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Conserved domains on  [gi|1264956977|gb|PGO90592|]
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lineage-specific thermal regulator protein [Bacillus thuringiensis]

Protein Classification

MarR family transcriptional regulator; GntR family transcriptional regulator( domain architecture ID 10013224)

MarR family transcriptional regulator such as the multiple antibiotic resistance transcriptional regulator MarR, the repressor of the marRAB operon involved in the activation of both antibiotic resistance and oxidative stress genes| GntR-family transcriptional regulator is one of a group of transcriptional regulators with a conserved N-terminal helix-turn-helix DNA-binding domain and a diverse C-terminal effector-binding and oligomerization domain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
lstR PRK09416
PadR family transcriptional regulator;
1-135 3.02e-64

PadR family transcriptional regulator;


:

Pssm-ID: 181836  Cd Length: 135  Bit Score: 191.93  E-value: 3.02e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956977   1 MEDRLKGLRKSMENTTFKHLSFSDQHQKRVREKINQSSEKEEDILLAVLQLIMNEKTGYELMQLMRGRGIQKFEGDEGSL 80
Cdd:PRK09416    1 MEDRLKGLKKSMDNTTFKHLSFSEQHQKAVREKIKQSSEKEEDILLAILQLLMNEKTGYELLQLLRQRGILTFEGNEGSL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1264956977  81 YTLLHRLEQNRFIQSSWDHAGAKYYQLNDKGNKMLRKAEKNATKARFILKGLVQE 135
Cdd:PRK09416   81 YTLLHRLEQNRFIQSSWDHEGAKYYQLTDKGNKMLRKAEKNATKARFILKGLVQE 135
 
Name Accession Description Interval E-value
lstR PRK09416
PadR family transcriptional regulator;
1-135 3.02e-64

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 191.93  E-value: 3.02e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956977   1 MEDRLKGLRKSMENTTFKHLSFSDQHQKRVREKINQSSEKEEDILLAVLQLIMNEKTGYELMQLMRGRGIQKFEGDEGSL 80
Cdd:PRK09416    1 MEDRLKGLKKSMDNTTFKHLSFSEQHQKAVREKIKQSSEKEEDILLAILQLLMNEKTGYELLQLLRQRGILTFEGNEGSL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1264956977  81 YTLLHRLEQNRFIQSSWDHAGAKYYQLNDKGNKMLRKAEKNATKARFILKGLVQE 135
Cdd:PRK09416   81 YTLLHRLEQNRFIQSSWDHEGAKYYQLTDKGNKMLRKAEKNATKARFILKGLVQE 135
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
46-118 1.24e-13

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 62.26  E-value: 1.24e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1264956977  46 LAVLQLIMNE-KTGYELMQLMRGRGIQKFEGDEGSLYTLLHRLEQNRFIQSSWDHAGA----KYYQLNDKGNKMLRKA 118
Cdd:COG1695    12 LLILALLAEGpMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEESEGgprrKYYRLTEAGREELAEW 89
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 45-116 1.31e-10

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 53.79  E-value: 1.31e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1264956977  45 LLAVLQLimNEKTGYELMQLMRGRGIQKFEGDEGSLYTLLHRLEQNRFIQSSWDHAGA----KYYQLNDKGNKMLR 116
Cdd:pfam03551   1 VLAVLGE--QPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVESEWVDSGGgpprKYYRLTDAGRRELA 74
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 58-116 3.68e-08

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 47.94  E-value: 3.68e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1264956977  58 GYELMQLMRGRGIQKFEGDEGSLYTLLHRLEQNRFIQSSW----DHAGAKYYQLNDKGNKMLR 116
Cdd:TIGR03433  20 GYGIAQRIQQISEDVLQVEEGSLYPALHRLERRGWIAAEWgeseNNRRAKFYRLTAAGRKQLA 82
 
Name Accession Description Interval E-value
lstR PRK09416
PadR family transcriptional regulator;
1-135 3.02e-64

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 191.93  E-value: 3.02e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956977   1 MEDRLKGLRKSMENTTFKHLSFSDQHQKRVREKINQSSEKEEDILLAVLQLIMNEKTGYELMQLMRGRGIQKFEGDEGSL 80
Cdd:PRK09416    1 MEDRLKGLKKSMDNTTFKHLSFSEQHQKAVREKIKQSSEKEEDILLAILQLLMNEKTGYELLQLLRQRGILTFEGNEGSL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1264956977  81 YTLLHRLEQNRFIQSSWDHAGAKYYQLNDKGNKMLRKAEKNATKARFILKGLVQE 135
Cdd:PRK09416   81 YTLLHRLEQNRFIQSSWDHEGAKYYQLTDKGNKMLRKAEKNATKARFILKGLVQE 135
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
46-118 1.24e-13

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 62.26  E-value: 1.24e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1264956977  46 LAVLQLIMNE-KTGYELMQLMRGRGIQKFEGDEGSLYTLLHRLEQNRFIQSSWDHAGA----KYYQLNDKGNKMLRKA 118
Cdd:COG1695    12 LLILALLAEGpMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVESEWEESEGgprrKYYRLTEAGREELAEW 89
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 45-116 1.31e-10

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 53.79  E-value: 1.31e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1264956977  45 LLAVLQLimNEKTGYELMQLMRGRGIQKFEGDEGSLYTLLHRLEQNRFIQSSWDHAGA----KYYQLNDKGNKMLR 116
Cdd:pfam03551   1 VLAVLGE--QPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVESEWVDSGGgpprKYYRLTDAGRRELA 74
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 58-116 3.68e-08

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 47.94  E-value: 3.68e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1264956977  58 GYELMQLMRGRGIQKFEGDEGSLYTLLHRLEQNRFIQSSW----DHAGAKYYQLNDKGNKMLR 116
Cdd:TIGR03433  20 GYGIAQRIQQISEDVLQVEEGSLYPALHRLERRGWIAAEWgeseNNRRAKFYRLTAAGRKQLA 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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