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Conserved domains on  [gi|1278550848|gb|PJA67011|]
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MAG: DNA methyltransferase, partial [Piscirickettsiaceae bacterium CG_4_9_14_3_um_filter_43_564]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Type_ISP_C super family cl40280
Type ISP C-terminal specificity domain; This is the C-terminal domain of Type ISP ...
 1-119 2.28e-27

Type ISP C-terminal specificity domain; This is the C-terminal domain of Type ISP restriction-modification enzyme LLaBIII present in Lactococcus lactis subsp. cremoris. Type ISP restriction-modification (RM) enzymes provide a potent defence against infection by foreign and bacteriophage DNA. This domain interacts extensively with DNA and is known as the target recognition domain (TRD). TRD works by recognising 6/7 base pairs of asymmetric sequence.


The actual alignment was detected with superfamily member pfam18135:

Pssm-ID: 465663  Cd Length: 342  Bit Score: 103.10  E-value: 2.28e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278550848   1 WPLVSLGGQIRQLHLM-ES-PALDQAITPYPVAGSNVVsrkiskTSPGYEAIDDThGKVWINDNQYFDQVPLLAWEFYIG 78
Cdd:pfam18135 229 WELVELGRELADLHLNyERvAPLPPGITTYPPDGDYRV------EKMKYDKKKDK-GTIIINGEGTFTGVPPEAWEYVVG 301

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1278550848  79 GYqPAQKWLKDRQDRELSFDD-IMHYQKIIVALVETDRFMKE 119
Cdd:pfam18135 302 GK-SALEWLKDRYGVKLDKDSgILNDPNDWAKLDETEEILDL 342
 
Name Accession Description Interval E-value
Type_ISP_C pfam18135
Type ISP C-terminal specificity domain; This is the C-terminal domain of Type ISP ...
 1-119 2.28e-27

Type ISP C-terminal specificity domain; This is the C-terminal domain of Type ISP restriction-modification enzyme LLaBIII present in Lactococcus lactis subsp. cremoris. Type ISP restriction-modification (RM) enzymes provide a potent defence against infection by foreign and bacteriophage DNA. This domain interacts extensively with DNA and is known as the target recognition domain (TRD). TRD works by recognising 6/7 base pairs of asymmetric sequence.


Pssm-ID: 465663  Cd Length: 342  Bit Score: 103.10  E-value: 2.28e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278550848   1 WPLVSLGGQIRQLHLM-ES-PALDQAITPYPVAGSNVVsrkiskTSPGYEAIDDThGKVWINDNQYFDQVPLLAWEFYIG 78
Cdd:pfam18135 229 WELVELGRELADLHLNyERvAPLPPGITTYPPDGDYRV------EKMKYDKKKDK-GTIIINGEGTFTGVPPEAWEYVVG 301

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1278550848  79 GYqPAQKWLKDRQDRELSFDD-IMHYQKIIVALVETDRFMKE 119
Cdd:pfam18135 302 GK-SALEWLKDRYGVKLDKDSgILNDPNDWAKLDETEEILDL 342
 
Name Accession Description Interval E-value
Type_ISP_C pfam18135
Type ISP C-terminal specificity domain; This is the C-terminal domain of Type ISP ...
 1-119 2.28e-27

Type ISP C-terminal specificity domain; This is the C-terminal domain of Type ISP restriction-modification enzyme LLaBIII present in Lactococcus lactis subsp. cremoris. Type ISP restriction-modification (RM) enzymes provide a potent defence against infection by foreign and bacteriophage DNA. This domain interacts extensively with DNA and is known as the target recognition domain (TRD). TRD works by recognising 6/7 base pairs of asymmetric sequence.


Pssm-ID: 465663  Cd Length: 342  Bit Score: 103.10  E-value: 2.28e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278550848   1 WPLVSLGGQIRQLHLM-ES-PALDQAITPYPVAGSNVVsrkiskTSPGYEAIDDThGKVWINDNQYFDQVPLLAWEFYIG 78
Cdd:pfam18135 229 WELVELGRELADLHLNyERvAPLPPGITTYPPDGDYRV------EKMKYDKKKDK-GTIIINGEGTFTGVPPEAWEYVVG 301

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1278550848  79 GYqPAQKWLKDRQDRELSFDD-IMHYQKIIVALVETDRFMKE 119
Cdd:pfam18135 302 GK-SALEWLKDRYGVKLDKDSgILNDPNDWAKLDETEEILDL 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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