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Conserved domains on  [gi|3915712|sp|P53363|]
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RecName: Full=Ribosomal RNA small subunit methyltransferase G; AltName: Full=16S rRNA 7-methylguanosine methyltransferase; Short=16S rRNA m7G methyltransferase; AltName: Full=Glucose-inhibited division protein B

Protein Classification

16S rRNA (guanine(527)-N(7))-methyltransferase RsmG( domain architecture ID 10495022)

16S rRNA (guanine(527)-N(7))-methyltransferase RsmG specifically methylates the N7 position of guanine in position 527 of 16S rRNA; requires the intact 30S subunit for methylation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GidB pfam02527
rRNA small subunit methyltransferase G; This is a family of bacterial glucose inhibited ...
 20-204 2.08e-47

rRNA small subunit methyltransferase G; This is a family of bacterial glucose inhibited division proteins these are probably involved in the regulation of cell devision. GidB has been shown to be a methyltransferase G specific to the rRNA small subunit. Previously identified as a glucose-inhibited division protein B that appears to be present and in a single copy in all complete eubacterial genomes so far sequenced. GidB specifically methylates the N7 position of a guanosine in 16S rRNA.


:

Pssm-ID: 396880  Cd Length: 184  Bit Score: 153.98  E-value: 2.08e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712     20 DLQKINLYIKRILLLNTRFNLISNSNSNFNSIlnLHVIDSLLGLSTVKEINPsEVLDVGSGAGFPGIILAIFDSSRKYYL 99
Cdd:pfam02527   1 QIEKLKRYLQLLLKWNKRYNLTSITEPNELLE--RHLLDSLVVLEYLDNDRD-HVLDVGSGAGFPGIPLAIARPDKKVTL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712    100 LERSKKKSTFLKMIKLELDLENVKILEYEIEKEKKKYEF--ITIRAFRNMNEYALILKNLLKGGGLIMAYKGKFDRINLE 177
Cdd:pfam02527  78 LESLLKKINFLEEVKSELGLDNVTIVHARAEEYQPEEQYdvITSRAVASLNELTEWTLPLLKPGGYFLAYKGKQAEDELE 157

                         170       180
                  ....*....|....*....|....*..
gi 3915712    178 VNQIKNLFSKIEVKSLNSKLRVDRNLV 204
Cdd:pfam02527 158 ELDKACQVLGVEVLSVPSLGAGDRHLV 184
 
Name Accession Description Interval E-value
GidB pfam02527
rRNA small subunit methyltransferase G; This is a family of bacterial glucose inhibited ...
 20-204 2.08e-47

rRNA small subunit methyltransferase G; This is a family of bacterial glucose inhibited division proteins these are probably involved in the regulation of cell devision. GidB has been shown to be a methyltransferase G specific to the rRNA small subunit. Previously identified as a glucose-inhibited division protein B that appears to be present and in a single copy in all complete eubacterial genomes so far sequenced. GidB specifically methylates the N7 position of a guanosine in 16S rRNA.


Pssm-ID: 396880  Cd Length: 184  Bit Score: 153.98  E-value: 2.08e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712     20 DLQKINLYIKRILLLNTRFNLISNSNSNFNSIlnLHVIDSLLGLSTVKEINPsEVLDVGSGAGFPGIILAIFDSSRKYYL 99
Cdd:pfam02527   1 QIEKLKRYLQLLLKWNKRYNLTSITEPNELLE--RHLLDSLVVLEYLDNDRD-HVLDVGSGAGFPGIPLAIARPDKKVTL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712    100 LERSKKKSTFLKMIKLELDLENVKILEYEIEKEKKKYEF--ITIRAFRNMNEYALILKNLLKGGGLIMAYKGKFDRINLE 177
Cdd:pfam02527  78 LESLLKKINFLEEVKSELGLDNVTIVHARAEEYQPEEQYdvITSRAVASLNELTEWTLPLLKPGGYFLAYKGKQAEDELE 157

                         170       180
                  ....*....|....*....|....*..
gi 3915712    178 VNQIKNLFSKIEVKSLNSKLRVDRNLV 204
Cdd:pfam02527 158 ELDKACQVLGVEVLSVPSLGAGDRHLV 184
rsmG_gidB TIGR00138
16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; RsmG was previously called GidB ...
 55-207 2.81e-37

16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; RsmG was previously called GidB (glucose-inhibited division protein B). It is present and a single copy in nearly all complete eubacterial genomes. It is missing only from some obligate intracellular species of various lineages (Chlamydiae, Ehrlichia, Wolbachia, Anaplasma, Buchnera, etc.). RsmG shows a methytransferase fold in its the crystal structure, and acts as a 7-methylguanosine (m(7)G) methyltransferase, apparently specific to 16S rRNA. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272928  Cd Length: 181  Bit Score: 127.76  E-value: 2.81e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712     55 HVIDSLLGLSTVKEINpseVLDVGSGAGFPGIILAIFDSSRKYYLLERSKKKSTFLKMIKLELDLENVKILEYEIEKEKK 134
Cdd:TIGR00138  30 HILDSLALLPYLDGKR---VIDIGSGAGFPGIPLAIARPELKLTLLESNHKKVAFLREVKAELGLNNVEIVNGRAEDYQH 106

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 3915712    135 KYEF--ITIRAFRNMNEYALILKNLLKGGGLIMAYKGKFDRINLEVNQIKNLFSKIEVKSLNSKLRVDRNLVLLY 207
Cdd:TIGR00138 107 EEQFdiITSRALASLNVLLELTLNLLKVGGYFLAYKGKKYLDEIEEAKEKIQVLGVEPLEVPPLTGPDRHLVVLK 181
RsmG COG0357
16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B) [Translation, ...
 55-208 3.32e-28

16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B) [Translation, ribosomal structure and biogenesis]; 16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B) is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440126  Cd Length: 211  Bit Score: 105.23  E-value: 3.32e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712   55 HVIDSLLGLSTVKEiNPSEVLDVGSGAGFPGIILAIFDSSRKYYLLERSKKKSTFLKMIKLELDLENVKILEYEIEKEKK 134
Cdd:COG0357  53 HILDSLALLPLLPK-EGARVLDVGSGAGFPGIPLAIARPDLQVTLVDSLGKKIAFLREVVRELGLKNVTVVHGRAEELAP 131

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 3915712  135 KYEF--ITIRAFRNMNEYALILKNLLKGGGLIMAYKGKfdRINLEVNQIKNLFSK-IEVKSLN-SKLRVDRNLVLLYR 208
Cdd:COG0357 132 REKFdvVTARAVAPLPDLLELALPLLKPGGRLLALKGP--DAEEELAEAPKALKVlEEVEELTlPGLDAERHLVVIKK 207
 
Name Accession Description Interval E-value
GidB pfam02527
rRNA small subunit methyltransferase G; This is a family of bacterial glucose inhibited ...
 20-204 2.08e-47

rRNA small subunit methyltransferase G; This is a family of bacterial glucose inhibited division proteins these are probably involved in the regulation of cell devision. GidB has been shown to be a methyltransferase G specific to the rRNA small subunit. Previously identified as a glucose-inhibited division protein B that appears to be present and in a single copy in all complete eubacterial genomes so far sequenced. GidB specifically methylates the N7 position of a guanosine in 16S rRNA.


Pssm-ID: 396880  Cd Length: 184  Bit Score: 153.98  E-value: 2.08e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712     20 DLQKINLYIKRILLLNTRFNLISNSNSNFNSIlnLHVIDSLLGLSTVKEINPsEVLDVGSGAGFPGIILAIFDSSRKYYL 99
Cdd:pfam02527   1 QIEKLKRYLQLLLKWNKRYNLTSITEPNELLE--RHLLDSLVVLEYLDNDRD-HVLDVGSGAGFPGIPLAIARPDKKVTL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712    100 LERSKKKSTFLKMIKLELDLENVKILEYEIEKEKKKYEF--ITIRAFRNMNEYALILKNLLKGGGLIMAYKGKFDRINLE 177
Cdd:pfam02527  78 LESLLKKINFLEEVKSELGLDNVTIVHARAEEYQPEEQYdvITSRAVASLNELTEWTLPLLKPGGYFLAYKGKQAEDELE 157

                         170       180
                  ....*....|....*....|....*..
gi 3915712    178 VNQIKNLFSKIEVKSLNSKLRVDRNLV 204
Cdd:pfam02527 158 ELDKACQVLGVEVLSVPSLGAGDRHLV 184
rsmG_gidB TIGR00138
16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; RsmG was previously called GidB ...
 55-207 2.81e-37

16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; RsmG was previously called GidB (glucose-inhibited division protein B). It is present and a single copy in nearly all complete eubacterial genomes. It is missing only from some obligate intracellular species of various lineages (Chlamydiae, Ehrlichia, Wolbachia, Anaplasma, Buchnera, etc.). RsmG shows a methytransferase fold in its the crystal structure, and acts as a 7-methylguanosine (m(7)G) methyltransferase, apparently specific to 16S rRNA. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272928  Cd Length: 181  Bit Score: 127.76  E-value: 2.81e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712     55 HVIDSLLGLSTVKEINpseVLDVGSGAGFPGIILAIFDSSRKYYLLERSKKKSTFLKMIKLELDLENVKILEYEIEKEKK 134
Cdd:TIGR00138  30 HILDSLALLPYLDGKR---VIDIGSGAGFPGIPLAIARPELKLTLLESNHKKVAFLREVKAELGLNNVEIVNGRAEDYQH 106

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 3915712    135 KYEF--ITIRAFRNMNEYALILKNLLKGGGLIMAYKGKFDRINLEVNQIKNLFSKIEVKSLNSKLRVDRNLVLLY 207
Cdd:TIGR00138 107 EEQFdiITSRALASLNVLLELTLNLLKVGGYFLAYKGKKYLDEIEEAKEKIQVLGVEPLEVPPLTGPDRHLVVLK 181
RsmG COG0357
16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B) [Translation, ...
 55-208 3.32e-28

16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B) [Translation, ribosomal structure and biogenesis]; 16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B) is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440126  Cd Length: 211  Bit Score: 105.23  E-value: 3.32e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3915712   55 HVIDSLLGLSTVKEiNPSEVLDVGSGAGFPGIILAIFDSSRKYYLLERSKKKSTFLKMIKLELDLENVKILEYEIEKEKK 134
Cdd:COG0357  53 HILDSLALLPLLPK-EGARVLDVGSGAGFPGIPLAIARPDLQVTLVDSLGKKIAFLREVVRELGLKNVTVVHGRAEELAP 131

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 3915712  135 KYEF--ITIRAFRNMNEYALILKNLLKGGGLIMAYKGKfdRINLEVNQIKNLFSK-IEVKSLN-SKLRVDRNLVLLYR 208
Cdd:COG0357 132 REKFdvVTARAVAPLPDLLELALPLLKPGGRLLALKGP--DAEEELAEAPKALKVlEEVEELTlPGLDAERHLVVIKK 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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