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penicillin-binding protein [Bacillus toyonensis]
Protein Classification
peptidoglycan D,D-transpeptidase FtsI family protein ( domain architecture ID 11433609 )
peptidoglycan D,D-transpeptidase FtsI (penicillin-binding protein (PBP) 2) family protein is a membrane-associated enzyme that is most likely involved in the synthesis of cross-linked peptidoglycan
List of domain hits
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
17-701
1.35e-137
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 416.15
E-value: 1.35e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 17 HIPF RL NV LF FI V F LLF SAIIIQ L GKV Q IID G ET Y RNEVNKKEDV TV ST P V PRG KMF DR E G K V IVN N K P LRTVTYTKMKG 96
Cdd:COG0768 9 LFRR RL LL LF LL V L LLF LLLVGR L FYL Q VVE G DE Y AELAEENRIR TV PI P A PRG LIY DR N G N V LAT N V P VYSLYADPEEV 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 97 V D SK E V lkv A RE LA G L IEMSQ E DMD K ltetdkkdfwm Q L NE K RA aekvtkadeskfrkqeiegkeldkkveelrreritq 176
Cdd:COG0768 89 K D PE E T --- A EK LA K L LGLDP E ELR K ----------- K L KK K SR ------------------------------------ 118
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 177 eelkelskddlevlaikskmntgykm T P QIV K KDV S QN E Y A IV se R LAS LPGV DTTVDWE R E YP NDKILRSI LG S V SNE N 256
Cdd:COG0768 119 -------------------------- F P VYL K RNL S PE E A A RI -- R ALK LPGV YVEAEYK R Y YP YGELAAHV LG Y V GEI N 170
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 257 eglpreqleyylvrdyn RN D R IGKS YI EK Q YED A L H G MKEQS R NIT D KA G NI IR T - EKVTEGKS G NN L M LT V D M DLQK KV 335
Cdd:COG0768 171 ----------------- GG D G IGKS GL EK A YED L L R G TPGKR R VEV D AR G RV IR D l GEEKPPVP G KD L V LT I D S DLQK IA 233
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 336 EE S L E K NLRAFHS sepmm DRAF VV M M N PK N G Q IL S MA GK ------ KI V NKDG vmqi E DYALGTMTSS YE L GST V K GA T LL 409
Cdd:COG0768 234 EE A L K K AVEEYKA ----- KSGA VV V M D PK T G E IL A MA SY psfdpn LF V GGPD ---- E PLRNRAVQGT YE P GST F K PF T AA 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 410 SGYQAEA I K P F T H F FD a P M Y FKGSTKPKKS W KD -- F G DIDDLR AL QV SSNV YMFNTV L KM a GI N yvpnnpldikqetfn K 487
Cdd:COG0768 305 AALEEGV I T P D T T F DC - P G Y YRVGGRTIRD W DR gg H G TLTLTE AL AK SSNV GFYKLA L RL - GI D --------------- K 367
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 488 MRY Y FRQ FGLG VS TGIDLP N E SI G QMGRTDNI - PG FLLDYA IGQ YDTY TPLQLAQ YIST IANGG YRM KP QI V Q EI REQP n 566
Cdd:COG0768 368 LYD Y LKK FGLG QK TGIDLP G E AS G LLPSPKRW y PG ETATMS IGQ GLSV TPLQLAQ AYAA IANGG VLV KP HL V K EI VDPD - 446
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 567 rpedv G K V IRS i E SV VL N RV d MDTSYINH V K EG FRR V FQ E AD GT GTG t FKGLP Y KP AGKTGTA ET V ygges DIG RDEN Y N 646
Cdd:COG0768 447 ----- G E V VKE - E PE VL R RV - ISPETAET V R EG MEG V VN E PG GT ARR - AAIPG Y RV AGKTGTA QV V ----- DIG NGGY Y K 513
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1258586900 647 RK kc YNLTLA G Y AP Y D a D P EV A FS VVV PWVNNDKS G VNS A -- IGK EI LD AY FD L KAK 701
Cdd:COG0768 514 GR -- HIASFV G F AP A D - N P RY A VA VVV ENPGGGAY G GTV A ap VFR EI ME AY LR L LGP 567
V_ATP_synt_G super family
cl46932 vacuolar ATP synthase, subunit G; This model describes the vacuolar ATP synthase G subunit in ...
137-224
3.09e-03
vacuolar ATP synthase, subunit G; This model describes the vacuolar ATP synthase G subunit in eukaryotes and includes members from diverse groups e.g., fungi, plants, parasites etc. V-ATPases are multi-subunit enzymes composed of two functional domains: A transmembrane Vo domain and a peripheral catalytic domain V1. The G subunit is one of the subunits of the catalytic domain. V-ATPases are responsible for the acidification of endosomes and lysosomes, which are part of the central vacuolar system. [Energy metabolism, ATP-proton motive force interconversion]
TIGR01147 :Pssm-ID: 130217 [Multi-domain]
Cd Length: 113
Bit Score: 37.89
E-value: 3.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 137 EKRAAEKV TK A DES K FRKQEIEGK E LD K K VE ELRRE R it QE E L KE LSKDD L E - VL A IKS K MNTGYKMTPQIV KK D V SQ N E 215
Cdd:TIGR01147 15 EKRAAEKV SE A RKR K TKRLKQAKE E AQ K E VE KYKQQ R -- EK E F KE FEAKH L G g NG A AEE K AEAETQAKIREI KK A V QK N K 92
....*....
gi 1258586900 216 Y A IVSER L A 224
Cdd:TIGR01147 93 D A VIKDL L H 101
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
17-701
1.35e-137
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 416.15
E-value: 1.35e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 17 HIPF RL NV LF FI V F LLF SAIIIQ L GKV Q IID G ET Y RNEVNKKEDV TV ST P V PRG KMF DR E G K V IVN N K P LRTVTYTKMKG 96
Cdd:COG0768 9 LFRR RL LL LF LL V L LLF LLLVGR L FYL Q VVE G DE Y AELAEENRIR TV PI P A PRG LIY DR N G N V LAT N V P VYSLYADPEEV 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 97 V D SK E V lkv A RE LA G L IEMSQ E DMD K ltetdkkdfwm Q L NE K RA aekvtkadeskfrkqeiegkeldkkveelrreritq 176
Cdd:COG0768 89 K D PE E T --- A EK LA K L LGLDP E ELR K ----------- K L KK K SR ------------------------------------ 118
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 177 eelkelskddlevlaikskmntgykm T P QIV K KDV S QN E Y A IV se R LAS LPGV DTTVDWE R E YP NDKILRSI LG S V SNE N 256
Cdd:COG0768 119 -------------------------- F P VYL K RNL S PE E A A RI -- R ALK LPGV YVEAEYK R Y YP YGELAAHV LG Y V GEI N 170
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 257 eglpreqleyylvrdyn RN D R IGKS YI EK Q YED A L H G MKEQS R NIT D KA G NI IR T - EKVTEGKS G NN L M LT V D M DLQK KV 335
Cdd:COG0768 171 ----------------- GG D G IGKS GL EK A YED L L R G TPGKR R VEV D AR G RV IR D l GEEKPPVP G KD L V LT I D S DLQK IA 233
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 336 EE S L E K NLRAFHS sepmm DRAF VV M M N PK N G Q IL S MA GK ------ KI V NKDG vmqi E DYALGTMTSS YE L GST V K GA T LL 409
Cdd:COG0768 234 EE A L K K AVEEYKA ----- KSGA VV V M D PK T G E IL A MA SY psfdpn LF V GGPD ---- E PLRNRAVQGT YE P GST F K PF T AA 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 410 SGYQAEA I K P F T H F FD a P M Y FKGSTKPKKS W KD -- F G DIDDLR AL QV SSNV YMFNTV L KM a GI N yvpnnpldikqetfn K 487
Cdd:COG0768 305 AALEEGV I T P D T T F DC - P G Y YRVGGRTIRD W DR gg H G TLTLTE AL AK SSNV GFYKLA L RL - GI D --------------- K 367
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 488 MRY Y FRQ FGLG VS TGIDLP N E SI G QMGRTDNI - PG FLLDYA IGQ YDTY TPLQLAQ YIST IANGG YRM KP QI V Q EI REQP n 566
Cdd:COG0768 368 LYD Y LKK FGLG QK TGIDLP G E AS G LLPSPKRW y PG ETATMS IGQ GLSV TPLQLAQ AYAA IANGG VLV KP HL V K EI VDPD - 446
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 567 rpedv G K V IRS i E SV VL N RV d MDTSYINH V K EG FRR V FQ E AD GT GTG t FKGLP Y KP AGKTGTA ET V ygges DIG RDEN Y N 646
Cdd:COG0768 447 ----- G E V VKE - E PE VL R RV - ISPETAET V R EG MEG V VN E PG GT ARR - AAIPG Y RV AGKTGTA QV V ----- DIG NGGY Y K 513
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1258586900 647 RK kc YNLTLA G Y AP Y D a D P EV A FS VVV PWVNNDKS G VNS A -- IGK EI LD AY FD L KAK 701
Cdd:COG0768 514 GR -- HIASFV G F AP A D - N P RY A VA VVV ENPGGGAY G GTV A ap VFR EI ME AY LR L LGP 567
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
20-697
6.11e-103
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 327.17
E-value: 6.11e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 20 F R LN VL FFI V FL LF SAIIIQ L GKV Q I I D GE T Y RNEVNKKEDVT V ST P V PRG KMF DR E G KVIVN N K P LRTVTYTKM K GV D S 99
Cdd:TIGR03423 1 R R AL VL GGL V LA LF GVLAAR L FYL Q V I R GE E Y ATLSEDNRIRL V PI P P PRG LIL DR N G VLLAD N R P SFSLEIVPE K VD D L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 100 KEV L kva RE LA G L IEMSQ ED mdkltetdkkdfwmqlnekraaekvtkadeskfrkqeiegke LDKKVE EL R R E R itqeel 179
Cdd:TIGR03423 81 DAT L --- DR LA K L LDLDP ED ------------------------------------------ IARFLK EL K R S R ------ 109
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 180 kelskddlevlaikskmnt GYK mt P QIV K K D VSQN E Y A IVSERLAS LPGV DTTVDWE R E YP NDKILRSI LG S V S -- NE NE 257
Cdd:TIGR03423 110 ------------------- RFE -- P IPL K S D LTEE E V A RFAVNQYR LPGV EIEARLK R Y YP YGELAAHV LG Y V G ei NE ED 168
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 258 glp R E Q LE Y ylv RD Y NRN D R IGKS Y IEK Q YED A L H G MKEQSRNITDKA G NI IRT EKVTEGKS G NN L M LT V D MD LQ KKV E E 337
Cdd:TIGR03423 169 --- L E R LE P --- AN Y AGG D Y IGKS G IEK Y YED E L R G KPGYREVEVNAR G RV IRT LSRVPPVP G KD L V LT I D AR LQ QAA E K 242
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 338 S L EKN lrafhssepmmd R AF VV M M N P KN G Q IL S M agkki V NK --------- DG VMQ i E DY AL ----------- GTMTSS Y 397
Cdd:TIGR03423 243 A L GGR ------------ R GA VV V M D P RT G E IL A M ----- V ST psfdpnlfv DG ISS - K DY KA llndpdrplln RAIQGV Y 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 398 EL GST V K GATL L SGYQAEA I K P F T HFFD a P M YF KGSTKPKKS WK D -- F G DI D DLR A LQV S SN VY MFNTV L KM a GI N yvpn 475
Cdd:TIGR03423 305 PP GST F K PVVA L AALEEGV I T P E T RIYC - P G YF QLGGRRFRC WK R gg H G RV D LRK A IEE S CD VY FYQLA L RL - GI D ---- 378
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 476 npldikqetfn K MRY Y FRQ FG L G VS TGIDLP N E SI G QMG --------- RTDNI PG FL L DYA IGQ - Y DTY TPLQLA QYIST 545
Cdd:TIGR03423 379 ----------- K IAE Y AKR FG F G QK TGIDLP G E KS G LVP srewkrkrf GQPWY PG DT L NVS IGQ g Y VLV TPLQLA VATAA 447
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 546 I ANGG YRM KP QI V QE I REQ pnrped V G K V I R SI E SV VL NRVDMDTSYINH V K EG F R R V FQEAD GT GTGTFK GLPYK P AGK 625
Cdd:TIGR03423 448 L ANGG KLY KP HL V KS I EDP ------ D G G V V R RT E PE VL RPLPISPENLDV V R EG M R D V VNGPG GT ARRARL GLPYK M AGK 521
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1258586900 626 TGTA ET V ygges DIGRD E N Y NRKKC - YN L T ---- LAGY APYD a D P EV A FS V V vpw V NNDKS G VNS A -- I GKE I L DAY FD 697
Cdd:TIGR03423 522 TGTA QV V ----- SLKQG E K Y DAEQI p ER L R dhal FVAF APYD - N P KI A VA V I --- V EHGGG G SSA A ap I ARK I M DAY LL 591
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
356-693
3.19e-67
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 223.45
E-value: 3.19e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 356 AFV V MMN PK N G QI L S M A GK KIVNKD G vm Q I EDYALGTM TS S YE L GST V K GA T L L SGYQAEAI KP FTHF FD A P MYFK G S t K 435
Cdd:pfam00905 1 GSA V VLD PK T G EV L A M V GK PSYDPN G -- F I GPLRNRAV TS R YE P GST F K PF T A L AALDNGVL KP DETI FD W P GKQQ G G - K 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 436 PKKS W K - D FGD I DD LR - AL QV SSN V YM FNTVL K M aginyvpnn PL D ikqetfn K M R Y Y FRQ FG L G VS TGI D LP N E SI G QM 513
Cdd:pfam00905 78 SIGD W N q D QVG I GT LR q AL EY SSN W YM QKLAQ K L --------- GA D ------- K L R S Y LKK FG Y G NK TGI G LP G E NA G YL 141
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 514 GRTD n IP G FLLDYA IG qy D T Y TPLQ L AQ YIST IANGG YRMK P QI V QE I REQPNRPEDVGKV I RS iesvvlnrvdmdt S YI 593
Cdd:pfam00905 142 TPYW - LE G ATASFG IG -- L T I TPLQ Q AQ AYAA IANGG KLVP P HL V KS I EDKVDPKVLNKLP I SK ------------- S TA 205
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 594 NH VK EGF R R V fq EA DGTGTGT FKGLP YK P AGKTGTA ETV yggesdi G RDENYNRKKCYNLTLA GYAP Y D a D P EV AF S V VV 673
Cdd:pfam00905 206 EK VK DML R L V -- VN DGTGTGT AAVPG YK V AGKTGTA QVA ------- G PKGGGYYDGAQIGWFV GYAP A D - N P KY AF A V LI 275
330 340
....*....|....*....|.
gi 1258586900 674 PWVNNDKS G VNS A - I G K E IL D 693
Cdd:pfam00905 276 DDPKRYYG G KVA A p I F K D IL E 296
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
21-713
5.30e-42
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 162.25
E-value: 5.30e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 21 R LN V L F FIVF LL FSAI I IQ L GKV QI IDGET Y RNEV N KKEDVT V STPVP RG KMF DR E G KVIVN N kpl RT V t Y T kmkgvdsk 100
Cdd:PRK10795 21 R AL V A F LGIL LL TGVL I AN L YNL QI VRFTD Y QTRS N ENRIKL V PIAPS RG IIY DR N G TPLAL N --- RT I - Y Q -------- 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 101 evlkvarelagl I EM SQ E DM D K L TE T dkkdfwmq L NEK R AAEKV T KA D ESK FRK qeiegkeldkkv E EL R RE R I T Q eelk 180
Cdd:PRK10795 89 ------------ L EM MP E KV D N L QQ T -------- L DAL R SVVDL T DD D IAA FRK ------------ E RA R SR R F T S ---- 132
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 181 elskddlev LAI K SKMN tgykmtpqivkk D V SQNEY A IVSE R L asl PGV DTTVDWE R E YP NDKI L RSIL G S VS NE N ---- 256
Cdd:PRK10795 133 --------- IPV K TNLT ------------ E V QVARF A VNQY R F --- PGV EVKGYQR R Y YP YGSA L THVI G Y VS KI N dkdv 188
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 257 E G L PR E QL eyyl VRD Y NRNDR IGK SY IE KQ YED A LHG MKEQSRNITDKA G NI IR TEKVTEGKS G NNLM LT V D MD LQ KKV E 336
Cdd:PRK10795 189 E R L DK E GK ---- LAN Y AATHD IGK LG IE RY YED V LHG KTGYEEVEVNNR G RV IR QLHEQPPQA G HDIY LT L D LK LQ QYI E 264
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 337 ES L EKN lrafhssepmmd RA F VV MMN P KN G Q IL SMAGKK ---------- I VN KD -- G VMQIEDYA L GTMTSS -- Y ELG ST 402
Cdd:PRK10795 265 TL L AGS ------------ RA A VV VTD P RT G G IL ALVSTP sydpnlfvdg I SS KD ys G LLNDPNRP L INRATQ gv Y PPA ST 332
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 403 VK GATLL S GYQ A EA I KPF T HF FD a P MYFK -- GS T K PKKS WK DF G D -- IDDLRA L QV S SNVYMFNTVLK M a GI N yvpnnpl 478
Cdd:PRK10795 333 VK PYVAV S ALS A GV I TRN T SL FD - P GWWQ lp GS E K RYRD WK KW G H gr LNVTKS L EE S ADTFFYQVAYD M - GI D ------- 403
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 479 dikqetfn KMRYYFRQ FG L G VS TGIDL PN E SI G Q M G -------------- RT D N IP gflld YA IGQ - Y D T Y TP L Q LAQYI 543
Cdd:PRK10795 404 -------- RLSEWMGK FG Y G HY TGIDL AE E RS G N M P trewkqkrfkkpwy QG D T IP ----- VG IGQ g Y W T A TP I Q MSKAL 470
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 544 S T IA N G G YRMK P QIVQEIR E Q pnrpedv GK VIRSIESVVLNRV D MDTS Y INHV K E G FRR V FQEAD GT GTGT F KGL PYK P A 623
Cdd:PRK10795 471 M T LI N D G IVKV P HLLMSTA E D ------- GK QVPWVQPHEPPVG D IHSG Y WEIA K D G MYG V ANRPN GT AHKY F ASA PYK I A 543
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 624 G K T GTA E t V Y G gesd IGRD E N YN RK K C ------ YN L TL A g Y APY D a D P E VA FSVVV pwvnn DKS G VNS A I G --- KE ILD a 694
Cdd:PRK10795 544 A K S GTA Q - V F G ---- LKAN E T YN AH K I aerlrd HK L MT A - F APY N - N P Q VA VAIIL ----- ENG G AGP A V G tim RQ ILD - 610
730
....*....|....*....
gi 1258586900 695 YFD L kak RS N ANSV P V E Q P 713
Cdd:PRK10795 611 HIM L --- GD N NTDL P A E N P 626
V_ATP_synt_G
TIGR01147 vacuolar ATP synthase, subunit G; This model describes the vacuolar ATP synthase G subunit in ...
137-224
3.09e-03
vacuolar ATP synthase, subunit G; This model describes the vacuolar ATP synthase G subunit in eukaryotes and includes members from diverse groups e.g., fungi, plants, parasites etc. V-ATPases are multi-subunit enzymes composed of two functional domains: A transmembrane Vo domain and a peripheral catalytic domain V1. The G subunit is one of the subunits of the catalytic domain. V-ATPases are responsible for the acidification of endosomes and lysosomes, which are part of the central vacuolar system. [Energy metabolism, ATP-proton motive force interconversion]
Pssm-ID: 130217 [Multi-domain]
Cd Length: 113
Bit Score: 37.89
E-value: 3.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 137 EKRAAEKV TK A DES K FRKQEIEGK E LD K K VE ELRRE R it QE E L KE LSKDD L E - VL A IKS K MNTGYKMTPQIV KK D V SQ N E 215
Cdd:TIGR01147 15 EKRAAEKV SE A RKR K TKRLKQAKE E AQ K E VE KYKQQ R -- EK E F KE FEAKH L G g NG A AEE K AEAETQAKIREI KK A V QK N K 92
....*....
gi 1258586900 216 Y A IVSER L A 224
Cdd:TIGR01147 93 D A VIKDL L H 101
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
17-701
1.35e-137
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 416.15
E-value: 1.35e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 17 HIPF RL NV LF FI V F LLF SAIIIQ L GKV Q IID G ET Y RNEVNKKEDV TV ST P V PRG KMF DR E G K V IVN N K P LRTVTYTKMKG 96
Cdd:COG0768 9 LFRR RL LL LF LL V L LLF LLLVGR L FYL Q VVE G DE Y AELAEENRIR TV PI P A PRG LIY DR N G N V LAT N V P VYSLYADPEEV 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 97 V D SK E V lkv A RE LA G L IEMSQ E DMD K ltetdkkdfwm Q L NE K RA aekvtkadeskfrkqeiegkeldkkveelrreritq 176
Cdd:COG0768 89 K D PE E T --- A EK LA K L LGLDP E ELR K ----------- K L KK K SR ------------------------------------ 118
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 177 eelkelskddlevlaikskmntgykm T P QIV K KDV S QN E Y A IV se R LAS LPGV DTTVDWE R E YP NDKILRSI LG S V SNE N 256
Cdd:COG0768 119 -------------------------- F P VYL K RNL S PE E A A RI -- R ALK LPGV YVEAEYK R Y YP YGELAAHV LG Y V GEI N 170
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 257 eglpreqleyylvrdyn RN D R IGKS YI EK Q YED A L H G MKEQS R NIT D KA G NI IR T - EKVTEGKS G NN L M LT V D M DLQK KV 335
Cdd:COG0768 171 ----------------- GG D G IGKS GL EK A YED L L R G TPGKR R VEV D AR G RV IR D l GEEKPPVP G KD L V LT I D S DLQK IA 233
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 336 EE S L E K NLRAFHS sepmm DRAF VV M M N PK N G Q IL S MA GK ------ KI V NKDG vmqi E DYALGTMTSS YE L GST V K GA T LL 409
Cdd:COG0768 234 EE A L K K AVEEYKA ----- KSGA VV V M D PK T G E IL A MA SY psfdpn LF V GGPD ---- E PLRNRAVQGT YE P GST F K PF T AA 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 410 SGYQAEA I K P F T H F FD a P M Y FKGSTKPKKS W KD -- F G DIDDLR AL QV SSNV YMFNTV L KM a GI N yvpnnpldikqetfn K 487
Cdd:COG0768 305 AALEEGV I T P D T T F DC - P G Y YRVGGRTIRD W DR gg H G TLTLTE AL AK SSNV GFYKLA L RL - GI D --------------- K 367
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 488 MRY Y FRQ FGLG VS TGIDLP N E SI G QMGRTDNI - PG FLLDYA IGQ YDTY TPLQLAQ YIST IANGG YRM KP QI V Q EI REQP n 566
Cdd:COG0768 368 LYD Y LKK FGLG QK TGIDLP G E AS G LLPSPKRW y PG ETATMS IGQ GLSV TPLQLAQ AYAA IANGG VLV KP HL V K EI VDPD - 446
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 567 rpedv G K V IRS i E SV VL N RV d MDTSYINH V K EG FRR V FQ E AD GT GTG t FKGLP Y KP AGKTGTA ET V ygges DIG RDEN Y N 646
Cdd:COG0768 447 ----- G E V VKE - E PE VL R RV - ISPETAET V R EG MEG V VN E PG GT ARR - AAIPG Y RV AGKTGTA QV V ----- DIG NGGY Y K 513
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1258586900 647 RK kc YNLTLA G Y AP Y D a D P EV A FS VVV PWVNNDKS G VNS A -- IGK EI LD AY FD L KAK 701
Cdd:COG0768 514 GR -- HIASFV G F AP A D - N P RY A VA VVV ENPGGGAY G GTV A ap VFR EI ME AY LR L LGP 567
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
20-697
6.11e-103
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 327.17
E-value: 6.11e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 20 F R LN VL FFI V FL LF SAIIIQ L GKV Q I I D GE T Y RNEVNKKEDVT V ST P V PRG KMF DR E G KVIVN N K P LRTVTYTKM K GV D S 99
Cdd:TIGR03423 1 R R AL VL GGL V LA LF GVLAAR L FYL Q V I R GE E Y ATLSEDNRIRL V PI P P PRG LIL DR N G VLLAD N R P SFSLEIVPE K VD D L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 100 KEV L kva RE LA G L IEMSQ ED mdkltetdkkdfwmqlnekraaekvtkadeskfrkqeiegke LDKKVE EL R R E R itqeel 179
Cdd:TIGR03423 81 DAT L --- DR LA K L LDLDP ED ------------------------------------------ IARFLK EL K R S R ------ 109
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 180 kelskddlevlaikskmnt GYK mt P QIV K K D VSQN E Y A IVSERLAS LPGV DTTVDWE R E YP NDKILRSI LG S V S -- NE NE 257
Cdd:TIGR03423 110 ------------------- RFE -- P IPL K S D LTEE E V A RFAVNQYR LPGV EIEARLK R Y YP YGELAAHV LG Y V G ei NE ED 168
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 258 glp R E Q LE Y ylv RD Y NRN D R IGKS Y IEK Q YED A L H G MKEQSRNITDKA G NI IRT EKVTEGKS G NN L M LT V D MD LQ KKV E E 337
Cdd:TIGR03423 169 --- L E R LE P --- AN Y AGG D Y IGKS G IEK Y YED E L R G KPGYREVEVNAR G RV IRT LSRVPPVP G KD L V LT I D AR LQ QAA E K 242
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 338 S L EKN lrafhssepmmd R AF VV M M N P KN G Q IL S M agkki V NK --------- DG VMQ i E DY AL ----------- GTMTSS Y 397
Cdd:TIGR03423 243 A L GGR ------------ R GA VV V M D P RT G E IL A M ----- V ST psfdpnlfv DG ISS - K DY KA llndpdrplln RAIQGV Y 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 398 EL GST V K GATL L SGYQAEA I K P F T HFFD a P M YF KGSTKPKKS WK D -- F G DI D DLR A LQV S SN VY MFNTV L KM a GI N yvpn 475
Cdd:TIGR03423 305 PP GST F K PVVA L AALEEGV I T P E T RIYC - P G YF QLGGRRFRC WK R gg H G RV D LRK A IEE S CD VY FYQLA L RL - GI D ---- 378
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 476 npldikqetfn K MRY Y FRQ FG L G VS TGIDLP N E SI G QMG --------- RTDNI PG FL L DYA IGQ - Y DTY TPLQLA QYIST 545
Cdd:TIGR03423 379 ----------- K IAE Y AKR FG F G QK TGIDLP G E KS G LVP srewkrkrf GQPWY PG DT L NVS IGQ g Y VLV TPLQLA VATAA 447
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 546 I ANGG YRM KP QI V QE I REQ pnrped V G K V I R SI E SV VL NRVDMDTSYINH V K EG F R R V FQEAD GT GTGTFK GLPYK P AGK 625
Cdd:TIGR03423 448 L ANGG KLY KP HL V KS I EDP ------ D G G V V R RT E PE VL RPLPISPENLDV V R EG M R D V VNGPG GT ARRARL GLPYK M AGK 521
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1258586900 626 TGTA ET V ygges DIGRD E N Y NRKKC - YN L T ---- LAGY APYD a D P EV A FS V V vpw V NNDKS G VNS A -- I GKE I L DAY FD 697
Cdd:TIGR03423 522 TGTA QV V ----- SLKQG E K Y DAEQI p ER L R dhal FVAF APYD - N P KI A VA V I --- V EHGGG G SSA A ap I ARK I M DAY LL 591
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
356-693
3.19e-67
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 223.45
E-value: 3.19e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 356 AFV V MMN PK N G QI L S M A GK KIVNKD G vm Q I EDYALGTM TS S YE L GST V K GA T L L SGYQAEAI KP FTHF FD A P MYFK G S t K 435
Cdd:pfam00905 1 GSA V VLD PK T G EV L A M V GK PSYDPN G -- F I GPLRNRAV TS R YE P GST F K PF T A L AALDNGVL KP DETI FD W P GKQQ G G - K 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 436 PKKS W K - D FGD I DD LR - AL QV SSN V YM FNTVL K M aginyvpnn PL D ikqetfn K M R Y Y FRQ FG L G VS TGI D LP N E SI G QM 513
Cdd:pfam00905 78 SIGD W N q D QVG I GT LR q AL EY SSN W YM QKLAQ K L --------- GA D ------- K L R S Y LKK FG Y G NK TGI G LP G E NA G YL 141
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 514 GRTD n IP G FLLDYA IG qy D T Y TPLQ L AQ YIST IANGG YRMK P QI V QE I REQPNRPEDVGKV I RS iesvvlnrvdmdt S YI 593
Cdd:pfam00905 142 TPYW - LE G ATASFG IG -- L T I TPLQ Q AQ AYAA IANGG KLVP P HL V KS I EDKVDPKVLNKLP I SK ------------- S TA 205
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 594 NH VK EGF R R V fq EA DGTGTGT FKGLP YK P AGKTGTA ETV yggesdi G RDENYNRKKCYNLTLA GYAP Y D a D P EV AF S V VV 673
Cdd:pfam00905 206 EK VK DML R L V -- VN DGTGTGT AAVPG YK V AGKTGTA QVA ------- G PKGGGYYDGAQIGWFV GYAP A D - N P KY AF A V LI 275
330 340
....*....|....*....|.
gi 1258586900 674 PWVNNDKS G VNS A - I G K E IL D 693
Cdd:pfam00905 276 DDPKRYYG G KVA A p I F K D IL E 296
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
21-713
5.30e-42
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 162.25
E-value: 5.30e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 21 R LN V L F FIVF LL FSAI I IQ L GKV QI IDGET Y RNEV N KKEDVT V STPVP RG KMF DR E G KVIVN N kpl RT V t Y T kmkgvdsk 100
Cdd:PRK10795 21 R AL V A F LGIL LL TGVL I AN L YNL QI VRFTD Y QTRS N ENRIKL V PIAPS RG IIY DR N G TPLAL N --- RT I - Y Q -------- 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 101 evlkvarelagl I EM SQ E DM D K L TE T dkkdfwmq L NEK R AAEKV T KA D ESK FRK qeiegkeldkkv E EL R RE R I T Q eelk 180
Cdd:PRK10795 89 ------------ L EM MP E KV D N L QQ T -------- L DAL R SVVDL T DD D IAA FRK ------------ E RA R SR R F T S ---- 132
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 181 elskddlev LAI K SKMN tgykmtpqivkk D V SQNEY A IVSE R L asl PGV DTTVDWE R E YP NDKI L RSIL G S VS NE N ---- 256
Cdd:PRK10795 133 --------- IPV K TNLT ------------ E V QVARF A VNQY R F --- PGV EVKGYQR R Y YP YGSA L THVI G Y VS KI N dkdv 188
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 257 E G L PR E QL eyyl VRD Y NRNDR IGK SY IE KQ YED A LHG MKEQSRNITDKA G NI IR TEKVTEGKS G NNLM LT V D MD LQ KKV E 336
Cdd:PRK10795 189 E R L DK E GK ---- LAN Y AATHD IGK LG IE RY YED V LHG KTGYEEVEVNNR G RV IR QLHEQPPQA G HDIY LT L D LK LQ QYI E 264
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 337 ES L EKN lrafhssepmmd RA F VV MMN P KN G Q IL SMAGKK ---------- I VN KD -- G VMQIEDYA L GTMTSS -- Y ELG ST 402
Cdd:PRK10795 265 TL L AGS ------------ RA A VV VTD P RT G G IL ALVSTP sydpnlfvdg I SS KD ys G LLNDPNRP L INRATQ gv Y PPA ST 332
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 403 VK GATLL S GYQ A EA I KPF T HF FD a P MYFK -- GS T K PKKS WK DF G D -- IDDLRA L QV S SNVYMFNTVLK M a GI N yvpnnpl 478
Cdd:PRK10795 333 VK PYVAV S ALS A GV I TRN T SL FD - P GWWQ lp GS E K RYRD WK KW G H gr LNVTKS L EE S ADTFFYQVAYD M - GI D ------- 403
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 479 dikqetfn KMRYYFRQ FG L G VS TGIDL PN E SI G Q M G -------------- RT D N IP gflld YA IGQ - Y D T Y TP L Q LAQYI 543
Cdd:PRK10795 404 -------- RLSEWMGK FG Y G HY TGIDL AE E RS G N M P trewkqkrfkkpwy QG D T IP ----- VG IGQ g Y W T A TP I Q MSKAL 470
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 544 S T IA N G G YRMK P QIVQEIR E Q pnrpedv GK VIRSIESVVLNRV D MDTS Y INHV K E G FRR V FQEAD GT GTGT F KGL PYK P A 623
Cdd:PRK10795 471 M T LI N D G IVKV P HLLMSTA E D ------- GK QVPWVQPHEPPVG D IHSG Y WEIA K D G MYG V ANRPN GT AHKY F ASA PYK I A 543
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 624 G K T GTA E t V Y G gesd IGRD E N YN RK K C ------ YN L TL A g Y APY D a D P E VA FSVVV pwvnn DKS G VNS A I G --- KE ILD a 694
Cdd:PRK10795 544 A K S GTA Q - V F G ---- LKAN E T YN AH K I aerlrd HK L MT A - F APY N - N P Q VA VAIIL ----- ENG G AGP A V G tim RQ ILD - 610
730
....*....|....*....
gi 1258586900 695 YFD L kak RS N ANSV P V E Q P 713
Cdd:PRK10795 611 HIM L --- GD N NTDL P A E N P 626
PBP_dimer
pfam03717 Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of ...
65-311
1.37e-35
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerization. The domain forms a largely disordered 'sugar tongs' structure.
Pssm-ID: 427460 [Multi-domain]
Cd Length: 178
Bit Score: 132.45
E-value: 1.37e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 65 T P V PRG KMF DR E G K V IVN NKP LRTV T Y T KM K GVDSKE v LK V A RE LA G L I e MSQ ED M D kltetdkkdfwmqlnekraaekv 144
Cdd:pfam03717 2 I P A PRG EIY DR N G V V LAT NKP VYSL T I T PS K LKKADA - LK T A LK LA K L L - SNY ED L D ----------------------- 56
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 145 tkadeskfrkqeiegkel D KKVE E LRR eritqeelkelskddlevlaiks KMN TGYKMT P QIV KK DV S QN E Y A IVS E R L A 224
Cdd:pfam03717 57 ------------------ D EDLT E RFL ----------------------- KMN SYKSYY P VVI KK NL S EE E V A RIE E N L L 95
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 225 S LPGV DTTV D WE R E YP NDKILRSI LG S V SNEN E glpr E Q LE Y YL VRD Y N R N D RI GKS YI EKQYE DA L H G MKEQSRNIT D K 304
Cdd:pfam03717 96 E LPGV SIET D PV R Y YP YGELAAHL LG Y V GEIT E ---- E E LE K YL DKG Y S R G D LV GKS GL EKQYE SV L R G KDGVRQVEV D A 171
....*..
gi 1258586900 305 A G NI IR T 311
Cdd:pfam03717 172 L G RV IR E 178
MrcB
COG0744 Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
326-630
6.20e-23
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain]
Cd Length: 630
Bit Score: 103.85
E-value: 6.20e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 326 T V D MD LQK KV E ESLEKN L RA fhs SE P MMDR A FV V MMN PK N G QI L S M A G KKIVN K DGV mqie DY A LGTM tss YEL GST V K G 405
Cdd:COG0744 300 T L D PK LQK AA E KAVKNV L PE --- GK P GGLQ A AL V VVD PK T G EV L A M V G GRDYG K SQF ---- NR A TQAK --- RQP GST F K P 369
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 406 ATLLSGYQ a EAIK P F T HFF D A P MY F K G ST - K PK KSWKDF - G DIDDLR AL QV S S N VYMFNTVLKM a G INY V pnnpldik QE 483
Cdd:COG0744 370 FVYAAALE - QGYT P A T TVD D E P VT F P G GG w S PK NYDGRY r G PVTLRE AL AN S L N TPAVRLAQEV - G LDK V -------- VD 439
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 484 T FNKM ryyfrqfgl G VSTGI D l PN E S I gqmgrtdnipgflldy A I G QYDT y T PL QL A QYIS T I ANGG YRMK P QIVQEIRE 563
Cdd:COG0744 440 T ARRL --------- G ITSPL D - PN P S L ---------------- A L G TSEV - S PL EM A SAYA T F ANGG VYVE P HAITKVTD 492
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1258586900 564 Q pnrped V GKV IRSIESVVLNRVDMDTS Y I nh VKEGFRR V FQE ad GTG TG - TFK G L P Y kp AGKTGT AE 630
Cdd:COG0744 493 A ------ D GKV LYEAKPKCEQVISPEVA Y L -- MTDMLQD V VTS -- GTG RA a RLP G R P V -- AGKTGT TN 548
PRK15105
PRK15105 peptidoglycan synthase FtsI; Provisional
226-682
1.39e-13
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain]
Cd Length: 578
Bit Score: 74.09
E-value: 1.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 226 LPG VDTTVDWE R E YP NDKILRSIL G SVSNENE G L preqleyylvrdynrndrigk SYI EK QYEDA L H G MKEQSRNIT D KA 305
Cdd:PRK15105 155 LPG IHLREESR R Y YP SGEVTAHLI G FTNVDSQ G I --------------------- EGV EK SFDKW L T G QPGERIVRK D RY 213
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 306 G NI I RTEKV T EGKSGN NL M L TV D MD LQ KK V EES L e K N LR AF HSS E pmmd RAFV V MMNPKN G QI L S MA GKKIV N KDGVMQI 385
Cdd:PRK15105 214 G RV I EDISS T DSQAAH NL A L SI D ER LQ AL V YRE L - N N AV AF NKA E ---- SGSA V LVDVNT G EV L A MA NSPSY N PNNLSGT 288
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 386 EDY A L -- GTM T SSY E L GSTVK GATLLSGY Q AEAI K PFTHFFDA P MYFK G stkpk KSW KD FGDIDD L R --- A LQ V SSNV YM 460
Cdd:PRK15105 289 PKD A M rn RAI T DVF E P GSTVK PMVVMTAL Q RGVV K ENSVLNTV P YRIN G ----- HEI KD VARYSE L T ltg V LQ K SSNV GV 363
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 461 FNTV L K M aginyv P NNP L dik QE T FNK mryyfrq FGLG VS T GID L PN E SI G --- Q MG R TDN I PGFLLDYAI G Q yd TY TPL 537
Cdd:PRK15105 364 SKLA L A M ------ P SSA L --- VD T YSR ------- FGLG KA T NLG L VG E RS G lyp Q KQ R WSD I ERATFSFGY G L -- MV TPL 425
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 538 QLA QYIS TI ANG G - YR ------ MK P QIVQ E ireqpn R -- PE DVGK - V IRSI ESV V L nrvdmdtsyinhvkegfrrvfqe A 607
Cdd:PRK15105 426 QLA RVYA TI GSY G i YR plsitk VD P PVPG E ------ R vf PE SIVR t V VHMM ESV A L ----------------------- P 476
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1258586900 608 D G T G T - GTF KG lp Y KP A G KTGTA ET V yggesdi G R D EN Y - N RKKC Y N ltl AG Y AP y DAD P EV A FS VV vpw V N NDKS G 682
Cdd:PRK15105 477 G G G G V k AAI KG -- Y RI A I KTGTA KK V ------- G P D GR Y i N KYIA Y T --- AG V AP - ASQ P RF A LV VV --- I N DPQA G 537
PBP_1a_fam
TIGR02074 penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ...
320-682
2.02e-10
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain]
Cd Length: 531
Bit Score: 63.82
E-value: 2.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 320 G NN L M ------- L T V D M D L QK KV E ES L EKN LR - A FHSSEPMMDR A F V VM m N P KN G QILSMA G KKIVN K DGV mqie DY A LG 391
Cdd:TIGR02074 214 G EE L Y tgglkiy T T L D L D A QK AA E KV L NTG LR v A GRRDGDDLQA A L V AI - D P DT G AVRALV G GRDYG K SQF ---- NR A TQ 288
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 392 TMTSS yel GST V K ---- G A T L LS G Y qaeai K P F T HFF D A P MYFK G ST -- K PK K - SWKDF G DIDDLR AL QV S S N VYMFNTV 464
Cdd:TIGR02074 289 AKRQP --- GST F K pfvy A A A L EK G L ----- T P A T IVN D E P ITYN G NG pw S PK N y GGGYR G NVTLRQ AL AQ S R N IPAVRLL 360
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 465 LKM aginyvpnnpldikqetfnkmryyfrqfglgvst G I D LPNESIGQM G R T DNIP g FL L DY A I G QYDT y T PL QL A QYIS 544
Cdd:TIGR02074 361 QEV ---------------------------------- G L D KVVALAKRF G I T SPLD - PV L SL A L G TVEV - S PL EM A SAYA 404
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 545 TI ANGG YRMK P QIVQE I REQP nrpedv GKVI RSIESVVLNRVDMD T S YI nh VKEGFRR V FQ eadg T GTG TFKG LP YK P - A 623
Cdd:TIGR02074 405 VF ANGG KYVE P HGIRK I VDRD ------ GKVI YENKPKTTQVISPA T A YI -- MTDMLKG V VE ---- S GTG RSAR LP GR P v A 472
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1258586900 624 GKTGT aetvygge SDIG RD ENY nrkkcynltl A GY A PY dadpeva FSVV V p WV NN D KSG 682
Cdd:TIGR02074 473 GKTGT -------- TQNW RD AWF ---------- V GY T PY ------- YVTA V - WV GY D DKK 505
MrcA
COG5009 Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
356-628
1.22e-07
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain]
Cd Length: 785
Bit Score: 55.17
E-value: 1.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 356 A F V VM m N P KN G QI L SMA G kkivnkdgvmqiedyal G tmt SSY E L ------------- GS TV K ---- G A T L LS GY QAEA I k 418
Cdd:COG5009 424 A L V AL - D P HT G AV L ALV G ----------------- G --- FDF E Q skfnratqakrqp GS SF K pfvy A A A L DN GY TPAT I - 481
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 419 pfth FF DAP MY F KGST ----- K PK KSWKD F - G DID d LR - AL QV S S N V y M fn TV -- L KMA GI N YV pnnpld I K qetfnkmr 489
Cdd:COG5009 482 ---- IN DAP IV F DDGG gggvw R PK NYSGK F y G PTT - LR e AL EK S R N L - V -- TV rl L QDV GI D YV ------ I D -------- 539
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 490 y Y FRQ FG L gvstgidlpnesigqmgr TDNI P GF L - L dy A I G QYDT y TPL QL A QYISTI ANGGYR MK P QIVQE I ------- 561
Cdd:COG5009 540 - Y AER FG I ------------------ YSKL P PN L s L -- A L G SGEV - TPL EM A RAYAVF ANGGYR VE P YLIDR I edrngkv 597
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1258586900 562 -- R EQ P N R PEDVGKVIRSIESVVLNR ------ V D MD T S Y - INHVKE G frr V F Q E ad GTG TGT f KG L PYKP AGKTGT 628
Cdd:COG5009 598 iy R AD P A R ACEDCDAAEWDGAEPRLP dpaeqv I D PR T A Y q MTSMLR G --- V V Q R -- GTG RRA - RA L GRDI AGKTGT 667
V_ATP_synt_G
TIGR01147 vacuolar ATP synthase, subunit G; This model describes the vacuolar ATP synthase G subunit in ...
137-224
3.09e-03
vacuolar ATP synthase, subunit G; This model describes the vacuolar ATP synthase G subunit in eukaryotes and includes members from diverse groups e.g., fungi, plants, parasites etc. V-ATPases are multi-subunit enzymes composed of two functional domains: A transmembrane Vo domain and a peripheral catalytic domain V1. The G subunit is one of the subunits of the catalytic domain. V-ATPases are responsible for the acidification of endosomes and lysosomes, which are part of the central vacuolar system. [Energy metabolism, ATP-proton motive force interconversion]
Pssm-ID: 130217 [Multi-domain]
Cd Length: 113
Bit Score: 37.89
E-value: 3.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258586900 137 EKRAAEKV TK A DES K FRKQEIEGK E LD K K VE ELRRE R it QE E L KE LSKDD L E - VL A IKS K MNTGYKMTPQIV KK D V SQ N E 215
Cdd:TIGR01147 15 EKRAAEKV SE A RKR K TKRLKQAKE E AQ K E VE KYKQQ R -- EK E F KE FEAKH L G g NG A AEE K AEAETQAKIREI KK A V QK N K 92
....*....
gi 1258586900 216 Y A IVSER L A 224
Cdd:TIGR01147 93 D A VIKDL L H 101
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
