|
Name |
Accession |
Description |
Interval |
E-value |
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
118-476 |
2.06e-80 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 253.95 E-value: 2.06e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 118 RLRQNTLAIPAELDGAEKSVLEERLRSMGKELTDLAEKTSLTERRAIRTLLQATRNILIFSTFALLALAIAITTILGRNV 197
Cdd:COG4191 2 LRLLLLLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 198 VRSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAFNRMLNELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNIS 277
Cdd:COG4191 82 LGLLLLLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRELQEQLVQSEKLAALGELAAGIAHEINNPLAAIL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 278 TSAQILGEEIA-EGDLEFKKSLIAQIEGQSDKARDIVRSLLEFSRIREVRKERLLLARLLAETVLLIRGQVPSK-VDIAI 355
Cdd:COG4191 162 GNAELLRRRLEdEPDPEELREALERILEGAERAAEIVRSLRAFSRRDEEEREPVDLNELIDEALELLRPRLKARgIEVEL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 356 DIPDDL-EIVADKQRIQQVFLNLIKNAVDVVGDK--GHIWVAARKIKEtpdhkmEVEILIEDDGPGIEPENLKLIFDPFF 432
Cdd:COG4191 242 DLPPDLpPVLGDPGQLEQVLLNLLINAIDAMEEGegGRITISTRREGD------YVVISVRDNGPGIPPEVLERIFEPFF 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1278273719 433 TTKDVGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:COG4191 316 TTKPVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLP 359
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
241-476 |
6.21e-71 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 229.35 E-value: 6.21e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 241 ELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLefkKSLIAQIEGQSDKARDIVRSLLEFS 320
Cdd:COG3852 118 ERKRLERELRRAEKLAAVGELAAGLAHEIRNPLTGIRGAAQLLERELPDDEL---REYTQLIIEEADRLNNLVDRLLSFS 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 321 RIREVRKERLLLARLLAETVLLIRGQVPSKVDIAIDIPDDL-EIVADKQRIQQVFLNLIKNAVDVVGDKGHI----WVAA 395
Cdd:COG3852 195 RPRPPEREPVNLHEVLERVLELLRAEAPKNIRIVRDYDPSLpEVLGDPDQLIQVLLNLVRNAAEAMPEGGTItirtRVER 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 396 RKIKETPDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDvgRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWL 475
Cdd:COG3852 275 QVTLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKE--KGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYL 352
|
.
gi 1278273719 476 P 476
Cdd:COG3852 353 P 353
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
114-476 |
3.44e-62 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 208.28 E-value: 3.44e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 114 DSMLRLRQNTLAIPAELDGA-EKSVLEERLRSMGKELTDLAEKtsLTERRA-IRTLLQ----------ATRNILIFSTFA 181
Cdd:COG5000 42 EATRAVAAGDLSVRLPVTGDdEIGELARAFNRMTDQLKEQREE--LEERRRyLETILEnlpagvivldADGRITLANPAA 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 182 LLALAIAITTILGR---NVVRSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAFNRMLNELKLRQE--QLVQSEKLA 256
Cdd:COG5000 120 ERLLGIPLEELIGKpleELLPELDLAELLREALERGWQEEIELTRDGRRTLLVRASPLRDDGYVIVFDDitELLRAERLA 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 257 ALGTLLSGVAHELNNPLSNISTSAQIL----GEEIAEGDLEFKKSLiAQIEGQSDKARDIVRSLLEFSRIREVRKERLLL 332
Cdd:COG5000 200 AWGELARRIAHEIKNPLTPIQLSAERLrrklADKLEEDREDLERAL-DTIIRQVDRLKRIVDEFLDFARLPEPQLEPVDL 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 333 ARLLAETVLLIR-GQVPSKVDIAIDIPDDL-EIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKIKEtpdhkmEVEI 410
Cdd:COG5000 279 NELLREVLALYEpALKEKDIRLELDLDPDLpEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDG------RVRI 352
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278273719 411 LIEDDGPGIEPENLKLIFDPFFTTKDvgRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:COG5000 353 EVSDNGPGIPEEVLERIFEPFFTTKP--KGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLP 416
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
241-476 |
1.12e-51 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 175.10 E-value: 1.12e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 241 ELKLRQEQLVQSEKLaaLGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDlEFKKSLIAQIEGQSDKARDIVRSLLEFS 320
Cdd:COG2205 1 ELEEALEELEELERL--KSEFLANVSHELRTPLTSILGAAELLLDEEDLSP-EERRELLEIIRESAERLLRLIEDLLDLS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 321 RIR----EVRKERLLLARLLAETVLLIRGQVPSK-VDIAIDIPDDL-EIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVA 394
Cdd:COG2205 78 RLEsgklSLELEPVDLAELLEEAVEELRPLAEEKgIRLELDLPPELpLVYADPELLEQVLANLLDNAIKYSPPGGTITIS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 395 ARKIKEtpdhkmEVEILIEDDGPGIEPENLKLIFDPFFTTKDVGR--GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFI 472
Cdd:COG2205 158 ARREGD------GVRISVSDNGPGIPEEELERIFERFYRGDNSRGegGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFT 231
|
....
gi 1278273719 473 IWLP 476
Cdd:COG2205 232 VTLP 235
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
161-476 |
1.42e-51 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 177.79 E-value: 1.42e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 161 RRAIRTLLQATRNILIFSTFALLALAIAITTILGRNVVRSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAFNRMLN 240
Cdd:COG0642 13 LLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 241 ELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFkkslIAQIEGQSDKARDIVRSLLEFS 320
Cdd:COG0642 93 LLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELDEEQREY----LETILRSADRLLRLINDLLDLS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 321 RIREVRKERLLL----ARLLAETVLLIRGQVPSK-VDIAIDIPDDLEIV-ADKQRIQQVFLNLIKNAVDVVGDKGHIWVA 394
Cdd:COG0642 169 RLEAGKLELEPEpvdlAELLEEVVELFRPLAEEKgIELELDLPDDLPTVrGDPDRLRQVLLNLLSNAIKYTPEGGTVTVS 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 395 ARKIKETpdhkmeVEILIEDDGPGIEPENLKLIFDPFFTTKDVGR--GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFI 472
Cdd:COG0642 249 VRREGDR------VRISVEDTGPGIPPEDLERIFEPFFRTDPSRRggGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFT 322
|
....
gi 1278273719 473 IWLP 476
Cdd:COG0642 323 VTLP 326
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
223-476 |
7.06e-49 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 177.08 E-value: 7.06e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 223 VHDQEIVSLLTAfnRMLNELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAegDLEFKKSLiAQI 302
Cdd:PRK11360 357 THGEMIGALVIF--SDLTERKRLQRRVARQERLAALGELVAGVAHEIRNPLTAIRGYVQIWRQQTS--DPPSQEYL-SVV 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 303 EGQSDKARDIVRSLLEFSRIREVRKERLLLARLLAETVLLIR-GQVPSKVDIAIDIPDDLE-IVADKQRIQQVFLNLIKN 380
Cdd:PRK11360 432 LREVDRLNKVIDQLLEFSRPRESQWQPVSLNALVEEVLQLFQtAGVQARVDFETELDNELPpIWADPELLKQVLLNILIN 511
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 381 AVDVVGDKGHIWVAARKIKETpdhkmEVEILIEDDGPGIEPENLKLIFDPFFTTKDvgRGSGLGLFVVHNIIEWHGGTIT 460
Cdd:PRK11360 512 AVQAISARGKIRIRTWQYSDG-----QVAVSIEDNGCGIDPELLKKIFDPFFTTKA--KGTGLGLALSQRIINAHGGDIE 584
|
250
....*....|....*.
gi 1278273719 461 VDSRPGLGTTFIIWLP 476
Cdd:PRK11360 585 VESEPGVGTTFTLYLP 600
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
199-476 |
1.10e-47 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 168.43 E-value: 1.10e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 199 RSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAFnRMLNELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNIST 278
Cdd:COG5807 89 AFDRIEISYLTKNGEFDEIIYPIYYKDGVILGLITVY-RDITKRKEAEDKLLRSEKLSVAGELAAGIAHEIRNPLTSIKG 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 279 SAQILGEEIAEGDLEFKKSLIAQiegQSDKARDIVRSLLEFSRIREVRKERLLLARLLAETVLLIRGQVPSK-VDIAIDI 357
Cdd:COG5807 168 FLQLLQESREDSEREEYFNIIIS---EIDRINTIITELLVLSKPKKFNFKKLNLNDVLEDVIALLSTEAILKnISIKYDL 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 358 PDDL-EIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKIKEtpdhkmEVEILIEDDGPGIEPENLKLIFDPFFTTKD 436
Cdd:COG5807 245 ADDEpVINGDKNQLKQVFINLIKNAIEAMETGGNITIKTYVEGD------FVVISVKDEGIGIPEEVLEKIGEPFFTTKE 318
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1278273719 437 vgRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:COG5807 319 --EGTGLGLSICKKIIEEHNGTIEVESKPGKGTTFTIYLP 356
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
230-476 |
1.34e-47 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 170.74 E-value: 1.34e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 230 SLLTAF--NRMLNELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDlefKKSLIAQI-EGQS 306
Cdd:PRK10364 207 SLLAFFwyRRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGG---EAHQLAQVmAKEA 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 307 DKARDIVRSLLEFSRIREVRKERLLLARLLAETVLLIRGQVPSK-VDIAIDIPDDLE-IVADKQRIQQVFLNLIKNAVDV 384
Cdd:PRK10364 284 DRLNRVVSELLELVKPTHLALQAVDLNDLINHSLQLVSQDANSReIQLRFTANDTLPeIQADPDRLTQVLLNLYLNAIQA 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 385 VGDKGHIWVAARKiketpdHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKdvGRGSGLGLFVVHNIIEWHGGTITVDSR 464
Cdd:PRK10364 364 IGQHGVISVTASE------SGAGVKISVTDSGKGIAADQLEAIFTPYFTTK--AEGTGLGLAVVHNIVEQHGGTIQVASQ 435
|
250
....*....|..
gi 1278273719 465 PGLGTTFIIWLP 476
Cdd:PRK10364 436 EGKGATFTLWLP 447
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
195-483 |
1.55e-44 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 162.84 E-value: 1.55e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 195 RNVVRSLKILENYTRRISK-GERKEADIK---VHDQEIVSLLTAFNRMLNELKLRQEQLVQSEKLAALGTLLSGVAHELN 270
Cdd:COG5809 203 SQLLKDGGIAQGEVRFWTKdGRWRLLEASgapIKKNGEVDGIVIIFRDITERKKLEELLRKSEKLSVVGELAAGIAHEIR 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 271 NPLSNISTSAQILGEEIAEGdlefKKSLIAQIEGQSDKARDIVRSLLEFSRIREVRKERLLLARLLAETVLLIRGQVPSK 350
Cdd:COG5809 283 NPLTSLKGFIQLLKDTIDEE----QKTYLDIMLSELDRIESIISEFLVLAKPQAIKYEPKDLNTLIEEVIPLLQPQALLK 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 351 -VDIAIDIPDDL-EIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVaarKIKETPDHKmeVEILIEDDGPGIEPENLKLIF 428
Cdd:COG5809 359 nVQIELELEDDIpDILGDENQLKQVFINLLKNAIEAMPEGGNITI---ETKAEDDDK--VVISVTDEGCGIPEERLKKLG 433
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1278273719 429 DPFFTTKDvgRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLPGGQEELP 483
Cdd:COG5809 434 EPFYTTKE--KGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPIKLSEQV 486
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
117-476 |
3.62e-44 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 159.72 E-value: 3.62e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 117 LRLRQNTLAIPAELDGAEKSVLEERLRSMGKELTDLAEKTSLTERRAIRTLLQATRNILIFSTFALLALAIAITTILGRN 196
Cdd:COG5002 33 LLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 197 VVRSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAFNRMLNELKlRQEQLvQSEklaalgtLLSGVAHELNNPLSNI 276
Cdd:COG5002 113 LLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELE-RLEQM-RRE-------FVANVSHELRTPLTSI 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 277 STSAQILgEEIAEGDLEFKKSLIAQIEGQSDKARDIVRSLLEFSRI----REVRKERLLLARLLAETVLLIRGQVPSK-V 351
Cdd:COG5002 184 RGYLELL-LDGAADDPEERREYLEIILEEAERLSRLVNDLLDLSRLesgeLKLEKEPVDLAELLEEVVEELRPLAEEKgI 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 352 DIAIDIPDD-LEIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKIKEtpdhkmEVEILIEDDGPGIEPENLKLIFDP 430
Cdd:COG5002 263 ELELDLPEDpLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDD------QVRISVRDTGIGIPEEDLPRIFER 336
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1278273719 431 FFTTkDVGR-----GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:COG5002 337 FYRV-DKSRsretgGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLP 386
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
246-476 |
2.48e-39 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 151.75 E-value: 2.48e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 246 QEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAqilgeEIAEGDLEFKKSL---IAQIEGQSDKARDIVRSLLEFSRI 322
Cdd:PRK13837 438 ERRLEHARRLEAVGTLASGIAHNFNNILGAILGYA-----EMALNKLARHSRAaryIDEIISAGARARLIIDQILAFGRK 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 323 REVRKERLLLARLLAETVLLIRGQVPSKVDIAIDIPDDLEIV-ADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKIK-E 400
Cdd:PRK13837 513 GERNTKPFDLSELVTEIAPLLRVSLPPGVELDFDQDQEPAVVeGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRAKlR 592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 401 TPDHKME--------VEILIEDDGPGIEPENLKLIFDPFFTTKdvGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFI 472
Cdd:PRK13837 593 APKVLSHgvlppgryVLLRVSDTGAGIDEAVLPHIFEPFFTTR--AGGTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFD 670
|
....
gi 1278273719 473 IWLP 476
Cdd:PRK13837 671 VYLP 674
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
2-480 |
6.57e-38 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 144.93 E-value: 6.57e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 2 RLSFSIRQKITYGFSLLLIFMIGTALLTYGLVRRVERKVLFVEVIDDFFNATLEARRFEKNYFLYGQGKDLRENLFYWRK 81
Cdd:COG4251 28 LLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLELALVLLALLLVLLLLLALL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 82 LDDLLRDNQEAFAAAVTTGGLANLREKVDGYHDSMLRLRQNTLAIPAELDGAEKSVLEERLRSMGKELTDLAEKTSLTER 161
Cdd:COG4251 108 LLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLV 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 162 RAIRTLLQATRNILIFSTFALLALAIAITTILGRNVVRSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAFNRMLNE 241
Cdd:COG4251 188 LLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEE 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 242 LKLRQEQLVQSEKlaALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFKKSLIAQIEGQSDKARDIVRSLLEFSR 321
Cdd:COG4251 268 LEERTAELERSNE--ELEQFAYVASHDLREPLRKISGFSQLLEEDYGDKLDEEGREYLERIRDAAERMQALIDDLLAYSR 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 322 I--REVRKERLLLARLLAETVLLIRGQVPSKvDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVD--VVGDKGHIWVAARK 397
Cdd:COG4251 346 VgrQELEFEPVDLNELLEEVLEDLEPRIEER-GAEIEVGPLPTVRGDPTLLRQVFQNLISNAIKysRPGEPPRIEIGAER 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 398 IKEtpdhkmEVEILIEDDGPGIEPENLKLIFDPFFT--TKDVGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWL 475
Cdd:COG4251 425 EGG------EWVFSVRDNGIGIDPEYAEKIFEIFQRlhSRDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTL 498
|
....*
gi 1278273719 476 PGGQE 480
Cdd:COG4251 499 PKAPA 503
|
|
| T2SS_HK |
NF038348 |
histidine kinase; |
237-476 |
6.69e-38 |
|
histidine kinase;
Pssm-ID: 439642 [Multi-domain] Cd Length: 574 Bit Score: 145.86 E-value: 6.69e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 237 RMLNELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLS----NIST----------------------SAQILGEEIAEG 290
Cdd:NF038348 306 RLIHELEETHVQLLQSEKLASIGQLAAGVAHEINNPIGfvsaNLNTlkgwvhslldviaaqeaatpahAAQTRAPLAAAG 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 291 ---DLEFKKSLIA-----QIEGqSDKARDIVRSLLEFSRIREVRKERLLLARLLAETVLLIRGQVPSKVDIAIDIPDDLE 362
Cdd:NF038348 386 rdaDLDYVRGDIMtlideSIDG-AMRVRRIVQDLRDFSRPSGDEWSFADLHAGLESTLNVVHNELKYKADVVREYGDLPL 464
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 363 IVADKQRIQQVFLNLIKNAVDVVGDKGHIWVaarkikETPDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDVGRGSG 442
Cdd:NF038348 465 VECNAAQLNQVFMNLLVNAAQAIPGRGTITI------RTTCDGDHASIAISDTGKGIPPDVMGRIFDPFFTTKPVGQGTG 538
|
250 260 270
....*....|....*....|....*....|....
gi 1278273719 443 LGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:NF038348 539 LGLSISHGIVEHHRGRIDVASEPGRGSTFTITLP 572
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
241-476 |
2.99e-37 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 142.95 E-value: 2.99e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 241 ELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIaEGDLEFKKSLIAQIegqsDKARDIVRSLLEFS 320
Cdd:COG5805 270 EKKEAEELMARSEKLSIAGQLAAGIAHEIRNPLTSIKGFLQLLQPGI-EDKEEYFDIMLSEL----DRIESIISEFLALA 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 321 RIREVRKERLLLARLLAETVLLIRGQ--VPSKVDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAArki 398
Cdd:COG5805 345 KPQAVNKEKENINELIQDVVTLLETEaiLHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHT--- 421
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278273719 399 kETPDHKmeVEILIEDDGPGIEPENLKLIFDPFFTTKDvgRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:COG5805 422 -EEEDNS--VIIRVIDEGIGIPEERLKKLGEPFFTTKE--KGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLP 494
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
225-480 |
3.75e-35 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 136.42 E-value: 3.75e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 225 DQEIVSLLTAFNRMLNELKL-RQEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFKKSLIAQie 303
Cdd:COG5808 207 LISIIFLLLQYNLLKRKTLLeRVIQEINTQKLELIGTFAASTAHEIRNPLTSIKGFIQLLQEKYPELEDQKYFDIIQE-- 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 304 gQSDKARDIVRSLLEFSRIREVRKERLLLARLLAETVLLIRGQ-VPSKVDIAIDIPDD-LEIVADKQRIQQVFLNLIKNA 381
Cdd:COG5808 285 -EIQRINQIVSEFLVLGKPTAKKLELDDLNELIEEILSIIDSEaNLKNIRVEKQSLDEpLHIKCDKDRIKQVLLNLIKNA 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 382 VDVVGDKGHIWVAARKIKEtpdhkmEVEILIEDDGPGIEPENLKLIFDPFFTTKDvgRGSGLGLFVVHNIIEWHGGTITV 461
Cdd:COG5808 364 IEAMKEGGKLTISIENDDE------KAVIEVIDNGEGIPEDIIDEIFEPFVTTKE--GGTGLGLSVCKRIVEMHGGEIDI 435
|
250
....*....|....*....
gi 1278273719 462 DSRPGLGTTFIIWLPGGQE 480
Cdd:COG5808 436 ESEEGKGTTFTIRLPLKKE 454
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
237-476 |
2.12e-34 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 133.45 E-value: 2.12e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 237 RMLNELKLRQEqLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGE--EIAEGDLEFKKSLIAQIegqsDKARDIVR 314
Cdd:COG5806 181 NLIENILLRKE-LQRAEKLEVVSELAASIAHEVRNPLTVVRGFIQLLQEpeLSDEKRKQYIRIALEEL----DRAEAIIT 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 315 SLLEFSRIREVRKERLLLARLLAETVLLIRgqvP----SKVDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVDVVGDKGH 390
Cdd:COG5806 256 DYLTFAKPQPEKLEKIDVSEELEHVIDVLS---PyanmNNVEIQTELEPGLYIEGDRQKLQQCLINIIKNGIEAMPNGGT 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 391 IWVAARKIKETpdhkmeVEILIEDDGPGIEPENLKLIFDPFFTTKdvGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTT 470
Cdd:COG5806 333 LTIDVSIDKNK------VIISIKDTGVGMTKEQLERLGEPYFSTK--EKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTT 404
|
....*.
gi 1278273719 471 FIIWLP 476
Cdd:COG5806 405 FTITLP 410
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-476 |
1.02e-33 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 122.92 E-value: 1.02e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGDKGHIWVaarkikETPDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDVGRGSGLGLFVVH 449
Cdd:cd16943 4 LNQVLLNLLVNAAQAMEGRGRITI------RTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEGTGLGLSLSY 77
|
90 100
....*....|....*....|....*..
gi 1278273719 450 NIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16943 78 RIIQKHGGTIRVASVPGGGTRFTIILP 104
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
365-476 |
1.16e-33 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 122.76 E-value: 1.16e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 365 ADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKiketpdHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDVGR---GS 441
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLER------DGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRkigGT 74
|
90 100 110
....*....|....*....|....*....|....*
gi 1278273719 442 GLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:smart00387 75 GLGLSIVKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
365-476 |
8.79e-31 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 114.77 E-value: 8.79e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 365 ADKQRIQQVFLNLIKNAVDVVGDKGHIWVaarkikeTPDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDV-GRGSGL 443
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITV-------TLSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRgGGGTGL 73
|
90 100 110
....*....|....*....|....*....|...
gi 1278273719 444 GLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:pfam02518 74 GLSIVRKLVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
370-475 |
5.26e-30 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 112.70 E-value: 5.26e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGDKGHIWVAARKIKEtpdhkmEVEILIEDDGPGIEPENLKLIFDPFFTTKDV--GRGSGLGLFV 447
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGD------GVVLEVEDNGPGIPEEDLERIFERFYRGDKSreGGGTGLGLAI 74
|
90 100
....*....|....*....|....*...
gi 1278273719 448 VHNIIEWHGGTITVDSRPGLGTTFIIWL 475
Cdd:cd00075 75 VRRIVEAHGGRITVESEPGGGTTFTVTL 102
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
112-463 |
8.32e-29 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 119.79 E-value: 8.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 112 YHDSMLRLRQNTLAIPAELDGAEKSVlEERLRSMGKELTDLAEKTSLTERRAIRTLLQATR--NILIFSTFAL-LALAIA 188
Cdd:COG4192 263 GEGGLPSLRRDELAAQATLEALAEEN-NSILEQLRTQISGLVGNSREQLVALNQETAQLVQqsGILLLAIALLsLLLAVL 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 189 ITTIL-GRNVVRSLKILENYTRRISKGErKEADIKV--HDQ--EIVSLLTAF----------------NRMLNELKLRQE 247
Cdd:COG4192 342 INYFYvRRRLVKRLNALSDAMAAIAAGD-LDVPIPVdgNDEigRIARLLRVFrdqaiektqeleteieERKRIEKNLRQT 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 248 Q--LVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFKKSLIAQIEGQSDKARDIVRSLLEFSRIREV 325
Cdd:COG4192 421 QdeLIQAAKMAVVGQTMTSLAHELNQPLNAMSMYLFSAKKALEQENYAQLPTSLDKIEGLIERMDKIIKSLRQFSRKSDT 500
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 326 RKERLLLARLLAETVLLIRGQVPSKvDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAarkIKETPDHk 405
Cdd:COG4192 501 PLQPVDLRQVIEQAWELVESRAKPQ-QITLHIPDDLMVQGDQVLLEQVLVNLLVNALDAVATQPQISVD---LLSNAEN- 575
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1278273719 406 meVEILIEDDGPGIepENLKLIFDPFFTTKDVGRgsGLGLFVVHNIIEWHGGTITVDS 463
Cdd:COG4192 576 --LRVAISDNGNGW--PLVDKLFTPFTTTKEVGL--GLGLSICRSIMQQFGGDLYLAS 627
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-471 |
7.80e-27 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 104.08 E-value: 7.80e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGD--KGHIWVAARKIKEtpdhkmEVEILIEDDGPGIEPENLKLIFDPFFTTKDVGRGSGLGLFV 447
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKveNPRIRIAARRLGG------RLVLVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGTGLGLSI 74
|
90 100
....*....|....*....|....
gi 1278273719 448 VHNIIEWHGGTITVDSRPGLGTTF 471
Cdd:cd16976 75 SYGIVEEHGGRLSVANEEGAGARF 98
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
246-482 |
2.09e-26 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 112.07 E-value: 2.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 246 QEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFKKSLIA--QIEGQSDKARDIVRSLLEFSRIR 323
Cdd:PRK13557 151 EDALRQAQKMEALGQLTGGIAHDFNNLLQVMSGYLDVIQAALSHPDADRGRMARSveNIRAAAERAATLTQQLLAFARKQ 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 324 EVRKERLLLARLLAETVLLIRGQVPSKVDIAIDIPDDL---EIvaDKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKIK- 399
Cdd:PRK13557 231 RLEGRVLNLNGLVSGMGELAERTLGDAVTIETDLAPDLwncRI--DPTQAEVALLNVLINARDAMPEGGRVTIRTRNVEi 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 400 ETPDHKME--------VEILIEDDGPGIEPENLKLIFDPFFTTKDVGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTF 471
Cdd:PRK13557 309 EDEDLAMYhglppgryVSIAVTDTGSGMPPEILARVMDPFFTTKEEGKGTGLGLSMVYGFAKQSGGAVRIYSEVGEGTTV 388
|
250
....*....|.
gi 1278273719 472 IIWLPGGQEEL 482
Cdd:PRK13557 389 RLYFPASDQAE 399
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
231-476 |
3.90e-26 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 109.01 E-value: 3.90e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 231 LLTAFNRMLNELKLRQEQLVQSEKLAAlGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDL-EFKKSLIAQiegqSDKA 309
Cdd:PRK11073 104 ILLEMAPMDNQRRLSQEQLQHAQQVAA-RDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALtEYTKVIIEQ----ADRL 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 310 RDIVRSLL--------EFSRIREV-RKERLLLARLLAETVLLIRGQVPSKVDIAIDiPDdleivadkqRIQQVFLNLIKN 380
Cdd:PRK11073 179 RNLVDRLLgpqrpgthVTESIHKVaERVVQLVSLELPDNVRLIRDYDPSLPELAHD-PD---------QIEQVLLNIVRN 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 381 AVDVVGDK-GHIWVAARKIKETPDH----KMEVEILIEDDGPGIEPENLKLIFDPFFTTKDvgRGSGLGLFVVHNIIEWH 455
Cdd:PRK11073 249 ALQALGPEgGTITLRTRTAFQLTLHgeryRLAARIDIEDNGPGIPPHLQDTLFYPMVSGRE--GGTGLGLSIARNLIDQH 326
|
250 260
....*....|....*....|.
gi 1278273719 456 GGTITVDSRPGlGTTFIIWLP 476
Cdd:PRK11073 327 SGKIEFTSWPG-HTEFSVYLP 346
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
170-476 |
2.22e-25 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 108.39 E-value: 2.22e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 170 ATRNILIFSTFALLALAIAITTILGRNVVRSLKILENYTRRISKGERKEADiKVHDQEIVSLLTAFNRMLNELKLRQ--E 247
Cdd:PRK11100 179 RSERRILWAGALLLGIALLIGAGVVWWLNRSIRRLTRYADAVTEGKPVPLP-KLGSSELRELAQALESMRVKLEGKAyvE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 248 QLVQseklaalgTLlsgvAHELNNPLSNISTSAQILGEEIAEGDLEFkksLIAQIEGQSDKARDIVRSLLEFSRIrEVRK 327
Cdd:PRK11100 258 QYVQ--------TL----THELKSPLAAIRGAAELLQEDPPPEDRAR---FTGNILTQSARLQQLIDRLLELARL-EQRQ 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 328 ERLLLARLLAETVL--LIRGQVPS----KVDIAIDiPDDLEIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKiket 401
Cdd:PRK11100 322 ELEVLEPVALAALLeeLVEAREAQaaakGITLRLR-PDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEV---- 396
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1278273719 402 pdHKMEVEILIEDDGPGIePE-NLKLIFDPFFTT--KDVGR-GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:PRK11100 397 --DGEQVALSVEDQGPGI-PDyALPRIFERFYSLprPANGRkSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLP 472
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
371-476 |
1.61e-24 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 97.84 E-value: 1.61e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 371 QQVFLNLIKNAVDVVGDKGHIWVAARKIKETPDHKME---------VEILIEDDGPGIEPENLKLIFDPFFTTKDVGRGS 441
Cdd:cd16919 2 ELAILNLAVNARDAMPEGGRLTIETSNQRVDADYALNyrdlipgnyVCLEVSDTGSGMPAEVLRRAFEPFFTTKEVGKGT 81
|
90 100 110
....*....|....*....|....*....|....*
gi 1278273719 442 GLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16919 82 GLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
242-476 |
1.19e-23 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 102.34 E-value: 1.19e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 242 LKLRQEQLVQSEKLAALGTLLSGVAHELNNPLS--NISTSAQILG--EEIAEGDLEFKKSLIAQIEGQSDKARDIVRSLL 317
Cdd:PRK09303 135 FVLRQENETLLEQLKFKDRVLAMLAHDLRTPLTaaSLALETLELGqiDEDTELKPALIEQLQDQARRQLEEIERLITDLL 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 318 EFSRIRE----VRKERLLLARLLAETVLLIRGQVPSK-VDIAIDIPDDLEIV-ADKQRIQQVFLNLIKNAVDVVGDKGHI 391
Cdd:PRK09303 215 EVGRTRWealrFNPQKLDLGSLCQEVILELEKRWLAKsLEIQTDIPSDLPSVyADQERIRQVLLNLLDNAIKYTPEGGTI 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 392 WVAARkiketpdHKM--EVEILIEDDGPGIEPENLKLIF-DPFFTTKDVGR-GSGLGLFVVHNIIEWHGGTITVDSRPGL 467
Cdd:PRK09303 295 TLSML-------HRTtqKVQVSICDTGPGIPEEEQERIFeDRVRLPRDEGTeGYGIGLSVCRRIVRVHYGQIWVDSEPGQ 367
|
....*....
gi 1278273719 468 GTTFIIWLP 476
Cdd:PRK09303 368 GSCFHFTLP 376
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-476 |
1.75e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 92.08 E-value: 1.75e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGDK-GHIWVAARKIKET----PDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDvgRGSGLG 444
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSgGEIILRTRTQRQVtlghPRHRLALRVSVIDNGPGIPPDLQDTIFYPMVSGRE--NGTGLG 78
|
90 100 110
....*....|....*....|....*....|..
gi 1278273719 445 LFVVHNIIEWHGGTITVDSRPGlGTTFIIWLP 476
Cdd:cd16918 79 LAIAQNIVSQHGGVIECDSQPG-HTVFSVSLP 109
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-476 |
2.24e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 91.69 E-value: 2.24e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGDKGhiwVAARK--IKETPDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKdvGRGSGLGLFV 447
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEGG---CERREltIRTSPADDRAVTISVKDTGPGIAEEVAGQLFDPFYTTK--SEGLGMGLSI 75
|
90 100
....*....|....*....|....*....
gi 1278273719 448 VHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16920 76 CRSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
2-476 |
2.41e-22 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 99.38 E-value: 2.41e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 2 RLSFSIRQKITYGFSLLLIFMIGTALLTYGLVRRverkvlFVEVIDDFFNATLEA-RRFEKNYFLYGQGKDLREnlfywR 80
Cdd:TIGR01386 1 PRSLTLRLALLFAAVTALVFALSGFMLYSSLERH------FEERDREELQGKLEQvRRFLRDPADLDEDIKRLQ-----E 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 81 KLDDLLRDNQEAFAAAVTTGGlanlREKVDGYHDSMLRLRQNTLAIPAELDGAEKSVLEERLRS------MGKELTDLAE 154
Cdd:TIGR01386 70 KIDDLLVGHSDLALSILNPDG----RLLFERAQGAALVPAVAANDALLELDQADAKMTHYRSILrsvaalPGGKGRKPVQ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 155 KTSLTERRAIRTLLQATRNILIfstfALLALAIAITTILGRNVVR-SLKILENYTRRISKGERKEADIKVHDQ----EIV 229
Cdd:TIGR01386 146 ITVALDINAHTHLLDALRKWLI----LIAVLLVLLTALLGWWITRlGLEPLRRLSAVAARISPESLDQRLDPSrapaELR 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 230 SLLTAFNRMLNELklrqEQLVQseKLAALGtllSGVAHELNNPLSNISTSAQIL---------GEEIAEGDLEFKKSLIA 300
Cdd:TIGR01386 222 ELAQSFNAMLGRL----EDAFQ--RLSQFS---ADLAHELRTPLTNLLGQTQVAlsqprtgeeYREVLESNLEELERLSR 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 301 QIEGQSDKAR-DIVRSLLEFSRIR---EVRKERLLLARllaetvllirgqVPSKVDIAIDIPDDLEIVADKQRIQQVFLN 376
Cdd:TIGR01386 293 MVSDMLFLARaDNGQLALERVRLDlaaELAKVAEYFEP------------LAEERGVRIRVEGEGLVRGDPQMFRRAISN 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 377 LIKNAVDVVGDKGHIWVaarKIKETPDHkmeVEILIEDDGPGIEPENLKLIFDPFF----TTKDVGRGSGLGLFVVHNII 452
Cdd:TIGR01386 361 LLSNALRHTPDGGTITV---RIERRSDE---VRVSVSNPGPGIPPEHLSRLFDRFYrvdpARSNSGEGTGLGLAIVRSIM 434
|
490 500
....*....|....*....|....
gi 1278273719 453 EWHGGTITVDSRPGlGTTFIIWLP 476
Cdd:TIGR01386 435 EAHGGRASAESPDG-KTRFILRFP 457
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
370-476 |
3.91e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 91.02 E-value: 3.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVgDKGHIWVAARKIKETPDHKMeVEILIEDDGPGIEPENLKLIFDPFF-----TTKDVGrGSGLG 444
Cdd:cd16922 1 LRQILLNLLGNAIKFT-EEGEVTLRVSLEEEEEDGVQ-LRFSVEDTGIGIPEEQQARLFEPFSqadssTTRKYG-GTGLG 77
|
90 100 110
....*....|....*....|....*....|..
gi 1278273719 445 LFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16922 78 LAISKKLVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
137-476 |
9.79e-20 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 92.78 E-value: 9.79e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 137 VLEERLRSMGKELTDLAEKTSLTERrAIRTLLQAtrniLIFSTFALLALAIAITTILGRNVVRSLkilENYTRRISKGER 216
Cdd:PRK15347 266 VLRTQLKGPGWQQVTLYPRRNLANE-ALKPALQQ----LPFALLILVLLTSVLFLLLRRYLAKPL---WRFVDIINKTGP 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 217 KEADIKVHDQ---EIVSLLTAFNRMLNELKlrqEQLVQSEKLAALGTL-------------------LSGVAHELNNPLS 274
Cdd:PRK15347 338 AALEPRLPENrldELGSIAKAYNQLLDTLN---EQYDTLENKVAERTQalaeakqraeqankrksehLTTISHEIRTPLN 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 275 NIStsaqilgeeiaeGDLEFKK--SLIAQIEGQSDKARDIVRSLLE-------FSRIR----EVRKERLLLARLLAETVL 341
Cdd:PRK15347 415 GVL------------GALELLQntPLTAEQMDLADTARQCTLSLLAiinnlldFSRIEsgqmTLSLEETALLPLLDQAML 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 342 LIRGQVPSK-----VDIAIDIPddLEIVADKQRIQQVFLNLIKNAVDVVgDKGHIWVAARKIKETpdhkmeVEILIEDDG 416
Cdd:PRK15347 483 TIQGPAQSKsltlrTFVGAHVP--LYLHLDSLRLRQILVNLLGNAVKFT-ETGGIRLRVKRHEQQ------LCFTVEDTG 553
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 417 PGIEPENLKLIFDPFFTTKDVGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:PRK15347 554 CGIDIQQQQQIFTPFYQADTHSQGTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLP 613
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
248-483 |
1.06e-19 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 92.41 E-value: 1.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 248 QLVQSEKLAALGT--------LLSGVAHELNNPLSNISTSAQILGEEIA-EGDLEFKKSliAQIEGQSDKARDIVRSLLE 318
Cdd:PRK10490 646 TLTASEEQARLASereqlrnaLLAALSHDLRTPLTVLFGQAEILTLDLAsEGSPHARQA--SEIRQQVLNTTRLVNNLLD 723
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 319 FSRIR----EVRKERLLLARLLAETVLLIRGQVpSKVDIAIDIPDDLEIV-ADKQRIQQVFLNLIKNAVDVVGDKGHIWV 393
Cdd:PRK10490 724 MARIQsggfNLRKEWLTLEEVVGSALQMLEPGL-SGHPINLSLPEPLTLIhVDGPLFERVLINLLENAVKYAGAQAEIGI 802
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 394 AARKIKETpdhkmeVEILIEDDGPGIEPENLKLIFDPFfttkdvGRGS--------GLGLFVVHNIIEWHGGTITVDSRP 465
Cdd:PRK10490 803 DAHVEGER------LQLDVWDNGPGIPPGQEQLIFDKF------ARGNkesaipgvGLGLAICRAIVEVHGGTIWAENRP 870
|
250
....*....|....*...
gi 1278273719 466 GLGTTFIIWLPggQEELP 483
Cdd:PRK10490 871 EGGACFRVTLP--LETPP 886
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
373-480 |
1.45e-19 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 90.29 E-value: 1.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 373 VFLNLIKNAVDVV----GDKGHIWVAARKIKEtpdhkmEVEILIEDDGPGIEPENLKLIFDPFFTTKDvGRGSGLGLFVV 448
Cdd:COG3290 285 ILGNLLDNAIEAVeklpEEERRVELSIRDDGD------ELVIEVEDSGPGIPEELLEKIFERGFSTKL-GEGRGLGLALV 357
|
90 100 110
....*....|....*....|....*....|..
gi 1278273719 449 HNIIEWHGGTITVDSRPGLGTTFIIWLPGGQE 480
Cdd:COG3290 358 KQIVEKYGGTIEVESEEGEGTVFTVRLPKEGE 389
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
177-476 |
2.01e-19 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 90.35 E-value: 2.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 177 FSTFALLALAIAITTILG-----RNVVRSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAFNRMLNELKlrqeQLVQ 251
Cdd:PRK09467 152 FSPLFRYTLAIGLLSVAGgwlfiRIQNRPLVALEHAALQVGKGEIPPPLREYGASEVRSVTRAFNQMAAGIK----QLED 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 252 SEKLaalgtLLSGVAHELNNPLSNISTSAQILGEEiaegDLEFKKSLIAQIEgqsdKARDIVRSLLEFsrIREVRKERLL 331
Cdd:PRK09467 228 DRTL-----LMAGVSHDLRTPLTRIRLATEMMSEE----DGYLAESINKDIE----ECNAIIEQFIDY--LRTGQEMPME 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 332 LARLLAETVLLIRGQVPSKVDIAIDIPDdLEIVADKQR--IQQVFLNLIKNAVDVvgdkGHIWVaarKIKETPDHKMeVE 409
Cdd:PRK09467 293 MADLNALLGEVIAAESGYEREIETALQP-GPIEVPMNPiaIKRALANLVVNAARY----GNGWI---KVSSGTEGKR-AW 363
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 410 ILIEDDGPGIEPENLKLIFDPfFTTKDVGR---GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:PRK09467 364 FQVEDDGPGIPPEQLKHLFQP-FTRGDSARgssGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLP 432
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
19-480 |
5.58e-19 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 89.31 E-value: 5.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 19 LIFMIGTALLTYGLVRRVERKVLFVEVIDDFFNATLEARRFEKNYFLYGQGKDLRENLFYWRKLDDLLRDNQEAFAAAVT 98
Cdd:COG2972 1 LSKSLSLLSIVLLLLILLLLVLLILLLSLLLIILLLLLLLILLLLLLILLLLLLLLLLLLLLLLLLLLLLLLLLLLLALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 99 TGGLANLREKVDGYHDSMLRLRQNTLAIPAELDGAEKSVLEERLRSMGKELTDLAEKT--SLTERRAIRTLLQATRNILI 176
Cdd:COG2972 81 LILLLLLLLLLLLILLLSLLLLLALILLLALLLLLSILLLILGLLLIILLLLSLLGWTlvSLIPKSELFRGLFSLRRLIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 177 FSTFALLALAIAITTILGRNVVRSLKILENYTRRISKGERKEADIKVHDqEIVSLLTAFNRM---LNELKLRQEQLVQSE 253
Cdd:COG2972 161 LIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLVRLEVSGND-EIGILARSFNEMverIKELIEEVYELELEK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 254 KLAALGTLLSGV-AHELNNPLSNISTSAQILGEEIAE------GDLeFKKSLiaQIEGQSDKARD---IVRSLLEFSRIR 323
Cdd:COG2972 240 KEAELKALQAQInPHFLFNTLNSIRWLAELEDPEEAEemlealSKL-LRYSL--SKGDELVTLEEeleLIKSYLEIQKLR 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 324 evrkerlllarllaetvllirgqVPSKVDIAIDIPDDLEIVADKQRIQQVFL-NLIKNAVDVVGDKGHIWVAARKIKETp 402
Cdd:COG2972 317 -----------------------FGDRLEVEIEIDEELLDLLIPKLILQPLVeNAIEHGIEPKEGGGTIRISIRKEGDR- 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 403 dhkmeVEILIEDDGPGIEPENLKLIFDPFfttKDVGRGSGLGLFVVHNIIEWH---GGTITVDSRPGLGTTFIIWLPGGQ 479
Cdd:COG2972 373 -----LVITVEDNGVGMPEEKLEKLLEEL---SSKGEGRGIGLRNVRERLKLYygeEYGLEIESEPGEGTTVTIRIPLEE 444
|
.
gi 1278273719 480 E 480
Cdd:COG2972 445 E 445
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
366-476 |
7.95e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 79.04 E-value: 7.95e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 366 DKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKikeTPDhkmEVEILIEDDGPGIEPENLKLIFDPFFTTKDVGR----GS 441
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQ---TPQ---EVRLDVEDSAPGVSDDQLARLFERFYRVESSRNrasgGS 74
|
90 100 110
....*....|....*....|....*....|....*
gi 1278273719 442 GLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16946 75 GLGLAICHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
372-476 |
2.38e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 77.61 E-value: 2.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 372 QVFLNLIKNAVDVV-GDKGHIWVAArkikeTPDHKMeVEILIEDDGPGIEPENLKLIFDPFFTTK----DVGRGSGLGLF 446
Cdd:cd16953 3 QVLRNLIGNAISFSpPDTGRITVSA-----MPTGKM-VTISVEDEGPGIPQEKLESIFDRFYTERpaneAFGQHSGLGLS 76
|
90 100 110
....*....|....*....|....*....|....
gi 1278273719 447 VVHNIIEWHGGTITVDSR--PGL--GTTFIIWLP 476
Cdd:cd16953 77 ISRQIIEAHGGISVAENHnqPGQviGARFTVQLP 110
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
376-476 |
1.90e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 74.63 E-value: 1.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 376 NLIKNAVDVVGDKGH----IWVAARkiketpDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDvGRGSGLGLFVVHNI 451
Cdd:cd16915 7 NLIDNALDALAATGApnkqVEVFLR------DEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKG-QGERGIGLALVRQS 79
|
90 100
....*....|....*....|....*
gi 1278273719 452 IEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16915 80 VERLGGSITVESEPGGGTTFSIRIP 104
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-476 |
2.17e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 74.67 E-value: 2.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGDKGHIWVAARKIKETPDHKMEVEilieDDGPGIEPENLKLIFDPF--FTTKDVGRGSGLGLFV 447
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPPRIEVGAEDVGEEWTFYVR----DNGIGIDPEYAEKVFGIFqrLHSREEYEGTGVGLAI 76
|
90 100
....*....|....*....|....*....
gi 1278273719 448 VHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16921 77 VRKIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
366-476 |
1.20e-15 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 72.91 E-value: 1.20e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 366 DKQRIQQVFLNLIKNAVDVVGDKGHIwvaaRKIKETPDHKmEVEILIEDDGPGIEPENLKLIFDPFFTTKDVG----RGS 441
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRI----RCILEKFRLN-RFLLTVSDSGPGIPPNLREEIFERFRQGDGSStrahGGT 75
|
90 100 110
....*....|....*....|....*....|....*
gi 1278273719 442 GLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16925 76 GLGLSIVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
102-476 |
3.12e-15 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 78.41 E-value: 3.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 102 LANLREKVDGYHDSMLRLRQNTlAIPAELDGAEKSVLEERLRsMGKELTDLAEKTSLTERRAIRTLLQATR----NILIF 177
Cdd:PRK11466 259 VATTLTTVSQYSDLLALYQQDS-EISNHLQTLAQNNIAQFAQ-FSSEVSQLVDTIELRNQHGLAHLEKASArgqySLLLL 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 178 STFALLALAIAITTILGRNVVRSLKILENYTRRISKGE-----RKEADIKVHDQeIVSLLTAFNRMLNELKLRQEQL--- 249
Cdd:PRK11466 337 GMVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDidspfPETAGVRELDT-IGRLMDAFRSNVHALNRHREQLaaq 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 250 --VQSEKLAAL------------------GTLLSGVAHELNNPLSNISTSAQILGEEIAegdLEFKKSLIAQIEGQSDKA 309
Cdd:PRK11466 416 vkARTAELQELviehrqaraeaekasqakSAFLAAMSHEIRTPLYGILGTAQLLADNPA---LNAQRDDLRAITDSGESL 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 310 RDIVRSLLEFSRIR------EVRKERLLLARLLAETVLLIRGQVPSK-VDIAIDIPDDLE--IVADKQRIQQVFLNLIKN 380
Cdd:PRK11466 493 LTILNDILDYSAIEaggknvSVSDEPFEPRPLLESTLQLMSGRVKGRpIRLATDIADDLPtaLMGDPRRIRQVITNLLSN 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 381 AVDVVgDKGHIWVAARkikeTPDHKMEVEIliEDDGPGIEPENLKLIFDPFFTTKDVGRGSGLGLFVVHNIIEWHGGTIT 460
Cdd:PRK11466 573 ALRFT-DEGSIVLRSR----TDGEQWLVEV--EDSGCGIDPAKLAEIFQPFVQVSGKRGGTGLGLTISSRLAQAMGGELS 645
|
410
....*....|....*.
gi 1278273719 461 VDSRPGLGTTFIIWLP 476
Cdd:PRK11466 646 ATSTPEVGSCFCLRLP 661
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
174-476 |
7.75e-15 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 76.60 E-value: 7.75e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 174 ILIFSTFallaLAIAITTILGRNVVRSLKILENYTRRISKGE---RKEADIKvhdQEIVSLLTAFNRMLNELKlRQEQLV 250
Cdd:PRK10549 169 IVALSTL----LAALATFLLARGLLAPVKRLVEGTHKLAAGDfttRVTPTSR---DELGRLAQDFNQLASTLE-KNEQMR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 251 QSeklaalgtLLSGVAHELNNPLSnistsaqILG---EEIAEGDLEFKKSLIAQIEGQSDKARDIVRSLLEFSRIRE--- 324
Cdd:PRK10549 241 RD--------FMADISHELRTPLA-------VLRgelEAIQDGVRKFTPESVASLQAEVGTLTKLVDDLHQLSLSDEgal 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 325 -VRKERLLLARLLAETVLLIRGQVPSK-VDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKiketp 402
Cdd:PRK10549 306 aYRKTPVDLVPLLEVAGGAFRERFASRgLTLQLSLPDSATVFGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQ----- 380
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1278273719 403 DHKMEVeILIEDDGPGIEPENLKLIFDPFFTTkDVGR-----GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:PRK10549 381 RDKTLR-LTFADSAPGVSDEQLQKLFERFYRT-EGSRnrasgGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELP 457
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
366-476 |
9.28e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 70.26 E-value: 9.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 366 DKQRIQQVFLNLIKNAVDVV----GDKGHIwvaarKIKETPDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDvgRGS 441
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIegrpSDVGEV-----RIRVEADQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRP--KGT 73
|
90 100 110
....*....|....*....|....*....|....*
gi 1278273719 442 GLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16944 74 GLGLAIVKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
376-481 |
1.13e-14 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 76.11 E-value: 1.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 376 NLIKNAVDVVG--DKGHIWVAARKiketpdHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKdvGRGSGLGLFVVHNIIE 453
Cdd:PRK11086 440 NLIENALEAVGgeEGGEISVSLHY------RNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTK--GSNRGVGLYLVKQSVE 511
|
90 100
....*....|....*....|....*...
gi 1278273719 454 WHGGTITVDSRPGLGTTFIIWLPGGQEE 481
Cdd:PRK11086 512 NLGGSIAVESEPGVGTQFFVQIPWDGER 539
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-476 |
2.38e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 66.20 E-value: 2.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVvgdkghiwvAARKIK--ETPDHKmEVEILIEDDGPGIEPENLKLIFDPFFTTKDV----GRGSGL 443
Cdd:cd16949 1 LARALENVLRNALRY---------SPSKILldISQDGD-QWTITITDDGPGVPEDQLEQIFLPFYRVDSArdreSGGTGL 70
|
90 100 110
....*....|....*....|....*....|...
gi 1278273719 444 GLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16949 71 GLAIAERAIEQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
181-476 |
2.47e-13 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 71.56 E-value: 2.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 181 ALLALAIAITTILG-RNVVRSLKILENYTRRISKGERKEadiKVHDQEIVSLL---TAFNRMLNELklrqEQLVQSEKla 256
Cdd:PRK10604 143 ALIGLSLAFPVFLWmRPHWQDMLKLEAAAQRLGDGHLAE---RIHFDEGSSLErlgVAFNQMADNI----NALIASKK-- 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 257 algTLLSGVAHELNNPL----------SNISTS-AQILGEEIaeGDLEfkksliAQIEGQSDKAR------DIVRSLLEF 319
Cdd:PRK10604 214 ---QLIDGIAHELRTPLvrlryrlemsDNLSAAeSQALNRDI--GQLE------ALIEELLTYARldrpqnELHLSEPDL 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 320 -----SRIREVRkerlllarllaetvllirgQVPSKVDIAIDIPDD-LEIVADKQRIQQVFLNLIKNAVDVVGDK--GHI 391
Cdd:PRK10604 283 pawlsTHLADIQ-------------------AVTPEKTVRLDTPHQgDYGALDMRLMERVLDNLLNNALRYAHSRvrVSL 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 392 WVaarkiketpdHKMEVEILIEDDGPGIEPENLKLIFDPFfTTKDVGR-----GSGLGLFVVHNIIEWHGGTITVDSRPG 466
Cdd:PRK10604 344 LL----------DGNQACLIVEDDGPGIPPEERERVFEPF-VRLDPSRdratgGCGLGLAIVHSIALAMGGSVNCDESEL 412
|
330
....*....|
gi 1278273719 467 LGTTFIIWLP 476
Cdd:PRK10604 413 GGARFSFSWP 422
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-476 |
4.58e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 65.16 E-value: 4.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVvgdkGHIWVAARKIKETPDHKMEVEilieDDGPGIEPENLKLIFDPFfTTKDVGR---GSGLGLF 446
Cdd:cd16950 1 LKRVLSNLVDNALRY----GGGWVEVSSDGEGNRTRIQVL----DNGPGIAPEEVDELFQPF-YRGDNARgtsGTGLGLA 71
|
90 100 110
....*....|....*....|....*....|
gi 1278273719 447 VVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16950 72 IVQRISDAHGGSLTLANRAGGGLCARIELP 101
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
239-476 |
8.36e-13 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 70.32 E-value: 8.36e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 239 LNELKLRQEQ---------LVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFKKSLIAQIEGQSDKA 309
Cdd:TIGR02938 248 ISNLREEQERarlsalqalMAEEERLEAIRETLSAAIHRLQGPMNLISAAISVLQRRGDDAGNPASAAMLQQALSAGREH 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 310 RDIVRSLLEFSRIREVRKERLLLARLLAETV----LLIRGQVpskVDI--AIDIPddlEIVADKQRIQQVFLNLIKNAVD 383
Cdd:TIGR02938 328 MEALRQVIPQSPQEIVVPVNLNQILRDVITLstprLLAAGIV---VDWqpAATLP---AILGRELQLRSLFKALVDNAIE 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 384 VVGDKGHIWVAARKIKETPDHKMEVEIliEDDGPGIEPENLKLIFDPFFTTK-DVGRGSGLGLFVVHNIIEWHGGTITVD 462
Cdd:TIGR02938 402 AMNIKGWKRRELSITTALNGDLIVVSI--LDSGPGIPQDLRYKVFEPFFTTKgGSRKHIGMGLSVAQEIVADHGGIIDLD 479
|
250
....*....|....
gi 1278273719 463 SRPGLGTTFIIWLP 476
Cdd:TIGR02938 480 DDYSEGCRIIVEFR 493
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-475 |
1.87e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 64.07 E-value: 1.87e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 352 DIAIDIPD-DLEIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARkiketpDHKMEVEILIEDDGPGIEPENLKLIFDP 430
Cdd:cd16947 2 QVEINIPDrPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLR------EDEKHVYIDIWDKGKGISETEKDHVFER 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1278273719 431 FFTTKDVG----RGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWL 475
Cdd:cd16947 76 LYTLEDSRnsakQGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
362-476 |
6.44e-12 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 64.14 E-value: 6.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 362 EIVADKQRIQQV---FLNLIKNAVD----VVGD--------KGHIWVAARKiketpdHKMEVEILIEDDGPGIEPENLK- 425
Cdd:cd16916 28 DTELDKSVLEKLadpLTHLLRNAVDhgieAPEErlaagkppEGTITLRAEH------QGNQVVIEVSDDGRGIDREKIRe 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1278273719 426 -----------------------LIFDPFFTTKDV-----GRGsgLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16916 102 kaierglitadeaatlsddevlnLIFAPGFSTAEQvtdvsGRG--VGMDVVKRSIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
410-476 |
1.04e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 61.29 E-value: 1.04e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278273719 410 ILIEDDGPGIEPENLKLIFDPFFTTkDVGR-----GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16939 33 LIVEDDGPGIPAAARERVFEPFVRL-DPSRdratgGFGLGLAIVHRVALWHGGHVECDDSELGGACFRLTWP 103
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
265-476 |
1.29e-11 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 66.19 E-value: 1.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 265 VAHELNNPLSNISTSAQILGEEIAEGDLEfKKSLIAQIEgQSDKARDIVRSLLEFSRIrEVRKERLLLARLLAETVLLI- 343
Cdd:PRK11006 211 VSHELRTPLTVLQGYLEMMQDQPLEGALR-EKALHTMRE-QTQRMEGLVKQLLTLSKI-EAAPTIDLNEKVDVPMMLRVl 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 344 --RGQVPS--KVDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKIketpDHKMEVEIliEDDGPGI 419
Cdd:PRK11006 288 erEAQTLSqgKHTITFEVDNSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRV----PQGAEFSV--EDNGPGI 361
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278273719 420 EPENLKLIFDPFFT-----TKDVGrGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:PRK11006 362 APEHIPRLTERFYRvdkarSRQTG-GSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
376-475 |
7.38e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 59.34 E-value: 7.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 376 NLIKNAVDVVGDKGHIWVaarkIKETPDHKMeveILIEDDGPGIEPENLKLIFDPFF-TTKDVGRGSGLGLFVVHNIIEW 454
Cdd:cd16940 20 NLVDNAVRYSPQGSRVEI----KLSADDGAV---IRVEDNGPGIDEEELEALFERFYrSDGQNYGGSGLGLSIVKRIVEL 92
|
90 100
....*....|....*....|.
gi 1278273719 455 HGGTITVDSRPGLGTTFIIWL 475
Cdd:cd16940 93 HGGQIFLGNAQGGGLEAWVRL 113
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
350-476 |
8.61e-11 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 64.19 E-value: 8.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 350 KVDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVDVVgDKGHIWVaaRKIKETPDH-KMEVEilieDDGPGIEPENLKLIF 428
Cdd:PRK11091 379 RFDLEPLLPLPHKVITDGTRLRQILWNLISNAVKFT-QQGGVTV--RVRYEEGDMlTFEVE----DSGIGIPEDELDKIF 451
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1278273719 429 DPFFTTKDV--GR---GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:PRK11091 452 AMYYQVKDShgGKpatGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIH 504
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
353-476 |
1.16e-10 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 64.22 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 353 IAIDIPDDLEivADKQRIQQVFLNLIKNAVDVVgDKGHIWVAARKiketpdHKMEVEILIEDDGPGIEPENLKLIFDPFF 432
Cdd:PRK10841 548 IEPDVPVALN--GDPMRLQQVISNLLSNAIKFT-DTGCIVLHVRV------DGDYLSFRVRDTGVGIPAKEVVRLFDPFF 618
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1278273719 433 ttkDVG-------RGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:PRK10841 619 ---QVGtgvqrnfQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIP 666
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
351-471 |
1.40e-10 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 63.71 E-value: 1.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 351 VDIAIDIPDDLeiVADKQRIQQVFLNLIKNAVDVVgDKG--HIWVAARKIKetpDHKMEVEILIEDDGPGIEPENLKLIF 428
Cdd:PRK11107 392 LNIDPDVPDNV--IGDPLRLQQIITNLVGNAIKFT-ESGniDILVELRALS---NTKVQLEVQIRDTGIGISERQQSQLF 465
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1278273719 429 DPFfTTKD--VGR---GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTF 471
Cdd:PRK11107 466 QAF-RQADasISRrhgGTGLGLVITQKLVNEMGGDISFHSQPNRGSTF 512
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
407-476 |
1.99e-10 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 62.89 E-value: 1.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 407 EVEILIEDDGPGIEPENLK------------------------LIFDPFFTTKDV-----GRGsgLGLFVVHNIIEWHGG 457
Cdd:COG0643 321 RVVIEVSDDGRGLDLEKIRakaiekglitaeeaaalsdeelleLIFAPGFSTAEEvtdlsGRG--VGMDVVKTNIEALGG 398
|
90
....*....|....*....
gi 1278273719 458 TITVDSRPGLGTTFIIWLP 476
Cdd:COG0643 399 TIEIESEPGKGTTFTLRLP 417
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
407-476 |
2.83e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 57.30 E-value: 2.83e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1278273719 407 EVEILIEDDGPGIEPENLKLIFDPFFTTKdVGR----GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16948 37 GVVLSIKDFGIGIPEEDLPRVFDKGFTGE-NGRnfqeSTGMGLYLVKKLCDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
366-474 |
3.26e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 57.09 E-value: 3.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 366 DKQRIQQVFLNLIKNAVDVVGDKGHIWVAArkiketpdhKMEVEIL---IEDDGPGIEPENLKLIFDPFFTTK---DVGR 439
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISI---------YDEEEYLyfeIWDNGHGFSEQDLKKALELFYRDDtsrRSGG 71
|
90 100 110
....*....|....*....|....*....|....*
gi 1278273719 440 GSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIW 474
Cdd:cd16975 72 HYGMGLYIAKNLVEKHGGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-475 |
6.79e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 56.31 E-value: 6.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGDKGHIWVAARKIKEtpdhkmEVEILIEDDGPGIEPENLKLIFDPFFT---TKDVGRGSGLGLF 446
Cdd:cd16945 5 LRQAINNLLDNAIDFSPEGGLIALQLEADTE------GIELLVFDEGSGIPDYALNRVFERFYSlprPHSGQKSTGLGLA 78
|
90 100
....*....|....*....|....*....
gi 1278273719 447 VVHNIIEWHGGTITVDSRPGlGTTFIIWL 475
Cdd:cd16945 79 FVQEVAQLHGGRITLRNRPD-GVLAFLTL 106
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
174-476 |
9.97e-10 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 60.33 E-value: 9.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 174 ILIFSTFALLALAIAITtilgrnvvRSLKILENYTRRISKGE-RKEADIKVHDQEIVSLLTAFNRM---LNELKLRQEQL 249
Cdd:PRK09470 175 TMLVSTPLLLWLAWSLA--------KPARKLKNAADEVAQGNlRQHPELETGPQEFRQAGASFNQMvtaLERMMTSQQRL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 250 vqseklaalgtlLSGVAHELNNPLSNISTSAQILGEEIAEGdlefkkSLIAQIEGQSDKARDIVRSLLEFSRI------- 322
Cdd:PRK09470 247 ------------LSDISHELRTPLTRLQLATALLRRRQGES------KELERIETEAQRLDSMINDLLVLSRNqqknhle 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 323 REVRKERlllarllaetvllirgqvpskvDIAIDIPDD-----------LEIVADKQR---------IQQVFLNLIKNAV 382
Cdd:PRK09470 309 RETFKAN----------------------SLWSEVLEDakfeaeqmgksLTVSAPPGPwpingnpnaLASALENIVRNAL 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 383 DVvgDKGHIWVAarkikeTPDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTkDVGR-----GSGLGLFVVHNIIEWHGG 457
Cdd:PRK09470 367 RY--SHTKIEVA------FSVDKDGLTITVDDDGPGVPEEEREQIFRPFYRV-DEARdresgGTGLGLAIVENAIQQHRG 437
|
330
....*....|....*....
gi 1278273719 458 TITVDSRPGLGTTFIIWLP 476
Cdd:PRK09470 438 WVKAEDSPLGGLRLTIWLP 456
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
232-476 |
1.01e-09 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 61.29 E-value: 1.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 232 LTAFNRMLNELKLRQEQLVQSEklAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFKKSLIAQIEGQSdkARD 311
Cdd:PRK09959 688 ITETRDLIHALEVERNKAINAT--VAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQS--LLG 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 312 IVRSLLEFSRIR----EVRKERLLLARLLAETVLLIrGQVPSKVDIAID----IPDDLEIVADKQRIQQVFLNLIKNAVD 383
Cdd:PRK09959 764 LIGEILDVDKIEsgnyQLQPQWVDIPTLVQNTCHSF-GAIAASKSIALScsstFPDHYLVKIDPQAFKQVLSNLLSNALK 842
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 384 VVGDkGHIWVAARKIKETPDHKMeVEILIEDDGPGIEPENLKLIFDPFFTTKdVGR---GSGLGLFVVHNIIEWHGGTIT 460
Cdd:PRK09959 843 FTTE-GAVKITTSLGHIDDNHAV-IKMTIMDSGSGLSQEEQQQLFKRYSQTS-AGRqqtGSGLGLMICKELIKNMQGDLS 919
|
250
....*....|....*.
gi 1278273719 461 VDSRPGLGTTFIIWLP 476
Cdd:PRK09959 920 LESHPGIGTTFTITIP 935
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
351-473 |
1.10e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 56.49 E-value: 1.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 351 VDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVdvvgdK---GHIWVAARKikeTPDHkmeVEILIEDDGPGIEPENLKLI 427
Cdd:cd16954 19 VSISLDISPELRFPGERNDLMELLGNLLDNAC-----KwclEFVEVTARQ---TDGG---LHLIVDDDGPGVPESQRSKI 87
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1278273719 428 FDPFFTTKDVGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFII 473
Cdd:cd16954 88 FQRGQRLDEQRPGQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEV 133
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-479 |
1.40e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 55.29 E-value: 1.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGDKGHIWVAARKIKETpdhkmeVEILIEDDGPGIEPENLKLIFDPFFTTkDVGR-----GSGLG 444
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESG------ARLSVEDTGPGIPPEHIPRLTERFYRV-DIERcrntgGTGLG 73
|
90 100 110
....*....|....*....|....*....|....*
gi 1278273719 445 LFVVHNIIEWHGGTITVDSRPGLGTTFIIWLPGGQ 479
Cdd:cd16952 74 LAIVKHVMSRHDARLLIASELGKGSRFTCLFPSSR 108
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
257-324 |
3.76e-09 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 52.98 E-value: 3.76e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278273719 257 ALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLefkKSLIAQIEGQSDKARDIVRSLLEFSRIRE 324
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQ---REYLETILRSAERLLRLINDLLDLSRIEA 65
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
255-321 |
4.25e-09 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 52.60 E-value: 4.25e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278273719 255 LAALGTLLSGVAHELNNPLSNISTSAQILGEEIaeGDLEFKKSLIAQIEGQSDKARDIVRSLLEFSR 321
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEEL--LDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
257-324 |
1.93e-08 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 50.64 E-value: 1.93e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278273719 257 ALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDlefKKSLIAQIEGQSDKARDIVRSLLEFSRIRE 324
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEE---QREYLETILREAERLLRLINDLLDLSRIEA 65
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
366-476 |
8.51e-08 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 54.39 E-value: 8.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 366 DKQRIQQVFLNLIKNAVDVVGDKGHIWVaarKIKETPDhkmEVEILIEDDGPGIEPENLKLIFDPFF----TTKDVGRGS 441
Cdd:PRK09835 372 DPLMLRRAISNLLSNALRYTPAGEAITV---RCQEVDH---QVQLVVENPGTPIAPEHLPRLFDRFYrvdpSRQRKGEGS 445
|
90 100 110
....*....|....*....|....*....|....*
gi 1278273719 442 GLGLFVVHNIIEWHGGTITVDSRPgLGTTFIIWLP 476
Cdd:PRK09835 446 GIGLAIVKSIVVAHKGTVAVTSDA-RGTRFVISLP 479
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
161-476 |
4.77e-07 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 51.89 E-value: 4.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 161 RRAIRTLLQATrniLIFSTFALLALAIAITTIlgrnvVRSLKILENytrrisKGERKEAD----IKVHD--QEIVSLLTA 234
Cdd:PRK10755 57 REAVASLLVPS---LVMVSLTLLICFQAVRWI-----TRPLAELQK------ELEARTADnltpIAIHSstLEIEAVTSA 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 235 FNRMLNELK--LRQEQLVQSEklaalgtllsgVAHELNNPLSNISTSAQILGEE-IAEGdlefkKSLIAQIegqsDKARD 311
Cdd:PRK10755 123 LNQLVSRLTstLDQERLFTAD-----------VAHELRTPLAGIRLHLELLEKQhHIDV-----APLIARL----DQMMH 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 312 IVRSLLEFSRIR-----------EVRKERLLLARLLAETVLLIRGQ---VPskvdiaiDIPDDLEIVADKQRIQQVFLNL 377
Cdd:PRK10755 183 TVEQLLQLARAGqsfssghyqtvKLLEDVILPSQDELSEMLEQRQQtllLP-------ESAADITVQGDATLLRLLLRNL 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 378 IKNAVDVVGDKGHIWVaarKIKETPDHkmeVEILIEDDGPGIEPENLKLIFDPFFTTKDVGRGSGLGLFVVHNIIEWHGG 457
Cdd:PRK10755 256 VENAHRYSPEGSTITI---KLSQEDGG---AVLAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQLHHG 329
|
330 340
....*....|....*....|
gi 1278273719 458 TITVDSRP-GLGTTFIIWLP 476
Cdd:PRK10755 330 QFFLQNRQeRSGTRAWVWLP 349
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
371-476 |
5.96e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 47.77 E-value: 5.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 371 QQVFLNLIKNAVDVVGDKGHIWVAARKIKETpdhkmeVEILIEDDGPGIEPENLKLIFDPFFTTkDVGR---GSGLGLFV 447
Cdd:cd16923 2 QRVFSNLLSNAIKYSPENTRIYITSFLTDDV------VNIMFKNPSSHPLDFKLEKLFERFYRG-DNSRnteGAGLGLSI 74
|
90 100
....*....|....*....|....*....
gi 1278273719 448 VHNIIEWHGGTITVDSRpGLGTTFIIWLP 476
Cdd:cd16923 75 AKAIIELHGGSASAEYD-DNHDLFKVRLP 102
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
351-468 |
7.34e-07 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 51.56 E-value: 7.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 351 VDIAIDIPDDLEIVADKQRIQQVFLNLIKNA-------VDVvgdkghiwvAARkikETPDHkmeVEILIEDDGPGIEPEN 423
Cdd:PRK10815 360 VNITLDISPEITFVGEKNDFMEVMGNVLDNAckyclefVEI---------SAR---QTDEH---LHIVVEDDGPGIPESK 424
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1278273719 424 LKLIFDPFFTTKDVGRGSGLGLFVVHNIIEWHGGTITVDSRPgLG 468
Cdd:PRK10815 425 RELIFDRGQRADTLRPGQGLGLSVAREITEQYEGKISAGDSP-LG 468
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
180-468 |
1.11e-06 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 50.80 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 180 FALLALAIAITTILGRNVvRSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAfnrmLNELKLRQEQLVQSEKlaalg 259
Cdd:PRK10337 169 VALPIMLIILMVLLGREL-APLKKLALALRMRDPDSETPLNATGVPSEVRPLVEA----LNQLFARTHAMMVRER----- 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 260 TLLSGVAHELNNPLSNISTSAQILgeEIAEGDLEFKKSLIAQIEGQSDKARDIVRSLLEFSRI------REVRKERLLLA 333
Cdd:PRK10337 239 RFTSDAAHELRSPLAALKVQTEVA--QLSDDDPQARKKALLQLHAGIDRATRLVDQLLTLSRLdsldnlQDVAEIPLEDL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 334 RLLAETVLLIRGQvPSKVDIAIDIPDDLEIvadkQRIQQVFL-----NLIKNAVDVV--GDKGHIWVAARKIKetpdhkm 406
Cdd:PRK10337 317 LQSAVMDIYHTAQ-QAGIDVRLTLNAHPVI----RTGQPLLLsllvrNLLDNAIRYSpqGSVVDVTLNARNFT------- 384
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1278273719 407 eveilIEDDGPGIEPENLKLIFDPFFttKDVGR---GSGLGLFVVHNIIEWHGGTITVDSRPGLG 468
Cdd:PRK10337 385 -----VRDNGPGVTPEALARIGERFY--RPPGQeatGSGLGLSIVRRIAKLHGMNVSFGNAPEGG 442
|
|
| HATPase_YpdA-like |
cd16955 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-476 |
1.35e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli YpdA, a HK of the two-component system (TCS) YpdA-YpdB which is involved in a nutrient sensing regulatory network with YehU-YehT. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and some have a GAF sensor domain; some contain a DUF3816 domain; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340431 [Multi-domain] Cd Length: 102 Bit Score: 46.68 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGDKGHIWVAARKIKETpdhkmEVEILIEDDGPGIEPENLKLIF-DPFFTTKdvgrgsgLGLFVV 448
Cdd:cd16955 6 IQPLVENAIVHGIQEKKGKGVVKISVKKQLKN-----RLHIAVEDNGIGISPKVIERVEqDEMPGNK-------IGLLNV 73
|
90 100
....*....|....*....|....*....
gi 1278273719 449 HN-IIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:cd16955 74 HQrLKLGYGEGLHIRSRPDPGTLIAFYIP 102
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
407-476 |
4.58e-06 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 48.08 E-value: 4.58e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 407 EVEILIEDDGPGIEPEnlklifdpffttkdVGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:COG4585 193 ELTLTVRDDGVGFDPE--------------AAPGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLP 248
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
17-315 |
5.61e-06 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 48.86 E-value: 5.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 17 LLLIFMIGTALLTYGLVRRVERKVLFVEVIDDFFNATLEARRFEKNYFLYGQGKDLRENLFYWRKLDDLLRDNQEAFAAA 96
Cdd:COG0840 28 ALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 97 VTTGGLANLREKVDGYHDSMLRLRQNTLAIPAELDGAEKSVLEERLRsmGKELTDLAEKTSLTERRAIRTLLQATRNILI 176
Cdd:COG0840 108 ALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLA--AAAAAAAALAALLEAAALALAAAALALALLA 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 177 FSTFALLALAIAITTILGRNVVRSLKILENYTRRISKGE-RKEADIKVHDqEIVSLLTAFNRMLNELK-----LRQ--EQ 248
Cdd:COG0840 186 AALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDlTVRIDVDSKD-EIGQLADAFNRMIENLRelvgqVREsaEQ 264
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278273719 249 LVQ-SEKLAALGTLLSGVAHELNNPLSNISTSAqilgEEIAEGdlefkkslIAQIEGQSDKARDIVRS 315
Cdd:COG0840 265 VASaSEELAASAEELAAGAEEQAASLEETAAAM----EELSAT--------VQEVAENAQQAAELAEE 320
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
157-473 |
2.05e-05 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 46.80 E-value: 2.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 157 SLTERRAIRTLLQATRNILIFSTFALLALAIAITTILGRNVVRSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAFN 236
Cdd:COG3850 102 LLLLLLLLLLAAAINRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFN 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 237 RMLNELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFKKSLIAQIEGQSDKARDIVRSL 316
Cdd:COG3850 182 RMADELQELYAELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAG 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 317 LEFSRIREVRKERLLLARLLAETVLLIRGQVPSKVDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAAR 396
Cdd:COG3850 262 LLELLLALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALL 341
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278273719 397 KIKETPDHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDVGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFII 473
Cdd:COG3850 342 ELASILALQAALEAAAAGAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGAAGQGAGLVDVEGGVAGEGGLVV 418
|
|
| CHASE3 |
COG5278 |
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms]; |
4-378 |
1.11e-03 |
|
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 41.43 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 4 SFSIRQKITYGFSLLLIFMIGTALLTYGLVRRVERKVLFVEV-------IDDFFNATLEARRFEKNYFLYGQGKDL---- 72
Cdd:COG5278 3 NLSIRRKLLLGFALALLLLLVLGVLSYLSLNRLREASEWVEHtyevlraLEELLSALLDAETGQRGYLLTGDESFLepye 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 73 ---RENLFYWRKLDDLLRDNQEAFAAavttggLANLREKVDGYHDSMLRLrqntlaIPAELDGAEKSVLEERLRSMGKEL 149
Cdd:COG5278 83 earAEIDELLAELRSLTADNPEQQAR------LDELEALIDQWLAELEQV------IALRRAGGLEAALALVRSGEGKAL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 150 TDLAEKTSLTERRAIRTLLQATRNILIFSTFALLALAIAITTILGRNVVRSLKILENYTRRISKGERKEADIKVHDQEIV 229
Cdd:COG5278 151 MDEIRARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 230 SLLTAFNRMLNELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFKKSLIAQIEGQSDKA 309
Cdd:COG5278 231 ALELLAALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAA 310
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1278273719 310 RDIVRSLLEFSRIREVRKERLLLARLLAETVLLIRGQVPSKVDIAIDIPDDLEIVADKQRIQQVFLNLI 378
Cdd:COG5278 311 AAAAAAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEV 379
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
402-483 |
1.41e-03 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 41.46 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 402 PDHKMEVEILIEDDGPGIEPENLKLIFDPFF--TTKD-VGRGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLPGG 478
Cdd:PRK10618 594 ESSPDRLTIRILDTGAGVSIKELDNLHFPFLnqTQGDrYGKASGLTFFLCNQLCRKLGGHLTIKSREGLGTRYSIHLKML 673
|
....*
gi 1278273719 479 QEELP 483
Cdd:PRK10618 674 AADPE 678
|
|
| HATPase_YpdA-YehU-LytS-like |
cd16924 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-476 |
1.65e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA, YehU, Bacillus subtilis LytS, and some hybrid sensor histidine kinases; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. It also includes the HATPase domains of Escherichia coli YpdA and YehU, HKs of YpdA-YpdB and YehU-YehTCSs, which are involved together in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), some having accessory sensor domain(s) such as Cache, HAMP or GAF; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340401 [Multi-domain] Cd Length: 103 Bit Score: 37.81 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 370 IQQVFLNLIKNAVDVVGDKGHIWVAARKIKETpdhkmeVEILIEDDGPGIEPENLKLIfdpfftTKDVGRGSGLGLFVVH 449
Cdd:cd16924 6 LQPLVENAIQHGLSPLTDKGVVTISALKEDNH------VMIEVEDNGRGIDPKVLNIL------GKKPKEGNGIGLYNVH 73
|
90 100 110
....*....|....*....|....*....|
gi 1278273719 450 N-IIEWHGG--TITVDSRPGLGTTFIIWLP 476
Cdd:cd16924 74 QrLILLFGEdyGIHIASEPDKGTRITFTIP 103
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
1-416 |
1.66e-03 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 40.87 E-value: 1.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 1 MRLSFSIRQKITYGFSLLLIFMIGTALLTYGLVRRVERKVLFVEVIDDFFNATLEARRFEKNYFLYGQGKDLRENLFYWR 80
Cdd:COG2770 40 LLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALA 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 81 KLDDLLRDNQEAFAAAVTTGGLANLREKVDGYHDSMLRLRQNTLAIPAELDGAEKSVLEERLRSMGKELTDLAEKTSLTE 160
Cdd:COG2770 120 LLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLL 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 161 RRAIRTLLQATRNILIFSTFALLALAIAITTILGRNVVRSLKILENYTRRISKGERKEADIKVHDQEIVSLLTAFNRMLN 240
Cdd:COG2770 200 LVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMAD 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 241 ELKLRQEQLVQSEKLAALGTLLSGVAHELNNPLSNISTSAQILGEEIAEGDLEFKKSLIAQIEGQSDKARDIVRSLLEFS 320
Cdd:COG2770 280 SLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAAL 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 321 RIREVRKERLLLARLLAETVLLIRGQVPSKVDIAIDIPDDLEIVADKQRIQQVFLNLIKNAVDVVGDKGHIWVAARKIKE 400
Cdd:COG2770 360 LLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALE 439
|
410
....*....|....*.
gi 1278273719 401 TPDHKMEVEILIEDDG 416
Cdd:COG2770 440 LAAAAIAAAAAAEAEG 455
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
389-476 |
1.72e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 37.53 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 389 GHIWVaarKIKETPDhkmEVEILIEDDGPGIEPEnlklifdpffttkDVGRGSGLGLFVVHNIIEWHGGTITVDSRPGLG 468
Cdd:cd16917 19 SRVRV---TLSYTAD---ELTLTVVDDGVGFDGP-------------APPGGGGFGLLGMRERAELLGGTLTIGSRPGGG 79
|
....*...
gi 1278273719 469 TTFIIWLP 476
Cdd:cd16917 80 TRVTARLP 87
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
403-476 |
2.14e-03 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 40.59 E-value: 2.14e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1278273719 403 DHKMEVEILIEDDGPGIEPENLKLIFDPFFTTKDVGRGS-GLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:PRK15053 464 DEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEhGIGLYLIASYVTRCGGVITLEDNDPCGTLFSIFIP 538
|
|
| PRK10547 |
PRK10547 |
chemotaxis protein CheA; Provisional |
426-476 |
2.77e-03 |
|
chemotaxis protein CheA; Provisional
Pssm-ID: 236712 [Multi-domain] Cd Length: 670 Bit Score: 40.10 E-value: 2.77e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1278273719 426 LIFDPFFTT----KDVGrGSGLGLFVVHNIIEWHGGTITVDSRPGLGTTFIIWLP 476
Cdd:PRK10547 469 LIFAPGFSTaeqvTDVS-GRGVGMDVVKRNIQEMGGHVEIQSKQGKGTTIRILLP 522
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
407-475 |
4.27e-03 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 37.20 E-value: 4.27e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1278273719 407 EVEILIEDDGPGIEPENLKlifDPFfttkDVGRGSGLGLFVVHNIIEwhggTITVDSRPGlGTT--FIIWL 475
Cdd:COG2172 69 GLEIEVRDEGPGFDPEDLP---DPY----STLAEGGRGLFLIRRLMD----EVEYESDPG-GTTvrLVKRL 127
|
|
| HAMP |
pfam00672 |
HAMP domain; |
192-243 |
4.48e-03 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 35.29 E-value: 4.48e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1278273719 192 ILGRNVVRSLKILENYTRRISKGE-RKEADIKVHDqEIVSLLTAFNRMLNELK 243
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDlDVRLPVSGRD-EIGELARAFNQMAERLR 52
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
386-476 |
4.68e-03 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 39.50 E-value: 4.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278273719 386 GDKGHIWVAARKIKETpdhkmeVEILIEDDGPGIePENLklifdpffttkDVGRGSGLGLFVVHNIIEWHGGTITVDSRP 465
Cdd:COG3920 419 GEGGRIRVSWRREDGR------LRLTVSDNGVGL-PEDV-----------DPPARKGLGLRLIRALVRQLGGTLELDRPE 480
|
90
....*....|.
gi 1278273719 466 glGTTFIIWLP 476
Cdd:COG3920 481 --GTRVRITFP 489
|
|
| HATPase_SpoIIAB-like |
cd16942 |
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein ... |
407-473 |
6.79e-03 |
|
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of SpoIIAB, an anti sigma-F factor and a serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli where, early in sporulation, the cell divides into two unequal compartments: a larger mother cell and a smaller forespore. Sigma-F transcription factor is activated in the forespore directly after the asymmetric septum forms, and its spatial and temporal activation is required for sporulation. Free sigma-F can associate with the RNA polymerase core and activate transcription of the sigma-F regulon, its regulation may comprise a partner-switching mechanism involving SpoIIAB, SpoIIAA, and sigma-F as follows: SpoIIAB can form alternative complexes with either: i) sigma-F, holding it in an inactive form and preventing its association with RNA polymerase, or ii) unphosphorylated SpoIIAA and a nucleotide, either ATP or ADP. In the presence of ATP, SpoIIAB acts as a kinase to specifically phosphorylate a serine residue of SpoIIAA; this phosphorylated form has low affinity for SpoIIAB and dissociates, making SpoIIAB available to capture sigma-F. SpoIIAA may then be dephosphorylated by a SpoIIE serine phosphatase and be free to attack the SpoIIAB sigma-F complex to induce the release of sigma-F.
Pssm-ID: 340418 [Multi-domain] Cd Length: 135 Bit Score: 36.75 E-value: 6.79e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278273719 407 EVEILIEDDGPGIEpeNLKLIFDPFFTTKDVGRGSGLGLFVVHNIIEwhggTITVDSRPGLGTTFII 473
Cdd:cd16942 73 VVHLTVRDEGVGIP--DIEEARQPLFTTKPELERSGMGFTIMENFMD----EVIVESEVNKGTTVYL 133
|
|
| |
