|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
3-975 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 761.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 3 RLTKFSLKNRAAIIIMVFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDGII 82
Cdd:COG0841 2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYIT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 83 SSTHEGLSRIDIAYTSKANMKDAAREVEKAINTIK--LPKDVTKPVVSQLNTSMIPLAQITIQKqngfSKADEKQI---- 156
Cdd:COG0841 82 STSSEGSSSITVEFELGTDIDEALVDVQNAVDRARsdLPEDVEPPGVTKVNPSDFPVMVLALSS----DDLDELELsdya 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 157 EKEIVPQLESIDGVANVMFFGKSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKEEYNLRVIGEVKNI 236
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 237 NEIKNITVA----PQVKLQDIAQIELK-QNYDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQFSIK 311
Cdd:COG0841 238 EEFENIVIRtndgSVVRLGDVARVEDGaEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELT 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 312 LLASTHEQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGR 391
Cdd:COG0841 318 IVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGI 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 392 LVDDSIVVIENIFRRLQKEPFSKDIIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILSSLIVA 471
Cdd:COG0841 398 VVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVA 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 472 LTVVPLMAFLLLKKTKHRKPSSSPR------------YVATLKWALSHKFIILLTSFLLFAGSIAAYILLPKSNIKSEDD 539
Cdd:COG0841 478 LTLTPALCARLLKPHPKGKKGRFFRafnrgfdrltrgYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQ 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 540 TMLSVNMTFPADYNSESQKQKAFDFEKKLLSNPDVTDVILRMGSSaedaqwGQTTKNNLASIFVVFKKGS----NIDQYI 615
Cdd:COG0841 558 GQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFS------GGGSGSNSGTIFVTLKPWDerdrSADEII 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 616 KDLKKDHKSFEPAELDYIKTSYSSSGGGNNLQFNVTATNETNLKKAANIVETKLKSMDALSKVKTNLEDSKKEWQIHIDQ 695
Cdd:COG0841 632 ARLREKLAKIPGARVFVFQPPAGGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDR 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 696 TKAEQLGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMIEHKKENINKQTDILNANILSPINGPIPLKDIATISEKQLQ 775
Cdd:COG0841 712 EKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGP 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 776 TEIFHKDGKETIQITAE-ASSEDLSKVSAEVNNAITNLDLPSGAKVNIAGATESMQENFTDLFKIMGIAIGIVYLIMVIT 854
Cdd:COG0841 792 SSINRYNGQRSVTVSANlAPGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQ 871
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 855 FGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIERVQQNRENGMETRDALLEAGSTRL 934
Cdd:COG0841 872 FESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLRL 951
|
970 980 990 1000
....*....|....*....|....*....|....*....|.
gi 1258771808 935 RPIIMTAVTTIVAMLPLLFGQSqAGSMVSKSLAVVVIGGLA 975
Cdd:COG0841 952 RPILMTSLATILGLLPLALGTG-AGAEFRQPLGIAVIGGLL 991
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
6-974 |
2.89e-171 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 528.02 E-value: 2.89e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 6 KFSLKNRAAIIIMVFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDGIISST 85
Cdd:pfam00873 3 KFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSSQS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 86 HEGLSRIDIAYTSKANMKDAAREVEKAIN--TIKLPKDVTKPVVSQLNTSMIPLAQITIQKQNGFSKADEKQ--IEKEIV 161
Cdd:pfam00873 83 SYGLSSITLTFELGTDIDIARQDVQNRLQlaTPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRdyADTNIK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 162 PQLESIDGVANVMFFGKSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKEEYNLRVIGEVKNINEIKN 241
Cdd:pfam00873 163 PQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDFEK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 242 ITVAPQ----VKLQDIAQIEL-KQNYDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQFSIKLLAST 316
Cdd:pfam00873 243 IIVKNQdgspVRLRDVATVELgSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVVYDT 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 317 HEQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRLVDDS 396
Cdd:pfam00873 323 TPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDA 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 397 IVVIENIFRRLQKEPFSK-DIIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILSSLIVALTVV 475
Cdd:pfam00873 403 IVVVENIERVLEENGLKPlEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALTLT 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 476 PLMAFLLLKKTKHRKP------------SSSPRYVATLKWALSHKFIILLTSFLLFAGSIAAYILLPKSNIKSEDDTMLS 543
Cdd:pfam00873 483 PALCATLLKPRREPKHggffrwfnrmfdRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFV 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 544 VNMTFPA----DYNSESQKQkafdFEKKLLSNPDVTDVILRMGSSAEdaqwGQTTKNNLASIFVVFK-----KGSN--ID 612
Cdd:pfam00873 563 TSAQLPPgvslDQTQRVMKQ----VEKILKEKPEVESVFAVTGFAFS----GDNNGPNSGDAFISLKpwkerPGPEksVQ 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 613 QYIKDLKKDHKSFEPAEL---DYIKTSYSSSGGGNNLQFNVTATNETN--LKKAANIVETKLKSMDALSKVKTNLEDSKK 687
Cdd:pfam00873 635 ALIERLRKALKQIPGANVflfQPIQLRGLGTISGFRSDLQVKIFGDDLdaLDEARNQILAALAQLPGLSDVRSDGQEDQP 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 688 EWQIHIDQTKAEQLGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMIEHKKENINKQTDILNANILSPINGPIPLKDIA 767
Cdd:pfam00873 715 QLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFA 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 768 TISEKQLQTEIFHKDGKETIQITAEASSED-LSKVSAEVNNAITNLDLPSGAKVNIAGATESMQENFTDLFKIMGIAIGI 846
Cdd:pfam00873 795 KIEWGYGPPSINRYNGFRSIVISGNVAAGDsLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLV 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 847 VYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIE-RVQQNRENGMETRDA 925
Cdd:pfam00873 875 VFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEfANELREQEGKSLEEA 954
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*....
gi 1258771808 926 LLEAGSTRLRPIIMTAVTTIVAMLPLLFGQSqAGSMVSKSLAVVVIGGL 974
Cdd:pfam00873 955 ILEACRLRLRPILMTALAAILGVLPLALSTG-AGSELQQPLGIVVFGGL 1002
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-974 |
4.11e-144 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 456.80 E-value: 4.11e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 1 MDRLTKFSLKNRAAIIIMVFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDG 80
Cdd:COG3696 2 LNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 81 IISSTHEGLSRIDIAYTSKANMKDAAREVEKAINTIK--LPKDVTkPVVSQLNTSMIPLAQITIQ-KQNGFSKADEKQIE 157
Cdd:COG3696 82 VRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVReqLPAGVT-PELGPISTGLGEIYQYTLEsDPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 158 K-EIVPQLESIDGVANVMFFGKSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKEEYNLRVIGEVKNI 236
Cdd:COG3696 161 DwVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 237 NEIKNITVAPQ----VKLQDIAQIElkqnydtISH--------INGE-EGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQ 303
Cdd:COG3696 241 EDIENIVVKTRngtpVLLRDVAEVR-------IGPaprrgaatLNGEgEVVGGIVLMLKGENALEVIEAVKAKLAELKPS 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 304 YKDQFSIKllaSTHEQ---VENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNIL 380
Cdd:COG3696 314 LPEGVKIV---PFYDRsdlIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLM 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 381 TLGGLAVAVGRLVDDSIVVIENIFRRLQKEPFSK------DIIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLML 454
Cdd:COG3696 391 SLGGLAIDFGIIVDGAVVMVENILRRLEENRAAGtprerlEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFR 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 455 PMVLAVVYSILSSLIVALTVVPLMAFLLLKKTKHRKPS-----SSPRYVATLKWALSHKFIILLTSFLLFAGSIAAYILL 529
Cdd:COG3696 471 PMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKENplvrwLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRL 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 530 PKSNIKSEDDTMLSVNMTFPADYNSESQKQKAFDFEKKLLSNPDVTDVILRMGSS--AEDAqWGQttknNLASIFVVFK- 606
Cdd:COG3696 551 GSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAedATDP-MGV----NMSETFVILKp 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 607 -----KGSNIDQYIKDLKKDHKSFEPAELD---YIKTSYS--SSGG---------GNNLQFnvtatnetnLKKAANIVET 667
Cdd:COG3696 626 rsewrSGRTKEELIAEMREALEQIPGVNFNfsqPIQMRVDelLSGVradvavkifGDDLDV---------LRRLAEQIEA 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 668 KLKSMDALSKVKTNLEDSKKEWQIHIDQTKAEQLGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMIEHKKENINKQTD 747
Cdd:COG3696 697 VLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEA 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 748 ILNANILSPINGPIPLKDIATISEKQLQTEIFHKDGKETIQITAEASSEDLSKVSAEVNNAI-TNLDLPSGAKVNIAGAT 826
Cdd:COG3696 777 IRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVaEQVKLPPGYYIEWGGQF 856
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 827 ESMQENFTDLFKIMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAI 906
Cdd:COG3696 857 ENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGV 936
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1258771808 907 VLIERVQQNRENGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGQSqAGSMVSKSLAVVVIGGL 974
Cdd:COG3696 937 VLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTG-PGSEVQRPLATVVIGGL 1003
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
13-993 |
6.77e-131 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 421.35 E-value: 6.77e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 13 AAIIIMvFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDGIISSTHEGLSRI 92
Cdd:NF033617 10 ATLLLS-LLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 93 DIAYTSKANMKDAAREVEKAINTIK--LPKDVTKPVV-SQLNTSMIPLAQITIQKQNGFSKADEKQIEKEIVPQLESIDG 169
Cdd:NF033617 89 TLQFRLGTDLDVALSEVQAAINAAQslLPSEAPDPPVyRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLAPKLSQING 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 170 VANVMFFGKSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKEEYNLRVIGEVKNINEIKNITVAPQ-- 247
Cdd:NF033617 169 VGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYAdn 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 248 ---VKLQDIAQIEL-KQNYDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQFSIKLLASTHEQVENA 323
Cdd:NF033617 249 gapVRLGDVATVELgAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFIRAS 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 324 VTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRLVDDSIVVIENI 403
Cdd:NF033617 329 IDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVENI 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 404 FRRLQ--KEPFSKDIIidATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILSSLIVALTVVPLMAFL 481
Cdd:NF033617 409 HRHIEegESPLEAALK--GAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCSR 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 482 LLKktKHRKPSS------------SPRYVATLKWALSHKFIILLTSFLLFAGSIAAYILLPKSNIKSEDDTMLSVNMTFP 549
Cdd:NF033617 487 LLK--ANEKPGRfaravdrffdglTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAP 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 550 ADYNSESQKQKAFDFEKKLLSNPDV--TDVILRMGSSAEDAQwgqttknnlASIFVVFKKGSNID----QYIKDLKKDHK 623
Cdd:NF033617 565 QSISLDYMSAKMRDVEKILSSDPEVqsLTSFNGVGGNPGDNT---------GFGIINLKPWDERDvsaqEIIDRLRPKLA 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 624 SFEPAELDY--IKTSYSSSGGGNNL-QFNVTATNETNLKKAANIVETKLKSMDALSKVKTNLEDSKKEWQIHIDQTKAEQ 700
Cdd:NF033617 636 KVPGMDLFLfpLQDLPGGAGSSLPQyQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAAR 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 701 LGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMIEHKKENINKQTDILNANILSPINGPIPLKDIATISEKQLQTEIFH 780
Cdd:NF033617 716 LGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNH 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 781 KDGKETIQITAE-ASSEDLSKVSAEVNNAITNLdLPSGAKVNIAGATESMQENFTDLFKIMGIAIGIVYLIMVITFGQAR 859
Cdd:NF033617 796 FNQFNSATLSFNlAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFV 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 860 APFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIE-RVQQNRENGMETRDALLEAGSTRLRPII 938
Cdd:NF033617 875 DPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEfANELQRHQGLSRREAIYQAAALRLRPIL 954
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*
gi 1258771808 939 MTAVTTIVAMLPLLFGqSQAGSMVSKSLAVVVIGGLAVSTVLTLVVVPVMYELLD 993
Cdd:NF033617 955 MTTLAMLLGAIPLMLS-TGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLA 1008
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-974 |
4.62e-91 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 313.62 E-value: 4.62e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 1 MDRLTKFSLKNRAAIIIMVFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDG 80
Cdd:TIGR00914 2 IERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 81 IISSTHEGLSRIDIAYTSKANMKDAAREVEKAINTI--KLPKDVTkPVVSQLNTSMIPLAQITIQKQNGFSKADE----- 153
Cdd:TIGR00914 82 TRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQArdNLPEGVS-PEMGPISTGLGEIFLYTVEAEEGARKKDGgaytl 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 154 ---KQIEKEIV-PQLESIDGVANVMFFGKSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKEEYNLRV 229
Cdd:TIGR00914 161 tdlRTIQDWIIrPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 230 IGEVKNINEIKNITVAPQ----VKLQDIAQIELKQNYDT-ISHINGEE---GTGLIIMkepSKNAVAIGKEIDKKIKDIS 301
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGegvpIRIRDVARVQIGKELRTgAATENGKEvvlGTVFMLI---GENSRTVAQAVGDKLETIN 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 302 KQYKDQFSIKLLASTHEQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILT 381
Cdd:TIGR00914 318 KTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMS 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 382 LGglAVAVGRLVDDSIVVIENIFRRLQK------EPFSKD----IIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGK 451
Cdd:TIGR00914 398 LG--ALDFGLIVDGAVVIVENAHRRLAEaqhhhgRQLTLKerlhEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGK 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 452 LMLPMVLAVVYSILSSLIVALTVVP-LMAFLLLKKTKHRK----PSSSPRYVATLKWALSHKFIILLTSFLLFAGSIAAY 526
Cdd:TIGR00914 476 MFHPMAFTVVLALAGAMILSLTFVPaAVALFIRGKVAEKEnrlmRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIA 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 527 ILLPKSNIKSEDDTMLSVN-MTFPADYNSESQKQKAfDFEKKLLSNPDVTDVILRMGsSAEDAQwgQTTKNNLASIFVVF 605
Cdd:TIGR00914 556 SRVGGEFIPSLNEGDLAYQaLRIPGTSLAQSVAMQQ-TLEKLIKSFPEVARVFAKTG-TAEIAT--DPMPPNASDTYIIL 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 606 K--------KGSNIDQYIKDLKKDHK----SFEPAELDYIKTSYSSSGGGNNLQFNVTATNETNLKKAANIVETKLKSMD 673
Cdd:TIGR00914 632 KpesqwpegKKTKEDLIEEIQEATVRipgnNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVP 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 674 ALSKVKTNLEDSKKEWQIHIDQTKAEQLGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMI---EHKKENIN--KQTDI 748
Cdd:TIGR00914 712 GAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIrlpESLRESPQalRQLPI 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 749 LNANILSPINGPIPLKDIATISEKQLQTEIFHKDGKETIQITAEASSEDLSKVSAEVNNAITN-LDLPSGAKVNIAGATE 827
Cdd:TIGR00914 792 PLPLSEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEqVKLPPGYWITWGGQFE 871
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 828 SMQENFTDLFKIMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIV 907
Cdd:TIGR00914 872 QLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLV 951
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1258771808 908 LIERVQQNRENGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGqSQAGSMVSKSLAVVVIGGL 974
Cdd:TIGR00914 952 MISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIA-TGTGAEVQRPLATVVIGGI 1017
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
14-974 |
7.93e-80 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 282.00 E-value: 7.93e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 14 AIIIMvflisILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDGIIS-STHEGLSRI 92
Cdd:TIGR00915 16 AIIIM-----LAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSsSDSDGSMTI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 93 DIAYTSKANMKDAAREVEKAIN--TIKLPKDVTKPVVSQLNTSMIPLAQITIQKQNGFSKADE--KQIEKEIVPQLESID 168
Cdd:TIGR00915 91 TLTFEQGTDPDIAQVQVQNKLQlaTPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDlsDYAASNMVDPLSRLE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 169 GVANVMFFGkSTSELSIVLDPNKLKDKNVT--------SEQVLKVVQGKETSTPTgaitVNKEEYNLRVIGE--VKNINE 238
Cdd:TIGR00915 171 GVGDVQLFG-SQYAMRIWLDPAKLNSYQLTpadvisaiSAQNAQISAGQLGGLPA----VPGQQLNATIIAQtrLQTPEQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 239 IKNITV-----APQVKLQDIAQIEL-KQNYDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQFSIKL 312
Cdd:TIGR00915 246 FENILLkvntdGSQVRLKDVARVELgGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQGMKYVY 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 313 LASTHEQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRL 392
Cdd:TIGR00915 326 PYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLL 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 393 VDDSIVVIENIFRRLQKEPFSKdiiIDATK----EVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILSSL 468
Cdd:TIGR00915 406 VDDAIVVVENVERVMAEEGLPP---KEATRksmgQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 469 IVALTVVPLMAFLLLKKTKHRKP----------------SSSPRYVATLKWALSHKFIILLTSFLLFAGSIAAYILLPKS 532
Cdd:TIGR00915 483 LVALILTPALCATMLKPIEKGEHhekkggffgwfnrmfdSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPTS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 533 NIKSEDDTMLSVNMTFPADYNSEsQKQKAFD-FEKKLLSNP--DVTDVILRMGSSAedAQWGQttknNLASIFVVFK--- 606
Cdd:TIGR00915 563 FLPDEDQGVFMTIVQLPAGATAE-RTQAVLAqVTKYLLAKEkaNVESVFTVNGFSF--AGRGQ----NMGMAFIRLKdwe 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 607 ----KGSNIDQYIKDLKKDHKSFE-----PAELDYIKTSYSSSGGGNNLQFNVTATNETnLKKAANIVETKLKSMDALSK 677
Cdd:TIGR00915 636 ertgKENSVFAIAGRATGHFMQIKdamviAFVPPAILELGNATGFDFFLQDRAGLGHEA-LLQARNQLLGLAAQNPALTR 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 678 VKTNLEDSKKEWQIHIDQTKAEQLGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMIEHKKENINKQTDILNANILSPI 757
Cdd:TIGR00915 715 VRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNAS 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 758 NGPIPLKDIATISEKQLQTEIFHKDGKETIQITAEASSedlSKVSAEVNNAITNL--DLPSGAKVNIAGAteSMQENFT- 834
Cdd:TIGR00915 795 GEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAP---GVSTGQAMAAMEAIaqKLPPGFGFSWTGM--SYEERLSg 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 835 -DLFKIMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIERVQ 913
Cdd:TIGR00915 870 sQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAK 949
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1258771808 914 QNRENGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGqSQAGSMVSKSLAVVVIGGL 974
Cdd:TIGR00915 950 ELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAIS-TGAGSGSQHAIGTGVFGGM 1009
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
14-974 |
1.39e-77 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 275.07 E-value: 1.39e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 14 AIIIMVFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDGIISSTHEGLSRID 93
Cdd:PRK10614 13 ATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRII 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 94 IAYTSKANMKDAAREVEKAINTIK--LPKDV-TKPVVSQLNTSMIPLAQITIQKQNgFSKADEKQI-EKEIVPQLESIDG 169
Cdd:PRK10614 93 LQFDFDRDINGAARDVQAAINAAQslLPSGMpSRPTYRKANPSDAPIMILTLTSDT-YSQGQLYDFaSTQLAQTISQIDG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 170 VANVMFFGKSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKEEYNLRVIGEVKNINEIKNITV----- 244
Cdd:PRK10614 172 VGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLIIhynng 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 245 APqVKLQDIAQIELK-QNYDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKD--------ISKQYKDQFSIKLLAS 315
Cdd:PRK10614 252 AA-VRLGDVATVTDSvQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPElretipaaIDLQIAQDRSPTIRAS 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 316 THEqVENAVtsmgkevilgAIAATLIILI---FLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRL 392
Cdd:PRK10614 331 LEE-VEQTL----------AISVALVILVvflFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 393 VDDSIVVIENIFRRLQKEPFSKDIIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILSSLIVAL 472
Cdd:PRK10614 400 VDDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 473 TVVPLMAFLLLkktKHRKPSSSPR--------------YVATLKWALSHKFIILLTSFLLFAGSIAAYILLPKSNIKSED 538
Cdd:PRK10614 480 TLTPMMCAWLL---KSSKPREQKRlrgfgrmlvalqqgYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQD 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 539 DTMLsvnMTF-PADYNSESQ--KQKAFDFEKKLLSNPDVTDVILRMGSSaedaqwgqttKNNLASIFVVFK----KGSNI 611
Cdd:PRK10614 557 TGRL---MGFiQADQSISFQamRGKLQDFMKIIRDDPAVDNVTGFTGGS----------RVNSGMMFITLKplseRSETA 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 612 DQYIKDLKKDHKSFEPAELDYIKTSYSSSGG---GNNLQFNVTATNETNLKKAANIVETKLKSMDALSKVKTNLEDSKKE 688
Cdd:PRK10614 624 QQVIDRLRVKLAKEPGANLFLMAVQDIRVGGrqsNASYQYTLLSDDLAALREWEPKIRKALAALPELADVNSDQQDKGAE 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 689 WQIHIDQTKAEQLGLTPELAAQQVAFLMKKSPIGEI--SINNEKTTIMIEHKKENinkqtDILNANILSPING---PIPL 763
Cdd:PRK10614 704 MALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIyqPLNQYKVVMEVDPRYTQ-----DISALEKMFVINNegkAIPL 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 764 KDIATISEKQLQTEIFHK--DGKETIQIT-AEASSedLSKVSAEVNNAITNLDLPSGAKVNIAGATESMQENFTDLFKIM 840
Cdd:PRK10614 779 SYFAKWQPANAPLSVNHQglSAASTISFNlPTGKS--LSDASAAIERAMTQLGVPSTVRGSFAGTAQVFQETMNSQLILI 856
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 841 GIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIE-RVQQNRENG 919
Cdd:PRK10614 857 LAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDfALEAQRNGN 936
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*
gi 1258771808 920 METRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGqSQAGSMVSKSLAVVVIGGL 974
Cdd:PRK10614 937 LTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLS-GGDGAELRQPLGITIVGGL 990
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
17-992 |
1.94e-69 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 251.29 E-value: 1.94e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 17 IMVFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDGIISSTHEGLSRIDIAY 96
Cdd:PRK09579 16 VVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSIISIYA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 97 TSKANMKDAAREVEKAINTIK--LPKDVTKPVVSQLNTSMIPLAQITIQKQNGFSKADEKQIEKEIVPQLESIDGVANVM 174
Cdd:PRK09579 96 RIGADSDRLFTELLAKANEVKnqLPQDAEDPVLSKEAADASALMYISFYSEEMSNPQITDYLSRVIQPKLATLPGMAEAE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 175 FFGKSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAItvnKEEYNLRVIG---EVKNINEIKNITVA----PQ 247
Cdd:PRK09579 176 ILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEV---KGEYVVTSINastELKSAEAFAAIPVKtsgdSR 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 248 VKLQDIAQIEL-KQNYDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQFSIKLLASTHEQVENAVTS 326
Cdd:PRK09579 253 VLLGDVARVEMgAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIAYDATLFIQASIDE 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 327 MGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRLVDDSIVVIENIFRR 406
Cdd:PRK09579 333 VVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHRH 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 407 LQ--KEPFskDIIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILSSLIVALTVVPLMAFLLLK 484
Cdd:PRK09579 413 IEegKSPF--DAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMMCALLLR 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 485 KTK------HRK----PSSSPRYVATLKWALSHKFIILLTSFLLFaGSIAAYILLPKSNIKSEDDTMLSVNMT-FPADYN 553
Cdd:PRK09579 491 HEEnpsglaHRLdrlfERLKQRYQRALHGTLNTRPVVLVFAVIVL-ALIPVLLKFTQSELAPEEDQGIIFMMSsSPQPAN 569
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 554 SESQKQKAFDFEKKLLSNPDVTDVILRMGSSAEDA--------QWGQTTKNNLASIFVVFKKGSNIdqyikdlkkdhksf 625
Cdd:PRK09579 570 LDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQSgiggfllkPWNERERTQMELLPLVQAKLEEI-------------- 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 626 ePAELDYIKTSYSSSGGGNNLQFNV---TATNETNLKKAANIVETKLKSMDALSKVKTNLEDSKKEWQIHIDQTKAEQLG 702
Cdd:PRK09579 636 -PGLQIFGFNLPSLPGTGEGLPFQFvinTANDYESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRAKAAQMG 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 703 LTPELAAQQVAFLMKKSPIGEISINNEKTTImIEHKKENINKQTDILNANILSPINGP-IPLKDIATISEKQLQTEI--F 779
Cdd:PRK09579 715 VSMQDLGGTLATLLGEGEINRFTIDGRSYKV-IAQVERPYRDNPGWLNNYYVKNEQGQlLPLSTLITLSDRARPRQLnqF 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 780 HKDGKETIQ-ITAEASSEDLSKVSaevnnAITNLDLPSGAKVNIAGATESMQENFTDLFKIMGIAIGIVYLIMVITFGQA 858
Cdd:PRK09579 794 QQLNSAIISgFPIVSMGEAIETVQ-----QIAREEAPEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFLVLAAQFESF 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 859 RAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIERVQQNR-ENGMETRDALLEAGSTRLRPI 937
Cdd:PRK09579 869 RDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRhEQGLSRREAIEEAAAIRLRPV 948
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*
gi 1258771808 938 IMTAVTTIVAMLPLLFGqSQAGSMVSKSLAVVVIGGLAVSTVLTLVVVPVMYELL 992
Cdd:PRK09579 949 LMTTAAMVFGMVPLILA-TGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLL 1002
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
7-974 |
1.17e-68 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 249.26 E-value: 1.17e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 7 FSLKNRAAIIIMVfLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDGIISSTH 86
Cdd:PRK10503 16 FILRPVATTLLMV-AILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 87 EGLSRIDIAYTSKANMKDAAREVEKAIN--TIKLPKDV-TKPVVSQLN------------TSMIPLAQItiqkqngfska 151
Cdd:PRK10503 95 GGASVITLQFQLTLPLDVAEQEVQAAINaaTNLLPSDLpNPPVYSKVNpadppimtlavtSTAMPMTQV----------- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 152 dEKQIEKEIVPQLESIDGVANVMFFGKSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKEEYNLRVIG 231
Cdd:PRK10503 164 -EDMVETRVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSAND 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 232 EVKNINEIKNITVAPQ----VKLQDIAQIEL-KQNYDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQYKD 306
Cdd:PRK10503 243 QMQSAEEYRQLIIAYQngapIRLGDVATVEQgAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 307 QFSIKLLASTHEQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLA 386
Cdd:PRK10503 323 SVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALT 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 387 VAVGRLVDDSIVVIENIFRRLQKEPFSKDIIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILS 466
Cdd:PRK10503 403 IATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILI 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 467 SLIVALTVVPLMAFLLLKKTKHRKPSSSPR------------YVATLKWALSHKFIILLTSFLLFAGSIAAYILLPKSNI 534
Cdd:PRK10503 483 SAVVSLTLTPMMCARMLSQESLRKQNRFSRasermfdrviaaYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFF 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 535 KSEDDTMLSVNMTFP--ADYNSESQKQKAfdFEKKLLSNPDVTDVILRMGSSaedaqwGQTTKNNLASIFVVFK----KG 608
Cdd:PRK10503 563 PVQDNGIIQGTLQAPqsSSFANMAQRQRQ--VADVILQDPAVQSLTSFVGVD------GTNPSLNSARLQINLKpldeRD 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 609 SNIDQYIKDLKKDHKSF-------EPAELDYIKTSYSSSgggnNLQFNVTATNETNLKKAANIVETKLKSMDALSKVKTN 681
Cdd:PRK10503 635 DRVQKVIARLQTAVAKVpgvdlylQPTQDLTIDTQVSRT----QYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSD 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 682 LEDSKKEWQIHIDQTKAEQLGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMIEHKKENINKQTDILNANILSPINGPI 761
Cdd:PRK10503 711 WQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVV 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 762 PLKDIATISEKQLQTEIFHKDGKETIQITAEASSE-DLSKVSAEVNNAITNLDLPSGAKVNIAGATESMQENFTDLFKIM 840
Cdd:PRK10503 791 PLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGySLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLI 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 841 GIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIE-RVQQNRENG 919
Cdd:PRK10503 871 VAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDfALAAEREQG 950
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*
gi 1258771808 920 METRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGQSqAGSMVSKSLAVVVIGGL 974
Cdd:PRK10503 951 MSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTG-VGAELRRPLGICMVGGL 1004
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
17-974 |
3.31e-60 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 223.94 E-value: 3.31e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 17 IMVFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKqfrNLEHIDGII----SSTHEGLSRI 92
Cdd:PRK10555 14 VLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQ---NMTGLDNLMymssQSSGTGQASV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 93 DIAYTSKANMKDAAREVEKAINTI--KLPKDVTKPVVSQLNTSMIPLAQITIQKQNG-FSKAD-EKQIEKEIVPQLESID 168
Cdd:PRK10555 91 TLSFKAGTDPDEAVQQVQNQLQSAmrKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGsMDKQDiADYVASNIQDPLSRVN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 169 GVANVMFFGkSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAI----TVNKEEYNLRVIGE--VKNINEIKNI 242
Cdd:PRK10555 171 GVGDIDAYG-SQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLggtpSVDKQALNATINAQslLQTPEQFRDI 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 243 TV-----APQVKLQDIAQIEL-KQNYDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQFSIKLLAST 316
Cdd:PRK10555 250 TLrvnqdGSEVTLGDVATVELgAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGLEYKVAYET 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 317 HEQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRLVDDS 396
Cdd:PRK10555 330 TSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLVDDA 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 397 IVVIENIFRRLQKEPFSKDiiiDATK----EVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILSSLIVAL 472
Cdd:PRK10555 410 IVVVENVERIMSEEGLTPR---EATRksmgQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAM 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 473 TVVPLMAFLLLK---KTKHRKPS------------SSPRYVATLKWALSHKFIILLTSFLLFAGSIAAYILLPKSNIKSE 537
Cdd:PRK10555 487 ILTPALCATLLKplkKGEHHGQKgffgwfnrmfnrNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPTSFLPLE 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 538 DDTMLSVNMTFPADYNSESQKQKAFDFEKKLLSNP--DVTDVILRMGSSAEDAqwGQttknNLASIFVVFK-------KG 608
Cdd:PRK10555 567 DRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEkdNVMSVFATVGSGPGGN--GQ----NVARMFIRLKdwderdsKT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 609 SNIDQYIKDLKKDHKSFEPAELdYIKTSYSSSGGGNNLQFNV-----TATNETNLKKAANIVETKLKSMDALSKVKTNLE 683
Cdd:PRK10555 641 GTSFAIIERATKAFNKIKEARV-IASSPPAISGLGSSAGFDMelqdhAGAGHDALMAARNQLLALAAKNPELTRVRHNGL 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 684 DSKKEWQIHIDQTKAEQLG---------LTPELAAQQVAFLMKKSPIGEISINNEKTTIMIehkKENINKQTdILNANil 754
Cdd:PRK10555 720 DDSPQLQIDIDQRKAQALGvsiddindtLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRML---PDDINLWY-VRNKD-- 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 755 spiNGPIPLKDIATISEKQLQTEIFHKDGKETIQITAEASSEDLSKVSAEVNNAITNlDLPSGAKVNIAGAteSMQENFT 834
Cdd:PRK10555 794 ---GGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVK-QLPNGFGLEWTAM--SYQERLS 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 835 --DLFKIMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIERV 912
Cdd:PRK10555 868 gaQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFA 947
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1258771808 913 QQNRENGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGQSqAGSMVSKSLAVVVIGGL 974
Cdd:PRK10555 948 NEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTG-AGSGSQHAVGTGVMGGM 1008
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
14-974 |
6.75e-59 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 220.16 E-value: 6.75e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 14 AIIIMvflisILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKqfrNLEHIDGII----SSTHEGL 89
Cdd:PRK15127 16 AIIIM-----LAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQ---NMNGIDNLMymssNSDSTGT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 90 SRIDIAYTSKANMKDAAREVEK--AINTIKLPKDVTKPVVSQLNTSMIPLAQITIQKQNGFSKADE--KQIEKEIVPQLE 165
Cdd:PRK15127 88 VQITLTFESGTDADIAQVQVQNklQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDisDYVAANMKDPIS 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 166 SIDGVANVMFFGkSTSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAI----TVNKEEYNLRVIGEVK--NINEI 239
Cdd:PRK15127 168 RTSGVGDVQLFG-SQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLggtpPVKGQQLNASIIAQTRltSTEEF 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 240 KNITV-----APQVKLQDIAQIEL-KQNYDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQFSIKLL 313
Cdd:PRK15127 247 GKILLkvnqdGSRVRLRDVAKIELgGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 314 ASTHEQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRLV 393
Cdd:PRK15127 327 YDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 394 DDSIVVIENIFRRLQKEPF-SKDIIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILSSLIVAL 472
Cdd:PRK15127 407 DDAIVVVENVERVMAEEGLpPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVAL 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 473 TVVPLMAFLLLK---KTKHRKPS-------------SSPRYVATLKWALSHKFIILLTSFLLFAGSIAAYILLPKSNIKS 536
Cdd:PRK15127 487 ILTPALCATMLKpiaKGDHGEGKkgffgwfnrmfekSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 537 EDDTMLSVNMTFPADYNSEsQKQKAFDfekkllsnpDVTDVILrmgssaedaqwgQTTKNNLASIFVV-----FKKGSNI 611
Cdd:PRK15127 567 EDQGVFLTMVQLPAGATQE-RTQKVLN---------EVTDYYL------------TKEKNNVESVFAVngfgfAGRGQNT 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 612 DQYIKDLKK-DHKSFEPAELDYIK----TSYSSSGGGNNLQFNVTATNET--------NLKKAANIVETKL--------- 669
Cdd:PRK15127 625 GIAFVSLKDwADRPGEENKVEAITmratRAFSQIKDAMVFAFNLPAIVELgtatgfdfELIDQAGLGHEKLtqarnqllg 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 670 ---KSMDALSKVKTN-LEDSkKEWQIHIDQTKAEQLGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMIEHKKENINKQ 745
Cdd:PRK15127 705 eaaKHPDMLVGVRPNgLEDT-PQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLP 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 746 TDILNANILSPINGPIPLKDIATISEKQLQTEIFHKDGKETIQITAEASSedlSKVSAEVNNAITNL--DLPSGAKVNIA 823
Cdd:PRK15127 784 DDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAP---GKSTGEAMELMEELasKLPTGVGYDWT 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 824 GAteSMQENFT--DLFKIMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIV 901
Cdd:PRK15127 861 GM--SYQERLSgnQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLS 938
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1258771808 902 VTNAIVLIERVQQNREN-GMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFgQSQAGSMVSKSLAVVVIGGL 974
Cdd:PRK15127 939 AKNAILIVEFAKDLMDKeGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVI-SSGAGSGAQNAVGTGVMGGM 1011
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
17-974 |
5.26e-55 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 207.78 E-value: 5.26e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 17 IMVFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDGIISSTHEGLSRIDIAY 96
Cdd:PRK09577 14 VISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLSLTF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 97 TSKANMKDAAREVEKAINTI--KLPKDVTKpvvsqlNTSMIPLAQITIQKQNGFSKADEKQIEKE--------IVPQLES 166
Cdd:PRK09577 94 KQGVNADLAAVEVQNRLKTVeaRLPEPVRR------DGIQVEKAADNIQLIVSLTSDDGRLTGVElgeyasanVLQALRR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 167 IDGVANVMFFGKSTSeLSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKEEYNLRVIGEV------KNINEIK 240
Cdd:PRK09577 168 VEGVGKVQFWGAEYA-MRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVfadaplKTPEDFG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 241 NITVAPQ-----VKLQDIAQIELKQN-YDTISHINGEEGTGLIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQFSIKLLA 314
Cdd:PRK09577 247 AIALRARadgsaLYLRDVARIEFGGNdYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPGVKYQIPY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 315 STHEQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRLVD 394
Cdd:PRK09577 327 ETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIGILVD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 395 DSIVVIENIFRRLQKEPFSK-DIIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSILSSLIVALT 473
Cdd:PRK09577 407 DAIVVVENVERLMVEEGLSPyDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGFSAFLALS 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 474 VVPLMAFLLLKKT---KHRK-----------PSSSPRYVATLKWALSHKFIILLTSFLLFAGSIAAYILLPKSNIKSEDD 539
Cdd:PRK09577 487 LTPALCATLLKPVdgdHHEKrgffgwfnrfvARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPTAFLPDEDQ 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 540 TMLSVNMTFPADYNSESQKQKAFDFEKKLLSNPDVTDVILRMGSSAedaqWGQTTknNLASIFVVFKKGS---NIDQYIK 616
Cdd:PRK09577 567 GNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNL----YGEGP--NGGMIFVTLKDWKerkAARDHVQ 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 617 ---DLKKDHKSFEPAELDYIKTSYSSSGGGNNLQFNVTATNETNLKKAA-NIVETKLKSMDALSKVKTNL----EDSKKE 688
Cdd:PRK09577 641 aivARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAfVAAREQLLAEGAKDPALTDLmfagTQDAPQ 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 689 WQIHIDQTKAEQLGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMIEHKKENINKQTDILNANILSPINGPIPLKDIAT 768
Cdd:PRK09577 721 LKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVPLAAFAT 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 769 ISEKQLQTEIFHKDGKETIQITAEASSedlSKVSAEVNNAITNL--DLPSGAKVNIAGatESMQENFTD-----LFkimG 841
Cdd:PRK09577 801 LHWTLGPPQLTRYNGYPSFTINGSAAP---GHSSGEAMAAIERIaaTLPAGIGYAWSG--QSFEERLSGaqapmLF---A 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 842 IAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIERVQQNRENGME 921
Cdd:PRK09577 873 LSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQRMS 952
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|...
gi 1258771808 922 TRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGqSQAGSMVSKSLAVVVIGGL 974
Cdd:PRK09577 953 LADAALEAARLRLRPIVMTSLAFGVGVLPLAFA-SGAASGAQIAIGTGVLGGV 1004
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
276-953 |
6.97e-26 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 114.57 E-value: 6.97e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 276 LIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQ-FSIKL---LASTHEQVENAVTSMGKEVILGAIAATLIILIFLRNFRT 351
Cdd:COG1033 165 VVTLDPDPLSSDLDRKEVVAEIRAIIAKYEDPgVEVYLtgfPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRG 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 352 TLIAVVSIPLSILLTLFLLHQSNITLNILT--LGGLAVAVGrlVDDSIVVIENIFRRLQKEPFSKDIIIDATKEVAVAIT 429
Cdd:COG1033 245 VLLPLLVVLLAVIWTLGLMGLLGIPLSPLTilVPPLLLAIG--IDYGIHLLNRYREERRKGLDKREALREALRKLGPPVL 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 430 SSTLTTVAVFLPIGLVSgvigklmLPMV--LAVVYSI--LSSLIVALTVVP-LMAFLLLKKTKHRKPSSSPRYVATL--- 501
Cdd:COG1033 323 LTSLTTAIGFLSLLFSD-------IPPIrdFGIVAAIgvLLAFLTSLTLLPaLLSLLPRPKPKTRRLKKPPELGRLLakl 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 502 -KWALSHKFIILLTSFLLFAGSIAAYillpkSNIKSEDDtmlsvnmtFPADYNSESQKQKAFDFEKKLLSNPDVTDVILr 580
Cdd:COG1033 396 aRFVLRRPKVILVVALVLAVVSLYGI-----SRLKVEYD--------FEDYLPEDSPIRQDLDFIEENFGGSDPLEVVV- 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 581 mgssaedaqwgqttknnlasifvvfkkgsnidqyikDLKKDHKSFEPAELDYIKtsysssgggnnlQFNVTATNETNLKK 660
Cdd:COG1033 462 ------------------------------------DTGEPDGLKDPEVLKEID------------RLQDYLESLPEVGK 493
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 661 AANIVetklksmDALSKVKTNLEDSKKEWqihidqtkaEQLGLTPELAAQqVAFLMKKSPIGEIS--INNEKTTIMIehk 738
Cdd:COG1033 494 VLSLA-------DLVKELNQALNEGDPKY---------YALPESRELLAQ-LLLLLSSPPGDDLSrfVDEDYSAARV--- 553
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 739 keninkqtdilnanilspingpiplkdiatisekqlqteifhkdgkeTIQItAEASSEDLSKVSAEVNNAITNLDLPSGA 818
Cdd:COG1033 554 -----------------------------------------------TVRL-KDLDSEEIKALVEEVRAFLAENFPPDGV 585
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 819 KVNIAG----ATESMQENFTDLFKIMGIAIGIVYLIMVITFGQARAPFAILFS--LPLAAVGGILGLIisRTPVDINSLI 892
Cdd:COG1033 586 EVTLTGsavlFAAINESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLIPnlLPILLTFGLMGLL--GIPLNIATAV 663
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1258771808 893 GALMLIGIVVTNAIVLIERVQQNRENGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLF 953
Cdd:COG1033 664 VASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLF 724
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
786-971 |
4.92e-14 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 76.44 E-value: 4.92e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 786 TIQITAEASSEDLSKVSAEVNNAITNLDLPsGAKVNIAG----ATESMQENFTDLFKIMGIAIGIVYLIMVITFGQARAP 861
Cdd:COG1033 167 TLDPDPLSSDLDRKEVVAEIRAIIAKYEDP-GVEVYLTGfpvlRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGV 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 862 FAILFSLPLAAVG--GILGLIIsrTPVDINSLIGALMLIGIVVTNAIVLIERVQQNRENGMETRDALLEAGSTRLRPIIM 939
Cdd:COG1033 246 LLPLLVVLLAVIWtlGLMGLLG--IPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLL 323
|
170 180 190
....*....|....*....|....*....|....*.
gi 1258771808 940 TAVTTIVAMLPLLFGQSQA----GSMVSKSLAVVVI 971
Cdd:COG1033 324 TSLTTAIGFLSLLFSDIPPirdfGIVAAIGVLLAFL 359
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
509-982 |
1.13e-13 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 75.79 E-value: 1.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 509 FIILLTSFLLFAGSIAaYILLPKSNIKSEDDTMLSVNMTFPAdYNSESQKQKafdfekkllsnpdVTDVILR-MGSSAED 587
Cdd:pfam00873 11 FTLVLAIAILLAGILS-FFSLPVDAFPEIAPPTVQVSTSYPG-ASPEEVEDT-------------VTQPIEQaMNGLDGL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 588 AQWGQTTKNNLASIFVVFKKGSNIDQYIKDLKKDHKSFE---PAELDYIKTSYSSSGGGNNLQFNVTATN-ETNLKKAAN 663
Cdd:pfam00873 76 KYMSSQSSYGLSSITLTFELGTDIDIARQDVQNRLQLATpllPEGVQRPGISVIKTSLGPIMVLAVTSPDgSYTQTDLRD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 664 IVETKLKsmDALSKVK-----TNLEDSKKEWQIHIDQTKAEQLGLTPELAAQQVAFLMKKSPIGEISINNEKTTIMIEHK 738
Cdd:pfam00873 156 YADTNIK--PQLSRVPgvgdvQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 739 KENINkqtDILNANILSPINGPIPLKDIATI-SEKQLQTEIFHKDGKE----TIQITAEASSEDLSK-VSAEVNNAITNL 812
Cdd:pfam00873 234 LQSAE---DFEKIIVKNQDGSPVRLRDVATVeLGSELYRGFATFNGKPavglGVQKLPGANAIETADaVRAKLAELKPTF 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 813 dlPSGAKVNIA-GATESMQENFTDLFKIMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSL 891
Cdd:pfam00873 311 --PQGVEIVVVyDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTL 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 892 IGALMLIGIVVTNAIVLIERVQQN-RENGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGQSQAGSMVsKSLAVVV 970
Cdd:pfam00873 389 GGLVLAIGLVVDDAIVVVENIERVlEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIF-RQFAITI 467
|
490
....*....|..
gi 1258771808 971 IGGLAVSTVLTL 982
Cdd:pfam00873 468 VLAILLSVLVAL 479
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
751-975 |
2.04e-13 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 74.42 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 751 ANILSPINGPIPlkdiATISEkqlqteifhkDGKET-IQITAEASSEDLSKVSAE-VNNAITNLDlPSGAKVNIAGA--- 825
Cdd:COG2409 95 AGVQDPWDDPAA----GLVSE----------DGKAAlVTVTLDGDAGDEAAEAVDaLRDAVAAAP-APGLTVYVTGPaal 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 826 TESMQENF-TDLFKIMGIAIGIVYLIMVITFGQARAPFailfsLPLAAVG-------GILGLIISRTPVDINSLIGALML 897
Cdd:COG2409 160 AADLNEAFeEDLGRAELITLPVALVVLLLVFRSLVAAL-----LPLLTAGlavgvalGLLALLAAFTDVSSFAPNLLTML 234
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1258771808 898 -IGIVVTNAIVLIERVQQNRENGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFgqsqAGSMVSKSLAVVVIGGLA 975
Cdd:COG2409 235 gLGVGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLL----AGLPFLRSMGPAAAIGVA 309
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
282-490 |
2.63e-09 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 61.41 E-value: 2.63e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 282 PSKNAVAIGKEIDKKIKDISKQYKDQFSI----KLLASTHEQVENAVTSMgkeVILGAIAATLIILIFLRNFRTTLIAVV 357
Cdd:COG1033 561 DSEEIKALVEEVRAFLAENFPPDGVEVTLtgsaVLFAAINESVIESQIRS---LLLALLLIFLLLLLAFRSLRLGLISLI 637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 358 SIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRLVDDSIVVIENIFRRLQKEPFSKDIIIDATKEVAVAITSSTLTTVA 437
Cdd:COG1033 638 PNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAA 717
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1258771808 438 VFLpIGLVSGvigklmLPMV----LAVVYSILSSLIVALTVVPLMAfLLLKKTKHRK 490
Cdd:COG1033 718 GFG-VLLFSS------FPPLadfgLLLALGLLVALLAALLLLPALL-LLLDPRIAKK 766
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
3-491 |
2.71e-09 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 61.20 E-value: 2.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 3 RLTKFSLKNRAAIIIMVFLISILGVYSSSKLPMEFLPSID--NPAITVTTL-SQGLDAetmTKDVTDPLEKQFRNLEHID 79
Cdd:COG3696 520 PLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDegDLLVMATLPpGISLEE---SVELGQQVERILKSFPEVE 596
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 80 GIIS-------STH-EGLSRIDI--------AYTSKANMKDAAREVEKAINTIK-LPKDVTKPVvsQLNTSMIpL----A 138
Cdd:COG3696 597 SVVSrtgraedATDpMGVNMSETfvilkprsEWRSGRTKEELIAEMREALEQIPgVNFNFSQPI--QMRVDEL-LsgvrA 673
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 139 QITIqKQNGfskADEKQIEK---EIVPQLESIDGVANVMFFgKST--SELSIVLDPNKLKDKNVTSEQVLKVVQ----GK 209
Cdd:COG3696 674 DVAV-KIFG---DDLDVLRRlaeQIEAVLKTVPGAADVQVE-RVTglPQLDIRIDRDAAARYGLNVADVQDVVEtaigGK 748
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 210 ETSTptgaiTVNKEE-YNLRVIGE---VKNINEIKNITV-AP---QVKLQDIAQIELKQNYDTISHINGeegtgliimke 281
Cdd:COG3696 749 AVGQ-----VYEGERrFDIVVRLPeelRDDPEAIRNLPIpTPsgaQVPLSQVADIEVVEGPNQISRENG----------- 812
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 282 psKNAVAIG------------KEIDKKIKDiskqykdqfSIKLLASTH-E---QVENAVTSMGKEVILGAIAATLI-ILI 344
Cdd:COG3696 813 --RRRIVVQanvrgrdlgsfvAEAQAKVAE---------QVKLPPGYYiEwggQFENLQRATARLAIVVPLALLLIfLLL 881
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 345 FL--RNFRTTLIAVVSIPLSILLTLFLLHQSNITLNI------LTLGGLAVavgrlvDDSIVVIENiFRRLQKEPFS-KD 415
Cdd:COG3696 882 YLafGSVRDALLILLNVPFALIGGVLALWLRGMPLSVsagvgfIALFGVAV------LNGVVLVSY-INQLRAEGLDlRE 954
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1258771808 416 IIIDATKE--VAVAITSstLTTVAVFLPIgLVSGVIGK-LMLPMVLAVVYSILSSLIVALTVVPLMAFLLLKKTKHRKP 491
Cdd:COG3696 955 AIIEGALErlRPVLMTA--LVAALGLLPM-ALSTGPGSeVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAA 1030
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
787-971 |
3.09e-09 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 61.01 E-value: 3.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 787 IQITAEASSEDLSKVSAEVNNAITNLDLPSGAKVNIAGA------TESMQENftDLFKIMGIAIGIVYLIMVITFGQARA 860
Cdd:TIGR00921 142 VQLKSDADYKQVVPIYNDVERSLERTNPPSGKFLDVTGSpainydIEREFGK--DMGTTMAISGILVVLVLLLDFKRWWR 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 861 PF----AILFSLplAAVGGILGLIisRTPVDINSLIGALMLIGIVVTNAIVLIERVQQNRENGMETRDALLEAGSTRLRP 936
Cdd:TIGR00921 220 PLlplvIILFGV--AWVLGIMGWL--GIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRA 295
|
170 180 190
....*....|....*....|....*....|....*
gi 1258771808 937 IIMTAVTTIVAMLPLLFGQSQAGSMVSKSLAVVVI 971
Cdd:TIGR00921 296 VLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLI 330
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
781-970 |
5.04e-09 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 59.23 E-value: 5.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 781 KDGKETI-QITAE---ASSEDLSKVSAeVNNAITNLDLPSGAKVNIAG---ATESMQENFT-DLFKIMGIAIGIVYLIMV 852
Cdd:pfam03176 82 PDGKAAYvVVTLEgdpGTTEADESVAA-VRDAVEQAPPPEGLKAYLTGpaaTVADLRDAGDrDLGLIEAVTLVVIFIILL 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 853 ITFGQARAPFailfsLPLAAVGgiLGLIISRTPVDINSLIGAL------------MLIGIVVTNAIVLIERVQQNRENGM 920
Cdd:pfam03176 161 IVYRSVVAAL-----LPLLTVG--LSLGAAQGLVAILAHILGIglstfalnllvvLLIAVGTDYALFLVSRYREELRAGE 233
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1258771808 921 ETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGQ----SQAGSMVSKSLAVVV 970
Cdd:pfam03176 234 DREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARlpvfAQVGPTIAIGVLVDV 287
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
799-959 |
1.16e-07 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 56.16 E-value: 1.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 799 SKVSAEVNNAITNLDLP--SGAKVNIAGATESMQENFTDLFKIMGIA----IGIVYLIMVITFGQARAPFAILFSLplaa 872
Cdd:TIGR03480 228 EKAINAIRAAAKDLRLDedHGVTVRLTGEVALSDEELATVSEGATVAgllsFVLVLVLLWLALRSPRLVFAVLVTL---- 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 873 vggILGLIISR-------TPVDINSLIGALMLIGIVVTNAIVLIERVQQNRENGMETRDALLEAGSTRLRPIIMTAVTTI 945
Cdd:TIGR03480 304 ---IVGLILTAafatlavGHLNLISVAFAVLFIGLGVDFAIQFSLRYREERFRGGNHREALSVAARRMGAALLLAALATA 380
|
170
....*....|....*...
gi 1258771808 946 VAMLPLLF----GQSQAG 959
Cdd:TIGR03480 381 AGFFAFLPtdykGVSELG 398
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-484 |
1.05e-06 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 53.07 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 3 RLTKFSLKNRAAIIIMVFLISILGVYSSSKLPMEFLPSIDNPAITVTT-LSQGLDAETMT---KDVTDPLeKQFRNLEHI 78
Cdd:pfam00873 518 KLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVTSAqLPPGVSLDQTQrvmKQVEKIL-KEKPEVESV 596
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 79 DGI----ISSTHEGLSRIDIAYTSK--------ANMKDA-AREVEKAINTIKLPKDVTKPVVSQLNTSMIPLAQITIQKQ 145
Cdd:pfam00873 597 FAVtgfaFSGDNNGPNSGDAFISLKpwkerpgpEKSVQAlIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVK 676
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 146 NGFSKADE-KQIEKEIVPQLESIDGVANVMFFGKS-TSELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKE 223
Cdd:pfam00873 677 IFGDDLDAlDEARNQILAALAQLPGLSDVRSDGQEdQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGR 756
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 224 EYNLRVIGEVKNINEIKNITVAP-------QVKLQDIAQIELKQNYDTISHINGeegtglIIMKEPSKNAVA--IGKEID 294
Cdd:pfam00873 757 VYDVVVQLPEDFRSSPEDIGQLYvrnpygkMIPLSAFAKIEWGYGPPSINRYNG------FRSIVISGNVAAgdSLGDAM 830
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 295 KKIKDISKQYKDQFSIKLLASTheQVENAVTSMGKEVILGAIAATLI--ILIFL-RNFRTTLIAVVSIPLSILLTLFLLH 371
Cdd:pfam00873 831 EAMAQIAKQVKLPPGYGYTWTG--QFEQEQLAGNSLPILIALALLVVflVLAALyESWSDPLSIMLTVPLALVGALLALW 908
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 372 QSNITLNILTLGGLAVAVGRLVDDSIVVIENIFRRLQKEPFS-KDIIIDATKEVAVAITSSTLTTVAVFLPIGLVSGVIG 450
Cdd:pfam00873 909 LRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKSlEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGS 988
|
490 500 510
....*....|....*....|....*....|....
gi 1258771808 451 KLMLPMVLAVVYSILSSLIVALTVVPLMaFLLLK 484
Cdd:pfam00873 989 ELQQPLGIVVFGGLVTSTVLTLLVVPVF-YVLFH 1021
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
318-483 |
7.53e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 49.84 E-value: 7.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 318 EQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNILTLGGLAVAVGRLVDDSI 397
Cdd:TIGR00921 560 EMHELVNEGMRRMTIAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSI 639
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 398 VVIENIFRRLqKEPFSKDIIIDATKEVAVAITSSTLTTVAVFLpiGLVSGVIGkLMLPMVLAVVYSILSSLIVALTVVPl 477
Cdd:TIGR00921 640 HLAERYFEER-KEHGPKEAITHTMERTGPGILFSGLTTAGGFL--SLLLSHFP-IMRNFGLVQGIGVLSSLTAALVVFP- 714
|
....*.
gi 1258771808 478 mAFLLL 483
Cdd:TIGR00921 715 -ALLVL 719
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
333-975 |
1.21e-05 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 49.23 E-value: 1.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 333 LGAIAATLIILIF-LRNFRttLIAVVSIplsilltlfllhqsniTLN---ILTLGGLAVAVGRL---------------V 393
Cdd:TIGR03480 276 LLSFVLVLVLLWLaLRSPR--LVFAVLV----------------TLIvglILTAAFATLAVGHLnlisvafavlfiglgV 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 394 DDSIVVIENIFRRLQKEPFSKDIIIDATKEVAVAITSSTLTTVA---VFLP--------IGLVSGVigklmlpmvlavvy 462
Cdd:TIGR03480 338 DFAIQFSLRYREERFRGGNHREALSVAARRMGAALLLAALATAAgffAFLPtdykgvseLGIIAGT-------------- 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 463 SILSSLIVALTVVPlmAFL-LLKKTKHRKPSSSPRYVATLKWALSHKFIIlLTSFLLFAgsIAAYILLPKSNIkseddtm 541
Cdd:TIGR03480 404 GMFIALFVTLTVLP--ALLrLLRPPRRRKPPGYATLAPLDAFLRRHRRPV-LGVTLILG--IAALALLPQLRF------- 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 542 lsvnmtfpaDYNS---ESQKQKAFDFEKKLLSNPDVTdvILRMGSSAEDAQWGQTTKNNLASIFVVFKKGSnIDQYIKDl 618
Cdd:TIGR03480 472 ---------DFNPlnlQDPKTESVRTFLELLADPDTS--PYSAEVLAPSAPEARALTERLEALPEVDQVVT-LPDFVPD- 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 619 KKDHKSFEPAELDYIKTSYSSSggGNNLQFNVTATNETNLKKAANIVETKL-KSMDALSKVKTNLedskkewqihidqtk 697
Cdd:TIGR03480 539 DQEAKLALIADLALVLGPTLNP--GEADPAPSAEEVAAALRRLAARLRAAAaKSQDPDAAAAGRL--------------- 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 698 AEQLGLTPELAAQQVAFLMKKSpigeisinnektTIMIEHKKENINKQTDILNANilspingPIPLKDIAtiseKQLQTE 777
Cdd:TIGR03480 602 AASLDRLLAKAPAQAATLRALQ------------GALLAGLPGELDRLRDSLQAE-------PVTLEDLP----PDLRRR 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 778 IFHKDGKETIQITAEASSEDLSKVsAEVNNAITNLDlP--SGAKVNIAGATESMQENFTDLFKIMGIAIGIvylIMVITF 855
Cdd:TIGR03480 659 WVAKDGRARLEVFPKEDLNDNEAL-RRFVRAVRKVA-PdaTGAPVSILESGDTVVGAFLQAFIYALVAITV---LLLLTL 733
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 856 GQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLIGIVVTNAIVLIERVQQNRENGmetrdALLeAGSTRlR 935
Cdd:TIGR03480 734 RRVRDVLLVLAPLLLAGLLTVAAMVLLGIPFNFANIIALPLLLGLGVDFGIYMVHRWRNGVDSG-----NLL-QSSTA-R 806
|
650 660 670 680
....*....|....*....|....*....|....*....|....
gi 1258771808 936 PIIMTAVTTIVAMLPLLF----GQSQAGSMVSKSLAVVVIGGLA 975
Cdd:TIGR03480 807 AVFFSALTTATAFGSLAVsshpGTASMGILLSLGLGLTLLCTLI 850
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
8-495 |
2.02e-05 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 48.60 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 8 SLKNRAAIIIMVFLISILGVYSSSKLPMEFLPSIDNPAITVTTLSQGLDAETMTKDVTDPLEKQFRNLEHIDGIISSTHE 87
Cdd:TIGR00914 533 VLAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGT 612
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 88 GLSRIDIA----------------YTSKANMKDA--AREVEKAINTIKLPKDVTKPVVSQLNTSMIPLAQITIQKQNGFS 149
Cdd:TIGR00914 613 AEIATDPMppnasdtyiilkpesqWPEGKKTKEDliEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDD 692
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 150 KADEKQIEKEIVPQLESIDGVANVMFfgKSTS---ELSIVLDPNKLKDKNVTSEQVLKVVQGKETSTPTGAITVNKEEY- 225
Cdd:TIGR00914 693 LDDLDATAEKISAVLKGVPGAADVKV--EQTTglpYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFd 770
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 226 -NLRVIGEVK-NINEIKNITV-APQVKLQDIAQIELKQnydtISHINGEEGTGLIiMKEPSKNAVAI-----GKEIDKKI 297
Cdd:TIGR00914 771 iVIRLPESLReSPQALRQLPIpLPLSEDARKQFIPLSD----VADLRVSPGPNQI-SRENGKRRVVVsanvrGRDLGSFV 845
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 298 KDISKQYKDQfsIKLLASTH-------EQVENAVTSMGKEVILGAIAATLIILIFLRNFRTTLIAVVSIPLSILLTLFLL 370
Cdd:TIGR00914 846 DDAKKAIAEQ--VKLPPGYWitwggqfEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFAL 923
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 371 HQSNITLNILTLGGLAVAVGRLVDDSIVVIENIFRRLQKEPFSKDiiidATKEVAVAITSSTLTTVAV----FLPIGLVS 446
Cdd:TIGR00914 924 WLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDE----AVYEGALTRVRPVLMTALVaslgFVPMAIAT 999
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1258771808 447 GVIGKLMLPMVLAVVYSILSSLIVALTVVPLMAFLLLKKTKHRKPSSSP 495
Cdd:TIGR00914 1000 GTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHRRRHKGRKEHEP 1048
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
242-500 |
3.29e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 44.84 E-value: 3.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 242 ITVAPQVKLQDI-AQIELKQNYDTISHINGEEGTGLII-MKEPSKNAVAIGKEIDKKIKDISKqykdqfsiKLLASTHEQ 319
Cdd:PRK13024 492 IRTDQPVDLEQVrADLKELGLGEVNIVTFGSDNNQVLVrTYGILSDDEEADTEIVAKLKNALK--------NDKGGTIPS 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 320 VENAVTSMGKEVILGAIAATLI------ILIFLR-NFRTTLIAVVSIplsilltlflLHQSNITLNILTLGGL-----AV 387
Cdd:PRK13024 564 SETVGPTVGKELARNAIIAVLIaligilLYILIRfEWTFSLGAILAL----------LHDVLIVIGFFSLFRLevdltFI 633
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 388 A-----VGRLVDDSIVV---IENIFRRLQKEPFsKDIIIDATKEVAVAITSSTLTTVAVFLPIGLVSG-VIGKLMLPMVL 458
Cdd:PRK13024 634 AailtiIGYSINDTVVVfdrIRENLRLYKKKDL-REIVNKSINQTLSRTINTSLTTLLVLLALLIFGGsSLRNFSLALLV 712
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1258771808 459 AVVYSILSSLIVAltvVPLMAFLLLKKTKHRKPSSSPRYVAT 500
Cdd:PRK13024 713 GLIVGTYSSIFIA---APLWLDLEKRRLKKKKKRKKVKKWEV 751
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
747-982 |
3.76e-04 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 44.63 E-value: 3.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 747 DIlnANI-LSPING-PIPLKDIATISE-KQLQTEIFHKDGK-ETIQITAEA-SSEDLSKVSAEVNNAITNLD--LPSGAK 819
Cdd:COG3696 242 DI--ENIvVKTRNGtPVLLRDVAEVRIgPAPRRGAATLNGEgEVVGGIVLMlKGENALEVIEAVKAKLAELKpsLPEGVK 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 820 VN--------IAGATESMQENftdlfkiMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSL 891
Cdd:COG3696 320 IVpfydrsdlIDRAIHTVTKN-------LLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 892 IGALMLIGIVVTNAIVLIE----RVQQNRE--NGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFGQSQAGSMVSkS 965
Cdd:COG3696 393 GGLAIDFGIIVDGAVVMVEnilrRLEENRAagTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFR-P 471
|
250
....*....|....*..
gi 1258771808 966 LAVVVIGGLAVSTVLTL 982
Cdd:COG3696 472 MALTVIFALLGALLLSL 488
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
835-958 |
1.24e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 42.92 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 835 DLFKIMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSL-IGAlMLIGIVVTNAI-VLIERv 912
Cdd:COG4258 250 DISTIGLISLLGILLLLLLVFRSLRPLLLGLLPVAVGALAGLAAVSLVFGSVHGITLgFGS-SLIGVAVDYSLhYLTHR- 327
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1258771808 913 qqnRENGMETRDALLEagstRLRP-IIMTAVTTIVAMLPLLFGQSQA 958
Cdd:COG4258 328 ---RAAGEWDPRAALR----RIWPtLLLGLLTTVLGYLALLFSPFPG 367
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
786-953 |
1.82e-03 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 42.06 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 786 TIQITAEASSEDLSKVSAEVNNAItnLDLPSGAKVNIAGAT----ESMQENFTDLFKIMGIAIGIVYLIMVITFGQARAP 861
Cdd:COG2409 467 QVVPDGDPDSPEAIDLVDRLRDAA--APALEGAEVLVGGTTavniDISDALADDLPLVIPVVLGLIFLLLLLLFRSVVAP 544
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 862 F-AI---LFSLpLAAVG----------GILGLiisrTPVDINSLIgALMLIGIVVtnA------IVLIERVQQNRENGME 921
Cdd:COG2409 545 LkAVltnLLSL-GAALGvlvlvfqhgwLLLGF----TPGPLDSFV-PLLLFVILF--GlgmdyeVFLVSRIREEYDRGGG 616
|
170 180 190
....*....|....*....|....*....|....*...
gi 1258771808 922 TRDALLEA-GSTRlRPI-----IMTAVTTIVAMLPLLF 953
Cdd:COG2409 617 TREAVIRGlARTG-RVItsaalIMAAVFAAFATSPLVF 653
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
839-953 |
3.95e-03 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 39.55 E-value: 3.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 839 IMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGlIISRTPVDIN--SLIGALMLIGIVVTNAIVLIERVQQN- 915
Cdd:TIGR00916 50 IIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVILILG-VLSLFGATLTlpGIAGLLTIIGYSVDDTVVIFDRIREEl 128
|
90 100 110
....*....|....*....|....*....|....*....
gi 1258771808 916 -RENGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLF 953
Cdd:TIGR00916 129 rKYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYV 167
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
842-975 |
5.23e-03 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 39.13 E-value: 5.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 842 IAIGIVYLIMVITFG---QARAPFAILFSLP---LAAVGGilgLIISRTPVDINSLIGALMLIGIVVTNAIVLIERVQQN 915
Cdd:pfam02355 35 LALLFALLLILIYVGlrfEWRFALGAIIALAhdvIITVGV---FSLFGIEVDLATVAALLTIIGYSVNDTVVVFDRVREN 111
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1258771808 916 --RENGMETRDALLEAGSTRLRPIIMTAVTTIVAMLPLLFgqsqAGSMVSKSLAVVVIGGLA 975
Cdd:pfam02355 112 lrKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFV----FGGGSLKDFSLALLVGVI 169
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
820-975 |
6.85e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 40.22 E-value: 6.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1258771808 820 VNIAGATESMQENF-TDLFKIMGIAIGIVYLIMVITFGQARAPFAILFSLPLAAVGGILGLIISRTPVDINSLIGALMLI 898
Cdd:COG4258 624 VDRKAESSSLFGRYrNDALWLLLLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVL 703
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1258771808 899 GIVVTNAIVLIERVQQNREngmetrdalleaGSTRLRPIIMTAVTTIVAMLPLLFGQSQAgsmvSKSLAVVVIGGLA 975
Cdd:COG4258 704 GIGIDYALFFTEGLLDKGE------------LARTLLSILLAALTTLLGFGLLAFSSTPA----LRSFGLTVLLGIL 764
|
|
| |
