|
Name |
Accession |
Description |
Interval |
E-value |
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
2-398 |
6.63e-131 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 382.29 E-value: 6.63e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 2 LVYHLFWNQKGKRSPKLNSAIFIVLCCLATVLCITFAAKTNNGFQFDMRHIVLIVGTLTGGPIAGGSILVVLNIYRLLLG 81
Cdd:COG5806 16 FIYQIFWEDRRRNKPVKNRMLIGVLSSIAIILCMTFPIHITDGFIFDLRQVPIILGTLYGGWRVGLFLFLILLLYRFYLG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 82 GIGVFPSLIGSVLLFIVLLLTYKFFNRTSNRIKITLAII----YSLTYG-FSWIPFFLSKVTnktdyIPHIIVYELCSML 156
Cdd:COG5806 96 GEGVFVTLLVYTVILILPLLLRRKFHRLSRKGKIVLAILlsflSALLLLlLAIIFIADISEL-----LDFILYFIIIQLL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 157 GTILILYLLHILQTQVRLQNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIDIAINGIEQA 236
Cdd:COG5806 171 AMLIAVYLIENLIENILLRKELQRAEKLEVVSELAASIAHEVRNPLTVVRGFIQLLQEPELSDEKRKQYIRIALEELDRA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 237 NHVLTDYLTFAKPSIEKEQTLQLEEELLHALSLITPLANLTNVrthYIKQST--SFFIAGEKQKLNQCLLNILKNCIEAM 314
Cdd:COG5806 251 EAIITDYLTFAKPQPEKLEKIDVSEELEHVIDVLSPYANMNNV---EIQTELepGLYIEGDRQKLQQCLINIIKNGIEAM 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 315 PKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLL 394
Cdd:COG5806 328 PNGGTLTIDVSIDKNKVIISIKDTGVGMTKEQLERLGEPYFSTKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTI 407
|
....
gi 1259951092 395 TFPL 398
Cdd:COG5806 408 TLPL 411
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
171-401 |
1.84e-70 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 229.48 E-value: 1.84e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 171 QVRLQNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQerKLYIDIAINGIEQANHVLTDYLTFAKPS 250
Cdd:COG5809 254 RKKLEELLRKSEKLSVVGELAAGIAHEIRNPLTSLKGFIQLLKDTIDEEQ--KTYLDIMLSELDRIESIISEFLVLAKPQ 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 251 IEKEQTLQLEEELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYF-TLVPDHK 329
Cdd:COG5809 332 AIKYEPKDLNTLIEEVIPLLQPQALLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNITIeTKAEDDD 411
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1259951092 330 HIQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPLIQK 401
Cdd:COG5809 412 KVVISVTDEGCGIPEERLKKLGEPFYTTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPIKLS 483
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
177-398 |
4.13e-65 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 215.75 E-value: 4.13e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 177 ELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSdtcTEQERKLYIDIAINGIEQANHVLTDYLTFAKPSIEKEQT 256
Cdd:COG5805 277 LMARSEKLSIAGQLAAGIAHEIRNPLTSIKGFLQLLQP---GIEDKEEYFDIMLSELDRIESIISEFLALAKPQAVNKEK 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 257 LQLEEELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIK 336
Cdd:COG5805 354 ENINELIQDVVTLLETEAILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVI 433
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1259951092 337 DTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:COG5805 434 DEGIGIPEERLKKLGEPFFTTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPL 495
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
171-399 |
3.74e-61 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 201.55 E-value: 3.74e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 171 QVRLQNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSDTcTEQERKLYIDIAINGIEQANHVLTDYLTFAKPS 250
Cdd:COG5807 131 RKEAEDKLLRSEKLSVAGELAAGIAHEIRNPLTSIKGFLQLLQESR-EDSEREEYFNIIISEIDRINTIITELLVLSKPK 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 251 IEKEQTLQLEEELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKH 330
Cdd:COG5807 210 KFNFKKLNLNDVLEDVIALLSTEAILKNISIKYDLADDEPVINGDKNQLKQVFINLIKNAIEAMETGGNITIKTYVEGDF 289
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1259951092 331 IQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPLI 399
Cdd:COG5807 290 VVISVKDEGIGIPEEVLEKIGEPFFTTKEEGTGLGLSICKKIIEEHNGTIEVESKPGKGTTFTIYLPLY 358
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
171-402 |
1.11e-60 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 200.46 E-value: 1.11e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 171 QVRLQNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSDtCTEQERKLYIDIAINGIEQANHVLTDYLTFAKPS 250
Cdd:COG3852 119 RKRLERELRRAEKLAAVGELAAGLAHEIRNPLTGIRGAAQLLERE-LPDDELREYTQLIIEEADRLNNLVDRLLSFSRPR 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 251 IEKEQTLQLEEELLHALSLITPLANlTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTL------ 324
Cdd:COG3852 198 PPEREPVNLHEVLERVLELLRAEAP-KNIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTrverqv 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 325 ----VPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPLIQ 400
Cdd:COG3852 277 tlggLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPLEQ 356
|
..
gi 1259951092 401 KT 402
Cdd:COG3852 357 AE 358
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
144-400 |
9.00e-56 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 189.96 E-value: 9.00e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 144 IPHIIVYELCSMLGTILILYLLHILQTQVRLQNElINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQsDTCTEQERK 223
Cdd:COG5808 199 IRKLIILVLISIIFLLLQYNLLKRKTLLERVIQE-INTQKLELIGTFAASTAHEIRNPLTSIKGFIQLLQ-EKYPELEDQ 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 224 LYIDIAINGIEQANHVLTDYLTFAKPSIEKEQTLQLEEELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCL 303
Cdd:COG5808 277 KYFDIIQEEIQRINQIVSEFLVLGKPTAKKLELDDLNELIEEILSIIDSEANLKNIRVEKQSLDEPLHIKCDKDRIKQVL 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 304 LNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDII 383
Cdd:COG5808 357 LNLIKNAIEAMKEGGKLTISIENDDEKAVIEVIDNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIE 436
|
250
....*....|....*..
gi 1259951092 384 SEKGIGTTFLLTFPLIQ 400
Cdd:COG5808 437 SEEGKGTTFTIRLPLKK 453
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
177-402 |
1.35e-52 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 180.93 E-value: 1.35e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 177 ELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQS-----DTCTEQERKLYIDIAINGIEQANHVLTDYLTFAKPSI 251
Cdd:COG5000 191 ELLRAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRkladkLEEDREDLERALDTIIRQVDRLKRIVDEFLDFARLPE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 252 EKEQTLQLEEELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHI 331
Cdd:COG5000 271 PQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRV 350
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1259951092 332 QLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPLIQKT 402
Cdd:COG5000 351 RIEVSDNGPGIPEEVLERIFEPFFTTKPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPLAEEA 421
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
173-398 |
9.32e-52 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 176.91 E-value: 9.32e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 173 RLQNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQ---SDTCTEQERKLYIDIAINGIEQANHVLTDYLTFAKP 249
Cdd:COG4191 128 ELQEQLVQSEKLAALGELAAGIAHEINNPLAAILGNAELLRrrlEDEPDPEELREALERILEGAERAAEIVRSLRAFSRR 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 250 SIEKEQTLQLEEELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKG--GDLYFTLVPD 327
Cdd:COG4191 208 DEEEREPVDLNELIDEALELLRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIDAMEEGegGRITISTRRE 287
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1259951092 328 HKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKE--KGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:COG4191 288 GDYVVISVRDNGPGIPPEVLERIFEPFFTTKPvgKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLPL 360
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
77-398 |
2.79e-50 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 172.40 E-value: 2.79e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 77 RLLLGGIGVFPSLIGSVLLFIVLLLTYKFFNRTSNRIKITLAIIYSLTYGFSWIPFFLSKVTNKTDYIPHIIVYELCSML 156
Cdd:COG0642 2 LLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 157 GTILILYLLHILQTQVRLQNELINAEKfhLIGEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERklYIDIAINGIEQA 236
Cdd:COG0642 82 LLLLLLLLLLLLLLLLALLLLLEEANE--AKSRFLANVSHELRTPLTAIRGYLELLLEELDEEQRE--YLETILRSADRL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 237 NHVLTDYLTFAKpsIEKE------QTLQLEEELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNC 310
Cdd:COG0642 158 LRLINDLLDLSR--LEAGklelepEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 311 IEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKE----KGTGLGMMVVFSVVQAMNGKIDIISEK 386
Cdd:COG0642 236 IKYTPEGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPsrrgGGTGLGLAIVKRIVELHGGTIEVESEP 315
|
330
....*....|..
gi 1259951092 387 GIGTTFLLTFPL 398
Cdd:COG0642 316 GKGTTFTVTLPL 327
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
173-400 |
2.10e-42 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 148.90 E-value: 2.10e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 173 RLQNELINAEKF-HLIGEMAASISHEIRNPLTSTKGFLQLLQSD-TCTEQERKLYIDIAINGIEQANHVLTDYLTFAKPS 250
Cdd:COG2205 1 ELEEALEELEELeRLKSEFLANVSHELRTPLTSILGAAELLLDEeDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 251 IEKE----QTLQLEEELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVP 326
Cdd:COG2205 81 SGKLslelEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1259951092 327 DHKHIQLYIKDTGVGMDSEQVKRLGSPFY----STKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPLIQ 400
Cdd:COG2205 161 EGDGVRISVSDNGPGIPEEELERIFERFYrgdnSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPLAE 238
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
189-401 |
1.07e-40 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 148.55 E-value: 1.07e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 189 EMAASISHEIRNPLTSTKGFLQLLQSDTC-TEQERKLYIDIAINGIEQANHVLTDYLTFAKpsIEKE------QTLQLEE 261
Cdd:COG5002 167 EFVANVSHELRTPLTSIRGYLELLLDGAAdDPEERREYLEIILEEAERLSRLVNDLLDLSR--LESGelklekEPVDLAE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 262 ELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVG 341
Cdd:COG5002 245 LLEEVVEELRPLAEEKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQVRISVRDTGIG 324
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1259951092 342 MDSEQVKRLGSPFY------STKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPLIQK 401
Cdd:COG5002 325 IPEEDLPRIFERFYrvdksrSRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPLARE 390
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
171-398 |
1.85e-39 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 148.58 E-value: 1.85e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 171 QVRLQNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKlYIDIAINGIEQANHVLTDYLTFAKPS 250
Cdd:PRK11360 374 RKRLQRRVARQERLAALGELVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQE-YLSVVLREVDRLNKVIDQLLEFSRPR 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 251 IEKEQTLQLEEELLHALSLI--TPLANLTNVRTHYIKQSTSFFIAGEKqkLNQCLLNILKNCIEAMPKGGDLYF-TLVPD 327
Cdd:PRK11360 453 ESQWQPVSLNALVEEVLQLFqtAGVQARVDFETELDNELPPIWADPEL--LKQVLLNILINAVQAISARGKIRIrTWQYS 530
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1259951092 328 HKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:PRK11360 531 DGQVAVSIEDNGCGIDPELLKKIFDPFFTTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLPI 601
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
174-399 |
7.93e-36 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 136.45 E-value: 7.93e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 174 LQNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIDIAINGIEQANHVLTDYLTFAKPSIEK 253
Cdd:PRK10364 224 LQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLA 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 254 EQTLQLEEELLHALSLITPLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQL 333
Cdd:PRK10364 304 LQAVDLNDLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKI 383
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1259951092 334 YIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPLI 399
Cdd:PRK10364 384 SVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPVN 449
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
294-398 |
6.23e-27 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 103.50 E-value: 6.23e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 294 GEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKE-----KGTGLGMMV 368
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKrsrkiGGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|
gi 1259951092 369 VFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLPL 110
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
294-398 |
1.22e-23 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 94.36 E-value: 1.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 294 GEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHkHIQLYIKDTGVGMDSEQVKRLGSPFYS---TKEKGTGLGMMVVF 370
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEGG-ELTLTVEDNGIGIPPEDLPRIFEPFSTadkRGGGGTGLGLSIVR 79
|
90 100
....*....|....*....|....*...
gi 1259951092 371 SVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:pfam02518 80 KLVELLGGTITVESEPGGGTTVTLTLPL 107
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
299-398 |
4.26e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 87.48 E-value: 4.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKE--KGTGLGMMVVFSVVQAM 376
Cdd:cd16943 4 LNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPvgEGTGLGLSLSYRIIQKH 83
|
90 100
....*....|....*....|..
gi 1259951092 377 NGKIDIISEKGIGTTFLLTFPL 398
Cdd:cd16943 84 GGTIRVASVPGGGTRFTIILPI 105
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
169-401 |
1.26e-20 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 93.97 E-value: 1.26e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 169 QTQ-VRLQNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIDIAINGIEQANHVLTDYLTFA 247
Cdd:PRK13837 431 ETErDALERRLEHARRLEAVGTLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQILAFG 510
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 248 KPSIEKEQTLQLEEELLHALSLITpLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTL--- 324
Cdd:PRK13837 511 RKGERNTKPFDLSELVTEIAPLLR-VSLPPGVELDFDQDQEPAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLsra 589
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 325 ------------VPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTF 392
Cdd:PRK13837 590 klrapkvlshgvLPPGRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYIDVQSTVGRGTRF 669
|
....*....
gi 1259951092 393 LLTFPLIQK 401
Cdd:PRK13837 670 DVYLPPSSK 678
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
299-397 |
3.97e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 82.43 E-value: 3.97e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAMPKGGDLYFTLVPDH---------------KHIQLYIKDTGVGMDSEQVKRLGSPFYSTKE--KG 361
Cdd:cd16919 1 LELAILNLAVNARDAMPEGGRLTIETSNQRvdadyalnyrdlipgNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKEvgKG 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 1259951092 362 TGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFP 397
Cdd:cd16919 81 TGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
299-397 |
5.37e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 81.67 E-value: 5.37e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAM----PKGGDLYFTLVP-DHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVV 373
Cdd:cd16920 1 IQQVLINLVRNGIEAMseggCERRELTIRTSPaDDRAVTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRSII 80
|
90 100
....*....|....*....|....
gi 1259951092 374 QAMNGKIDIISEKGIGTTFLLTFP 397
Cdd:cd16920 81 EAHGGRLSVESPAGGGATFQFTLP 104
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
173-399 |
6.06e-19 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 88.93 E-value: 6.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 173 RLQNELINAEK-FHLigemaASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLyIDIAINGieqANHVLT---DYLTFAK 248
Cdd:PRK15347 388 KQRAEQANKRKsEHL-----TTISHEIRTPLNGVLGALELLQNTPLTAEQMDL-ADTARQC---TLSLLAiinNLLDFSR 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 249 psIEKEQ-TLQLEE-ELLhalslitPL---ANLT-NVRTHYIKQSTSFFIAGE--------KQKLNQCLLNILKNCIEAM 314
Cdd:PRK15347 459 --IESGQmTLSLEEtALL-------PLldqAMLTiQGPAQSKSLTLRTFVGAHvplylhldSLRLRQILVNLLGNAVKFT 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 315 PKGGdlYFTLVPDHKHiQLY--IKDTGVGMDSEQVKRLGSPFY--STKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGT 390
Cdd:PRK15347 530 ETGG--IRLRVKRHEQ-QLCftVEDTGCGIDIQQQQQIFTPFYqaDTHSQGTGLGLTIASSLAKMMGGELTLFSTPGVGS 606
|
....*....
gi 1259951092 391 TFLLTFPLI 399
Cdd:PRK15347 607 CFSLVLPLN 615
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
169-400 |
6.10e-19 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 88.69 E-value: 6.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 169 QTQVRLQN---ELINAEkfhlIGEMAASISHEIRNPLTSTKGFLQLLQSD---TCTEQERKlYIDIAINGIEQANHVLTD 242
Cdd:COG4251 265 EEELEERTaelERSNEE----LEQFAYVASHDLREPLRKISGFSQLLEEDygdKLDEEGRE-YLERIRDAAERMQALIDD 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 243 YLTFAKpsIEKeQTLQLEE----ELLH-ALSLITPLANLTNVRTHYIKQSTsffIAGEKQKLNQCLLNILKNCIEAMPKG 317
Cdd:COG4251 340 LLAYSR--VGR-QELEFEPvdlnELLEeVLEDLEPRIEERGAEIEVGPLPT---VRGDPTLLRQVFQNLISNAIKYSRPG 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 318 --GDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFY----STKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTT 391
Cdd:COG4251 414 epPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQrlhsRDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEGAT 493
|
....*....
gi 1259951092 392 FLLTFPLIQ 400
Cdd:COG4251 494 FYFTLPKAP 502
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
178-397 |
4.51e-17 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 82.80 E-value: 4.51e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 178 LINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIDIAINGI----EQANHVLTDYLTFAKPSIEK 253
Cdd:PRK13557 154 LRQAQKMEALGQLTGGIAHDFNNLLQVMSGYLDVIQAALSHPDADRGRMARSVENIraaaERAATLTQQLLAFARKQRLE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 254 EQTLQL-----------EEELLHALSLITPLA-NLTNVRThyikQSTSFFIAgekqklnqcLLNILKNCIEAMPKGGDLY 321
Cdd:PRK13557 234 GRVLNLnglvsgmgelaERTLGDAVTIETDLApDLWNCRI----DPTQAEVA---------LLNVLINARDAMPEGGRVT 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 322 ---------------FTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKE--KGTGLGMMVVFSVVQAMNGKIDIIS 384
Cdd:PRK13557 301 irtrnveiededlamYHGLPPGRYVSIAVTDTGSGMPPEILARVMDPFFTTKEegKGTGLGLSMVYGFAKQSGGAVRIYS 380
|
250
....*....|...
gi 1259951092 385 EKGIGTTFLLTFP 397
Cdd:PRK13557 381 EVGEGTTVRLYFP 393
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
175-387 |
9.91e-16 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 78.96 E-value: 9.91e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 175 QNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKL--YIDIAINGIEQANHVLTDYLTFAKPSIE 252
Cdd:COG4192 421 QDELIQAAKMAVVGQTMTSLAHELNQPLNAMSMYLFSAKKALEQENYAQLptSLDKIEGLIERMDKIIKSLRQFSRKSDT 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 253 KEQTLQLEEELLHALSLitpLANLTNVRTHYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQ 332
Cdd:COG4192 501 PLQPVDLRQVIEQAWEL---VESRAKPQQITLHIPDDLMVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLR 577
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1259951092 333 LYIKDTGVGMDSeqVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIIS--EKG 387
Cdd:COG4192 578 VAISDNGNGWPL--VDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYLAStlERG 632
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
192-400 |
1.98e-15 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 78.48 E-value: 1.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 192 ASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIdiAINgieqaN------HVLTDYLTFAKpsIEKEQtLQLE----- 260
Cdd:PRK10841 452 ATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLVT--AMN-----NssslllKIISDILDFSK--IESEQ-LKIEprefs 521
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 261 --EELLHALSLITPLAnltnVRTH-----YIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGdLYFTLVPDHKHIQL 333
Cdd:PRK10841 522 prEVINHITANYLPLV----VKKRlglycFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGC-IVLHVRVDGDYLSF 596
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1259951092 334 YIKDTGVGMDSEQVKRLGSPFY---STKEK---GTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPLIQ 400
Cdd:PRK10841 597 RVRDTGVGIPAKEVVRLFDPFFqvgTGVQRnfqGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIPLYG 669
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
175-398 |
2.20e-15 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 78.24 E-value: 2.20e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 175 QNELINAEKFHliGEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIDIAINGIEQANHVLTDYLTFAKpsIEkE 254
Cdd:PRK09959 702 RNKAINATVAK--SQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDK--IE-S 776
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 255 QTLQLEEELLHALSLIT----PLANLTNVRTHYIKQSTSF----FIAGEKQKLNQCLLNILKNCIEAMPKGG-DLYFTLV 325
Cdd:PRK09959 777 GNYQLQPQWVDIPTLVQntchSFGAIAASKSIALSCSSTFpdhyLVKIDPQAFKQVLSNLLSNALKFTTEGAvKITTSLG 856
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 326 ---PDHKHIQLYIKDTGVGMDSEQVKRLGSPFYST----KEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:PRK09959 857 hidDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTsagrQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPV 936
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
192-398 |
1.64e-13 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 72.25 E-value: 1.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 192 ASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIDIAINGiEQANHVLTDYLTFAkpSIEKEQT-LQLEEELLHALSLI 270
Cdd:PRK11466 449 AAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSG-ESLLTILNDILDYS--AIEAGGKnVSVSDEPFEPRPLL 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 271 TPLANLTN--VRTHYIKQSTSF------FIAGEKQKLNQCLLNILKNCIEAMPKGgDLYFTLVPDHKHIQLYIKDTGVGM 342
Cdd:PRK11466 526 ESTLQLMSgrVKGRPIRLATDIaddlptALMGDPRRIRQVITNLLSNALRFTDEG-SIVLRSRTDGEQWLVEVEDSGCGI 604
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1259951092 343 DSEQVKRLGSPFY--STKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:PRK11466 605 DPAKLAEIFQPFVqvSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPL 662
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
299-398 |
1.64e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 66.36 E-value: 1.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAMPKGG-DLYFTLVPDHK-HIQLY--IKDTGVGMDSEQVKRLGSPF------YSTKEKGTGLGMMV 368
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEGEvTLRVSLEEEEEdGVQLRfsVEDTGIGIPEEQQARLFEPFsqadssTTRKYGGTGLGLAI 80
|
90 100 110
....*....|....*....|....*....|
gi 1259951092 369 VFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:cd16922 81 SKKLVELMGGDISVESEPGQGSTFTFTLPL 110
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
188-248 |
3.90e-13 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 63.77 E-value: 3.90e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1259951092 188 GEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIDIAINGIEQANHVLTDYLTFAK 248
Cdd:cd00082 5 GEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
306-397 |
5.35e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 65.00 E-value: 5.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 306 ILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTK-----EKGTGLGMMVVFSVVQAMNGKI 380
Cdd:cd16948 13 IVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGEngrnfQESTGMGLYLVKKLCDKLGHKI 92
|
90
....*....|....*..
gi 1259951092 381 DIISEKGIGTTFLLTFP 397
Cdd:cd16948 93 DVESEVGEGTTFTITFP 109
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
188-248 |
7.52e-13 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 62.97 E-value: 7.52e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1259951092 188 GEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKlYIDIAINGIEQANHVLTDYLTFAK 248
Cdd:smart00388 3 REFLANLSHELRTPLTAIRGYLELLLDTELSEEQRE-YLETILREAERLLRLINDLLDLSR 62
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
188-248 |
1.52e-12 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 62.23 E-value: 1.52e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1259951092 188 GEMAASISHEIRNPLTSTKGFLQLLQSDTCTEQERKlYIDIAINGIEQANHVLTDYLTFAK 248
Cdd:pfam00512 3 SEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQRE-YLETILRSAERLLRLINDLLDLSR 62
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
173-398 |
6.32e-12 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 66.41 E-value: 6.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 173 RLQNELINAEKFHligEMAASISHEIRNPLTSTKGFLQLLQSDtcteqERKLYIDIAINGIEQANHVLTDY--------L 244
Cdd:COG3290 178 RLEEELEGVKELA---EALRAQRHDFRNHLHTISGLLQLGEYD-----EALEYIDEISEELQELIDSLLSRignpvlaaL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 245 TFAKPSIEKEQTLQLEeelLHALSLITPLanltNVRTHyikqstsffiagekqKLNQCLLNILKNCIEAMPKGGDL---- 320
Cdd:COG3290 250 LLGKAARARERGIDLT---IDIDSDLPDL----PLSDT---------------DLVTILGNLLDNAIEAVEKLPEEerrv 307
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1259951092 321 YFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTK-EKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:COG3290 308 ELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTKlGEGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLPK 386
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
171-398 |
1.97e-11 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 64.72 E-value: 1.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 171 QVRLQNELINAEKFHLIGEMAASISHEIRNPLTSTKGFLQLLQSdTCTEQERKLYIDIAIngiEQANHV--LTDYLTF-A 247
Cdd:PRK11073 114 QRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSK-ALPDPALTEYTKVII---EQADRLrnLVDRLLGpQ 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 248 KPSIEKEQTL-QLEEELLHALSLITPlANLTNVR---------THYIKQstsffiagekqkLNQCLLNILKNCIEAM-PK 316
Cdd:PRK11073 190 RPGTHVTESIhKVAERVVQLVSLELP-DNVRLIRdydpslpelAHDPDQ------------IEQVLLNIVRNALQALgPE 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 317 GGDLYFTLVPDHK---HIQLY-------IKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDIISEK 386
Cdd:PRK11073 257 GGTITLRTRTAFQltlHGERYrlaaridIEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTSWP 336
|
250
....*....|..
gi 1259951092 387 GiGTTFLLTFPL 398
Cdd:PRK11073 337 G-HTEFSVYLPI 347
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
189-398 |
1.09e-10 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 63.33 E-value: 1.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 189 EMAASISHEIRNPLTSTKGFL-QLLQSDTCTEQerKLYIdiaiNGIEQ-ANHVLT---DYLTFAKPSIEKeqtLQLE--- 260
Cdd:PRK11107 295 EFLANMSHELRTPLNGVIGFTrQTLKTPLTPTQ--RDYL----QTIERsANNLLAiinDILDFSKLEAGK---LVLEnip 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 261 ----EELLHALSLITPLANLTNVR-THYIKQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGG---DLYFTLVPDHK-HI 331
Cdd:PRK11107 366 fslrETLDEVVTLLAHSAHEKGLElTLNIDPDVPDNVIGDPLRLQQIITNLVGNAIKFTESGNidiLVELRALSNTKvQL 445
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1259951092 332 QLYIKDTGVGMDSEQVKRLGSPF------YSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:PRK11107 446 EVQIRDTGIGISERQQSQLFQAFrqadasISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLPL 518
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
191-397 |
1.18e-10 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 62.87 E-value: 1.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 191 AASISHEIRNPLTS--TKGFLQLLQSDTCTEQERKLYidiaiNGIEQANH---VLTDYLTFAKPS----IEKEQTLQLEE 261
Cdd:PRK09835 266 SADIAHEIRTPITNliTQTEIALSQSRSQKELEDVLY-----SNLEELTRmakMVSDMLFLAQADnnqlIPEKKMLDLAD 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 262 ELLHALSLITPLANLTNVRTHYikQSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVG 341
Cdd:PRK09835 341 EVGKVFDFFEAWAEERGVELRF--VGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTP 418
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1259951092 342 MDSEQVKRLGSPFYST------KEKGTGLGMMVVFSVVQAMNGKIDIISEkGIGTTFLLTFP 397
Cdd:PRK09835 419 IAPEHLPRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVVAHKGTVAVTSD-ARGTRFVISLP 479
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
305-397 |
2.27e-10 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 62.24 E-value: 2.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 305 NILKNCIEAMPKGGDLYFTLVPDHKHIQLYI--KDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVVQAMNGKIDI 382
Cdd:PRK11086 440 NLIENALEAVGGEEGGEISVSLHYRNGWLHCevSDDGPGIAPDEIDAIFDKGYSTKGSNRGVGLYLVKQSVENLGGSIAV 519
|
90
....*....|....*
gi 1259951092 383 ISEKGIGTTFLLTFP 397
Cdd:PRK11086 520 ESEPGVGTQFFVQIP 534
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
299-397 |
2.39e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 57.16 E-value: 2.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNC---IEAMPKG-GDLYFTLVPDH-KHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGMMVVFSVV 373
Cdd:cd16944 5 ISQVLTNILKNAaeaIEGRPSDvGEVRIRVEADQdGRIVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGLAIVKKIM 84
|
90 100
....*....|....*....|....
gi 1259951092 374 QAMNGKIDIISEKGIGTTFLLTFP 397
Cdd:cd16944 85 EEHGGRISLSNREAGGACIRIILP 108
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
192-402 |
4.23e-10 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 61.18 E-value: 4.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 192 ASISHEIRNPLTSTKGFLQLLQSD------------TCTEQERKLyidiaiNG-IEQanhvltdYLTFAKpsIEKEQTLQ 258
Cdd:PRK11006 209 ANVSHELRTPLTVLQGYLEMMQDQplegalrekalhTMREQTQRM------EGlVKQ-------LLTLSK--IEAAPTID 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 259 LEEE-----LLH-----ALSLITPLANLTNVRTHYIKqstsffIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDH 328
Cdd:PRK11006 274 LNEKvdvpmMLRvlereAQTLSQGKHTITFEVDNSLK------VFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVP 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 329 KHIQLYIKDTGVGMDSEQVKRLGSPFY------STKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFP--LIQ 400
Cdd:PRK11006 348 QGAEFSVEDNGPGIAPEHIPRLTERFYrvdkarSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLPerLIA 427
|
..
gi 1259951092 401 KT 402
Cdd:PRK11006 428 KN 429
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
299-397 |
6.29e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 56.25 E-value: 6.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAMPKGG---------DLYFTLVpDHKH---IQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGTGLGM 366
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSGgeiilrtrtQRQVTLG-HPRHrlaLRVSVIDNGPGIPPDLQDTIFYPMVSGRENGTGLGL 79
|
90 100 110
....*....|....*....|....*....|.
gi 1259951092 367 MVVFSVVQAMNGKIDIISEKGiGTTFLLTFP 397
Cdd:cd16918 80 AIAQNIVSQHGGVIECDSQPG-HTVFSVSLP 109
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
193-398 |
6.68e-10 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 60.63 E-value: 6.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 193 SISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIDIAingiEQANHV--LTD-YLTFAK----PSIEKEQTLQLEEELLH 265
Cdd:PRK11100 262 TLTHELKSPLAAIRGAAELLQEDPPPEDRARFTGNIL----TQSARLqqLIDrLLELARleqrQELEVLEPVALAALLEE 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 266 ALSLITPLANLTNVRTHYIKQSTSffIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSE 345
Cdd:PRK11100 338 LVEAREAQAAAKGITLRLRPDDAR--VLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPDY 415
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1259951092 346 QVKRLGSPFYS-----TKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:PRK11100 416 ALPRIFERFYSlprpaNGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPR 473
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
299-397 |
9.86e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 55.67 E-value: 9.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFY------STKEKGTGLGMMVVFSV 372
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYrvdierCRNTGGTGLGLAIVKHV 80
|
90 100
....*....|....*....|....*
gi 1259951092 373 VQAMNGKIDIISEKGIGTTFLLTFP 397
Cdd:cd16952 81 MSRHDARLLIASELGKGSRFTCLFP 105
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
173-399 |
1.05e-09 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 60.34 E-value: 1.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 173 RLQNELINA--EKFHLIgemaASISHEIRNPLTSTKGFLQLLQSDTCTEQERKLYIDIAINGIEQANhVLTDYLTFAKps 250
Cdd:PRK11091 271 RYQDALEKAsrDKTTFI----STISHELRTPLNGIVGLSRILLDTELTAEQRKYLKTIHVSAITLGN-IFNDIIDMDK-- 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 251 IEKEQtLQLEEELLHALSLITPLANLTNVRTH------YIKQSTSF--FIAGEKQKLNQCLLNILKNCIEAMPKGGDLYF 322
Cdd:PRK11091 344 MERRK-LQLDNQPIDFTDFLADLENLSGLQAEqkglrfDLEPLLPLphKVITDGTRLRQILWNLISNAVKFTQQGGVTVR 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 323 TLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEK-------GTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLT 395
Cdd:PRK11091 423 VRYEEGDMLTFEVEDSGIGIPEDELDKIFAMYYQVKDShggkpatGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLT 502
|
....
gi 1259951092 396 FPLI 399
Cdd:PRK11091 503 IHAP 506
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
295-397 |
1.26e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 55.16 E-value: 1.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 295 EKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEK------GTGLGMMV 368
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSrnrasgGSGLGLAI 80
|
90 100 110
....*....|....*....|....*....|
gi 1259951092 369 VFSVVQAMNGKIDII-SEKGiGTTFLLTFP 397
Cdd:cd16946 81 CHNIALAHGGTISAEhSPLG-GLRLVLTLP 109
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
192-380 |
1.35e-09 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 59.65 E-value: 1.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 192 ASISHEIRNPLTSTKGFLQLLQSDT---CTEQERKLYIDIAI-----NGIEQANhvLTDY--LTFAKPSIEKEQTLQLE- 260
Cdd:PRK10549 245 ADISHELRTPLAVLRGELEAIQDGVrkfTPESVASLQAEVGTltklvDDLHQLS--LSDEgaLAYRKTPVDLVPLLEVAg 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 261 ---EELLHALSLitplanltNVRTHYIKQSTSFfiaGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKD 337
Cdd:PRK10549 323 gafRERFASRGL--------TLQLSLPDSATVF---GDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLTFAD 391
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1259951092 338 TGVGMDSEQVKRLGSPFYSTKEK------GTGLGMMVVFSVVQAMNGKI 380
Cdd:PRK10549 392 SAPGVSDEQLQKLFERFYRTEGSrnrasgGSGLGLAICLNIVEAHNGRI 440
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
330-398 |
2.36e-09 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 59.04 E-value: 2.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 330 HIQLYIKDTGVGMDSEQVKR------LGSP-------------------FySTKEK-----GTGLGMMVVFSVVQAMNGK 379
Cdd:COG0643 321 RVVIEVSDDGRGLDLEKIRAkaiekgLITAeeaaalsdeellelifapgF-STAEEvtdlsGRGVGMDVVKTNIEALGGT 399
|
90
....*....|....*....
gi 1259951092 380 IDIISEKGIGTTFLLTFPL 398
Cdd:COG0643 400 IEIESEPGKGTTFTLRLPL 418
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
299-394 |
1.47e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 52.07 E-value: 1.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAMPKGGDLYFTLVPDHK--HIQLYIKDTGVGMDSEQVKRLGSPFYSTKE--KGTGLGMMVVFSVVQ 374
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVENPRIRIAARRLggRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPvgKGTGLGLSISYGIVE 80
|
90 100
....*....|....*....|
gi 1259951092 375 AMNGKIDIISEKGIGTTFLL 394
Cdd:cd16976 81 EHGGRLSVANEEGAGARFTF 100
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
299-382 |
1.48e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 52.08 E-value: 1.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYS-----TKEKGTGLGMMVVFSVV 373
Cdd:cd16945 5 LRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSlprphSGQKSTGLGLAFVQEVA 84
|
....*....
gi 1259951092 374 QAMNGKIDI 382
Cdd:cd16945 85 QLHGGRITL 93
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
176-398 |
5.15e-08 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 54.61 E-value: 5.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 176 NELINAEKfhligEMAASISHEIRNPLTSTKGFLQLlqSDTCTEQERKlyidiAIN-GIEQANHVLTDYLTFAkpSIEKE 254
Cdd:PRK10604 206 NALIASKK-----QLIDGIAHELRTPLVRLRYRLEM--SDNLSAAESQ-----ALNrDIGQLEALIEELLTYA--RLDRP 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 255 Q-TLQLEE--------ELLHALSLITPLANLTNVRTHyikqsTSFFIAGEKQKLNQCLLNILKNCIEAmpKGGDLYFTLV 325
Cdd:PRK10604 272 QnELHLSEpdlpawlsTHLADIQAVTPEKTVRLDTPH-----QGDYGALDMRLMERVLDNLLNNALRY--AHSRVRVSLL 344
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1259951092 326 PDHKHIQLYIKDTGVGMDSEQVKRLGSPFY------STKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:PRK10604 345 LDGNQACLIVEDDGPGIPPEERERVFEPFVrldpsrDRATGGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWPV 423
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
294-380 |
1.15e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 49.71 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 294 GEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDhKHIQLYIKDTGVGMDSEQVKRLGSPFY---STKEKGTGLGMMVVF 370
Cdd:cd16940 9 GDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSAD-DGAVIRVEDNGPGIDEEELEALFERFYrsdGQNYGGSGLGLSIVK 87
|
90
....*....|
gi 1259951092 371 SVVQAMNGKI 380
Cdd:cd16940 88 RIVELHGGQI 97
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
305-397 |
1.81e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 48.82 E-value: 1.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 305 NILKNCIEAMPKGGD----LYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKE-KGTGLGMMVVFSVVQAMNGK 379
Cdd:cd16915 7 NLIDNALDALAATGApnkqVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKGqGERGIGLALVRQSVERLGGS 86
|
90
....*....|....*...
gi 1259951092 380 IDIISEKGIGTTFLLTFP 397
Cdd:cd16915 87 ITVESEPGGGTTFSIRIP 104
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
330-397 |
1.87e-07 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 50.66 E-value: 1.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 330 HIQLYIKDTGVGMDSEQVKR------------------------LGSPFYSTKEK-----GTGLGMMVVFSVVQAMNGKI 380
Cdd:cd16916 82 QVVIEVSDDGRGIDREKIREkaierglitadeaatlsddevlnlIFAPGFSTAEQvtdvsGRGVGMDVVKRSIESLGGTI 161
|
90
....*....|....*..
gi 1259951092 381 DIISEKGIGTTFLLTFP 397
Cdd:cd16916 162 EVESEPGQGTTFTIRLP 178
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
299-380 |
1.94e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 48.86 E-value: 1.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAMPKGGDLYFTLvpDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEK------GTGLGMMVVFSV 372
Cdd:cd16949 1 LARALENVLRNALRYSPSKILLDISQ--DGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSArdresgGTGLGLAIAERA 78
|
....*...
gi 1259951092 373 VQAMNGKI 380
Cdd:cd16949 79 IEQHGGKI 86
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
192-401 |
2.32e-07 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 52.26 E-value: 2.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 192 ASISHEIRNPLTSTK---GFLQLLQSDTCTEQERKL---YIDIAINGIEQANHVLTDYLTFAK---------------PS 250
Cdd:PRK09303 156 AMLAHDLRTPLTAASlalETLELGQIDEDTELKPALieqLQDQARRQLEEIERLITDLLEVGRtrwealrfnpqkldlGS 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 251 IEKEQTLQLEEELL-HALSLITPL-ANLTNVrthYIKQstsffiagekQKLNQCLLNILKNCIEAMPKGGDLyfTLVPDH 328
Cdd:PRK09303 236 LCQEVILELEKRWLaKSLEIQTDIpSDLPSV---YADQ----------ERIRQVLLNLLDNAIKYTPEGGTI--TLSMLH 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 329 K---HIQLYIKDTGVGMDSEQVKRLGSPFY----STKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPLIQK 401
Cdd:PRK09303 301 RttqKVQVSICDTGPGIPEEEQERIFEDRVrlprDEGTEGYGIGLSVCRRIVRVHYGQIWVDSEPGQGSCFHFTLPVYRG 380
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
299-397 |
7.25e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 47.32 E-value: 7.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 299 LNQCLLNILKNCIEAM----PKGGDLYFTLVPDHKhiQLYIKDTGVGMDSEQ-------VKRLGSPFYStkeKGTGLGMM 367
Cdd:cd16921 1 LGQVLTNLLGNAIKFRrprrPPRIEVGAEDVGEEW--TFYVRDNGIGIDPEYaekvfgiFQRLHSREEY---EGTGVGLA 75
|
90 100 110
....*....|....*....|....*....|
gi 1259951092 368 VVFSVVQAMNGKIDIISEKGIGTTFLLTFP 397
Cdd:cd16921 76 IVRKIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
311-401 |
8.77e-07 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 50.79 E-value: 8.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 311 IEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFySTKEKGTGLGMMVVFSVVQAMNGK---IDIISEKG 387
Cdd:COG2972 353 IEPKEGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEEL-SSKGEGRGIGLRNVRERLKLYYGEeygLEIESEPG 431
|
90
....*....|....
gi 1259951092 388 IGTTFLLTFPLIQK 401
Cdd:COG2972 432 EGTTVTIRIPLEEE 445
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
316-398 |
9.18e-07 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 50.67 E-value: 9.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 316 KGGDLYFTLVPDHKHIQLYIKDTGVGMDSEqvkrlgspfySTKEKGTGLGMMVVFSVVQAMNGKIDIISEKgiGTTFLLT 395
Cdd:COG3920 420 EGGRIRVSWRREDGRLRLTVSDNGVGLPED----------VDPPARKGLGLRLIRALVRQLGGTLELDRPE--GTRVRIT 487
|
...
gi 1259951092 396 FPL 398
Cdd:COG3920 488 FPL 490
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
294-395 |
9.52e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 47.51 E-value: 9.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 294 GEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKE------KGTGLGMM 367
Cdd:cd16947 16 ANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDsrnsakQGNGLGLT 95
|
90 100
....*....|....*....|....*...
gi 1259951092 368 VVFSVVQAMNGKIDIISEKGIGTTFLLT 395
Cdd:cd16947 96 ITKRLAESMGGSIYVNSKPYEKTVFTVT 123
|
|
| 5TM-5TMR_LYT |
pfam07694 |
5TMR of 5TMR-LYT; This entry represents the transmembrane region of the 5TM-LYT (5TM Receptors ... |
47-123 |
1.36e-06 |
|
5TMR of 5TMR-LYT; This entry represents the transmembrane region of the 5TM-LYT (5TM Receptors of the LytS-YhcK type).
Pssm-ID: 429599 Cd Length: 170 Bit Score: 47.95 E-value: 1.36e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1259951092 47 FDMRHIVLIVGTLTGGPIAGGSILVVLNIYRLLLGGIGVFPSLIGSVLLFIVLLLTYKFFNRTSNRIKITLAIIYSL 123
Cdd:pfam07694 45 ANTRAVGIVLAGLLGGPIVGLIAGLIAGLHRYFLGGFTALACGISTILAGLIAGLLHRRLKRRRRLISPLLAFLIGL 121
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
297-382 |
3.00e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 45.53 E-value: 3.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 297 QKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFYSTKEKGT-----GLGMMVVFS 371
Cdd:cd16975 3 LLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRsgghyGMGLYIAKN 82
|
90
....*....|.
gi 1259951092 372 VVQAMNGKIDI 382
Cdd:cd16975 83 LVEKHGGSLII 93
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
323-398 |
5.73e-06 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 47.31 E-value: 5.73e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1259951092 323 TLVPDHKHIQLYIKDTGVGMDSEQVKRlgspfystkeKGTGLGMMVvfSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:COG4585 186 TLEVDDGELTLTVRDDGVGFDPEAAPG----------GGLGLRGMR--ERAEALGGTLTIGSAPGGGTRVRATLPL 249
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
196-369 |
6.57e-06 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 48.11 E-value: 6.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 196 HEIRNPLTSTK---GFLQLLQSDtctEQERKLYIDIAINGIEQANHVLTDYLTFAK----PSIEKEQTLQLEEELLHALS 268
Cdd:PRK10337 246 HELRSPLAALKvqtEVAQLSDDD---PQARKKALLQLHAGIDRATRLVDQLLTLSRldslDNLQDVAEIPLEDLLQSAVM 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 269 LITPLANLTNVRTHYIKQSTSFFIAGekQKLNQCLL--NILKNCIEAMPKGGDLYFTLVPDHkhiqLYIKDTGVGMDSEQ 346
Cdd:PRK10337 323 DIYHTAQQAGIDVRLTLNAHPVIRTG--QPLLLSLLvrNLLDNAIRYSPQGSVVDVTLNARN----FTVRDNGPGVTPEA 396
|
170 180
....*....|....*....|....*.
gi 1259951092 347 VKRLGSPFYST--KEK-GTGLGMMVV 369
Cdd:PRK10337 397 LARIGERFYRPpgQEAtGSGLGLSIV 422
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
297-397 |
2.98e-05 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 42.86 E-value: 2.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 297 QKLNQCLLNILKNCIEAMPKGGDLYFTL-VPDHKHIQLYIKDTGVGMDSEQVKRL------GSPFYSTKEKGTGLGMMVV 369
Cdd:cd16925 3 EKYERVVLNLLSNAFKFTPDGGRIRCILeKFRLNRFLLTVSDSGPGIPPNLREEIferfrqGDGSSTRAHGGTGLGLSIV 82
|
90 100
....*....|....*....|....*...
gi 1259951092 370 FSVVQAMNGKIDIISEKGIGTTFLLTFP 397
Cdd:cd16925 83 KEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_ETR2_ERS2-EIN4-like |
cd16938 |
Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related ... |
290-395 |
5.50e-05 |
|
Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related domains; This family includes the histidine kinase-like ATPase domains (HATPase) of three out of the five receptors that recognize the plant hormone ethylene in Arabidopsis thaliana. These three proteins have been classified as belonging to subfamily 2: ETR2, ERS2, and EIN4. They lack most of the motifs characteristic of histidine kinases, and EIN4 is the only one in this group containing the conserved histidine that is phosphorylated in two-component and phosphorelay systems. This family also includes the HATPase domains of Escherichia coli RcsD phosphotransferase which is a component of the Rcs-signaling system, a complex multistep phosphorelay involving five proteins, and is involved in many transcriptional networks such as cell division, biofilm formation, and virulence, among others. Also included is Schizosaccharomyces pombe Mak3 (Phk1) which participates in a multi-step two-component related system which regulates H2O2-induced activation of the Sty1 stress-activated protein kinase pathway. Most proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a GAF sensor domain; most are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340415 [Multi-domain] Cd Length: 133 Bit Score: 42.83 E-value: 5.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 290 FFIAGEKQKLNQCLLNILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVG---MDSEQVK--------RLGSPF---- 354
Cdd:cd16938 3 DVVVGDERRVFQVLLHMLGNLLKMRNGGGNITFRVFLEGGSEDRSDRDWGPWrpsMSDESVEirfeveinDSGSPSiesa 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1259951092 355 ---------YSTKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLT 395
Cdd:cd16938 83 smrnslnrrYNLSELGEHLSFSICKQLVQLMGGNIWIVPGSGLGTTMSLL 132
|
|
| PRK10547 |
PRK10547 |
chemotaxis protein CheA; Provisional |
342-398 |
8.89e-05 |
|
chemotaxis protein CheA; Provisional
Pssm-ID: 236712 [Multi-domain] Cd Length: 670 Bit Score: 44.72 E-value: 8.89e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1259951092 342 MDSEQVKRL-GSPFYSTKEK-----GTGLGMMVVFSVVQAMNGKIDIISEKGIGTTFLLTFPL 398
Cdd:PRK10547 461 MSDEEVGMLiFAPGFSTAEQvtdvsGRGVGMDVVKRNIQEMGGHVEIQSKQGKGTTIRILLPL 523
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
327-389 |
1.28e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 40.90 E-value: 1.28e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1259951092 327 DHKHIQLYIKDTGVGMDSEQVKRLGSPFY----STKEKGTGLGMMVVFSVVQAMNGKIDIISEKGIG 389
Cdd:cd16950 27 EGNRTRIQVLDNGPGIAPEEVDELFQPFYrgdnARGTSGTGLGLAIVQRISDAHGGSLTLANRAGGG 93
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
305-397 |
2.40e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 37.37 E-value: 2.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 305 NILKNCIEAMPKGGDLYFTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPFY----STKEKGTGLGMMVVFSVVQAMNGKI 380
Cdd:cd16923 7 NLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYrgdnSRNTEGAGLGLSIAKAIIELHGGSA 86
|
90
....*....|....*..
gi 1259951092 381 DIISEkGIGTTFLLTFP 397
Cdd:cd16923 87 SAEYD-DNHDLFKVRLP 102
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
173-379 |
3.88e-03 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 39.18 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 173 RLQNELINAEKFhligemAASISHEIRNPLTSTKGFLQLLqsdtctEQERKLYIDIAINGIEQANHVLTDYLTFAKPSIE 252
Cdd:PRK10755 129 RLTSTLDQERLF------TADVAHELRTPLAGIRLHLELL------EKQHHIDVAPLIARLDQMMHTVEQLLQLARAGQS 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 253 ----KEQTLQLEEELlhalslITP----LANLTNVRTHYIK---QSTSFFIAGEKQKLNQCLLNILKNCIEAMPKGGDLY 321
Cdd:PRK10755 197 fssgHYQTVKLLEDV------ILPsqdeLSEMLEQRQQTLLlpeSAADITVQGDATLLRLLLRNLVENAHRYSPEGSTIT 270
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1259951092 322 FTLVPDHKHIQLYIKDTGVGMDSEQVKRLGSPF--YSTKEKGTGLGMMVVFSVVQAMNGK 379
Cdd:PRK10755 271 IKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFvrMDSRYGGIGLGLSIVSRITQLHHGQ 330
|
|
| |
