|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
5-846 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1580.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 5 AKETLPVSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTA 84
Cdd:PRK05560 2 GDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 85 VYDTIVRMAQNFSLRYPLVDGQGNFGSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIP 164
Cdd:PRK05560 82 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 165 NLLINGSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRA 244
Cdd:PRK05560 162 NLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 245 KCHFEEIdksNGRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEMPEVILNNLYKH 324
Cdd:PRK05560 242 KAEIEEI---KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKH 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 325 TQMQDTFGMNMVALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAPTP 404
Cdd:PRK05560 319 TQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTP 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 405 ADAKAGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVM 484
Cdd:PRK05560 399 AEAKEGLMER-----------------------------------FGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELL 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 485 DRITDLLDILDKQERVTLIITEELTAIRNQFGDKRRSEIVENAAGFNLEDLITPEDVMVTLSNTGYIKSQPIDEYRTQKR 564
Cdd:PRK05560 444 ALIADLKDILASPERLLEIIKEELLEIKEKFGDPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRR 523
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 565 GGRGKQAAATKEEDFIESLFVANSHDYILCFTDRGRMFWLKVYEVPQGGRVSRGKPIVNLLKLDEGEKVTAILPVKEFDD 644
Cdd:PRK05560 524 GGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDD 603
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 645 RHYIFMATANGTVKKTALSEFSRPRSNGIIAVRLDDGDYLIGVAITDSQHDVMLFTDAGKANRFDENDVRPTGRDSRGVR 724
Cdd:PRK05560 604 DKYLFFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVR 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 725 GVRLPVHGKVIALLVAESEEQSVLTATENGYGKRTPVAEYTRHNRGGQGMIAIQTSERNGKVVAATLVEPSDEIMLITTG 804
Cdd:PRK05560 684 GIKLREGDEVVSMDVVREDSQEILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDS 763
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 1278093639 805 GVLIRTRVSEIREMGRTTQGVTLINLDKGERLSGLQRVAESE 846
Cdd:PRK05560 764 GKLIRTRVSEISITGRNTQGVRLIRLDEGDKVVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
2-839 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1454.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 2 EQFAKETLPVSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHG 81
Cdd:COG0188 4 PPPAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 82 DTAVYDTIVRMAQNFSLRYPLVDGQGNFGSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPA 161
Cdd:COG0188 84 DSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 162 KIPNLLINGSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVV 241
Cdd:COG0188 164 RFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRGSIR 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 242 MRAKCHFEEIdkSNGRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEMPEVILNNL 321
Cdd:COG0188 244 VRAKAEIEEL--KRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 322 YKHTQMQDTFGMNMVALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAA 401
Cdd:COG0188 322 YKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRAS 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 402 PTPADAKAGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYR 481
Cdd:COG0188 402 KDPDEAKEALMER-----------------------------------FGLSEIQAEAILDMRLRRLTGLEREKIEDEYA 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 482 EVMDRITDLLDILDKQERVTLIITEELTAIRNQFGDKRRSEIVENAAGFNLEDLITPEDVMVTLSNTGYIKSQPIDEYRT 561
Cdd:COG0188 447 ELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRA 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 562 QKRGGRGKQAAATKEEDFIESLFVANSHDYILCFTDRGRMFWLKVYEVPQGGRVSRGKPIVNLLKLDEGEKVTAILPVKE 641
Cdd:COG0188 527 QRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKE 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 642 FDDRHYIFMATANGTVKKTALSEFSRPRSNGIIAVRLDDGDYLIGVAITDSQHDVMLFTDAGKANRFDENDVRPTGRDSR 721
Cdd:COG0188 607 FDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTAR 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 722 GVRGVRLPVHGKVIALLVAEsEEQSVLTATENGYGKRTPVAEYTRHNRGGQGMIAIQTSERNGKVVAATLVEPSDEIMLI 801
Cdd:COG0188 687 GVRGIRLKEGDEVVGMAVVD-EEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLI 765
|
810 820 830
....*....|....*....|....*....|....*...
gi 1278093639 802 TTGGVLIRTRVSEIREMGRTTQGVTLINLDKGERLSGL 839
Cdd:COG0188 766 TSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
9-844 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1254.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 9 LPVSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTAVYDT 88
Cdd:TIGR01063 2 VPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYDT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 89 IVRMAQNFSLRYPLVDGQGNFGSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLI 168
Cdd:TIGR01063 82 LVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLLV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 169 NGSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRAKCHF 248
Cdd:TIGR01063 162 NGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAEI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 249 EEidKSNGRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEMPEVILNNLYKHTQMQ 328
Cdd:TIGR01063 242 EE--DSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 329 DTFGMNMVALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAPTPADAK 408
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 409 AGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMDRIT 488
Cdd:TIGR01063 400 TRLVER-----------------------------------FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIA 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 489 DLLDILDKQERVTLIITEELTAIRNQFGDKRRSEIVENAAG-FNLEDLITPEDVMVTLSNTGYIKSQPIDEYRTQKRGGR 567
Cdd:TIGR01063 445 DLEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYDESEdIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGK 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 568 GKQAAATKEEDFIESLFVANSHDYILCFTDRGRMFWLKVYEVPQGGRVSRGKPIVNLLKLDEGEKVTAILPVKEFDDRHY 647
Cdd:TIGR01063 525 GVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLY 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 648 IFMATANGTVKKTALSEFSRPRSNGIIAVRLDDGDYLIGVAITDSQHDVMLFTDAGKANRFDENDVRPTGRDSRGVRGVR 727
Cdd:TIGR01063 605 LFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIK 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 728 LPVHGKVIALLVAeSEEQSVLTATENGYGKRTPVAEYTRHNRGGQGMIAIQTSERNGKVVAATLVEPSDEIMLITTGGVL 807
Cdd:TIGR01063 685 LKNEDFVVSLLVV-SEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKL 763
|
810 820 830
....*....|....*....|....*....|....*..
gi 1278093639 808 IRTRVSEIREMGRTTQGVTLINLDKGERLSGLQRVAE 844
Cdd:TIGR01063 764 IRTSVQDVSEQGRNTQGVRLIRLDEDDKLVSVSKVAK 800
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
30-511 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 691.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 30 VGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQNFSLRYPLVDGQGNF 109
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 110 GSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLINGSSGIAVGMATNIPPHNLNE 189
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 190 IVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRAKCHFEEIDksnGRQAIIVDELPYQV 269
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE---GRNTIEITELPYQV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 270 NKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEMPEVILNNLYKHTQMQDTFGMNMVAL-LEGQPRLLNL 348
Cdd:cd00187 238 NKAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFdPNGRPKKLNL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 349 KQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAptpADAKAGLIGRVWhstlveemlsra 428
Cdd:cd00187 318 KEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELE------------ 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 429 asgeayrpfglvpEYGlhtdgyhLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMDRITDLLDILDKQERVTLIITEEL 508
Cdd:cd00187 383 -------------KLG-------FSEIQADAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEEL 442
|
...
gi 1278093639 509 TAI 511
Cdd:cd00187 443 DEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
11-501 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 639.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 11 VSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTAVYDTIV 90
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 91 RMAQNFSLRYPLVDGQGNFGSV-DGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLIN 169
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 170 GSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYgvdgvrdgyrtGRGRVVMRAKCHFE 249
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 250 EidksngRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDES-DKSGMRMVVELKRGEMPEVILNNLYKHTQMQ 328
Cdd:smart00434 230 D------DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQ 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 329 DTFGMNMVAL-LEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKAR-DRGHVLEGLAVALANVDEIIALIKAAPTPA- 405
Cdd:smart00434 304 TTFSINMLALfDNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAk 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 406 DAKAGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMD 485
Cdd:smart00434 384 EAKEKLMER-----------------------------------FELSEIQADAILDMRLRRLTKLEVEKLEKELKELEK 428
|
490
....*....|....*.
gi 1278093639 486 RITDLLDILDKQERVT 501
Cdd:smart00434 429 EIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
32-508 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 623.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 32 RALPDVRDGLKPVHRRALFAMHELSNDwNKAYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQNFSLRYPLVDGQGNFGS 111
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFELLNL-DKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 112 V-DGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLINGSSGIAVGMATNIPPHNLNEI 190
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 191 VDACLAVLERPEITIdeLIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRAKCHFEEidksngRQAIIVDELPYQVN 270
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED------RKTIVITELPYGVW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 271 KANLCAKIGELVREKAIEGISEIRDESDKsGMRMVVELKRGEMPEVILNNLYKHTQMQDTFGMNMVALLEGQPRLLNLKQ 350
Cdd:pfam00521 232 TSDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 351 MLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAPTPADAKAGLIGRvwhstlveemlsraas 430
Cdd:pfam00521 311 ILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE---------------- 374
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278093639 431 geayrpfglvpeyglhtdgyhLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMDRITDLLDILDKQERVTLIITEEL 508
Cdd:pfam00521 375 ---------------------LSEIQADYLLDMRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
5-846 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1580.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 5 AKETLPVSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTA 84
Cdd:PRK05560 2 GDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 85 VYDTIVRMAQNFSLRYPLVDGQGNFGSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIP 164
Cdd:PRK05560 82 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 165 NLLINGSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRA 244
Cdd:PRK05560 162 NLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 245 KCHFEEIdksNGRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEMPEVILNNLYKH 324
Cdd:PRK05560 242 KAEIEEI---KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKH 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 325 TQMQDTFGMNMVALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAPTP 404
Cdd:PRK05560 319 TQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTP 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 405 ADAKAGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVM 484
Cdd:PRK05560 399 AEAKEGLMER-----------------------------------FGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELL 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 485 DRITDLLDILDKQERVTLIITEELTAIRNQFGDKRRSEIVENAAGFNLEDLITPEDVMVTLSNTGYIKSQPIDEYRTQKR 564
Cdd:PRK05560 444 ALIADLKDILASPERLLEIIKEELLEIKEKFGDPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRR 523
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 565 GGRGKQAAATKEEDFIESLFVANSHDYILCFTDRGRMFWLKVYEVPQGGRVSRGKPIVNLLKLDEGEKVTAILPVKEFDD 644
Cdd:PRK05560 524 GGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDD 603
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 645 RHYIFMATANGTVKKTALSEFSRPRSNGIIAVRLDDGDYLIGVAITDSQHDVMLFTDAGKANRFDENDVRPTGRDSRGVR 724
Cdd:PRK05560 604 DKYLFFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVR 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 725 GVRLPVHGKVIALLVAESEEQSVLTATENGYGKRTPVAEYTRHNRGGQGMIAIQTSERNGKVVAATLVEPSDEIMLITTG 804
Cdd:PRK05560 684 GIKLREGDEVVSMDVVREDSQEILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDS 763
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 1278093639 805 GVLIRTRVSEIREMGRTTQGVTLINLDKGERLSGLQRVAESE 846
Cdd:PRK05560 764 GKLIRTRVSEISITGRNTQGVRLIRLDEGDKVVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
2-839 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1454.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 2 EQFAKETLPVSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHG 81
Cdd:COG0188 4 PPPAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 82 DTAVYDTIVRMAQNFSLRYPLVDGQGNFGSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPA 161
Cdd:COG0188 84 DSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 162 KIPNLLINGSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVV 241
Cdd:COG0188 164 RFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRGSIR 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 242 MRAKCHFEEIdkSNGRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEMPEVILNNL 321
Cdd:COG0188 244 VRAKAEIEEL--KRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 322 YKHTQMQDTFGMNMVALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAA 401
Cdd:COG0188 322 YKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRAS 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 402 PTPADAKAGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYR 481
Cdd:COG0188 402 KDPDEAKEALMER-----------------------------------FGLSEIQAEAILDMRLRRLTGLEREKIEDEYA 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 482 EVMDRITDLLDILDKQERVTLIITEELTAIRNQFGDKRRSEIVENAAGFNLEDLITPEDVMVTLSNTGYIKSQPIDEYRT 561
Cdd:COG0188 447 ELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRA 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 562 QKRGGRGKQAAATKEEDFIESLFVANSHDYILCFTDRGRMFWLKVYEVPQGGRVSRGKPIVNLLKLDEGEKVTAILPVKE 641
Cdd:COG0188 527 QRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKE 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 642 FDDRHYIFMATANGTVKKTALSEFSRPRSNGIIAVRLDDGDYLIGVAITDSQHDVMLFTDAGKANRFDENDVRPTGRDSR 721
Cdd:COG0188 607 FDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTAR 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 722 GVRGVRLPVHGKVIALLVAEsEEQSVLTATENGYGKRTPVAEYTRHNRGGQGMIAIQTSERNGKVVAATLVEPSDEIMLI 801
Cdd:COG0188 687 GVRGIRLKEGDEVVGMAVVD-EEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLI 765
|
810 820 830
....*....|....*....|....*....|....*...
gi 1278093639 802 TTGGVLIRTRVSEIREMGRTTQGVTLINLDKGERLSGL 839
Cdd:COG0188 766 TSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
9-844 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1254.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 9 LPVSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTAVYDT 88
Cdd:TIGR01063 2 VPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYDT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 89 IVRMAQNFSLRYPLVDGQGNFGSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLI 168
Cdd:TIGR01063 82 LVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLLV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 169 NGSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRAKCHF 248
Cdd:TIGR01063 162 NGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAEI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 249 EEidKSNGRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEMPEVILNNLYKHTQMQ 328
Cdd:TIGR01063 242 EE--DSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 329 DTFGMNMVALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAPTPADAK 408
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 409 AGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMDRIT 488
Cdd:TIGR01063 400 TRLVER-----------------------------------FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIA 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 489 DLLDILDKQERVTLIITEELTAIRNQFGDKRRSEIVENAAG-FNLEDLITPEDVMVTLSNTGYIKSQPIDEYRTQKRGGR 567
Cdd:TIGR01063 445 DLEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYDESEdIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGK 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 568 GKQAAATKEEDFIESLFVANSHDYILCFTDRGRMFWLKVYEVPQGGRVSRGKPIVNLLKLDEGEKVTAILPVKEFDDRHY 647
Cdd:TIGR01063 525 GVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLY 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 648 IFMATANGTVKKTALSEFSRPRSNGIIAVRLDDGDYLIGVAITDSQHDVMLFTDAGKANRFDENDVRPTGRDSRGVRGVR 727
Cdd:TIGR01063 605 LFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIK 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 728 LPVHGKVIALLVAeSEEQSVLTATENGYGKRTPVAEYTRHNRGGQGMIAIQTSERNGKVVAATLVEPSDEIMLITTGGVL 807
Cdd:TIGR01063 685 LKNEDFVVSLLVV-SEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKL 763
|
810 820 830
....*....|....*....|....*....|....*..
gi 1278093639 808 IRTRVSEIREMGRTTQGVTLINLDKGERLSGLQRVAE 844
Cdd:TIGR01063 764 IRTSVQDVSEQGRNTQGVRLIRLDEDDKLVSVSKVAK 800
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-773 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 835.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 1 MEQFAKETLPVSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPH 80
Cdd:PRK05561 3 DMSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 81 GDTAVYDTIVRMAQNFSLRYPLVDGQGNFGSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILP 160
Cdd:PRK05561 83 GDSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 161 AKIPNLLINGSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAG-IIYGVDGVRDGYRTGRGR 239
Cdd:PRK05561 163 ARFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGeIITGRDGIRKAYETGRGS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 240 VVMRAKCHFEEIdkSNGRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDESDK-SGMRMVVELKRGEM-PEVI 317
Cdd:PRK05561 243 IRVRARWEIEDL--AGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDReNPVRIVIEPKSNRVdPEAL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 318 LNNLYKHTQMQDTFGMNMVAL-LEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIA 396
Cdd:PRK05561 321 MNHLFATTDLESSYRVNMNAIgLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIR 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 397 LIKAAptpADAKAGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKV 476
Cdd:PRK05561 401 IIRES---DEPKANLMAR-----------------------------------FDLSEIQAEAILELRLRRLAKLEEIEI 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 477 LSEYREVMDRITDLLDILDKQERVTLIITEELTAIRNQFGDKRRSEIVEN--AAGFNLEDLITPEDVMVTLSNTGYIKSq 554
Cdd:PRK05561 443 RKEQDELRKEIAELEAILASERKLRKLIKKELKADAKKFGDPRRTPIEEAeeAIAIDEEALIPDEPVTVVLSKKGWVRR- 521
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 555 pideyrtqkRGGRGKQAAAT--KEEDFIESLFVANSHDYILCFTDRGRMFWLKVYEVPqGGRvSRGKPIVNLLKLDEGEK 632
Cdd:PRK05561 522 ---------AKGHSIDASGLsfKEGDSLLFAFEARTTDKLLLFTSTGRVYSLPVHELP-SAR-GDGEPLTGLVDLAPGEE 590
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 633 VTAILPvkeFDDRHYIFMATANGTVKKTALSEFSRPRSNGIIAVRLDDGDYLIGVAITDSQHDVMLFTDAGKANRFDEND 712
Cdd:PRK05561 591 IVHVLA---FDPDQKLLLASSAGYGFVVTLEDLVARTRAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSE 667
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278093639 713 VRPTGRdSRGVRGVRLPVHGKVIALLVAESEEQSVLTATE-NGYGKRTPVA-EYTRHNRGGQG 773
Cdd:PRK05561 668 LPELGK-GKGVKLINLPKDDDGLVDLRVLNPEDGLVLLTAgKRKLKLKPSElEKYRGKRARRG 729
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
30-511 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 691.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 30 VGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQNFSLRYPLVDGQGNF 109
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 110 GSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLINGSSGIAVGMATNIPPHNLNE 189
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 190 IVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRAKCHFEEIDksnGRQAIIVDELPYQV 269
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE---GRNTIEITELPYQV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 270 NKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEMPEVILNNLYKHTQMQDTFGMNMVAL-LEGQPRLLNL 348
Cdd:cd00187 238 NKAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFdPNGRPKKLNL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 349 KQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAptpADAKAGLIGRVWhstlveemlsra 428
Cdd:cd00187 318 KEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELE------------ 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 429 asgeayrpfglvpEYGlhtdgyhLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMDRITDLLDILDKQERVTLIITEEL 508
Cdd:cd00187 383 -------------KLG-------FSEIQADAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEEL 442
|
...
gi 1278093639 509 TAI 511
Cdd:cd00187 443 DEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
11-501 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 639.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 11 VSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTAVYDTIV 90
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 91 RMAQNFSLRYPLVDGQGNFGSV-DGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLIN 169
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 170 GSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYgvdgvrdgyrtGRGRVVMRAKCHFE 249
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 250 EidksngRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDES-DKSGMRMVVELKRGEMPEVILNNLYKHTQMQ 328
Cdd:smart00434 230 D------DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQ 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 329 DTFGMNMVAL-LEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKAR-DRGHVLEGLAVALANVDEIIALIKAAPTPA- 405
Cdd:smart00434 304 TTFSINMLALfDNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAk 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 406 DAKAGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMD 485
Cdd:smart00434 384 EAKEKLMER-----------------------------------FELSEIQADAILDMRLRRLTKLEVEKLEKELKELEK 428
|
490
....*....|....*.
gi 1278093639 486 RITDLLDILDKQERVT 501
Cdd:smart00434 429 EIEDLEKILASEEWLN 444
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
11-693 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 635.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 11 VSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTAVYDTIV 90
Cdd:PRK13979 16 IPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYDAMV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 91 RMAQNFSLRYPLVDGQGNFGSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLING 170
Cdd:PRK13979 96 ILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLLVNG 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 171 SSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRAKCHFEE 250
Cdd:PRK13979 176 AFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKTKIEK 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 251 IDksNGRQAIIVDELPYQVNKANLCAKIGELVREK----AIEGISEIRDESDKSGMRMVVELKRG---EMPEVILNNLYK 323
Cdd:PRK13979 256 LE--NGRLGIVITEFPYRRNKAKLLQTISEMTADKkhskALENISDIRDESDRNGIRAVIEFKKSadeDVAEKVLKYLYK 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 324 HTQMQDTFGMNMVALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAPT 403
Cdd:PRK13979 334 KTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRSSKS 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 404 PADAkagligrvwHSTLVEEmlsraasgeayrpFGlvpeyglhtdgyhLSDVQAQAILDLRLQRLTGLEQDKVLSEYREV 483
Cdd:PRK13979 414 KKDA---------SENLIEK-------------FG-------------FTDEQAEAILELMLYRLTGLEIVAFEKEYKEL 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 484 MDRITDLLDILDKQERVTLIITEELTAIRNQFGDKRRSEIVE--NAAGFNLEDLITPEDVMVTLSNTGYIKSQPIDEYrt 561
Cdd:PRK13979 459 EKLIKKLTKILSSEKELLKVIKKELKEVKEKYGDERRTSIIEddEKAKIDVEELIVVEDVVITLSNEGFIKRIPLKSY-- 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 562 qKRGGRGKQAAATKEEDFIESLFVANSHDYILCFTDRGRMFWLKVYEVPQGGRVSRGKPIVNLLK-LD-EGEKVTAILPV 639
Cdd:PRK13979 537 -NRSNSNVEDIEYREGDFNKFLIQSNTKDTLLIFTDKGNMYQIKGINIPEFKWKEKGERLDEIIKgIDlESEKIIEAYSI 615
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 1278093639 640 KEFDDRHYIFMATANGTVKKTALSEFSRPRSNgIIAVRLDDGDYLIGVAITDSQ 693
Cdd:PRK13979 616 EDFTPQKDFIFITDSGGIKKTSLDKFVTNYTK-LMALKLKKGEKLIKVKLVDRT 668
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
32-508 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 623.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 32 RALPDVRDGLKPVHRRALFAMHELSNDwNKAYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQNFSLRYPLVDGQGNFGS 111
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFELLNL-DKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 112 V-DGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLINGSSGIAVGMATNIPPHNLNEI 190
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 191 VDACLAVLERPEITIdeLIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRAKCHFEEidksngRQAIIVDELPYQVN 270
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED------RKTIVITELPYGVW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 271 KANLCAKIGELVREKAIEGISEIRDESDKsGMRMVVELKRGEMPEVILNNLYKHTQMQDTFGMNMVALLEGQPRLLNLKQ 350
Cdd:pfam00521 232 TSDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 351 MLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAPTPADAKAGLIGRvwhstlveemlsraas 430
Cdd:pfam00521 311 ILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE---------------- 374
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278093639 431 geayrpfglvpeyglhtdgyhLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMDRITDLLDILDKQERVTLIITEEL 508
Cdd:pfam00521 375 ---------------------LSEIQADYLLDMRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
12-773 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 617.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 12 SLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTAVYDTIVR 91
Cdd:TIGR01061 5 PLEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 92 MAQNFSLRYPLVDGQGNFGSVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLINGS 171
Cdd:TIGR01061 85 MSQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLINGA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 172 SGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAGIIYGVDGVRDGYRTGRGRVVMRAKCHFEEI 251
Cdd:TIGR01061 165 TGIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIEIEVN 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 252 DksNGRQAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEMPEVILNNLYKHTQMQDTF 331
Cdd:TIGR01061 245 K--NGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQINY 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 332 GMNMVALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAPTPADAKAGL 411
Cdd:TIGR01061 323 NFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKENL 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 412 IgrvwhstlveemlsraasgeayrpfglvpeyglhtDGYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMDRITDLL 491
Cdd:TIGR01061 403 I-----------------------------------DNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLE 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 492 DILDKQERVTLIITEELTAIRNQFGDKRRSEIVE--NAAGFNLEDLITPEDVMVTLSNTGYIKsqpideyRTQKRggrgk 569
Cdd:TIGR01061 448 QIIASEKARNKLLKKQLEEYKKQFAQQRRSQIEDfiNQIKINESELIENEDYYVLITKAGYIK-------RTSNR----- 515
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 570 QAAATKEEDF-------IESLFVANSHDYILCFTDRGRMFWLKVYEVPQGGRVSRGKPIVNLLKLDEGEKVTAILPVKEF 642
Cdd:TIGR01061 516 SFASSKYTDFgskdddiLFAQTIANTTDQILIFTSLGNIINIPVHKLADIRWKDLGEHLSNKITFDENETIVFVGTMNEF 595
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 643 D-DRHYIFMATANGTVKKTALSEFS-RPRSNGIIAVRLDDGDYLIGVAITDSQHDVMLFTDAGKANRFDENDVRPTGRDS 720
Cdd:TIGR01061 596 DvDQPILVLASKLGMVKRIELTELNiKRNSKATLCIKLKDKDHLISAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKA 675
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 1278093639 721 RGVRGVRLPVHGKVIALLVAESEEQSVLTaTENGYGKRTPVAEYTRHNRGGQG 773
Cdd:TIGR01061 676 AGVKGMKLKEDDQVKSGVIFEANESLVLL-TQRGSVKRLSISELVVTSRAATG 727
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
11-692 |
2.99e-165 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 498.28 E-value: 2.99e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 11 VSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDVIGKYHPHGDTAVYDTIV 90
Cdd:TIGR01062 4 IDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYEAMV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 91 RMAQNFSLRYPLVDGQGNFGSVDG-DNAAAMRYTEIRMARIAHELLADIDKETVDFGPNYDGSEDEPLILPAKIPNLLIN 169
Cdd:TIGR01062 84 LMAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNILLN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 170 GSSGIAVGMATNIPPHNLNEIVDACLAVLERPEITIDELIAIVPAPDFPTAG-IIYGVDGVRDGYRTGRGRVVMRAKCHF 248
Cdd:TIGR01062 164 GTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAeIIDKAEEIRKIYETGRGSFRMRARWKK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 249 EEIdksngrqAIIVDELPYQVNKANLCAKIGELVREKAIEGISEIRDESDKSG-MRMVVELKRGEM-PEVILNNLYKHTQ 326
Cdd:TIGR01062 244 EDG-------QIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENpIRVVIVPRSNRVdPDIVMEHLFATTD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 327 MQDTFGMNM-VALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGHVLEGLAVALANVDEIIALIKAAPTPa 405
Cdd:TIGR01062 317 LEKSYRLNMnMIGLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREEDEP- 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 406 daKAGLIGRvwhstlveemlsraasgeayrpfglvpeyglhtdgYHLSDVQAQAILDLRLQRLTGLEQDKVLSEYREVMD 485
Cdd:TIGR01062 396 --KTILMER-----------------------------------FKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEK 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 486 RITDLLDILDKQERVTLIITEELTAIRNQFGDKRRSEIVE--NAAGFNLEDLITPEDVMVTLSNTGYIKS---QPIDEYR 560
Cdd:TIGR01062 439 ERAILEKILKSERELNQLVKKEIQADATKYGLARRSSLEEreEAKQVSEIDMIPKEPVTIILSKMGWVRSakgHDIDLST 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 561 TQKRGGRGKQAAATkeedfieslfvANSHDYILCFTDRGRMFWLKVYEVPQGGrvSRGKPIVNLLKLDEGEKVTAILPVK 640
Cdd:TIGR01062 519 LKYKAGDSEKAIIE-----------GKSNQKVVFIDSTGRSYALDPDNLPSAR--GQGEPLTGKLLLPIGATITNILMYS 585
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 641 E------FDDRHYIFMATANGTV--KKTALSEFSRPRSNGIIAVRLDDGDYLIGVAITDS 692
Cdd:TIGR01062 586 PnqlllmASDAGYGFLCNFNDLIarNKAGKALINLPENASVIAPLPVNGDSDMIAAITEA 645
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
17-379 |
6.10e-70 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 243.46 E-value: 6.10e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 17 MRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELsNDWNkaYKKSARIVGDVIgKYHPHGDTAVYDTIVRMAqNF 96
Cdd:PRK09631 8 FKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFEM-HDGK--FHKVANVVGNTM-KYHPHGDASIYEALVNLA-NK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 97 SLrypLVDGQGNFGSV-DGDNAAAMRYTEIRMARIAHELLadIDKETVDFGPNYDGSEDEPLILPAKIPNLLINGSSGIA 175
Cdd:PRK09631 83 DL---FIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVILIQGAEGIA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 176 VGMATNIPPHNLNEIVDACLAVLERPEITIdeliaivpAPDFPTAGIiygVDgvRDGYRTGRGRVVMRAKchFEEIDKsn 255
Cdd:PRK09631 158 VGMATKILPHNFNEILQAVKSELLGESFAL--------YPDFPTGGI---VD--VSEYADGNGKVLVRAK--IETKDE-- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 256 grQAIIVDELPYQVNKANLCAKIGELVREKAIEgISEIrdeSDKSGMRMVVELK--RGEMPEVILNNLYKHTQMQDTFGM 333
Cdd:PRK09631 221 --KTIVIREIPFGTTTESLIASIEKAARKGKIK-ISSI---NDYTAENVEIEIKlpRGVYASEVIEALYAYTDCEVSISV 294
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1278093639 334 NMVALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGH 379
Cdd:PRK09631 295 NLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELERAKLLEKIF 340
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
21-379 |
1.60e-57 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 212.56 E-value: 1.60e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 21 YLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDwnkAYKKSARIVGDVIgKYHPHGDTAVYDTIVRMAQnfslRY 100
Cdd:PRK12758 31 FLDYASYVILERAVPHIEDGLKPVQRRILHSMKEMDDG---RYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ----KD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 101 PLVDGQGNFGSV-DGDNAAAMRYTEIRMARIAHELLadIDKETVDFGPNYDGSEDEPLILPAKIPNLLINGSSGIAVGMA 179
Cdd:PRK12758 103 LLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAVGLS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 180 TNIPPHNLNEIVDACLAVLERPEITIdeliaivpAPDFPTAGIIyGVDGVRDGYRTGRGRVvmRAKchFEEIDKsngrQA 259
Cdd:PRK12758 181 TKILPHNFNELIDASIAYLKGKEFKL--------YPDFPTGGII-DVSNYNDGERGGRVRV--RAK--IEKLDK----KT 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 260 IIVDELPYQVNKANLCAKIgelvrEKAIE-GISEIR--DESDKSGMRMVVELKRGEMPEVILNNLYKHTQMQDTFGMNMV 336
Cdd:PRK12758 244 LVITEIPYGTTTSSLIDSI-----LKANDkGKIKIKkvEDNTAADVEILVHLAPGVSPDKTIDALYAFTDCEVSISPNAC 318
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1278093639 337 ALLEGQPRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRGH 379
Cdd:PRK12758 319 VIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWH 361
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
22-400 |
2.84e-45 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 169.08 E-value: 2.84e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 22 LDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELSNDWNKAYKKSARIVGDV--IGkYHpHGDTAVYDTIVRMAQNFSLR 99
Cdd:PHA02592 17 LEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVadLG-YH-HGETSAQDAGALMANTWNNN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 100 YPLVDGQGNFGSVDGDNAAAMRYTEIRMariaHELLADIDKETvDFGPNYdgsEDEPLILPA----KIPNLLINGSSGIA 175
Cdd:PHA02592 95 IPLLDGQGNFGSRLVQKAAAARYIFARV----HDNFRKIYKDE-DLAPVH---EDPEHIPPAfylpIIPMVLLNGVSGIA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 176 VGMATNIPPHNLNEIVDACLAVLERPEITideliaiVPAPDFPT-AGIIygvdgvrdgYRTGRGRVVMRAKCHFeeidks 254
Cdd:PHA02592 167 TGYATNILPHSPKSVIKAVLAALNGKDIT-------EPKVQFPEfKGEV---------VEIEPGSYEIRGTYEL------ 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 255 NGRQAIIVDELPYQVNKANLCAKIGELVREKAIEGIseirDESDKSGMRMVVELKRGEMPEVILNNLYKHTQMQDTFGMN 334
Cdd:PHA02592 225 NGKTKLHITEIPVKYDRETYVAVLDPLEEKGKIVSY----DDCTEDGFRFKVTLKREENEEATHEKIMKDFGLIERVSQN 300
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278093639 335 MVALLE-GQ-PRLLNLKQMLEAFLRHRREVVTRRTKFELKKARDRghvlegLAVALANVDEIIALIKA 400
Cdd:PHA02592 301 ITVINEnGKlKVYENAEDLIRDFVEIRKTYVQKRIQYEIKETEEA------FDLALAKAEFIKRVIAG 362
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
13-343 |
6.99e-45 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 168.92 E-value: 6.99e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 13 LEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRALFAMHELsnDWNKAYKkSARIVGDVIGkYHPHGDTAVYDTIVRM 92
Cdd:PRK09630 4 VSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFRM--DDGKMHK-VANIAGRTMA-LHPHGDAPIVEALVVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 93 AQnfslRYPLVDGQGNFGS-VDGDNAAAMRYTEIRMARIAHELLADIDkeTVDFGPNYDGSEDEPLILPAKIPNLLINGS 171
Cdd:PRK09630 80 AN----KGYLIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVLFNTD--LMTFHDSYDGREKEPDILPAKLPLLLLHGV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 172 SGIAVGMATNIPPHNLNEIVDACLAVLERPEITIdeliaivpAPDFPTAGIIYGVDgvrdgYRTGRGRVVMRAkchfeEI 251
Cdd:PRK09630 154 DGIAVGMTTKIFPHNFCELLEAQIAILNDQPFTL--------LPDFPSGGTMDASE-----YQDGLGSITLRA-----SI 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 252 DKSNGRQAIIVDELPyQVNKANLCAKIgELVREKAIEGISEIRDESDKSGmRMVVELKRGEMPEVILNNLYKHTQMQDTF 331
Cdd:PRK09630 216 DIINDKTLLIKEICP-STTTETLIRSI-ENAAKRGIIKIDSIQDFSTDLP-HIEIKLPKGIYAKDLLRPLFTHTECQVIL 292
|
330
....*....|..
gi 1278093639 332 GMNMVALLEGQP 343
Cdd:PRK09630 293 TSRPTAIYQNKP 304
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
32-492 |
5.18e-25 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 112.11 E-value: 5.18e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 32 RALPDVRDGLKPVHRRALFAMheLSNDWnKAYKKSARIVGDVI--GKYHpHGDTAVYDTIVRMAQNF------SLRYPlv 103
Cdd:PLN03128 673 RSIPSMVDGLKPSQRKVLFAC--FKRNL-KSEIKVAQLSGYVAehSAYH-HGEASLASTIIGMAQDFvgsnniNLLTP-- 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 104 dgQGNFGS--VDGDNAAAMRYTEIRMARIAHELLADIDKETVDFgPNYDGSEDEPLILPAKIPNLLINGSSGIAVGMATN 181
Cdd:PLN03128 747 --SGQFGTrlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNY-LNEDGQSIEPEWYCPIIPMVLVNGSEGIGTGWSTF 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 182 IPPHNLNEIVDACLAVLERpeitiDELIAIVP-APDFptAGIIYGVDGVRDGYRTGRGRVvmrakchfEEIDKSngrqAI 260
Cdd:PLN03128 824 IPNYNPRDIIANIRRLLRG-----EELEPMHPwYRGF--KGTITEVSTSRSGSYTVTGII--------EQIGDT----TI 884
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 261 IVDELPY----QVNKANLCAKIGELVREKAIegISEIRDESDKSGMRMVVELKRGEMPEVILNNLYKHTQMQDTFGMNMV 336
Cdd:PLN03128 885 RITELPVrkwtQDYKEFLEALLTGTKKKEPE--IKDFKENHTDTTVHFTVTLSEEKMARALAEGLEKKFKLSTTISTSNM 962
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 337 ALLEGQPRLLNLK---QMLEAFLRHR-------REVVTRRTKFELKKARDRGHVLEG-----LAVALANVDEIIALIKA- 400
Cdd:PLN03128 963 HLFDKDGKIKKYDspeDILEEFFHLRldlyvkrKEVLLENLEYELKKLDNKARFILAvvkgeIVVNNRKRAELLAELEEk 1042
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 401 --APTPADAKAGLIGRVWHSTLVEEMLSRAASGEAYRPFglvpEYGLHTDGYHLSDVQAQAILDLRLQRLTGLEQDKVLS 478
Cdd:PLN03128 1043 gfDKFPKTAKISETNVVGDRDGEASEEEEASDNELAKSY----DYLLGMPISSLTLEKVDELRAERAKKETEVEELKKTT 1118
|
490
....*....|....*..
gi 1278093639 479 E---YREVMDRITDLLD 492
Cdd:PLN03128 1119 PedlWRKDLDAFEEALD 1135
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
32-373 |
2.67e-21 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 100.12 E-value: 2.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 32 RALPDVRDGLKPVHRRALFAM--HELSNDwnkayKKSARIVGDVIGK--YHpHGDTAVYDTIVRMAQNF------SLRYP 101
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFACfkRNLKNE-----IKVAQLSGYVSEHsaYH-HGEQSLQQTIVGMAQNFvgsnniNLLYP 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 102 lvDGQgnFGS--VDGDNAAAMRYTEIRMARIAHELLADIDKETVDFgPNYDGSEDEPLILPAKIPNLLINGSSGIAVGMA 179
Cdd:PTZ00108 754 --CGQ--FGSrlQGGKDHAAARYIFTKLSKITRYIFPEEDDPILDY-LEDDGQSVEPFYYVPIIPMVLVNGAEGIGTGFS 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 180 TNIPPHNLNEIVDAclavLERpEITIDELIAIVPApdfptagiiygvdgvrdgYRTGRGRVVMRAKCHFEEID--KSNGR 257
Cdd:PTZ00108 829 TSIPNYNPLDIIDN----LRR-RLNGEEVRPLVPW------------------YRGFKGTIERNPKGKFISKGiyEKVPD 885
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 258 QAIIVDELPYQVNKANLCAKIGELVREKAiEGISEIRDESDKSGMRMVVELKRGEMPEVILNNLYKHTQMQDTFGM-NMV 336
Cdd:PTZ00108 886 GTVEITELPIGKWTEDYKEFLESETLKEK-DVIVDYRDYSTANTVHFTVKLNDGVLEQWEEEGIEKVFKLKSTISTtNMV 964
|
330 340 350
....*....|....*....|....*....|....*....
gi 1278093639 337 ALLEGQ--PRLLNLKQMLEAFLRHRREVVTRRTKFELKK 373
Cdd:PTZ00108 965 LFDENGkiKKYSDALDILKEFYLVRLDLYKKRKEYLLGK 1003
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
32-373 |
1.47e-16 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 84.91 E-value: 1.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 32 RALPDVRDGLKPVHRRALFAmhelsnDWNKAYKKSARI---VGDV--IGKYHpHGDTAVYDTIVRMAQNF--SLRYPLVD 104
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFC------SFKRNFVKEAKVaqlSGYVseHSAYH-HGEQSLASTIIGMAQDFvgSNNINLLL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 105 GQGNFG--SVDGDNAAAMRYTEIRMARIAHELLADIDKETVDFgPNYDGSEDEPLILPAKIPNLLINGSSGIAVGMATNI 182
Cdd:PLN03237 771 PNGQFGtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDY-LNEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWSTFI 849
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 183 PPHNLNEIVDACLAVL--ERPEI----------TIDELIAivpapdfPTAGIIYGVDGVrdgyrtgrgrvvmrakchFEE 250
Cdd:PLN03237 850 PNYNPRDIVANIRRLLngESMEPmhpwyrgfkgTIEKTAS-------KEGGCTYTITGL------------------YEE 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278093639 251 IDKSNgrqaIIVDELP---YQVNKANLCAKIGELVREKAIEGISEIRDESDKSGMRMVVELKRGEM----PEVILNNlYK 323
Cdd:PLN03237 905 VDETT----LRITELPirrWTDDYKEFLESLKTDNNKNKDPFIKDVKAYNDDTTVHFEVILSEENMlaakQEGLLKK-FK 979
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1278093639 324 HTQMQDTFGMNMVALLEGQPRLLNLKQMLEAF--LR-----HRREVVTRRTKFELKK 373
Cdd:PLN03237 980 LTTTISTSNMHLFDSKGVIKKYDTPEQILEEFfhLRleyyeKRKEVLLKNLEFELLK 1036
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
796-842 |
2.72e-12 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 61.73 E-value: 2.72e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1278093639 796 DEIMLITTGGVLIRTRVSEIREMGRTTQGVTLINLDKGERLSGLQRV 842
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
590-640 |
2.85e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 56.34 E-value: 2.85e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1278093639 590 DYILCFTDRGRMFWLKVYEVPQGGRVSRGKPIVNllkLDEGEKVTAILPVK 640
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN---LKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
540-587 |
1.25e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.33 E-value: 1.25e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1278093639 540 DVMVTLSNTGYIKSQPIDEYRTQKRGGRGKQAAATKEEDFIESLFVAN 587
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
694-741 |
1.58e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.33 E-value: 1.58e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1278093639 694 HDVMLFTDAGKANRFDENDVRPTGRDSRGVRGVRLPVHGKVIALLVAE 741
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
745-793 |
1.64e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.33 E-value: 1.64e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1278093639 745 QSVLTATENGYGKRTPVAEYTRHNRGGQGMIAIQTSErNGKVVAATLVE 793
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKE-GDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
646-691 |
7.12e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 49.41 E-value: 7.12e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1278093639 646 HYIFMATANGTVKKTALSEFSRPRSN--GIIAVRLDDGDYLIGVAITD 691
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGakGVKGINLKEGDKVVSVLVVN 48
|
|
| |
