NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1265152521|gb|PGQ78616|]
View 

N-acetyltransferase [Priestia megaterium]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11447364)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
SCOP:  3000403

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
3-164 5.93e-11

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 57.70  E-value: 5.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521   3 IRLLVKEDADAYFELR-----LRALKDHPESfilsyEEEYEKEIADIRNYFpsSQSEFVVGAFIEK---QLVGIVGFQQQ 74
Cdd:COG1670    10 LRPLRPEDAEALAELLndpevARYLPGPPYS-----LEEARAWLERLLADW--ADGGALPFAIEDKedgELIGVVGLYDI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521  75 KPlkVQHKGDIwGMYVAPEARGKGLGKKLLKTAVEQAFSKTNVLQIYLAVAAKNEGAKVLYKSLGFTSYAYEKRALQVDG 154
Cdd:COG1670    83 DR--ANRSAEI-GYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVIDG 159
                         170
                  ....*....|
gi 1265152521 155 EFIDEEHMVL 164
Cdd:COG1670   160 RYRDHVLYSL 169
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
3-164 5.93e-11

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 57.70  E-value: 5.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521   3 IRLLVKEDADAYFELR-----LRALKDHPESfilsyEEEYEKEIADIRNYFpsSQSEFVVGAFIEK---QLVGIVGFQQQ 74
Cdd:COG1670    10 LRPLRPEDAEALAELLndpevARYLPGPPYS-----LEEARAWLERLLADW--ADGGALPFAIEDKedgELIGVVGLYDI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521  75 KPlkVQHKGDIwGMYVAPEARGKGLGKKLLKTAVEQAFSKTNVLQIYLAVAAKNEGAKVLYKSLGFTSYAYEKRALQVDG 154
Cdd:COG1670    83 DR--ANRSAEI-GYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVIDG 159
                         170
                  ....*....|
gi 1265152521 155 EFIDEEHMVL 164
Cdd:COG1670   160 RYRDHVLYSL 169
Acetyltransf_4 pfam13420
Acetyltransferase (GNAT) domain;
3-159 1.91e-09

Acetyltransferase (GNAT) domain;


Pssm-ID: 433192 [Multi-domain]  Cd Length: 153  Bit Score: 53.52  E-value: 1.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521   3 IRLLVKEDADAYfeLRLRALKDHPESFILSYE----EEYEKEIADIrnyfpSSQSEFVVGAFIEKQLVGIVGFQQQKPLK 78
Cdd:pfam13420   1 IRALTQNDLKEI--RRWYAEDRVNPAFTQEYAhssiEEFETFLAAY-----LSPGEIVFGVAESDRLIGYATLRQFDYVK 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521  79 vQHKGdIWGMYVApeARGKGLGKKLLKTAVEQ-AFSKTNVLQIYLAVAAKNEGAKVLYKSLGFTSYAYEKRALQVDGEFI 157
Cdd:pfam13420  74 -THKA-ELSFYVV--KNNDEGINRELINAIIQyARKNQNIENLEACIASNNINAIVFLKAIGFEWLGIERNAIKKNGRWI 149

                  ..
gi 1265152521 158 DE 159
Cdd:pfam13420 150 DM 151
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
3-164 5.93e-11

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 57.70  E-value: 5.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521   3 IRLLVKEDADAYFELR-----LRALKDHPESfilsyEEEYEKEIADIRNYFpsSQSEFVVGAFIEK---QLVGIVGFQQQ 74
Cdd:COG1670    10 LRPLRPEDAEALAELLndpevARYLPGPPYS-----LEEARAWLERLLADW--ADGGALPFAIEDKedgELIGVVGLYDI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521  75 KPlkVQHKGDIwGMYVAPEARGKGLGKKLLKTAVEQAFSKTNVLQIYLAVAAKNEGAKVLYKSLGFTSYAYEKRALQVDG 154
Cdd:COG1670    83 DR--ANRSAEI-GYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVIDG 159
                         170
                  ....*....|
gi 1265152521 155 EFIDEEHMVL 164
Cdd:COG1670   160 RYRDHVLYSL 169
Acetyltransf_4 pfam13420
Acetyltransferase (GNAT) domain;
3-159 1.91e-09

Acetyltransferase (GNAT) domain;


Pssm-ID: 433192 [Multi-domain]  Cd Length: 153  Bit Score: 53.52  E-value: 1.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521   3 IRLLVKEDADAYfeLRLRALKDHPESFILSYE----EEYEKEIADIrnyfpSSQSEFVVGAFIEKQLVGIVGFQQQKPLK 78
Cdd:pfam13420   1 IRALTQNDLKEI--RRWYAEDRVNPAFTQEYAhssiEEFETFLAAY-----LSPGEIVFGVAESDRLIGYATLRQFDYVK 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521  79 vQHKGdIWGMYVApeARGKGLGKKLLKTAVEQ-AFSKTNVLQIYLAVAAKNEGAKVLYKSLGFTSYAYEKRALQVDGEFI 157
Cdd:pfam13420  74 -THKA-ELSFYVV--KNNDEGINRELINAIIQyARKNQNIENLEACIASNNINAIVFLKAIGFEWLGIERNAIKKNGRWI 149

                  ..
gi 1265152521 158 DE 159
Cdd:pfam13420 150 DM 151
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-162 1.57e-07

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 48.45  E-value: 1.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521   1 MNIRLLVKEDADAYFELRLRALKDHPESFilSYEEEYEKEIADIRNYFPSSQSEFVVgAFIEKQLVGIVGFQQQKPLKVQ 80
Cdd:COG1247     2 MTIRPATPEDAPAIAAIYNEAIAEGTATF--ETEPPSEEEREAWFAAILAPGRPVLV-AEEDGEVVGFASLGPFRPRPAY 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521  81 HKGDIWGMYVAPEARgkglgkkllkTAVEQAFSKTNVLQIYLAVAAKNEGAKVLYKSLGFTSYAYEKRALQVDGEFIDEE 160
Cdd:COG1247    79 RGTAEESIYVDPDARgrgig-rallEALIERARARGYRRLVAVVLADNEASIALYEKLGFEEVGTLPEVGFKFGRWLDLV 157

                  ..
gi 1265152521 161 HM 162
Cdd:COG1247   158 LM 159
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
27-140 6.80e-05

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 40.19  E-value: 6.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521  27 ESFILSYEEEYEKEIADIRNYFPSSQSEFVVGAFIEKQLVGIVGFQQQKPlkVQHKGDIWGMYVAPEARGKGLGKKLLKT 106
Cdd:pfam00583   6 ELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDD--EPPVGEIEGLAVAPEYRGKGIGTALLQA 83
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1265152521 107 AVEQAFSKtNVLQIYLAVAAKNEGAKVLYKSLGF 140
Cdd:pfam00583  84 LLEWARER-GCERIFLEVAADNLAAIALYEKLGF 116
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
3-95 2.31e-03

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 36.60  E-value: 2.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521   3 IRLLVKEDADAYFELRLRALKDHPESFIlsyeeeyekeIADIRNyfpSSQSEFVVGAFIEKQLVGIVGFQQQKPLKVQHK 82
Cdd:COG3153     1 IRPATPEDAEAIAALLRAAFGPGREAEL----------VDRLRE---DPAAGLSLVAEDDGEIVGHVALSPVDIDGEGPA 67
                          90
                  ....*....|...
gi 1265152521  83 GDIWGMYVAPEAR 95
Cdd:COG3153    68 LLLGPLAVDPEYR 80
Eis COG4552
Predicted acetyltransferase [General function prediction only];
1-95 2.33e-03

Predicted acetyltransferase [General function prediction only];


Pssm-ID: 443616 [Multi-domain]  Cd Length: 393  Bit Score: 37.57  E-value: 2.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521   1 MNIRLLVKEDADAYFELRLRAlkdhpesFILSYEEEyekeiaDIRNYFPSSQSEFVVGAFIEKQLVGIVG---FQQQ--- 74
Cdd:COG4552     1 MEIRPLTEDDLDAFARLLAYA-------FGPEPDDE------ELEAYRPLLEPGRVLGVFDDGELVGTLAlypFTLNvgg 67
                          90       100
                  ....*....|....*....|.
gi 1265152521  75 KPLKVqhkGDIWGMYVAPEAR 95
Cdd:COG4552    68 ARVPM---AGITGVAVAPEHR 85
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
42-141 7.68e-03

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 35.03  E-value: 7.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1265152521  42 ADIRNYFPSSQSEFVVGAFIEKQLVGIVGFQQqkplKVQHKGDIWGMYVAPEARGKGLGKKLLKTAVEQAFSKtNVLQIY 121
Cdd:COG0454    22 AELKAMEGSLAGAEFIAVDDKGEPIGFAGLRR----LDDKVLELKRLYVLPEYRGKGIGKALLEALLEWARER-GCTALE 96
                          90       100
                  ....*....|....*....|
gi 1265152521 122 LAVAAKNEGAKVLYKSLGFT 141
Cdd:COG0454    97 LDTLDGNPAAIRFYERLGFK 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH