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Conserved domains on  [gi|1264956978|gb|PGO90593|]
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transposase [Bacillus thuringiensis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tspaseT_teng_C TIGR01766
transposase, IS605 OrfB family, central region; This model represents a region of a sequence ...
 330-410 6.24e-17

transposase, IS605 OrfB family, central region; This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions]


:

Pssm-ID: 273793 [Multi-domain]  Cd Length: 82  Bit Score: 75.45  E-value: 6.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 330 STNKRGTIIGQIVQQIKTWLLENNvGGIVLEDL-QFQQSHD-TDKYSNRNFHQFTYKKMLNNLIRMALRNGLSVKTVNPA 407
Cdd:TIGR01766   1 ERNKVEDFLHKIVKQIVEYAKENN-GTIVLEDLkNIREMVDkKSKYLRRKLHQWSFRKLISKIKYKAEEYGIEVIEVNPA 79


                  ...
gi 1264956978 408 YTS 410
Cdd:TIGR01766  80 YTS 82
tspaseT_teng_N super family cl12223
transposase, putative, N-terminal domain; This model represents the N-terminal region of a ...
 4-79 8.33e-15

transposase, putative, N-terminal domain; This model represents the N-terminal region of a family of putative transposases found in the largest copy number in Thermoanaerobacter tengcongensis. The three homologs in Bacillus anthracis are each split into two ORFs and this model represents the upstream ORF. [Mobile and extrachromosomal element functions, Transposon functions]


The actual alignment was detected with superfamily member TIGR01765:

Pssm-ID: 130826  Cd Length: 73  Bit Score: 69.35  E-value: 8.33e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1264956978   4 TRACKIGSITKEQtEDLITLIRTFESAKRYSLNRLIDGENEKELIKKLQPKYLLNkrFCEDAVLQAQTILSSQKEL 79
Cdd:TIGR01765   1 TIKAKLNFEDKEK-EYLLDLIRAFSSAVNFVIKRLLEGKSHSELKKELQRLYYLN--YREDAPLQAQSLIQGAREL 73
guided_TnpB super family cl45887
RNA-guided endonuclease TnpB family protein; This family includes RNA-guided endonuclease TnpB ...
 210-420 6.27e-10

RNA-guided endonuclease TnpB family protein; This family includes RNA-guided endonuclease TnpB from IS200/IS605 family elements (NF038281) and IS607 family elements (NF038280), but also many additional proteins. It exhibits homolog to or actually includes some CRISPR-associated (Cas) proteins such as the type V CRISPR-associated protein C2c8. For a long time, TnpB proteins were described as accessory proteins in IS (insertion sequence) elements, present as one of just one or two proteins encoded in the element but not necessary for transposition. The programmable RNA-guided endonuclease TnpB proteins may provide a CRISPR-like, widespread form of phage defense by RNA-guided DNA degradation.


The actual alignment was detected with superfamily member NF040570:

Pssm-ID: 468544 [Multi-domain]  Cd Length: 384  Bit Score: 61.02  E-value: 6.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 210 TNGKTKSPRIKVPIIIPYRFY-HQITNVVMGEKIDVNpkgkpmiehqKYSVEIIRKQSEFYVNITFDETEIgrvlEFKET 288
Cdd:NF040570  123 RNRKKKNGRLKLPKLGGVKLRlSRILPILLDGKGGKI----------KSVTISKPKKGKYYVSISVEVEVP----EPPPK 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 289 PQSDVMAGIDVNPDRIAV--------------------------------SLCTKQGNFKDSKIFYLHNLNTFSTNKRGT 336
Cdd:NF040570  189 EVTGKVVGIDLGLKNFATlsdggekienprflrkkekrlrrlqrklsrklQRKGKGSSNRKKARKKVARLHRKIANQRKD 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 337 IIGQIVQQIKTWLLENNVGGIVLEDLQFQQSHdTDKYSNRNFHQFTYKKMLNNLIRMALRNGLSVKTVNPAYTSVIGKLK 416
Cdd:NF040570  269 FLHKLSKRLVKEADANNVVVEDLEVKGMVKNK-KKKKLAKSIHDWAFGQLRRMLEYKAEWYGIKVVKVDPAYTSSQCCSC 347


                  ....
gi 1264956978 417 YSKK 420
Cdd:NF040570  348 GGHR 351
 
Name Accession Description Interval E-value
tspaseT_teng_C TIGR01766
transposase, IS605 OrfB family, central region; This model represents a region of a sequence ...
 330-410 6.24e-17

transposase, IS605 OrfB family, central region; This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions]


Pssm-ID: 273793 [Multi-domain]  Cd Length: 82  Bit Score: 75.45  E-value: 6.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 330 STNKRGTIIGQIVQQIKTWLLENNvGGIVLEDL-QFQQSHD-TDKYSNRNFHQFTYKKMLNNLIRMALRNGLSVKTVNPA 407
Cdd:TIGR01766   1 ERNKVEDFLHKIVKQIVEYAKENN-GTIVLEDLkNIREMVDkKSKYLRRKLHQWSFRKLISKIKYKAEEYGIEVIEVNPA 79


                  ...
gi 1264956978 408 YTS 410
Cdd:TIGR01766  80 YTS 82
tspaseT_teng_N TIGR01765
transposase, putative, N-terminal domain; This model represents the N-terminal region of a ...
 4-79 8.33e-15

transposase, putative, N-terminal domain; This model represents the N-terminal region of a family of putative transposases found in the largest copy number in Thermoanaerobacter tengcongensis. The three homologs in Bacillus anthracis are each split into two ORFs and this model represents the upstream ORF. [Mobile and extrachromosomal element functions, Transposon functions]


Pssm-ID: 130826  Cd Length: 73  Bit Score: 69.35  E-value: 8.33e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1264956978   4 TRACKIGSITKEQtEDLITLIRTFESAKRYSLNRLIDGENEKELIKKLQPKYLLNkrFCEDAVLQAQTILSSQKEL 79
Cdd:TIGR01765   1 TIKAKLNFEDKEK-EYLLDLIRAFSSAVNFVIKRLLEGKSHSELKKELQRLYYLN--YREDAPLQAQSLIQGAREL 73
guided_TnpB NF040570
RNA-guided endonuclease TnpB family protein; This family includes RNA-guided endonuclease TnpB ...
 210-420 6.27e-10

RNA-guided endonuclease TnpB family protein; This family includes RNA-guided endonuclease TnpB from IS200/IS605 family elements (NF038281) and IS607 family elements (NF038280), but also many additional proteins. It exhibits homolog to or actually includes some CRISPR-associated (Cas) proteins such as the type V CRISPR-associated protein C2c8. For a long time, TnpB proteins were described as accessory proteins in IS (insertion sequence) elements, present as one of just one or two proteins encoded in the element but not necessary for transposition. The programmable RNA-guided endonuclease TnpB proteins may provide a CRISPR-like, widespread form of phage defense by RNA-guided DNA degradation.


Pssm-ID: 468544 [Multi-domain]  Cd Length: 384  Bit Score: 61.02  E-value: 6.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 210 TNGKTKSPRIKVPIIIPYRFY-HQITNVVMGEKIDVNpkgkpmiehqKYSVEIIRKQSEFYVNITFDETEIgrvlEFKET 288
Cdd:NF040570  123 RNRKKKNGRLKLPKLGGVKLRlSRILPILLDGKGGKI----------KSVTISKPKKGKYYVSISVEVEVP----EPPPK 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 289 PQSDVMAGIDVNPDRIAV--------------------------------SLCTKQGNFKDSKIFYLHNLNTFSTNKRGT 336
Cdd:NF040570  189 EVTGKVVGIDLGLKNFATlsdggekienprflrkkekrlrrlqrklsrklQRKGKGSSNRKKARKKVARLHRKIANQRKD 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 337 IIGQIVQQIKTWLLENNVGGIVLEDLQFQQSHdTDKYSNRNFHQFTYKKMLNNLIRMALRNGLSVKTVNPAYTSVIGKLK 416
Cdd:NF040570  269 FLHKLSKRLVKEADANNVVVEDLEVKGMVKNK-KKKKLAKSIHDWAFGQLRRMLEYKAEWYGIKVVKVDPAYTSSQCCSC 347


                  ....
gi 1264956978 417 YSKK 420
Cdd:NF040570  348 GGHR 351
 
Name Accession Description Interval E-value
tspaseT_teng_C TIGR01766
transposase, IS605 OrfB family, central region; This model represents a region of a sequence ...
 330-410 6.24e-17

transposase, IS605 OrfB family, central region; This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions]


Pssm-ID: 273793 [Multi-domain]  Cd Length: 82  Bit Score: 75.45  E-value: 6.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 330 STNKRGTIIGQIVQQIKTWLLENNvGGIVLEDL-QFQQSHD-TDKYSNRNFHQFTYKKMLNNLIRMALRNGLSVKTVNPA 407
Cdd:TIGR01766   1 ERNKVEDFLHKIVKQIVEYAKENN-GTIVLEDLkNIREMVDkKSKYLRRKLHQWSFRKLISKIKYKAEEYGIEVIEVNPA 79


                  ...
gi 1264956978 408 YTS 410
Cdd:TIGR01766  80 YTS 82
tspaseT_teng_N TIGR01765
transposase, putative, N-terminal domain; This model represents the N-terminal region of a ...
 4-79 8.33e-15

transposase, putative, N-terminal domain; This model represents the N-terminal region of a family of putative transposases found in the largest copy number in Thermoanaerobacter tengcongensis. The three homologs in Bacillus anthracis are each split into two ORFs and this model represents the upstream ORF. [Mobile and extrachromosomal element functions, Transposon functions]


Pssm-ID: 130826  Cd Length: 73  Bit Score: 69.35  E-value: 8.33e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1264956978   4 TRACKIGSITKEQtEDLITLIRTFESAKRYSLNRLIDGENEKELIKKLQPKYLLNkrFCEDAVLQAQTILSSQKEL 79
Cdd:TIGR01765   1 TIKAKLNFEDKEK-EYLLDLIRAFSSAVNFVIKRLLEGKSHSELKKELQRLYYLN--YREDAPLQAQSLIQGAREL 73
guided_TnpB NF040570
RNA-guided endonuclease TnpB family protein; This family includes RNA-guided endonuclease TnpB ...
 210-420 6.27e-10

RNA-guided endonuclease TnpB family protein; This family includes RNA-guided endonuclease TnpB from IS200/IS605 family elements (NF038281) and IS607 family elements (NF038280), but also many additional proteins. It exhibits homolog to or actually includes some CRISPR-associated (Cas) proteins such as the type V CRISPR-associated protein C2c8. For a long time, TnpB proteins were described as accessory proteins in IS (insertion sequence) elements, present as one of just one or two proteins encoded in the element but not necessary for transposition. The programmable RNA-guided endonuclease TnpB proteins may provide a CRISPR-like, widespread form of phage defense by RNA-guided DNA degradation.


Pssm-ID: 468544 [Multi-domain]  Cd Length: 384  Bit Score: 61.02  E-value: 6.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 210 TNGKTKSPRIKVPIIIPYRFY-HQITNVVMGEKIDVNpkgkpmiehqKYSVEIIRKQSEFYVNITFDETEIgrvlEFKET 288
Cdd:NF040570  123 RNRKKKNGRLKLPKLGGVKLRlSRILPILLDGKGGKI----------KSVTISKPKKGKYYVSISVEVEVP----EPPPK 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 289 PQSDVMAGIDVNPDRIAV--------------------------------SLCTKQGNFKDSKIFYLHNLNTFSTNKRGT 336
Cdd:NF040570  189 EVTGKVVGIDLGLKNFATlsdggekienprflrkkekrlrrlqrklsrklQRKGKGSSNRKKARKKVARLHRKIANQRKD 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1264956978 337 IIGQIVQQIKTWLLENNVGGIVLEDLQFQQSHdTDKYSNRNFHQFTYKKMLNNLIRMALRNGLSVKTVNPAYTSVIGKLK 416
Cdd:NF040570  269 FLHKLSKRLVKEADANNVVVEDLEVKGMVKNK-KKKKLAKSIHDWAFGQLRRMLEYKAEWYGIKVVKVDPAYTSSQCCSC 347


                  ....
gi 1264956978 417 YSKK 420
Cdd:NF040570  348 GGHR 351
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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