|
Name |
Accession |
Description |
Interval |
E-value |
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
3-234 |
1.81e-98 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 289.27 E-value: 1.81e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKI----SKMKREIGYLPQ 78
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVardpAEVRRRIGYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:COG1131 81 EPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTS 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 159 ALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSEnKLIIEITAKDQK 234
Cdd:COG1131 161 GLDPEARRELWELLRELAAEgKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARLLE-DVFLELTGEEAR 236
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
3-298 |
8.21e-88 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 264.28 E-value: 8.21e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-KMKREIGYLPQ--- 78
Cdd:COG4152 2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDpEDRRRIGYLPEerg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 -YPNffhwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPV 157
Cdd:COG4152 82 lYPK----MKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 158 SALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSENKLIIEITAkDQKWI 236
Cdd:COG4152 158 SGLDPVNVELLKDVIRELAaKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGRNTLRLEADG-DAGWL 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 237 dvvKKLPYVKDVEVIGLKVKVKVESiEVNKNLLLQNALEhKVDIIKFEVSNDTLEEIFLKLV 298
Cdd:COG4152 237 ---RALPGVTVVEEDGDGAELKLED-GADAQELLRALLA-RGPVREFEEVRPSLNEIFIEVV 293
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
3-204 |
2.02e-74 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 225.74 E-value: 2.02e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK----MKREIGYLPQ 78
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKepeeVKRRIGYLPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLtfmgqlsglkkeelsksipkilekvglrgeenskvgTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:cd03230 81 EPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLILDEPTS 124
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1261024142 159 ALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDG 204
Cdd:cd03230 125 GLDPESRREFWELLRELKKEgKTILLSSHILEEAERLCDRVAILNNG 171
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
3-204 |
3.34e-71 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 218.99 E-value: 3.34e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGeCVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE----IGYLPQ 78
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKlrrrIGYLPQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:cd03264 80 EFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTA 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1261024142 159 ALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:cd03264 160 GLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKG 205
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
3-224 |
4.11e-70 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 217.42 E-value: 4.11e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM----KREIGYLPQ 78
Cdd:COG4555 2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEpreaRRQIGVLPD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:COG4555 82 ERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTN 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 159 ALDPIGRREVLNLIEEIKK-DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSENKL 224
Cdd:COG4555 162 GLDVMARRLLREILRALKKeGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEENL 228
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
3-205 |
2.98e-67 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 209.28 E-value: 2.98e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKI----SKMKREIGYL 76
Cdd:cd03263 1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIrtdrKAARQSLGYC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:cd03263 81 PQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1261024142 157 VSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDGT 205
Cdd:cd03263 161 TSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGK 209
|
|
| GldA_ABC_ATP |
TIGR03522 |
gliding motility-associated ABC transporter ATP-binding subunit GldA; Members of this protein ... |
1-294 |
2.40e-65 |
|
gliding motility-associated ABC transporter ATP-binding subunit GldA; Members of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldA is an ABC transporter ATP-binding protein (pfam00005) linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldA abolish the gliding phenotype. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.
Pssm-ID: 132561 [Multi-domain] Cd Length: 301 Bit Score: 206.93 E-value: 2.40e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK----MKREIGYL 76
Cdd:TIGR03522 1 MSIRVSSLTKLYGTQNALDEVSFEAQKGRIVGFLGPNGAGKSTTMKIITGYLPPDSGSVQVCGEDVLQnpkeVQRNIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:TIGR03522 81 PEHNPLYLDMYVREYLQFIAGIYGMKGQLLKQRVEEMIELVGLRPEQHKKIGQLSKGYRQRVGLAQALIHDPKVLILDEP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 157 VSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSENKLIIEIT-AKDQKW 235
Cdd:TIGR03522 161 TTGLDPNQLVEIRNVIKNIGKDKTIILSTHIMQEVEAICDRVIIINKGKIVADKKLDELSAANKKQVIEVEFEeQIDLQL 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 236 IDVVKKLPYVKDVEviGLKVKVKVESIEVNKNLLLQNALEHKVDIIKFEVSNDTLEEIF 294
Cdd:TIGR03522 241 FETLEEISSVKNTG--GNTWKLTFETPNDTRPEIFKLAQQKGLKLISLQQNEKNLEQVF 297
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
3-209 |
3.04e-64 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 200.91 E-value: 3.04e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK---REIGYLPQY 79
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIealRRIGALIEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 80 PNFFHWMTARETLTFMGQLSGLKKEElsksIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:cd03268 81 PGFYPNLTARENLRLLARLLGIRKKR----IDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNG 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 160 LDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIED 209
Cdd:cd03268 157 LDPDGIKELRELILSLRDQgITVLISSHLLSEIQKVADRIGIINKGKLIEE 207
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
10-297 |
1.78e-60 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 194.53 E-value: 1.78e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 10 KSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKI----SKMKREIGYLPQYPNFFHW 85
Cdd:TIGR01188 1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVvrepRKVRRSIGIVPQYASVDED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 86 MTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGR 165
Cdd:TIGR01188 81 LTGRENLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 166 REVLNLIEEIKK-DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSENklIIEITAKDQKWIDVV----- 239
Cdd:TIGR01188 161 RAIWDYIRALKEeGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLGKD--TLESRPRDIQSLKVEvsmli 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 240 ----KKLPYVKDVEVIGLKVKVKVESIEVNKNLLLQNALEHKVDIIKFEVSNDTLEEIFLKL 297
Cdd:TIGR01188 239 aelgETGLGLLAVTVDSDRIKILVPDGDETVPEIVEAAIRNGIRIRSISTERPSLDDVFLKL 300
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
3-218 |
4.01e-60 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 199.36 E-value: 4.01e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF-----KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK------- 70
Cdd:COG1123 261 LEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSrrslrel 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 -REIGYLPQYPN--FFHWMTARETLTF-MGQLSGLKKEELSKSIPKILEKVGLRGE-ENSKVGTFSGGMKQRLGIAQALL 145
Cdd:COG1123 341 rRRVQMVFQDPYssLNPRMTVGDIIAEpLRLHGLLSRAERRERVAELLERVGLPPDlADRYPHELSGGQRQRVAIARALA 420
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 146 HKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:COG1123 421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRELglTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFAN 495
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
3-215 |
1.03e-59 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 189.89 E-value: 1.03e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK----MKREIGYLPQ 78
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVRepreVRRRIGIVFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:cd03265 81 DLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTI 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 159 ALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:cd03265 161 GLDPQTRAHVWEYIEKLKEefGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
3-207 |
9.67e-58 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 184.41 E-value: 9.67e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-IGYLPQ--- 78
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNrIGYLPEerg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 -YPNffhwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPV 157
Cdd:cd03269 81 lYPK----MKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPF 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 158 SALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKI 207
Cdd:cd03269 157 SGLDPVNVELLKDVIRELArAGKTVILSTHQMELVEELCDRVLLLNKGRAV 207
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
3-204 |
9.79e-56 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 179.25 E-value: 9.79e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQY 79
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVppeRRNIGMVFQD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 80 PNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:cd03259 81 YALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1261024142 160 LDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:cd03259 161 LDAKLREELREELKELQRelGITTIYVTHDQEEALALADRIAVMNEG 207
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
3-204 |
2.33e-55 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 179.51 E-value: 2.33e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYLPQYPNf 82
Cdd:COG1121 7 IELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRIGYVPQRAE- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 FHW---MTARETLTF-----MGQLSGLKKEELSKsIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:COG1121 86 VDWdfpITVRDVVLMgrygrRGLFRRPSRADREA-VDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLLLD 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIKK-DTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:COG1121 165 EPFAGVDAATEEALYELLRELRReGKTILVVTHDLGAVREYFDRVLLLNRG 215
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-252 |
3.38e-54 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 179.64 E-value: 3.38e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKR----EIGYL 76
Cdd:PRK13536 40 VAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARlaraRIGVV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:PRK13536 120 PQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEP 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 157 VSALDPIGRrevlNLIEE-----IKKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSENKlIIEITAK 231
Cdd:PRK13536 200 TTGLDPHAR----HLIWErlrslLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALIDEHIGCQ-VIEIYGG 274
|
250 260
....*....|....*....|.
gi 1261024142 232 DQKWIDVVKKlPYVKDVEVIG 252
Cdd:PRK13536 275 DPHELSSLVK-PYARRIEVSG 294
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
3-218 |
5.97e-54 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 175.21 E-value: 5.97e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF-KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYL 76
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNlrelrRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPN--FFHwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:COG1122 81 FQNPDdqLFA-PTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLD 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:COG1122 160 EPTAGLDPRGRRELLELLKRLNKEgKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSD 224
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-193 |
1.88e-53 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 174.89 E-value: 1.88e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSF----KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYL 76
Cdd:COG1116 6 PALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPDRGVV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:COG1116 86 FQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLLMDEP 165
|
170 180 190
....*....|....*....|....*....|....*....
gi 1261024142 157 VSALDPIGRREVLNLIEEI--KKDTTILLSTHilsDAEE 193
Cdd:COG1116 166 FGALDALTRERLQDELLRLwqETGKTVLFVTH---DVDE 201
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
3-225 |
2.94e-53 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 173.84 E-value: 2.94e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK--------REIG 74
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSeaelyrlrRRMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHWMTARETLTF-MGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:cd03261 81 MLFQSGALFDSLTVFENVAFpLREHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLY 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELlqRNSENKLI 225
Cdd:cd03261 161 DEPTAGLDPIASGVIDDLIRSLKKelGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL--RASDDPLV 232
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-192 |
3.44e-52 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 169.97 E-value: 3.44e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK----MKREIGYL 76
Cdd:COG4133 1 MMLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDaredYRRRLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKEELSksIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:COG4133 81 GHADGLKPELTVRENLRFWAALYGLRADREA--IDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEP 158
|
170 180 190
....*....|....*....|....*....|....*..
gi 1261024142 157 VSALDPIGRREVLNLIEE-IKKDTTILLSTHILSDAE 192
Cdd:COG4133 159 FTALDAAGVALLAELIAAhLARGGAVLLTTHQPLELA 195
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
3-216 |
4.50e-52 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 171.38 E-value: 4.50e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYLP 77
Cdd:COG1120 2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSrrelaRRIAYVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPNF-FHwMTARET-----LTFMGQLSGLKKEELSKsIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLI 151
Cdd:COG1120 82 QEPPApFG-LTVRELvalgrYPHLGLFGRPSAEDREA-VEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 152 VMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:COG1120 160 LLDEPTSHLDLAHQLEVLELLRRLARErgRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVL 226
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
3-201 |
1.22e-51 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 169.19 E-value: 1.22e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGK----IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYLPQ 78
Cdd:cd03293 1 LEVRNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPDRGYVFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:cd03293 81 QDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEPFS 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1261024142 159 ALDPIGR----REVLNLIEEIKKdtTILLSTHILSDAEEICERFVII 201
Cdd:cd03293 161 ALDALTReqlqEELLDIWRETGK--TVLLVTHDIDEAVFLADRVVVL 205
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
3-215 |
1.84e-51 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 169.47 E-value: 1.84e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK--------REI 73
Cdd:COG3638 3 LELRNLSKRYPgGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRgralrrlrRRI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 GYLPQYPNFFHWMTARET-LT-FMGQLSGLK-------KEELSKSIpKILEKVGLRGEENSKVGTFSGGMKQRLGIAQAL 144
Cdd:COG3638 83 GMIFQQFNLVPRLSVLTNvLAgRLGRTSTWRsllglfpPEDRERAL-EALERVGLADKAYQRADQLSGGQQQRVAIARAL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 145 LHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:COG3638 162 VQEPKLILADEPVASLDPKTARQVMDLLRRIarEDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAEL 234
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
3-204 |
2.24e-51 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 168.32 E-value: 2.24e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGK----IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE----IG 74
Cdd:cd03266 2 ITADALTKRFRDVkktvQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEarrrLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:cd03266 82 FVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLD 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDG 204
Cdd:cd03266 162 EPTTGLDVMATRALREFIRQLRALgKCILFSTHIMQEVERLCDRVVVLHRG 212
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
3-209 |
8.12e-51 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 167.30 E-value: 8.12e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKI----AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-------- 70
Cdd:cd03257 2 LEVKNLSVSFPTGGgsvkALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSrrlrkirr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 REIGYLPQYP----NFfhWMTARETL--TFMGQLSGLKKEELSKSIPKILEKVGLRGE-ENSKVGTFSGGMKQRLGIAQA 143
Cdd:cd03257 82 KEIQMVFQDPmsslNP--RMTIGEQIaePLRIHGKLSKKEARKEAVLLLLVGVGLPEEvLNRYPHELSGGQRQRVAIARA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIED 209
Cdd:cd03257 160 LALNPKLLIADEPTSALDVSVQAQILDLLKKLQEelGLTLLFITHDLGVVAKIADRVAVMYAGKIVEE 227
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
3-204 |
1.20e-50 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 166.81 E-value: 1.20e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-KMKREIGYLPQYPN 81
Cdd:TIGR03740 1 LETKNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPWTrKDLHKIGSLIESPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 82 FFHWMTARETLTFMGQLSGLKKEElsksIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:TIGR03740 81 LYENLTARENLKVHTTLLGLPDSR----IDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILDEPTNGLD 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1261024142 162 PIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDG 204
Cdd:TIGR03740 157 PIGIQELRELIRSFPEQgITVILSSHILSEVQQLADHIGIISEG 200
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
4-205 |
1.54e-50 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 166.10 E-value: 1.54e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYL 76
Cdd:cd03225 1 ELKNLSFSYPDgaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSlkelrRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPN--FFHwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:cd03225 81 FQNPDdqFFG-PTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLD 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGT 205
Cdd:cd03225 160 EPTAGLDPAGRRELLELLKKLKAEgKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
3-210 |
2.22e-50 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 165.99 E-value: 2.22e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-GKI---AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-------- 70
Cdd:COG1136 5 LELRNLTKSYGtGEGevtALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSerelarlr 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 -REIGYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPS 149
Cdd:COG1136 85 rRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPK 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 150 LIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHilsDAE--EICERFVIIKDGTKIEDT 210
Cdd:COG1136 165 LILADEPTGNLDSKTGEEVLELLRELNRElgTTIVMVTH---DPElaARADRVIRLRDGRIVSDE 226
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
3-218 |
4.83e-50 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 172.78 E-value: 4.83e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNA---GEVLLNGIKISKMK-----RE 72
Cdd:COG1123 5 LEVRDLSVRYPGgdVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGrisGEVLLDGRDLLELSealrgRR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 73 IGYLPQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLI 151
Cdd:COG1123 85 IGMVFQDPmTQLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLL 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 152 VMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:COG1123 165 IADEPTTALDVTTQAEILDLLRELQRErgTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAA 233
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
3-218 |
5.70e-50 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 167.67 E-value: 5.70e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE----IGYLPQ 78
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHarqrVGVVPQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:PRK13537 88 FDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTT 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 159 ALDPIGRrevlNLIEE-----IKKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:PRK13537 168 GLDPQAR----HLMWErlrslLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIES 228
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
3-218 |
7.50e-50 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 165.36 E-value: 7.50e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF----KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREI 73
Cdd:COG1124 2 LEVRNLSVSYgqggRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRrrrkaFRRRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 GYLPQYP----NFFHwmTARETLTFMGQLSGLKKEElsKSIPKILEKVGLRGEE-NSKVGTFSGGMKQRLGIAQALLHKP 148
Cdd:COG1124 82 QMVFQDPyaslHPRH--TVDRILAEPLRIHGLPDRE--ERIAELLEQVGLPPSFlDRYPHQLSGGQRQRVAIARALILEP 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 149 SLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:COG1124 158 ELLLLDEPTSALDVSVQAEILNLLKDLREErgLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAG 229
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
3-204 |
1.73e-49 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 164.28 E-value: 1.73e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK--------REI 73
Cdd:cd03256 1 IEVENLSKTYPnGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKgkalrqlrRQI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 GYLPQYPNFFHWMTARETL---------TFMGQLSGLKKEELSKSIpKILEKVGLRGEENSKVGTFSGGMKQRLGIAQAL 144
Cdd:cd03256 81 GMIFQQFNLIERLSVLENVlsgrlgrrsTWRSLFGLFPKEEKQRAL-AALERVGLLDKAYQRADQLSGGQQQRVAIARAL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 145 LHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:cd03256 160 MQQPKLILADEPVASLDPASSRQVMDLLKRInrEEGITVIVSLHQVDLAREYADRIVGLKDG 221
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
3-205 |
1.79e-49 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 161.97 E-value: 1.79e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM-------KREIGY 75
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLedelpplRRRIGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTARETLTFmgqlsglkkeelsksipkilekvGLrgeenskvgtfSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:cd03229 81 VFQDFALFPHLTVLENIAL-----------------------GL-----------SGGQQQRVALARALAMDPDVLLLDE 126
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 156 PVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGT 205
Cdd:cd03229 127 PTSALDPITRREVRALLKSLQAQlgITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
3-204 |
4.12e-49 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 162.66 E-value: 4.12e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKI----AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-------- 70
Cdd:cd03255 1 IELKNLSKTYGGGGekvqALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSekelaafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 -REIGYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPS 149
Cdd:cd03255 81 rRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 150 LIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAeEICERFVIIKDG 204
Cdd:cd03255 161 IILADEPTGNLDSETGKEVMELLRELNKEagTTIVVVTHDPELA-EYADRIIELRDG 216
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
3-225 |
2.01e-48 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 161.30 E-value: 2.01e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK--------REIG 74
Cdd:COG1127 6 IEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSekelyelrRRIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHWMTARETLTF-MGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:COG1127 86 MLFQGGALFDSLTVFENVAFpLREHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILLY 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELlqRNSENKLI 225
Cdd:COG1127 166 DEPTAGLDPITSAVIDELIRELRDelGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEEL--LASDDPWV 237
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
4-202 |
3.30e-48 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 160.01 E-value: 3.30e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYLPQYPNfF 83
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRIGYVPQRRS-I 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 84 HW---MTARET-----LTFMGQLSGLKKEELSKsIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:cd03235 80 DRdfpISVRDVvlmglYGHKGLFRRLSKADKAK-VDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDE 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1261024142 156 PVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIK 202
Cdd:cd03235 159 PFAGVDPKTQEDIYELLRELRREgMTILVVTHDLGLVLEYFDRVLLLN 206
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
3-234 |
2.61e-47 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 158.62 E-value: 2.61e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG-KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-----KMKREIGYL 76
Cdd:cd03295 1 IEFENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIReqdpvELRRKIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEE--NSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:cd03295 81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDPAEfaDRYPHELSGGQQQRVGVARALAADPPLLLMD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 155 EPVSALDPIGR----REVLNLIEEIKKdtTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLqRNSENKLIIEITA 230
Cdd:cd03295 161 EPFGALDPITRdqlqEEFKRLQQELGK--TIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEIL-RSPANDFVAEFVG 237
|
....
gi 1261024142 231 KDQK 234
Cdd:cd03295 238 ADRL 241
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
3-197 |
7.09e-47 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 159.83 E-value: 7.09e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF---KGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNA---GEVLLNGIKISKMK----- 70
Cdd:COG0444 2 LEVRNLKVYFptrRGVVkAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPGitsGEILFDGEDLLKLSekelr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 ----REIGYLPQYPnffhwMTA-----------RETLTFMGqlsGLKKEELSKSIPKILEKVGLRGEE---NSKVGTFSG 132
Cdd:COG0444 82 kirgREIQMIFQDP-----MTSlnpvmtvgdqiAEPLRIHG---GLSKAEARERAIELLERVGLPDPErrlDRYPHELSG 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 133 GMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICER 197
Cdd:COG0444 154 GMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRelGLAILFITHDLGVVAEIADR 220
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
3-209 |
1.23e-46 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 156.57 E-value: 1.23e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVI---SDIIN--PNAGEVLLNG-------IKISKMK 70
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLnrlNDLIPgaPDEGEVLLDGkdiydldVDVLELR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 REIGYLPQYPNFFHwMTARETLTFMGQLSGLK-KEELSKSIPKILEKVGLRGEENSK--VGTFSGGMKQRLGIAQALLHK 147
Cdd:cd03260 81 RRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIKlKEELDERVEEALRKAALWDEVKDRlhALGLSGGQQQRLCLARALANE 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 148 PSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDGTKIED 209
Cdd:cd03260 160 PEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEF 221
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
4-205 |
9.99e-46 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 152.59 E-value: 9.99e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYLPQ 78
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSpkelaRKIAYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 ypnffhwmtaretltfmgqlsglkkeelsksipkILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:cd03214 81 ----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTS 126
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1261024142 159 ALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFVIIKDGT 205
Cdd:cd03214 127 HLDIAHQIELLELLRRLARERgkTVVMVLHDLNLAARYADRVILLKDGR 175
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
4-205 |
1.88e-45 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 151.24 E-value: 1.88e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM-----KREIGYLPQ 78
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLpleelRRRIGYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 ypnffhwmtaretltfmgqlsglkkeelsksipkilekvglrgeenskvgtFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:cd00267 81 ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1261024142 159 ALDPIGRREVLNLIEEI-KKDTTILLSTHILSDAEEICERFVIIKDGT 205
Cdd:cd00267 110 GLDPASRERLLELLRELaEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
3-214 |
5.58e-45 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 152.59 E-value: 5.58e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK------REIGYL 76
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPpheiarLGIGRT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETL----------TFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLH 146
Cdd:cd03219 81 FQIPRLFPELTVLENVmvaaqartgsGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 147 KPSLIVMDEPVSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITE 214
Cdd:cd03219 161 DPKLLLLDEPAAGLNPEETEELAELIRELReRGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDE 229
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
3-210 |
5.92e-45 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 152.13 E-value: 5.92e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK--------REI 73
Cdd:COG2884 2 IRFENVSKRYPgGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKrreipylrRRI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 GYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:COG2884 82 GVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEI-KKDTTILLSTHilsdAEEICERF----VIIKDGTKIEDT 210
Cdd:COG2884 162 DEPTGNLDPETSWEIMELLEEInRRGTTVLIATH----DLELVDRMpkrvLELEDGRLVRDE 219
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
3-205 |
6.10e-45 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 151.51 E-value: 6.10e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYLP 77
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPppewrRQVAYVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPNFFHwMTARETLTFMGQLSGLKKEElsKSIPKILEKVGLRGE-ENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:COG4619 81 QEPALWG-GTVRDNLPFPFQLRERKFDR--ERALELLERLGLPPDiLDKPVERLSGGERQRLALIRALLLQPDVLLLDEP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 157 VSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGT 205
Cdd:COG4619 158 TSALDPENTRRVEELLREYlaEEGRAVLWVSHDPEQIERVADRVLTLEAGR 208
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
3-208 |
1.47e-44 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 154.87 E-value: 1.47e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQ- 78
Cdd:COG3842 6 LELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLppeKRNVGMVFQd 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHwMTARETLTFmG-QLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPV 157
Cdd:COG3842 86 YALFPH-LTVAENVAF-GlRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 158 SALDPIGRREvlnLIEEIKK-----DTTILLSTHilsDAEE---ICERFVIIKDGtKIE 208
Cdd:COG3842 164 SALDAKLREE---MREELRRlqrelGITFIYVTH---DQEEalaLADRIAVMNDG-RIE 215
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
3-219 |
2.06e-43 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 148.36 E-value: 2.06e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAvnNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQY 79
Cdd:COG3840 2 LRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALppaERPVSMLFQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 80 PNFFHWMTARETLTFmGQLSGLK--KEELSKsIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPV 157
Cdd:COG3840 80 NNLFPHLTVAQNIGL-GLRPGLKltAEQRAQ-VEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPF 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 158 SALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRN 219
Cdd:COG3840 158 SALDPALRQEMLDLVDELCRERglTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGE 221
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
3-207 |
2.79e-43 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 148.65 E-value: 2.79e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKreigylP----- 77
Cdd:COG0411 5 LEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLP------Phriar 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 -------QYPNFFHWMTARETL----------TFMGQLSGLKK-----EELSKSIPKILEKVGLRGEENSKVGTFSGGMK 135
Cdd:COG0411 79 lgiartfQNPRLFPELTVLENVlvaaharlgrGLLAALLRLPRarreeREARERAEELLERVGLADRADEPAGNLSYGQQ 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 136 QRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKI 207
Cdd:COG0411 159 RRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDErgITILLIEHDMDLVMGLADRIVVLDFGRVI 232
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
3-216 |
4.08e-43 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 147.73 E-value: 4.08e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGK----IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-------- 70
Cdd:cd03258 2 IELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSgkelrkar 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 REIGYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSL 150
Cdd:cd03258 82 RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 151 IVMDEPVSALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:cd03258 162 LLCDEATSALDPETTQSILALLRDINRELglTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVF 229
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
2-217 |
8.33e-43 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 147.79 E-value: 8.33e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFkgkIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---------KRE 72
Cdd:cd03294 27 KEEILKKTGQT---VGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMsrkelrelrRKK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 73 IGYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIV 152
Cdd:cd03294 104 ISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILL 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 153 MDEPVSALDPIGRRE----VLNLIEEIKKdtTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:cd03294 184 MDEAFSALDPLIRREmqdeLLRLQAELQK--TIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILT 250
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
3-211 |
1.05e-42 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 146.68 E-value: 1.05e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-------KMKREIGY 75
Cdd:COG1126 2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTdskkdinKLRRKVGM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTARETLTfMGQLS--GLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:COG1126 82 VFQQFNLFPHLTVLENVT-LAPIKvkKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLF 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTT 211
Cdd:COG1126 161 DEPTSALDPELVGEVLDVMRDLAKEgMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGP 219
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-204 |
1.35e-42 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 146.33 E-value: 1.35e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM------KREIG 74
Cdd:COG1137 2 MTLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLpmhkraRLGIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:COG1137 82 YLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFILLD 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:COG1137 162 EPFAGVDPIAVADIQKIIRHLKeRGIGVLITDHNVRETLGICDRAYIISEG 212
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
3-217 |
1.44e-42 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 146.15 E-value: 1.44e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM------KREIGYL 76
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLpmhkraRLGIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:cd03218 81 PQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEP 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 157 VSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:cd03218 161 FAGVDPIAVQDIQKIIKILKdRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAA 222
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
3-216 |
1.61e-42 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 146.27 E-value: 1.61e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM------KREIGYL 76
Cdd:TIGR04406 2 LVAENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLpmheraRLGIGYL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSG-LKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:TIGR04406 82 PQEASIFRKLTVEENIMAVLEIRKdLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDE 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 156 PVSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:TIGR04406 162 PFAGVDPIAVGDIKKIIKHLKeRGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEIV 223
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
3-219 |
2.85e-42 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 153.00 E-value: 2.85e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGY 75
Cdd:COG4987 334 LELEDVSFRYPGagRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDdlrrrIAV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHwMTARETLTFM-GQLSglkKEELSKSipkiLEKVGL----RGEE---NSKVG----TFSGGMKQRLGIAQA 143
Cdd:COG4987 414 VPQRPHLFD-TTLRENLRLArPDAT---DEELWAA----LERVGLgdwlAALPdglDTWLGeggrRLSGGERRRLALARA 485
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRN 219
Cdd:COG4987 486 LLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLER-MDRILVLEDGRIVEQGTHEELLAQN 560
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
3-204 |
3.35e-42 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 144.59 E-value: 3.35e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIK-------ISKMKREIGY 75
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKltddkknINELRQKVGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTARETLTF-MGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:cd03262 81 VFQQFNLFPHLTVLENITLaPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDG 204
Cdd:cd03262 161 EPTSALDPELVGEVLDVMKDLAEEgMTMVVVTHEMGFAREVADRVIFMDDG 211
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
3-204 |
6.98e-42 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 142.14 E-value: 6.98e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKI--AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGY 75
Cdd:cd03228 1 IEFKNVSFSYPGRPkpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLEslrknIAY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHwMTARETLtfmgqlsglkkeelsksipkilekvglrgeenskvgtFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:cd03228 81 VPQDPFLFS-GTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILILDE 122
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1261024142 156 PVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAeEICERFVIIKDG 204
Cdd:cd03228 123 ATSALDPETEALILEALRALAKGKTVIVIAHRLSTI-RDADRIIVLDDG 170
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
20-204 |
1.08e-41 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 143.20 E-value: 1.08e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 20 NFSMELQ---SGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG---------IKISKMKREIGYLPQYPNFFHWMT 87
Cdd:cd03297 12 DFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGtvlfdsrkkINLPPQQRKIGLVFQQYALFPHLN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 88 ARETLTFmgqlsGLKKEELSK---SIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIG 164
Cdd:cd03297 92 VRENLAF-----GLKRKRNREdriSVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRAL 166
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1261024142 165 RREVLNLIEEIKKDTTI--LLSTHILSDAEEICERFVIIKDG 204
Cdd:cd03297 167 RLQLLPELKQIKKNLNIpvIFVTHDLSEAEYLADRIVVMEDG 208
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
3-218 |
1.08e-41 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 146.76 E-value: 1.08e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGK----IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-------- 70
Cdd:COG1135 2 IELENLSKTFPTKggpvTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSerelraar 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 REIGYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSL 150
Cdd:COG1135 82 RKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKV 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 151 IVMDEPVSALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:COG1135 162 LLCDEATSALDPETTRSILDLLKDINRELglTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFAN 231
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
3-219 |
1.19e-41 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 152.68 E-value: 1.19e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGY 75
Cdd:COG2274 474 IELENVSFRYPGdsPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPAslrrqIGV 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHwMTARETLTFMG------------QLSGLkkEELSKSIPKILE-KVGLRGeenskvGTFSGGMKQRLGIAQ 142
Cdd:COG2274 554 VLQDVFLFS-GTIRENITLGDpdatdeeiieaaRLAGL--HDFIEALPMGYDtVVGEGG------SNLSGGQRQRLAIAR 624
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 143 ALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAeEICERFVIIKDGTKIEDTTITELLQRN 219
Cdd:COG2274 625 ALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAHRLSTI-RLADRIIVLDKGRIVEDGTHEELLARK 700
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
3-219 |
2.33e-41 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 150.29 E-value: 2.33e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF-KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGYL 76
Cdd:COG4988 337 IELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPAswrrqIAWV 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHwMTARETLTfMG-------------QLSGLkkEELSKSIPKILE-KVGLRGeenskvGTFSGGMKQRLGIAQ 142
Cdd:COG4988 417 PQNPYLFA-GTIRENLR-LGrpdasdeeleaalEAAGL--DEFVAALPDGLDtPLGEGG------RGLSGGQAQRLALAR 486
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 143 ALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRN 219
Cdd:COG4988 487 ALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILITHRLALLAQ-ADRILVLDDGRIVEQGTHEELLAKN 562
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-297 |
2.59e-41 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 145.62 E-value: 2.59e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKI---------------------AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLN 62
Cdd:COG4586 3 EVENLSKTYRVYEkepglkgalkglfrreyreveAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 63 GIKISkmKREIGYLPQYPNFF------HW-MTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMK 135
Cdd:COG4586 83 GYVPF--KRRKEFARRIGVVFgqrsqlWWdLPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 136 QRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTIT 213
Cdd:COG4586 161 MRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYnrERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGSLE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 214 ELLQRNSENKLIIEITAKDqkwIDVVKKLPYVKDVEVIGLKVKVKVESIEVNKNLLlqNALEHKVDIIKFEVSNDTLEEI 293
Cdd:COG4586 241 ELKERFGPYKTIVLELAEP---VPPLELPRGGEVIEREGNRVRLEVDPRESLAEVL--ARLLARYPVRDLTIEEPPIEEV 315
|
....
gi 1261024142 294 FLKL 297
Cdd:COG4586 316 IRRI 319
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
18-156 |
2.65e-41 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 140.09 E-value: 2.65e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 18 VNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM-----KREIGYLPQYPNFFHWMTARETL 92
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDerkslRKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 93 TFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVG----TFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:pfam00005 81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEP 148
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
3-217 |
3.76e-41 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 142.19 E-value: 3.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM------KREIGYL 76
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLppheraRAGIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTfMGqLSGLKKEELSKSIPKILEKV-GLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:cd03224 81 PEGRRIFPELTVEENLL-LG-AYARRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDE 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 156 PVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:cd03224 159 PSEGLAPKIVEEIFEAIRELRDEgVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLA 221
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
1-208 |
1.64e-40 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 144.13 E-value: 1.64e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG----IKISKMKREIGYL 76
Cdd:COG1118 1 MSIEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGrdlfTNLPPRERRVGFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFmgqlsGLKKEELSKS-----IPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLI 151
Cdd:COG1118 81 FQHYALFPHMTVAENIAF-----GLRVRPPSKAeirarVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 152 VMDEPVSALD----PIGRREVLNLIEEIKkdTTILLSTHILSDAEEICERFVIIKDGtKIE 208
Cdd:COG1118 156 LLDEPFGALDakvrKELRRWLRRLHDELG--GTTVFVTHDQEEALELADRVVVMNQG-RIE 213
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
3-204 |
2.52e-40 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 140.51 E-value: 2.52e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF-KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGI--------KISKMKREI 73
Cdd:TIGR02315 2 LEVENLSKVYpNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTditklrgkKLRKLRRRI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 GYLPQYPNFFHWMTARETL--------TFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALL 145
Cdd:TIGR02315 82 GMIFQHYNLIERLTVLENVlhgrlgykPTWRSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARALA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 146 HKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:TIGR02315 162 QQPDLILADEPIASLDPKTSKQVMDYLKRInkEDGITVIINLHQVDLAKKYADRIVGLKAG 222
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
3-225 |
5.66e-39 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 142.85 E-value: 5.66e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK------MKREIGYL 76
Cdd:COG1129 5 LEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFrsprdaQAAGIAII 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLtFMGQLSG----LKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIV 152
Cdd:COG1129 85 HQELNLVPNLSVAENI-FLGREPRrgglIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDARVLI 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 153 MDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELlqrnSENKLI 225
Cdd:COG1129 164 LDEPTASLTEREVERLFRIIRRLKAQgVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAEL----TEDELV 233
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
3-224 |
7.37e-39 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 136.76 E-value: 7.37e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFkGKIAV-NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-------KMKREIG 74
Cdd:PRK09493 2 IEFKNVSKHF-GPTQVlHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpkvderLIRQEAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHWMTARETLTFmG--QLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIV 152
Cdd:PRK09493 81 MVFQQFYLFPHLTALENVMF-GplRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLML 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 153 MDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSENKL 224
Cdd:PRK09493 160 FDEPTSALDPELRHEVLKVMQDLAEEgMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRL 232
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
3-221 |
1.42e-38 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 136.79 E-value: 1.42e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIK------ISKMKREIG 74
Cdd:TIGR04520 1 IEVENVSFSYPEseKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDtldeenLWEIRKKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:TIGR04520 81 MVFQNPdNQFVGATVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIIL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRNSE 221
Cdd:TIGR04520 161 DEATSMLDPKGRKEVLETIRKLNKEEgiTVISITHDMEEAVL-ADRVIVMNKGKIVAEGTPREIFSQVEL 229
|
|
| proV |
TIGR01186 |
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ... |
10-231 |
1.93e-38 |
|
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 138.83 E-value: 1.93e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 10 KSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---------KREIGYLPQYP 80
Cdd:TIGR01186 1 KKTGGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQspvelrevrRKKIGMVFQQF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 81 NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSAL 160
Cdd:TIGR01186 81 ALFPHMTILQNTSLGPELLGWPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSAL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 161 DPIGRREvlnLIEEIKK-----DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLqRNSENKLIIEITAK 231
Cdd:TIGR01186 161 DPLIRDS---MQDELKKlqatlQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEIL-RNPANEYVEEFIGK 232
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
3-208 |
3.48e-38 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 137.90 E-value: 3.48e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQ- 78
Cdd:COG3839 4 LELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLppkDRNIAMVFQs 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 ---YPNffhwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:COG3839 84 yalYPH----MTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDE 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 156 PVSALDPIGRREvlnLIEEIKK-----DTTILLSTHilsDAEE---ICERFVIIKDGtKIE 208
Cdd:COG3839 160 PLSNLDAKLRVE---MRAEIKRlhrrlGTTTIYVTH---DQVEamtLADRIAVMNDG-RIQ 213
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
1-208 |
3.93e-38 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 134.77 E-value: 3.93e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLP 77
Cdd:cd03296 1 MSIEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVpvqERNVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPNFFHWMTARETLTFmgqlsGLK---------KEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKP 148
Cdd:cd03296 81 QHYALFRHMTVFDNVAF-----GLRvkprserppEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEP 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 149 SLIVMDEPVSALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFVIIKDGtKIE 208
Cdd:cd03296 156 KVLLLDEPFGALDAKVRKELRRWLRRLHDELhvTTVFVTHDQEEALEVADRVVVMNKG-RIE 216
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
3-223 |
2.05e-37 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 132.84 E-value: 2.05e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKgKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQY 79
Cdd:cd03299 1 LKVENLSKDWK-EFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLppeKRDISYVPQN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 80 PNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:cd03299 80 YALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 160 LDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSENK 223
Cdd:cd03299 160 LDVRTKEKLREELKKIRKefGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEF 225
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
3-204 |
4.89e-37 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 131.38 E-value: 4.89e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK--------REI 73
Cdd:cd03292 1 IEFINVTKTYPNGTaALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRgraipylrRKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 GYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEI-KKDTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:cd03292 161 DEPTGNLDPDTTWEIMNLLKKInKAGTTVVVATHAKELVDTTRHRVIALERG 212
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
3-208 |
3.11e-36 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 129.66 E-value: 3.11e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQ- 78
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLpphKRPVNTVFQn 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:cd03300 81 YALFPH-LTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLG 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 159 ALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGtKIE 208
Cdd:cd03300 160 ALDLKLRKDMQLELKRLQKElgITFVFVTHDQEEALTMSDRIAVMNKG-KIQ 210
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
15-218 |
3.12e-36 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 131.03 E-value: 3.12e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 15 KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS--------KMKREIGYLPQYP--NFFH 84
Cdd:TIGR04521 18 KKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITakkkkklkDLRKKVGLVFQFPehQLFE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 85 wMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLrGEENSKVGTF--SGGMKQRLGIAQALLHKPSLIVMDEPVSALDP 162
Cdd:TIGR04521 98 -ETVYKDIAFGPKNLGLSEEEAEERVKEALELVGL-DEEYLERSPFelSGGQMRRVAIAGVLAMEPEVLILDEPTAGLDP 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 163 IGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:TIGR04521 176 KGRKEILDLFKRLhkEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSD 233
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
3-207 |
5.75e-36 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 126.77 E-value: 5.75e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISkmkreigylpqypnf 82
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVS--------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 FHwmTARETLtfmgqlsglkkeelsksipkilekvglrgeeNSKVGT---FSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:cd03216 66 FA--SPRDAR-------------------------------RAGIAMvyqLSVGERQMVEIARALARNARLLILDEPTAA 112
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1261024142 160 LDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKI 207
Cdd:cd03216 113 LTPAEVERLFKVIRRLRAQgVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
12-209 |
8.67e-36 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 128.60 E-value: 8.67e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 12 FKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGI----KISKMKREIGYLPQYPNFFHW-M 86
Cdd:cd03267 31 YREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLvpwkRRKKFLRRIGVVFGQKTQLWWdL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 87 TARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRR 166
Cdd:cd03267 111 PVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQE 190
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1261024142 167 EVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIED 209
Cdd:cd03267 191 NIRNFLKEYNRErgTTVLLTSHYMKDIEALARRVLVIDKGRLLYD 235
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
3-216 |
1.29e-35 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 129.15 E-value: 1.29e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF--------KGKIAV-NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK--- 70
Cdd:TIGR02769 3 LEVRDVTHTYrtgglfgaKQRAPVlTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDrkq 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 -----REIGYLPQ--YPNFFHWMTARETLTF-MGQLSGLKKEELSKSIPKILEKVGLRGEENSKV-GTFSGGMKQRLGIA 141
Cdd:TIGR02769 83 rrafrRDVQLVFQdsPSAVNPRMTVRQIIGEpLRHLTSLDESEQKARIAELLDMVGLRSEDADKLpRQLSGGQLQRINIA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 142 QALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:TIGR02769 163 RALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAfgTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQLL 239
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
3-216 |
1.46e-35 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 127.79 E-value: 1.46e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTkSFKGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE------IGY 75
Cdd:COG0410 4 LEVENLH-AGYGGIhVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHriarlgIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTARETLTfMGQLSGLKKEELSKSIPKILE---KVGLRgeENSKVGTFSGGMKQRLGIAQALLHKPSLIV 152
Cdd:COG0410 83 VPEGRRIFPSLTVEENLL-LGAYARRDRAEVRADLERVYElfpRLKER--RRQRAGTLSGGEQQMLAIGRALMSRPKLLL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 153 MDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:COG0410 160 LDEPSLGLAPLIVEEIFEIIRRLNREgVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELL 224
|
|
| ABC_ATP_SaoA |
NF040729 |
ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC ... |
2-227 |
2.30e-35 |
|
ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC transporter in which both the permease subunit SaoP, and the substrate-binding protein SaoB, are nearly always selenoproteins that were unrecognized as such until recently (2022). The SAO system is found in Clostridium difficile and various other anaerobic heterotrophs.
Pssm-ID: 468693 [Multi-domain] Cd Length: 248 Bit Score: 127.94 E-value: 2.30e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIAVN----NFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYLP 77
Cdd:NF040729 1 KLKIQNISKTFINNKKENevlkDISFDVEEGEFVSLLGPSGCGKTTLLTIIAGFQNATSGEILVNGNEVTKPGPDRGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPV 157
Cdd:NF040729 81 QNYALFPWMTVKENIEYPMKQQKMPKQEREKRLNELLEMAQLTGKENLYPHQISGGMKQRTAVIRALACKPEVLLMDEPL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 158 SALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVII--KDGTKIEDTTITELLQRNSENKLIIE 227
Cdd:NF040729 161 GAVDFQMRQILQEELESIwlKDKTTVLMVTHDVDEAVYLSDRVIVMsrDKGKILEDLKIDLPRPRNRESEKYLE 234
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
3-204 |
3.24e-35 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 126.60 E-value: 3.24e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQ- 78
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLppkDRDIAMVFQn 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 ---YPNffhwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:cd03301 81 yalYPH----MTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 156 PVSALDPIGRREVLNlieEIKK-----DTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:cd03301 157 PLSNLDAKLRVQMRA---ELKRlqqrlGTTTIYVTHDQVEAMTMADRIAVMNDG 207
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
3-218 |
3.86e-35 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 127.12 E-value: 3.86e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK----------------------GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVL 60
Cdd:COG1134 5 IEVENVSKSYRlyhepsrslkelllrrrrtrreEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 61 LNGiKISKMkreI----GYLPQypnffhwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQ 136
Cdd:COG1134 85 VNG-RVSAL---LelgaGFHPE-------LTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSSGMRA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 137 RLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:COG1134 154 RLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESgRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEV 233
|
...
gi 1261024142 216 LQR 218
Cdd:COG1134 234 IAA 236
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
4-214 |
1.06e-34 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 128.38 E-value: 1.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGK----IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK--------R 71
Cdd:PRK11153 3 ELKNISKVFPQGgrtiHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSekelrkarR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 72 EIGYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLI 151
Cdd:PRK11153 83 QIGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 152 VMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITE 214
Cdd:PRK11153 163 LCDEATSALDPATTRSILELLKDINRElgLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSE 227
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-193 |
1.60e-34 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 126.13 E-value: 1.60e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKG----KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYL 76
Cdd:COG4525 2 SMLTVRHVSVRYPGggqpQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGADRGVV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:COG4525 82 FQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEP 161
|
170 180 190
....*....|....*....|....*....|....*....
gi 1261024142 157 VSALDPIGRREVLNLIEEIKKDT--TILLSTHilsDAEE 193
Cdd:COG4525 162 FGALDALTREQMQELLLDVWQRTgkGVFLITH---SVEE 197
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
21-205 |
1.76e-34 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 124.53 E-value: 1.76e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 21 FSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQYPNFFHWMTArETLTFMGQ 97
Cdd:cd03298 17 FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAppaDRPVSMLFQENNLFAHLTV-EQNVGLGL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 98 LSGLK-KEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIK 176
Cdd:cd03298 96 SPGLKlTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDLH 175
|
170 180 190
....*....|....*....|....*....|.
gi 1261024142 177 KDT--TILLSTHILSDAEEICERFVIIKDGT 205
Cdd:cd03298 176 AETkmTVLMVTHQPEDAKRLAQRVVFLDNGR 206
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
3-222 |
5.51e-34 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 124.04 E-value: 5.51e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVL------LNGIKISKMKREIGY- 75
Cdd:COG1119 4 LELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVrlfgerRGGEDVWELRKRIGLv 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 ---LPQYpnFFHWMTARETLtfmgqLSGL----------KKEELSKSIpKILEKVGLRGEENSKVGTFSGGMKQRLGIAQ 142
Cdd:COG1119 84 spaLQLR--FPRDETVLDVV-----LSGFfdsiglyrepTDEQRERAR-ELLELLGLAHLADRPFGTLSQGEQRRVLIAR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 143 ALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHilsDAEEI--C-ERFVIIKDGTKIEDTTITELLq 217
Cdd:COG1119 156 ALVKDPELLILDEPTAGLDLGARELLLALLDKLaaEGAPTLVLVTH---HVEEIppGiTHVLLLKDGRVVAAGPKEEVL- 231
|
....*
gi 1261024142 218 rNSEN 222
Cdd:COG1119 232 -TSEN 235
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
2-204 |
9.86e-34 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 126.76 E-value: 9.86e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSF------------KGK------------IAVNNFSMELQSGE-CVgLIGPNGAGKSTLIKVISDIINPNA 56
Cdd:COG4175 3 KIEVRNLYKIFgkrperalklldQGKskdeilektgqtVGVNDASFDVEEGEiFV-IMGLSGSGKSTLVRCLNRLIEPTA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 57 GEVLLNGIKISKMK----REI------------GYLPqypnffhWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLR 120
Cdd:COG4175 82 GEVLIDGEDITKLSkkelRELrrkkmsmvfqhfALLP-------HRTVLENVAFGLEIQGVPKAERRERAREALELVGLA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 121 GEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRR----EVLNLIEEIKKdtTILLSTHILSDAEEICE 196
Cdd:COG4175 155 GWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPLIRRemqdELLELQAKLKK--TIVFITHDLDEALRLGD 232
|
....*...
gi 1261024142 197 RFVIIKDG 204
Cdd:COG4175 233 RIAIMKDG 240
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
3-208 |
1.05e-33 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 123.71 E-value: 1.05e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-------------KM 69
Cdd:PRK11264 4 IEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDtarslsqqkglirQL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYLPQYPNFFHWMTARETLtFMG--QLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHK 147
Cdd:PRK11264 84 RQHVGFVFQNFNLFPHRTVLENI-IEGpvIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMR 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 148 PSLIVMDEPVSALDPIGRREVLNLIEEIKKDT-TILLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:PRK11264 163 PEVILFDEPTSALDPELVGEVLNTIRQLAQEKrTMVIVTHEMSFARDVADRAIFMDQGRIVE 224
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
5-204 |
1.32e-33 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 130.52 E-value: 1.32e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFK--GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK----MKREIGYLPQ 78
Cdd:TIGR01257 931 VKNLVKIFEpsGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETnldaVRQSLGMCPQ 1010
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:TIGR01257 1011 HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTS 1090
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1261024142 159 ALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:TIGR01257 1091 GVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQG 1136
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
4-205 |
1.47e-33 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 121.98 E-value: 1.47e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE--IGYLPQYP 80
Cdd:cd03226 1 RIENISFSYKKGTeILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKERRksIGYVMQDV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 81 NF-FHWMTARETLTFMGQLSGLKKEElsksIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:cd03226 81 DYqLFTDSVREELLLGLKELDAGNEQ----AETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSG 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1261024142 160 LDPIGRREVLNLIEEIKK-DTTILLSTHILSDAEEICERFVIIKDGT 205
Cdd:cd03226 157 LDYKNMERVGELIRELAAqGKAVIVITHDYEFLAKVCDRVLLLANGA 203
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
3-219 |
4.22e-33 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 127.59 E-value: 4.22e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVtkSF---KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IG 74
Cdd:COG1132 340 IEFENV--SFsypGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLEslrrqIG 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHwMTARETLTFmgqlsG------------LKKEELSKSIPKiLEK-----VGLRGeenskvGTFSGGMKQR 137
Cdd:COG1132 418 VVPQDTFLFS-GTIRENIRY-----GrpdatdeeveeaAKAAQAHEFIEA-LPDgydtvVGERG------VNLSGGQRQR 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 138 LGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEIcerfVIIKDGTKIEDTTITE 214
Cdd:COG1132 485 IAIARALLKDPPILILDEATSALDTETEALIQEALERLMKGRTTIVIAHRLStirNADRI----LVLDDGRIVEQGTHEE 560
|
....*
gi 1261024142 215 LLQRN 219
Cdd:COG1132 561 LLARG 565
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
2-209 |
5.17e-33 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 120.77 E-value: 5.17e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM-----KREIG 74
Cdd:cd03245 2 RIEFRNVSFSYPNqeIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLdpadlRRNIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFhWMTARETLTFMGQ------------LSGLkkEELSKSIPKILE-KVGLRGEEnskvgtFSGGMKQRLGIA 141
Cdd:cd03245 82 YVPQDVTLF-YGTLRDNITLGAPladderilraaeLAGV--TDFVNKHPNGLDlQIGERGRG------LSGGQRQAVALA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 142 QALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSdAEEICERFVIIKDGTKIED 209
Cdd:cd03245 153 RALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTLIIITHRPS-LLDLVDRIIVMDSGRIVAD 219
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-215 |
9.72e-33 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 125.91 E-value: 9.72e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG--IKISK----MKREIG 74
Cdd:COG3845 4 PALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGkpVRIRSprdaIALGIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHWMTARETLTfMGQLSG----LKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSL 150
Cdd:COG3845 84 MVHQHFMLVPNLTVAENIV-LGLEPTkggrLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARI 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 151 IVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKI-----EDTTITEL 215
Cdd:COG3845 163 LILDEPTAVLTPQEADELFEILRRLAAEgKSIIFITHKLREVMAIADRVTVLRRGKVVgtvdtAETSEEEL 233
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
21-230 |
1.58e-32 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 120.07 E-value: 1.58e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 21 FSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGI---KISKMKREIGYLPQYPNFFHWMTARETLTfMGQ 97
Cdd:PRK10771 18 FDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQdhtTTPPSRRPVSMLFQENNLFSHLTVAQNIG-LGL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 98 LSGLK-KEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI- 175
Cdd:PRK10771 97 NPGLKlNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVc 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 176 -KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSENKLIIEITA 230
Cdd:PRK10771 177 qERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLSGKASASALLGIKS 232
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
3-193 |
2.37e-32 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 120.19 E-value: 2.37e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYLPQYPNF 82
Cdd:PRK11248 2 LQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAERGVVFQNEGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 FHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDP 162
Cdd:PRK11248 82 LPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDA 161
|
170 180 190
....*....|....*....|....*....|...
gi 1261024142 163 IGRREVLNLIEEIKKDT--TILLSTHilsDAEE 193
Cdd:PRK11248 162 FTREQMQTLLLKLWQETgkQVLLITH---DIEE 191
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
3-209 |
3.45e-32 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 117.41 E-value: 3.45e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE----IGYL 76
Cdd:cd03247 1 LSINNVSFSYPEqeQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKAlsslISVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHwmtaretltfmgqlsglkkeelsksiPKILEKVGLRgeenskvgtFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:cd03247 81 NQRPYLFD--------------------------TTLRNNLGRR---------FSGGERQRLALARILLQDAPIVLLDEP 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 157 VSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEIcERFVIIKDGTKIED 209
Cdd:cd03247 126 TVGLDPITERQLLSLIFEVLKDKTLIWITHHLTGIEHM-DKILFLENGKIIMQ 177
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
3-204 |
3.73e-32 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 117.32 E-value: 3.73e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGY 75
Cdd:cd03246 1 LEVENVSFRYPGaePPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNelgdhVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQypnffhwmtarETLTFMGQLSglkkeelsksipkilekvglrgeENskvgTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:cd03246 81 LPQ-----------DDELFSGSIA-----------------------EN----ILSGGQRQRLGLARALYGNPRILVLDE 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1261024142 156 PVSALDPIGRREVLNLIEEIKK-DTTILLSTHILSdAEEICERFVIIKDG 204
Cdd:cd03246 123 PNSHLDVEGERALNQAIAALKAaGATRIVIAHRPE-TLASADRILVLEDG 171
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
2-221 |
3.75e-32 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 120.12 E-value: 3.75e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIG 74
Cdd:PRK13635 5 IIRVEHISFRYPDaaTYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEetvwdVRRQVG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:PRK13635 85 MVFQNPdNQFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIIL 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIK--KDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRNSE 221
Cdd:PRK13635 165 DEATSMLDPRGRREVLETVRQLKeqKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIFKSGHM 233
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
3-217 |
3.82e-32 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 119.23 E-value: 3.82e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS------KMKREIGYL 76
Cdd:PRK10895 4 LTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISllplhaRARRGIGYL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQL-SGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:PRK10895 84 PQEASIFRRLSVYDNLMAVLQIrDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDE 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 156 PVSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:PRK10895 164 PFAGVDPISVIDIKRIIEHLRdSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQ 226
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
1-214 |
4.32e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 120.15 E-value: 4.32e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVT-----KSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGI-------KISK 68
Cdd:PRK13637 1 MSIKIENLThiymeGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVditdkkvKLSD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 69 MKREIGYLPQYPNF-FHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTF--SGGMKQRLGIAQALL 145
Cdd:PRK13637 81 IRKKVGLVFQYPEYqLFEETIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLDYEDYKDKSPFelSGGQKRRVAIAGVVA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 146 HKPSLIVMDEPVSALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITE 214
Cdd:PRK13637 161 MEPKILILDEPTAGLDPKGRDEILNKIKELHKeyNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPRE 231
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
3-209 |
7.27e-32 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 118.02 E-value: 7.27e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF----------------------KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVL 60
Cdd:cd03220 1 IELENVSKSYptykggssslkklgilgrkgevGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 61 LNGiKISKMKRE-IGYLPQypnffhwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLG 139
Cdd:cd03220 81 VRG-RVSSLLGLgGGFNPE-------LTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 140 IAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEE-IKKDTTILLSTHILSDAEEICERFVIIKDGTKIED 209
Cdd:cd03220 153 FAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRElLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFD 223
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
22-218 |
1.28e-31 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 120.60 E-value: 1.28e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 22 SMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG---------IKISKMKREIGYLPQYPNFFHWMTARETL 92
Cdd:TIGR02142 17 DFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGrtlfdsrkgIFLPPEKRRIGYVFQEARLFPHLSVRGNL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 93 TFmgqlsGLKK---EELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVL 169
Cdd:TIGR02142 97 RY-----GMKRarpSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEIL 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 170 NLIEEIKKDTTI--LLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:TIGR02142 172 PYLERLHAEFGIpiLYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWAS 222
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
3-204 |
1.59e-31 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 120.71 E-value: 1.59e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQY 79
Cdd:PRK11607 20 LEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVppyQRPINMMFQS 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 80 PNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:PRK11607 100 YALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGA 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1261024142 160 LDPIGRR----EVLNLIEEIkkDTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:PRK11607 180 LDKKLRDrmqlEVVDILERV--GVTCVMVTHDQEEAMTMAGRIAIMNRG 226
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
1-227 |
2.00e-31 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 120.19 E-value: 2.00e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLP 77
Cdd:PRK10851 1 MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLharDRKVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPNFFHWMTARETLTFmgqlsGLK---------KEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKP 148
Cdd:PRK10851 81 QHYALFRHMTVFDNIAF-----GLTvlprrerpnAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 149 SLIVMDEPVSALDPIGRRE----VLNLIEEIKkdTTILLSTHILSDAEEICERFVIIKDGtKIEDTTITELLQRNSENKL 224
Cdd:PRK10851 156 QILLLDEPFGALDAQVRKElrrwLRQLHEELK--FTSVFVTHDQEEAMEVADRVVVMSQG-NIEQAGTPDQVWREPATRF 232
|
...
gi 1261024142 225 IIE 227
Cdd:PRK10851 233 VLE 235
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
3-208 |
3.44e-31 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 121.71 E-value: 3.44e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLnGIKIskmkrEIGYLPQYPNF 82
Cdd:COG0488 316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV-----KIGYFDQHQEE 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 FHwmtarETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEE-NSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:COG0488 390 LD-----PDKTVLDELRDGAPGGTEQEVRGYLGRFLFSGDDaFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLD 464
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 162 PigrrEVLNLIEEIKKDT--TILLSTHilsD---AEEICERFVIIKDGTKIE 208
Cdd:COG0488 465 I----ETLEALEEALDDFpgTVLLVSH---DryfLDRVATRILEFEDGGVRE 509
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
3-205 |
3.93e-31 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 123.20 E-value: 3.93e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKI--AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG----IKISKMKREIGYL 76
Cdd:TIGR01257 1938 LRLNELTKVYSGTSspAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGksilTNISDVHQNMGYC 2017
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:TIGR01257 2018 PQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEP 2097
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1261024142 157 VSALDPIGRREVLNLIEE-IKKDTTILLSTHILSDAEEICERFVIIKDGT 205
Cdd:TIGR01257 2098 TTGMDPQARRMLWNTIVSiIREGRAVVLTSHSMEECEALCTRLAIMVKGA 2147
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-186 |
4.73e-31 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 116.67 E-value: 4.73e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVI---SDIInPNA---GEVLLNGIKISKMK----- 70
Cdd:COG1117 11 KIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmNDLI-PGArveGEILLDGEDIYDPDvdvve 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 --REIGYLPQYPNFFHwMTARETLTFMGQLSGLK-KEELSKSIPKILEKVGLrGEE-----NSKVGTFSGGMKQRLGIAQ 142
Cdd:COG1117 90 lrRRVGMVFQKPNPFP-KSIYDNVAYGLRLHGIKsKSELDEIVEESLRKAAL-WDEvkdrlKKSALGLSGGQQQRLCIAR 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1261024142 143 ALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTH 186
Cdd:COG1117 168 ALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIVTH 211
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
3-215 |
8.07e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 116.72 E-value: 8.07e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF-KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-------KMKREIG 74
Cdd:PRK13639 2 LETRDLKYSYpDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKydkksllEVRKTVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:PRK13639 82 IVFQNPdDQLFAPTVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEI-KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:PRK13639 162 DEPTSGLDPMGASQIMKLLYDLnKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEV 224
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
3-208 |
1.19e-30 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 115.64 E-value: 1.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDI--INPN---AGEVLLNGIKI-------SKMK 70
Cdd:PRK14239 6 LQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndLNPEvtiTGSIVYNGHNIysprtdtVDLR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 REIGYLPQYPNFFHwMTARETLTFMGQLSGLK-KEELSKSIPKILEKVGLRGE-----ENSKVGtFSGGMKQRLGIAQAL 144
Cdd:PRK14239 86 KEIGMVFQQPNPFP-MSIYENVVYGLRLKGIKdKQVLDEAVEKSLKGASIWDEvkdrlHDSALG-LSGGQQQRVCIARVL 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 145 LHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:PRK14239 164 ATSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIE 227
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
3-197 |
1.45e-30 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 117.14 E-value: 1.45e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF--KGKI---------AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK- 70
Cdd:COG4608 8 LEVRDLKKHFpvRGGLfgrtvgvvkAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSg 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 -------REIGYLPQ--Y----PNffhwMTARETLTFMGQLSGLK-KEELSKSIPKILEKVGLRGE-------Enskvgt 129
Cdd:COG4608 88 relrplrRRMQMVFQdpYaslnPR----MTVGDIIAEPLRIHGLAsKAERRERVAELLELVGLRPEhadryphE------ 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 130 FSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICER 197
Cdd:COG4608 158 FSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDElgLTYLFISHDLSVVRHISDR 227
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
3-193 |
1.53e-30 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 114.12 E-value: 1.53e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNA---GEVLLNGIKISKM---KREIGYL 76
Cdd:COG4136 2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAFsasGEVLLNGRRLTALpaeQRRIGIL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFmGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:COG4136 82 FQDDLLFPHLSVGENLAF-ALPPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEP 160
|
170 180 190
....*....|....*....|....*....|....*....
gi 1261024142 157 VSALDPIGRREVLNLI-EEIKKDTTI-LLSTHILSDAEE 193
Cdd:COG4136 161 FSKLDAALRAQFREFVfEQIRQRGIPaLLVTHDEEDAPA 199
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
5-156 |
2.98e-30 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 119.01 E-value: 2.98e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLL-NGIKiskmkreIGYLPQYPNFF 83
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIpKGLR-------IGYLPQEPPLD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 84 HWMTARETLtFMG--QLSGLKKE--ELSKSIP-----------------------------KILEKVGLRGEE-NSKVGT 129
Cdd:COG0488 74 DDLTVLDTV-LDGdaELRALEAEleELEAKLAepdedlerlaelqeefealggweaearaeEILSGLGFPEEDlDRPVSE 152
|
170 180
....*....|....*....|....*..
gi 1261024142 130 FSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:COG0488 153 LSGGWRRRVALARALLSEPDLLLLDEP 179
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
3-194 |
7.95e-30 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 112.07 E-value: 7.95e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK----REIGYLPQ 78
Cdd:TIGR01189 1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRdephENILYLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEELSKSipkiLEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:TIGR01189 81 LPGLKPELSALENLHFWAAIHGGAQRTIEDA----LAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTT 156
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1261024142 159 ALDPIGRREVLNLIEE-IKKDTTILLSTHI---LSDAEEI 194
Cdd:TIGR01189 157 ALDKAGVALLAGLLRAhLARGGIVLLTTHQdlgLVEAREL 196
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
4-219 |
8.00e-30 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 113.02 E-value: 8.00e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSF---KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM-----KREIGY 75
Cdd:cd03249 2 EFKNVSFRYpsrPDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLnlrwlRSQIGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHwMTARETLTFmGQLSG--------LKKEELSKSIPKILEK----VGLRGeenskvGTFSGGMKQRLGIAQA 143
Cdd:cd03249 82 VSQEPVLFD-GTIAENIRY-GKPDAtdeeveeaAKKANIHDFIMSLPDGydtlVGERG------SQLSGGQKQRIAIARA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEICerfvIIKDGTKIEDTTITELLQRN 219
Cdd:cd03249 154 LLRNPKILLLDEATSALDAESEKLVQEALDRAMKGRTTIVIAHRLStirNADLIA----VLQNGQVVEQGTHDELMAQK 228
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
3-221 |
9.86e-30 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 113.16 E-value: 9.86e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGikiskmkREIGYLP----- 77
Cdd:PRK11300 6 LSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRG-------QHIEGLPghqia 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 --------QYPNFFHWMTARETLTF-------MGQLSGLKK---------EELSKSIpKILEKVGLRGEENSKVGTFSGG 133
Cdd:PRK11300 79 rmgvvrtfQHVRLFREMTVIENLLVaqhqqlkTGLFSGLLKtpafrraesEALDRAA-TWLERVGLLEHANRQAGNLAYG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 134 MKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTT 211
Cdd:PRK11300 158 QQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEhnVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGT 237
|
250
....*....|
gi 1261024142 212 ITELlqRNSE 221
Cdd:PRK11300 238 PEEI--RNNP 245
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
3-204 |
1.62e-29 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 112.85 E-value: 1.62e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYLPQYPNF 82
Cdd:PRK11247 13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEAREDTRLMFQDARL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 FHWMTARETLTFmgqlsGLKKEELSKSIpKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDP 162
Cdd:PRK11247 93 LPWKKVIDNVGL-----GLKGQWRDAAL-QALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDA 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1261024142 163 IGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:PRK11247 167 LTRIEMQDLIESLwqQHGFTVLLVTHDVSEAVAMADRVLLIEEG 210
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
3-182 |
1.74e-29 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 112.52 E-value: 1.74e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK------REIGYL 76
Cdd:COG4674 11 LYVEDLTVSFDGFKALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGLDeheiarLGIGRK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETL------------TFMGQLSGLKKEElsksIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQAL 144
Cdd:COG4674 91 FQKPTVFEELTVFENLelalkgdrgvfaSLFARLTAEERDR----IEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLL 166
|
170 180 190
....*....|....*....|....*....|....*...
gi 1261024142 145 LHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTIL 182
Cdd:COG4674 167 AQDPKLLLLDEPVAGMTDAETERTAELLKSLAGKHSVV 204
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
1-218 |
1.84e-29 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 114.81 E-value: 1.84e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRnVTKSFKG-KIAVNnfsMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG---------IKISKMK 70
Cdd:COG4148 1 MMLEVD-FRLRRGGfTLDVD---FTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGevlqdsargIFLPPHR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 REIGYLPQYPNFFHWMTARETLTFmgqlsGLKKEELSK---SIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHK 147
Cdd:COG4148 77 RRIGYVFQEARLFPHLSVRGNLLY-----GRKRAPRAErriSFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSS 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 148 PSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTI--LLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:COG4148 152 PRLLLMDEPLAALDLARKAEILPYLERLRDELDIpiLYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSR 224
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1-217 |
2.07e-29 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 112.56 E-value: 2.07e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGY 75
Cdd:PRK13548 1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAelarrRAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPnffhwmtareTLTF---------MGQLS-GLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALL 145
Cdd:PRK13548 81 LPQHS----------SLSFpftveevvaMGRAPhGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 146 ------HKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:PRK13548 151 qlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHErgLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVLT 230
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
3-221 |
3.87e-29 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 113.66 E-value: 3.87e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG---IKISKMKREIGYLPQ- 78
Cdd:PRK11432 7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGedvTHRSIQQRDICMVFQs 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:PRK11432 87 YALFPH-MSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLS 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 159 ALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR-NSE 221
Cdd:PRK11432 166 NLDANLRRSMREKIRELQQqfNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQpASR 231
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
2-205 |
6.89e-29 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 115.62 E-value: 6.89e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IG 74
Cdd:COG4618 330 RLSVENLTVVPPGskRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREelgrhIG 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHwMTARETLTFMG-----------QLSGLKkeELSKSIPKILE-KVGLRGeenskvGTFSGGMKQRLGIAQ 142
Cdd:COG4618 410 YLPQDVELFD-GTIAENIARFGdadpekvvaaaKLAGVH--EMILRLPDGYDtRIGEGG------ARLSGGQRQRIGLAR 480
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 143 ALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTH---ILSdaeeICERFVIIKDGT 205
Cdd:COG4618 481 ALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKARgATVVVITHrpsLLA----AVDKLLVLRDGR 543
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
3-193 |
7.47e-29 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 115.46 E-value: 7.47e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGK-IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYL 76
Cdd:TIGR02857 322 LEFSGVSVAYPGRrPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADadswrDQIAWV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHwMTARETLTF------------MGQLSGLkkEELSKSIPKILE-KVGLRGEEnskvgtFSGGMKQRLGIAQA 143
Cdd:TIGR02857 402 PQHPFLFA-GTIAENIRLarpdasdaeireALERAGL--DEFVAALPQGLDtPIGEGGAG------LSGGQAQRLALARA 472
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEE 193
Cdd:TIGR02857 473 FLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLVTHRLALAAL 522
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
11-194 |
9.56e-29 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 108.86 E-value: 9.56e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 11 SFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGikiskmKREIGYLPQ-------YPnff 83
Cdd:NF040873 1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAG------GARVAYVPQrsevpdsLP--- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 84 hwMTARETLTfMGQ-----LSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:NF040873 72 --LTVRDLVA-MGRwarrgLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTT 148
|
170 180 190
....*....|....*....|....*....|....*..
gi 1261024142 159 ALDPIGRREVLNLIEEIKKD-TTILLSTHilsDAEEI 194
Cdd:NF040873 149 GLDAESRERIIALLAEEHARgATVVVVTH---DLELV 182
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
18-204 |
9.93e-29 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 109.86 E-value: 9.93e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 18 VNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYLPQYPNFFHWMTARET--LTFM 95
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRMVVFQNYSLLPWLTVRENiaLAVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 96 GQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI 175
Cdd:TIGR01184 81 RVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELMQI 160
|
170 180 190
....*....|....*....|....*....|.
gi 1261024142 176 KKDT--TILLSTHILSDAEEICERFVIIKDG 204
Cdd:TIGR01184 161 WEEHrvTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
17-186 |
1.30e-28 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 108.28 E-value: 1.30e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-------KMKREIGYLPQYPN--FFHwMT 87
Cdd:TIGR01166 7 VLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLDysrkgllERRQRVGLVFQDPDdqLFA-AD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 88 ARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRRE 167
Cdd:TIGR01166 86 VDQDVAFGPLNLGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLDPAGREQ 165
|
170 180
....*....|....*....|
gi 1261024142 168 VLNLIEEIKKD-TTILLSTH 186
Cdd:TIGR01166 166 MLAILRRLRAEgMTVVISTH 185
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
13-225 |
1.46e-28 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 110.56 E-value: 1.46e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 13 KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK------REIGYLPQYP-NFFHW 85
Cdd:PRK13633 21 TEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEEnlwdirNKAGMVFQNPdNQIVA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 86 MTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGR 165
Cdd:PRK13633 101 TIVEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGR 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 166 REVLNLIEEIKKD--TTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRNSENKLI 225
Cdd:PRK13633 181 REVVNTIKELNKKygITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIFKEVEMMKKI 241
|
|
| nickel_nikD |
TIGR02770 |
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ... |
17-218 |
2.10e-28 |
|
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 109.00 E-value: 2.10e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNA----GEVLLNGIKISKMK---REIGYLPQYP----NFFHW 85
Cdd:TIGR02770 1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLtqtsGEILLDGRPLLPLSirgRHIATIMQNPrtafNPLFT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 86 MT--ARETLTFMGQLSGLKKEELSKSipkiLEKVGLR-GEENSKVGTF--SGGMKQRLGIAQALLHKPSLIVMDEPVSAL 160
Cdd:TIGR02770 81 MGnhAIETLRSLGKLSKQARALILEA----LEAVGLPdPEEVLKKYPFqlSGGMLQRVMIALALLLEPPFLIADEPTTDL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 161 DPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:TIGR02770 157 DVVNQARVLKLLRELRQLfgTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYN 216
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
3-205 |
2.99e-28 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 108.68 E-value: 2.99e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-----GKI--AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLN----GIKISKM-- 69
Cdd:COG4778 5 LEVENLSKTFTlhlqgGKRlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRhdggWVDLAQAsp 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 -------KREIGYLPQypnFFHWM---TARETLTFMGQLSGLKKEELSKSIPKILEKVGLRgEE--NSKVGTFSGGMKQR 137
Cdd:COG4778 85 reilalrRRTIGYVSQ---FLRVIprvSALDVVAEPLLERGVDREEARARARELLARLNLP-ERlwDLPPATFSGGEQQR 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 138 LGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGT 205
Cdd:COG4778 161 VNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARgTAIIGIFHDEEVREAVADRVVDVTPFS 229
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
3-208 |
5.25e-28 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 111.19 E-value: 5.25e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---KREIGYLPQ- 78
Cdd:PRK09452 15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVpaeNRHVNTVFQs 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:PRK09452 95 YALFPH-MTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLS 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 159 ALDPIGRREVLNLIEEIKKDT--TILLSTHilsDAEE---ICERFVIIKDGtKIE 208
Cdd:PRK09452 174 ALDYKLRKQMQNELKALQRKLgiTFVFVTH---DQEEaltMSDRIVVMRDG-RIE 224
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
3-220 |
6.79e-28 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 107.70 E-value: 6.79e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGYL 76
Cdd:cd03253 1 IEFENVTFAYDpGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREvtldsLRRAIGVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHwMTARETLTFmGQLSGLKKE--ELSKsIPKILEKV-GLRGEENSKVG----TFSGGMKQRLGIAQALLHKPS 149
Cdd:cd03253 81 PQDTVLFN-DTIGYNIRY-GRPDATDEEviEAAK-AAQIHDKImRFPDGYDTIVGerglKLSGGEKQRVAIARAILKNPP 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 150 LIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEIcerfVIIKDGTKIEDTTITELLQRNS 220
Cdd:cd03253 158 ILLLDEATSALDTHTEREIQAALRDVSKGRTTIVIAHRLStivNADKI----IVLKDGRIVERGTHEELLAKGG 227
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
3-224 |
7.96e-28 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 108.01 E-value: 7.96e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDII--NPNA---GEVLLNGIKIS-------KMK 70
Cdd:PRK14267 5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLelNEEArveGEVRLFGRNIYspdvdpiEVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 REIGYLPQYPNFFHWMTARETLTFMGQLSGL--KKEELSKSIPKILEKVGLRGEE----NSKVGTFSGGMKQRLGIAQAL 144
Cdd:PRK14267 85 REVGMVFQYPNPFPHLTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAALWDEVkdrlNDYPSNLSGGQRQRLVIARAL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 145 LHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQrNSENKL 224
Cdd:PRK14267 165 AMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFE-NPEHEL 243
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
2-219 |
8.18e-28 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 107.31 E-value: 8.18e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSF-KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGY 75
Cdd:cd03254 2 EIEFENVNFSYdEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKslrsmIGV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHwMTARETLTFMGQLSGLKKEELSKSIPKILEKV-----GLRGEENSKVGTFSGGMKQRLGIAQALLHKPSL 150
Cdd:cd03254 82 VLQDTFLFS-GTIMENIRLGRPNATDEEVIEAAKEAGAHDFImklpnGYDTVLGENGGNLSQGERQLLAIARAMLRDPKI 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 151 IVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEIcerfVIIKDGTKIEDTTITELLQRN 219
Cdd:cd03254 161 LILDEATSNIDTETEKLIQEALEKLMKGRTSIIIAHRLStikNADKI----LVLDDGKIIEEGTHDELLAKK 228
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
3-219 |
9.74e-28 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 107.32 E-value: 9.74e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF--KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGI-----KISKMKREIGY 75
Cdd:cd03251 1 VEFKNVTFRYpgDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHdvrdyTLASLRRQIGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHwMTARETLTFmGQLSGLKKE-----------ELSKSIPKILE-KVGLRGeenskvGTFSGGMKQRLGIAQA 143
Cdd:cd03251 81 VSQDVFLFN-DTVAENIAY-GRPGATREEveeaaraanahEFIMELPEGYDtVIGERG------VKLSGGQRQRIAIARA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEIcerfVIIKDGTKIEDTTITELLQRN 219
Cdd:cd03251 153 LLKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIAHRLStieNADRI----VVLEDGKIVERGTHEELLAQG 227
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-218 |
1.00e-27 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 107.69 E-value: 1.00e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIIN--PNA---GEVLLNGIKISKM-----KR 71
Cdd:PRK14247 3 KIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElyPEArvsGEVYLDGQDIFKMdvielRR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 72 EIGYLPQYPNFFHWMTARETLTFMGQLSGL--KKEELSKSIPKILEKVGLRGEE----NSKVGTFSGGMKQRLGIAQALL 145
Cdd:PRK14247 83 RVQMVFQIPNPIPNLSIFENVALGLKLNRLvkSKKELQERVRWALEKAQLWDEVkdrlDAPAGKLSGGQQQRLCIARALA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 146 HKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:PRK14247 163 FQPEVLLADEPTANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTN 235
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
3-221 |
2.75e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 107.12 E-value: 2.75e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG---KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIG 74
Cdd:PRK13650 5 IEVKNLTFKYKEdqeKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEenvwdIRHKIG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:PRK13650 85 MVFQNPdNQFVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIIL 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILsDAEEICERFVIIKDGtKIEDT-TITELLQRNSE 221
Cdd:PRK13650 165 DEATSMLDPEGRLELIKTIKGIRDDyqMTVISITHDL-DEVALSDRVLVMKNG-QVESTsTPRELFSRGND 233
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
3-218 |
3.33e-27 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 111.07 E-value: 3.33e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGK--IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGY 75
Cdd:PRK11160 339 LTLNNVSFTYPDQpqPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADyseaaLRQAISV 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHwMTARETLTFMGQLSGlkKEELSKsipkILEKVGLR----GEE--NSKVG----TFSGGMKQRLGIAQALL 145
Cdd:PRK11160 419 VSQRVHLFS-ATLRDNLLLAAPNAS--DEALIE----VLQQVGLEklleDDKglNAWLGeggrQLSGGEQRRLGIARALL 491
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 146 HKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEIcERFVIIKDGTKIEDTTITELLQR 218
Cdd:PRK11160 492 HDAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQELLAQ 563
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
18-216 |
4.10e-27 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 106.69 E-value: 4.10e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 18 VNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE----------------IGYL-PQYp 80
Cdd:PRK10419 28 LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAqrkafrrdiqmvfqdsISAVnPRK- 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 81 nffhwmTARETLTF-MGQLSGLKKEELSKSIPKILEKVGLRGEENSKV-GTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:PRK10419 107 ------TVREIIREpLRHLLSLDKAERLARASEMLRAVDLDDSVLDKRpPQLSGGQLQRVCLARALAVEPKLLILDEAVS 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 159 ALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:PRK10419 181 NLDLVLQAGVIRLLKKLQQqfGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPVGDKL 240
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
3-216 |
4.84e-27 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 106.86 E-value: 4.84e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-------KMKREIG 74
Cdd:PRK13636 6 LKVEELNYNYSdGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDysrkglmKLRESVG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:PRK13636 86 MVFQDPdNQLFSASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVL 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:PRK13636 166 DEPTAGLDPMGVSEIMKLLVEMQKelGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
1-263 |
4.89e-27 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 107.09 E-value: 4.89e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKI-----AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEV--LLNGIKISK----- 68
Cdd:PRK13651 1 MQIKVKNIVKIFNKKLptelkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewIFKDEKNKKktkek 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 69 ----------------------MKREIGYLPQYPNFFHWMTARETLTFMGQLS-GLKKEELSKSIPKILEKVGLrGEENS 125
Cdd:PRK13651 81 ekvleklviqktrfkkikkikeIRRRVGVVFQFAEYQLFEQTIEKDIIFGPVSmGVSKEEAKKRAAKYIELVGL-DESYL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 126 KVGTF--SGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI-KKDTTILLSTHILSDAEEICERFVIIK 202
Cdd:PRK13651 160 QRSPFelSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLnKQGKTIILVTHDLDNVLEWTKRTIFFK 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 203 DGTKIEDTTITELLqrnSENKLIIEITAKDQKWIDVVKKLpyvkdvEVIGLKVKvKVESIE 263
Cdd:PRK13651 240 DGKIIKDGDTYDIL---SDNKFLIENNMEPPKLLNFVNKL------EKKGIDVP-KVTSIE 290
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
3-218 |
5.42e-27 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 105.94 E-value: 5.42e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF-KG----KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----RE 72
Cdd:COG1101 2 LELKNLSKTFnPGtvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPeykraKY 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 73 IGYLPQYP------NffhwMTARETLTfMGQLSGlKKEELSKSIPK--------ILEKVGLrGEEN---SKVGTFSGGMK 135
Cdd:COG1101 82 IGRVFQDPmmgtapS----MTIEENLA-LAYRRG-KRRGLRRGLTKkrrelfreLLATLGL-GLENrldTKVGLLSGGQR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 136 QRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIED---- 209
Cdd:COG1101 155 QALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIveENNLTTLMVTHNMEQALDYGNRLIMMHEGRIILDvsge 234
|
250
....*....|...
gi 1261024142 210 ----TTITELLQR 218
Cdd:COG1101 235 ekkkLTVEDLLEL 247
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
1-207 |
8.27e-27 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 103.78 E-value: 8.27e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKG------KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNA--GEVLLNGIKISKM--K 70
Cdd:cd03213 2 VTLSFRNLTVTVKSspsksgKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGvsGEVLINGRPLDKRsfR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 REIGYLPQYPNFFHWMTARETLTFMGQLSGLkkeelsksipkilekvglrgeenskvgtfSGGMKQRLGIAQALLHKPSL 150
Cdd:cd03213 82 KIIGYVPQDDILHPTLTVRETLMFAAKLRGL-----------------------------SGGERKRVSIALELVSNPSL 132
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 151 IVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILS-DAEEICERFVIIKDGTKI 207
Cdd:cd03213 133 LFLDEPTSGLDSSSALQVMSLLRRLADTgRTIICSIHQPSsEIFELFDKLLLLSQGRVI 191
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
15-186 |
9.19e-27 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 109.75 E-value: 9.19e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 15 KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPN---AGEVLLNGIKI--SKMKREIGYLPQYPNFFHWMTAR 89
Cdd:TIGR00955 38 KHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPIdaKEMRAISAYVQQDDLFIPTLTVR 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 90 ETLTFMGQL---SGLKKEELSKSIPKILEKVGLRGEENSKVGT------FSGGMKQRLGIAQALLHKPSLIVMDEPVSAL 160
Cdd:TIGR00955 118 EHLMFQAHLrmpRRVTKKEKRERVDEVLQALGLRKCANTRIGVpgrvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGL 197
|
170 180
....*....|....*....|....*..
gi 1261024142 161 DPIGRREVLNLIEEI-KKDTTILLSTH 186
Cdd:TIGR00955 198 DSFMAYSVVQVLKGLaQKGKTIICTIH 224
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
3-186 |
1.36e-26 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 103.35 E-value: 1.36e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK----REIGYLPQ 78
Cdd:PRK13538 2 LEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRdeyhQDLLYLGH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEElskSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:PRK13538 82 QPGIKTELTALENLRFYQRLHGPGDDE---ALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFT 158
|
170 180
....*....|....*....|....*....
gi 1261024142 159 ALDPIGRREVLNLIEE-IKKDTTILLSTH 186
Cdd:PRK13538 159 AIDKQGVARLEALLAQhAEQGGMVILTTH 187
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
6-186 |
1.42e-26 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 103.89 E-value: 1.42e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 6 RNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNA---GEVLLNG--IKISKMKREIGYLPQYP 80
Cdd:cd03234 11 LKAKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGqpRKPDQFQKCVAYVRQDD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 81 NFFHWMTARETLTFMGQLSG---LKKEELSKSIPKILEK-VGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:cd03234 91 ILLPGLTVRETLTYTAILRLprkSSDAIRKKRVEDVLLRdLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEP 170
|
170 180 190
....*....|....*....|....*....|.
gi 1261024142 157 VSALDPIGRREVLNLIEEI-KKDTTILLSTH 186
Cdd:cd03234 171 TSGLDSFTALNLVSTLSQLaRRNRIVILTIH 201
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
3-162 |
1.75e-26 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 104.43 E-value: 1.75e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYLP 77
Cdd:COG4559 2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSpwelaRRRAVLP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYP--NF-FhwmTARETLTfMGQLSGLKKEELSKSIP-KILEKVGLRGEENSKVGTFSGGMKQRLGIAQALL-------H 146
Cdd:COG4559 82 QHSslAFpF---TVEEVVA-LGRAPHGSSAAQDRQIVrEALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvdG 157
|
170
....*....|....*.
gi 1261024142 147 KPSLIVMDEPVSALDP 162
Cdd:COG4559 158 GPRWLFLDEPTSALDL 173
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
3-186 |
1.91e-26 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 108.60 E-value: 1.91e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG-KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-----KMKREIGYL 76
Cdd:TIGR02868 335 LELRDLSAGYPGaPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSsldqdEVRRRVSVC 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHwMTARETLTF-MGQLSGlkkEELSKSipkiLEKVGL-------RGEENSKVG----TFSGGMKQRLGIAQAL 144
Cdd:TIGR02868 415 AQDAHLFD-TTVRENLRLaRPDATD---EELWAA----LERVGLadwlralPDGLDTVLGeggaRLSGGERQRLALARAL 486
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1261024142 145 LHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTH 186
Cdd:TIGR02868 487 LADAPILLLDEPTEHLDAETADELLEDLLAALSGRTVVLITH 528
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-217 |
6.30e-26 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 103.17 E-value: 6.30e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-----KMKREIGY 75
Cdd:PRK11231 1 MTLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISmlssrQLARRLAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTARET--------LTFMGQLSGLKKEELSKSipkiLEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHK 147
Cdd:PRK11231 81 LPQHHLTPEGITVRELvaygrspwLSLWGRLSAEDNARVNQA----MEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQD 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 148 PSLIVMDEPVSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:PRK11231 157 TPVVLLDEPTTYLDINHQVELMRLMRELNtQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMT 227
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
8-186 |
8.02e-26 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 101.88 E-value: 8.02e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 8 VTKSF-KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK--------REIGYLPQ 78
Cdd:PRK10908 7 VSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKnrevpflrRQIGMIFQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:PRK10908 87 DHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTG 166
|
170 180
....*....|....*....|....*....
gi 1261024142 159 ALDPIGRREVLNLIEEIKK-DTTILLSTH 186
Cdd:PRK10908 167 NLDDALSEGILRLFEEFNRvGVTVLMATH 195
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
18-205 |
9.07e-26 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 106.66 E-value: 9.07e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 18 VNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGYLPQYPNFFHWmTARETL 92
Cdd:TIGR01842 334 LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDREtfgkhIGYLPQDVELFPG-TVAENI 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 93 TFMGQ------------LSGLkkEELSKSIPKILEK-VGLRGEenskvgTFSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:TIGR01842 413 ARFGEnadpekiieaakLAGV--HELILRLPDGYDTvIGPGGA------TLSGGQRQRIALARALYGDPKLVVLDEPNSN 484
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1261024142 160 LDPIGRREVLNLIEEIKK-DTTILLSTH---ILSDAEEIcerfVIIKDGT 205
Cdd:TIGR01842 485 LDEEGEQALANAIKALKArGITVVVITHrpsLLGCVDKI----LVLQDGR 530
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
4-218 |
1.02e-25 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 107.13 E-value: 1.02e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEV-LLNGIKISKMKRE-----IGYLP 77
Cdd:NF033858 3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVeVLGGDMADARHRRavcprIAYMP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 Q------YPNffhwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLI 151
Cdd:NF033858 83 QglgknlYPT----LSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 152 VMDEPVSALDPIGRREVLNLIEEIKKDT---TILLSTHILSDAeeicERF--VIIKDGTKIEDT-TITELLQR 218
Cdd:NF033858 159 ILDEPTTGVDPLSRRQFWELIDRIRAERpgmSVLVATAYMEEA----ERFdwLVAMDAGRVLATgTPAELLAR 227
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
3-204 |
1.06e-25 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 102.78 E-value: 1.06e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAG-----EVLLNGIK--------ISKM 69
Cdd:PRK09984 5 IRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSagshiELLGRTVQregrlardIRKS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYLPQYPNFFHWMTARETL------------TFMGQLSGLKKEELSKSipkiLEKVGLRGEENSKVGTFSGGMKQR 137
Cdd:PRK09984 85 RANTGYIFQQFNLVNRLSVLENVligalgstpfwrTCFSWFTREQKQRALQA----LTRVGMVHFAHQRVSTLSGGQQQR 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 138 LGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDG 204
Cdd:PRK09984 161 VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdgITVVVTLHQVDYALRYCERIVALRQG 229
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
16-216 |
1.12e-25 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 105.12 E-value: 1.12e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 16 IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM---------KREIGYLPQYPNFFHWM 86
Cdd:PRK10070 42 LGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKIsdaelrevrRKKIAMVFQSFALMPHM 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 87 TARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRR 166
Cdd:PRK10070 122 TVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRT 201
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 167 EVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:PRK10070 202 EMQDELVKLqaKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
3-208 |
1.56e-25 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 105.76 E-value: 1.56e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIK-------------ISKM 69
Cdd:PRK11288 5 LSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEmrfasttaalaagVAII 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYLPQypnffhwMTARETLtFMGQLSG----LKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALL 145
Cdd:PRK11288 85 YQELHLVPE-------MTVAENL-YLGQLPHkggiVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 146 HKPSLIVMDEPVSALDpigRREVLNL---IEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:PRK11288 157 RNARVIAFDEPTSSLS---AREIEQLfrvIRELRAEgRVILYVSHRMEEIFALCDAITVFKDGRYVA 220
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
3-213 |
1.65e-25 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 101.43 E-value: 1.65e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-GKI---AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM--------- 69
Cdd:PRK11629 6 LQCDNLCKRYQeGSVqtdVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLssaakaelr 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPS 149
Cdd:PRK11629 86 NQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPR 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 150 LIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEIcERFVIIKDGTKIEDTTIT 213
Cdd:PRK11629 166 LVLADEPTGNLDARNADSIFQLLGELnrLQGTAFLVVTHDLQLAKRM-SRQLEMRDGRLTAELSLM 230
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
4-236 |
1.86e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 101.99 E-value: 1.86e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGYL 76
Cdd:PRK13632 9 KVENVSFSYPNseNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKenlkeIRKKIGII 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:PRK13632 89 FQNPdNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 156 PVSALDPIGRREVLNLIEEIKKDT--TILLSTHilsDAEEI--CERFVIIKDGTKIEDTTITELLqrnsENKLIIEITAK 231
Cdd:PRK13632 169 STSMLDPKGKREIKKIMVDLRKTRkkTLISITH---DMDEAilADKVIVFSEGKLIAQGKPKEIL----NNKEILEKAKI 241
|
....*
gi 1261024142 232 DQKWI 236
Cdd:PRK13632 242 DSPFI 246
|
|
| CP_lyasePhnL |
TIGR02324 |
phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P ... |
3-202 |
2.85e-25 |
|
phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated C-P lysase complex. This protein (PhnL) and the adjacent-encoded PhnK (TIGR02323) resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this C-P lyase complex rather than part of a transporter per se.
Pssm-ID: 131377 [Multi-domain] Cd Length: 224 Bit Score: 100.54 E-value: 2.85e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF-----KGKI--AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLN---------GIKI 66
Cdd:TIGR02324 2 LEVEDLSKTFtlhqqGGVRlpVLKNVSLTVNAGECVALSGPSGAGKSTLLKSLYANYLPDSGRILVRhegawvdlaQASP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 67 SKM----KREIGYLPQYPNFFHWMTARETLTFMGQLSGLKKEE--------LSK-SIPKILEKVglrgeensKVGTFSGG 133
Cdd:TIGR02324 82 REVlevrRKTIGYVSQFLRVIPRVSALEVVAEPLLERGVPREAarararelLARlNIPERLWHL--------PPATFSGG 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 134 MKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSthILSDAE---EICERFVIIK 202
Cdd:TIGR02324 154 EQQRVNIARGFIADYPILLLDEPTASLDAANRQVVVELIAEAKARGAALIG--IFHDEEvreLVADRVMDVT 223
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
5-217 |
3.03e-25 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 101.40 E-value: 3.03e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYLPQY 79
Cdd:PRK10575 14 LRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSskafaRKVAYLPQQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 80 PNFFHWMTARETLTF--------MGQLSGLKKEELSKSIpkilEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLI 151
Cdd:PRK10575 94 LPAAEGMTVRELVAIgrypwhgaLGRFGAADREKVEEAI----SLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 152 VMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:PRK10575 170 LLDEPTSALDIAHQVDVLALVHRLsqERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMR 237
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
3-221 |
4.12e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 101.37 E-value: 4.12e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIA--VNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-----KMKREIGY 75
Cdd:PRK13648 8 IVFKNVSFQYQSDASftLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITddnfeKLRKHIGI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:PRK13648 88 VFQNPdNQFVGSIVKYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILD 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIK--KDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRNSE 221
Cdd:PRK13648 168 EATSMLDPDARQNLLDLVRKVKseHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDHAEE 235
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
2-219 |
7.13e-25 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 104.03 E-value: 7.13e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIG 74
Cdd:TIGR02203 330 DVEFRNVTFRYPGrdRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADytlasLRRQVA 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHwMTARETLTFmGQLSGLKKEELSKSI--PKILEKV-----GLRGEENSKVGTFSGGMKQRLGIAQALLHK 147
Cdd:TIGR02203 410 LVSQDVVLFN-DTIANNIAY-GRTEQADRAEIERALaaAYAQDFVdklplGLDTPIGENGVLLSGGQRQRLAIARALLKD 487
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 148 PSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRN 219
Cdd:TIGR02203 488 APILILDEATSALDNESERLVQAALERLMQGRTTLVIAHRLSTIEK-ADRIVVMDDGRIVERGTHNELLARN 558
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
3-192 |
9.53e-25 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 98.72 E-value: 9.53e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK----REIGYLPQ 78
Cdd:cd03231 1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRdsiaRGLLYLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGlkkeelSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:cd03231 81 APGIKTTLSVLENLRFWHADHS------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTT 154
|
170 180 190
....*....|....*....|....*....|....*....
gi 1261024142 159 ALDPIGrreVLNLIEEIKKDT----TILLSTHI-LSDAE 192
Cdd:cd03231 155 ALDKAG---VARFAEAMAGHCarggMVVLTTHQdLGLSE 190
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
3-207 |
1.63e-24 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 102.94 E-value: 1.63e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM------KREIGYL 76
Cdd:PRK09700 6 ISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLdhklaaQLGIGII 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLtFMGQLSGLKK--------EELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKP 148
Cdd:PRK09700 86 YQELSVIDELTVLENL-YIGRHLTKKVcgvniidwREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 149 SLIVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKI 207
Cdd:PRK09700 165 KVIIMDEPTSSLTNKEVDYLFLIMNQLRKEgTAIVYISHKLAEIRRICDRYTVMKDGSSV 224
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
15-216 |
1.69e-24 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 99.35 E-value: 1.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 15 KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG-----------IKISKMKREIGYLPQYPNFF 83
Cdd:PRK14246 23 KAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGkvlyfgkdifqIDAIKLRKEVGMVFQQPNPF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 84 HWMTARETLTFMGQLSGLK-KEELSKSIPKILEKVGLRGEE----NSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:PRK14246 103 PHLSIYDNIAYPLKSHGIKeKREIKKIVEECLRKVGLWKEVydrlNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTS 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 159 ALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:PRK14246 183 MIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIF 240
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
3-225 |
1.88e-24 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 102.70 E-value: 1.88e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIInPNA---GEVLLNG-------IK------I 66
Cdd:PRK13549 6 LEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVY-PHGtyeGEIIFEGeelqasnIRdteragI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 67 SKMKREIGYLPQypnffhwMTARETLtFMGqlsglkkEELSKS-----------IPKILEKVGLRGEENSKVGTFSGGMK 135
Cdd:PRK13549 85 AIIHQELALVKE-------LSVLENI-FLG-------NEITPGgimdydamylrAQKLLAQLKLDINPATPVGNLGLGQQ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 136 QRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITE 214
Cdd:PRK13549 150 QLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKaHGIACIYISHKLNEVKAISDTICVIRDGRHIGTRPAAG 229
|
250
....*....|.
gi 1261024142 215 LlqrnSENKLI 225
Cdd:PRK13549 230 M----TEDDII 236
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
1-208 |
2.14e-24 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 98.55 E-value: 2.14e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIK-----------ISKM 69
Cdd:COG4161 1 MSIQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQfdfsqkpsekaIRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYLPQYPNFFHWMTARETLTFMG-QLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKP 148
Cdd:COG4161 81 RQKVGMVFQQYNLWPHLTVMENLIEAPcKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEP 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 149 SLIVMDEPVSALDPIGRREVLNLIEEIKK-DTTILLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:COG4161 161 QVLLFDEPTAALDPEITAQVVEIIRELSQtGITQVIVTHEVEFARKVASQVVYMEKGRIIE 221
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
3-221 |
2.30e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 99.40 E-value: 2.30e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNF---SMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-----KMKREIG 74
Cdd:PRK13642 5 LEVENLVFKYEKESDVNQLngvSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTaenvwNLRRKIG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:PRK13642 85 MVFQNPdNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIIL 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRNSE 221
Cdd:PRK13642 165 DESTSMLDPTGRQEIMRVIHEIKEKyqLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSED 233
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
3-204 |
3.68e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 98.65 E-value: 3.68e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGYL 76
Cdd:PRK13647 5 IEVEDLHFRYKdGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAenekwVRSKVGLV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPN--FFHwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:PRK13647 85 FQDPDdqVFS-STVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLD 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDG 204
Cdd:PRK13647 164 EPMAYLDPRGQETLMEILDRLHNQgKTVIVATHDVDLAAEWADQVIVLKEG 214
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
1-208 |
6.43e-24 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 97.39 E-value: 6.43e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIK-----------ISKM 69
Cdd:PRK11124 1 MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHfdfsktpsdkaIREL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYLPQYPNFFHWMTARETLTFMG-QLSGLKKEELSKSIPKILEKVGLrgeeNSKVGTF----SGGMKQRLGIAQAL 144
Cdd:PRK11124 81 RRNVGMVFQQYNLWPHLTVQQNLIEAPcRVLGLSKDQALARAEKLLERLRL----KPYADRFplhlSGGQQQRVAIARAL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 145 LHKPSLIVMDEPVSALDPIGRREVLNLIEEIkKDTTI--LLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:PRK11124 157 MMEPQVLLFDEPTAALDPEITAQIVSIIREL-AETGItqVIVTHEVEVARKTASRVVYMENGHIVE 221
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
3-218 |
7.59e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 97.95 E-value: 7.59e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGYL 76
Cdd:PRK13652 4 IETRDLCYSYSGSKeALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKenireVRKFVGLV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLS-GLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:PRK13652 84 FQNPDDQIFSPTVEQDIAFGPINlGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDE 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 156 PVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:PRK13652 164 PTAGLDPQGVKELIDFLNDLPETygMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQ 228
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
2-204 |
8.69e-24 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 96.77 E-value: 8.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIAVN---NFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REI 73
Cdd:cd03248 11 IVKFQNVTFAYPTRPDTLvlqDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEhkylhSKV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 GYLPQYPNFFHwMTARETLTF-MGQLS-GLKKEELSKS-----IPKiLEKvGLRGEENSKVGTFSGGMKQRLGIAQALLH 146
Cdd:cd03248 91 SLVGQEPVLFA-RSLQDNIAYgLQSCSfECVKEAAQKAhahsfISE-LAS-GYDTEVGEKGSQLSGGQKQRVAIARALIR 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 147 KPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDG 204
Cdd:cd03248 168 NPQVLILDEATSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVER-ADQILVLDGG 224
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-191 |
1.40e-23 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 97.16 E-value: 1.40e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKV---ISDIInPNA---GEVLLNGIKI-------SK 68
Cdd:PRK14243 10 VLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCfnrLNDLI-PGFrveGKVTFHGKNLyapdvdpVE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 69 MKREIGYLPQYPNFFHwMTARETLTFMGQLSGLKKEeLSKSIPKILEKVGLRGEENSKVGT----FSGGMKQRLGIAQAL 144
Cdd:PRK14243 89 VRRRIGMVFQKPNPFP-KSIYDNIAYGARINGYKGD-MDELVERSLRQAALWDEVKDKLKQsglsLSGGQQQRLCIARAI 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1261024142 145 LHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDA 191
Cdd:PRK14243 167 AVQPEVILMDEPCSALDPISTLRIEELMHELKEQYTIIIVTHNMQQA 213
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
4-219 |
1.44e-23 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 100.42 E-value: 1.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGYLP 77
Cdd:PRK13657 336 EFDDVSFSYDNSRqGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRAslrrnIAVVF 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPNFFHWMTA------RETLTFMGQLSGLKKEELSKSIPKILEK----VGLRGeenskvGTFSGGMKQRLGIAQALLHK 147
Cdd:PRK13657 416 QDAGLFNRSIEdnirvgRPDATDEEMRAAAERAQAHDFIERKPDGydtvVGERG------RQLSGGERQRLAIARALLKD 489
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 148 PSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEIcerfVIIKDGTKIEDTTITELLQRN 219
Cdd:PRK13657 490 PPILILDEATSALDVETEAKVKAALDELMKGRTTFIIAHRLStvrNADRI----LVFDNGRVVESGSFDELVARG 560
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
1-194 |
1.66e-23 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 95.33 E-value: 1.66e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGikiskmkREIGYlPQYP 80
Cdd:PRK13539 1 MMLEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDG-------GDIDD-PDVA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 81 NFFHW----------MTARETLTFMGQLSGlkKEELskSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSL 150
Cdd:PRK13539 73 EACHYlghrnamkpaLTVAENLEFWAAFLG--GEEL--DIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPI 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1261024142 151 IVMDEPVSALDPIGRREVLNLIEE-IKKDTTILLSTHI---LSDAEEI 194
Cdd:PRK13539 149 WILDEPTAALDAAAVALFAELIRAhLAQGGIVIAATHIplgLPGAREL 196
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
3-205 |
2.79e-23 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 92.90 E-value: 2.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVllngikISKMKREIGYLPQypnf 82
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV------TWGSTVKIGYFEQ---- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 fhwmtaretltfmgqlsglkkeelsksipkilekvglrgeenskvgtFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDP 162
Cdd:cd03221 71 -----------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDL 103
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1261024142 163 IGRREVLNLIEEIKKdtTILLSTHilsDAE---EICERFVIIKDGT 205
Cdd:cd03221 104 ESIEALEEALKEYPG--TVILVSH---DRYfldQVATKIIELEDGK 144
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
3-218 |
3.80e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 96.02 E-value: 3.80e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG--KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGE---VLLNGIKISK-----MKRE 72
Cdd:PRK13640 6 VEFKHVSFTYPDskKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPnskITVDGITLTAktvwdIREK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 73 IGYLPQYP-NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLI 151
Cdd:PRK13640 86 VGIVFQNPdNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKII 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 152 VMDEPVSALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFV-----IIKDGTKIEDTTITELLQR 218
Cdd:PRK13640 166 ILDESTSMLDPAGKEQILKLIRKLKKKNnlTVISITHDIDEANMADQVLVlddgkLLAQGSPVEIFSKVEMLKE 239
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
3-220 |
6.85e-23 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 94.48 E-value: 6.85e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK--GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGY 75
Cdd:cd03252 1 ITFEHVRFRYKpdGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALadpawLRRQVGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTA-----------RETLTFMGQLSGlkKEELSKSIPKILEK-VGLRGeenskVGtFSGGMKQRLGIAQA 143
Cdd:cd03252 81 VLQENVLFNRSIRdnialadpgmsMERVIEAAKLAG--AHDFISELPEGYDTiVGEQG-----AG-LSGGQRQRIAIARA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRNS 220
Cdd:cd03252 153 LIHNPRILIFDEATSALDYESEHAIMRNMHDICAGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAENG 228
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
2-208 |
1.02e-22 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 93.71 E-value: 1.02e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFK--GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IG 74
Cdd:cd03244 2 DIEFKNVSLRYRpnLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHdlrsrIS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHwMTARETLTFMGQLSglkKEELSKsipkILEKVGLRGEENSKVGT-----------FSGGMKQRLGIAQA 143
Cdd:cd03244 82 IIPQDPVLFS-GTIRSNLDPFGEYS---DEELWQ----ALERVGLKEFVESLPGGldtvveeggenLSVGQRQLLCLARA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTH----ILSdaeeiCERFVIIKDGTKIE 208
Cdd:cd03244 154 LLRKSKILVLDEATASVDPETDALIQKTIREAFKDCTVLTIAHrldtIID-----SDRILVLDKGRVVE 217
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
17-215 |
1.15e-22 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 95.93 E-value: 1.15e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM--------KREIGYLPQYP--NFFHWM 86
Cdd:PRK15079 36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMkddewravRSDIQMIFQDPlaSLNPRM 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 87 T-----ARETLTFMGQLSglkKEELSKSIPKILEKVGLRGEE-NSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSAL 160
Cdd:PRK15079 116 TigeiiAEPLRTYHPKLS---RQEVKDRVKAMMLKVGLLPNLiNRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSAL 192
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 161 DPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:PRK15079 193 DVSIQAQVVNLLQQLQREMglSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEV 249
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
17-217 |
1.68e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 94.80 E-value: 1.68e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGI---------KISKMKREIGYLPQYP--NFFHw 85
Cdd:PRK13643 21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIvvsstskqkEIKPVRKKVGVVFQFPesQLFE- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 86 MTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGE--ENSKVgTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPI 163
Cdd:PRK13643 100 ETVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADEfwEKSPF-ELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPK 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 164 GRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:PRK13643 179 ARIEMMQLFESIHQSgQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQ 233
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
3-208 |
1.69e-22 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 97.06 E-value: 1.69e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGK-----------IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIInPNAGEVLLNGIKISKMK- 70
Cdd:COG4172 276 LEARDLKVWFPIKrglfrrtvghvKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLDGLSr 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 -------REI--------GYL-PQypnffhwMTARETLT--FMGQLSGLKKEELSKSIPKILEKVGLRGE-------Ens 125
Cdd:COG4172 355 ralrplrRRMqvvfqdpfGSLsPR-------MTVGQIIAegLRVHGPGLSAAERRARVAEALEEVGLDPAarhryphE-- 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 126 kvgtFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKD 203
Cdd:COG4172 426 ----FSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLqrEHGLAYLFISHDLAVVRALAHRVMVMKD 501
|
....*
gi 1261024142 204 GTKIE 208
Cdd:COG4172 502 GKVVE 506
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
3-217 |
1.84e-22 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 97.22 E-value: 1.84e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRN-VTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIInPNAGEVLLNGIKISKM-----KREIGYL 76
Cdd:PRK11174 350 IEAEDlEILSPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIELRELdpeswRKHLSWV 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHwMTARETLTfMGQlSGLKKEELSKSIPK--ILEKV-----GLR---GEENSKVgtfSGGMKQRLGIAQALLH 146
Cdd:PRK11174 429 GQNPQLPH-GTLRDNVL-LGN-PDASDEQLQQALENawVSEFLpllpqGLDtpiGDQAAGL---SVGQAQRLALARALLQ 502
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 147 KPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQ 217
Cdd:PRK11174 503 PCQLLLLDEPTASLDAHSEQLVMQALNAASRRQTTLMVTHQLEDLAQ-WDQIWVMQDGQIVQQGDYAELSQ 572
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
5-186 |
2.07e-22 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 97.26 E-value: 2.07e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPN--AGEVLLNGIKISK--MKReIGYLPQYP 80
Cdd:PLN03211 71 ISDETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPTKqiLKR-TGFVTQDD 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 81 NFFHWMTARETLTFMGQL---SGLKKEELSKSIPKILEKVGLRGEENSKVG-TF----SGGMKQRLGIAQALLHKPSLIV 152
Cdd:PLN03211 150 ILYPHLTVRETLVFCSLLrlpKSLTKQEKILVAESVISELGLTKCENTIIGnSFirgiSGGERKRVSIAHEMLINPSLLI 229
|
170 180 190
....*....|....*....|....*....|....*
gi 1261024142 153 MDEPVSALDPIGR-REVLNLIEEIKKDTTILLSTH 186
Cdd:PLN03211 230 LDEPTSGLDATAAyRLVLTLGSLAQKGKTIVTSMH 264
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
3-186 |
2.12e-22 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 96.80 E-value: 2.12e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVT-KSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGikiskmKREIGYLPQYPn 81
Cdd:COG4178 363 LALEDLTlRTPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARPA------GARVLFLPQRP- 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 82 FFHWMTARETLTFMGQLSGLKKEELSKsipkILEKVGL-----R-GEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:COG4178 436 YLPLGTLREALLYPATAEAFSDAELRE----ALEAVGLghlaeRlDEEADWDQVLSLGEQQRLAFARLLLHKPDWLFLDE 511
|
170 180 190
....*....|....*....|....*....|.
gi 1261024142 156 PVSALDPIGRREVLNLIEEIKKDTTILLSTH 186
Cdd:COG4178 512 ATSALDEENEAALYQLLREELPGTTVISVGH 542
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
3-218 |
2.23e-22 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 96.68 E-value: 2.23e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG----KIAVNNFSMELQSGECVGLIGPNGAGKS----TLIKVISDIINPNAGEVLLNGIKISKMK---- 70
Cdd:COG4172 7 LSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLGLSerel 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 -----REIGYLPQYPnffhwMTA-----------RETLTFMGqlsGLKKEELSKSIPKILEKVGLRGEEnSKVGTF---- 130
Cdd:COG4172 87 rrirgNRIAMIFQEP-----MTSlnplhtigkqiAEVLRLHR---GLSGAAARARALELLERVGIPDPE-RRLDAYphql 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 131 SGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:COG4172 158 SGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELgmALLLITHDLGVVRRFADRVAVMRQGEIVE 237
|
250
....*....|
gi 1261024142 209 DTTITELLQR 218
Cdd:COG4172 238 QGPTAELFAA 247
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
3-255 |
2.75e-22 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 96.27 E-value: 2.75e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK----REIG-YL- 76
Cdd:PRK15439 12 LCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTpakaHQLGiYLv 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFmgqlsGL-KKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDE 155
Cdd:PRK15439 92 PQEPLLFPNLSVKENILF-----GLpKRQASMQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILILDE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 156 PVSALDPIgrrEVLNLIEEIK----KDTTILLSTHILSDAEEICERFVIIKDGT-----KIEDTTITELLQRNSENKLII 226
Cdd:PRK15439 167 PTASLTPA---ETERLFSRIRellaQGVGIVFISHKLPEIRQLADRISVMRDGTialsgKTADLSTDDIIQAITPAAREK 243
|
250 260
....*....|....*....|....*....
gi 1261024142 227 EITAKDQKWIDvvkkLPYVKDVEVIGLKV 255
Cdd:PRK15439 244 SLSASQKLWLE----LPGNRRQQAAGAPV 268
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
2-218 |
3.06e-22 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 96.71 E-value: 3.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIAV---NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREI 73
Cdd:TIGR00958 478 LIEFQDVSFSYPNRPDVpvlKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQydhhyLHRQV 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 GYLPQYPNFFHwMTARETLTF------MGQLSGLKKEELSKSIPKILEKvGLRGEENSKVGTFSGGMKQRLGIAQALLHK 147
Cdd:TIGR00958 558 ALVGQEPVLFS-GSVRENIAYgltdtpDEEIMAAAKAANAHDFIMEFPN-GYDTEVGEKGSQLSGGQKQRIAIARALVRK 635
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 148 PSLIVMDEPVSALDPIGRREVLNLIEeiKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQR 218
Cdd:TIGR00958 636 PRVLILDEATSALDAECEQLLQESRS--RASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMED 703
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
3-225 |
3.32e-22 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 96.23 E-value: 3.32e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAG-------EVLLNGIK------ISKM 69
Cdd:PRK10762 5 LQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGsilylgkEVTFNGPKssqeagIGII 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYLPQYP---NFFhwmTAREtltFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLH 146
Cdd:PRK10762 85 HQELNLIPQLTiaeNIF---LGRE---FVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 147 KPSLIVMDEPVSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELlqrnSENKLI 225
Cdd:PRK10762 159 ESKVIIMDEPTDALTDTETESLFRVIRELKsQGRGIVYISHRLKEIFEICDDVTVFRDGQFIAEREVADL----TEDSLI 234
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
3-216 |
3.42e-22 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 93.32 E-value: 3.42e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKI---------AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKI-----SK 68
Cdd:PRK15112 5 LEVRNLSKTFRYRTgwfrrqtveAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLhfgdySY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 69 MKREIGYLPQYPNffhwmTARETLTFMGQL--------SGLKKEELSKSIPKILEKVGLRGEENSKV-GTFSGGMKQRLG 139
Cdd:PRK15112 85 RSQRIRMIFQDPS-----TSLNPRQRISQIldfplrlnTDLEPEQREKQIIETLRQVGLLPDHASYYpHMLAPGQKQRLG 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 140 IAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:PRK15112 160 LARALILRPKVIIADEALASLDMSMRSQLINLMLELqeKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVL 238
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
3-210 |
4.44e-22 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 92.25 E-value: 4.44e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFkGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK------MKREIGY 75
Cdd:PRK11614 6 LSFDKVSAHY-GKIqALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDwqtakiMREAVAI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTARETLTFMGQLSglKKEELSKSIPKILEKVG-LRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:PRK11614 85 VPEGRRVFSRMTVEENLAMGGFFA--ERDQFQERIKWVYELFPrLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDG-TKIEDT 210
Cdd:PRK11614 163 EPSLGLAPIIIQQIFDTIEQLREQgMTIFLVEQNANQALKLADRGYVLENGhVVLEDT 220
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
3-215 |
4.80e-22 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 94.42 E-value: 4.80e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLiKVISDIINPNAGE----VLLNGIKISKMKREIG-YLP 77
Cdd:NF000106 14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRrpwrF*TWCANRRALRRTIG*HRP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPV 157
Cdd:NF000106 93 VR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPT 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 158 SALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:NF000106 173 TGLDPRTRNEVWDEVRSMVRDgATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
3-208 |
5.15e-22 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 92.59 E-value: 5.15e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEV--------LLNGIKISKMKR--- 71
Cdd:TIGR02323 4 LQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTAtyimrsgaELELYQLSEAERrrl 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 72 ---EIGYLPQYPNFFHWMTAR------ETLTFMGQLsglKKEELSKSIPKILEKVGL-RGEENSKVGTFSGGMKQRLGIA 141
Cdd:TIGR02323 84 mrtEWGFVHQNPRDGLRMRVSaganigERLMAIGAR---HYGNIRATAQDWLEEVEIdPTRIDDLPRAFSGGMQQRLQIA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 142 QALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTI--LLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:TIGR02323 161 RNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLavIIVTHDLGVARLLAQRLLVMQQGRVVE 229
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
3-186 |
6.61e-22 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 92.05 E-value: 6.61e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIIN--PNAGEVLLNGIKISKM------KREIG 74
Cdd:COG0396 1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKyeVTSGSILLDGEDILELspderaRAGIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYP---------NFFHwmTARETLTfmgqLSGLKKEELSKSIPKILEKVGLRGEENSK---VGtFSGGMKQRLGIAQ 142
Cdd:COG0396 81 LAFQYPveipgvsvsNFLR--TALNARR----GEELSAREFLKLLKEKMKELGLDEDFLDRyvnEG-FSGGEKKRNEILQ 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1261024142 143 ALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIK-KDTTILLSTH 186
Cdd:COG0396 154 MLLLEPKLAILDETDSGLDIDALRIVAEGVNKLRsPDRGILIITH 198
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
3-219 |
8.64e-22 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 95.19 E-value: 8.64e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK-GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGYL 76
Cdd:TIGR01193 474 IVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDidrhtLRQFINYL 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWmTARETLtFMGQLSGLKKEELSKS-----IPKILEKV--GLRGEENSKVGTFSGGMKQRLGIAQALLHKPS 149
Cdd:TIGR01193 554 PQEPYIFSG-SILENL-LLGAKENVSQDEIWAAceiaeIKDDIENMplGYQTELSEEGSSISGGQKQRIALARALLTDSK 631
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 150 LIVMDEPVSALDPIGRREVLNLIEEIkKDTTILLSTHILSDAEEIcERFVIIKDGTKIEDTTITELLQRN 219
Cdd:TIGR01193 632 VLILDESTSNLDTITEKKIVNNLLNL-QDKTIIFVAHRLSVAKQS-DKIIVLDHGKIIEQGSHDELLDRN 699
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
3-221 |
1.03e-21 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 92.14 E-value: 1.03e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGY------- 75
Cdd:PRK11831 8 VDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYtvrkrms 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 -LPQYPNFFHWMTARETLTF-MGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:PRK11831 88 mLFQSGALFTDMNVFDNVAYpLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMF 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITElLQRNSE 221
Cdd:PRK11831 168 DEPFVGQDPITMGVLVKLISELNSalGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQA-LQANPD 236
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
3-194 |
1.59e-21 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 92.33 E-value: 1.59e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKS-------FKGKI---AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK---- 68
Cdd:PRK11308 6 LQAIDLKKHypvkrglFKPERlvkALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKadpe 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 69 ----MKREIGYLPQYPnfFHWMTARETLtfmGQL--------SGLKKEELSKSIPKILEKVGLRGEENSKV-GTFSGGMK 135
Cdd:PRK11308 86 aqklLRQKIQIVFQNP--YGSLNPRKKV---GQIleepllinTSLSAAERREKALAMMAKVGLRPEHYDRYpHMFSGGQR 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 136 QRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEI 194
Cdd:PRK11308 161 QRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQElgLSYVFISHDLSVVEHI 221
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-204 |
1.61e-21 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 93.37 E-value: 1.61e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-----KMKREIGY 75
Cdd:PRK09536 2 PMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEalsarAASRRVAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTARETLTfMGQLSGLKK-----EELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSL 150
Cdd:PRK09536 82 VPQDTSLSFEFDVRQVVE-MGRTPHRSRfdtwtETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPV 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 151 IVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDG 204
Cdd:PRK09536 161 LLLDEPTASLDINHQVRTLELVRRLVDDgKTAVAAIHDLDLAARYCDELVLLADG 215
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
3-224 |
1.77e-21 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 91.25 E-value: 1.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIiNPNAGEVLLNG-------------IKISKM 69
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRM-NELESEVRVEGrveffnqniyerrVNLNRL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYLPQYPNFFHwMTARETLTFMGQLSGLK-KEELSKSIPKILEKVGLRGEENSKVGT----FSGGMKQRLGIAQAL 144
Cdd:PRK14258 87 RRQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWRpKLEIDDIVESALKDADLWDEIKHKIHKsaldLSGGQQQRLCIARAL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 145 LHKPSLIVMDEPVSALDPIGRREVLNLIE--EIKKDTTILLSTHILSDAEEICERFVIIKDgtkiEDTTITELLQRNSEN 222
Cdd:PRK14258 166 AVKPKVLLMDEPCFGLDPIASMKVESLIQslRLRSELTMVIVSHNLHQVSRLSDFTAFFKG----NENRIGQLVEFGLTK 241
|
..
gi 1261024142 223 KL 224
Cdd:PRK14258 242 KI 243
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
3-194 |
2.14e-21 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 90.16 E-value: 2.14e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE-----IGYLP 77
Cdd:PRK10247 8 LQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEiyrqqVSYCA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPNFFHwMTARETLTFMGQLSGLKKEElsKSIPKILEKVGLRGEENSK-VGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:PRK10247 88 QTPTLFG-DTVYDNLIFPWQIRNQQPDP--AIFLDDLERFALPDTILTKnIAELSGGEKQRISLIRNLQFMPKVLLLDEI 164
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1261024142 157 VSALDPIGRREVLNLIEEIKKDTTI--LLSTHilsDAEEI 194
Cdd:PRK10247 165 TSALDESNKHNVNEIIHRYVREQNIavLWVTH---DKDEI 201
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
5-188 |
2.46e-21 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 90.56 E-value: 2.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGikiskmKREIGYLPQYPNffh 84
Cdd:PRK09544 7 LENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNG------KLRIGYVPQKLY--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 85 wMTARETLT---FMGQLSGLKKEElsksIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:PRK09544 78 -LDTTLPLTvnrFLRLRPGTKKED----ILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVD 152
|
170 180
....*....|....*....|....*....
gi 1261024142 162 PIGRREVLNLIEEIKK--DTTILLSTHIL 188
Cdd:PRK09544 153 VNGQVALYDLIDQLRRelDCAVLMVSHDL 181
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
17-208 |
4.32e-21 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 93.38 E-value: 4.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKI-----SKM---KREIGYLPQYPnfFHWMTA 88
Cdd:PRK10261 339 AVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIdtlspGKLqalRRDIQFIFQDP--YASLDP 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 89 RET--------LTFMGQLSGlkkEELSKSIPKILEKVGLRGEENSKV-GTFSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:PRK10261 417 RQTvgdsimepLRVHGLLPG---KAAAARVAWLLERVGLLPEHAWRYpHEFSGGQRQRICIARALALNPKVIIADEAVSA 493
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 160 LDPIGRREVLNLIEEIKKDTTI--LLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:PRK10261 494 LDVSIRGQIINLLLDLQRDFGIayLFISHDMAVVERISHRVAVMYLGQIVE 544
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
3-208 |
4.69e-21 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 91.32 E-value: 4.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK---GKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPN---AGEVLLNGIKI--------S 67
Cdd:PRK09473 13 LDVKDLRVTFStpdGDVtAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANgriGGSATFNGREIlnlpekelN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 68 KMKRE-IGYLPQYP--NFFHWMTARETLTFMGQL-SGLKKEELSKSIPKILEKVGLRgEENSKVGT----FSGGMKQRLG 139
Cdd:PRK09473 93 KLRAEqISMIFQDPmtSLNPYMRVGEQLMEVLMLhKGMSKAEAFEESVRMLDAVKMP-EARKRMKMypheFSGGMRQRVM 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 140 IAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:PRK09473 172 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfnTAIIMITHDLGVVAGICDKVLVMYAGRTME 242
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
3-218 |
6.31e-21 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 92.58 E-value: 6.31e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDiINPNA---GEVLLNG--IKISKMK----REI 73
Cdd:TIGR02633 2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSG-VYPHGtwdGEIYWSGspLKASNIRdterAGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 GYLPQYPNFFHWMTARETLtFMGQ---LSG--LKKEELSKSIPKILEKVGLRGEENSK-VGTFSGGMKQRLGIAQALLHK 147
Cdd:TIGR02633 81 VIIHQELTLVPELSVAENI-FLGNeitLPGgrMAYNAMYLRAKNLLRELQLDADNVTRpVGDYGGGQQQLVEIAKALNKQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 148 PSLIVMDEPVSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKI---------EDTTITELLQ 217
Cdd:TIGR02633 160 ARLLILDEPSSSLTEKETEILLDIIRDLKaHGVACVYISHKLNEVKAVCDTICVIRDGQHVatkdmstmsEDDIITMMVG 239
|
.
gi 1261024142 218 R 218
Cdd:TIGR02633 240 R 240
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
4-197 |
6.84e-21 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 92.88 E-value: 6.84e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS----KMKREIGYLPQY 79
Cdd:NF033858 268 EARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDagdiATRRRVGYMSQA 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 80 PNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:NF033858 348 FSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSG 427
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1261024142 160 LDPIGRREVLN-LIEEIKKD-TTILLSTHILSDAEEiCER 197
Cdd:NF033858 428 VDPVARDMFWRlLIELSREDgVTIFISTHFMNEAER-CDR 466
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
3-211 |
7.30e-21 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 89.03 E-value: 7.30e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK---GKIAV-NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM--------- 69
Cdd:COG4181 9 IELRGLTKTVGtgaGELTIlKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALdedararlr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYLPQYpnfFHW---MTARETLTFMGQLSGLKK-EELSKsipKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALL 145
Cdd:COG4181 89 ARHVGFVFQS---FQLlptLTALENVMLPLELAGRRDaRARAR---ALLERVGLGHRLDHYPAQLSGGEQQRVALARAFA 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 146 HKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEiCERFVIIKDGTKIEDTT 211
Cdd:COG4181 163 TEPAILFADEPTGNLDAATGEQIIDLLFELNRErgTTLVLVTHDPALAAR-CDRVLRLRAGRLVEDTA 229
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
1-215 |
1.09e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 89.45 E-value: 1.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSF-KG----KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-------- 67
Cdd:PRK13646 1 MTIRFDNVSYTYqKGtpyeHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITIThktkdkyi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 68 -KMKREIGYLPQYP--NFFHWMTARETLtFMGQLSGLKKEELSKSIPKILEKVGL-RGEENSKVGTFSGGMKQRLGIAQA 143
Cdd:PRK13646 81 rPVRKRIGMVFQFPesQLFEDTVEREII-FGPKNFKMNLDEVKNYAHRLLMDLGFsRDVMSQSPFQMSGGQMRKIAIVSI 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:PRK13646 160 LAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLqtDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKEL 233
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
3-204 |
1.66e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 88.89 E-value: 1.66e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF-KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGI------KISKMKREIGY 75
Cdd:PRK13644 2 IRLENVSYSYpDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIdtgdfsKLQGIRKLVGI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNF-FHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:PRK13644 82 VFQNPETqFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFD 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 155 EPVSALDPIGRREVLNLIEEI-KKDTTILLSTHILSDAeEICERFVIIKDG 204
Cdd:PRK13644 162 EVTSMLDPDSGIAVLERIKKLhEKGKTIVYITHNLEEL-HDADRIIVMDRG 211
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
2-208 |
1.84e-20 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 88.32 E-value: 1.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFkGKIAV-NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS------------- 67
Cdd:COG4598 8 ALEVRDLHKSF-GDLEVlKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRlkpdrdgelvpad 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 68 -----KMKREIGYLPQypNFFHW--MTARETLTFMG-QLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLG 139
Cdd:COG4598 87 rrqlqRIRTRLGMVFQ--SFNLWshMTVLENVIEAPvHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 140 IAQALLHKPSLIVMDEPVSALDPIGRREVL----NLIEEIKkdtTILLSTHILSDAEEICERFVIIKDGtKIE 208
Cdd:COG4598 165 IARALAMEPEVMLFDEPTSALDPELVGEVLkvmrDLAEEGR---TMLVVTHEMGFARDVSSHVVFLHQG-RIE 233
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
2-209 |
1.89e-20 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 88.49 E-value: 1.89e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYLP---- 77
Cdd:PRK10619 5 KLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLKvadk 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 --------------QYPNFFHWMTARETLTFMG-QLSGLKKEELSKSIPKILEKVGLRGEENSKVGT-FSGGMKQRLGIA 141
Cdd:PRK10619 85 nqlrllrtrltmvfQHFNLWSHMTVLENVMEAPiQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVhLSGGQQQRVSIA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 142 QALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDGtKIED 209
Cdd:PRK10619 165 RALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEgKTMVVVTHEMGFARHVSSHVIFLHQG-KIEE 232
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
7-216 |
2.43e-20 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 88.61 E-value: 2.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 7 NVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINP-----NAGEVLLNGIKIS------KMKREIGY 75
Cdd:PRK14271 26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKvsgyrYSGDVLLGGRSIFnyrdvlEFRRRVGM 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGT----FSGGMKQRLGIAQALLHKPSLI 151
Cdd:PRK14271 106 LFQRPNPFPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAVKDRLSDspfrLSGGQQQLLCLARTLAVNPEVL 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 152 VMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:PRK14271 186 LLDEPTSALDPTTTEKIEEFIRSLADRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLF 250
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
35-204 |
3.64e-20 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 89.16 E-value: 3.64e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 35 GPNGAGKSTLIKVISDIINPNAGEVLLN---------GIKISKMKREIGYLPQYPNFFHWMTARETLTFmgqlsGLKKee 105
Cdd:PRK11144 31 GRSGAGKTSLINAISGLTRPQKGRIVLNgrvlfdaekGICLPPEKRRIGYVFQDARLFPHYKVRGNLRY-----GMAK-- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 106 lsKSIPKILEKVGLRGEE---NSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TT 180
Cdd:PRK11144 104 --SMVAQFDKIVALLGIEpllDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREinIP 181
|
170 180
....*....|....*....|....*..
gi 1261024142 181 ILLSTHILsdaEEI---CERFVIIKDG 204
Cdd:PRK11144 182 ILYVSHSL---DEIlrlADRVVVLEQG 205
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
2-218 |
3.67e-20 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 87.45 E-value: 3.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIaVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPN----AGEVLLNGIKISKMK---REIG 74
Cdd:PRK10418 4 QIELRNIALQAAQPL-VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAGvrqtAGRVLLDGKPVAPCAlrgRKIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYP----NFFHWMT--ARETLTFMGQLSGLKkeelskSIPKILEKVGLrgEENSKVGT-----FSGGMKQRLGIAQA 143
Cdd:PRK10418 83 TIMQNPrsafNPLHTMHthARETCLALGKPADDA------TLTAALEAVGL--ENAARVLKlypfeMSGGMLQRMMIALA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:PRK10418 155 LLCEAPFIIADEPTTDLDVVAQARILDLLESIvqKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNA 231
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
3-219 |
3.90e-20 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 90.46 E-value: 3.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGK--IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGI-----KISKMKREIGY 75
Cdd:PRK11176 342 IEFRNVTFTYPGKevPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHdlrdyTLASLRNQVAL 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYPNFFHWMTARE-TLTFMGQLSglkKEELSKS---------IPKIleKVGLR---GEENSkvgTFSGGMKQRLGIAQ 142
Cdd:PRK11176 422 VSQNVHLFNDTIANNiAYARTEQYS---REQIEEAarmayamdfINKM--DNGLDtviGENGV---LLSGGQRQRIAIAR 493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 143 ALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEIcerfVIIKDGTKIEDTTITELLQRN 219
Cdd:PRK11176 494 ALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLStieKADEI----LVVEDGEIVERGTHAELLAQN 569
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
2-204 |
5.76e-20 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 87.35 E-value: 5.76e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGYL 76
Cdd:PRK10253 7 RLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHyaskeVARRIGLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTAREtLTFMGQ------LSGLKKEElSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSL 150
Cdd:PRK10253 87 AQNATTPGDITVQE-LVARGRyphqplFTRWRKED-EEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAI 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 151 IVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSThILSDAEEICE---RFVIIKDG 204
Cdd:PRK10253 165 MLLDEPTTWLDISHQIDLLELLSELNREKGYTLAA-VLHDLNQACRyasHLIALREG 220
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
17-242 |
6.28e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 87.37 E-value: 6.28e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKI----------SKMKREIGYLPQYPNFFHWM 86
Cdd:PRK13645 26 ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpanlkkikevKRLRKEIGLVFQFPEYQLFQ 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 87 TARETLTFMGQLS-GLKKEELSKSIPKILEKVGLRgEENSKVGTF--SGGMKQRLGIAQALLHKPSLIVMDEPVSALDPI 163
Cdd:PRK13645 106 ETIEKDIAFGPVNlGENKQEAYKKVPELLKLVQLP-EDYVKRSPFelSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPK 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 164 GRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLqrnSENKLIIEITAKDQKWIDVVKK 241
Cdd:PRK13645 185 GEEDFINLFERLNKEykKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF---SNQELLTKIEIDPPKLYQLMYK 261
|
.
gi 1261024142 242 L 242
Cdd:PRK13645 262 L 262
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
15-221 |
6.62e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 87.38 E-value: 6.62e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 15 KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAG------EVLLNGIKISKMK---REIGYLPQYPNffHW 85
Cdd:PRK13634 20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGtvtigeRVITAGKKNKKLKplrKKVGIVFQFPE--HQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 86 M---TARETLTFMGQLSGLKKEELSKSIPKILEKVGLrGEENSKVGTF--SGGMKQRLGIAQALLHKPSLIVMDEPVSAL 160
Cdd:PRK13634 98 LfeeTVEKDICFGPMNFGVSEEDAKQKAREMIELVGL-PEELLARSPFelSGGQMRRVAIAGVLAMEPEVLVLDEPTAGL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 161 DPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQRNSE 221
Cdd:PRK13634 177 DPKGRKEMMEMFYKLhkEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPDE 239
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
3-205 |
6.89e-20 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 85.60 E-value: 6.89e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNF-----SMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGikiskmkrEIGYLP 77
Cdd:cd03250 1 ISVEDASFTWDSGEQETSFtlkdiNLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG--------SIAYVS 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPnffhW---MTARETLTFmgqLSGLKKEELSKSIP--------KILEK-----VGLRGEenskvgTFSGGMKQRLGIA 141
Cdd:cd03250 73 QEP----WiqnGTIRENILF---GKPFDEERYEKVIKacalepdlEILPDgdlteIGEKGI------NLSGGQKQRISLA 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 142 QALLHKPSLIVMDEPVSALDP-IGRREVLNLI-EEIKKDTTILLSTHILSDAEEiCERFVIIKDGT 205
Cdd:cd03250 140 RAVYSDADIYLLDDPLSAVDAhVGRHIFENCIlGLLLNNKTRILVTHQLQLLPH-ADQIVVLDNGR 204
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
19-219 |
8.08e-20 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 89.49 E-value: 8.08e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 19 NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYLPQypnffhwmtarETLT 93
Cdd:COG5265 375 KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTqaslrAAIGIVPQ-----------DTVL 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 94 F-------------------------MGQLsglkkEELSKSIPKILE-KVGLRGeenSKVgtfSGGMKQRLGIAQALLHK 147
Cdd:COG5265 444 FndtiayniaygrpdaseeeveaaarAAQI-----HDFIESLPDGYDtRVGERG---LKL---SGGEKQRVAIARTLLKN 512
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 148 PSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEIcerfVIIKDGTKIEDTTITELLQRN 219
Cdd:COG5265 513 PPILIFDEATSALDSRTERAIQAALREVARGRTTLVIAHRLStivDADEI----LVLEAGRIVERGTHAELLAQG 583
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
5-213 |
1.08e-19 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 86.48 E-value: 1.08e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFK-GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE--IGYLPQ--- 78
Cdd:PRK15056 9 VNDVTVTWRnGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKnlVAYVPQsee 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 ----YPNFFHWMTARETLTFMGQLSGLKKEElSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:PRK15056 89 vdwsFPVLVEDVVMMGRYGHMGWLRRAKKRD-RQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLD 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKdGTKI----EDTTIT 213
Cdd:PRK15056 168 EPFTGVDVKTEARIISLLRELRDEgKTMLVSTHNLGSVTEFCDYTVMVK-GTVLasgpTETTFT 230
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
3-214 |
1.16e-19 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 88.71 E-value: 1.16e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF----KGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLL----NGIKISK----- 68
Cdd:TIGR03269 280 IKVRNVSKRYisvdRGVVkAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrvgdEWVDMTKpgpdg 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 69 ---MKREIGYLPQYPNFFHWMTARETLTFMGQLSgLKKEELSKSIPKILEKVGLRGEENSKV-----GTFSGGMKQRLGI 140
Cdd:TIGR03269 360 rgrAKRYIGILHQEYDLYPHRTVLDNLTEAIGLE-LPDELARMKAVITLKMVGFDEEKAEEIldkypDELSEGERHRVAL 438
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 141 AQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGtKIEDTTITE 214
Cdd:TIGR03269 439 AQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEmeQTFIIVSHDMDFVLDVCDRAALMRDG-KIVKIGDPE 513
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
4-162 |
1.25e-19 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 85.91 E-value: 1.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK-----REIGYLPQ 78
Cdd:COG4604 3 EIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPsrelaKRLAILRQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTF------MGQLSGLKKEELSKSIpkilEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIV 152
Cdd:COG4604 83 ENHINSRLTVRELVAFgrfpysKGRLTAEDREIIDEAI----AYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVL 158
|
170
....*....|
gi 1261024142 153 MDEPVSALDP 162
Cdd:COG4604 159 LDEPLNNLDM 168
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
5-161 |
1.54e-19 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 87.39 E-value: 1.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIK---ISKMKREIGYLPQ--- 78
Cdd:PRK11000 6 LRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRmndVPPAERGVGMVFQsya 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 -YPNffhwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPV 157
Cdd:PRK11000 86 lYPH----LSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPL 161
|
....
gi 1261024142 158 SALD 161
Cdd:PRK11000 162 SNLD 165
|
|
| sufC |
TIGR01978 |
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ... |
3-186 |
3.45e-19 |
|
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 84.62 E-value: 3.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDiiNPN----AGEVLLNGIKISKMKRE------ 72
Cdd:TIGR01978 1 LKIKDLHVSVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAG--HPSyevtSGTILFKGQDLLELEPDerarag 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 73 IGYLPQYP---------NFFH-WMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGtFSGGMKQRLGIAQ 142
Cdd:TIGR01978 79 LFLAFQYPeeipgvsnlEFLRsALNARRSARGEEPLDLLDFEKLLKEKLALLDMDEEFLNRSVNEG-FSGGEKKRNEILQ 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1261024142 143 ALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIK-KDTTILLSTH 186
Cdd:TIGR01978 158 MALLEPKLAILDEIDSGLDIDALKIVAEGINRLRePDRSFLIITH 202
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
3-209 |
3.60e-19 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 87.47 E-value: 3.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF---KGKIAV-NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGE--------VLLNGIKISKMK 70
Cdd:PRK10535 5 LELKDIRRSYpsgEEQVEVlKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTyrvagqdvATLDADALAQLR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 RE-IGYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPS 149
Cdd:PRK10535 85 REhFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQ 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 150 LIVMDEPVSALDPIGRREVLNLIEEIK-KDTTILLSTH---ILSDAEEICErfviIKDGTKIED 209
Cdd:PRK10535 165 VILADEPTGALDSHSGEEVMAILHQLRdRGHTVIIVTHdpqVAAQAERVIE----IRDGEIVRN 224
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
15-208 |
3.74e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 85.27 E-value: 3.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 15 KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS---------KMKREIGYLPQYP--NFF 83
Cdd:PRK13641 20 KKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITpetgnknlkKLRKKVSLVFQFPeaQLF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 84 HwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVG-TFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDP 162
Cdd:PRK13641 100 E-NTVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSEDLISKSPfELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDP 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1261024142 163 IGRREVLNLIEEIKKDT-TILLSTHILSDAEEICERFVIIKDGTKIE 208
Cdd:PRK13641 179 EGRKEMMQLFKDYQKAGhTVILVTHNMDDVAEYADDVLVLEHGKLIK 225
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
17-216 |
5.26e-19 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 86.87 E-value: 5.26e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG----IKISKmkreiGYLPQypnffhwMTARETL 92
Cdd:PRK13545 39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGsaalIAISS-----GLNGQ-------LTGIENI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 93 TFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLI 172
Cdd:PRK13545 107 ELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDKM 186
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1261024142 173 EEIK-KDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELL 216
Cdd:PRK13545 187 NEFKeQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVV 231
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
1-207 |
6.02e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 84.80 E-value: 6.02e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKS------FKGKiAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKI---SKMK- 70
Cdd:PRK13649 1 MGINLQNVSYTyqagtpFEGR-ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLItstSKNKd 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 -----REIGYLPQYP--NFFHwMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVG-TFSGGMKQRLGIAQ 142
Cdd:PRK13649 80 ikqirKKVGLVFQFPesQLFE-ETVLKDVAFGPQNFGVSQEEAEALAREKLALVGISESLFEKNPfELSGGQMRRVAIAG 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 143 ALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICErFVIIKDGTKI 207
Cdd:PRK13649 159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSgMTIVLVTHLMDDVANYAD-FVYVLEKGKL 223
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
3-208 |
6.27e-19 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 84.21 E-value: 6.27e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEV--------LLNGIKISKMKR--- 71
Cdd:PRK11701 7 LSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVhyrmrdgqLRDLYALSEAERrrl 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 72 ---EIGYLPQYPnffhwmtaRETLTfMGQLSGlkkeelsKSIPKILEKVGLRGEEN---------SKV-----------G 128
Cdd:PRK11701 87 lrtEWGFVHQHP--------RDGLR-MQVSAG-------GNIGERLMAVGARHYGDiratagdwlERVeidaariddlpT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 129 TFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDT--TILLSTHILSDAEEICERFVIIKDGTK 206
Cdd:PRK11701 151 TFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELglAVVIVTHDLAVARLLAHRLLVMKQGRV 230
|
..
gi 1261024142 207 IE 208
Cdd:PRK11701 231 VE 232
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
3-184 |
7.17e-19 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 86.48 E-value: 7.17e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVllngiKISKmKREIGYLPQ--YP 80
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV-----KWSE-NANIGYYAQdhAY 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 81 NFFHWMTAREtltFMGQLSGLKKEELskSIPKILEKVGLRGEE-NSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSA 159
Cdd:PRK15064 394 DFENDLTLFD---WMSQWRQEGDDEQ--AVRGTLGRLLFSQDDiKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNH 468
|
170 180
....*....|....*....|....*..
gi 1261024142 160 LD--PIgrrEVLNLIEEIKKDTTILLS 184
Cdd:PRK15064 469 MDmeSI---ESLNMALEKYEGTLIFVS 492
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
3-243 |
1.10e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 84.52 E-value: 1.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGK-----IAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS---------- 67
Cdd:PRK13631 22 LRVKNLYCVFDEKqenelVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGdkknnhelit 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 68 -----------KMKREIGYLPQYPNFFHWMTARETLTFMGQLS-GLKKEELSKSIPKILEKVGLRGE--ENSKVGtFSGG 133
Cdd:PRK13631 102 npyskkiknfkELRRRVSMVFQFPEYQLFKDTIEKDIMFGPVAlGVKKSEAKKLAKFYLNKMGLDDSylERSPFG-LSGG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 134 MKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDT-TILLSTHILSDAEEICERFV------IIKDGTK 206
Cdd:PRK13631 181 QKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNkTVFVITHTMEHVLEVADEVIvmdkgkILKTGTP 260
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1261024142 207 IEDTTITELLQRNSENK-----LIIEITAKDQKWIDVVKKLP 243
Cdd:PRK13631 261 YEIFTDQHIINSTSIQVprviqVINDLIKKDPKYKKLYQKQP 302
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
3-186 |
1.21e-18 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 82.19 E-value: 1.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNA--GEVLLNGIKISKM------KREIG 74
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYEVteGEILFKGEDITDLppeeraRLGIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNffhwmtaretltfmgQLSGLKKEELsksipkilekvgLRgeeNSKVGtFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:cd03217 81 LAFQYPP---------------EIPGVKNADF------------LR---YVNEG-FSGGEKKRNEILQLLLLEPDLAILD 129
|
170 180 190
....*....|....*....|....*....|...
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIK-KDTTILLSTH 186
Cdd:cd03217 130 EPDSGLDIDALRLVAEVINKLReEGKSVLIITH 162
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
3-208 |
3.67e-18 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 84.37 E-value: 3.67e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF---KG--------KIAVNNFSMELQSGECVGLIGPNGAGKST----LIKVIsdiinPNAGEVLLNGIKIS 67
Cdd:PRK15134 276 LDVEQLQVAFpirKGilkrtvdhNVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEIWFDGQPLH 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 68 KM--------KREIGYLPQYPNffHWMTAR--------ETLTF-MGQLSGLKKEElskSIPKILEKVGLRGEENSKV-GT 129
Cdd:PRK15134 351 NLnrrqllpvRHRIQVVFQDPN--SSLNPRlnvlqiieEGLRVhQPTLSAAQREQ---QVIAVMEEVGLDPETRHRYpAE 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 130 FSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTI--LLSTHILSDAEEICERFVIIKDGTKI 207
Cdd:PRK15134 426 FSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLayLFISHDLHVVRALCHQVIVLRQGEVV 505
|
.
gi 1261024142 208 E 208
Cdd:PRK15134 506 E 506
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
2-208 |
4.33e-18 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 80.92 E-value: 4.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKI--AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIG 74
Cdd:cd03369 6 EIEVENLSVRYAPDLppVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTipledLRSSLT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHWmTARETLTFMGQLSglkKEELSKSIpKILEkvglrGEENskvgtFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:cd03369 86 IIPQDPTLFSG-TIRSNLDPFDEYS---DEEIYGAL-RVSE-----GGLN-----LSQGQRQLLCLARALLKRPRVLVLD 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 155 EPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIE 208
Cdd:cd03369 151 EATASIDYATDALIQKTIREEFTNSTILTIAHRLRTIID-YDKILVMDAGEVKE 203
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
25-186 |
5.50e-18 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 80.66 E-value: 5.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 25 LQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG--IKISKMKREIGYLPQYPNFFHWMTARETLTFMGQLSGLK 102
Cdd:PRK13543 34 VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGktATRGDRSRFMAYLGHLPGLKADLSTLENLHFLCGLHGRR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 103 KEELSKSIPKIlekVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIE-EIKKDTTI 181
Cdd:PRK13543 114 AKQMPGSALAI---VGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISaHLRGGGAA 190
|
....*
gi 1261024142 182 LLSTH 186
Cdd:PRK13543 191 LVTTH 195
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
3-214 |
1.81e-17 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 82.14 E-value: 1.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIInPNA---GEVLLNG-------IKISKMK-- 70
Cdd:NF040905 2 LEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVY-PHGsyeGEILFDGevcrfkdIRDSEALgi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 ----RE---IGYLPQYPNFF-----------HWmtaRETLTfmgqlsglKKEELsksipkiLEKVGLRGEENSKVGTFSG 132
Cdd:NF040905 81 viihQElalIPYLSIAENIFlgnerakrgviDW---NETNR--------RAREL-------LAKVGLDESPDTLVTDIGV 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 133 GMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLStHILSDAEEICERFVIIKDGTKIE-- 208
Cdd:NF040905 143 GKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQgiTSIIIS-HKLNEIRRVADSITVLRDGRTIEtl 221
|
....*....
gi 1261024142 209 ---DTTITE 214
Cdd:NF040905 222 dcrADEVTE 230
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
32-218 |
1.99e-17 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 80.44 E-value: 1.99e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 32 GLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKR-------EIGYLPQYPNFFHWMTARET-LTFMGQLSGLKK 103
Cdd:PRK13638 31 GLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRgllalrqQVATVFQDPEQQIFYTDIDSdIAFSLRNLGVPE 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 104 EELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI-KKDTTIL 182
Cdd:PRK13638 111 AEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRRIvAQGNHVI 190
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1261024142 183 LSTHIL------SDAEEICERFVIIKDGTKIEDTTITELLQR 218
Cdd:PRK13638 191 ISSHDIdliyeiSDAVYVLRQGQILTHGAPGEVFACTEAMEQ 232
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
4-186 |
2.14e-17 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 82.31 E-value: 2.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLnGIKIskmkrEIGYLPQYpnff 83
Cdd:PRK11147 321 EMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHC-GTKL-----EVAYFDQH---- 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 84 hwmtaRETL----TFMGQLSGLKKEelsksipkilekVGLRGEEN-----------------SKVGTFSGGMKQRLGIAQ 142
Cdd:PRK11147 391 -----RAELdpekTVMDNLAEGKQE------------VMVNGRPRhvlgylqdflfhpkramTPVKALSGGERNRLLLAR 453
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1261024142 143 ALLhKPS-LIVMDEPVSALDPigrrEVLNLIEEIKKD--TTILLSTH 186
Cdd:PRK11147 454 LFL-KPSnLLILDEPTNDLDV----ETLELLEELLDSyqGTVLLVSH 495
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
3-204 |
2.48e-17 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 77.86 E-value: 2.48e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTksfkGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK------MKREIGYL 76
Cdd:cd03215 5 LEVRGLS----VKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRrsprdaIRAGIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPN---FFHWMTARETLTfmgqlsglkkeelsksIPKILekvglrgeenskvgtfSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:cd03215 81 PEDRKregLVLDLSVAENIA----------------LSSLL----------------SGGNQQKVVLARWLARDPRVLIL 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 154 DEPVSALDPIGRREVLNLIEEIKKD-TTILLsthILSDAEEI---CERFVIIKDG 204
Cdd:cd03215 129 DEPTRGVDVGAKAEIYRLIRELADAgKAVLL---ISSELDELlglCDRILVMYEG 180
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
3-161 |
3.33e-17 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 81.78 E-value: 3.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFkgkiavNNFSM-----ELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNgIKISkmkreigYLP 77
Cdd:PRK13409 341 VEYPDLTKKL------GDFSLeveggEIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE-LKIS-------YKP 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QY--PNFFhwMTARETLTFMGQ--LSGLKKEELSK--SIPKILEKvglrgeensKVGTFSGGMKQRLGIAQALLHKPSLI 151
Cdd:PRK13409 407 QYikPDYD--GTVEDLLRSITDdlGSSYYKSEIIKplQLERLLDK---------NVKDLSGGELQRVAIAACLSRDADLY 475
|
170
....*....|
gi 1261024142 152 VMDEPVSALD 161
Cdd:PRK13409 476 LLDEPSAHLD 485
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
5-207 |
4.41e-17 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 77.69 E-value: 4.41e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNA---GEVLLNGIKISKMK----REIGYLP 77
Cdd:cd03233 10 SFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVsveGDIHYNGIPYKEFAekypGEIIYVS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QYPNFFHWMTARETLTFMGQLsglkkeelsksipkilekvglRGEENSKVgtFSGGMKQRLGIAQALLHKPSLIVMDEPV 157
Cdd:cd03233 90 EEDVHFPTLTVRETLDFALRC---------------------KGNEFVRG--ISGGERKRVSIAEALVSRASVLCWDNST 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 158 SALDPIgrrEVLNLIEEIKKDTTILLSTHILS---DAEEICERF---VIIKDGTKI 207
Cdd:cd03233 147 RGLDSS---TALEILKCIRTMADVLKTTTFVSlyqASDEIYDLFdkvLVLYEGRQI 199
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
3-174 |
6.38e-17 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 76.42 E-value: 6.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVT-KSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISD--------IINPNAGEVLlngikiskmkrei 73
Cdd:cd03223 1 IELENLSlATPDGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGlwpwgsgrIGMPEGEDLL------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 gYLPQYPnffhwmtaretltFMGQlsGLKKEELSKSIPKILekvglrgeenskvgtfSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:cd03223 68 -FLPQRP-------------YLPL--GTLREQLIYPWDDVL----------------SGGEQQRLAFARLLLHKPKFVFL 115
|
170 180
....*....|....*....|.
gi 1261024142 154 DEPVSALDPIGRREVLNLIEE 174
Cdd:cd03223 116 DEATSALDEESEDRLYQLLKE 136
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
3-218 |
1.16e-16 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 78.79 E-value: 1.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSF---KGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPN----AGEVLLNGIKISKMK---- 70
Cdd:COG4170 4 LDIRNLTIEIdtpQGRVkAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNwhvtADRFRWNGIDLLKLSprer 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 71 -----REIGYLPQYPN---------FFHWMTARETLTFMGQLSGLKKEELSKSIpKILEKVGLRGEE---NSKVGTFSGG 133
Cdd:COG4170 84 rkiigREIAMIFQEPSscldpsakiGDQLIEAIPSWTFKGKWWQRFKWRKKRAI-ELLHRVGIKDHKdimNSYPHELTEG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 134 MKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDTT 211
Cdd:COG4170 163 ECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQlqGTSILLISHDLESISQWADTITVLYCGQTVESGP 242
|
....*..
gi 1261024142 212 ITELLQR 218
Cdd:COG4170 243 TEQILKS 249
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
3-161 |
1.36e-16 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 79.83 E-value: 1.36e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEV-LLNGIKiskmkreIGYLPQYPn 81
Cdd:PRK10636 313 LKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIgLAKGIK-------LGYFAQHQ- 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 82 fFHWMTARETLtfMGQLSGLKKEELSKSIPKILEKVGLRGEENSKV-GTFSGGMKQRLGIAQALLHKPSLIVMDEPVSAL 160
Cdd:PRK10636 385 -LEFLRADESP--LQHLARLAPQELEQKLRDYLGGFGFQGDKVTEEtRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHL 461
|
.
gi 1261024142 161 D 161
Cdd:PRK10636 462 D 462
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
19-186 |
2.46e-16 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 75.36 E-value: 2.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 19 NNFSMELQSGECVGLIGPNGAGKSTLIKVISD--IINPNAGEVLLNGIKISK-MKREIGYLPQYPNFFHWMTARETLTFM 95
Cdd:cd03232 24 NNISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILINGRPLDKnFQRSTGYVEQQDVHSPNLTVREALRFS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 96 GQLSGLKKEElsksipkilekvglrgeenskvgtfsggmKQRLGIAQALLHKPSLIVMDEPVSALDPigrREVLNLIEEI 175
Cdd:cd03232 104 ALLRGLSVEQ-----------------------------RKRLTIGVELAAKPSILFLDEPTSGLDS---QAAYNIVRFL 151
|
170
....*....|....*
gi 1261024142 176 KK--DT--TILLSTH 186
Cdd:cd03232 152 KKlaDSgqAILCTIH 166
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
2-220 |
4.42e-16 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 76.43 E-value: 4.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFK--GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNaGEVLLNG-----IKISKMKREIG 74
Cdd:cd03289 2 QMTVKDLTAKYTegGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDGvswnsVPLQKWRKAFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQyPNFFHWMTARETLTFMGQLSglkkeelSKSIPKILEKVGLRGEENSKVG-----------TFSGGMKQRLGIAQA 143
Cdd:cd03289 81 VIPQ-KVFIFSGTFRKNLDPYGKWS-------DEEIWKVAEEVGLKSVIEQFPGqldfvlvdggcVLSHGHKQLMCLARS 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRNS 220
Cdd:cd03289 153 VLSKAKILLLDEPSAHLDPITYQVIRKTLKQAFADCTVILSEHRIEAMLE-CQRFLVIEENKVRQYDSIQKLLNEKS 228
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
3-216 |
5.76e-16 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 77.82 E-value: 5.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKG----KIAVNNFSMELQSGECVGLIGPNGAGKS-TLIKVISDIINPNA----GEVLLNGIKISKMKR-- 71
Cdd:PRK15134 6 LAIENLSVAFRQqqtvRTVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPVvypsGDIRFHGESLLHASEqt 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 72 -------EIGYLPQYPnffhwMTARETL-TFMGQLS-------GLKKEELSKSIPKILEKVGLRgEENSKVGTF----SG 132
Cdd:PRK15134 86 lrgvrgnKIAMIFQEP-----MVSLNPLhTLEKQLYevlslhrGMRREAARGEILNCLDRVGIR-QAAKRLTDYphqlSG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 133 GMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKK--DTTILLSTHILSDAEEICERFVIIKDGTKIEDT 210
Cdd:PRK15134 160 GERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQelNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQN 239
|
....*.
gi 1261024142 211 TITELL 216
Cdd:PRK15134 240 RAATLF 245
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
25-210 |
6.97e-16 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 75.20 E-value: 6.97e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 25 LQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE---------IGYLPQYPNFFHWMTARETLTFM 95
Cdd:PRK10584 33 VKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEaraklrakhVGFVFQSFMLIPTLNALENVELP 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 96 GQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI 175
Cdd:PRK10584 113 ALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSL 192
|
170 180 190
....*....|....*....|....*....|....*..
gi 1261024142 176 KKD--TTILLSTHILSDAEEiCERFVIIKDGTKIEDT 210
Cdd:PRK10584 193 NREhgTTLILVTHDLQLAAR-CDRRLRLVNGQLQEEA 228
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
2-161 |
8.45e-16 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 77.52 E-value: 8.45e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGkiavnnFSM-----ELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNgIKISkmkreigYL 76
Cdd:COG1245 341 LVEYPDLTKSYGG------FSLeveggEIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDED-LKIS-------YK 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETltfmgqLSGLKKEELSKSIPK--ILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:COG1245 407 PQYISPDYDGTVEEF------LRSANTDDFGSSYYKteIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLD 480
|
....*..
gi 1261024142 155 EPVSALD 161
Cdd:COG1245 481 EPSAHLD 487
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
15-186 |
8.94e-16 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 75.26 E-value: 8.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 15 KIAVNN----FSMELQSGECVGLIGPNGAGKSTLIKVISDIInPNAGEVLLNGIKISKMK-----REIGYLPQ--YPNFF 83
Cdd:COG4138 5 DVAVAGrlgpISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLSDWSaaelaRHRAYLSQqqSPPFA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 84 hwMTARETLTfMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLH-------KPSLIVMDEP 156
Cdd:COG4138 84 --MPVFQYLA-LHQPAGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwptinpEGQLLLLDEP 160
|
170 180 190
....*....|....*....|....*....|.
gi 1261024142 157 VSALDPIGRREVLNLIEEIK-KDTTILLSTH 186
Cdd:COG4138 161 MNSLDVAQQAALDRLLRELCqQGITVVMSSH 191
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
3-218 |
1.70e-15 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 76.38 E-value: 1.70e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVIS--DIINPNAGEVLLN----------------GI 64
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRgmDQYEPTSGRIIYHvalcekcgyverpskvGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 65 KISK-----MKREIGYLPQYPNFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGT---------- 129
Cdd:TIGR03269 81 PCPVcggtlEPEEVDFWNLSDKLRRRIRKRIAIMLQRTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVdliemvqlsh 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 130 --------FSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEE--IKKDTTILLSTHILSDAEEICERFV 199
Cdd:TIGR03269 161 rithiardLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEavKASGISMVLTSHWPEVIEDLSDKAI 240
|
250
....*....|....*....
gi 1261024142 200 IIKDGTKIEDTTITELLQR 218
Cdd:TIGR03269 241 WLENGEIKEEGTPDEVVAV 259
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
3-204 |
1.71e-15 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 76.21 E-value: 1.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTksfkGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG--IKISK----MKREIGYL 76
Cdd:COG1129 257 LEVEGLS----VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGkpVRIRSprdaIRAGIAYV 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQ-------YPNffhwMTARE--TLTFMGQLSG---LKKEELSKSIPKILEKVGLR-GEENSKVGTFSGGMKQRLGIAQA 143
Cdd:COG1129 333 PEdrkgeglVLD----LSIREniTLASLDRLSRgglLDRRRERALAEEYIKRLRIKtPSPEQPVGNLSGGNQQKVVLAKW 408
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 144 LLHKPSLIVMDEP-----VSAldpigRREVLNLIEEIKKD-TTILLsthILSDAEEI---CERFVIIKDG 204
Cdd:COG1129 409 LATDPKVLILDEPtrgidVGA-----KAEIYRLIRELAAEgKAVIV---ISSELPELlglSDRILVMREG 470
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
17-204 |
3.19e-15 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 74.08 E-value: 3.19e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGiKISKMKREIGYLPQypnffhwMTARETLTFMG 96
Cdd:PRK13546 39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG-EVSVIAISAGLSGQ-------LTGIENIEFKM 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 97 QLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIK 176
Cdd:PRK13546 111 LCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFK 190
|
170 180
....*....|....*....|....*....
gi 1261024142 177 -KDTTILLSTHILSDAEEICERFVIIKDG 204
Cdd:PRK13546 191 eQNKTIFFVSHNLGQVRQFCTKIAWIEGG 219
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
21-188 |
6.72e-15 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 72.66 E-value: 6.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 21 FSMELQSGECVGLIGPNGAGKSTLIKVISDIInPNAGEVLLNGIKIS-----KMKREIGYLPQY--PNF----FHWMTar 89
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGQPLEawsaaELARHRAYLSQQqtPPFampvFQYLT-- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 90 etltfMGQLSGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLH-KPS------LIVMDEPVSALDp 162
Cdd:PRK03695 92 -----LHQPDKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQvWPDinpagqLLLLDEPMNSLD- 165
|
170 180
....*....|....*....|....*...
gi 1261024142 163 IGRREVLN-LIEEI-KKDTTILLSTHIL 188
Cdd:PRK03695 166 VAQQAALDrLLSELcQQGIAVVMSSHDL 193
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
3-195 |
9.50e-15 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 71.52 E-value: 9.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK----MKREIGYLPQ 78
Cdd:PRK13540 2 LDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKdlctYQKQLCFVGH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLTFMGQLSGLKKEelsksIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVS 158
Cdd:PRK13540 82 RSGINPYLTLRENCLYDIHFSPGAVG-----ITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLV 156
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1261024142 159 ALDPIGRREVLNLIEE-IKKDTTILLSTHI-----LSDAEEIC 195
Cdd:PRK13540 157 ALDELSLLTIITKIQEhRAKGGAVLLTSHQdlplnKADYEEYH 199
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
2-186 |
1.07e-14 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 74.24 E-value: 1.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSF-KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREiGYLPQYP 80
Cdd:PRK10522 322 TLELRNVTFAYqDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPE-DYRKLFS 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 81 NFF--HWMtaretltFMGQLSGLKKEELSKSIPKILEKVGLRG---EENSKVGT--FSGGMKQRLGIAQALLHKPSLIVM 153
Cdd:PRK10522 401 AVFtdFHL-------FDQLLGPEGKPANPALVEKWLERLKMAHkleLEDGRISNlkLSKGQKKRLALLLALAEERDILLL 473
|
170 180 190
....*....|....*....|....*....|....*..
gi 1261024142 154 DEPVSALDPIGRR----EVLNLIEEIKKdtTILLSTH 186
Cdd:PRK10522 474 DEWAADQDPHFRRefyqVLLPLLQEMGK--TIFAISH 508
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
3-189 |
1.50e-14 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 73.82 E-value: 1.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEvllngIKISKMKReIGYLPQypnf 82
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGT-----IEIGETVK-LAYVDQ---- 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 fhwmtARETLTfmgqlsGLKK--EELSKSIPKIleKVGLR---------------GEENSKVGTFSGGMKQRLGIAQALL 145
Cdd:TIGR03719 393 -----SRDALD------PNKTvwEEISGGLDII--KLGKReipsrayvgrfnfkgSDQQKKVGQLSGGERNRVHLAKTLK 459
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 146 HKPSLIVMDEPVSALDPigrrEVLNLIEE-----------IKKDTTIL--LSTHILS 189
Cdd:TIGR03719 460 SGGNVLLLDEPTNDLDV----ETLRALEEallnfagcavvISHDRWFLdrIATHILA 512
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
3-218 |
1.66e-14 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 73.74 E-value: 1.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK---GKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREIGYLPQ 78
Cdd:PRK10261 13 LAVENLNIAFMqeqQKIaAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSRQVIELSE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPN--------------FFHWMTARETLTFMGQL--------SGLKKEELSKSIPKILEKVGLRgEENSKVGTF----SG 132
Cdd:PRK10261 93 QSAaqmrhvrgadmamiFQEPMTSLNPVFTVGEQiaesirlhQGASREEAMVEAKRMLDQVRIP-EAQTILSRYphqlSG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 133 GMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTT--ILLSTHILSDAEEICERFVIIKDGTKIEDT 210
Cdd:PRK10261 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSmgVIFITHDMGVVAEIADRVLVMYQGEAVETG 251
|
....*...
gi 1261024142 211 TITELLQR 218
Cdd:PRK10261 252 SVEQIFHA 259
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
2-161 |
3.88e-14 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 71.80 E-value: 3.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK---REIGYLP 77
Cdd:PRK11650 3 GLKLQAVRKSYDGKTqVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEpadRDIAMVF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 Q----YPnffHwMTARETLTFMGQLSGLKKEELSKSI---PKILEkvglrgeenskVGTF--------SGGMKQRLGIAQ 142
Cdd:PRK11650 83 QnyalYP---H-MSVRENMAYGLKIRGMPKAEIEERVaeaARILE-----------LEPLldrkprelSGGQRQRVAMGR 147
|
170
....*....|....*....
gi 1261024142 143 ALLHKPSLIVMDEPVSALD 161
Cdd:PRK11650 148 AIVREPAVFLFDEPLSNLD 166
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
19-161 |
3.98e-14 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 70.51 E-value: 3.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 19 NNFSMELQSG-----ECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISkmkreigYLPQYpnffhwMTARETLT 93
Cdd:cd03237 11 GEFTLEVEGGsisesEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS-------YKPQY------IKADYEGT 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 94 FMGQLSGLKKEELSKS--IPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:cd03237 78 VRDLLSSITKDFYTHPyfKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLD 147
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
2-220 |
4.26e-14 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 72.64 E-value: 4.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFK--GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNaGEVLLNGIK-----ISKMKREIG 74
Cdd:TIGR01271 1217 QMDVQGLTAKYTeaGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDGVSwnsvtLQTWRKAFG 1295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQyPNFFHWMTARETLTFMGQLSglkkeelSKSIPKILEKVGLRgeenSKVGTF---------------SGGMKQRLG 139
Cdd:TIGR01271 1296 VIPQ-KVFIFSGTFRKNLDPYEQWS-------DEEIWKVAEEVGLK----SVIEQFpdkldfvlvdggyvlSNGHKQLMC 1363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 140 IAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRN 219
Cdd:TIGR01271 1364 LARSILSKAKILLLDEPSAHLDPVTLQIIRKTLKQSFSNCTVILSEHRVEALLE-CQQFLVIEGSSVKQYDSIQKLLNET 1442
|
.
gi 1261024142 220 S 220
Cdd:TIGR01271 1443 S 1443
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
18-220 |
6.45e-14 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 72.32 E-value: 6.45e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 18 VNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGYLPQYPNFFHWmTARETL 92
Cdd:PLN03232 1252 LHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKfgltdLRRVLSIIPQSPVLFSG-TVRFNI 1330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 93 TFMGQ------LSGLKKEELSKSIPKilEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRR 166
Cdd:PLN03232 1331 DPFSEhndadlWEALERAHIKDVIDR--NPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRTDS 1408
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 167 EVLNLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQRNS 220
Cdd:PLN03232 1409 LIQRTIREEFKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRDT 1461
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
1-217 |
2.21e-13 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 70.13 E-value: 2.21e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKREigylpqyp 80
Cdd:PRK10789 314 LDVNIRQFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLD-------- 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 81 nffHWmtaRETLTFMGQLSGLKKEELSKSI--------PKILEKVG---------LRGEE--NSKVG----TFSGGMKQR 137
Cdd:PRK10789 386 ---SW---RSRLAVVSQTPFLFSDTVANNIalgrpdatQQEIEHVArlasvhddiLRLPQgyDTEVGergvMLSGGQKQR 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 138 LGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEIcerfVIIKDGTKIEDTTITE 214
Cdd:PRK10789 460 ISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQWGEGRTVIISAHRLSaltEASEI----LVMQHGHIAQRGNHDQ 535
|
...
gi 1261024142 215 LLQ 217
Cdd:PRK10789 536 LAQ 538
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
5-215 |
2.68e-13 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 69.76 E-value: 2.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKI----SKMKRE--IGYLPQ 78
Cdd:PRK10982 1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIdfksSKEALEngISMVHQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 79 YPNFFHWMTARETLtFMGQ--LSGL--KKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMD 154
Cdd:PRK10982 81 ELNLVLQRSVMDNM-WLGRypTKGMfvDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMD 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1261024142 155 EPVSALDpigRREVLNLIEEIKK----DTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:PRK10982 160 EPTSSLT---EKEVNHLFTIIRKlkerGCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLAGL 221
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
20-204 |
2.82e-13 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 69.69 E-value: 2.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 20 NFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMK------REIGYLP---QYPNFF-----HW 85
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALStaqrlaRGLVYLPedrQSSGLYldaplAW 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 86 MTARETLTFMGQLSGLKKEElsksipKILEK----VGLR-GEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSAL 160
Cdd:PRK15439 361 NVCALTHNRRGFWIKPAREN------AVLERyrraLNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGV 434
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1261024142 161 DPIGRREVLNLIEEIKKD-TTILLsthILSDAEEI---CERFVIIKDG 204
Cdd:PRK15439 435 DVSARNDIYQLIRSIAAQnVAVLF---ISSDLEEIeqmADRVLVMHQG 479
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
22-217 |
4.58e-13 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 69.77 E-value: 4.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 22 SMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM-----KREIGYLPQYPNFFHWmTARETLTFMG 96
Cdd:PLN03130 1259 SFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFglmdlRKVLGIIPQAPVLFSG-TVRFNLDPFN 1337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 97 QLS------GLKKEELSKSI---PKILEKVGLRGEENskvgtFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPigRRE 167
Cdd:PLN03130 1338 EHNdadlweSLERAHLKDVIrrnSLGLDAEVSEAGEN-----FSVGQRQLLSLARALLRRSKILVLDEATAAVDV--RTD 1410
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 168 VL--NLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIEDTTITELLQ 217
Cdd:PLN03130 1411 ALiqKTIREEFKSCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLLS 1461
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
28-161 |
6.82e-13 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 68.98 E-value: 6.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 28 GECVGLIGPNGAGKSTLIKVISDIINP---NAGEVLLNGIKI-SKMKREIGYLPQYPNFFHWMTARETLTF---MGQLSG 100
Cdd:TIGR00956 789 GTLTALMGASGAGKTTLLNVLAERVTTgviTGGDRLVNGRPLdSSFQRSIGYVQQQDLHLPTSTVRESLRFsayLRQPKS 868
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1261024142 101 LKKEELSKSIPKILEKVGLRGEENSKVGTFSGGM----KQRLGIAQALLHKPSLIV-MDEPVSALD 161
Cdd:TIGR00956 869 VSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGLnveqRKRLTIGVELVAKPKLLLfLDEPTSGLD 934
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
3-219 |
2.05e-12 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 65.82 E-value: 2.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVIS-----DIINpnaGEVLLNGIKISKMKRE----- 72
Cdd:CHL00131 8 LEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAghpayKILE---GDILFKGESILDLEPEerahl 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 73 -IGYLPQYP-------NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRG---EENSKVGtFSGGMKQRLGIA 141
Cdd:CHL00131 85 gIFLAFQYPieipgvsNADFLRLAYNSKRKFQGLPELDPLEFLEIINEKLKLVGMDPsflSRNVNEG-FSGGEKKRNEIL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 142 QALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIK-KDTTILLSTHILSDAEEICERFV-IIKDGTKIE--DTTITELLQ 217
Cdd:CHL00131 164 QMALLDSELAILDETDSGLDIDALKIIAEGINKLMtSENSIILITHYQRLLDYIKPDYVhVMQNGKIIKtgDAELAKELE 243
|
..
gi 1261024142 218 RN 219
Cdd:CHL00131 244 KK 245
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
4-204 |
2.40e-12 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 66.96 E-value: 2.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVIS-DIINPNAGEVLLNGIK------ISKMKREIGYL 76
Cdd:PRK10938 262 VLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITgDHPQGYSNDLTLFGRRrgsgetIWDIKKHIGYV 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PqypNFFHW-----MTARETLtfmgqLSGL---------KKEELSKSIPKILEKVGLRGE-ENSKVGTFSGGmKQRLG-I 140
Cdd:PRK10938 342 S---SSLHLdyrvsTSVRNVI-----LSGFfdsigiyqaVSDRQQKLAQQWLDILGIDKRtADAPFHSLSWG-QQRLAlI 412
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 141 AQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEE-ICERFVIIKDG 204
Cdd:PRK10938 413 VRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLisEGETQLLFVSHHAEDAPAcITHRLEFVPDG 479
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
3-216 |
2.63e-12 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 66.36 E-value: 2.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFK---GKI-AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPN----AGEVLLNGIKISKM----- 69
Cdd:PRK15093 4 LDIRNLTIEFKtsdGWVkAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNwrvtADRMRFDDIDLLRLsprer 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 70 KREIGYlpqypnffhwmtaRETLTFMGQLSGLKKEE-----LSKSIP--------------------KILEKVGLRgEEN 124
Cdd:PRK15093 84 RKLVGH-------------NVSMIFQEPQSCLDPSErvgrqLMQNIPgwtykgrwwqrfgwrkrraiELLHRVGIK-DHK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 125 SKVGTF----SGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERF 198
Cdd:PRK15093 150 DAMRSFpyelTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNnnTTILLISHDLQMLSQWADKI 229
|
250
....*....|....*...
gi 1261024142 199 VIIKDGTKIEDTTITELL 216
Cdd:PRK15093 230 NVLYCGQTVETAPSKELV 247
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
25-207 |
2.87e-12 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 67.06 E-value: 2.87e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 25 LQSGECVGLIGPNGAGKSTLIKVISDIIN----PNAGEVLLNGIKISKMKR----EIGYLPQYPNFFHWMTARETLTFMG 96
Cdd:TIGR00956 84 IKPGELTVVLGRPGSGCSTLLKTIASNTDgfhiGVEGVITYDGITPEEIKKhyrgDVVYNAETDVHFPHLTVGETLDFAA 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 97 QLS-------GLKKEELSKSIPK-ILEKVGLRGEENSKVGT-----FSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPI 163
Cdd:TIGR00956 164 RCKtpqnrpdGVSREEYAKHIADvYMATYGLSHTRNTKVGNdfvrgVSGGERKRVSIAEASLGGAKIQCWDNATRGLDSA 243
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1261024142 164 GRREVLNLIEEIKK--DTTILLSthILSDAEEICERF---VIIKDGTKI 207
Cdd:TIGR00956 244 TALEFIRALKTSANilDTTPLVA--IYQCSQDAYELFdkvIVLYEGYQI 290
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
3-161 |
3.26e-12 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 66.68 E-value: 3.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEvllngIKISKMKReIGYLPQypnf 82
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGT-----IKIGETVK-LAYVDQ---- 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 fhwmtARETLTfmgqlsgLKK---EELSKSIPKIleKVGLRgEENS----------------KVGTFSGGMKQRLGIAQA 143
Cdd:PRK11819 395 -----SRDALD-------PNKtvwEEISGGLDII--KVGNR-EIPSrayvgrfnfkggdqqkKVGVLSGGERNRLHLAKT 459
|
170
....*....|....*...
gi 1261024142 144 LLHKPSLIVMDEPVSALD 161
Cdd:PRK11819 460 LKQGGNVLLLDEPTNDLD 477
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
2-217 |
3.63e-12 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 66.89 E-value: 3.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKI--AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIG 74
Cdd:TIGR00957 1284 RVEFRNYCLRYREDLdlVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKiglhdLRFKIT 1363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHWmTARETLTFMGQ-----------LSGLKkeELSKSIPKILEKVGLRGEENSKVgtfsgGMKQRLGIAQA 143
Cdd:TIGR00957 1364 IIPQDPVLFSG-SLRMNLDPFSQysdeevwwaleLAHLK--TFVSALPDKLDHECAEGGENLSV-----GQRQLVCLARA 1435
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 144 LLHKPSLIVMDEPVSALDpigrREVLNLIEEIKK----DTTILLSTHILSDAEEIcERFVIIKDGTKIEDTTITELLQ 217
Cdd:TIGR00957 1436 LLRKTKILVLDEATAAVD----LETDNLIQSTIRtqfeDCTVLTIAHRLNTIMDY-TRVIVLDKGEVAEFGAPSNLLQ 1508
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
15-231 |
3.64e-12 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 66.92 E-value: 3.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 15 KIAVNNFSMELQSGECVGLIGPNGAGKSTLIK-VISDIINPNAGEVLLNGikiskmkrEIGYLPQYPNFFHwMTARETLT 93
Cdd:PLN03232 630 KPTLSDINLEIPVGSLVAIVGGTGEGKTSLISaMLGELSHAETSSVVIRG--------SVAYVPQVSWIFN-ATVRENIL 700
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 94 FMgqlSGLKKEELSKSIPKILEKVGLR---GEENSKVG----TFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRR 166
Cdd:PLN03232 701 FG---SDFESERYWRAIDVTALQHDLDllpGRDLTEIGergvNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAH 777
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 167 EVLN--LIEEIKKDTTILLST--HILSdaeeICERFVIIKDGTKIEDTTITELLQRNSENKLIIEITAK 231
Cdd:PLN03232 778 QVFDscMKDELKGKTRVLVTNqlHFLP----LMDRIILVSEGMIKEEGTFAELSKSGSLFKKLMENAGK 842
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
14-162 |
4.08e-12 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 66.31 E-value: 4.08e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 14 GKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVIsdiinpnaGEV--LLNGIKISKMKREIGYLPQYPnFFHWMTARET 91
Cdd:TIGR00954 464 GDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRIL--------GELwpVYGGRLTKPAKGKLFYVPQRP-YMTLGTLRDQ 534
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 92 LTFMGQLSGLKKEELS-KSIPKILEKVGL-----RGEENSKVGTF----SGGMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:TIGR00954 535 IIYPDSSEDMKRRGLSdKDLEQILDNVQLthileREGGWSAVQDWmdvlSGGEKQRIAMARLFYHKPQFAILDECTSAVS 614
|
.
gi 1261024142 162 P 162
Cdd:TIGR00954 615 V 615
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
3-215 |
4.74e-12 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 66.20 E-value: 4.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVT-KSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE------IGY 75
Cdd:COG3845 258 LEVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRerrrlgVAY 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQ-------YPNffhwMTARETLTfmgqLSGLKKEELSKSI-----------PKILEKVGLR-GEENSKVGTFSGGMKQ 136
Cdd:COG3845 338 IPEdrlgrglVPD----MSVAENLI----LGRYRRPPFSRGGfldrkairafaEELIEEFDVRtPGPDTPARSLSGGNQQ 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 137 RLGIAQALLHKPSLIVMDEPVSALDpIG-----RREvlnLIEEIKKDTTILLsthILSDAEEI---CERFVIIKDG---- 204
Cdd:COG3845 410 KVILARELSRDPKLLIAAQPTRGLD-VGaiefiHQR---LLELRDAGAAVLL---ISEDLDEIlalSDRIAVMYEGrivg 482
|
250
....*....|..
gi 1261024142 205 -TKIEDTTITEL 215
Cdd:COG3845 483 eVPAAEATREEI 494
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
17-215 |
1.37e-11 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 63.99 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIIN-PN---AGEVLLNG---IKIS-KMKREI--------------G 74
Cdd:PRK11022 22 AVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDyPGrvmAEKLEFNGqdlQRISeKERRNLvgaevamifqdpmtS 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYPNFFHWMTARETltfmgQLSGLKKEELSKSIpKILEKVGLRGEEnSKVGTF----SGGMKQRLGIAQALLHKPSL 150
Cdd:PRK11022 102 LNPCYTVGFQIMEAIKV-----HQGGNKKTRRQRAI-DLLNQVGIPDPA-SRLDVYphqlSGGMSQRVMIAMAIACRPKL 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 151 IVMDEPVSALDPIGRREVLNLIEEI--KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:PRK11022 175 LIADEPTTALDVTIQAQIIELLLELqqKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDI 241
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
5-161 |
2.02e-11 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 64.19 E-value: 2.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFKGKIAV-NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLN-GIKiskmkreIGYLPQYPNF 82
Cdd:TIGR03719 7 MNRVSKVVPPKKEIlKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQpGIK-------VGYLPQEPQL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 FHWMTARE-----------TLTFMGQLSGLKKEE------LSKSIPKILEKV-----------------GLR-GEENSKV 127
Cdd:TIGR03719 80 DPTKTVREnveegvaeikdALDRFNEISAKYAEPdadfdkLAAEQAELQEIIdaadawdldsqleiamdALRcPPWDADV 159
|
170 180 190
....*....|....*....|....*....|....
gi 1261024142 128 GTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:TIGR03719 160 TKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLD 193
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
25-188 |
2.33e-11 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 64.04 E-value: 2.33e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 25 LQSGECVGLIGPNGAGKSTLIKVISDIINPNAG---------EVL--LNGI-------KISKMKREIGYLPQY----PNF 82
Cdd:COG1245 96 PKKGKVTGILGPNGIGKSTALKILSGELKPNLGdydeepswdEVLkrFRGTelqdyfkKLANGEIKVAHKPQYvdliPKV 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 FHwMTARETltfmgqlsgLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDP 162
Cdd:COG1245 176 FK-GTVREL---------LEKVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDI 245
|
170 180
....*....|....*....|....*..
gi 1261024142 163 IGRREVLNLIEEI-KKDTTILLSTHIL 188
Cdd:COG1245 246 YQRLNVARLIRELaEEGKYVLVVEHDL 272
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
25-188 |
2.37e-11 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 64.06 E-value: 2.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 25 LQSGECVGLIGPNGAGKSTLIKVISDIINPN-----------------AGEVLLNGI-KISKMKREIGYLPQY----PNF 82
Cdd:PRK13409 96 PKEGKVTGILGPNGIGKTTAVKILSGELIPNlgdyeeepswdevlkrfRGTELQNYFkKLYNGEIKVVHKPQYvdliPKV 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 83 FHWmTARETltfmgqlsgLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDp 162
Cdd:PRK13409 176 FKG-KVREL---------LKKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD- 244
|
170 180
....*....|....*....|....*..
gi 1261024142 163 IGRR-EVLNLIEEIKKDTTILLSTHIL 188
Cdd:PRK13409 245 IRQRlNVARLIRELAEGKYVLVVEHDL 271
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
4-204 |
3.78e-11 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 63.26 E-value: 3.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 4 EIRNVTKSFKGKiaVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS------KMKREIGYLP 77
Cdd:PRK09700 267 EVRNVTSRDRKK--VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISprspldAVKKGMAYIT 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QY---PNFFHWMTARETLTFMGQL--SGLK--------KEELsKSIPKILEKVGLRGEE-NSKVGTFSGGMKQRLGIAQA 143
Cdd:PRK09700 345 ESrrdNGFFPNFSIAQNMAISRSLkdGGYKgamglfheVDEQ-RTAENQRELLALKCHSvNQNITELSGGNQQKVLISKW 423
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 144 LLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD-TTILLSTHILSDAEEICERFVIIKDG 204
Cdd:PRK09700 424 LCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDgKVILMVSSELPEIITVCDRIAVFCEG 485
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
26-189 |
6.31e-11 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 61.61 E-value: 6.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 26 QSGECVGLIGPNGAGKSTLIKVISDIINPNAG---------EVL-----------LNGIKISKMK--REIGYLPQYPNFF 83
Cdd:cd03236 24 REGQVLGLVGPNGIGKSTALKILAGKLKPNLGkfddppdwdEILdefrgselqnyFTKLLEGDVKviVKPQYVDLIPKAV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 84 HWmTARETLTfmgqlsglKKEELSKsIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPI 163
Cdd:cd03236 104 KG-KVGELLK--------KKDERGK-LDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIK 173
|
170 180
....*....|....*....|....*..
gi 1261024142 164 GRREVLNLIEEIKKDT-TILLSTHILS 189
Cdd:cd03236 174 QRLNAARLIRELAEDDnYVLVVEHDLA 200
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
18-219 |
7.96e-11 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 62.66 E-value: 7.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 18 VNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVllngikisKMKREIGYLPQYPnffhWM---TARETLTF 94
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHV--------HMKGSVAYVPQQA----WIqndSLRENILF 721
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 95 MGQLSGLKKEELSKSIPKILEKVGLRGEENSKVG----TFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDP-IGRREVL 169
Cdd:TIGR00957 722 GKALNEKYYQQVLEACALLPDLEILPSGDRTEIGekgvNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAhVGKHIFE 801
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 170 NLI--EEIKKDTTILLSTHILSDAEEIceRFVIIKDGTKI-EDTTITELLQRN 219
Cdd:TIGR00957 802 HVIgpEGVLKNKTRILVTHGISYLPQV--DVIIVMSGGKIsEMGSYQELLQRD 852
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
13-217 |
2.46e-10 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 59.84 E-value: 2.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 13 KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVIS-DIINPNA-------GEVLLNG-----IKISKMKREIGYLPQY 79
Cdd:PRK13547 12 RHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAgDLTGGGAprgarvtGDVTLNGeplaaIDAPRLARLRAVLPQA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 80 PNFFHWMTAREtLTFMGQL-----SGLKKEELSKSIPKILEKVGLRGEENSKVGTFSGGMKQRLGIAQAL--LHK----- 147
Cdd:PRK13547 92 AQPAFAFSARE-IVLLGRYpharrAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLaqLWPphdaa 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1261024142 148 --PSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:PRK13547 171 qpPRYLLLDEPTAALDLAHQHRLLDTVRRLARDwnLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVLT 244
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
20-215 |
4.92e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 60.52 E-value: 4.92e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 20 NFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNA-GEVLLNGikiskmkrEIGYLPQYPNFFHwMTARETLTFMGQL 98
Cdd:PLN03130 635 NINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPPRSdASVVIRG--------TVAYVPQVSWIFN-ATVRDNILFGSPF 705
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 99 SGLKKEelsksipKILEKVGLR-------GEENSKVG----TFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRRE 167
Cdd:PLN03130 706 DPERYE-------RAIDVTALQhdldllpGGDLTEIGergvNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQ 778
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 168 VLN--LIEEIKKDTTILLST--HILSDAEEIcerfVIIKDGTKIEDTTITEL 215
Cdd:PLN03130 779 VFDkcIKDELRGKTRVLVTNqlHFLSQVDRI----ILVHEGMIKEEGTYEEL 826
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-219 |
5.68e-10 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 59.73 E-value: 5.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSF-KGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK-----MKREIGY 75
Cdd:PRK10790 340 RIDIDNVSFAYrDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSlshsvLRQGVAM 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQYP-----NFFHWMT------------ARETLtfmgQLSglkkeELSKSIPKILEKvgLRGEENSkvgTFSGGMKQRL 138
Cdd:PRK10790 420 VQQDPvvladTFLANVTlgrdiseeqvwqALETV----QLA-----ELARSLPDGLYT--PLGEQGN---NLSVGQKQLL 485
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 139 GIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKDTTILLSTHILS---DAEEIcerfVIIKDGTKIEDTTITEL 215
Cdd:PRK10790 486 ALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREHTTLVVIAHRLStivEADTI----LVLHRGQAVEQGTHQQL 561
|
....
gi 1261024142 216 LQRN 219
Cdd:PRK10790 562 LAAQ 565
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
22-168 |
2.06e-09 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 58.64 E-value: 2.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 22 SMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKIS-----KMKREIGYLPQYPNFFHWMTARETLTFMg 96
Cdd:PTZ00243 1330 SFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGayglrELRRQFSMIPQDPVLFDGTVRQNVDPFL- 1408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 97 qlsglkkEELSKSIPKILEKVGLRGEENSKVG-----------TFSGGMKQRLGIAQALLHKPS-LIVMDEPVSALDPIG 164
Cdd:PTZ00243 1409 -------EASSAEVWAALELVGLRERVASESEgidsrvleggsNYSVGQRQLMCMARALLKKGSgFILMDEATANIDPAL 1481
|
....
gi 1261024142 165 RREV 168
Cdd:PTZ00243 1482 DRQI 1485
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
24-201 |
3.44e-09 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 55.27 E-value: 3.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 24 ELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISkmkreigYLPQYPNffhwmtaretltfmgqlsglkk 103
Cdd:cd03222 21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPV-------YKPQYID---------------------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 104 eelsksipkilekvglrgeenskvgtFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGR----REVLNLIEEIKKdt 179
Cdd:cd03222 72 --------------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRlnaaRAIRRLSEEGKK-- 123
|
170 180
....*....|....*....|..
gi 1261024142 180 TILLSTHILSDAEEICERFVII 201
Cdd:cd03222 124 TALVVEHDLAVLDYLSDRIHVF 145
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
19-186 |
5.28e-09 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 55.35 E-value: 5.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 19 NNFSMELQSGECVGLIGPNGAGKSTLIKVISDII--NPNAGEVLLNGIKISKMKREIGYLPQYPNFfhwMTARETLTFMG 96
Cdd:COG2401 47 RDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPDNQFGREASLIDAIGRKGDF---KDAVELLNAVG 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 97 qlsglkkeeLSksipkilEKVGLRgeenSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDP-IGRREVLNLIEEI 175
Cdd:COG2401 124 ---------LS-------DAVLWL----RRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRqTAKRVARNLQKLA 183
|
170
....*....|..
gi 1261024142 176 KK-DTTILLSTH 186
Cdd:COG2401 184 RRaGITLVVATH 195
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
18-186 |
5.59e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 57.35 E-value: 5.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 18 VNNFSMELQSGEcvgligpngAGKSTLIKvisdiinpNAGEVLLNGIKI-----SKMKREIGYLPQYPNFFHwMTARETL 92
Cdd:PTZ00265 1255 VNEFSLTKEGGS---------GEDSTVFK--------NSGKILLDGVDIcdynlKDLRNLFSIVSQEPMLFN-MSIYENI 1316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 93 TFMGQ---LSGLKKEELSKSIPKILEKvgLRGEENSKVGTF----SGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGR 165
Cdd:PTZ00265 1317 KFGKEdatREDVKRACKFAAIDEFIES--LPNKYDTNVGPYgkslSGGQKQRIAIARALLREPKILLLDEATSSLDSNSE 1394
|
170 180
....*....|....*....|...
gi 1261024142 166 REVLNLIEEIKK--DTTILLSTH 186
Cdd:PTZ00265 1395 KLIEKTIVDIKDkaDKTIITIAH 1417
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
2-185 |
5.92e-09 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 56.55 E-value: 5.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSfkgkiAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISK------MKREIGY 75
Cdd:PRK10762 257 RLKVDNLSGP-----GVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTrspqdgLANGIVY 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 76 LPQ---YPNFFHWMTARE--TLTFMGQLS----GLKKEELSKSIPKILEKVGLRG-EENSKVGTFSGGMKQRLGIAQALL 145
Cdd:PRK10762 332 ISEdrkRDGLVLGMSVKEnmSLTALRYFSraggSLKHADEQQAVSDFIRLFNIKTpSMEQAIGLLSGGNQQKVAIARGLM 411
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1261024142 146 HKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLST 185
Cdd:PRK10762 412 TRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEglSIILVSS 453
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
20-194 |
1.07e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 56.46 E-value: 1.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 20 NFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGikiskmkrEIGYLPQYPnffhWM---TARETLTF-- 94
Cdd:TIGR01271 444 NISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSG--------RISFSPQTS----WImpgTIKDNIIFgl 511
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 95 ----MGQLSGLKKEELSKSIPKILEKvglrgeENSKVG----TFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRR 166
Cdd:TIGR01271 512 sydeYRYTSVIKACQLEEDIALFPEK------DKTVLGeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHLDVVTEK 585
|
170 180 190
....*....|....*....|....*....|..
gi 1261024142 167 EVLN--LIEEIKKDTTILLSTHI--LSDAEEI 194
Cdd:TIGR01271 586 EIFEscLCKLMSNKTRILVTSKLehLKKADKI 617
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
25-161 |
1.27e-08 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 55.73 E-value: 1.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 25 LQSGECVGLIGPNGAGKSTLIKVIsdiinpnAGEVLL--------NGIKISKMKR-------------------EIG-YL 76
Cdd:PRK11147 26 IEDNERVCLVGRNGAGKSTLMKIL-------NGEVLLddgriiyeQDLIVARLQQdpprnvegtvydfvaegieEQAeYL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 77 PQYPNFFHWMTARETLTFMGQLSGLKKE-------ELSKSIPKILEKVGLRGEenSKVGTFSGGMKQRLGIAQALLHKPS 149
Cdd:PRK11147 99 KRYHDISHLVETDPSEKNLNELAKLQEQldhhnlwQLENRINEVLAQLGLDPD--AALSSLSGGWLRKAALGRALVSNPD 176
|
170
....*....|..
gi 1261024142 150 LIVMDEPVSALD 161
Cdd:PRK11147 177 VLLLDEPTNHLD 188
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
6-161 |
1.33e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 55.51 E-value: 1.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 6 RNVTKSFKGKIAV-NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGE-VLLNGIKiskmkreIGYLPQYPNFF 83
Cdd:PRK11819 10 NRVSKVVPPKKQIlKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEaRPAPGIK-------VGYLPQEPQLD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 84 HWMTARETL-TFMGQLSGLKKE--ELSK--SIP-----KILEKVG------------------------LR-GEENSKVG 128
Cdd:PRK11819 83 PEKTVRENVeEGVAEVKAALDRfnEIYAayAEPdadfdALAAEQGelqeiidaadawdldsqleiamdaLRcPPWDAKVT 162
|
170 180 190
....*....|....*....|....*....|...
gi 1261024142 129 TFSGGMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:PRK11819 163 KLSGGERRRVALCRLLLEKPDMLLLDEPTNHLD 195
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
25-220 |
1.91e-08 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 54.14 E-value: 1.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 25 LQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM-----KREIGYLPQYPNFF----------HWMTAR 89
Cdd:cd03288 44 IKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLplhtlRSRLSIILQDPILFsgsirfnldpECKCTD 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 90 ETLTFMGQLSGLKKeeLSKSIPKILEKVGLRGEENskvgtFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVL 169
Cdd:cd03288 124 DRLWEALEIAQLKN--MVKSLPGGLDAVVTEGGEN-----FSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQ 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 170 NLIEEIKKDTTILLSTHILSDAEEiCERFVIIKDGTKIE-DTTITELLQRNS 220
Cdd:cd03288 197 KVVMTAFADRTVVTIAHRVSTILD-ADLVLVLSRGILVEcDTPENLLAQEDG 247
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
20-161 |
5.75e-08 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 53.71 E-value: 5.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 20 NFSMELQSGecVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGikiskmKREIGYLPQYPNFFHWMTARETLTFMGQLS 99
Cdd:PLN03073 529 NFGIDLDSR--IAMVGPNGIGKSTILKLISGELQPSSGTVFRSA------KVRMAVFSQHHVDGLDLSSNPLLYMMRCFP 600
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 100 GLKKEELSKSipkiLEKVGLRGE-ENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:PLN03073 601 GVPEQKLRAH----LGSFGVTGNlALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD 659
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
5-161 |
6.10e-08 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 54.08 E-value: 6.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 5 IRNVTKSFKgkiavnnfsmelqSGECVGLIGPNGAGKSTLIKVISdiiNPNAGEVLLNGIKIS-------KMKREIGYLP 77
Cdd:PLN03140 896 LREVTGAFR-------------PGVLTALMGVSGAGKTTLMDVLA---GRKTGGYIEGDIRISgfpkkqeTFARISGYCE 959
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 78 QypNFFH--WMTARETLTFMGQLSGLK---KEELSKSIPKILEKVGLRGEENSKVGT-----FSGGMKQRLGIAQALLHK 147
Cdd:PLN03140 960 Q--NDIHspQVTVRESLIYSAFLRLPKevsKEEKMMFVDEVMELVELDNLKDAIVGLpgvtgLSTEQRKRLTIAVELVAN 1037
|
170
....*....|....
gi 1261024142 148 PSLIVMDEPVSALD 161
Cdd:PLN03140 1038 PSIIFMDEPTSGLD 1051
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
35-189 |
9.29e-08 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 51.41 E-value: 9.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 35 GPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKM-KREIGYLPQYPNFFHWMTARETLTFMGQLSglkkeELSKSIPKI 113
Cdd:PRK13541 33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIaKPYCTYIGHNLGLKLEMTVFENLKFWSEIY-----NSAETLYAA 107
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 114 LEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIeEIKKDT--TILLSTHILS 189
Cdd:PRK13541 108 IHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNLI-VMKANSggIVLLSSHLES 184
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
3-161 |
1.08e-07 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 52.86 E-value: 1.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKsfkgkIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGI-KISKMKREIGYLPQYPN 81
Cdd:PRK10636 7 LQIRRGVR-----VLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNwQLAWVNQETPALPQPAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 82 FFHWMTARE-------------------TLTFMGQLSGLKKEELSKSIPKILEKVGLRGEE-NSKVGTFSGGMKQRLGIA 141
Cdd:PRK10636 82 EYVIDGDREyrqleaqlhdanerndghaIATIHGKLDAIDAWTIRSRAASLLHGLGFSNEQlERPVSDFSGGWRMRLNLA 161
|
170 180
....*....|....*....|
gi 1261024142 142 QALLHKPSLIVMDEPVSALD 161
Cdd:PRK10636 162 QALICRSDLLLLDEPTNHLD 181
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
17-194 |
1.90e-07 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 50.01 E-value: 1.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 17 AVNNFSMELQSGECVGLIGPNGAGKSTLikvisdiinpnagevLLNGIKISKMKREIGYLPQYPnffhwmtaRETLTFMG 96
Cdd:cd03238 10 NLQNLDVSIPLNVLVVVTGVSGSGKSTL---------------VNEGLYASGKARLISFLPKFS--------RNKLIFID 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 97 QLSGLkkeelsksIPKILEKVGLrgeeNSKVGTFSGGMKQRLGIAQALL--HKPSLIVMDEPVSALDPIGRREVLNLIEE 174
Cdd:cd03238 67 QLQFL--------IDVGLGYLTL----GQKLSTLSGGELQRVKLASELFsePPGTLFILDEPSTGLHQQDINQLLEVIKG 134
|
170 180
....*....|....*....|....
gi 1261024142 175 I--KKDTTILLSTH--ILSDAEEI 194
Cdd:cd03238 135 LidLGNTVILIEHNldVLSSADWI 158
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
18-205 |
2.19e-07 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 50.79 E-value: 2.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 18 VNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKISKMKRE---------IGYLPQYPnffhWM-- 86
Cdd:cd03290 17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEatrsrnrysVAYAAQKP----WLln 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 87 -TARETLTFMGQLSGLKKEELSKSI---PKI-LEKVGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSAL- 160
Cdd:cd03290 93 aTVEENITFGSPFNKQRYKAVTDACslqPDIdLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALd 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 161 ----DPIGRREVLNLIEEIKKdtTILLSTH---ILSDAEEIcerfVIIKDGT 205
Cdd:cd03290 173 ihlsDHLMQEGILKFLQDDKR--TLVLVTHklqYLPHADWI----IAMKDGS 218
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
27-202 |
2.83e-07 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 49.28 E-value: 2.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 27 SGECVGLIGPNGAGKSTLIKVISdiinpnagevLLNGIKISKMKREIGYLPQYPnffhwmTARETLTFMGQLSGLkkeel 106
Cdd:cd03227 20 EGSLTIITGPNGSGKSTILDAIG----------LALGGAQSATRRRSGVKAGCI------VAAVSAELIFTRLQL----- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 107 sksipkilekvglrgeenskvgtfSGGMKQRLGIAQAL---LHKP-SLIVMDEPVSALDPIGRREVLNLIEEI-KKDTTI 181
Cdd:cd03227 79 ------------------------SGGEKELSALALILalaSLKPrPLYILDEIDRGLDPRDGQALAEAILEHlVKGAQV 134
|
170 180
....*....|....*....|.
gi 1261024142 182 LLSTHiLSDAEEICERFVIIK 202
Cdd:cd03227 135 IVITH-LPELAELADKLIHIK 154
|
|
| DUF4162 |
pfam13732 |
Domain of unknown function (DUF4162); This domain is found at the C-terminus of bacterial ABC ... |
211-298 |
3.89e-07 |
|
Domain of unknown function (DUF4162); This domain is found at the C-terminus of bacterial ABC transporter proteins. The function is not known.
Pssm-ID: 463971 [Multi-domain] Cd Length: 82 Bit Score: 46.82 E-value: 3.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 211 TITELLQRNSENKLIIEITAkdqkwIDVVKKLPYVKDVEVIGLKVKVKVESIEVNKNLLlqNALEHKVDIIKFEVSNDTL 290
Cdd:pfam13732 2 TLEEIKRSYGRNRIEVETAD-----AEELLELPGVEEVEEEGGGLELKLEDEEAANELL--AALLSGGEIRSFEEEEPSL 74
|
....*...
gi 1261024142 291 EEIFLKLV 298
Cdd:pfam13732 75 NDIFIEKV 82
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
20-215 |
6.94e-07 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 49.86 E-value: 6.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 20 NFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGikiskmkrEIGYLPQypnfFHWM---TARETLTF-- 94
Cdd:cd03291 55 NINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSG--------RISFSSQ----FSWImpgTIKENIIFgv 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 95 ----MGQLSGLKKEELSKSIPKILEKvglrgeENSKVG----TFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRR 166
Cdd:cd03291 123 sydeYRYKSVVKACQLEEDITKFPEK------DNTVLGeggiTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEK 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 167 EVLN--LIEEIKKDTTILLSTHI--LSDAEEIcerfVIIKDGTKIEDTTITEL 215
Cdd:cd03291 197 EIFEscVCKLMANKTRILVTSKMehLKKADKI----LILHEGSSYFYGTFSEL 245
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
3-217 |
1.21e-06 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 49.73 E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKsfKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNGIKI---------------- 66
Cdd:PRK10982 251 LEVRNLTS--LRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKInnhnaneainhgfalv 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 67 SKMKREIGYLPQYPNFFHWMTArETLTFMGQLSGLKKEELSKSIPKILEKVGLRG-EENSKVGTFSGGMKQRLGIAQALL 145
Cdd:PRK10982 329 TEERRSTGIYAYLDIGFNSLIS-NIRNYKNKVGLLDNSRMKSDTQWVIDSMRVKTpGHRTQIGSLSGGNQQKVIIGRWLL 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1261024142 146 HKPSLIVMDEPVSALDPIGRREVLNLIEEI-KKDTTILLSTHILSDAEEICERFVIIKDG-----TKIEDTTITELLQ 217
Cdd:PRK10982 408 TQPEILMLDEPTRGIDVGAKFEIYQLIAELaKKDKGIIIISSEMPELLGITDRILVMSNGlvagiVDTKTTTQNEILR 485
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
2-223 |
1.71e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 49.64 E-value: 1.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVTKSFKGKIAV---NNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG------IKISKMKRE 72
Cdd:PTZ00265 382 KIQFKNVRFHYDTRKDVeiyKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDshnlkdINLKWWRSK 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 73 IGYLPQYPNFF------------------------------------------------------HWMTARETLTFMGQL 98
Cdd:PTZ00265 462 IGVVSQDPLLFsnsiknnikyslyslkdlealsnyynedgndsqenknkrnscrakcagdlndmsNTTDSNELIEMRKNY 541
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 99 SGLKKEELSKSIPKIL----------EKVGLRGEENSKVgtfSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREV 168
Cdd:PTZ00265 542 QTIKDSEVVDVSKKVLihdfvsalpdKYETLVGSNASKL---SGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLV 618
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 169 LNLIEEIKKD---TTILLStHILSDAEEICERFVII---KDGTKIEDTTITELLQRNSENK 223
Cdd:PTZ00265 619 QKTINNLKGNenrITIIIA-HRLSTIRYANTIFVLSnreRGSTVDVDIIGEDPTKDNKENN 678
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
3-161 |
1.75e-06 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 48.25 E-value: 1.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVIS--DIINPNAGEVLLNGIKISKMKRE------IG 74
Cdd:PRK09580 2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAgrEDYEVTGGTVEFKGKDLLELSPEdragegIF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQYP-------NFFHWMTARETLTFMGQLSGLKKEELSKSIPKILEKVGLRGE---ENSKVGtFSGGMKQRLGIAQAL 144
Cdd:PRK09580 82 MAFQYPveipgvsNQFFLQTALNAVRSYRGQEPLDRFDFQDLMEEKIALLKMPEDlltRSVNVG-FSGGEKKRNDILQMA 160
|
170
....*....|....*..
gi 1261024142 145 LHKPSLIVMDEPVSALD 161
Cdd:PRK09580 161 VLEPELCILDESDSGLD 177
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
7-161 |
1.95e-06 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 49.12 E-value: 1.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 7 NVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLL-NGIKISKMKREigylpQYPnfFHW 85
Cdd:PRK15064 6 NITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLdPNERLGKLRQD-----QFA--FEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 86 MTARETLtFMG--QLSGLKKE-ELSKSIPKILEKVGLR-GEENSKVGTFSG----------------------------- 132
Cdd:PRK15064 79 FTVLDTV-IMGhtELWEVKQErDRIYALPEMSEEDGMKvADLEVKFAEMDGytaearagelllgvgipeeqhyglmseva 157
|
170 180 190
....*....|....*....|....*....|
gi 1261024142 133 -GMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:PRK15064 158 pGWKLRVLLAQALFSNPDILLLDEPTNNLD 187
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
15-205 |
2.28e-06 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 49.01 E-value: 2.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 15 KIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLlngikiskMKREIGYLPQYPnffhWM---TARET 91
Cdd:PTZ00243 673 KVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVW--------AERSIAYVPQQA----WImnaTVRGN 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 92 LTF---------------------MGQLSGlkkeelsksipkilekvGLRGEENSKVGTFSGGMKQRLGIAQALLHKPSL 150
Cdd:PTZ00243 741 ILFfdeedaarladavrvsqleadLAQLGG-----------------GLETEIGEKGVNLSGGQKARVSLARAVYANRDV 803
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1261024142 151 IVMDEPVSALDP-IGRREVLNLIEEIKKDTTILLST---HILSDAEEIcerfVIIKDGT 205
Cdd:PTZ00243 804 YLLDDPLSALDAhVGERVVEECFLGALAGKTRVLAThqvHVVPRADYV----VALGDGR 858
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
27-198 |
4.22e-06 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 45.83 E-value: 4.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 27 SGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLngIKISKMKREIGYLPQYPNFfhwmtaretltfmgqlsglkkeel 106
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY--IDGEDILEEVLDQLLLIIV------------------------ 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 107 sksipkilekvglrgeeNSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIE-------EIKKDT 179
Cdd:smart00382 55 -----------------GGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrlllllKSEKNL 117
|
170
....*....|....*....
gi 1261024142 180 TILLSTHILSDAEEICERF 198
Cdd:smart00382 118 TVILTTNDEKDLGPALLRR 136
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
130-220 |
7.36e-06 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 46.85 E-value: 7.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 130 FSGGMKQRLGIAQALLH--KPSLIVMDEPVSALDP--IgrREVLNLIEEIKKDTTILLSTH--ILSDAEEICERFVIIKD 203
Cdd:COG4637 259 LSDGTLRFLALLAALLSprPPPLLCIEEPENGLHPdlL--PALAELLREASERTQVIVTTHspALLDALEPEEVLVLERE 336
|
90 100
....*....|....*....|...
gi 1261024142 204 G------TKIEDTTITELLQRNS 220
Cdd:COG4637 337 DdgetriRRLSDLELPEWLEGYS 359
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
2-176 |
1.42e-05 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 45.00 E-value: 1.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVtKSFKGKIAVNnFSMELqsgecVGLIGPNGAGKSTLI---------------KVISDIINPNAGE-----VLL 61
Cdd:COG0419 4 RLRLENF-RSYRDTETID-FDDGL-----NLIVGPNGAGKSTILeairyalygkarsrsKLRSDLINVGSEEasvelEFE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 62 NGIKISKMKREIGylpQYPNFFHwMTARETLTFMGQLSGLK------------KEELSKSIPKILEKVGLRGE------E 123
Cdd:COG0419 77 HGGKRYRIERRQG---EFAEFLE-AKPSERKEALKRLLGLEiyeelkerlkelEEALESALEELAELQKLKQEilaqlsG 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1261024142 124 NSKVGTFSGGMKQRLGIAQALlhkpsLIVMDepVSALDPIGRREVLNLIEEIK 176
Cdd:COG0419 153 LDPIETLSGGERLRLALADLL-----SLILD--FGSLDEERLERLLDALEELA 198
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
2-215 |
9.34e-05 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 43.45 E-value: 9.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNvtksFKGkiaVNNFSMELQSGECVgLIGPNGAGKSTLIKVISDIINP------------NAGEVLLNGIKI--- 66
Cdd:COG3593 5 KIKIKN----FRS---IKDLSIELSDDLTV-LVGENNSGKSSILEALRLLLGPsssrkfdeedfyLGDDPDLPEIEIelt 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 67 -----SKMKREIGYLPQYPN-------------------------FFHWMTARETLTFmgQLSGLKKEELSKSIpkileK 116
Cdd:COG3593 77 fgsllSRLLRLLLKEEDKEEleealeelneelkealkalnellseYLKELLDGLDLEL--ELSLDELEDLLKSL-----S 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 117 VGLRGEENSKVGTFSGGMKQRLGIA--QALLH-----KPSLIVMDEPVSALDPIGRREVLNLIEEI-KKDTTILLSTH-- 186
Cdd:COG3593 150 LRIEDGKELPLDRLGSGFQRLILLAllSALAElkrapANPILLIEEPEAHLHPQAQRRLLKLLKELsEKPNQVIITTHsp 229
|
250 260
....*....|....*....|....*....
gi 1261024142 187 ILSDAEEICERFVIIKDGTKIEDTTITEL 215
Cdd:COG3593 230 HLLSEVPLENIRRLRRDSGGTTSTKLIDL 258
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
3-161 |
9.35e-05 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 43.70 E-value: 9.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 3 LEIRNVTKSFKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVIS----DIINPN----------AGE-------VLL 61
Cdd:PLN03073 178 IHMENFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMAmhaiDGIPKNcqilhveqevVGDdttalqcVLN 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 62 NGIKISK-MKREIGYLPQYPNF-FHWMTARETltfMGQLSGLKKEELSKSIPKI---LEKVGLRGEEN------------ 124
Cdd:PLN03073 258 TDIERTQlLEEEAQLVAQQRELeFETETGKGK---GANKDGVDKDAVSQRLEEIykrLELIDAYTAEAraasilaglsft 334
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1261024142 125 -----SKVGTFSGGMKQRLGIAQALLHKPSLIVMDEPVSALD 161
Cdd:PLN03073 335 pemqvKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD 376
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1-204 |
1.21e-04 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 43.36 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 1 MKLEIRNVtksfKGKIAVNNFSMELQSGECVGLIGPNGAGKSTLIKVISDIINPNAGEVLLNG--IKISKMKREI----- 73
Cdd:PRK11288 256 VRLRLDGL----KGPGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGkpIDIRSPRDAIragim 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 74 ---------GYLPQYP-----NffhwMTAR-ETLTFMGQLSGLKKEELSKSIPKILeKVGLRGEEnSKVGTFSGGMKQRL 138
Cdd:PRK11288 332 lcpedrkaeGIIPVHSvadniN----ISARrHHLRAGCLINNRWEAENADRFIRSL-NIKTPSRE-QLIMNLSGGNQQKA 405
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 139 GIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEEIKKD--TTILLSthilSDAEE---ICERFVIIKDG 204
Cdd:PRK11288 406 ILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQgvAVLFVS----SDLPEvlgVADRIVVMREG 472
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
18-217 |
2.21e-04 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 42.50 E-value: 2.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 18 VNNFSMELQSGECVGLIGPNGAGKSTLIKVISDII-NPNAGEVLLNGIKIS----------------KMKREIGYLPQY- 79
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYpGKFEGNVFINGKPVDirnpaqairagiamvpEDRKRHGIVPILg 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 80 --PNFFhwMTARETLTFMGQLSGLKKEelsKSIPKILEKVGLR-GEENSKVGTFSGGMKQRLGIAQALLHKPSLIVMDEP 156
Cdd:TIGR02633 356 vgKNIT--LSVLKSFCFKMRIDAAAEL---QIIGSAIQRLKVKtASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEP 430
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1261024142 157 VSALDPIGRREVLNLIEEI-KKDTTILLSTHILSDAEEICERFVIIKDGTKIEDTTITELLQ 217
Cdd:TIGR02633 431 TRGVDVGAKYEIYKLINQLaQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLKGDFVNHALTQ 492
|
|
| COG4938 |
COG4938 |
Predicted ATPase [General function prediction only]; |
2-186 |
1.43e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443965 [Multi-domain] Cd Length: 277 Bit Score: 39.57 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 2 KLEIRNVtKSFKgkiavnNFSMELqsGECVGLIGPNGAGKSTLIKVI-------SDIINPNAGEVLLNGIKISKMKREIG 74
Cdd:COG4938 3 SISIKNF-GPFK------EAELEL--KPLTLLIGPNGSGKSTLIQALllllqsnFIYLPAERSGPARLYPSLVRELSDLG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 75 YLPQY-PNFFHWMTAREtltfmgqLSGLKKEELSKSIPKILEKVGlRGEENSKVGTFSG--------------------G 133
Cdd:COG4938 74 SRGEYtADFLAELENLE-------ILDDKSKELLEQVEEWLEKIF-PGKVEVDASSDLVrlvfrpsgngkriplsnvgsG 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1261024142 134 MKQRLGIAQALLH---KPSLIVMDEPVSALDPIGRREVLNLIEEI-KKDTTILLSTH 186
Cdd:COG4938 146 VSELLPILLALLSaakPGSLLIIEEPEAHLHPKAQSALAELLAELaNSGVQVIIETH 202
|
|
| SbcC_Walker_B |
pfam13558 |
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ... |
118-174 |
1.62e-03 |
|
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.
Pssm-ID: 463921 [Multi-domain] Cd Length: 90 Bit Score: 36.83 E-value: 1.62e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1261024142 118 GLRGEENSKVGTFSGGMKQ-------------RLGIAQALLHKPSLIVMDEPVSALDPIGRREVLNLIEE 174
Cdd:pfam13558 21 GSEVETYRRSGGLSGGEKQllaylplaaalaaQYGSAEGRPPAPRLVFLDEAFAKLDEENIRTALELLRA 90
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
130-186 |
2.36e-03 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 38.91 E-value: 2.36e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1261024142 130 FSGGMKQRLGIAQALL---HKPSLIVMDEPVSALDPIGRREVLNLIEEI-KKDTTILLSTH 186
Cdd:pfam13304 237 LSDGTKRLLALLAALLsalPKGGLLLIDEPESGLHPKLLRRLLELLKELsRNGAQLILTTH 297
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
2-48 |
6.82e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 37.60 E-value: 6.82e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1261024142 2 KLEIRNVtKSFKgkiavnNFSMELqSGECVgLIGPNGAGKSTLIKVI 48
Cdd:COG4637 4 RIRIKNF-KSLR------DLELPL-GPLTV-LIGANGSGKSNLLDAL 41
|
|
| |
