|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
1-749 |
0e+00 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 1099.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 1 MLNQLRDIVEHVSRVEDIHQALEVFVERTCDAINSECCTIYLSNHQKQRLELMATKGL-TFSGERLHIGFQEGLVGLVHR 79
Cdd:PRK11061 1 MLTRLREIVEKVASAPRLNEALDILVTETCLAMDTEVCSVYLADHDRRCYYLMATRGLkKPRGRTVTLAFDEGIVGLVGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 80 TAEPLNVAKASLHPDFKFFPQLGEDVYQAFLATPIVHRKRMLGVVVIQQKTPRLFSDTEESFLVTLAAQLAVLIASEQQQ 159
Cdd:PRK11061 81 LAEPINLADAQKHPSFKYIPSVKEERFRAFLGVPIIYRRQLLGVLVVQQRELRQFDESEESFLVTLATQLAAILSQSQLT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 160 GNWLlQERKSStVTGLSACNGIAIGPIWRGNDEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRLRKQLDSDLNKDA 239
Cdd:PRK11061 161 ALFG-QYRQTR-IRALPASPGVAIAEGWQDATQPLLEQVYPASTLDPALERERLTGALEEAANEFRRYSKRFAAGAQKET 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 240 LAIFDLFTHLLNDPKLRGDLIKQIDKGDAADWALRQVIERYSNHFARMNDIYLQERSQDVRELGQRLLYFLYHSQAKEIK 319
Cdd:PRK11061 239 AAIFDLYSHLLNDPRLRRELFAEVDKGSVAEWAVKQVIEKFAEQFAALSDNYLRERAGDLRALGQRLLFHLDDSEQGPNA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 320 LEKPVIFVVNELTTTLLASVPRDKLLGVISLQGGVNSHAAILSRALGIPSVIGSNLKGIEADDRHIILDGYSGEVLLNPT 399
Cdd:PRK11061 319 WPERFILVADELTATLLAELPQDRLAGVVVRDGAANSHAAILVRALGIPTVMGADIQPSLLHQRLLIVDGYRGELLVDPE 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 400 AKEMSDYQKLLAEEQEVRSMVESEVREPALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEISFIVKQAFPSEDE 479
Cdd:PRK11061 399 PVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSAEHEEKLGSRVDGVGLYRTEIPFMLQSGFPSEEE 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 480 QVETYRKVLAYSQGKPVVMRTLDIGGDKSLPYFPMEEENPFLGWRGIRFTLDHPDIFLIQVRAMMRASVGQKSeLKILLP 559
Cdd:PRK11061 479 QVAQYQGMLQMFPDKPVTLRTLDIGADKQLPYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGN-LSILLP 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 560 MISGVPELDSALSLIAQAYHEV-ALTHPRVKKPKVGIMLEVPSMIYLLPVIAKRIDFVSVGTNDLTQYLLAVDRNNSQVS 638
Cdd:PRK11061 558 MVTSIDEVDEARRLIDRAGREVeEMLGYEIPKPRIGIMIEVPSMVFMLPHLASRVDFISVGTNDLTQYLLAVDRNNTRVA 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 639 ELYEVVHPSVLMALKQIHDACRYSKIPVSICGELAGDPIGVLLLLGLGFKQLSMNSANVANIKYVIRQSNLDDLEALANQ 718
Cdd:PRK11061 638 SLYDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGDPMGALLLIGLGYRHLSMNGRSVARVKYLLRHIDLAEAENLAQR 717
|
730 740 750
....*....|....*....|....*....|.
gi 1326524000 719 AITKAYASDVHKLAFDYLEKRDLAGFVRPGK 749
Cdd:PRK11061 718 SLEAQLATEVRHQVAAFMERRGLGGLIRGGK 748
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
172-739 |
0e+00 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 555.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 172 VTGLSACNGIAIGPIWRGNDEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRLRKQLDSDLNKDALAIFDlfTHL-- 249
Cdd:COG1080 1 LKGIAASPGIAIGKAFLLREEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFD--AHLll 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 250 LNDPKLRGDLIKQIDKG-DAADWALRQVIERYSNHFARMNDIYLQERSQDVRELGQRLLYFLYHSQAKEI-KLEKPVIFV 327
Cdd:COG1080 79 LEDPELIEEVEELIREGrYNAEWALKEVIEELAAQFEALDDEYLRERAADIRDVGRRVLRNLLGVEAPDLsDLPEPVILV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 328 VNELTTTLLASVPRDKLLGVISLQGGVNSHAAILSRALGIPSVIG--SNLKGIEADDRhIILDGYSGEVLLNPTAKEMSD 405
Cdd:COG1080 159 AHDLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGlgDALLLVKDGDL-VIVDGDAGVVIVNPDEETLAE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 406 YQKLLAEEQEVRSMVESEVREPALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEISFIVKQAFPSEDEQVETYR 485
Cdd:COG1080 238 YRERQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYR 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 486 KVLAYSQGKPVVMRTLDIGGDKSLPYFPM-EEENPFLGWRGIRFTLDHPDIFLIQVRAMMRASVGQKseLKILLPMISGV 564
Cdd:COG1080 318 AVAEAMGGRPVTIRTLDIGGDKPLPYLPLpKEENPFLGLRAIRLCLDRPELFRTQLRAILRASAHGN--LRIMFPMISSV 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 565 PELDSALSLIAQAYHEVALT-HPRVKKPKVGIMLEVPSMIYLLPVIAKRIDFVSVGTNDLTQYLLAVDRNNSQVSELYEV 643
Cdd:COG1080 396 EELRQAKALLEEAKAELRAEgIPFDEDIPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDP 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 644 VHPSVLMALKQIHDACRYSKIPVSICGELAGDPI--------GVllllglgfKQLSMNSANVANIKYVIRQSNLDDLEAL 715
Cdd:COG1080 476 LHPAVLRLIKMVIDAAHKAGKPVGVCGEMAGDPLatplllglGL--------DELSMSPSSIPAVKAIIRRLDLAEARAL 547
|
570 580
....*....|....*....|....
gi 1326524000 716 ANQAITKAYASDVHKLAFDYLEKR 739
Cdd:COG1080 548 AEKALALDTAEEVRALLEEFLAEL 571
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
172-731 |
1.29e-118 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 368.35 E-value: 1.29e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 172 VTGLSACNGIAIGPIWRGNDEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRLRKQLDSDLNKDALAIFDLFTHLLN 251
Cdd:TIGR01417 1 ISGIGVSPGIAIGKALLLKKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 252 DPKLRGDLIKQIDKGD-AADWALRQVIERYSNHFARMNDIYLQERSQDVRELGQRLLYFLYHSQAKE-IKLEKPVIFVVN 329
Cdd:TIGR01417 81 DPELTEEVIELIKKDHkNAEFAAHEVFEGQAKSLEEMDDEYLKERAADIRDIGNRLLGHLLGVKISDlSEIQDEVILVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 330 ELTTTLLASVPRDKLLGVISLQGGVNSHAAILSRALGIPSVIG-SNLKGIEADDRHIILDGYSGEVLLNPTAKEMSDYQk 408
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGtKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYE- 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 409 llaEEQEVRSMVESE----VREPALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEISFIVKQAFPSEDEQVETY 484
Cdd:TIGR01417 240 ---AKQEAVSSEKAElaklKDKPAITLDGHQVELAANIGTVDDVEGAERNGGEGIGLFRTEFLYMSRDQLPTEEEQFAAY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 485 RKVLAYSQGKPVVMRTLDIGGDKSLPYFPM-EEENPFLGWRGIRFTLDHPDIFLIQVRAMMRASVGQKseLKILLPMISG 563
Cdd:TIGR01417 317 KTVLEAMESDAVIVRTLDIGGDKELPYLNFpKEENPFLGYRAIRLALEREEILRTQLRAILRASAYGK--LRIMFPMVAT 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 564 VPELDSALSLIAQAYHE-VALTHPRVKKPKVGIMLEVPSMIYLLPVIAKRIDFVSVGTNDLTQYLLAVDRNNSQVSELYE 642
Cdd:TIGR01417 395 VEEIRAVKQELEEEKQElNDEGKAFDENIEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDRGNDLISNLYQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 643 VVHPSVLMALKQIHDACRYSKIPVSICGELAGDPIGVLLLLGLGFKQLSMNSANVANIKYVIRQSNLDDLEALANQAITK 722
Cdd:TIGR01417 475 PYNPAVLRLIKLVIDAAKAEGIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIKMIIRKLNIEECKSLAEKALAQ 554
|
....*....
gi 1326524000 723 AYASDVHKL 731
Cdd:TIGR01417 555 PTTEEVHKL 563
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
427-709 |
9.80e-104 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 319.64 E-value: 9.80e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 427 PALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEISFIVKQAFPSEDEQVETYRKVLAYSQGKPVVMRTLDIGGD 506
Cdd:pfam02896 11 PAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDEQFEAYKGVLEAMNGRPVTVRTLDIGGD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 507 KSLPYFPM-EEENPFLGWRGIRFTLDHPDIFLIQVRAMMRASVGQKseLKILLPMISGVPELDSALSLIAQAYHEVALTH 585
Cdd:pfam02896 91 KELPYLEEpEEMNPFLGWRGIRIGLDRPELFRTQLRAILRASAFGN--LRIMFPMVASVEELREAKAIIEEVKEELDAEV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 586 PRVKKPKVGIMLEVPSMIYLLPVIAKRIDFVSVGTNDLTQYLLAVDRNNSQVSELYEVVHPSVLMALKQIHDACRYSKIP 665
Cdd:pfam02896 169 GFDKDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNERVAYLYDPLHPAVLRLIKEVIRAAHRHGKW 248
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1326524000 666 VSICGELAGDPIGVLLLLGLGFKQLSMNSANVANIKYVIRQSNL 709
Cdd:pfam02896 249 VGICGEMAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQIDR 292
|
|
| GAF |
smart00065 |
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these ... |
17-158 |
2.93e-16 |
|
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these domains in PDE6B result in autosomal recessive inheritance of retinitis pigmentosa.
Pssm-ID: 214500 [Multi-domain] Cd Length: 149 Bit Score: 76.27 E-value: 2.93e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 17 DIHQALEVFVERTCDAINSECCTIYLSNH-QKQRLELMATKGLTFSGERLHIGFQEGLVGLVHRTAEPLNVAKASLHPDF 95
Cdd:smart00065 1 DLEELLQTILEELRQLLGADRVLIYLVDEnDRGELVLVAADGLTLPTLGIRFPLDEGLAGRVAETGRPLNIPDVEADPLF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1326524000 96 KFFPQLGEDVYQAFLATPIVHRKRMLGVVVIQQKT-PRLFSDTEESFLVTLAAQLAVLIASEQQ 158
Cdd:smart00065 81 AEDLLGRYQGVRSFLAVPLVADGELVGVLALHNKKsPRPFTEEDEELLQALANQLAIALANAQL 144
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
1-749 |
0e+00 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 1099.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 1 MLNQLRDIVEHVSRVEDIHQALEVFVERTCDAINSECCTIYLSNHQKQRLELMATKGL-TFSGERLHIGFQEGLVGLVHR 79
Cdd:PRK11061 1 MLTRLREIVEKVASAPRLNEALDILVTETCLAMDTEVCSVYLADHDRRCYYLMATRGLkKPRGRTVTLAFDEGIVGLVGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 80 TAEPLNVAKASLHPDFKFFPQLGEDVYQAFLATPIVHRKRMLGVVVIQQKTPRLFSDTEESFLVTLAAQLAVLIASEQQQ 159
Cdd:PRK11061 81 LAEPINLADAQKHPSFKYIPSVKEERFRAFLGVPIIYRRQLLGVLVVQQRELRQFDESEESFLVTLATQLAAILSQSQLT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 160 GNWLlQERKSStVTGLSACNGIAIGPIWRGNDEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRLRKQLDSDLNKDA 239
Cdd:PRK11061 161 ALFG-QYRQTR-IRALPASPGVAIAEGWQDATQPLLEQVYPASTLDPALERERLTGALEEAANEFRRYSKRFAAGAQKET 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 240 LAIFDLFTHLLNDPKLRGDLIKQIDKGDAADWALRQVIERYSNHFARMNDIYLQERSQDVRELGQRLLYFLYHSQAKEIK 319
Cdd:PRK11061 239 AAIFDLYSHLLNDPRLRRELFAEVDKGSVAEWAVKQVIEKFAEQFAALSDNYLRERAGDLRALGQRLLFHLDDSEQGPNA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 320 LEKPVIFVVNELTTTLLASVPRDKLLGVISLQGGVNSHAAILSRALGIPSVIGSNLKGIEADDRHIILDGYSGEVLLNPT 399
Cdd:PRK11061 319 WPERFILVADELTATLLAELPQDRLAGVVVRDGAANSHAAILVRALGIPTVMGADIQPSLLHQRLLIVDGYRGELLVDPE 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 400 AKEMSDYQKLLAEEQEVRSMVESEVREPALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEISFIVKQAFPSEDE 479
Cdd:PRK11061 399 PVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSAEHEEKLGSRVDGVGLYRTEIPFMLQSGFPSEEE 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 480 QVETYRKVLAYSQGKPVVMRTLDIGGDKSLPYFPMEEENPFLGWRGIRFTLDHPDIFLIQVRAMMRASVGQKSeLKILLP 559
Cdd:PRK11061 479 QVAQYQGMLQMFPDKPVTLRTLDIGADKQLPYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGN-LSILLP 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 560 MISGVPELDSALSLIAQAYHEV-ALTHPRVKKPKVGIMLEVPSMIYLLPVIAKRIDFVSVGTNDLTQYLLAVDRNNSQVS 638
Cdd:PRK11061 558 MVTSIDEVDEARRLIDRAGREVeEMLGYEIPKPRIGIMIEVPSMVFMLPHLASRVDFISVGTNDLTQYLLAVDRNNTRVA 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 639 ELYEVVHPSVLMALKQIHDACRYSKIPVSICGELAGDPIGVLLLLGLGFKQLSMNSANVANIKYVIRQSNLDDLEALANQ 718
Cdd:PRK11061 638 SLYDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGDPMGALLLIGLGYRHLSMNGRSVARVKYLLRHIDLAEAENLAQR 717
|
730 740 750
....*....|....*....|....*....|.
gi 1326524000 719 AITKAYASDVHKLAFDYLEKRDLAGFVRPGK 749
Cdd:PRK11061 718 SLEAQLATEVRHQVAAFMERRGLGGLIRGGK 748
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
172-739 |
0e+00 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 555.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 172 VTGLSACNGIAIGPIWRGNDEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRLRKQLDSDLNKDALAIFDlfTHL-- 249
Cdd:COG1080 1 LKGIAASPGIAIGKAFLLREEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFD--AHLll 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 250 LNDPKLRGDLIKQIDKG-DAADWALRQVIERYSNHFARMNDIYLQERSQDVRELGQRLLYFLYHSQAKEI-KLEKPVIFV 327
Cdd:COG1080 79 LEDPELIEEVEELIREGrYNAEWALKEVIEELAAQFEALDDEYLRERAADIRDVGRRVLRNLLGVEAPDLsDLPEPVILV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 328 VNELTTTLLASVPRDKLLGVISLQGGVNSHAAILSRALGIPSVIG--SNLKGIEADDRhIILDGYSGEVLLNPTAKEMSD 405
Cdd:COG1080 159 AHDLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGlgDALLLVKDGDL-VIVDGDAGVVIVNPDEETLAE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 406 YQKLLAEEQEVRSMVESEVREPALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEISFIVKQAFPSEDEQVETYR 485
Cdd:COG1080 238 YRERQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYR 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 486 KVLAYSQGKPVVMRTLDIGGDKSLPYFPM-EEENPFLGWRGIRFTLDHPDIFLIQVRAMMRASVGQKseLKILLPMISGV 564
Cdd:COG1080 318 AVAEAMGGRPVTIRTLDIGGDKPLPYLPLpKEENPFLGLRAIRLCLDRPELFRTQLRAILRASAHGN--LRIMFPMISSV 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 565 PELDSALSLIAQAYHEVALT-HPRVKKPKVGIMLEVPSMIYLLPVIAKRIDFVSVGTNDLTQYLLAVDRNNSQVSELYEV 643
Cdd:COG1080 396 EELRQAKALLEEAKAELRAEgIPFDEDIPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDP 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 644 VHPSVLMALKQIHDACRYSKIPVSICGELAGDPI--------GVllllglgfKQLSMNSANVANIKYVIRQSNLDDLEAL 715
Cdd:COG1080 476 LHPAVLRLIKMVIDAAHKAGKPVGVCGEMAGDPLatplllglGL--------DELSMSPSSIPAVKAIIRRLDLAEARAL 547
|
570 580
....*....|....*....|....
gi 1326524000 716 ANQAITKAYASDVHKLAFDYLEKR 739
Cdd:COG1080 548 AEKALALDTAEEVRALLEEFLAEL 571
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
172-731 |
1.29e-118 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 368.35 E-value: 1.29e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 172 VTGLSACNGIAIGPIWRGNDEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRLRKQLDSDLNKDALAIFDLFTHLLN 251
Cdd:TIGR01417 1 ISGIGVSPGIAIGKALLLKKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 252 DPKLRGDLIKQIDKGD-AADWALRQVIERYSNHFARMNDIYLQERSQDVRELGQRLLYFLYHSQAKE-IKLEKPVIFVVN 329
Cdd:TIGR01417 81 DPELTEEVIELIKKDHkNAEFAAHEVFEGQAKSLEEMDDEYLKERAADIRDIGNRLLGHLLGVKISDlSEIQDEVILVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 330 ELTTTLLASVPRDKLLGVISLQGGVNSHAAILSRALGIPSVIG-SNLKGIEADDRHIILDGYSGEVLLNPTAKEMSDYQk 408
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGtKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYE- 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 409 llaEEQEVRSMVESE----VREPALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEISFIVKQAFPSEDEQVETY 484
Cdd:TIGR01417 240 ---AKQEAVSSEKAElaklKDKPAITLDGHQVELAANIGTVDDVEGAERNGGEGIGLFRTEFLYMSRDQLPTEEEQFAAY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 485 RKVLAYSQGKPVVMRTLDIGGDKSLPYFPM-EEENPFLGWRGIRFTLDHPDIFLIQVRAMMRASVGQKseLKILLPMISG 563
Cdd:TIGR01417 317 KTVLEAMESDAVIVRTLDIGGDKELPYLNFpKEENPFLGYRAIRLALEREEILRTQLRAILRASAYGK--LRIMFPMVAT 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 564 VPELDSALSLIAQAYHE-VALTHPRVKKPKVGIMLEVPSMIYLLPVIAKRIDFVSVGTNDLTQYLLAVDRNNSQVSELYE 642
Cdd:TIGR01417 395 VEEIRAVKQELEEEKQElNDEGKAFDENIEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDRGNDLISNLYQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 643 VVHPSVLMALKQIHDACRYSKIPVSICGELAGDPIGVLLLLGLGFKQLSMNSANVANIKYVIRQSNLDDLEALANQAITK 722
Cdd:TIGR01417 475 PYNPAVLRLIKLVIDAAKAEGIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIKMIIRKLNIEECKSLAEKALAQ 554
|
....*....
gi 1326524000 723 AYASDVHKL 731
Cdd:TIGR01417 555 PTTEEVHKL 563
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
172-741 |
1.99e-108 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 341.99 E-value: 1.99e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 172 VTGLSACNGIAIGPIWRGNDEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRLRKQLDSDLNKDALAIFDLFTHLLN 251
Cdd:PRK11177 2 ISGILASPGIAFGKALLLKEDEIVINRKKISADQVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLLE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 252 DPKLRGDLIKQI-DKGDAADWALRQVIERYSNHFARMNDIYLQERSQDVRELGQRLLyflyhsqaKEI---------KLE 321
Cdd:PRK11177 82 DEELEQEIIALIkDKHMTADAAAHSVIEGQAKALEELDDEYLKERAADVRDIGKRLL--------KNIlglkiidlsAIQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 322 KPVIFVVNELTTTLLASVPRDKLLGVISLQGGVNSHAAILSRALGIPSVIGSN--LKGIEADDrHIILDGYSGEVLLNPT 399
Cdd:PRK11177 154 EEVILVAADLTPSETAQLNLKKVLGFITDIGGRTSHTSIMARSLELPAIVGTGniTKQVKNGD-YLILDAVNNQIYVNPT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 400 AKEmsdyqklLAEEQEVRSMVESEVRE-------PALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEISFIVKQ 472
Cdd:PRK11177 233 NEV-------IEELKAVQEQYASEKAElaklkdlPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRD 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 473 AFPSEDEQVETYRKVLAYSQGKPVVMRTLDIGGDKSLPY--FPmEEENPFLGWRGIRFTLDHPDIFLIQVRAMMRASVGQ 550
Cdd:PRK11177 306 ALPTEEEQFQAYKAVAEAMGSQAVIVRTMDIGGDKELPYmnLP-KEENPFLGWRAIRIAMDRKEILHDQLRAILRASAFG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 551 KseLKILLPMISGVPE---LDSALSLIAQAYHEVAltHPRVKKPKVGIMLEVPSMIYLLPVIAKRIDFVSVGTNDLTQYL 627
Cdd:PRK11177 385 K--LRIMFPMIISVEEvreLKAEIEILKQELRDEG--KAFDESIEIGVMVETPAAAVIARHLAKEVDFFSIGTNDLTQYT 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 628 LAVDRNNSQVSELYEVVHPSVLMALKQIHDACRYSKIPVSICGELAGDPIGVLLLLGLGFKQLSMNSANVANIKYVIRQS 707
Cdd:PRK11177 461 LAVDRGNELISHLYNPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNT 540
|
570 580 590
....*....|....*....|....*....|....
gi 1326524000 708 NLDDLEALANQAITKAYASDVHKLAFDYLEKRDL 741
Cdd:PRK11177 541 NFEDAKALAEQALAQPTADELMTLVNKFIEEKTL 574
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
427-709 |
9.80e-104 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 319.64 E-value: 9.80e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 427 PALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEISFIVKQAFPSEDEQVETYRKVLAYSQGKPVVMRTLDIGGD 506
Cdd:pfam02896 11 PAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDEQFEAYKGVLEAMNGRPVTVRTLDIGGD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 507 KSLPYFPM-EEENPFLGWRGIRFTLDHPDIFLIQVRAMMRASVGQKseLKILLPMISGVPELDSALSLIAQAYHEVALTH 585
Cdd:pfam02896 91 KELPYLEEpEEMNPFLGWRGIRIGLDRPELFRTQLRAILRASAFGN--LRIMFPMVASVEELREAKAIIEEVKEELDAEV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 586 PRVKKPKVGIMLEVPSMIYLLPVIAKRIDFVSVGTNDLTQYLLAVDRNNSQVSELYEVVHPSVLMALKQIHDACRYSKIP 665
Cdd:pfam02896 169 GFDKDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNERVAYLYDPLHPAVLRLIKEVIRAAHRHGKW 248
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1326524000 666 VSICGELAGDPIGVLLLLGLGFKQLSMNSANVANIKYVIRQSNL 709
Cdd:pfam02896 249 VGICGEMAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQIDR 292
|
|
| PtsP |
COG3605 |
Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms]; |
1-160 |
8.38e-55 |
|
Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms];
Pssm-ID: 442824 [Multi-domain] Cd Length: 188 Bit Score: 186.64 E-value: 8.38e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 1 MLNQLRDIVEHVSRVEDIHQALEVFVERTCDAINSECCTIYLSNHQKQRLELMATKGLT---FSGERLHIGfqEGLVGLV 77
Cdd:COG3605 2 MLKALRRISEAVASALDLDEALDRIVRRIAEALGVDVCSIYLLDPDGGRLELRATEGLNpeaVGKVRLPLG--EGLVGLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 78 HRTAEPLNVAKASLHPDFKFFPQLGEDVYQAFLATPIVHRKRMLGVVVIQQKTPRLFSDTEESFLVTLAAQLAVLIASEQ 157
Cdd:COG3605 80 AERGEPLNLADAASHPRFKYFPETGEEGFRSFLGVPIIRRGRVLGVLVVQSREPREFTEEEVEFLVTLAAQLAEAIANAE 159
|
...
gi 1326524000 158 QQG 160
Cdd:COG3605 160 LLG 162
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
346-671 |
2.37e-41 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 162.21 E-value: 2.37e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 346 GVISLQGGVNSHAAILSRALGIPSVIGS-NLKGIEADDRHIILDGYSGEvllnptakEMSDYQKLLaeeqevrsmvESEV 424
Cdd:TIGR01418 406 AIVTNEGGMTCHAAIVARELGIPAVVGTgDATKTLKDGMEVTVDCAEGD--------TGYVYAGKL----------EHEV 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 425 REPALTSDKVPIT-ILLNAGLgGDASYSFFDV-VDGVGLYRTEisFIV------------KQAFPSEDEQVET------- 483
Cdd:TIGR01418 468 KEVELSNMPVTATkIYMNVGN-PEVAFRFAALpNDGVGLARIE--FIIlnwigkhplaliDDDDLESVEKNEIeelmagn 544
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 484 ----YRKVLAYSQG--------KPVVMRTLD---------IGGDKSLPyfpmEEENPFLGWRGIRFTLD--HPDIFLIQV 540
Cdd:TIGR01418 545 prdfFVDKLAEGIAkvaaafypKPVIVRTSDfksneyrnlIGGEEYEP----DEENPMLGWRGASRYYSesYEEAFRLEC 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 541 RAM--MRASVGQKSeLKILLPMISGVPELDSALSLIAQAyhevALthPRVKKP-KVGIMLEVPSMIYLLPVIAKRIDFVS 617
Cdd:TIGR01418 621 RAIkrVREEMGLTN-VEVMIPFVRTPEEGKRALEIMAEE----GL--RRGKNGlEVYVMCEVPSNALLADEFAKEFDGFS 693
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1326524000 618 VGTNDLTQYLLAVDRNNSQVSELYEVVHPSVLMALKQIHDACRYSKIPVSICGE 671
Cdd:TIGR01418 694 IGSNDLTQLTLGVDRDSGLVAHLFDERNPAVLRLIEMAIKAAKEHGKKVGICGQ 747
|
|
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
351-670 |
4.31e-39 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 155.29 E-value: 4.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 351 QGGVNSHAAILSRALGIPSVIGSN-----LKgieadDRHII----LDGYSGEVllnptakemsdYQKLLaeeqevrsmvE 421
Cdd:PRK06464 412 RGGRTCHAAIIARELGIPAVVGTGnatevLK-----DGQEVtvscAEGDTGYV-----------YEGLL----------E 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 422 SEVREPALtsDKVPIT---ILLNAGLGgDASYSFFDV-VDGVGLYRTEisFI-------------------------VKQ 472
Cdd:PRK06464 466 FEVEEVSL--EEMPETptkIMMNVGNP-ERAFDFAALpNDGVGLARLE--FIinnmigvhplallefdqqdadlkaeIEE 540
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 473 AFPSEDEQVETYRKVLAysQG----------KPVVMRTLD---------IGGDKslpyFPMEEENPFLGWRGIRFTLDHP 533
Cdd:PRK06464 541 LTAGYASPEEFYVDKLA--EGiatvaaafypKPVIVRLSDfksneyanlIGGER----YEPEEENPMLGFRGASRYLSES 614
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 534 --DIFLIQVRAM--MRASVGQKSeLKILLPMISGVPELDSALSLIAqayhEVALtHPRVKKPKVGIMLEVPSMIYLLPVI 609
Cdd:PRK06464 615 frEAFALECEAIkrVREEMGLTN-VEVMIPFVRTVEEAEKVIELLA----ENGL-KRGENGLKVIMMCEIPSNALLAEEF 688
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1326524000 610 AKRIDFVSVGTNDLTQYLLAVDRNNSQVSELYEVVHPSVLMALKQIHDACRYSKIPVSICG 670
Cdd:PRK06464 689 LEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLFDERNPAVKKLISMAIKAAKKAGKYVGICG 749
|
|
| PEP-utilizers_N |
pfam05524 |
PEP-utilizing enzyme, N-terminal; |
173-295 |
1.41e-24 |
|
PEP-utilizing enzyme, N-terminal;
Pssm-ID: 461671 [Multi-domain] Cd Length: 125 Bit Score: 99.22 E-value: 1.41e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 173 TGLSACNGIAIGPIWR-GNDEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRLRKQLDSDLNKDALAIFDLFTHLLN 251
Cdd:pfam05524 1 KGIGASPGIAIGKAVVlEEPELEVPDEREVPADDVEAEIARLEAALEAAREELEALAERAAGELGEEEAAIFEAHLMMLE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1326524000 252 DPKLRGDLIKQIDKGDA-ADWALRQVIERYSNHFARMNDIYLQER 295
Cdd:pfam05524 81 DPELLEEVEELIREGGLnAEAAVKEVVDEFAAMFEAMDDPYLRER 125
|
|
| PRK11377 |
PRK11377 |
dihydroxyacetone kinase subunit M; Provisional |
166-396 |
1.14e-21 |
|
dihydroxyacetone kinase subunit M; Provisional
Pssm-ID: 183108 [Multi-domain] Cd Length: 473 Bit Score: 99.05 E-value: 1.14e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 166 ERKSSTVTGLSACNGIAIGPIWRGndEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRLRKQLDSDLNKDALAIFDL 245
Cdd:PRK11377 241 ETEEVAPPTLRPVPSPVSGKAFYY--QPVLCTVQAKSTLTVEEEQERLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSG 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 246 FTHLLNDPKLRGDLIKQI-DKGDAADWALRQVIERYSNHFARMNDIYLQERSQDVRELGQRLLYFLYHSQAKEIKLEKPV 324
Cdd:PRK11377 319 HHTLLDDPELLAAASERLqHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQFNSPT 398
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1326524000 325 IFVVNELTTTLLASVPRDKLLGvISLQGGVN-SHAAILSRALGIPSVIGSN--LKGIEADDRhIILDGYSGEVLL 396
Cdd:PRK11377 399 ILLAENIYPSTVLQLDPAVVKG-ICLSAGSPlSHSAIIARELGIGWICQQGekLYAIQPEET-LTLDVKTQRLNR 471
|
|
| GAF |
COG2203 |
GAF domain [Signal transduction mechanisms]; |
2-488 |
1.19e-16 |
|
GAF domain [Signal transduction mechanisms];
Pssm-ID: 441805 [Multi-domain] Cd Length: 712 Bit Score: 84.47 E-value: 1.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 2 LNQLRDIVEHVSRVEDIHQALEVFVERTCDAINSECCTIYLSNHQKQRLELMATKGLTfSGERLHIGFQEGLVGLVHRTA 81
Cdd:COG2203 192 LALLNEISQALRSALDLEELLQRILELAGELLGADRGAILLVDEDGGELELVAAPGLP-EEELGRLPLGEGLAGRALRTG 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 82 EPLNVAKASLHPDFKFFPQ--LGEDVYQAFLATPIVHRKRMLGVVVIQQKTPRLFSDTEESFLVTLAAQLAVLI------ 153
Cdd:COG2203 271 EPVVVNDASTDPRFAPSLRelLLALGIRSLLCVPLLVDGRLIGVLALYSKEPRAFTEEDLELLEALADQAAIAIerarly 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 154 ------ASEQQQGNWLLQERKSSTVTGLSACNGIAIGPIWRGNDEPLLKDVSPASAIDIEKDKEWLLVAIESALTEFRRL 227
Cdd:COG2203 351 ealeaaLAALLQELALLRLLLDLELTLLRLRQLLLELLLALLLLLSLLGAELLLLLLDAADLSGLLALEGLLLLDLLLLL 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 228 RKQLDSDLNKDALAIFDLFTHLLNDPKLRGDLIKQIDKGDAADWALRQVIERYSNHFARMNDIYLQERSQDVRELGQRLL 307
Cdd:COG2203 431 LLLRRILLLRVLRRLLLGDEEGLVLLLALAELELLEILELLVLLAVILLALALLAALLLLLLLLLALLALSALAVLASLL 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 308 YFLYHSQAKEIKLEKPVIFVVNELTTTLLASvprdkLLGVISLQGGVNSHAAILSRALGIPSVIGSNLKGIEADDRHIIL 387
Cdd:COG2203 511 LALLLLLLLLLLLLLLGLLAALAADLLLLAA-----ALLEDLLILLLVLLLERELLTLVGVLLLLGLSVLLIELALALIL 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 388 DGYSGEVLLNPTAKEMSDYQKLLAEEQEVRSMVESEVREPALTSDKVPITILLNAGLGGDASYSFFDVVDGVGLYRTEIS 467
Cdd:COG2203 586 ALALLELLLVAVGDLLLLERDLLLLLVLLVRLLLELLVVTLELTVLVVLAAVEDSALLLRLALALASLVLLRALLATELD 665
|
490 500
....*....|....*....|.
gi 1326524000 468 FIVKQAFPSEDEQVETYRKVL 488
Cdd:COG2203 666 LILDSSLLLGLLLLGALLLLG 686
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
319-392 |
1.65e-16 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 74.37 E-value: 1.65e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1326524000 319 KLEKPVIFVVNELTTTLLASVprDKLLGVISLQGGVNSHAAILSRALGIPSVIG-SNLKGIEADDRHIILDGYSG 392
Cdd:pfam00391 1 KLPEGVILVAPDTTPSDTAGL--DKAAGIVTERGGMTSHAAIVARELGIPAVVGvGDATILLKEGDLVTVDGSTG 73
|
|
| GAF |
smart00065 |
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these ... |
17-158 |
2.93e-16 |
|
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these domains in PDE6B result in autosomal recessive inheritance of retinitis pigmentosa.
Pssm-ID: 214500 [Multi-domain] Cd Length: 149 Bit Score: 76.27 E-value: 2.93e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 17 DIHQALEVFVERTCDAINSECCTIYLSNH-QKQRLELMATKGLTFSGERLHIGFQEGLVGLVHRTAEPLNVAKASLHPDF 95
Cdd:smart00065 1 DLEELLQTILEELRQLLGADRVLIYLVDEnDRGELVLVAADGLTLPTLGIRFPLDEGLAGRVAETGRPLNIPDVEADPLF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1326524000 96 KFFPQLGEDVYQAFLATPIVHRKRMLGVVVIQQKT-PRLFSDTEESFLVTLAAQLAVLIASEQQ 158
Cdd:smart00065 81 AEDLLGRYQGVRSFLAVPLVADGELVGVLALHNKKsPRPFTEEDEELLQALANQLAIALANAQL 144
|
|
| GAF |
pfam01590 |
GAF domain; This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl ... |
17-153 |
8.51e-13 |
|
GAF domain; This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54. This domain can bind biliverdine and phycocyanobilin (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 460259 [Multi-domain] Cd Length: 133 Bit Score: 65.96 E-value: 8.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 17 DIHQALEVFVERTCDAINSECCTIYLSNHQkqrLELMATKGLTFSGERLHIgFQEGLVGLVHRTAEPLNVAKASLHPDFK 96
Cdd:pfam01590 1 DLEEILQTILEELRELLGADRCALYLPDAD---GLEYLPPGARWLKAAGLE-IPPGTGVTVLRTGRPLVVPDAAGDPRFL 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1326524000 97 FFPQLGEDV-YQAFLATPIVHRKRMLGVVVIQQKTPRlFSDTEESFLVTLAAQLAVLI 153
Cdd:pfam01590 77 DPLLLLRNFgIRSLLAVPIIDDGELLGVLVLHHPRPP-FTEEELELLEVLADQVAIAL 133
|
|
| GAF_2 |
pfam13185 |
GAF domain; The GAF domain is named after some of the proteins it is found in, including ... |
19-154 |
2.09e-11 |
|
GAF domain; The GAF domain is named after some of the proteins it is found in, including cGMP-specific phosphodiesterases, adenylyl cyclases and FhlA. It is also found in guanylyl cyclases and phytochromes. The structure of a GAF domain shows that the domain shares a similar fold with the PAS domain. This domain can bind O2, CO and NO (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 433019 [Multi-domain] Cd Length: 137 Bit Score: 62.10 E-value: 2.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 19 HQALEVFVERTCDAI----NSECCTIYLSNHQKQRLElmATKGLTFSGERLHIGFQEGLVGLVHRTAEPLNVAKASLHPD 94
Cdd:pfam13185 1 AADLEELLDAVLEAAvelgASAVGFILLVDDDGRLAA--WGGAADELSAALDDPPGEGLVGEALRTGRPVIVNDLAADPA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 95 FKFFPQLGEDvYQAFLATPIVHRKRMLGVVVIQQKTPRLFSDTEESFLVTLAAQLAVLIA 154
Cdd:pfam13185 79 KKGLPAGHAG-LRSFLSVPLVSGGRVVGVLALGSNRPGAFDEEDLELLELLAEQAAIAIE 137
|
|
| GAF_3 |
pfam13492 |
GAF domain; |
26-150 |
1.88e-06 |
|
GAF domain;
Pssm-ID: 433253 [Multi-domain] Cd Length: 129 Bit Score: 47.75 E-value: 1.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 26 VERTCDAINSECCTIYLSNHQKQRLELMATkglTFSGERLHIGF--QEGLVGLVHRTAEPLNVAKAslhPDFKFFPQlge 103
Cdd:pfam13492 10 LKLLVRLLGAERAAVYLLDEDGNKLQVAAG---YDGEPDPSESLdaDSPLARRALSSGEPISGLGS---AGEDGLPD--- 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1326524000 104 dvyQAFLATPIVHRKRMLGVVVIQQKTPRLFSDTEESFLVTLAAQLA 150
Cdd:pfam13492 81 ---GPALVVPLVAGRRVIGVLALASSKPRAFDAEDLRLLESLAAQIA 124
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
346-394 |
6.99e-06 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 49.36 E-value: 6.99e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1326524000 346 GVISLQGGVNSHAAILSRALGIPSVIGSNLKGIEA-DDRHIILDGYSGEV 394
Cdd:PRK05878 402 GIVTEVGGATSHAAVVSRELGRVAVVGCGAGVAAAlAGKEITVDGYEGEV 451
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
346-394 |
1.47e-05 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 48.29 E-value: 1.47e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1326524000 346 GVISLQGGVNSHAAILSRALGIPSVIG--SNLKGIEADDRhIILDGYSGEV 394
Cdd:COG0574 405 GIVTERGGMTSHAAIVARELGIPAVVGcgDATRVLKDGDE-ITVDGTTGEV 454
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
343-394 |
5.65e-05 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 46.05 E-value: 5.65e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1326524000 343 KLLGVISLQGGVNSHAAILSRALGIPSVIG-----SNLKgieaDDRHIILDG-----YSGEV 394
Cdd:COG3848 261 KAAGIITEEGGLTSHAAIVGLELGIPVIVGaegatEILK----DGQVVTVDAergvvYRGAV 318
|
|
| FhlA |
COG3604 |
FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis ... |
61-156 |
5.77e-05 |
|
FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 442823 [Multi-domain] Cd Length: 338 Bit Score: 45.99 E-value: 5.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326524000 61 SGERLHIGFQEGLVGLVHRTAEPLNVAKASLHPDFKFFPQLGEDVYQAFLATPIVHRKRMLGVVVIQQKTPRLFSDTEES 140
Cdd:COG3604 28 LALLLRGDLLASALVLEESLELLALALSEALLAAQARQAALAARERQLFLGVPLRVGGEVLGVLTLDSRRPGAFSEEDLR 107
|
90
....*....|....*.
gi 1326524000 141 FLVTLAAQLAVLIASE 156
Cdd:COG3604 108 LLETLASLAAVAILGE 123
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
343-394 |
7.75e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 42.72 E-value: 7.75e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1326524000 343 KLLGVISLQGGVNSHAAILSRALGIPSVIGSNL--KGIEADDRhIILDGYSGEV 394
Cdd:PRK08296 547 KIKATVTDIGGVMSHAAIVCREYGLPAVVGTGNatKRIKTGQR-LRVDGTKGVV 599
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
346-372 |
4.38e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 40.35 E-value: 4.38e-03
10 20
....*....|....*....|....*..
gi 1326524000 346 GVISLQGGVNSHAAILSRALGIPSVIG 372
Cdd:PRK05849 730 GLITCYGGANSHMAIRAAELGLPAVIG 756
|
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