|
Name |
Accession |
Description |
Interval |
E-value |
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1-1020 |
2.34e-63 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 233.71 E-value: 2.34e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 1 MRPIQLIMTAFGPYKQTEVINFDDLGehRIFAISGNTGAGKTTIFDAICYVLYGEASGEERSDTSmLRSQFADDNVYTSV 80
Cdd:TIGR00618 1 MKPLRLTLKNFGSYKGTHTIDFTALG--PIFLICGKTGAGKTTLLDAITYALYGKLPRRSEVIRS-LNSLYAAPSEAAFA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 81 ELTFQLKGKRYEIKRQLGHKKQGNKTITGHAVELYDVMDGEKIPAVdrfHVTDVNKKVEDLIGLSKHQFSQIVMLPQGEF 160
Cdd:TIGR00618 78 ELEFSLGTKIYRVHRTLRCTRSHRKTEQPEQLYLEQKKGRGRILAA---KKSETEEVIHDLLKLDYKTFTRVVLLPQGEF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 161 RKLLTSETENKEEILRRIFKTDRYKLMRELLDQKRKQWKDVLQEKQKERELhfrnvfklpirdgalLETLVEQEHVNTHQ 240
Cdd:TIGR00618 155 AQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQL---------------LTLCTPCMPDTYHE 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 241 VVEALEQETTAYKTEVAQLQLEQDARTKQLKEAETRFHAAKSVNEKFTDLQQKNERYNTLQENRAVIERKETSFRRAEQA 320
Cdd:TIGR00618 220 RKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHI 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 321 KHLLPFEQWHEEAMQNEQKAESLLKQIIVKKENiitsftLAQQKYEVEKNKELERE--DAKKLVQRLEELQSIIASLAEK 398
Cdd:TIGR00618 300 KAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA------HVKQQSSIEEQRRLLQTlhSQEIHIRDAHEVATSIREISCQ 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 399 KLNLQNAEIQLGRLKESMQKLDQLLEEHTNQKQRMSGE---LQQLEQALEQYVAKVEELTNMREDAKVLKQAYDvwQEKQ 475
Cdd:TIGR00618 374 QHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATidtRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAI--TCTA 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 476 KFEQEKEAAYTKMQEAVRAYENME---RRWLSEQAGILALHLH-----DGESCPVCGSTNHPKKATEQSDaidekELNDL 547
Cdd:TIGR00618 452 QCEKLEKIHLQESAQSLKEREQQLqtkEQIHLQETRKKAVVLArllelQEEPCPLCGSCIHPNPARQDID-----NPGPL 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 548 RDKKNVAEKLHVQVEEKWNFYRLQYEQVIEEVMKRGYHSDELVETYSALVQKGKQLAAEVN-TLKESEETRKQIAVNIKS 626
Cdd:TIGR00618 527 TRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPnLQNITVRLQDLTEKLSEA 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 627 VEEKVDELQKQKRE-----------------------AETLQHRTEMECMQ------------LRTSYEHDKQNIPDNLQ 671
Cdd:TIGR00618 607 EDMLACEQHALLRKlqpeqdlqdvrlhlqqcsqelalKLTALHALQLTLTQervrehalsirvLPKELLASRQLALQKMQ 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 672 T----VQAWKAQFDQAMQQLRLMEDEWKKVQEAYQHWQNENIRIQAEHEGasnQFESAKLKKEETLARFMKELEQRGFID 747
Cdd:TIGR00618 687 SekeqLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAA---REDALNQSLKELMHQARTVLKARTEAH 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 748 QLTYKEAKLndaeMEMLQKEIQSYYSSLEVLAKQIEELHAELKDKKfidiTSLGEHIKELEINLDISKEK-RQRAQNAVT 826
Cdd:TIGR00618 764 FNNNEEVTA----ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLE----AEIGQEIPSDEDILNLQCETlVQEEEQFLS 835
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 827 YISDLHENIRRIDEQIHEEEKAFQ----------ELVDLFEVMKGDNESRISFERYILIEYLEQIVQIANERLRKLSNGQ 896
Cdd:TIGR00618 836 RLEEKSATLGEITHQLLKYEECSKqlaqltqeqaKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSEGR 915
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 897 FYLKRSERVEKRNRQSGLGLDVYDAYTGQTRDVKTLSGGEKFNASLCLALGMADVIQAyEGGISIETMFIDEGFGSLDEE 976
Cdd:TIGR00618 916 FHGRYADSHVNARKYQGLALLVADAYTGSVRPSATLSGGETFLASLSLALALADLLST-SGGTVLDSLFIDEGFGSLDED 994
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....
gi 1263152438 977 SLTKAVDALIDLQKSGRFIGVISHVQELKNAMPAVLEVTKQKDG 1020
Cdd:TIGR00618 995 SLDRAIGILDAIREGSKMIGIISHVPEFRERIPHRILVKKTNAG 1038
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
30-1016 |
9.44e-37 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 150.34 E-value: 9.44e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 30 IFAISGNTGAGKTTIFDAICYVLYGEASGEERSDTS----MLRsqfadDNVYTSVELTFQLKGKRYE-IKRQLGHKKQGN 104
Cdd:PRK10246 32 LFAITGPTGAGKTTLLDAICLALYHETPRLNNVSQSqndlMTR-----DTAECLAEVEFEVKGEAYRaFWSQNRARNQPD 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 105 KTITGHAVELYDVMDGeKIPAvDRfhVTDVNKKVEDLIGLSKHQFSQIVMLPQGEFRKLLTSETENKEEILRRIFKTDRY 184
Cdd:PRK10246 107 GNLQAPRVELARCADG-KILA-DK--VKDKLELTATLTGLDYGRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIY 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 185 KLMRELLDQKRKQWKDVLQEKQKErelhfrnVFKLPIRDGALLETLVEQEHVNTHQ-----VVEALEQETTAYKTEVAQL 259
Cdd:PRK10246 183 GQISAMVFEQHKSARTELEKLQAQ-------ASGVALLTPEQVQSLTASLQVLTDEekqllTAQQQQQQSLNWLTRLDEL 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 260 QLEQDARTKQLKEAETRFHAAKSVNEKFTDLQ---QKNERYNTLQENRAVIER-----KETSFRRAEQAKHLLPFEQWHE 331
Cdd:PRK10246 256 QQEASRRQQALQQALAAEEKAQPQLAALSLAQparQLRPHWERIQEQSAALAHtrqqiEEVNTRLQSTMALRARIRHHAA 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 332 EAMQNEQKAESLLKQIIVKKENI-ITSFTLAQQKYEVEKNKElEREDAKKLVQRLEELQSIIASLAEKKLNLQNAEI--- 407
Cdd:PRK10246 336 KQSAELQAQQQSLNTWLAEHDRFrQWNNELAGWRAQFSQQTS-DREQLRQWQQQLTHAEQKLNALPAITLTLTADEVaaa 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 408 --QLGRLKESMQKLDQLLEEHTNQKQRMSgELQQLEQALEQYVAKVEE-LTNMREDAKVLKQAY-DVwqeKQKFEQEkea 483
Cdd:PRK10246 415 laQHAEQRPLRQRLVALHGQIVPQQKRLA-QLQVAIQNVTQEQTQRNAaLNEMRQRYKEKTQQLaDV---KTICEQE--- 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 484 AYTKMQEAVRAyenmerrwlseqagilalHLHDGESCPVCGSTNHPkkATEQSDAIdekELNDLRDKKNVAEKLHVQVEE 563
Cdd:PRK10246 488 ARIKDLEAQRA------------------QLQAGQPCPLCGSTSHP--AVEAYQAL---EPGVNQSRLDALEKEVKKLGE 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 564 KWNFYRLQYEQVIEEVMKRGYHSDELVETYSALVQKGKQLAAEVNT-----------LKESEETRKQIavnikSVEEKVD 632
Cdd:PRK10246 545 EGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCASLNItlqpqddiqpwLDAQEEHERQL-----RLLSQRH 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 633 ELQKQKREAETLQHRTEMECMQLRTSYEHDKQ----NIPDNlQTVQAWKAQFDQAMQQLRLMEDEWKKVQE--------- 699
Cdd:PRK10246 620 ELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAgyalTLPQE-DEEASWLATRQQEAQSWQQRQNELTALQNriqqltpll 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 700 ----------------AYQHWQ---NENIRIQAEHEGASNQFESAKLKKEETLARFMKELEQRGFIDQLTYKEAKLNDAE 760
Cdd:PRK10246 699 etlpqsddlphseetvALDNWRqvhEQCLSLHSQLQTLQQQDVLEAQRLQKAQAQFDTALQASVFDDQQAFLAALLDEET 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 761 MEMLQKEIQSYYSSLE---VLAKQIEELHAELKDKK--FIDITSLGEHI--------KELEINLDISKEKRQRAQNAVTY 827
Cdd:PRK10246 779 LTQLEQLKQNLENQRQqaqTLVTQTAQALAQHQQHRpdGLDLTVTVEQIqqelaqlaQQLRENTTRQGEIRQQLKQDADN 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 828 ISDLHENIRRIDEQIHEEEKaFQELVDLFEVMKGDNesrisFERYILIEYLEQIVQIANERLRKLsNGQFYLKR--SERV 905
Cdd:PRK10246 859 RQQQQALMQQIAQATQQVED-WGYLNSLIGSKEGDK-----FRKFAQGLTLDNLVWLANQQLTRL-HGRYLLQRkaSEAL 931
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 906 EkrnrqsglgLDVYDAYTGQT-RDVKTLSGGEKFNASLCLALGMADVIQAyegGISIETMFIDEGFGSLDEESLTKAVDA 984
Cdd:PRK10246 932 E---------LEVVDTWQADAvRDTRTLSGGESFLVSLALALALSDLVSH---KTRIDSLFLDEGFGTLDSETLDTALDA 999
|
1050 1060 1070
....*....|....*....|....*....|..
gi 1263152438 985 LIDLQKSGRFIGVISHVQELKNAMPAVLEVTK 1016
Cdd:PRK10246 1000 LDALNASGKTIGVISHVEAMKERIPVQIKVKK 1031
|
|
| ABC_sbcCD |
cd03279 |
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
1-170 |
4.64e-35 |
|
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.
Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 133.16 E-value: 4.64e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 1 MRPIQLIMTAFGPYKQTEVINFDDLGEHRIFAISGNTGAGKTTIFDAICYVLYGEASGEERSDtsMLRSQFADDNVYTSV 80
Cdd:cd03279 1 MKPLKLELKNFGPFREEQVIDFTGLDNNGLFLICGPTGAGKSTILDAITYALYGKTPRYGRQE--NLRSVFAPGEDTAEV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 81 ELTFQLKGKRYEIKRQlghkkqgnktitghavelydvmdgekipavdrfhvtdvnkkvedlIGLSKHQFSQIVMLPQGEF 160
Cdd:cd03279 79 SFTFQLGGKKYRVERS---------------------------------------------RGLDYDQFTRIVLLPQGEF 113
|
170
....*....|
gi 1263152438 161 RKLLTSETEN 170
Cdd:cd03279 114 DRFLARPVST 123
|
|
| ABC_sbcCD |
cd03279 |
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
926-1020 |
2.63e-33 |
|
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.
Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 127.77 E-value: 2.63e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 926 TRDVKTLSGGEKFNASLCLALGMADVIQAyEGGISIETMFIDEGFGSLDEESLTKAVDALIDLQKSGRFIGVISHVQELK 1005
Cdd:cd03279 118 ARPVSTLSGGETFLASLSLALALSEVLQN-RGGARLEALFIDEGFGTLDPEALEAVATALELIRTENRMVGVISHVEELK 196
|
90
....*....|....*
gi 1263152438 1006 NAMPAVLEVTKQKDG 1020
Cdd:cd03279 197 ERIPQRLEVIKTPGG 211
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
2-211 |
3.51e-27 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 110.10 E-value: 3.51e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 2 RPIQLIMTAFGPYKQTEVINFDDlgehRIFAISGNTGAGKTTIFDAICYVLYGEASGEERSDTSMLRsqfaDDNVYTSVE 81
Cdd:COG0419 1 KLLRLRLENFRSYRDTETIDFDD----GLNLIVGPNGAGKSTILEAIRYALYGKARSRSKLRSDLIN----VGSEEASVE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 82 LTFQLKGKRYEIKRqlghkkqgnktitghavelydvmdgekipavdrfhvtdvnkkvedliglskhqfsqivmlPQGEFR 161
Cdd:COG0419 73 LEFEHGGKRYRIER------------------------------------------------------------RQGEFA 92
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1263152438 162 KLLTSETENKEEILRRIFKTDRYKLMRELLDQKRKQWKDVLQEKQKEREL 211
Cdd:COG0419 93 EFLEAKPSERKEALKRLLGLEIYEELKERLKELEEALESALEELAELQKL 142
|
|
| AAA_23 |
pfam13476 |
AAA domain; |
6-208 |
4.91e-16 |
|
AAA domain;
Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 77.54 E-value: 4.91e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 6 LIMTAFGPYKQTEvINFDdlgeHRIFAISGNTGAGKTTIFDAICYVLYGEASGEERSD-TSMLRSQFA---DDNVYTSVE 81
Cdd:pfam13476 1 LTIENFRSFRDQT-IDFS----KGLTLITGPNGSGKTTILDAIKLALYGKTSRLKRKSgGGFVKGDIRiglEGKGKAYVE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 82 LTFQLKGKR--YEIKRQLGHKKQGNKTITGHAVELydvmdgekipavdrFHVTDVNKKVEDLIGLSKHQFSQIVMLPQGE 159
Cdd:pfam13476 76 ITFENNDGRytYAIERSRELSKKKGKTKKKEILEI--------------LEIDELQQFISELLKSDKIILPLLVFLGQER 141
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1263152438 160 FRKLLTSETENKEEILRRIFKTDRYKLMRELLDQKRKQWKDVLQEKQKE 208
Cdd:pfam13476 142 EEEFERKEKKERLEELEKALEEKEDEKKLLEKLLQLKEKKKELEELKEE 190
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
927-1022 |
2.24e-15 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 75.72 E-value: 2.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 927 RDVKTLSGGEKFNASLCLALGMADVIqayegGISIETMFIDEGFGSLDEESLTKAVDALIDLQKS--GRFIGVISHVQEL 1004
Cdd:cd03240 111 DMRGRCSGGEKVLASLIIRLALAETF-----GSNCGILALDEPTTNLDEENIEESLAEIIEERKSqkNFQLIVITHDEEL 185
|
90
....*....|....*...
gi 1263152438 1005 KNAMPAVLEVTKQKDGCS 1022
Cdd:cd03240 186 VDAADHIYRVEKDGRQKS 203
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
19-860 |
1.47e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.48 E-value: 1.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 19 VINFDdlgeHRIFAISGNTGAGKTTIFDAICYVLyGEASgeersdTSMLRSQFADDNV-----------YTSVELTF--- 84
Cdd:TIGR02168 18 TINFD----KGITGIVGPNGCGKSNIVDAIRWVL-GEQS------AKALRGGKMEDVIfngsetrkplsLAEVELVFdns 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 85 --QLKGKRYE---IKRQLGHKKQGNKTITGHAVELYDVMdgekipavDRFHVTDVNKKVEDLIGLSKhqFSQIVMLPQGE 159
Cdd:TIGR02168 87 dgLLPGADYSeisITRRLYRDGESEYFINGQPCRLKDIQ--------DLFLDTGLGKRSYSIIEQGK--ISEIIEAKPEE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 160 FRKLL------TSETENKEEILRRIFKTDR-----YKLMRELldqkRKQWKDVlqEKQKERELHFRNVfKLPIR--DGAL 226
Cdd:TIGR02168 157 RRAIFeeaagiSKYKERRKETERKLERTREnldrlEDILNEL----ERQLKSL--ERQAEKAERYKEL-KAELRelELAL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 227 LETLVEQEHVNthqvVEALEQETTAYKTEVAQLQLEQDARTKQLKEAETRFHaakSVNEKFTDLQQKNERYNTLQeNRAV 306
Cdd:TIGR02168 230 LVLRLEELREE----LEELQEELKEAEEELEELTAELQELEEKLEELRLEVS---ELEEEIEELQKELYALANEI-SRLE 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 307 IERKETSFRRAEQAKHLLPFEQWHEEAMQNEQKAESLLKQIIVKKENIITSFTLAQQKYEVEKNKELEREDAKKLVQR-L 385
Cdd:TIGR02168 302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEqL 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 386 EELQSIIASLaEKKLNLQNAEI-----QLGRLKESMQKLDQLLEEH-----TNQKQRMSGEL----QQLEQALEQYVAKV 451
Cdd:TIGR02168 382 ETLRSKVAQL-ELQIASLNNEIerleaRLERLEDRRERLQQEIEELlkkleEAELKELQAELeeleEELEELQEELERLE 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 452 EELTNMREDAKVLKQAYDVWQEKQKFEQEKEAAYTKMQEAVRAYENMERRWLSEQAGILALH--LHDGESCP-------- 521
Cdd:TIGR02168 461 EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvLSELISVDegyeaaie 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 522 -VCGST----------------NHPKKA-----------TEQSDAIDEKELNDLRDKKNVAE--KLHVQVEEKW------ 565
Cdd:TIGR02168 541 aALGGRlqavvvenlnaakkaiAFLKQNelgrvtflpldSIKGTEIQGNDREILKNIEGFLGvaKDLVKFDPKLrkalsy 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 566 ------------------NFYRLQYEQVIEE---VMKRGYHSDELVETYSALVQKGKQLAAEVNTLKESEETRKQIAVNI 624
Cdd:TIGR02168 621 llggvlvvddldnalelaKKLRPGYRIVTLDgdlVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKAL 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 625 KSVEEKVDELQKQKREAETLQHRTEMECMQLRTSYEHDKQNIPDNLQTVQAWKAQFDQAMQQLRLMEDEWKKVQEAYQHW 704
Cdd:TIGR02168 701 AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 705 QNENIRIQAEHEGASNQFESAklkkEETLARFMKEL-EQRGFIDQLTYKEAKLnDAEMEMLQKEIQSYYSSLEVLAKQIE 783
Cdd:TIGR02168 781 EAEIEELEAQIEQLKEELKAL----REALDELRAELtLLNEEAANLRERLESL-ERRIAATERRLEDLEEQIEELSEDIE 855
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1263152438 784 ELHAELKDKKfidiTSLGEHIKELEINLDISKEKRQRAQNAVTYISDLHENIRRIDEQIHEEEKAFQELVDLFEVMK 860
Cdd:TIGR02168 856 SLAAEIEELE----ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
33-1016 |
2.88e-13 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 74.17 E-value: 2.88e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 33 ISGNTGAGKTTIFDAICYVLYGEASGEERSDtsMLRSqfadDNVYTSVELTFQLKGKRYEIKRQLGHKKQGNKTitghav 112
Cdd:PRK01156 28 ITGKNGAGKSSIVDAIRFALFTDKRTEKIED--MIKK----GKNNLEVELEFRIGGHVYQIRRSIERRGKGSRR------ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 113 ELYDVMDGEKIPAvdrfHVTDVNKKVE-DLIGLSKHQFSQIVMLPQGEFRKLLTSETENKEEILRRIFKTDR----YKLM 187
Cdd:PRK01156 96 EAYIKKDGSIIAE----GFDDTTKYIEkNILGISKDVFLNSIFVGQGEMDSLISGDPAQRKKILDEILEINSlernYDKL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 188 RELLDQKRKQWKDV--LQEKQKERELHFRNVFKlPIRDGALLETLVEQEHVNTHQVVEALEQETTAYKTEVAQLQLEQDA 265
Cdd:PRK01156 172 KDVIDMLRAEISNIdyLEEKLKSSNLELENIKK-QIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDM 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 266 RTK---QLKEAETRFhaaKSVNEKFTDLQQKNERYNTLQENRAVIERKETSfrraeqakhllpfEQWheeamqneqkaeS 342
Cdd:PRK01156 251 KNRyesEIKTAESDL---SMELEKNNYYKELEERHMKIINDPVYKNRNYIN-------------DYF------------K 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 343 LLKQIIVKKEnIITSFTLAQQKYE--VEKNKELE--REDAKKLVQRLEELQSIIASLAEKKLNLQNAeiqlgrlKESMQK 418
Cdd:PRK01156 303 YKNDIENKKQ-ILSNIDAEINKYHaiIKKLSVLQkdYNDYIKKKSRYDDLNNQILELEGYEMDYNSY-------LKSIES 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 419 LDQLLEEHTNQKQRMSGELQQLeqaLEQYVAKVEELTNMREDAKVLKQAYDvwQEKQKFEQEKEAAYTKMQEavrayenm 498
Cdd:PRK01156 375 LKKKIEEYSKNIERMSAFISEI---LKIQEIDPDAIKKELNEINVKLQDIS--SKVSSLNQRIRALRENLDE-------- 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 499 errwLSEQAGILALHlhdgESCPVCGSTnhpkKATEQSDAIDE---KELNDLRDKKNVAEKLHVQVEEKWNFYRLQYEQV 575
Cdd:PRK01156 442 ----LSRNMEMLNGQ----SVCPVCGTT----LGEEKSNHIINhynEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYL 509
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 576 IEEVMKRGYHSDELVETYSALVQKGKQlaaEVNTLKESEETRKQIAVNIKSVEEkvdELQKQKREaetlqhrtemecmql 655
Cdd:PRK01156 510 ESEEINKSINEYNKIESARADLEDIKI---KINELKDKHDKYEEIKNRYKSLKL---EDLDSKRT--------------- 568
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 656 rtsyEHDKQNIPDNLQTVQAWKAQFDQAMQQLRLMEDEwkkvqeayqhwqneniriqaehegaSNQFESAKLKKEETLAR 735
Cdd:PRK01156 569 ----SWLNALAVISLIDIETNRSRSNEIKKQLNDLESR-------------------------LQEIEIGFPDDKSYIDK 619
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 736 FMKELEQRGFIDQLTYKEAKLNDAEMEMLQKEIQSYysslevlAKQIEELHAELKDKKFID--ITSLGEHIKELEINLDI 813
Cdd:PRK01156 620 SIREIENEANNLNNKYNEIQENKILIEKLRGKIDNY-------KKQIAEIDSIIPDLKEITsrINDIEDNLKKSRKALDD 692
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 814 SKEKRQRAQNAV----TYISDLHENIRRIDEQIHEEEKAFQELVDLFEVMKGDNESRISferyilieylEQIVQIANERL 889
Cdd:PRK01156 693 AKANRARLESTIeilrTRINELSDRINDINETLESMKKIKKAIGDLKRLREAFDKSGVP----------AMIRKSASQAM 762
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 890 RKLSNGqfYLKRSE-RVEKRNRQSGLGLDVYDAytGQTRDVKTLSGGEKFNASLCLALGMADVIQAyeggiSIETMFIDE 968
Cdd:PRK01156 763 TSLTRK--YLFEFNlDFDDIDVDQDFNITVSRG--GMVEGIDSLSGGEKTAVAFALRVAVAQFLNN-----DKSLLIMDE 833
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|.
gi 1263152438 969 GFGSLDEESLTKAVDAL-IDLQKSGRF--IGVISHVQELKNAMPAVLEVTK 1016
Cdd:PRK01156 834 PTAFLDEDRRTNLKDIIeYSLKDSSDIpqVIMISHHRELLSVADVAYEVKK 884
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
375-1005 |
6.95e-12 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 69.41 E-value: 6.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 375 REDAKKLVQRLEELQSIIASLAEKKLNLQNAEIQLGRLKESMQKLDQLLE--EHTNQKQRMSGELQQLEQALEQYVAKVE 452
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 453 ELTNMREDAKVLKQAYDVWQEK--QKFEQEKEAAYTKMQEAVRAYENMERRWLSEQAGIlalhlhdgescpvcgstnhpk 530
Cdd:COG4717 157 ELRELEEELEELEAELAELQEEleELLEQLSLATEEELQDLAEELEELQQRLAELEEEL--------------------- 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 531 KATEQSDAIDEKELNDLRDKKNVAEKLHvQVEEKWNFYRLqyEQVIEEVMKRGYHSDELVETYSALVQKGKQLAAEVNTL 610
Cdd:COG4717 216 EEAQEELEELEEELEQLENELEAAALEE-RLKEARLLLLI--AAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLL 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 611 KESEETrkqiavnikSVEEKVDELQKQKREAETLQHRTEMECMQLRTSYEHDKQNIPDNLQTVQAWKAQFDQAMQQLRLM 690
Cdd:COG4717 293 LAREKA---------SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 691 EdewkkVQEAYQHWQNENIRIQAEHEGASNQFESAKLKKEETLARFmKELEQRgFIDQLTYKEAKLNDAEMEMLQKEIQS 770
Cdd:COG4717 364 Q-----LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEEL-EELEEQ-LEELLGELEELLEALDEEELEEELEE 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 771 YYSSLEVLAKQIEELHAELKDkkfiditsLGEHIKELEINLDISKEKRQRAQnavtyisdlhenirrIDEQIHEEEKAFQ 850
Cdd:COG4717 437 LEEELEELEEELEELREELAE--------LEAELEQLEEDGELAELLQELEE---------------LKAELRELAEEWA 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 851 ELVDLFEVMkgdNESRISFERyiliEYLEQIVQIANERLRKLSNGQFylkrservEKRNRQSGLGLDVYDAyTGQTRDVK 930
Cdd:COG4717 494 ALKLALELL---EEAREEYRE----ERLPPVLERASEYFSRLTDGRY--------RLIRIDEDLSLKVDTE-DGRTRPVE 557
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1263152438 931 TLSGGEKFNASLCLALGMADVIQAYeggisIETMFIDEGFGSLDEESLTKAVDALIDLQKSGRFIGVISHVQELK 1005
Cdd:COG4717 558 ELSRGTREQLYLALRLALAELLAGE-----PLPLILDDAFVNFDDERLRAALELLAELAKGRQVIYFTCHEELVE 627
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
6-97 |
1.62e-11 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 64.55 E-value: 1.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 6 LIMTAFGPYKQTEVINFDDLgehrIFAISGNTGAGKTTIFDAICYVLYGEASGEERS---DTSMLRSQfaddNVYTSVEL 82
Cdd:cd03240 4 LSIRNIRSFHERSEIEFFSP----LTLIVGQNGAGKTTIIEALKYALTGELPPNSKGgahDPKLIREG----EVRAQVKL 75
|
90
....*....|....*.
gi 1263152438 83 TFQL-KGKRYEIKRQL 97
Cdd:cd03240 76 AFENaNGKKYTITRSL 91
|
|
| SbcC_Walker_B |
pfam13558 |
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ... |
927-985 |
1.02e-10 |
|
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.
Pssm-ID: 463921 [Multi-domain] Cd Length: 90 Bit Score: 59.17 E-value: 1.02e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1263152438 927 RDVKTLSGGEK-FNASLCLALGMADVIQAYEG-GISIETMFIDEGFGSLDEESLTKAVDAL 985
Cdd:pfam13558 28 RRSGGLSGGEKqLLAYLPLAAALAAQYGSAEGrPPAPRLVFLDEAFAKLDEENIRTALELL 88
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
32-482 |
1.27e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.86 E-value: 1.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 32 AISGNTGAGKTTIFDAICYVLYGEASGEERSDT-SML--RSQFADDNVYTSVELTFQLKGKR----YEIKRQLGHKKQGN 104
Cdd:TIGR02169 27 VISGPNGSGKSNIGDAILFALGLSSSKAMRAERlSDLisNGKNGQSGNEAYVTVTFKNDDGKfpdeLEVVRRLKVTDDGK 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 105 KT---ITGHAVELYDVMDgekipAVDRFHVT----------DVNKkvedliglskhqfsqIVMLPQGEFRKLL-----TS 166
Cdd:TIGR02169 107 YSyyyLNGQRVRLSEIHD-----FLAAAGIYpegynvvlqgDVTD---------------FISMSPVERRKIIdeiagVA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 167 ETENKEEILRRIFKTDRYKLMR--ELLDQKRKQwkdvLQEKQKERElhfrnvfkLPIRDGALLETLVEQEHVNTHQVVEA 244
Cdd:TIGR02169 167 EFDRKKEKALEELEEVEENIERldLIIDEKRQQ----LERLRRERE--------KAERYQALLKEKREYEGYELLKEKEA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 245 LEQETTAYKTEVAQLQLEQDARTKQLKEAETRFHAA----KSVNEKFTDLQQknERYNTLQENRAVIERKETSFRRAEQA 320
Cdd:TIGR02169 235 LERQKEAIERQLASLEEELEKLTEEISELEKRLEEIeqllEELNKKIKDLGE--EEQLRVKEKIGELEAEIASLERSIAE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 321 KhllpfEQWHEEAMQNEQKAESLLKQIIVKKENIITSftLAQQKYEVEKNKELEREDAKKLVQRLEELQSIIASLAEKKL 400
Cdd:TIGR02169 313 K-----ERELEDAEERLAKLEAEIDKLLAEIEELERE--IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 401 NLQNAEIQLGRLKESMQKLDQLLEEHTNQKQRMSGELQQLEQALEQYVAKVEELTNMREDAkvlkqAYDVWQEKQKFEQE 480
Cdd:TIGR02169 386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDK-----ALEIKKQEWKLEQL 460
|
..
gi 1263152438 481 KE 482
Cdd:TIGR02169 461 AA 462
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
33-1015 |
1.46e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 65.47 E-value: 1.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 33 ISGNTGAGKTTIFDAICYVLYGeasGEERSDTSMLRSQFADDNVY-TSVELTFQLKGKRYEIKRQLghkKQGNKTITGHa 111
Cdd:PRK03918 28 IIGQNGSGKSSILEAILVGLYW---GHGSKPKGLKKDDFTRIGGSgTEIELKFEKNGRKYRIVRSF---NRGESYLKYL- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 112 velydvmdgeKIPAVDRFHVTDVNKKVEDLIGLskHQFSQIVMLPQGEFRKLLTSEtENKEEILRRIFKTDRYklmrell 191
Cdd:PRK03918 101 ----------DGSEVLEEGDSSVREWVERLIPY--HVFLNAIYIRQGEIDAILESD-ESREKVVRQILGLDDY------- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 192 DQKRKQWKDVLQEKQKERELhfrnvfklpirdgalLETLVEQEHvNTHQVVEALEQETTAYKTEVAQLQLEQDARTKQLK 271
Cdd:PRK03918 161 ENAYKNLGEVIKEIKRRIER---------------LEKFIKRTE-NIEELIKEKEKELEEVLREINEISSELPELREELE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 272 EAETRFHAAKSVNEKFTDLQQKNERYNtlQENRAVIER-KETSFRRAEQAKHLLPFEQWHEEAMQNEQKAESLLKQIIVK 350
Cdd:PRK03918 225 KLEKEVKELEELKEEIEELEKELESLE--GSKRKLEEKiRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFY 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 351 KEniitsftLAQQKYEVEKNKELEREDAKKLVQRLEELQSIIASLAEKKLNLQNAEIQLGRLKESMQKLDQLLeehtnqk 430
Cdd:PRK03918 303 EE-------YLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK------- 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 431 qRMSGELQQLEQALEQYvaKVEELTNMREDAkvlkqaydvwqEKQKFEQEKEaaytkMQEAVRAYENMERRWLSEQAGIL 510
Cdd:PRK03918 369 -AKKEELERLKKRLTGL--TPEKLEKELEEL-----------EKAKEEIEEE-----ISKITARIGELKKEIKELKKAIE 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 511 ALHLHDGEsCPVCGstnhpkkateqsdaideKELNDlRDKKNVAEKLHVQVEEkwnfyrlqyeqvIEEVMKrgyhsdELV 590
Cdd:PRK03918 430 ELKKAKGK-CPVCG-----------------RELTE-EHRKELLEEYTAELKR------------IEKELK------EIE 472
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 591 ETYSALVQKGKQLAAEVNtlKESEETR-KQIAVNIKSVEEKVDELQKQKREAETLQHRTEMEcmqLRTSYEHDKQNIPDN 669
Cdd:PRK03918 473 EKERKLRKELRELEKVLK--KESELIKlKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKE---KLIKLKGEIKSLKKE 547
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 670 LQTVQAWKaqfdqamQQLRLMEDEWKKVQEayqhwQNENIRIQAEHEGASNqFESAKLKKEETLARFMKELEQRGFIDQL 749
Cdd:PRK03918 548 LEKLEELK-------KKLAELEKKLDELEE-----ELAELLKELEELGFES-VEELEERLKELEPFYNEYLELKDAEKEL 614
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 750 TYKEAKLNDA--EMEMLQKEIQSYYSSLEVLAKQIEELHAELKDKKFIDI----TSLGEHIKELEINLDISKEKRQraqn 823
Cdd:PRK03918 615 EREEKELKKLeeELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELreeyLELSRELAGLRAELEELEKRRE---- 690
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 824 avtyisDLHENIRRIDEQIHEEEKAFQELVDLFEVMKGDNESRISFERY--ILIEY-LEQIVQIANERLRKLSNGqfylK 900
Cdd:PRK03918 691 ------EIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYkaLLKERaLSKVGEIASEIFEELTEG----K 760
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 901 RSERVEKRNRQSglgLDVYDAYTGQTRDVKTLSGGEKFNASLCLALGMAdviqAYEGGiSIETMFIDEGFGSLDEESLTK 980
Cdd:PRK03918 761 YSGVRVKAEENK---VKLFVVYQGKERPLTFLSGGERIALGLAFRLALS----LYLAG-NIPLLILDEPTPFLDEERRRK 832
|
970 980 990
....*....|....*....|....*....|....*
gi 1263152438 981 AVDALIDLQKSGRFIGVISHVQELKNAMPAVLEVT 1015
Cdd:PRK03918 833 LVDIMERYLRKIPQVIIVSHDEELKDAADYVIRVS 867
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
5-911 |
7.03e-10 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 63.45 E-value: 7.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 5 QLIMTAFGPYKQTEVINFDdlgeHRIFAISGNTGAGKTTIFDAICYVLYGEASGEERSD--TSMLRSQFADDNVYTSVEL 82
Cdd:pfam02463 4 RIEIEGFKSYAKTVILPFS----PGFTAIVGPNGSGKSNILDAILFVLGERSAKSLRSErlSDLIHSKSGAFVNSAEVEI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 83 TFQLKGKR-------YEIKRQLGHKKQGNKTITGHAVELYDVMDGEKipavdrfhvtdvnkkvedLIGLSKHQFSQIVMl 155
Cdd:pfam02463 80 TFDNEDHElpidkeeVSIRRRVYRGGDSEYYINGKNVTKKEVAELLE------------------SQGISPEAYNFLVQ- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 156 pQGEFRKLLTSE----TENKEEILRRIFKTDRY----KLMRELLDQKRKQWKDVLQEKQKERELhfrNVFKLPIRDGALL 227
Cdd:pfam02463 141 -GGKIEIIAMMKperrLEIEEEAAGSRLKRKKKealkKLIEETENLAELIIDLEELKLQELKLK---EQAKKALEYYQLK 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 228 ETLVEQEHVNTHQVVEALEQETTAYKTEVAQLQLEQDARTKQL--KEAETRFHAAKSVNEKFTDLQQKNERYNTLQENRA 305
Cdd:pfam02463 217 EKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEieKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 306 VIERKETSFRRAEQAKHLLpfEQWHEEAMQNEQKAESLLKQIIVKKENIITSFTLAQQKYEVEK--------NKELERED 377
Cdd:pfam02463 297 ELKSELLKLERRKVDDEEK--LKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEeeleklqeKLEQLEEE 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 378 AKKLVQRLEELQSIIASLAEKKLNLQNAEIQ--LGRLKESMQKLDQLLEEHtNQKQRMSGELQQLEQALEQYVAKVEELT 455
Cdd:pfam02463 375 LLAKKKLESERLSSAAKLKEEELELKSEEEKeaQLLLELARQLEDLLKEEK-KEELEILEEEEESIELKQGKLTEEKEEL 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 456 NMREDAKVLKQAYDVWQEKQKFEQEKEAAYTKMQEAVRAYENMERR--WLSEQAGILALHLHDGESCPVCGSTNHPKKAT 533
Cdd:pfam02463 454 EKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSqkESKARSGLKVLLALIKDGVGGRIISAHGRLGD 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 534 EQSDAIDEKELNDLRDkKNVAEKLHVQVEEKWNFYRLQYEQVIEEVMKRGYHSDELVETYSALVQKGKQLAAEVNTLKes 613
Cdd:pfam02463 534 LGVAVENYKVAISTAV-IVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK-- 610
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 614 eetRKQIAVNIKSVEEKVDELQKQKREAETLQHRTEMECMQLRTSYEHDKQNIPDNLQTVQAWKAQFDQAMQQLrlmeDE 693
Cdd:pfam02463 611 ---ATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQEL----QE 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 694 WKKVQEAYQHWQNENIRIQAEHEGASNQFESAKLKKEETLARFMKELEQRGfidQLTYKEAKLNDAEMEMLQKEIQSYYS 773
Cdd:pfam02463 684 KAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI---NEELKLLKQKIDEEEEEEEKSRLKKE 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 774 SLEVLAKQIEELHAELKDKKFIDITSLGEHIKELEINLDISKEKRQRAQNAVTYISDLHENIRRIDEQIHEEEKAFQELV 853
Cdd:pfam02463 761 EKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELAL 840
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*...
gi 1263152438 854 DLFEVMKGDNESRISFERYILIEYLEQIVQIANERLRKLSNGQFYLKRSERVEKRNRQ 911
Cdd:pfam02463 841 ELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEE 898
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
162-638 |
1.20e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.85 E-value: 1.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 162 KLLTSETENKEEILRR----IFKTDRYKLMRELLDQKRKQWKDVLQEKQKERELHFRNVFKLPIRDGALLETLVEQEHVN 237
Cdd:PTZ00121 1370 EKKKEEAKKKADAAKKkaeeKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 238 THQVVEALEQETTAYKTEVAQLQLEQDARTKQLKEAETRFHAAKSVNEKFTDLQQKNERYNTLQENRAVIE-RKETSFRR 316
Cdd:PTZ00121 1450 KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEaKKADEAKK 1529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 317 AEQAKHLlpfeqwhEEAMQNEQ--KAESLLKQIIVKKeniitsftlAQQKYEVEKNKElEREDAKKLVQRLEELQSIIAS 394
Cdd:PTZ00121 1530 AEEAKKA-------DEAKKAEEkkKADELKKAEELKK---------AEEKKKAEEAKK-AEEDKNMALRKAEEAKKAEEA 1592
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 395 LAEKKLNLQNAEI-----QLGRLKESMQKLDQLLEEHTNQKQrmsgeLQQLEQALEQYVAKVEELTNMREDAKVLKQayd 469
Cdd:PTZ00121 1593 RIEEVMKLYEEEKkmkaeEAKKAEEAKIKAEELKKAEEEKKK-----VEQLKKKEAEEKKKAEELKKAEEENKIKAA--- 1664
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 470 vwQEKQKFEQEKEAAY--------TKMQEAVRAYENMERRWLSEQAGILALHLHDGESCPVCGSTNHPK----KATEQSD 537
Cdd:PTZ00121 1665 --EEAKKAEEDKKKAEeakkaeedEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKaeeaKKEAEED 1742
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 538 AIDEKELNDLRDKKNVAEKLHVQVEEKWNFYRLQYEQVIEE---------VMKRGYHSDELVETYSALVQKGKQLAAEVN 608
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEeldeedekrRMEVDKKIKDIFDNFANIIEGGKEGNLVIN 1822
|
490 500 510
....*....|....*....|....*....|.
gi 1263152438 609 TLKESEETR-KQIAVNIKSVEEKVDELQKQK 638
Cdd:PTZ00121 1823 DSKEMEDSAiKEVADSKNMQLEEADAFEKHK 1853
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
106-873 |
1.36e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.38 E-value: 1.36e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 106 TITGHAVELYDVMDGEKIPAVDRFHVTDVNKKVEDLIGLSKH--QFSQIVMLPQ-GEFRKLLTSETENKEEILRRIFKTD 182
Cdd:PTZ00121 1012 ALTANTIDFNQNFNIEKIEELTEYGNNDDVLKEKDIIDEDIDgnHEGKAEAKAHvGQDEGLKPSYKDFDFDAKEDNRADE 1091
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 183 RYKLMRELLDQKRKQWKDVLQEKQKERELHFR--NVFKLP-IRDGALLETLVEQEHVNTHQVVEALEQETTAYKTEVAQ- 258
Cdd:PTZ00121 1092 ATEEAFGKAEEAKKTETGKAEEARKAEEAKKKaeDARKAEeARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARk 1171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 259 ----------LQLEQDARTKQLKEAET--RFHAA-KSVNEKFTDLQQKNERYNTLQENRAVIE--RKETSFRRAEQAKHL 323
Cdd:PTZ00121 1172 aedakkaeaaRKAEEVRKAEELRKAEDarKAEAArKAEEERKAEEARKAEDAKKAEAVKKAEEakKDAEEAKKAEEERNN 1251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 324 LPFEQWHEEAM------QNEQKAESLLKQIIVKKENIITSFTLAQQKYEVEKNKEL-----EREDAKKLVQRLEELQSII 392
Cdd:PTZ00121 1252 EEIRKFEEARMahfarrQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAkkkaeEAKKADEAKKKAEEAKKKA 1331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 393 ASLAEKKLNLQNA-EIQLGRLKESMQKLDQLLEEHTNQKQRMSGELQQLEQALE--QYVAKVEELTN-MREDAKVLKQAY 468
Cdd:PTZ00121 1332 DAAKKKAEEAKKAaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKkaEEKKKADEAKKkAEEDKKKADELK 1411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 469 DVWQEKQKFEQEKEAAYTKmQEAVRAYENMERRWLSEQAGILALHLHDGEscpvcgstNHPKKATEQSDAideKELNDLR 548
Cdd:PTZ00121 1412 KAAAAKKKADEAKKKAEEK-KKADEAKKKAEEAKKADEAKKKAEEAKKAE--------EAKKKAEEAKKA---DEAKKKA 1479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 549 DKKNVAEKLHVQVEEKwnfyrlqyEQVIEEVMKRGYHSDELVETYSALVQKGKQLAAEVNTLKESEETRKqiAVNIKSVE 628
Cdd:PTZ00121 1480 EEAKKADEAKKKAEEA--------KKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKK--AEEKKKAD 1549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 629 E--KVDELQK--QKREAETLQHRTEMECMQLRTSYEHDKQNIPDNLQTVQAWKAQFDQAMQQLRLMEDEWKKVQEAYQHW 704
Cdd:PTZ00121 1550 ElkKAEELKKaeEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAE 1629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 705 QNENIRIQAEHEGASNQFESAKLKKEETLARFMKELEQRgfidqltykEAKLNDAEMEMLQKEIQSYYSSLEVLAKQIEE 784
Cdd:PTZ00121 1630 EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK---------KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE 1700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 785 LHA--ELKDKKFIDITSLGEHIKELEINLDISKEKRQRAQNAVTYISDLH---------ENIRRIDEQIHEEEKAFQELV 853
Cdd:PTZ00121 1701 AKKaeELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKkdeeekkkiAHLKKEEEKKAEEIRKEKEAV 1780
|
810 820
....*....|....*....|
gi 1263152438 854 DLFEVMKGDNESRISFERYI 873
Cdd:PTZ00121 1781 IEEELDEEDEKRRMEVDKKI 1800
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1-834 |
1.54e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 58.90 E-value: 1.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 1 MRPIQLIMTAFGPYKQTEViNFDDlgehRIFAISGNTGAGKTTIFDAICYVLYGEASGEERSDTSMLRSqfADDnvyTSV 80
Cdd:PRK02224 1 MRFDRVRLENFKCYADADL-RLED----GVTVIHGVNGSGKSSLLEACFFALYGSKALDDTLDDVITIG--AEE---AEI 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 81 ELTFQLKGKRYEIKRQLghKKQGNKTITGHAVelydVMDGEKIpaVDRfhVTDVNKKVEDLIGLSKHQFSQIVMLPQGEF 160
Cdd:PRK02224 71 ELWFEHAGGEYHIERRV--RLSGDRATTAKCV----LETPEGT--IDG--ARDVREEVTELLRMDAEAFVNCAYVRQGEV 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 161 RKLLTSETENKEEILRRIFKTDRYKLMRELLDQKRKQWKDVLQEKqkerelhfRNVFklpirdGALLETLVEQEHVNTHQ 240
Cdd:PRK02224 141 NKLINATPSDRQDMIDDLLQLGKLEEYRERASDARLGVERVLSDQ--------RGSL------DQLKAQIEEKEEKDLHE 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 241 VVEALEQETTAYKTEVAQLQLEQDARTKQLKEAETRFHAAKSVNEKFTDLQQKNERyntLQENRAVIERKETSFRRAEQa 320
Cdd:PRK02224 207 RLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIED---LRETIAETEREREELAEEVR- 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 321 khllpfeqwheeamqnEQKAESLlkqiivkkeniitsfTLAQQKYEVEKNKELEREDAKKLVQRLEELQ----SIIASLA 396
Cdd:PRK02224 283 ----------------DLRERLE---------------ELEEERDDLLAEAGLDDADAEAVEARREELEdrdeELRDRLE 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 397 EKKLNLQNAEIQLGRLKESMQKLDQLLEEHTNQKQRMSGELQQLEQALEQYVAKVEELtnmREDAKVLKQAYDVWQEKQK 476
Cdd:PRK02224 332 ECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEL---EEEIEELRERFGDAPVDLG 408
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 477 FEQEKEAAYTKMQEAVRAYENMERRWLSEQAGIL--ALHLHDGESCPVCGstnHPKKATEQSDAIDEKelndlRDKKnva 554
Cdd:PRK02224 409 NAEDFLEELREERDELREREAELEATLRTARERVeeAEALLEAGKCPECG---QPVEGSPHVETIEED-----RERV--- 477
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 555 EKLHVQVEEkwnfyrlqYEQVIEEVMKRGYHSDELVETysalvqkgkqlAAEVNTLKESEETRKQ-IAVNIKSVEEKVDE 633
Cdd:PRK02224 478 EELEAELED--------LEEEVEEVEERLERAEDLVEA-----------EDRIERLEERREDLEElIAERRETIEEKRER 538
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 634 LQKQKREAEtlQHRTEMECMQLRTSYEHDK-QNIPDNLQTVQAWKAQFDQAMQQLRLMEDEWKKVQEAYQhwQNENIRIQ 712
Cdd:PRK02224 539 AEELRERAA--ELEAEAEEKREAAAEAEEEaEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAED--EIERLREK 614
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 713 AEHEGASNQFESAKLKkeetlarfmkelEQRGFIDQLtykEAKLNDAEMEMLQKEIQSYYSSLEVLAKQIEELHAElKDK 792
Cdd:PRK02224 615 REALAELNDERRERLA------------EKRERKREL---EAEFDEARIEEAREDKERAEEYLEQVEEKLDELREE-RDD 678
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 1263152438 793 KFIDITSLGEHIKELEiNLdisKEKRQRAQNAVTYISDLHEN 834
Cdd:PRK02224 679 LQAEIGAVENELEELE-EL---RERREALENRVEALEALYDE 716
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
858-1001 |
2.15e-08 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 55.40 E-value: 2.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 858 VMKGDNESRISFE------RYILI----EYLEQIVQIANER---LRKLSNGQFYLKRSERVEKRNRQSGLGLDVYDAYTG 924
Cdd:COG0419 62 INVGSEEASVELEfehggkRYRIErrqgEFAEFLEAKPSERkeaLKRLLGLEIYEELKERLKELEEALESALEELAELQK 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 925 QTR----------DVKTLSGGEKfnaslcLALGMADVIQayeggisietMFIDegFGSLDEESLTKAVDALIDLQksgrf 994
Cdd:COG0419 142 LKQeilaqlsgldPIETLSGGER------LRLALADLLS----------LILD--FGSLDEERLERLLDALEELA----- 198
|
....*..
gi 1263152438 995 igVISHV 1001
Cdd:COG0419 199 --IITHV 203
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
240-759 |
1.40e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.92 E-value: 1.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 240 QVVEALEQETTAYKTEVAQLQLEQ-----DARTKQLKEAETRFHAAKSVNEKFTDLQQKNERYNTLQENRAVIERK--ET 312
Cdd:PTZ00121 1303 KADEAKKKAEEAKKADEAKKKAEEakkkaDAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKkaDA 1382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 313 SFRRAEQAKHLlpfEQWHEEAMQNEQKAESLLKQIIVKKE-NIITSFTLAQQKYEVEKNKELEREDAKKLVQRLEELQSi 391
Cdd:PTZ00121 1383 AKKKAEEKKKA---DEAKKKAEEDKKKADELKKAAAAKKKaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK- 1458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 392 iASLAEKKLNLQNAEIQLGRLKESMQKLDQLLEEHTNQKQRmSGELQQLEQALEqyvaKVEELTNMREDAKV--LKQAyd 469
Cdd:PTZ00121 1459 -AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKK-ADEAKKAAEAKK----KADEAKKAEEAKKAdeAKKA-- 1530
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 470 vwQEKQKFEQEKEAAYTKMQEAVRAYEnmERRWLSEQAGILALHLHDGESCPVCGSTNHPKKATEQSdaIDEKELNDLRD 549
Cdd:PTZ00121 1531 --EEAKKADEAKKAEEKKKADELKKAE--ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR--IEEVMKLYEEE 1604
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 550 KKNVAEKLHVQVEEKWNFYRLQYEqviEEVMKRgyhSDELVETYSALVQKGKQL--AAEVNTLKESEETRKQIAVNIKSV 627
Cdd:PTZ00121 1605 KKMKAEEAKKAEEAKIKAEELKKA---EEEKKK---VEQLKKKEAEEKKKAEELkkAEEENKIKAAEEAKKAEEDKKKAE 1678
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 628 E-EKVDELQKQKREAETLQHRTEMECMQLRTSYEHDKQNIPdnlQTVQAWKAQFDQAMQQLRLMEDEWKKVQEAYQHWQN 706
Cdd:PTZ00121 1679 EaKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAE---ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE 1755
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 1263152438 707 ENIRIQAEHEGASNQFESAKLKKEETLARFMKELEQRGFIDQLTYKEAKLNDA 759
Cdd:PTZ00121 1756 KKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFA 1808
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
243-512 |
2.43e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.94 E-value: 2.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 243 EALEQETTAYKTEVAQLQLEQDARTKQLKEAE------TRFHAAKSVNEKFTDLQQKNERYNTLQENRAVIERKEtsfRR 316
Cdd:COG1196 223 KELEAELLLLKLRELEAELEELEAELEELEAEleeleaELAELEAELEELRLELEELELELEEAQAEEYELLAEL---AR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 317 AEQAKHLLpfeqwHEEAMQNEQKAESLLKQIIVKKENIIT-SFTLAQQKYEVEKNKELEREDAKKLVQRLEELQSIIASL 395
Cdd:COG1196 300 LEQDIARL-----EERRRELEERLEELEEELAELEEELEElEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 396 AEKKLNLQNAEIQLGRLKESMQKLDQLLEEHTNQKQRMSGELQQLEQALEQYVAKVEELTNMREDAKvlKQAYDVWQEKQ 475
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE--EALEEAAEEEA 452
|
250 260 270
....*....|....*....|....*....|....*..
gi 1263152438 476 KFEQEKEAAYTKMQEAVRAYENMERRWLSEQAGILAL 512
Cdd:COG1196 453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
157-741 |
3.39e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.56 E-value: 3.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 157 QGEFRKLLTSETENKEEILRRIFKTDRYKLMRELLDQKRKQWKDVLQEKQKERELHFRNVFKLpIRDGALLETLVEQEHV 236
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL-EQDIARLEERRRELEE 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 237 NthqvVEALEQETTAYKTEVAQLQLEQDARTKQLKEAETRFHAAKSVnekftdLQQKNERYNTLQENRAVIERKETSFRR 316
Cdd:COG1196 317 R----LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE------LAEAEEALLEAEAELAEAEEELEELAE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 317 AEQakhllpfeqwheEAMQNEQKAESLLKQIIVKKENiitsftLAQQKYEVEKNKELEREDAKKLVQRLEELQSIIASLA 396
Cdd:COG1196 387 ELL------------EALRAAAELAAQLEELEEAEEA------LLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 397 EKKLNLQNAEIQLGRLKESMQKLDQLLEEHTNQKQRMSGELQQLEQALEQYVAKVEELTNMREDAKVLKQAYDVWQEKQK 476
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 477 FEQEKEAAYTKMQEAVRAYENMERRWLSEQAGILALHLhdgescpvcgSTNHPKKATE-QSDAIDEKELNDLRDKKNVAE 555
Cdd:COG1196 529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL----------KAAKAGRATFlPLDKIRARAALAAALARGAIG 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 556 KLHVQVEEKWNFYRLQYEQVIEEVMKRGYHSDELVETYSALVQKGKQLAAEVNTLKESEETRKQIAVNIKSVEEKVDELQ 635
Cdd:COG1196 599 AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 636 KQKREAETLQHRTEMECMQLRTSYEHDKQNIPDNLQTVQAWKAQFDQAMQQLRLMEDewkkvQEAYQHWQNENIRIQAEH 715
Cdd:COG1196 679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE-----ELLEELLEEEELLEEEAL 753
|
570 580
....*....|....*....|....*..
gi 1263152438 716 EGASNQFESAKLKKE-ETLARFMKELE 741
Cdd:COG1196 754 EELPEPPDLEELERElERLEREIEALG 780
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
5-88 |
8.23e-07 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 50.05 E-value: 8.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 5 QLIMTAFGPYKQTEVINFddlGEHRIFAISGNTGAGKTTIFDAICYVLYGEASGEERSDTSMLRSQFAddnvYTSVELTF 84
Cdd:cd03227 1 KIVLGRFPSYFVPNDVTF---GEGSLTIITGPNGSGKSTILDAIGLALGGAQSATRRRSGVKAGCIVA----AVSAELIF 73
|
....
gi 1263152438 85 QLKG 88
Cdd:cd03227 74 TRLQ 77
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
281-507 |
1.73e-06 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 52.39 E-value: 1.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 281 KSVNEKFTDLQQKNERYNTLQENRAVI--ERKET---SFRRAEQAKHLLPFEQWHEEAMQNEQKAESLLKQIIVKKENII 355
Cdd:COG5022 813 RSYLACIIKLQKTIKREKKLRETEEVEfsLKAEVliqKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVK 892
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 356 TSFTLAQQKYE-----VEKNKELEREdakklvqRLEELQSIIASLAEKKLNLQNAEIQLGRLKEsMQKLDQLLEEHTnQK 430
Cdd:COG5022 893 SISSLKLVNLEleseiIELKKSLSSD-------LIENLEFKTELIARLKKLLNNIDLEEGPSIE-YVKLPELNKLHE-VE 963
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1263152438 431 QRMSGELQQLEQALEQYVAKVEELTNMREDAKVLKQAYDVWQEKQKFEQEKEAAYTKMQEAVRAYENMERRWLSEQA 507
Cdd:COG5022 964 SKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSEST 1040
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
189-461 |
2.52e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.60 E-value: 2.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 189 ELLDQKRKQWKDVLQEKQKERELHFRNVFKLPIRDGALLETLVEQEhvnthQVVEALEQETTAYKTEVAQLQLEQDARTK 268
Cdd:TIGR02168 694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE-----AEVEQLEERIAQLSKELTELEAEIEELEE 768
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 269 QLKEAETRFHAAKSVNEKFTDLQQKNERYNTLQENRAVIERKETSFRRAEQAKHLLPFEQWHEEAMQNEQKAESLLKQII 348
Cdd:TIGR02168 769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 349 VKKENIitsftlAQQKYEVEKNKELEREDAKKLVQRLEELQSIIASLAEKKLNLQNAEIQLGRLKESMQKLDQLLEEHTN 428
Cdd:TIGR02168 849 ELSEDI------ESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922
|
250 260 270
....*....|....*....|....*....|...
gi 1263152438 429 QKQRMSGELQQLEQALEQYVAKVEELTNMREDA 461
Cdd:TIGR02168 923 KLAQLELRLEGLEVRIDNLQERLSEEYSLTLEE 955
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
929-1023 |
3.60e-06 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 48.12 E-value: 3.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 929 VKTLSGGEKFNASLCLALGMADVIqayeggiSIETMFIDEGFGSLDEESLTKAVDALIDLQKSGRFIGVISHVQELKNAM 1008
Cdd:cd03227 75 RLQLSGGEKELSALALILALASLK-------PRPLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVIVITHLPELAELA 147
|
90
....*....|....*
gi 1263152438 1009 PAVLEVTKQKDGCSQ 1023
Cdd:cd03227 148 DKLIHIKKVITGVYK 162
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
344-687 |
3.84e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 3.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 344 LKQIIVKKENIITSFTLAQQKYEVEKNKELEREDAKKLVQRLEELQSIIASLAEKKLNLQNAEIQLGRLKESMQKLDQLL 423
Cdd:COG1196 218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 424 EEHTNQKQRMSGELQQLEQALEQYVAKVEELTNMREDAKvlkqaydvwQEKQKFEQEKEAAYTKMQEAVRAYENMERRWL 503
Cdd:COG1196 298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELE---------EELEELEEELEEAEEELEEAEAELAEAEEALL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 504 SEQAGILAlhlhdgescpvcgstnhpkkATEQSDAIDEKELNDLRDKKNVAEKLHVQVEEkwnfyrlqyEQVIEEVMKRg 583
Cdd:COG1196 369 EAEAELAE--------------------AEEELEELAEELLEALRAAAELAAQLEELEEA---------EEALLERLER- 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 584 yHSDELVETYSALVQKGKQLAAEVNTLKESEETRKQIAVNIKSVEEKVDELQKQKREAETLQHRTEMECMQLRTSYEHDK 663
Cdd:COG1196 419 -LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
330 340
....*....|....*....|....
gi 1263152438 664 QNIPDNLQTVQAWKAQFDQAMQQL 687
Cdd:COG1196 498 EAEADYEGFLEGVKAALLLAGLRG 521
|
|
| ABC_SMC_head |
cd03239 |
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural ... |
5-96 |
6.57e-06 |
|
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria, and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa, and each has five distinct domains: amino- and carboxy-terminal globular domains, which contain sequences characteristic of ATPases, two coiled-coil regions separating the terminal domains , and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions, including chromosome condensation, sister-chromatid cohesion, recombination, DNA repair, and epigenetic silencing of gene expression.
Pssm-ID: 213206 [Multi-domain] Cd Length: 178 Bit Score: 47.69 E-value: 6.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 5 QLIMTAFGPYKQTEVINfddlGEHRIFAISGNTGAGKTTIFDAICYVLYGEASGEERSDTSMLRSQFADDNVYT-SVELT 83
Cdd:cd03239 3 QITLKNFKSYRDETVVG----GSNSFNAIVGPNGSGKSNIVDAICFVLGGKAAKLRRGSLLFLAGGGVKAGINSaSVEIT 78
|
90
....*....|...
gi 1263152438 84 FQlkgKRYEIKRQ 96
Cdd:cd03239 79 FD---KSYFLVLQ 88
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
243-484 |
2.40e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 2.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 243 EALEQETTAYKTEVAQLQLEQDARTKQLKEAETRfhaaksVNEKFTDLQQKNERYNTLQENRAVIERKETSFRRAEQAkh 322
Cdd:COG4942 30 EQLQQEIAELEKELAALKKEEKALLKQLAALERR------IAALARRIRALEQELAALEAELAELEKEIAELRAELEA-- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 323 llpfeqwheeamQNEQKAESLLKQIIVKKENIITSFTLAQQKYEVEKNKELEREDAKKLVQRLEELQSIIASLAEKKLNL 402
Cdd:COG4942 102 ------------QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 403 QNAEIQLGRLKESMQKLDQLLEEHTNQKQRMSGELQQLEQALEQyvakveELTNMREDAKVLKQAYDVWQEKQKFEQEKE 482
Cdd:COG4942 170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAA------ELAELQQEAEELEALIARLEAEAAAAAERT 243
|
..
gi 1263152438 483 AA 484
Cdd:COG4942 244 PA 245
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
295-988 |
3.59e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 3.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 295 ERYNTLQENRAVIERKETSFRRA-EQAKHLLPFEQWHEEAMQNEQKAESLlkqiivkkENIITSFTL--AQQKYEVEKNK 371
Cdd:COG4913 225 EAADALVEHFDDLERAHEALEDArEQIELLEPIRELAERYAAARERLAEL--------EYLRAALRLwfAQRRLELLEAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 372 -ELEREDAKKLVQRLEELQSIIASLAEKKLNLQNA--EIQLGRLKEsmqkLDQLLEEHTNQKQRMSGELQQLEQALEQ-- 446
Cdd:COG4913 297 lEELRAELARLEAELERLEARLDALREELDELEAQirGNGGDRLEQ----LEREIERLERELEERERRRARLEALLAAlg 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 447 --YVAKVEELTNMREDAKVLKQAYDVWQEK-QKFEQEKEAAYTKMQEAVRAYENmERRWLSEQAGILALHLHDGescpvc 523
Cdd:COG4913 373 lpLPASAEEFAALRAEAAALLEALEEELEAlEEALAEAEAALRDLRRELRELEA-EIASLERRKSNIPARLLAL------ 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 524 gstnhpKKATEQSDAIDEKELN------DLRDK----KNVAEK-LHVQ-----VEEKW-----NFY-------RLQYEQV 575
Cdd:COG4913 446 ------RDALAEALGLDEAELPfvgeliEVRPEeerwRGAIERvLGGFaltllVPPEHyaaalRWVnrlhlrgRLVYERV 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 576 IEEVMKRGY---HSDELVE-------TYSALVQKgkQLAAE-----VNTLKESEETRKQIAVN----------------- 623
Cdd:COG4913 520 RTGLPDPERprlDPDSLAGkldfkphPFRAWLEA--ELGRRfdyvcVDSPEELRRHPRAITRAgqvkgngtrhekddrrr 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 624 --------------IKSVEEKVDELQKQKREAETLQHRTEMECMQLRTSYEH---------DKQNIPDNLQTVQAWKAQ- 679
Cdd:COG4913 598 irsryvlgfdnrakLAALEAELAELEEELAEAEERLEALEAELDALQERREAlqrlaeyswDEIDVASAEREIAELEAEl 677
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 680 --FDQAMQQLRLMEDEWKKVQEAYQHWQNENIRIQAEHEGASNQFESAKLKKEETLARF-----MKELEQRGFIDQLtYK 752
Cdd:COG4913 678 erLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLeaaedLARLELRALLEER-FA 756
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 753 EAKLNDAEMEM---LQKEIQSYYSSLEVLAKQIEELHAELKdKKF--------IDITSLGEHIKELE--INLDI----SK 815
Cdd:COG4913 757 AALGDAVERELrenLEERIDALRARLNRAEEELERAMRAFN-REWpaetadldADLESLPEYLALLDrlEEDGLpeyeER 835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 816 EKRQRAQNAVTYISDLHENIRRideqihEEEKAFQELVDLFEVMKgdnesRISF--ERYILIEYLEQIVQIANE---RLR 890
Cdd:COG4913 836 FKELLNENSIEFVADLLSKLRR------AIREIKERIDPLNDSLK-----RIPFgpGRYLRLEARPRPDPEVREfrqELR 904
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 891 KLSNG----------QFYLK--------RSERVEKRNRQSGLGLDV-----YDAY-----TGQT----RDVKTLSGGEKF 938
Cdd:COG4913 905 AVTSGaslfdeelseARFAAlkrlierlRSEEEESDRRWRARVLDVrnhleFDAEeidreDGEEvetySSSGGKSGGEKQ 984
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*..
gi 1263152438 939 N-------ASLCLALGMADviqayEGGISIETMFIDEGFGSLDEESLTKAVDALIDL 988
Cdd:COG4913 985 KlayfilaAALAYQLGLEG-----RGRPSFRTVVLDEAFSKMDEEFARRALRLFKEL 1036
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
18-60 |
8.52e-05 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 41.43 E-value: 8.52e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1263152438 18 EVIN---FD----DLGEHRIFAISGNTGAGKTTIFDAICYVLYG-------EASGEE 60
Cdd:pfam13555 5 QLINwgtFDghtiPIDPRGNTLLTGPSGSGKSTLLDAIQTLLVPakrarfnKAANAG 61
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
591-918 |
2.56e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 591 ETYSALVQKGKQLAAEVNTLKeseetRKQIAVNIKSVEEKVDELQKQKREAETLQHRTEMECMQLRTSYEHDKQNIPDNL 670
Cdd:COG1196 213 ERYRELKEELKELEAELLLLK-----LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 671 QTVQAWKAQFDQAMQQLRLMEDEWKKVQEAYQHWQNENIRIQAEHEGASNQFESAKLKKEEtlarfmKELEQRGFIDQLT 750
Cdd:COG1196 288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE------AEEELEEAEAELA 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 751 YKEAKLNDAEMEML--QKEIQSYYSSLEVLAKQIEELHAELKDKKFIDITSLGEHIKELEINLDISKEKRQRAQNAVTYI 828
Cdd:COG1196 362 EAEEALLEAEAELAeaEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 829 SDLHENIRRIDEQIHEEEKAFQELVDLFEVMKGDNEsrisfERYILIEYLEQIVQIANERLRKLSNGQFYLKRSERVEKR 908
Cdd:COG1196 442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEA-----ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516
|
330
....*....|
gi 1263152438 909 NRQSGLGLDV 918
Cdd:COG1196 517 AGLRGLAGAV 526
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
379-688 |
2.59e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.05 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 379 KKLVQRLEELQSiiaSLAEKKLNLQNAEIQLGRLKESMQKLDQLLEEHTNQKQRMSGELQQLEQALEQYVAKVEELTNMR 458
Cdd:TIGR02168 680 EELEEKIEELEE---KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 459 EDAKVLKQAYDvwQEKQKFEQEKEAAYTKMQEAVRAYENMERRWLSEQAGILALHlhdgescpvcgstnhpKKATEQSDA 538
Cdd:TIGR02168 757 TELEAEIEELE--ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR----------------AELTLLNEE 818
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 539 IDEKE--LNDLRDKKNVAEKLHVQVEEKWNFYRLQYEQVIEEVMKRGYHSDELVEtysALVQKGKQLAAEVNTLKESEET 616
Cdd:TIGR02168 819 AANLRerLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES---ELEALLNERASLEEALALLRSE 895
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1263152438 617 RKQIAVNIKSVEEKVDELQKQKREAETLQHRTEMECMQLrtsyehdkqnipdnlqtvqawKAQFDQAMQQLR 688
Cdd:TIGR02168 896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGL---------------------EVRIDNLQERLS 946
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
599-781 |
2.66e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 2.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 599 KGKQLAAEVNTLKESEETRKQIAVNIKSVEEKVDELQKQKREAETLQHRTEmECMQLRTSYEHDKQNIPD--NLQTVQAW 676
Cdd:COG4717 62 QGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELE-ELREELEKLEKLLQLLPLyqELEALEAE 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 677 KAQFDQAMQQLRLMEDEWKKVQEAYQHWQNENIRIQAEHEGASNQFESAKLKKEETLARFMKELEQRgfIDQLTyKEAKL 756
Cdd:COG4717 141 LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR--LAELE-EELEE 217
|
170 180
....*....|....*....|....*
gi 1263152438 757 NDAEMEMLQKEIQSYYSSLEVLAKQ 781
Cdd:COG4717 218 AQEELEELEEELEQLENELEAAALE 242
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
33-466 |
6.27e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.88 E-value: 6.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 33 ISGNTGAGKTTIFDAICYVLYGEASGEERSDTSMLRSQFADD-NVYTSVELTFQ-LKGKRYEIKRQL----GHKKQGNKT 106
Cdd:TIGR00606 33 LVGPNGAGKTTIIECLKYICTGDFPPGTKGNTFVHDPKVAQEtDVRAQIRLQFRdVNGEECAVVRSMvctqKTKKTEFKT 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 107 ITGHAVELydvMDGEKIPAVDRfhVTDVNKKVEDLIGLSKHQFSQIVMLPQGEFRKLLTSETENKEEiLRRIFKTDRYKL 186
Cdd:TIGR00606 113 LEGVITRY---KHGEKVSLSSK--CAEIDREMISHLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQK-FDEIFSATRYIK 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 187 MRELLDQKRKQWKDVLQEKQKERELHFRNVFKLP-IRDGAlleTLVEQEHVNTHQVVEALEQETTAYKTEVAQLQ----- 260
Cdd:TIGR00606 187 ALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACeIRDQI---TSKEAQLESSREIVKSYENELDPLKNRLKEIEhnlsk 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 261 -LEQDARTKQLKEAETRFHAAKSVNEKFTD--LQQKNERYNTLQENRAViERKETSFRRAEQAKHLLPFEQwhEEAMQNE 337
Cdd:TIGR00606 264 iMKLDNEIKALKSRKKQMEKDNSELELKMEkvFQGTDEQLNDLYHNHQR-TVREKERELVDCQRELEKLNK--ERRLLNQ 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 338 QKAESLLKQ------------IIVKKENIITSFTLAQQKYEVEKNKELERE--DAKKLVQRLEELQSIIAS--LAEKKLN 401
Cdd:TIGR00606 341 EKTELLVEQgrlqlqadrhqeHIRARDSLIQSLATRLELDGFERGPFSERQikNFHTLVIERQEDEAKTAAqlCADLQSK 420
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1263152438 402 LQNAEIQLGRLKESMQKLDQ-------LLEEHTNQKQRMSGELQQLEQALEQYVAKVEELTNMREDAKVLKQ 466
Cdd:TIGR00606 421 ERLKQEQADEIRDEKKGLGRtielkkeILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEK 492
|
|
| ABC_SMC2_euk |
cd03273 |
ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of ... |
1-52 |
7.18e-04 |
|
ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213240 [Multi-domain] Cd Length: 251 Bit Score: 42.67 E-value: 7.18e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1263152438 1 MRPIQLIMTAFGPY-KQTEVINFDDLgehriF-AISGNTGAGKTTIFDAICYVL 52
Cdd:cd03273 1 MHIKEIILDGFKSYaTRTVISGFDPQ-----FnAITGLNGSGKSNILDAICFVL 49
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
239-720 |
1.31e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.73 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 239 HQVVEALEQETTAYKTEVAQLQLEQDARTKQLKE----AETRFHAAKSVNEKFTDLQQKNERYNT-LQENRAVIERKETS 313
Cdd:TIGR00606 694 QEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEmlglAPGRQSIIDLKEKEIPELRNKLQKVNRdIQRLKNDIEEQETL 773
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 314 FR----RAEQAKHLLP----FEQWHEEAMQNEQKAESLLKQIivkkeniiTSFTLAQQKYEVEKNKELEREDAKKLVQRL 385
Cdd:TIGR00606 774 LGtimpEEESAKVCLTdvtiMERFQMELKDVERKIAQQAAKL--------QGSDLDRTVQQVNQEKQEKQHELDTVVSKI 845
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 386 EELQSIIASLAEKKLNLQNAEIQLGRLKESMQkldqlleehTNQKQRmsgelQQLEQALEQYVAKVEELTNMREDAKvlK 465
Cdd:TIGR00606 846 ELNRKLIQDQQEQIQHLKSKTNELKSEKLQIG---------TNLQRR-----QQFEEQLVELSTEVQSLIREIKDAK--E 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 466 QAYDVWQEKQKFEQEKEAAYTKMQEAVRAYEnMERRWLSEQAGILALHLHDGEscpvcgstnhpkkateqsDAIDEKELN 545
Cdd:TIGR00606 910 QDSPLETFLEKDQQEKEELISSKETSNKKAQ-DKVNDIKEKVKNIHGYMKDIE------------------NKIQDGKDD 970
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 546 DLRDKKNVAEKLHVQVEEKWnfyrlQYEQVIEEVMKRGYHSDELVETYSALVQKGKQLAAEVNTLKESEETRKQI--AVN 623
Cdd:TIGR00606 971 YLKQKETELNTVNAQLEECE-----KHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHlkEMG 1045
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 624 IKSVEEKVDELQKQKREAETLQhRTEMECMQLRTSYEHDKQNIPDNLQTVQAWKAQ--FDQAMQQLRLMEDEWKKVQEAY 701
Cdd:TIGR00606 1046 QMQVLQMKQEHQKLEENIDLIK-RNHVLALGRQKGYEKEIKHFKKELREPQFRDAEekYREMMIVMRTTELVNKDLDIYY 1124
|
490
....*....|....*....
gi 1263152438 702 QHWQNENIRIQAEHEGASN 720
Cdd:TIGR00606 1125 KTLDQAIMKFHSMKMEEIN 1143
|
|
| DNA_S_dndD |
TIGR03185 |
DNA sulfur modification protein DndD; This model describes the DndB protein encoded by an ... |
5-431 |
1.32e-03 |
|
DNA sulfur modification protein DndD; This model describes the DndB protein encoded by an operon associated with a sulfur-containing modification to DNA. The operon is sporadically distributed in bacteria, much like some restriction enzyme operons. DndD is described as a putative ATPase. The small number of examples known so far include species from among the Firmicutes, Actinomycetes, Proteobacteria, and Cyanobacteria. [DNA metabolism, Restriction/modification]
Pssm-ID: 274475 [Multi-domain] Cd Length: 650 Bit Score: 42.75 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 5 QLIMTAFGPYKQTEVINFDDLGEHRIFAISGNTGAGKTTIFDAICYVLYG-EASGEERSD-------TSMLRSQFADDNV 76
Cdd:TIGR03185 5 QLTLENFGPYRGRQTFDLSPSSPKPIILIGGLNGAGKTTLLDAIQLALYGkRALCSGRGNksyeqylRGLINRQAGKTNP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 77 yTSVELTFQLKGKRYEIKRQLGHKKQGNKTITGHAVELYdvmdgekipaVDRFHVTDVNKKVEDLI-GLSKHQFSQIVML 155
Cdd:TIGR03185 85 -ASITLTFSVVEGGKRHEYTLVRSWHINNKDVKEKLTVY----------KDDEEDDSLNDIWDEFInELLPLELADLFFF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 156 pQGEFRKLLTSETENKEEILRRIFKTdrykLMRELLDQKRKQWKDVLQEKQKErelhfrnvfKLPIRDGALLETLvEQEH 235
Cdd:TIGR03185 154 -DGEKIEALANPDRLASLLKEAIEVL----LGLDLIDRLAGDLTNVLRRRKKS---------ELPSSILSEIEAL-EAEL 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 236 VNTHQVVEALEQETTAYKTEVAQLQ-----LEQDARTKQLKEAETRFHAAKSVNEKFTDLQQKNERYNTLQE-------N 303
Cdd:TIGR03185 219 KEQSEKYEDLAQEIAHLRNELEEAQrslesLEKKFRSEGGDLFEEREQLERQLKEIEAARKANRAQLRELAAdplplllI 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 304 RAVIERKETSFRRAEQAKH-------LLPFEQWHEEAMQNEQKAESLLKQI----------------------------- 347
Cdd:TIGR03185 299 PNLLDSTKAQLQKEEQSQQnqltqeeLEERDKELLESLPKLALPAEHVKEIaaelaeidkpattdseiphrlsgseltql 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 348 -----IVKKENIITSFTLAQQKYEVEK-----NKELEREDAKKLVQRL-EELQSIIASLAEKKLNLQNAEIQLGRLKESM 416
Cdd:TIGR03185 379 evliqQVKRELQDAKSQLLKELRELEEelaevDKKISTIPSEEQIAQLlEELGEAQNELFRSEAEIEELLRQLETLKEAI 458
|
490
....*....|....*
gi 1263152438 417 QKLDQLLEEHTNQKQ 431
Cdd:TIGR03185 459 EALRKTLDEKTKQKI 473
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
337-462 |
1.49e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 337 EQKAESLLKQIivKKE-NIITSFTLAQQKYEVEKNK-ELEREdakkLVQRLEELQSIIASLAEKKLNLQNaeiQLGRLKE 414
Cdd:PRK12704 37 EEEAKRILEEA--KKEaEAIKKEALLEAKEEIHKLRnEFEKE----LRERRNELQKLEKRLLQKEENLDR---KLELLEK 107
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1263152438 415 SMQKLDQLLEEHTNQKQRMSGELQQLEQALEQYVAKVEELTNM-REDAK 462
Cdd:PRK12704 108 REEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLtAEEAK 156
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
375-611 |
1.83e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.25 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 375 REDAKKLVQRLEELQSIIASLAEKKLNLQN----AEIQLGRLKESM----QKLD-------------QLLEEHTNQKQRM 433
Cdd:PRK04863 354 QADLEELEERLEEQNEVVEEADEQQEENEAraeaAEEEVDELKSQLadyqQALDvqqtraiqyqqavQALERAKQLCGLP 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 434 SGELQQLEQALEQYVAKVEELTNMREDakvLKQAYDVWQE-KQKFEQ------------EKEAAYTKMQEAVRAYEnmER 500
Cdd:PRK04863 434 DLTADNAEDWLEEFQAKEQEATEELLS---LEQKLSVAQAaHSQFEQayqlvrkiagevSRSEAWDVARELLRRLR--EQ 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 501 RWLSEQAGILALHLHDGEscpvcgstnhpKKATEQSDAidekelNDLRDKKNVAEKLHVQVEEKWNFYRLQYEQVIEEvm 580
Cdd:PRK04863 509 RHLAEQLQQLRMRLSELE-----------QRLRQQQRA------ERLLAEFCKRLGKNLDDEDELEQLQEELEARLES-- 569
|
250 260 270
....*....|....*....|....*....|....
gi 1263152438 581 krgyHSDEL---VETYSALVQKGKQLAAEVNTLK 611
Cdd:PRK04863 570 ----LSESVseaRERRMALRQQLEQLQARIQRLA 599
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
591-852 |
2.19e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 2.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 591 ETYSALvQKGKQLAAEVNTLKESEETRKQIAVNIKSVEEKVDELQKQKREAETLQHRTEMECMQLRTSYEHDKQNIPDNL 670
Cdd:TIGR02169 211 ERYQAL-LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 671 QTVQA----WKAQFDQAMQQLRLMEDEWKKVQEAYQHWQNENIRIQAEHEGASNQFESAKLKKEETLARF------MKEL 740
Cdd:TIGR02169 290 LRVKEkigeLEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYaelkeeLEDL 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 741 EQR---------GFIDQLTYKEAKLNDA--EMEMLQKEIQSYYSSLEVLAKQIEELHAELKDKK------FIDITSLGEH 803
Cdd:TIGR02169 370 RAEleevdkefaETRDELKDYREKLEKLkrEINELKRELDRLQEELQRLSEELADLNAAIAGIEakinelEEEKEDKALE 449
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1263152438 804 IKELEINLDISKEKRQRAQNAvtyISDLHENIRRIDEQIHEEEKAFQEL 852
Cdd:TIGR02169 450 IKKQEWKLEQLAADLSKYEQE---LYDLKEEYDRVEKELSKLQRELAEA 495
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
295-702 |
2.23e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.06 E-value: 2.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 295 ERYNTLQENRAVIERKETSFRRAEQAKHLLpfeqwhEEAMQNEQKAESLLKQIIVKKENIITSFTLAQQKYEVEKNKELE 374
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEEL------EEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAEL 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 375 REDAKKLVQRLEELQSIIASLAEKKLNLQNAEIQLGRLKESM-QKLDQLLEEHTNQKQRMSGELQQLEQALEQYVAKVEE 453
Cdd:COG4717 145 PERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 454 LtnmREDAKVLKQAYDVWQEKQKFEQEKE---------AAYTKMQEAVRAYENMERRWLSEQAGILALHLHDGESCPVCG 524
Cdd:COG4717 225 L---EEELEQLENELEAAALEERLKEARLllliaaallALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 525 STNHPKKATEQSDAIDEKELNDLRDKKNVAEKLHV--------------QVEEKWN-----FYRLQYEQVIEEVMKRG-- 583
Cdd:COG4717 302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPeellelldrieelqELLREAEeleeeLQLEELEQEIAALLAEAgv 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 584 ------YHSDELVETYSALVQKGKQL-------------AAEVNTLKESEETRKQIAVNIKSVEEKVDELQKQKREAETL 644
Cdd:COG4717 382 edeeelRAALEQAEEYQELKEELEELeeqleellgeleeLLEALDEEELEEELEELEEELEELEEELEELREELAELEAE 461
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1263152438 645 QHRTEmecmqlrtsyehdkqnipdNLQTVQAWKAQFDQAMQQLRLMEDEWKKVQEAYQ 702
Cdd:COG4717 462 LEQLE-------------------EDGELAELLQELEELKAELRELAEEWAALKLALE 500
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
169-439 |
2.36e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.13 E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 169 ENKEEILRRIF---KTDRYKLMRELLDQKRKQWKDVLQ-EKQKERELHFRNVFKLPIRDGALLETLVEQEHVntHQVVEA 244
Cdd:pfam12128 649 KNARLDLRRLFdekQSEKDKKNKALAERKDSANERLNSlEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYW--QVVEGA 726
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 245 LEQETTAYKTEVAQLQLEQDARTKQLKEAETRFHAAKSVNE-KFTDLQQKNERYNTLQENRAVIERKETSFRRAEQAKHL 323
Cdd:pfam12128 727 LDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPdVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWL 806
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 324 LPFEQWHEEAMQNEQKAESLLKQIIVKKENIITsftlaqQKYEVEKNKELEREDAKKLVQRLEELQSIIASLAEKKLNLQ 403
Cdd:pfam12128 807 QRRPRLATQLSNIERAISELQQQLARLIADTKL------RRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDAN 880
|
250 260 270
....*....|....*....|....*....|....*.
gi 1263152438 404 NAEIQlGRLKESMQKLDQLLEEHtnqkQRMSGELQQ 439
Cdd:pfam12128 881 SEQAQ-GSIGERLAQLEDLKLKR----DYLSESVKK 911
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
364-481 |
4.69e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 40.39 E-value: 4.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 364 KYEVEKNKELEREDAKKLVQRLEELQSIIASLAEKKLNLQNAEIQLGRLKESMQKLDQllEEHTNQKQRMSGELQQLE-- 441
Cdd:smart00787 146 KEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDP--TELDRAKEKLKKLLQEIMik 223
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1263152438 442 -QALEQYVAKVEELTNMREDAKVLKQAY--DVWQEKQKFEQEK 481
Cdd:smart00787 224 vKKLEELEEELQELESKIEDLTNKKSELntEIAEAEKKLEQCR 266
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
677-874 |
6.08e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 40.40 E-value: 6.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 677 KAQFDQAMQQLRLMEDEWKKVQEAYQhwqneniriQAEHEGASNQFESAKLKKEETLARFMKELeqrgfidqltykeakL 756
Cdd:pfam05667 341 QEQLEDLESSIQELEKEIKKLESSIK---------QVEEELEELKEQNEELEKQYKVKKKTLDL---------------L 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 757 NDAE--MEMLQKEIQSYYSSLEVLAKQIEELHAELkdkkfiditslgehIKELEINLDISKEKRQRAQNAVTYISDLHEN 834
Cdd:pfam05667 397 PDAEenIAKLQALVDASAQRLVELAGQWEKHRVPL--------------IEEYRALKEAKSNKEDESQRKLEEIKELREK 462
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1263152438 835 IRRIDEQIHEEEKAFQELVDLFEVMKGDnESRISFERYIL 874
Cdd:pfam05667 463 IKEVAEEAKQKEELYKQLVAEYERLPKD-VSRSAYTRRIL 501
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
932-1004 |
7.30e-03 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 38.38 E-value: 7.30e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1263152438 932 LSGGEKFNASLCLALGMADVIqayeggisietMFIDEGFGSLDEESLTKAVDALIDLQKSGRFIGVISHVQEL 1004
Cdd:cd00267 81 LSGGQRQRVALARALLLNPDL-----------LLLDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPEL 142
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
376-497 |
7.34e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 40.20 E-value: 7.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 376 EDAKKLV-QRLEELQSIIASLAEKKLNLQNAEIQLGRLKESMQKLDQLLEEhtnQKQRMSGELQQLEQALEQ-YVAKVEE 453
Cdd:PRK00409 505 EEAKKLIgEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEE---KKEKLQEEEDKLLEEAEKeAQQAIKE 581
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1263152438 454 LtnMREDAKVLKQAYDVWQEKQKFEQEKEA--AYTKMQEAVRAYEN 497
Cdd:PRK00409 582 A--KKEADEIIKELRQLQKGGYASVKAHELieARKRLNKANEKKEK 625
|
|
| ABC_SMC_barmotin |
cd03278 |
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ... |
19-96 |
8.27e-03 |
|
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213245 [Multi-domain] Cd Length: 197 Bit Score: 38.60 E-value: 8.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 19 VINFDDlgehRIFAISGNTGAGKTTIFDAICYVLyGEAS-----GEERSDTSMLRSQFADDNVYTSVELTFQLKGKRYEI 93
Cdd:cd03278 17 TIPFPP----GLTAIVGPNGSGKSNIIDAIRWVL-GEQSakslrGEKMSDVIFAGSETRKPANFAEVTLTFDNSDGRYSI 91
|
...
gi 1263152438 94 KRQ 96
Cdd:cd03278 92 ISQ 94
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
374-643 |
8.56e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.05 E-value: 8.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 374 EREDAKKLVQRLEELQSIIASLAEKklnlqnaeiqLGRLKESMQKLDQLLEEHTNQKQRMSGELQQLEQALEQYvakVEE 453
Cdd:TIGR02169 672 EPAELQRLRERLEGLKRELSSLQSE----------LRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL---KER 738
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 454 LTNMREDAKVLKQAY-DVWQEKQKFE---QEKEAAYTKMQEAVrayENMERRWLSEQAGILALHLHDGEscpvcgstnhp 529
Cdd:TIGR02169 739 LEELEEDLSSLEQEIeNVKSELKELEariEELEEDLHKLEEAL---NDLEARLSHSRIPEIQAELSKLE----------- 804
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 530 KKATEQSDAID--EKELNDLRDKKNVAEKLHVQVEEKWNFYRLQYEQVIEEVmkrgyhsDELVETYSALVQKGKQLAAEV 607
Cdd:TIGR02169 805 EEVSRIEARLReiEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEI-------ENLNGKKEELEEELEELEAAL 877
|
250 260 270
....*....|....*....|....*....|....*.
gi 1263152438 608 NTLkesEETRKQIAVNIKSVEEKVDELQKQKREAET 643
Cdd:TIGR02169 878 RDL---ESRLGDLKKERDELEAQLRELERKIEELEA 910
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
251-455 |
8.93e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 40.32 E-value: 8.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 251 AYKTEVAQLQLEqdARTKQLKEAETRFHAA----KSVNEKFTDLQQKNEryntLQENRAVIERKetSFRRAEQAKHLLP- 325
Cdd:COG3096 360 TERLEEQEEVVE--EAAEQLAEAEARLEAAeeevDSLKSQLADYQQALD----VQQTRAIQYQQ--AVQALEKARALCGl 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 326 -------FEQWHEEAMQNEQKA-ESLL--KQIIVKKENIITSFtlaQQKYE-VEK-NKELEREDA--------------K 379
Cdd:COG3096 432 pdltpenAEDYLAAFRAKEQQAtEEVLelEQKLSVADAARRQF---EKAYElVCKiAGEVERSQAwqtarellrryrsqQ 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1263152438 380 KLVQRLEELQSIIASLAEKKLNLQNAEIQLGR--------------LKESMQKLDQLLEEHTNQKQRMSGELQQLEQALE 445
Cdd:COG3096 509 ALAQRLQQLRAQLAELEQRLRQQQNAERLLEEfcqrigqqldaaeeLEELLAELEAQLEELEEQAAEAVEQRSELRQQLE 588
|
250
....*....|
gi 1263152438 446 QYVAKVEELT 455
Cdd:COG3096 589 QLRARIKELA 598
|
|
| |
