPFRVPLPLIPILGILLCLFLLYLLGPGALLIGLVLLAIGLLLYLLYR 425
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
45-824 1.41e-133

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 429.52  E-value: 1.41e-133
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352       45 ECQKVSSKYDPDNPNKDKLGTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGT 124
Cdd:TIGR00930   60 EAEDAEGTKEKPPAGAVKFGWVMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGV 139
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      125 VRGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNLGYSAQGEPPAALGELLprghwhefTYATVIL 204
Cdd:TIGR00930  140 VKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVLDLLRENGSKIMVDPINDIR--------IYGTVTV 211
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      205 FLCFSVAFVGSQTVSRAGNILFLVLAASIFSIPLSALIrSPFTEGGISYTGPSWQTFHDNLLPHLTKGAAGsllkgketF 284
Cdd:TIGR00930  212 VVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTII-PAFDKPAKGFFGLGNEIFSENFIPGIPGPEGG--------F 282
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      285 NDLFGVFFPATAGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPR---RSLYDEV----------- 350
Cdd:TIGR00930  283 FSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRdatGDKNDTLvtnctsaacfs 362
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      351 ---------------QIIQTISSVQWVIFMGEMATSLFSIIVGMLGAAYVLEAIAKDNIIPGLEIFAHS------PLYSL 409
Cdd:TIGR00930  363 ecahntcsyglmnnlQVMSLVSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGygkngePLRAY 442
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      410 IFTWILTQLC-LFSDVNKIATFITMTFLMTFVVMNLACFLLGISSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISA 488
Cdd:TIGR00930  443 LLTAFIAEGFiLIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAA 522
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      489 SVLFLAMILLFLFIHYFSPPKSWGDVSQSLIYHQVRKYLLRLR--QDNIKYWRPQILLFVDNPRTSWNLIRFCNHLKKG- 565
Cdd:TIGR00930  523 LVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEevEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGk 602
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      566 GLYILGHVaVTADFPKQLNELKT---QQKAWMKIRDMaaiKAFVQVGTGPSLIWGIRNVFIGSGLGGMKPNITVVGFfdl 642
Cdd:TIGR00930  603 GLMICGSV-IQGPRLECVKEAQAaeaKIQTWLEKNKV---KAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGY--- 675
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      643 esyrKHIPQSRSQNNLQKQVEI--KATVPRSTCSDVKINVPLPTDECKNETKVNVQQWVQIVEDLSLMQSNIAIAHGfKN 720
Cdd:TIGR00930  676 ----KKDWRQAEPRAWETYIGIihDAFDAHLAVVVVRNSEGLPISVLQVQEELENDCSEDSIELNDGKISTQPDMHL-EA 750
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      721 LEIPNKRdscFPKKTIDLYPIqmcgkveakgdqpaaittnFDTYTLILQLAAILVTVPEWKRThSLRVILfVEQEYHRTN 800
Cdd:TIGR00930  751 STQFQKK---QGKGTIDVWWL-------------------VDDGGLTLLLPYLLTTKKVWKKC-KIRIFV-GAQKDDRSE 806
                          810       820
                   ....*....|....*....|....*
gi 586352      801 ETQR-MKKLLQVLRIDAEVLVVSLD 824
Cdd:TIGR00930  807 QEKKdMATLLYKFRIDAEVIVVLMD 831
AA_permease pfam00324
Amino acid permease;
68-543 2.08e-43

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 165.19  E-value: 2.08e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352       68 GVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGtVRGGGAYYMISRSLGPEFGGSIG 147
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNG-PVSGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      148 LVFFLGQVFNAgMNAVGIIEPLLYNLGYSaqgeppaalgellpRGHWHEFTYATVILFLCFSVAFVGSQTVSRAGNILFL 227
Cdd:pfam00324   80 WNYWLSWITVL-ALELTAASILIQFWELV--------------PDIPYLWVWGAVFLVLLTIINLVGVKWYGEAEFWFAL 144
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      228 --VLAASIFSIPLSALIRSPFTEGGISYTGPSWQTFHDNLLPHLTKGAAGsllkgketfndLFGVFFPATAGIFAGAGMS 305
Cdd:pfam00324  145 ikIIAIIGFIIVGIILLSGGNPNDGAIFRYLGDNGGKNNFPPGFGKGFIS-----------VFVIAFFAFTGIELVGIAA 213
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      306 SELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRR------------SLYDEVQIIQTISSVQWVIFMGEMATSLF 373
Cdd:pfam00324  214 GEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNdpgllndsasaaSPFVIFFKFLGISGLAPLINAVILTAALS 293
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      374 SIIVGMLGAAYVLEAIAKDNIIPGleIFA-----HSPLYSLIFTWILTQLCLFSdvNKIATFITMTFLMTFVVM-NLACF 447
Cdd:pfam00324  294 AANSSLYSGSRMLYSLARDGLAPK--FLKkvdkrGVPLRAILVSMVISLLALLL--ASLNPAIVFNFLLAISGLsGLIVW 369
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      448 LLGISSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISASVLFLAMILLFLFIHYFSPPKSWGDVSQSLIYHQVRKYL 527
Cdd:pfam00324  370 GLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLFL 449
                          490
                   ....*....|....*...
gi 586352      528 LRL--RQDNIKYWRPQIL 543
Cdd:pfam00324  450 IILigVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
60-506 2.26e-34

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 137.72  E-value: 2.26e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352     60 KDKLGTYDGVFVpTALNVLSILMFLRFGFILGQLGiictiGLLLLSYTIN----LLTTLSISAISTNgTVRGGGAYYMIS 135
Cdd:COG0531   10 KRKLGLFDLVAL-GVGAIIGAGIFVLPGLAAGLAG-----PAAILAWLIAgllaLLVALSYAELASA-FPRAGGAYTYAR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352    136 RSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIepllynlgysaqgeppAALGELLPRGHWheFTYATVILFLCFSVAFVGS 215
Cdd:COG0531   83 RALGPLLGFLAGWALLLSYVLAVAAVAVAFG----------------GYLSSLFPAGGS--VLIALVLILLLTLLNLRGV 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352    216 QTVSRAGNILFLVLAASIFSIPLSALIrspfteggiSYTGPSWQTFhdnlLPHLtkGAAGSLLKGketfndlFGVFFPAT 295
Cdd:COG0531  145 KESAKVNNILTVLKLLVLLLFIVVGLF---------AFDPANFTPF----LPAG--GGLSGVLAA-------LALAFFAF 202
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352    296 AGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRRSLYDE----VQIIQTI--SSVQWVIFMGEMA 369
Cdd:COG0531  203 TGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYDELAASgaplADAAEAVfgPWGAILIALGALL 282
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352    370 TSLFSIIVGMLGAAYVLEAIAKDNIIPglEIFAH------SPLYSLIFTWILTQLCLF---SDVNKIATFITMTFLMTFV 440
Cdd:COG0531  283 SLLGALNASILGASRLLYAMARDGLLP--KVFAKvhprfgTPVNAILLTGVIALLLLLlgaASFTALASLASVGVLLAYL 360
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 586352    441 VMNLACFLLGIsSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISASVLFLAMILLFLFIHYFS 506
Cdd:COG0531  361 LVALAVIVLRR-RRPDLPRPFRVPLPLIPILGILLCLFLLYLLGPGALLIGLVLLAIGLLLYLLYR 425
AA_permease_2 pfam13520
Amino acid permease;
126-502 7.29e-18

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 87.37  E-value: 7.29e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      126 RGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYnlgysaqgeppaALGELLPRGHWHEFTYATVILF 205
Cdd:pfam13520   60 RSGGIYVYLENAFGKFVAFLAGWSNWFAYVLGLASSASVAASYLLS------------ALGPDLVPTTWLTYGIAIAILI 127
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      206 LCFSVAFVGSQTVSRAGNILFLVlaasIFSIPLSALIRSPFTEGGISyTGPSWQTFHDNLLPHLTKGaagsllkgkeTFN 285
Cdd:pfam13520  128 IFAIINIRGVRESAKIQNILGIL----KLLLPLILIIILGLVTADGG-GFNLLSGEWHTFFPDGWPG----------VFA 192
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      286 DLFGVFFpATAGIFAGAGMSSELRKpsKSIPKGTLWGLLFTFICYAVVVFSMGCSIPR------RSLYDEVQIIQTISSV 359
Cdd:pfam13520  193 GFLGVLW-SFTGFESAANVSEEVKK--RNVPKAIFIGVIIVGVLYILVNIAFFGVVPDdeialsSGLGQVAALLFQAVGG 269
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      360 QWV--IFMGEMATSLF-SIIVGMLGAAYVLEAIAKDNIIPGLEIFAH-----SPLYSLIFTWILTQLCLF------SDVN 425
Cdd:pfam13520  270 KWGaiIVVILLALSLLgAVNTAIVGASRLLYALARDGVLPFSRFFAKvnkfgSPIRAIILTAILSLILLLlfllspAAYN 349
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      426 KIATFITMTFLMTFVVMNLACFLLGISSaPNFRpsfKYFNRYTTAIGALLSVVAMLIV-----DGISASVLFLAMILLFL 500
Cdd:pfam13520  350 ALLSLSAYGYLLSYLLPIIGLLILRKKR-PDLG---RIPGRWPVAIFGILFSLFLIVAlffppVGPATGSSLNYAIILIV 425

                   ..
gi 586352      501 FI 502
Cdd:pfam13520  426 AF 427
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
199-497 3.43e-07

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 54.44  E-value: 3.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      199 YATVILFLCFSVAFVGSQTVSRAGNIlflvlAASIFSIPLSALIRSPFTEGGISYTGPSWQTFHDNLLPHLTKGAagslL 278
Cdd:TIGR00906  164 FAVCLILLLAVLLSFGVKESAWVNKI-----FTAINILVLLFVIIAGFTKADVANWSITEEKGAGGFMPYGFTGV----L 234
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      279 KGKETfndlfgVFFpATAGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRRSLYDEVQIIQTISS 358
Cdd:TIGR00906  235 SGAAT------CFF-AFIGFDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLLDPDAPFPVAFEY 307
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      359 VQW-----VIFMGEMATSLFSIIVGMLGAAYVLEAIAKDNIIPG----LEIFAHSPL-YSLIFTWILTQLCLFSDVNKIA 428
Cdd:TIGR00906  308 VGWdpakyIVAVGALCGMSTSLLGGMFPLPRVIYAMARDGLLFKwlaqINSKTKTPInATVVSGAIAALMAFLFDLKALV 387
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 586352      429 TFITMTFLMTFVVMNLACFLLgissapNFRPSFKYFN-RYTTAIGALLSVVAMLIV-----DGISASVLFLAMIL 497
Cdd:TIGR00906  388 DLLSIGTLLAYSLVAACVLIL------RYQPGLVYDQaKDTDEKDTLDSWVPFTSKsesqsEGFSLRTLFSGLIL 456
SLC12 pfam03522
Solute carrier family 12;
555-639 1.26e-06

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 52.23  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586352      555 LIRFCNHL-KKGGLYILGHVAVTADFPKQLNELKTQQKAWMKIRDmaaIKAFVQVGTGPSLIWGIRNVFIGSGLGGMKPN 633
Cdd:pfam03522    4 LVDFAHLItKNVSLMICGHVVKGRLSQKLRSELQKKAYRWLRKRK---IKAFYALVDGDNLREGAQALLQASGLGKLKPN 80

                   ....*.
gi 586352      634 ITVVGF 639
Cdd:pfam03522   81 ILLMGY 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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