|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-429 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 771.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 1 MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EELEMFKTDNIST-ENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIK 159
Cdd:PRK01117 81 KEIDELEARGVDVrERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 160 LKAQIDAKNEIVKNIYGKEELfDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVT 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAV-DFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 240 SSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAA 319
Cdd:PRK01117 240 SSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 320 RVNGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVA 399
Cdd:PRK01117 320 RVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|
gi 1242338120 400 KIEELVGVSVDMVSVGPNRAQTIIRRNIFA 429
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFA 429
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-425 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 754.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 3 TVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 83 LEMFKTDNIST-ENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKLK 161
Cdd:COG0104 81 IDGLEARGVDVrSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 162 AQIDAKNEIVKNIYGKEElFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTSS 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEP-LDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 242 HPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARV 321
Cdd:COG0104 240 NTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 322 NGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVAKI 401
Cdd:COG0104 320 NGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 1242338120 402 EELVGVSVDMVSVGPNRAQTIIRR 425
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-422 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 741.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 5 AIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELE 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 85 MFKTDNIS-TENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKLKAQ 163
Cdd:pfam00709 81 ELEERGIDvPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 164 IDAKNEIVKNIYGkeELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTSSHP 243
Cdd:pfam00709 161 LELKNKLLEKLYG--EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 244 TSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNG 323
Cdd:pfam00709 239 TAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRING 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 324 LTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVAKIEE 403
Cdd:pfam00709 319 VTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 1242338120 404 LVGVSVDMVSVGPNRAQTI 422
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 679.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 3 TVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 83 LEMFKTDNI-STENIKISDRAHVIFPYHKELDALSEEARgdlkIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKLK 161
Cdd:smart00788 81 IEELEAKGVdVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 162 AQIDAKNEIVKNIYGKEElFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTSS 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEP-VDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 242 HPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARV 321
Cdd:smart00788 236 NTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 322 NGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVAKI 401
Cdd:smart00788 316 NGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 1242338120 402 EELVGVSVDMVSVGPNRAQTII 423
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
6-429 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 561.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 6 IVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEM 85
Cdd:TIGR00184 2 VVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEMEY 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 86 FKTDNIST-ENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKLKAQI 164
Cdd:TIGR00184 82 LEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNIL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 165 DAKNEIVKNIYGKEElFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTSSHPT 244
Cdd:TIGR00184 162 EYLNEQLVKYYKDEG-VDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 245 SGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGL 324
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 325 TSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVAKIEEL 404
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|....*
gi 1242338120 405 VGVSVDMVSVGPNRAQTIIRRNIFA 429
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRKELL 425
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-423 |
7.65e-175 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 491.24 E-value: 7.65e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 2 KTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLE 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 82 ELEMFKTDNI-STENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDlmdkdkfaikl 160
Cdd:cd03108 81 EIEELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 161 kaqidakneivkniygkeelfdfetiyneylgyaeqirKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTS 240
Cdd:cd03108 150 --------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTS 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 241 SHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAAR 320
Cdd:cd03108 192 SNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVR 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 321 VNGLTSISFMLLDVltgfdkikvctsykmgdkiitdfpaslddlakcepvyeeldgwneditqidnfddlpeNAKKYVAK 400
Cdd:cd03108 272 INGLTELALTKLDV----------------------------------------------------------NAQKYIER 293
|
410 420
....*....|....*....|...
gi 1242338120 401 IEELVGVSVDMVSVGPNRAQTII 423
Cdd:cd03108 294 IEELLGVPITYISVGPDREQTII 316
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-323 |
4.50e-31 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 120.55 E-value: 4.50e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 5 AIVGSQWGDEGKGKVIDYLATQA--DVVVRGqGGNNAGHTLV-VEGKKYALHLIPSGVLNPN-TVNIIGNGIVFDPKGFL 80
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAapDVVVRA-AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPlKQVLIGPGSEIDLEVLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EELEMFKtDN--ISTENIKISDRAHVIFPY-HKEldalsEEARGDLKIGTTKKGIGPCYMDKTERSGiricDLMDKDKFA 157
Cdd:NF038379 82 EEIEELE-DAghDVGKRLLIHEQATVIELHkHVE-----EEAGPMTKIGSTKKGIGAARAAKIRRNP----STLGDAEGD 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 158 IKLKAQIDAKNEIVkniygkeelfdfetiyneylgyAEQIRKYVADTsvIVYDAVRagkkVLFEGAQGTLLDLDLGTYPF 237
Cdd:NF038379 152 FGEGAVRDQPWEIA----------------------ERVVDNALYDF--ALQAAER----IQIEGTQGYSLGLHAGFYPY 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 238 VTSSHPTSGGFAIGAGIGPNMIKD--VVGIVKAYTTRVGE--GPFVTEQINETGDKIReQGHEFGVTTGRPRRCGWFDAV 313
Cdd:NF038379 204 CTSRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVAGwsGNSYPDQGETTWEELG-LPEELTTVTKKVRRVGTFSAE 282
|
330
....*....|
gi 1242338120 314 IVKYAARVNG 323
Cdd:NF038379 283 QVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-429 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 771.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 1 MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EELEMFKTDNIST-ENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIK 159
Cdd:PRK01117 81 KEIDELEARGVDVrERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 160 LKAQIDAKNEIVKNIYGKEELfDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVT 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAV-DFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 240 SSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAA 319
Cdd:PRK01117 240 SSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 320 RVNGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVA 399
Cdd:PRK01117 320 RVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|
gi 1242338120 400 KIEELVGVSVDMVSVGPNRAQTIIRRNIFA 429
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFA 429
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-425 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 754.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 3 TVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 83 LEMFKTDNIST-ENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKLK 161
Cdd:COG0104 81 IDGLEARGVDVrSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 162 AQIDAKNEIVKNIYGKEElFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTSS 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEP-LDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 242 HPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARV 321
Cdd:COG0104 240 NTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 322 NGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVAKI 401
Cdd:COG0104 320 NGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 1242338120 402 EELVGVSVDMVSVGPNRAQTIIRR 425
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-422 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 741.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 5 AIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELE 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 85 MFKTDNIS-TENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKLKAQ 163
Cdd:pfam00709 81 ELEERGIDvPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 164 IDAKNEIVKNIYGkeELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTSSHP 243
Cdd:pfam00709 161 LELKNKLLEKLYG--EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 244 TSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNG 323
Cdd:pfam00709 239 TAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRING 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 324 LTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVAKIEE 403
Cdd:pfam00709 319 VTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 1242338120 404 LVGVSVDMVSVGPNRAQTI 422
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 679.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 3 TVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 83 LEMFKTDNI-STENIKISDRAHVIFPYHKELDALSEEARgdlkIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKLK 161
Cdd:smart00788 81 IEELEAKGVdVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 162 AQIDAKNEIVKNIYGKEElFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTSS 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEP-VDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 242 HPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARV 321
Cdd:smart00788 236 NTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 322 NGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVAKI 401
Cdd:smart00788 316 NGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 1242338120 402 EELVGVSVDMVSVGPNRAQTII 423
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
6-429 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 561.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 6 IVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEM 85
Cdd:TIGR00184 2 VVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEMEY 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 86 FKTDNIST-ENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKLKAQI 164
Cdd:TIGR00184 82 LEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNIL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 165 DAKNEIVKNIYGKEElFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTSSHPT 244
Cdd:TIGR00184 162 EYLNEQLVKYYKDEG-VDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 245 SGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGL 324
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 325 TSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYVAKIEEL 404
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|....*
gi 1242338120 405 VGVSVDMVSVGPNRAQTIIRRNIFA 429
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRKELL 425
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
1-425 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 536.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 1 MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV-VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGF 79
Cdd:PLN02513 2 SQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 80 LEELEMFKTDNISTEN-IKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAI 158
Cdd:PLN02513 82 FEEIDGLESNGVSCEGrLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 159 KLKAQIDAKNEIVKNIYGKEELFDFETIYneYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFV 238
Cdd:PLN02513 162 KLRELLADAAARFEGFEYDASMVEEEVEA--YKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 239 TSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYA 318
Cdd:PLN02513 240 TSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 319 ARVNGLTSISFMLLDVLTGFDKIKVCTSYKMGD-KIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKY 397
Cdd:PLN02513 320 CQINGFTSLNLTKLDVLSGLPEIKIGVAYKTPDgKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAY 399
|
410 420
....*....|....*....|....*...
gi 1242338120 398 VAKIEELVGVSVDMVSVGPNRAQTIIRR 425
Cdd:PLN02513 400 VERIEELVGVPVHYIGVGPGRDALIVKP 427
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
2-424 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 517.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 2 KTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLE 81
Cdd:PTZ00350 13 KVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLLE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 82 ELEMFKTDNIS-TENIKISDRAHVIFPYHKELDALSEEARGDL--KIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAI 158
Cdd:PTZ00350 93 EIEQLTKKGINlLGRLYISDRAHLVFDLHQAIDGIQESEKGKGgtQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFEK 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 159 KLKAQIDAKNEIVKNiygkeELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFV 238
Cdd:PTZ00350 173 KYRKLVEKLQEQYNI-----EEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 239 TSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYA 318
Cdd:PTZ00350 248 TSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 319 ARVNGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITD--FPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKK 396
Cdd:PTZ00350 328 QMINGFDSINLTKLDVLSGLKEIKICVNYKNKGTGLEIgrYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQK 407
|
410 420
....*....|....*....|....*...
gi 1242338120 397 YVAKIEELVGVSVDMVSVGPNRAQTIIR 424
Cdd:PTZ00350 408 YVLFIEELLGVPIVWIGVGPNRENMIVK 435
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-423 |
7.65e-175 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 491.24 E-value: 7.65e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 2 KTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLE 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 82 ELEMFKTDNI-STENIKISDRAHVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDlmdkdkfaikl 160
Cdd:cd03108 81 EIEELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 161 kaqidakneivkniygkeelfdfetiyneylgyaeqirKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVTS 240
Cdd:cd03108 150 --------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTS 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 241 SHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAAR 320
Cdd:cd03108 192 SNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVR 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 321 VNGLTSISFMLLDVltgfdkikvctsykmgdkiitdfpaslddlakcepvyeeldgwneditqidnfddlpeNAKKYVAK 400
Cdd:cd03108 272 INGLTELALTKLDV----------------------------------------------------------NAQKYIER 293
|
410 420
....*....|....*....|...
gi 1242338120 401 IEELVGVSVDMVSVGPNRAQTII 423
Cdd:cd03108 294 IEELLGVPITYISVGPDREQTII 316
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
1-423 |
9.31e-149 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 429.37 E-value: 9.31e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 1 MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFL 80
Cdd:PRK13787 1 MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EELEMFKTDNIST-ENIKISDRAHVIFPYHKELDALSEEARG-DLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDkFAI 158
Cdd:PRK13787 81 EECDRLQKEGFPVkDKLLLSDACHLLFPYHSQIDSARETTSSqEHKIGTTKKGIGICYADKMMRTGLRVGDLLDKS-YKR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 159 KLKAQIDAKNEIVKNIYGKEELfDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFV 238
Cdd:PRK13787 160 RLKHLVDEKNRELDKLYGMPPV-SYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 239 TSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYA 318
Cdd:PRK13787 239 TSSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 319 ARVNGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASldDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYV 398
Cdd:PRK13787 319 VRINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPSQ--GLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYI 396
|
410 420
....*....|....*....|....*
gi 1242338120 399 AKIEELVGVSVDMVSVGPNRAQTII 423
Cdd:PRK13787 397 SALEKWIGVKINLVSTGPDRKDTII 421
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
1-422 |
9.03e-147 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 424.21 E-value: 9.03e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 1 MKTVaIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVnIIGNGIVFDPKGFL 80
Cdd:PRK13786 1 MFTI-ITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARV-LIGPGVVLNPEVLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EELEMFKTD--NISTENIKISDRAHVIFPYHKELDALSEEARGDlKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAI 158
Cdd:PRK13786 79 EEIDMLEKHgvKVDAEKLGIDAKTSIIMPYHIELDGLRESARTE-KIGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 159 KLKAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFV 238
Cdd:PRK13786 158 RLEELAPQKEKEIKELGGDPSIVRDEALIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 239 TSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYA 318
Cdd:PRK13786 238 TSSSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 319 ARVNGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPENAKKYV 398
Cdd:PRK13786 318 IYLNGYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYV 397
|
410 420
....*....|....*....|....
gi 1242338120 399 AKIEELVGVSVDMVSVGPNRAQTI 422
Cdd:PRK13786 398 ERLEELMGVPIKYISVGPGREQTF 421
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
1-421 |
7.60e-140 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 405.73 E-value: 7.60e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 1 MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFL 80
Cdd:PRK13788 1 MPGIAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EELEMFKTDNISTEnIKISDRAHVIFPYHKELDAlseeaRGDLkIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL 160
Cdd:PRK13788 81 EERENLRAGGLNPK-LLISERAHLVLPHHKYVDG-----RKNF-VGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRERV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 161 KAQIDAKNEIVKniygkEELFDFETIYNEYLG-YAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFVT 239
Cdd:PRK13788 154 ERLLEAKPNSTR-----EAGWDTVEKALADLApMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 240 SSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQG----HEFGVTTGRPRRCGWFDAVIV 315
Cdd:PRK13788 229 SSHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 316 KYAARVNGLTSISFMLLDVLTGFDKIKVCTSYKMGDKiitdfpaslddlakcePVYEELDGWNeDITQIDNFDDLPENAK 395
Cdd:PRK13788 309 KYACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDGQ----------------PVYKELPGWG-DLDGVKSREALPKEAQ 371
|
410 420
....*....|....*....|....*.
gi 1242338120 396 KYVAKIEELVGVSVDMVSVGPNRAQT 421
Cdd:PRK13788 372 AYLELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
1-416 |
5.81e-137 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 398.32 E-value: 5.81e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 1 MKTVaIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFL 80
Cdd:PRK13783 1 MKRV-IVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EELEMFKTDNI-STENIKISDRAHVIFPYHKELDALSEEARGDlKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIK 159
Cdd:PRK13783 80 EELEELKEKFPdYSGRIFISELAHVVLPVHKELDEIIESVRKN-AIGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 160 LkaqidakNEIV---KNIYGKEelFDFETIYNEYLGYAEQIRKYVADTSVIVydAVRAGKKVLFEGAQGTLLDLDLGTYP 236
Cdd:PRK13783 159 L-------EKILslyKKLYGIE--FDVEKMMEDLLTFYEKIKDLVVSPVEIK--RILEEKSVLFEGTQGVLLDLDVGTYP 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 237 FVTSSHpTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVK 316
Cdd:PRK13783 228 YVTSSN-CSTTGVSAGMGFPVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLR 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 317 YAARVNGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDfPASLDDLAKCEPVYEELDGWNEdiTQIDNFDdlpenakK 396
Cdd:PRK13783 307 YAIEVSGVDSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGWKS--LEDKNFL-------K 376
|
410 420
....*....|....*....|
gi 1242338120 397 YVAKIEELVGVSVDMVSVGP 416
Cdd:PRK13783 377 FVDFIERETGRKIAYISTGP 396
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
3-428 |
5.20e-134 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 392.58 E-value: 5.20e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 3 TVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNpNTVNIIGNGIVFDPKGFLEE 82
Cdd:PRK13785 2 TVTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVR-GKIGVLGNGCVVNPETLFDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 83 LEMFKTDNIsTENIKISDRAHVIFPYHKELDALSEEARG--DLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL 160
Cdd:PRK13785 81 IDALRERGL-DPDVRVAERAHVILPYHRVLDGIEEEAKSdsDLEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 161 KAQIDAKNEIVKNIYGKE-----ELFDFETIYNEYLGYAEQIRK--YVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLG 233
Cdd:PRK13785 160 EYVVPQKRALAEDVYGLDasetpEAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDGDNVMLEGAQGTSIDIDHG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 234 TYPFVTSSHPTSGGFAIGAGIGPNMIKD--VVGIVKAYTTRVGEGPFVTE---------------QINETGDKIREQGHE 296
Cdd:PRK13785 240 NYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTElggvegdtpdeggrpDEEELATYIREEGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 297 FGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDVLTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDG 376
Cdd:PRK13785 320 YGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNFRSFDG 399
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1242338120 377 WNE---DITQIDNFDDLPENAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIF 428
Cdd:PRK13785 400 WPEvdwAAVAEEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVLENPF 454
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
1-428 |
1.73e-113 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 339.30 E-value: 1.73e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 1 MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFL 80
Cdd:PRK13784 1 MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EELEMFKTDNI--STENIKISDRAHVIFPYHKELDALSEEARGDlKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAI 158
Cdd:PRK13784 81 EEITRLQAKGIaiSAENLFVSESCTIITSYHKLLDAVRESNTSE-KIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 159 KLKAQIDAKNEIVKNIYgKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFV 238
Cdd:PRK13784 160 RLAISLAEKETLFRDLY-KVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 239 TSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYA 318
Cdd:PRK13784 239 TSSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 319 ARVNGLTSISFMLLDVLTGFDKIKVCTSYKM-GDKIITDFPASldDLAKCEPVYEELDGWNEDitQIDNFDDLPENAKKY 397
Cdd:PRK13784 319 AKCSNLTSIALTKVDVLSDMDTLKVCIGYKYeGKEIYCAYPGI--DLYKVEPILVEMEPFSID--ETVTKDNMPAALKTY 394
|
410 420 430
....*....|....*....|....*....|.
gi 1242338120 398 VAKIEELVGVSVDMVSVGPNRAQTIIRRNIF 428
Cdd:PRK13784 395 LKTIENHVGIPISSLAYGPSREQILFFEDYF 425
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
1-425 |
1.26e-77 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 244.02 E-value: 1.26e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 1 MKTVAIVGSQWGDEGKGKVIDYLATQ--ADVVVRGQGGNNAGHTLVVEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKG 78
Cdd:PRK04293 1 MTCTIVVGGFFGDEGKGKIIAYLALKdkPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 79 FLEELEMFKtdniSTENIKISDRAHVIFPYHKELDALSEEARGdlKIGTTKKGIGPCYMDKTERSGiricdlmdkdkfai 158
Cdd:PRK04293 81 LLKEVEELN----VGGRVFVDYRCGIIEEKHVEEDRSDEHLSK--KIGSTGTGCGPANADRVLRRL-------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 159 KLkaqidAKneivkniygkeelfDFEtiyneylgyaeQIRKYVADTSVIVYDAVRAGKKVLFEGAQGTLLDLDLGTYPFV 238
Cdd:PRK04293 141 KL-----AK--------------DVE-----------ELEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYV 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 239 TSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEGPFVTEQINETGDKIREQghEFGVTTGRPRRCGWFDAVIVKYA 318
Cdd:PRK04293 191 TSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELARRA 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 319 ARVNGLTSISfmlldvLTGFDKIkvctsykmgdkiitdFPAslddlakCEPVYEeldgwneditqidnFDDLPENAKKYV 398
Cdd:PRK04293 269 ARINGATQIA------ITKLDKL---------------DKE-------AYGVTE--------------YDKLPPEAKKFI 306
|
410 420
....*....|....*....|....*..
gi 1242338120 399 AKIEELVGVSVDMVSVGPNRAQTIIRR 425
Cdd:PRK04293 307 EEIEEELGVPVTLISTGPELEDTIDLR 333
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-323 |
4.50e-31 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 120.55 E-value: 4.50e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 5 AIVGSQWGDEGKGKVIDYLATQA--DVVVRGqGGNNAGHTLV-VEGKKYALHLIPSGVLNPN-TVNIIGNGIVFDPKGFL 80
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAapDVVVRA-AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPlKQVLIGPGSEIDLEVLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EELEMFKtDN--ISTENIKISDRAHVIFPY-HKEldalsEEARGDLKIGTTKKGIGPCYMDKTERSGiricDLMDKDKFA 157
Cdd:NF038379 82 EEIEELE-DAghDVGKRLLIHEQATVIELHkHVE-----EEAGPMTKIGSTKKGIGAARAAKIRRNP----STLGDAEGD 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 158 IKLKAQIDAKNEIVkniygkeelfdfetiyneylgyAEQIRKYVADTsvIVYDAVRagkkVLFEGAQGTLLDLDLGTYPF 237
Cdd:NF038379 152 FGEGAVRDQPWEIA----------------------ERVVDNALYDF--ALQAAER----IQIEGTQGYSLGLHAGFYPY 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 238 VTSSHPTSGGFAIGAGIGPNMIKD--VVGIVKAYTTRVGE--GPFVTEQINETGDKIReQGHEFGVTTGRPRRCGWFDAV 313
Cdd:NF038379 204 CTSRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVAGwsGNSYPDQGETTWEELG-LPEELTTVTKKVRRVGTFSAE 282
|
330
....*....|
gi 1242338120 314 IVKYAARVNG 323
Cdd:NF038379 283 QVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
4-425 |
1.19e-19 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 91.65 E-value: 1.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 4 VAIVGSQWGDEGKGKVIDYLATQ--ADVVVRGQGGNNAGHTLVVE-GKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFL 80
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 81 EElEMFKtdnISTENIKISDRAH-----VIFPYHKELDALSEEARgdlkiGTTKKGIGPCYMDKTERSGIRICDLMDKDK 155
Cdd:PTZ00351 252 EK-EIIQ---LIDAGIDYRDRLFignvcIVTPYHKLLDLLGSAAN-----SSTLKGMAPVHGSKVMKRGIRLDHIFNDDE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 156 fAIKLKAQIDAKNEI----VKNIYG-------KEELFDFETIYNEYLGYAEQIRKYV--------------------ADT 204
Cdd:PTZ00351 323 -TLRKRLEKDMDTYLgllkVKNLSDadvvrlcREENSDGVVRVPDYVIAFAQAKDKVeflvklyrdrvrhnpdfparCDV 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 205 SVIVYDAVRAGKKVLFEGAQGTLL-DLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVV-GIVKAY-TTRVGEG----P 277
Cdd:PTZ00351 402 TYELHAAVLRGEKVLLEGPQSYWLsNARTKFWESTTSADTTAAGLLAASQLNFQKFKSVVlNVHKAPgSSRVGIGacpsS 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 278 FV---------------------------------------------------TEQINETGD-------KIREQGH--EF 297
Cdd:PTZ00351 482 FVpqdyfsaqniktlrdlpsatcanfeavqrtlfrdgfphsndkarhngimapVEYSDETGDynigvamAIASAQHhgEC 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1242338120 298 GVTTGRPRRCGWFDAVIVKYAARVNGlTSISFMLLDVLTGFDKIKVCTS-----------------YKMGDKIITDFPA- 359
Cdd:PTZ00351 562 GAVTKKPRVCGFFDCVLQHEVNSIQG-PYLTISALDRGDEYDKVGVTIAyvyynpegkqvdvnghvYKNGDIIRAGDPVp 640
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1242338120 360 SLDDLAKCEPVYEELDGWNED---ITQIDNFDDLPENAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRR 425
Cdd:PTZ00351 641 SEPALYHCHPIVKLIDGWRDNpiaAAKRRRNAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDIIYLR 709
|
|
| |
