|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-429 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 791.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 1 MSSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 81 EELKYLHDRGVST-DNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEK 159
Cdd:PRK01117 81 KEIDELEARGVDVrERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 160 LERNLVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 240 SNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARR 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 320 VSGLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVER 399
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKR 400
|
410 420 430
....*....|....*....|....*....|
gi 1266634982 400 VSELTGIQLSMFSVGPDRNQTNIVRNVYEA 429
Cdd:PRK01117 401 IEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-425 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 763.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 3 SVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 83 LKYLHDRGVST-DNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLE 161
Cdd:COG0104 81 IDGLEARGVDVrSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 162 RNLVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 242 PIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVS 321
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 322 GLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVERVS 401
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIE 400
|
410 420
....*....|....*....|....
gi 1266634982 402 ELTGIQLSMFSVGPDRNQTnIVRN 425
Cdd:COG0104 401 ELLGVPISIVSVGPDREQT-IVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-420 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 728.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 5 VVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEELK 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 85 YLHDRGVS-TDNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLERN 163
Cdd:pfam00709 81 ELEERGIDvPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 164 LVEKNRLFEKMYDtEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSNPI 243
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 244 AGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGL 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 324 TDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVERVSEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*..
gi 1266634982 404 TGIQLSMFSVGPDRNQT 420
Cdd:pfam00709 400 LGVPIKIISVGPDREQT 416
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-420 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 690.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 3 SVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 83 LKYLHDRGV-STDNLRVSNRAHVILPYHLKQDELEEASKgdnkIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLE 161
Cdd:smart00788 81 IEELEAKGVdVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 162 RNLVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 242 PIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVS 321
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 322 GLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVERVS 401
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIE 396
|
410
....*....|....*....
gi 1266634982 402 ELTGIQLSMFSVGPDRNQT 420
Cdd:smart00788 397 ELVGVPVSIISTGPDREQT 415
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-427 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 617.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 5 VVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEELK 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 85 YLHDRGVST-DNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLERN 163
Cdd:TIGR00184 81 YLEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 164 LVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSNPI 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 244 AGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGL 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 324 TDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVERVSEL 403
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|....
gi 1266634982 404 TGIQLSMFSVGPDRNQTNIVRNVY 427
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRKEL 424
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-420 |
7.61e-174 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 488.55 E-value: 7.61e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 2 SSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLE 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 82 ELKYLHDRGV-STDNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADlldreafkekl 160
Cdd:cd03108 81 EIEELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 161 ernlveknrlfekmydtegfsveeifeeyfeygqqiaQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSS 240
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 241 NPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRV 320
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 321 SGLTDLSLNSIDVltgiptlkicvaykyngevidevpanlnilakcepvyeelpgwteditgvksldelpeNARKYVERV 400
Cdd:cd03108 273 NGLTELALTKLDV----------------------------------------------------------NAQKYIERI 294
|
410 420
....*....|....*....|
gi 1266634982 401 SELTGIQLSMFSVGPDRNQT 420
Cdd:cd03108 295 EELLGVPITYISVGPDREQT 314
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-322 |
7.22e-37 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 136.35 E-value: 7.22e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 5 VVVGTQWGDEGKGKITDFLSEHAEVVARYQ-GGNNAGHTIV-FGGVKYKLHLIPSGIFY-KEKICVIGNGLVVDPKALLE 81
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIdDEGRKFVHRMLPNGIVSpPLKQVLIGPGSEIDLEVLRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 82 ELKYLHDRGVST-DNLRVSNRAHVILpyhlKQDELEEASKGDNKIGTTKKGIGPAYMDK----AARIGIRMADLLDREAF 156
Cdd:NF038379 83 EIEELEDAGHDVgKRLLIHEQATVIE----LHKHVEEEAGPMTKIGSTKKGIGAARAAKirrnPSTLGDAEGDFGEGAVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 157 KEKLErnlveknrlfekmydtegfsveeifeeyfeygqqIAQYVCDTSVVLnDALDNNHRVLFEGAQGVMLDIDHGTYPF 236
Cdd:NF038379 159 DQPWE----------------------------------IAERVVDNALYD-FALQAAERIQIEGTQGYSLGLHAGFYPY 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 237 VTSSN--PIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGD-----GPFPTELH-DEIGhqireVGREYGTTTGRPRRVGW 308
Cdd:NF038379 204 CTSRDctPADFLADAGIPLPNVDAFKVVGTARTYPIRVAGwsgnsYPDQGETTwEELG-----LPEELTTVTKKVRRVGT 278
|
330
....*....|....
gi 1266634982 309 FDSVVVRHARRVSG 322
Cdd:NF038379 279 FSAEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-429 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 791.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 1 MSSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 81 EELKYLHDRGVST-DNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEK 159
Cdd:PRK01117 81 KEIDELEARGVDVrERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 160 LERNLVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 240 SNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARR 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 320 VSGLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVER 399
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKR 400
|
410 420 430
....*....|....*....|....*....|
gi 1266634982 400 VSELTGIQLSMFSVGPDRNQTNIVRNVYEA 429
Cdd:PRK01117 401 IEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-425 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 763.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 3 SVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 83 LKYLHDRGVST-DNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLE 161
Cdd:COG0104 81 IDGLEARGVDVrSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 162 RNLVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 242 PIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVS 321
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 322 GLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVERVS 401
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIE 400
|
410 420
....*....|....*....|....
gi 1266634982 402 ELTGIQLSMFSVGPDRNQTnIVRN 425
Cdd:COG0104 401 ELLGVPISIVSVGPDREQT-IVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-420 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 728.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 5 VVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEELK 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 85 YLHDRGVS-TDNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLERN 163
Cdd:pfam00709 81 ELEERGIDvPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 164 LVEKNRLFEKMYDtEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSNPI 243
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 244 AGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGL 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 324 TDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVERVSEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*..
gi 1266634982 404 TGIQLSMFSVGPDRNQT 420
Cdd:pfam00709 400 LGVPIKIISVGPDREQT 416
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-420 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 690.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 3 SVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 83 LKYLHDRGV-STDNLRVSNRAHVILPYHLKQDELEEASKgdnkIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLE 161
Cdd:smart00788 81 IEELEAKGVdVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 162 RNLVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 242 PIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVS 321
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 322 GLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVERVS 401
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIE 396
|
410
....*....|....*....
gi 1266634982 402 ELTGIQLSMFSVGPDRNQT 420
Cdd:smart00788 397 ELVGVPVSIISTGPDREQT 415
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-427 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 617.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 5 VVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEELK 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 85 YLHDRGVST-DNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLERN 163
Cdd:TIGR00184 81 YLEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 164 LVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSNPI 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 244 AGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGL 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 324 TDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVERVSEL 403
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|....
gi 1266634982 404 TGIQLSMFSVGPDRNQTNIVRNVY 427
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRKEL 424
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
1-424 |
7.88e-177 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 500.71 E-value: 7.88e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 1 MSSVVVV-GTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFG-GVKYKLHLIPSGIFYKEKICVIGNGLVVDPKA 78
Cdd:PLN02513 1 LSQVSAVlGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNDeGKKFALHLVPSGILNEKTTCVIGNGVVVHLPG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 79 LLEELKYLHDRGVSTDN-LRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFK 157
Cdd:PLN02513 81 LFEEIDGLESNGVSCEGrLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 158 EKLERNLVEKNRLFEKmYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFV 237
Cdd:PLN02513 161 EKLRELLADAAARFEG-FEYDASMVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 238 TSSNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHA 317
Cdd:PLN02513 240 TSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 318 RRVSGLTDLSLNSIDVLTGIPTLKICVAYKY-NGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKY 396
Cdd:PLN02513 320 CQINGFTSLNLTKLDVLSGLPEIKIGVAYKTpDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAY 399
|
410 420
....*....|....*....|....*...
gi 1266634982 397 VERVSELTGIQLSMFSVGPDRNQTnIVR 424
Cdd:PLN02513 400 VERIEELVGVPVHYIGVGPGRDAL-IVK 426
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-420 |
7.61e-174 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 488.55 E-value: 7.61e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 2 SSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLE 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 82 ELKYLHDRGV-STDNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADlldreafkekl 160
Cdd:cd03108 81 EIEELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 161 ernlveknrlfekmydtegfsveeifeeyfeygqqiaQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSS 240
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 241 NPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRV 320
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 321 SGLTDLSLNSIDVltgiptlkicvaykyngevidevpanlnilakcepvyeelpgwteditgvksldelpeNARKYVERV 400
Cdd:cd03108 273 NGLTELALTKLDV----------------------------------------------------------NAQKYIERI 294
|
410 420
....*....|....*....|
gi 1266634982 401 SELTGIQLSMFSVGPDRNQT 420
Cdd:cd03108 295 EELLGVPITYISVGPDREQT 314
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
4-424 |
2.67e-170 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 484.53 E-value: 2.67e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 4 VVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEEL 83
Cdd:PTZ00350 15 VVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLLEEI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 84 KYLHDRGVS-TDNLRVSNRAHVILPYHLKQDELEEASKGDN--KIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKL 160
Cdd:PTZ00350 95 EQLTKKGINlLGRLYISDRAHLVFDLHQAIDGIQESEKGKGgtQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFEKKY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 161 eRNLVEKnrlFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSS 240
Cdd:PTZ00350 175 -RKLVEK---LQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVTSS 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 241 NPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRV 320
Cdd:PTZ00350 251 NTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQMI 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 321 SGLTDLSLNSIDVLTGIPTLKICVAYKYNGEV--IDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVE 398
Cdd:PTZ00350 331 NGFDSINLTKLDVLSGLKEIKICVNYKNKGTGleIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQKYVL 410
|
410 420
....*....|....*....|....*.
gi 1266634982 399 RVSELTGIQLSMFSVGPDRNQTnIVR 424
Cdd:PTZ00350 411 FIEELLGVPIVWIGVGPNRENM-IVK 435
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
5-420 |
1.28e-154 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 444.24 E-value: 1.28e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 5 VVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKIcVIGNGLVVDPKALLEELK 84
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARV-LIGPGVVLNPEVLAEEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 85 YLHDRG--VSTDNLRVSNRAHVILPYHLKQDELEEASKgDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLER 162
Cdd:PRK13786 83 MLEKHGvkVDAEKLGIDAKTSIIMPYHIELDGLRESAR-TEKIGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 163 NLVEKNRLFEKMY-DTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:PRK13786 162 LAPQKEKEIKELGgDPSIVRDEALIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFVTSSS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 242 PIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVS 321
Cdd:PRK13786 242 TIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKAIYLN 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 322 GLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPGWTEDITGVKSLDELPENARKYVERVS 401
Cdd:PRK13786 322 GYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYVERLE 401
|
410
....*....|....*....
gi 1266634982 402 ELTGIQLSMFSVGPDRNQT 420
Cdd:PRK13786 402 ELMGVPIKYISVGPGREQT 420
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
1-420 |
1.75e-142 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 413.19 E-value: 1.75e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 1 MSSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALL 80
Cdd:PRK13787 1 MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 81 EELKYLHDRGVST-DNLRVSNRAHVILPYHLKQDELEEA-SKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDReAFKE 158
Cdd:PRK13787 81 EECDRLQKEGFPVkDKLLLSDACHLLFPYHSQIDSARETtSSQEHKIGTTKKGIGICYADKMMRTGLRVGDLLDK-SYKR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 159 KLERNLVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVT 238
Cdd:PRK13787 160 RLKHLVDEKNRELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 239 SSNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHAR 318
Cdd:PRK13787 240 SSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHSV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 319 RVSGLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLniLAKCEPVYEELPGWTEDITGVKSLDELPENARKYVE 398
Cdd:PRK13787 320 RINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPSQG--LEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYIS 397
|
410 420
....*....|....*....|..
gi 1266634982 399 RVSELTGIQLSMFSVGPDRNQT 420
Cdd:PRK13787 398 ALEKWIGVKINLVSTGPDRKDT 419
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
3-427 |
3.10e-139 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 406.07 E-value: 3.10e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 3 SVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFyKEKICVIGNGLVVDPKALLEE 82
Cdd:PRK13785 2 TVTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAV-RGKIGVLGNGCVVNPETLFDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 83 LKYLHDRGVSTDnLRVSNRAHVILPYHLKQDELEEASKGDN--KIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKL 160
Cdd:PRK13785 81 IDALRERGLDPD-VRVAERAHVILPYHRVLDGIEEEAKSDSdlEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 161 ERNLVEKNRLFEKMYD------TEGFSVEEIFEEYFEYGQQIAQ--YVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHG 232
Cdd:PRK13785 160 EYVVPQKRALAEDVYGldasetPEAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDGDNVMLEGAQGTSIDIDHG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 233 TYPFVTSSNPIAGGVTVGTGVGPAKVTR--VVGVCKAYTSRVGDGPFPTEL---------------HDEIGHQIREVGRE 295
Cdd:PRK13785 240 NYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTELggvegdtpdeggrpdEEELATYIREEGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 296 YGTTTGRPRRVGWFDSVVVRHARRVSGLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNILAKCEPVYEELPG 375
Cdd:PRK13785 320 YGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNFRSFDG 399
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1266634982 376 WTE-DITGVKS--LDELPENARKYVERVSELTGIQLSMFSVGPDRNQTNIVRNVY 427
Cdd:PRK13785 400 WPEvDWAAVAEegYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVLENPF 454
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
1-420 |
3.85e-139 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 403.80 E-value: 3.85e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 1 MSSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALL 80
Cdd:PRK13788 1 MPGIAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 81 EELKYLHDRGVSTDnLRVSNRAHVILPYHLKQDEleeaskGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKL 160
Cdd:PRK13788 81 EERENLRAGGLNPK-LLISERAHLVLPHHKYVDG------RKNFVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRERV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 161 ERNLVEK-NRLFEKMYDTegfsVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTS 239
Cdd:PRK13788 154 ERLLEAKpNSTREAGWDT----VEKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 240 SNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVG----REYGTTTGRPRRVGWFDSVVVR 315
Cdd:PRK13788 230 SHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 316 HARRVSGLTDLSLNSIDVLTGIPTLKICVAYKYNGevidevpanlnilakcEPVYEELPGWTeDITGVKSLDELPENARK 395
Cdd:PRK13788 310 YACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDG----------------QPVYKELPGWG-DLDGVKSREALPKEAQA 372
|
410 420
....*....|....*....|....*
gi 1266634982 396 YVERVSELTGIQLSMFSVGPDRNQT 420
Cdd:PRK13788 373 YLELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
5-415 |
6.77e-135 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 393.31 E-value: 6.77e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 5 VVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEELK 84
Cdd:PRK13783 4 VIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVEELE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 85 YLHDR-GVSTDNLRVSNRAHVILPYHLKQDELEEASKGdNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLERN 163
Cdd:PRK13783 84 ELKEKfPDYSGRIFISELAHVVLPVHKELDEIIESVRK-NAIGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFLEKI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 164 LVEKNRLFEKMYDTEgfsveEIFEEYFEYGQQIAQYVCDtSVVLNDALDNNhRVLFEGAQGVMLDIDHGTYPFVTSSNPI 243
Cdd:PRK13783 163 LSLYKKLYGIEFDVE-----KMMEDLLTFYEKIKDLVVS-PVEIKRILEEK-SVLFEGTQGVLLDLDVGTYPYVTSSNCS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 244 AGGVTVGTGVgPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGL 323
Cdd:PRK13783 236 TTGVSAGMGF-PVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEVSGV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 324 TDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEvPANLNILAKCEPVYEELPGWteditgvKSLDElpENARKYVERVSEL 403
Cdd:PRK13783 315 DSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGW-------KSLED--KNFLKFVDFIERE 384
|
410
....*....|..
gi 1266634982 404 TGIQLSMFSVGP 415
Cdd:PRK13783 385 TGRKIAYISTGP 396
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
1-419 |
9.72e-116 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 345.08 E-value: 9.72e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 1 MSSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALL 80
Cdd:PRK13784 1 MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 81 EELKYLHDRGV--STDNLRVSNRAHVILPYHLKQDELEEASKGDnKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKE 158
Cdd:PRK13784 81 EEITRLQAKGIaiSAENLFVSESCTIITSYHKLLDAVRESNTSE-KIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 159 KLERNLVEKNRLFEKMYDTEGFSVEEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVT 238
Cdd:PRK13784 160 RLAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 239 SSNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHAR 318
Cdd:PRK13784 240 SSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 319 RVSGLTDLSLNSIDVLTGIPTLKICVAYKYNGEVIDEVPANLNiLAKCEPVYEELPGWTEDITGVKslDELPENARKYVE 398
Cdd:PRK13784 320 KCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEIYCAYPGID-LYKVEPILVEMEPFSIDETVTK--DNMPAALKTYLK 396
|
410 420
....*....|....*....|.
gi 1266634982 399 RVSELTGIQLSMFSVGPDRNQ 419
Cdd:PRK13784 397 TIENHVGIPISSLAYGPSREQ 417
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
1-420 |
5.46e-75 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 237.47 E-value: 5.46e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 1 MSSVVVVGTQWGDEGKGKITDFLS--EHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKA 78
Cdd:PRK04293 1 MTCTIVVGGFFGDEGKGKIIAYLAlkDKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 79 LLEELKYLHdrgvSTDNLRVSNRAHVILPYHLKQDeleeasKGD----NKIGTTKKGIGPAYMDKAARIGirmadlldre 154
Cdd:PRK04293 81 LLKEVEELN----VGGRVFVDYRCGIIEEKHVEED------RSDehlsKKIGSTGTGCGPANADRVLRRL---------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 155 afkeKLERNLVEknrlfekmydtegfsveeifeeyfeygqqIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTY 234
Cdd:PRK04293 141 ----KLAKDVEE-----------------------------LEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTY 187
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 235 PFVTSSNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVgrEYGTTTGRPRRVGWFDSVVV 314
Cdd:PRK04293 188 PYVTSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELA 265
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 315 RHARRVSGLTDLSLNSIDVLtgiptlkicvaYKyngevidevpanlnilakcepvyeelpgwteDITGVKSLDELPENAR 394
Cdd:PRK04293 266 RRAARINGATQIAITKLDKL-----------DK-------------------------------EAYGVTEYDKLPPEAK 303
|
410 420
....*....|....*....|....*.
gi 1266634982 395 KYVERVSELTGIQLSMFSVGPDRNQT 420
Cdd:PRK04293 304 KFIEEIEEELGVPVTLISTGPELEDT 329
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-322 |
7.22e-37 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 136.35 E-value: 7.22e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 5 VVVGTQWGDEGKGKITDFLSEHAEVVARYQ-GGNNAGHTIV-FGGVKYKLHLIPSGIFY-KEKICVIGNGLVVDPKALLE 81
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIdDEGRKFVHRMLPNGIVSpPLKQVLIGPGSEIDLEVLRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 82 ELKYLHDRGVST-DNLRVSNRAHVILpyhlKQDELEEASKGDNKIGTTKKGIGPAYMDK----AARIGIRMADLLDREAF 156
Cdd:NF038379 83 EIEELEDAGHDVgKRLLIHEQATVIE----LHKHVEEEAGPMTKIGSTKKGIGAARAAKirrnPSTLGDAEGDFGEGAVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 157 KEKLErnlveknrlfekmydtegfsveeifeeyfeygqqIAQYVCDTSVVLnDALDNNHRVLFEGAQGVMLDIDHGTYPF 236
Cdd:NF038379 159 DQPWE----------------------------------IAERVVDNALYD-FALQAAERIQIEGTQGYSLGLHAGFYPY 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 237 VTSSN--PIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGD-----GPFPTELH-DEIGhqireVGREYGTTTGRPRRVGW 308
Cdd:NF038379 204 CTSRDctPADFLADAGIPLPNVDAFKVVGTARTYPIRVAGwsgnsYPDQGETTwEELG-----LPEELTTVTKKVRRVGT 278
|
330
....*....|....
gi 1266634982 309 FDSVVVRHARRVSG 322
Cdd:NF038379 279 FSAEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
4-164 |
1.28e-16 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 82.02 E-value: 1.28e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 4 VVVVGTQWGDEGKGKITDFLSEH--AEVVARYQGGNNAGHTIV-FGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALL 80
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYdKAGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266634982 81 E-ELKYLHDRGVS-TDNLRVSNRAhVILPYHLKQDELEEASKgdnkiGTTKKGIGPAYMDKAARIGIRMADLL-DREAFK 157
Cdd:PTZ00351 252 EkEIIQLIDAGIDyRDRLFIGNVC-IVTPYHKLLDLLGSAAN-----SSTLKGMAPVHGSKVMKRGIRLDHIFnDDETLR 325
|
....*..
gi 1266634982 158 EKLERNL 164
Cdd:PTZ00351 326 KRLEKDM 332
|
|
| |
