|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00333 |
PTZ00333 |
triosephosphate isomerase; Provisional |
2-250 |
4.62e-145 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 240365 Cd Length: 255 Bit Score: 405.84 E-value: 4.62e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 2 SAKPQPIAAANWKCNGTTASIEKLVQVFNEHTIS-HDVQCVVAPTFVHIPLVQAKLRNPKYVISAENAI-AKSGAFTGEV 79
Cdd:PTZ00333 1 MMKRKPFVGGNWKCNGTKASIKELIDSFNKLKFDpNNVDVVVAPPSLHIPLVQEKLKNKNFKISSQNVSlTGSGAFTGEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 80 SMPILKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDA 159
Cdd:PTZ00333 81 SAEMLKDLGINWTILGHSERRQYFGETNEIVAQKVKNALENGLKVILCIGETLEEREAGQTSDVLSKQLEAIVKKVSDEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 160 WNQVVLAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASL 239
Cdd:PTZ00333 161 WDNIVIAYEPVWAIGTGKVATPEQAQEVHAFIRKWLAEKVGADVAEATRIIYGGSVNEKNCKELIKQPDIDGFLVGGASL 240
|
250
....*....|.
gi 1351275 240 KPEFRDIIDAT 250
Cdd:PTZ00333 241 KPDFVDIIKSA 251
|
|
| TpiA |
COG0149 |
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase ... |
6-249 |
4.53e-118 |
|
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439919 [Multi-domain] Cd Length: 249 Bit Score: 337.41 E-value: 4.53e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 6 QPIAAANWKCNGTTASIEKLVQVFNEHTISH-DVQCVVAPTFVHIPLVQAKLRNPKYVISAEN-AIAKSGAFTGEVSMPI 83
Cdd:COG0149 3 KPLIAGNWKMNGTLAEAKALLAALAAALADLaDVEVVVCPPFTYLAAVAEALAGSPIALGAQNvHWEDSGAYTGEISAAM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 84 LKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQV 163
Cdd:COG0149 83 LKDLGCRYVIVGHSERRQYFGETDELVNKKVKAALAAGLTPILCVGETLEEREAGKTEEVVARQLKAALAGLSAEQAANV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 164 VLAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE- 242
Cdd:COG0149 163 VIAYEPVWAIGTGKTATPEQAQEVHAFIRALLAELYGAEVAEAVRILYGGSVKPGNAAELFAQPDIDGALVGGASLDAEd 242
|
....*..
gi 1351275 243 FRDIIDA 249
Cdd:COG0149 243 FLAIVRA 249
|
|
| TIM |
cd00311 |
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of ... |
7-248 |
1.01e-115 |
|
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually homodimeric, but in some organisms tetrameric, is ubiqitous and conserved in function across eukaryotes, bacteria and archaea.
Pssm-ID: 238190 Cd Length: 242 Bit Score: 331.04 E-value: 1.01e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 7 PIAAANWKCNGTTASIEKLVQVFNEHTISH-DVQCVVAPTFVHIPLVQAKLRNPKYVISAENA-IAKSGAFTGEVSMPIL 84
Cdd:cd00311 1 PLVAGNWKMNGTLAEALELAKALNAVLKDEsGVEVVVAPPFTYLAAVAEALEGSKIKVGAQNVsPEDSGAFTGEISAEML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 85 KDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLtkDAWNQVV 164
Cdd:cd00311 81 KDAGAKYVIIGHSERRQYFGETDEDVAKKVKAALEAGLTPILCVGETLEEREAGKTEEVVAAQLAAVLAGV--EDLAPVV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 165 LAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGtDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE-F 243
Cdd:cd00311 159 IAYEPVWAIGTGKTASPEQAQEVHAFIRKLLAELYG-EVAEKVRILYGGSVNPENAAELLAQPDIDGVLVGGASLKAEsF 237
|
....*
gi 1351275 244 RDIID 248
Cdd:cd00311 238 LDIIK 242
|
|
| TIM |
pfam00121 |
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic ... |
7-249 |
1.42e-106 |
|
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. TIM plays an important role in several metabolic pathways and is essential for efficient energy production, present in eukaryotes and prokaryotes. TIM is a dimer of identical subunits, each of which is made up of about 250 amino-acid residues. A glutamic acid residue is involved in the catalytic mechanism. The tertiary structure of TIM has eight beta/alpha motifs folded into a barrel structure. The sequence around the active site residue is perfectly conserved in all known TIM's. Deficiencies in TIM are associated with haemolytic anaemia coupled with a progressive, severe neurological disorder.
Pssm-ID: 459680 Cd Length: 244 Bit Score: 307.90 E-value: 1.42e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 7 PIAAANWKCNGTTASIEKLVQVFNEHTISH-DVQCVVAPTFVHIPLVQAKLrNPKYVISAENA-IAKSGAFTGEVSMPIL 84
Cdd:pfam00121 1 PIIAGNWKMNGTLAEAAELLAELAEALADEsGVEVVVAPPFTYLSAVAELL-GSNIKVGAQNVdPEESGAFTGEISAEML 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 85 KDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNqVV 164
Cdd:pfam00121 80 KDLGVSYVIIGHSERRQYFGETDEDVAKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLDAALAGLGAEQKN-LV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 165 LAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGtDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE-F 243
Cdd:pfam00121 159 IAYEPVWAIGTGKTATPEQAQEVHAFIRAVLAELYK-EVAEGVRILYGGSVKPGNAAELAAQPDIDGALVGGASLKAEdF 237
|
....*.
gi 1351275 244 RDIIDA 249
Cdd:pfam00121 238 LDIINA 243
|
|
| tim |
TIGR00419 |
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that ... |
12-242 |
5.28e-49 |
|
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The active site of the enzyme is located between residues 240-258 of the model ([AV]-Y-E-P-[LIVM]-W-[SA]-I-G-T-[GK]) with E being the active site residue. There is a slight deviation from this sequence within the archeal members of this family. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 129513 [Multi-domain] Cd Length: 205 Bit Score: 160.35 E-value: 5.28e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 12 NWK-CNGTTASIEKLVQVFNEHTISHD-VQCVVAPTFVHIPLVQAKLRNPKYvisAENAIA-KSGAFTGEVSMPILKDIG 88
Cdd:TIGR00419 5 NWKtYNESRGMRALEVAKIAEEVASEAgVAVAVAPPFVDLPMIKREVEIPVY---AQHVDAvLSGAHTGEISAEMLKDIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 89 VHWVILGHSERRtyYGETDeiVAQKVSEACKQGFMVIACIgetlqqreanqtaKVVLSQTSAIAakltkdaWNQVVLAYE 168
Cdd:TIGR00419 82 AKGTLINHSERR--MKLAD--IEKKIARLKELGLTSVVCT-------------NNVLTTAAAAA-------LEPDVVAVE 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1351275 169 PVWAIGTGKVATPEQAQEVHLLLRkwVSENIGTDVaaklRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE 242
Cdd:TIGR00419 138 PPELIGTGIPVSPAQPEVVHGSVR--AVKEVNESV----RVLCGAGISTGEDAELAAQLGAEGVLLASGSLKAD 205
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00333 |
PTZ00333 |
triosephosphate isomerase; Provisional |
2-250 |
4.62e-145 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 240365 Cd Length: 255 Bit Score: 405.84 E-value: 4.62e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 2 SAKPQPIAAANWKCNGTTASIEKLVQVFNEHTIS-HDVQCVVAPTFVHIPLVQAKLRNPKYVISAENAI-AKSGAFTGEV 79
Cdd:PTZ00333 1 MMKRKPFVGGNWKCNGTKASIKELIDSFNKLKFDpNNVDVVVAPPSLHIPLVQEKLKNKNFKISSQNVSlTGSGAFTGEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 80 SMPILKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDA 159
Cdd:PTZ00333 81 SAEMLKDLGINWTILGHSERRQYFGETNEIVAQKVKNALENGLKVILCIGETLEEREAGQTSDVLSKQLEAIVKKVSDEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 160 WNQVVLAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASL 239
Cdd:PTZ00333 161 WDNIVIAYEPVWAIGTGKVATPEQAQEVHAFIRKWLAEKVGADVAEATRIIYGGSVNEKNCKELIKQPDIDGFLVGGASL 240
|
250
....*....|.
gi 1351275 240 KPEFRDIIDAT 250
Cdd:PTZ00333 241 KPDFVDIIKSA 251
|
|
| TpiA |
COG0149 |
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase ... |
6-249 |
4.53e-118 |
|
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439919 [Multi-domain] Cd Length: 249 Bit Score: 337.41 E-value: 4.53e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 6 QPIAAANWKCNGTTASIEKLVQVFNEHTISH-DVQCVVAPTFVHIPLVQAKLRNPKYVISAEN-AIAKSGAFTGEVSMPI 83
Cdd:COG0149 3 KPLIAGNWKMNGTLAEAKALLAALAAALADLaDVEVVVCPPFTYLAAVAEALAGSPIALGAQNvHWEDSGAYTGEISAAM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 84 LKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQV 163
Cdd:COG0149 83 LKDLGCRYVIVGHSERRQYFGETDELVNKKVKAALAAGLTPILCVGETLEEREAGKTEEVVARQLKAALAGLSAEQAANV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 164 VLAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE- 242
Cdd:COG0149 163 VIAYEPVWAIGTGKTATPEQAQEVHAFIRALLAELYGAEVAEAVRILYGGSVKPGNAAELFAQPDIDGALVGGASLDAEd 242
|
....*..
gi 1351275 243 FRDIIDA 249
Cdd:COG0149 243 FLAIVRA 249
|
|
| TIM |
cd00311 |
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of ... |
7-248 |
1.01e-115 |
|
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually homodimeric, but in some organisms tetrameric, is ubiqitous and conserved in function across eukaryotes, bacteria and archaea.
Pssm-ID: 238190 Cd Length: 242 Bit Score: 331.04 E-value: 1.01e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 7 PIAAANWKCNGTTASIEKLVQVFNEHTISH-DVQCVVAPTFVHIPLVQAKLRNPKYVISAENA-IAKSGAFTGEVSMPIL 84
Cdd:cd00311 1 PLVAGNWKMNGTLAEALELAKALNAVLKDEsGVEVVVAPPFTYLAAVAEALEGSKIKVGAQNVsPEDSGAFTGEISAEML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 85 KDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLtkDAWNQVV 164
Cdd:cd00311 81 KDAGAKYVIIGHSERRQYFGETDEDVAKKVKAALEAGLTPILCVGETLEEREAGKTEEVVAAQLAAVLAGV--EDLAPVV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 165 LAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGtDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE-F 243
Cdd:cd00311 159 IAYEPVWAIGTGKTASPEQAQEVHAFIRKLLAELYG-EVAEKVRILYGGSVNPENAAELLAQPDIDGVLVGGASLKAEsF 237
|
....*
gi 1351275 244 RDIID 248
Cdd:cd00311 238 LDIIK 242
|
|
| tpiA |
PRK00042 |
triosephosphate isomerase; Provisional |
6-249 |
4.50e-111 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 234589 Cd Length: 250 Bit Score: 319.37 E-value: 4.50e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 6 QPIAAANWKCNGTTASIEKLVQVFNEHTIS-HDVQCVVAPTFVHIPLVQAKLRNPKYVISAENA-IAKSGAFTGEVSMPI 83
Cdd:PRK00042 2 KPIIAGNWKMNKTLAEAKALVEELKAALPDaDGVEVAVAPPFTALASVKEALKGSNIKLGAQNVhPEDSGAFTGEISAEM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 84 LKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQV 163
Cdd:PRK00042 82 LKDLGVKYVIIGHSERRQYFGETDELVNKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLEAALAGLSAEQFANL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 164 VLAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGtDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE- 242
Cdd:PRK00042 162 VIAYEPVWAIGTGKTATPEQAQEVHAFIRAVLAELYG-EVAEKVRILYGGSVKPDNAAELMAQPDIDGALVGGASLKAEd 240
|
....*..
gi 1351275 243 FRDIIDA 249
Cdd:PRK00042 241 FLAIVKA 247
|
|
| PLN02561 |
PLN02561 |
triosephosphate isomerase |
12-251 |
1.02e-108 |
|
triosephosphate isomerase
Pssm-ID: 178175 Cd Length: 253 Bit Score: 313.68 E-value: 1.02e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 12 NWKCNGTTASIEKLVQVFNEHTI--SHDVQCVVAPTFVHIPLVQAKLRnPKYVISAENA-IAKSGAFTGEVSMPILKDIG 88
Cdd:PLN02561 10 NWKCNGTVEEVKKIVTTLNEAEVpsEDVVEVVVSPPFVFLPLVKSLLR-PDFQVAAQNCwVKKGGAFTGEISAEMLVNLG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 89 VHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKdaWNQVVLAYE 168
Cdd:PLN02561 89 IPWVILGHSERRALLGESNEFVGDKVAYALSQGLKVIACVGETLEQRESGSTMDVVAAQTKAIADKVSD--WANVVLAYE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 169 PVWAIGTGKVATPEQAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPEFRDIID 248
Cdd:PLN02561 167 PVWAIGTGKVATPAQAQEVHDELRKWLHKNVSPEVAATTRIIYGGSVTGANCKELAAQPDVDGFLVGGASLKPEFIDIIK 246
|
...
gi 1351275 249 ATR 251
Cdd:PLN02561 247 SAT 249
|
|
| TIM |
pfam00121 |
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic ... |
7-249 |
1.42e-106 |
|
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. TIM plays an important role in several metabolic pathways and is essential for efficient energy production, present in eukaryotes and prokaryotes. TIM is a dimer of identical subunits, each of which is made up of about 250 amino-acid residues. A glutamic acid residue is involved in the catalytic mechanism. The tertiary structure of TIM has eight beta/alpha motifs folded into a barrel structure. The sequence around the active site residue is perfectly conserved in all known TIM's. Deficiencies in TIM are associated with haemolytic anaemia coupled with a progressive, severe neurological disorder.
Pssm-ID: 459680 Cd Length: 244 Bit Score: 307.90 E-value: 1.42e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 7 PIAAANWKCNGTTASIEKLVQVFNEHTISH-DVQCVVAPTFVHIPLVQAKLrNPKYVISAENA-IAKSGAFTGEVSMPIL 84
Cdd:pfam00121 1 PIIAGNWKMNGTLAEAAELLAELAEALADEsGVEVVVAPPFTYLSAVAELL-GSNIKVGAQNVdPEESGAFTGEISAEML 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 85 KDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNqVV 164
Cdd:pfam00121 80 KDLGVSYVIIGHSERRQYFGETDEDVAKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLDAALAGLGAEQKN-LV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 165 LAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGtDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE-F 243
Cdd:pfam00121 159 IAYEPVWAIGTGKTATPEQAQEVHAFIRAVLAELYK-EVAEGVRILYGGSVKPGNAAELAAQPDIDGALVGGASLKAEdF 237
|
....*.
gi 1351275 244 RDIIDA 249
Cdd:pfam00121 238 LDIINA 243
|
|
| PRK13962 |
PRK13962 |
bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional |
7-242 |
2.61e-85 |
|
bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional
Pssm-ID: 237572 [Multi-domain] Cd Length: 645 Bit Score: 266.59 E-value: 2.61e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 7 PIAAANWKCNGTTASIEKLVQVFNEHTISHDVQCVVAPTFVHIPLVQAKLRNPKYVISAENAI-AKSGAFTGEVSMPILK 85
Cdd:PRK13962 399 PIIAGNWKMNKTPAEAKEFVNELKKYVKDAQAEVVVCPPFTALPSVKEAVDGSNIKLGAQNVFyEEKGAYTGEISGPMLA 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 86 DIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQVVL 165
Cdd:PRK13962 479 EIGVEYVIIGHSERRQYFGETDELVNKKVLAALKAGLTPILCVGETLDERESGITFDVVRLQLKAALNGLSAEQVKKVVI 558
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1351275 166 AYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE 242
Cdd:PRK13962 559 AYEPVWAIGTGKVATPEQAQEVHAFIRKLVAELYGEEAARKVRILYGGSVKSENAAGLFNQPDIDGGLVGGASLKAQ 635
|
|
| PLN02429 |
PLN02429 |
triosephosphate isomerase |
1-249 |
2.69e-79 |
|
triosephosphate isomerase
Pssm-ID: 166070 Cd Length: 315 Bit Score: 241.23 E-value: 2.69e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 1 MSAKPQPIAAANWKCNGTTASIEKLVQVFNEHTISHDVQCVVAPTFVHIPLVQAKLRNpKYVISAENA-IAKSGAFTGEV 79
Cdd:PLN02429 60 MAGSGKFFVGGNWKCNGTKDSIAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLTD-RIDISGQNSwVGKGGAFTGEI 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 80 SMPILKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTkdA 159
Cdd:PLN02429 139 SVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGLGVIACIGEKLEEREAGKTFDVCFAQLKAFADAVP--S 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 160 WNQVVLAYEPVWAIGTGKVATPEQAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASL 239
Cdd:PLN02429 217 WDNIVVAYEPVWAIGTGKVASPQQAQEVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASL 296
|
250
....*....|.
gi 1351275 240 K-PEFRDIIDA 249
Cdd:PLN02429 297 KgPEFATIVNS 307
|
|
| PRK14565 |
PRK14565 |
triosephosphate isomerase; Provisional |
11-248 |
1.25e-49 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 237758 Cd Length: 237 Bit Score: 163.01 E-value: 1.25e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 11 ANWKCNGTTASIEKLVQVFNEHTIS--HDVQCVVAPTFVHIPLVQAklRNPKYVISAENAIAK-SGAFTGEVSMPILKDI 87
Cdd:PRK14565 7 ANWKMNGDFSLFSSFLKELSNKLANneITLKLVICPPFTAMSSFVE--CNPNIKLGAQNCFYGsSGGYTGEISAKMLKEC 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 88 GVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKltkdaWNQVVLAY 167
Cdd:PRK14565 85 GCSYVILGHSERRSTFHETDSDIRLKAESAIESGLIPIICVGETLEDRENGMTKDVLLEQCSNCLPK-----HGEFIIAY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 168 EPVWAIGTGKVATPEQAQEVHLLLRKWVSenigtdvaaKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE-FRDI 246
Cdd:PRK14565 160 EPVWAIGGSTIPSNDAIAEAFEIIRSYDS---------KSHIIYGGSVNQENIRDLKSINQLSGVLVGSASLDVDsFCKI 230
|
..
gi 1351275 247 ID 248
Cdd:PRK14565 231 IQ 232
|
|
| tim |
TIGR00419 |
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that ... |
12-242 |
5.28e-49 |
|
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The active site of the enzyme is located between residues 240-258 of the model ([AV]-Y-E-P-[LIVM]-W-[SA]-I-G-T-[GK]) with E being the active site residue. There is a slight deviation from this sequence within the archeal members of this family. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 129513 [Multi-domain] Cd Length: 205 Bit Score: 160.35 E-value: 5.28e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 12 NWK-CNGTTASIEKLVQVFNEHTISHD-VQCVVAPTFVHIPLVQAKLRNPKYvisAENAIA-KSGAFTGEVSMPILKDIG 88
Cdd:TIGR00419 5 NWKtYNESRGMRALEVAKIAEEVASEAgVAVAVAPPFVDLPMIKREVEIPVY---AQHVDAvLSGAHTGEISAEMLKDIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 89 VHWVILGHSERRtyYGETDeiVAQKVSEACKQGFMVIACIgetlqqreanqtaKVVLSQTSAIAakltkdaWNQVVLAYE 168
Cdd:TIGR00419 82 AKGTLINHSERR--MKLAD--IEKKIARLKELGLTSVVCT-------------NNVLTTAAAAA-------LEPDVVAVE 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1351275 169 PVWAIGTGKVATPEQAQEVHLLLRkwVSENIGTDVaaklRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE 242
Cdd:TIGR00419 138 PPELIGTGIPVSPAQPEVVHGSVR--AVKEVNESV----RVLCGAGISTGEDAELAAQLGAEGVLLASGSLKAD 205
|
|
| PRK14905 |
PRK14905 |
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; ... |
36-235 |
2.65e-44 |
|
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; Provisional
Pssm-ID: 184898 [Multi-domain] Cd Length: 355 Bit Score: 152.49 E-value: 2.65e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 36 HDVQCVVAPTFV----HIPLVQAKLRNPKYVISAENAIAK-SGAFTGEVSMPILKDIGVHWVILGHSERRTYYGETDEIV 110
Cdd:PRK14905 38 YDIELFVIPSYIalkdAVEAAASETGHPKIKIGAQNMNAKdKGQFTGEISPLMLKELGIELVMIGHSERRHVLKETDQEE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 111 AQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQVVLAYEPVWAIGTGKV-ATPEQAQEVHL 189
Cdd:PRK14905 118 NEKVLAALKHGFITLLCIGETLEQKNYNISDEVLRTQLKIGLHGVSAEQLPHLFIAYEPVWAIGEGGIpASAEYADEKHA 197
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1351275 190 LLRKWVSENIGTDvAAKLRILYGGSVNAANAATLYAKPDINGFLVG 235
Cdd:PRK14905 198 IIKQCLFELFAEE-SKKIPVLYGGSVNLENANELIMKPHIDGLFIG 242
|
|
| PRK15492 |
PRK15492 |
triosephosphate isomerase; Provisional |
18-235 |
5.75e-40 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 185389 Cd Length: 260 Bit Score: 138.59 E-value: 5.75e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 18 TTASIEKLVQVFNEHTISHDVQCVVAPTFVHIP-LVQAKLRNPK---YVISAENAIAK-SGAFTGEVSMPILKDIGVHWV 92
Cdd:PRK15492 19 ATDFLAKLSELADDIPADKDIELFVIPSFTAIQdAIAATLAIPHdhpIIIGAQNMNPNdNGQFTGDISPLMLKEIGTQLV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 93 ILGHSERRTYYGETDEIVAQKVSEACKQGFMVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQVVLAYEPVWA 172
Cdd:PRK15492 99 MIGHSERRHKFGETDQEENAKVLAALKHDFTTLLCVGETLEQKNYGISDEILRTQLKIGLHGINPDQLAKLRIAYEPVWA 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1351275 173 IGTGKV-ATPEQAQEVHLLLRKWVSENIGtDVAAKLRILYGGSVNAANAATLYAKPDINGFLVG 235
Cdd:PRK15492 179 IGEAGIpASADYADEKHAVIKQCLIELFG-DAGDDIPVFYGGSVNAENANELFGQPHIDGLFIG 241
|
|
| PRK04302 |
PRK04302 |
triosephosphate isomerase; Provisional |
37-176 |
2.46e-06 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 235274 Cd Length: 223 Bit Score: 47.17 E-value: 2.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1351275 37 DVQCVVAPTFVHIPLVQAKLRNPKYV--ISAENAiaksGAFTGEVSMPILKDIGVHWVILGHSERRTYYGETDEIVaqkv 114
Cdd:PRK04302 36 GVRIAVAPQALDIRRVAEEVDIPVYAqhVDPVEP----GSHTGHILPEAVKDAGAVGTLINHSERRLTLADIEAVV---- 107
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1351275 115 sEACKQ-GFMVIACigetlqqreANQTAkvvlsqTSAIAAKLTKDAwnqvvLAYEPVWAIGTG 176
Cdd:PRK04302 108 -ERAKKlGLESVVC---------VNNPE------TSAAAAALGPDY-----VAVEPPELIGTG 149
|
|
| |
