|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
1-246 |
8.37e-74 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 225.40 E-value: 8.37e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 1 MLKHKKKLF--FIFVSIFLLAGCDSANVIQSSHTHFLDHYFIYPFSLLILFIGNtWLHQSVGFSIMLVTVGVRMLLAPLN 78
Cdd:PRK01622 1 MLKSYRAVLvsLSLLLVLVLSGCSNAAPIDAHSDGFFDHYFVYPFSFLIQFVAH-HIGGSYGIAIIIVTLIIRSLMIPLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 79 ILQYKNQLSN----KRIQPQLQQLKEKYK-NKDPESQQQYQREMMELLKENGANPL-MGCLPLLVQLPVFSIVYYAIRRI 152
Cdd:PRK01622 80 VSQYKSQRGMqekmAVMKPELDKIQAKLKvTKDLEKQKEYQKEMMELYKSGNINPLaMGCLPLLIQMPILSAFYYAIRRT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 153 DEISASSFLWLDLGHADpyFILPIAAALATYLQTRVMQTGAE-GMNGSHAVLSQILSPVMVLSFGVFSPSGLVLYWMTGS 231
Cdd:PRK01622 160 EEIASHSFLWFNLGHAD--HILPIIAGLTYFIQMKVSQSNGTsPEQVQMLKIQGIMMPAMILFMSFAAPSALVLYWITGG 237
|
250
....*....|....*
gi 1330666480 232 LFMIFQSLVLKKVFQ 246
Cdd:PRK01622 238 LFLMGQTIVLRKVME 252
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
60-243 |
9.87e-63 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 194.52 E-value: 9.87e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 60 GFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNKdpesQQQYQREMMELLKENGANPLMGCLPLLVQL 139
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDD----KQKLQQEMMKLYKEHGVNPLGGCLPLLIQM 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 140 PVFSIVYYAIRRIDEISASSFLW--LDLGHADPYFILPIAAALATYLQTRVMQTGAEGMNGSHAVLsQILSPVMVLSFGV 217
Cdd:cd20070 77 PIFIALYQVLRNSIELRGAPFLWwiLDLSAPDPYYILPILMGVTMFLQQKLTPTPTDDQAPQQKMM-MYFMPVMFTFIFL 155
|
170 180
....*....|....*....|....*.
gi 1330666480 218 FSPSGLVLYWMTGSLFMIFQSLVLKK 243
Cdd:cd20070 156 SFPSGLVLYWLVSNLFSIIQQLIINK 181
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
37-249 |
5.97e-62 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 193.41 E-value: 5.97e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 37 HYFIYPFSLLILFIGNTWLhqSVGFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNkdpeSQQQYQRE 116
Cdd:COG0706 7 GFIAKPLFWLLNFLHSLVG--NWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKD----DPQKLQQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 117 MMELLKENGANPLMGCLPLLVQLPVFSIVYYAIRRIDEISASSFLWL-DLGHADPYFI-LPIAAALATYLQTRVMQTGAe 194
Cdd:COG0706 81 MMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPFLGIpDLSAPDPYYIfLPILMGVTMFLQQKLNPAPA- 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1330666480 195 gMNGSHAVLSQILsPVMVLSFGVFSPSGLVLYWMTGSLFMIFQSLVLKKVFQEKA 249
Cdd:COG0706 160 -QDPQQKKMMYIM-PLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDKKK 212
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
58-241 |
4.85e-60 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 187.69 E-value: 4.85e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 58 SVGFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNkdpeSQQQYQREMMELLKENGANPLMGCLPLLV 137
Cdd:TIGR03592 1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKE----DPQKLQQEMMKLYKEEGVNPLGGCLPLLI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 138 QLPVFSIVYYAIRRIDEISASSFLWL-DLGHADPYFILPIAAALATYLQTRVMQTGAegMNGSHAVLSQILSPVMVLSFG 216
Cdd:TIGR03592 77 QMPIFIALYQVLLRSIELRHAPFLWIiDLSSPDPYYILPILMGVTMFLQQKLSPKGP--PDPAQQKMMMYFMPLMFLFFF 154
|
170 180
....*....|....*....|....*
gi 1330666480 217 VFSPSGLVLYWMTGSLFMIFQSLVL 241
Cdd:TIGR03592 155 LSFPAGLVLYWVVSNLFTIIQQLII 179
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
60-243 |
9.18e-56 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 176.89 E-value: 9.18e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 60 GFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKnKDPESQQQyqrEMMELLKENGANPLMGCLPLLVQL 139
Cdd:pfam02096 2 GLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYK-DDRQKLQQ---EMMKLYKKEGVNPLGGCLPMLIQM 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 140 PVFSIVYYAIRRIDEI-SASSFLWL-DLGHADP-----YFILPIAAALATYLQTRVMQTGAeGMNGSHAVLSQILSPVMV 212
Cdd:pfam02096 78 PIFIALYRVLRNSIELrHAPFFLWIaDLSAPDPisilhYYILPILMGVTMFLQQKLTPAPQ-DQPPQMKMMMLYFMPLMF 156
|
170 180 190
....*....|....*....|....*....|.
gi 1330666480 213 LSFGVFSPSGLVLYWMTGSLFMIFQSLVLKK 243
Cdd:pfam02096 157 LFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
1-246 |
8.37e-74 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 225.40 E-value: 8.37e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 1 MLKHKKKLF--FIFVSIFLLAGCDSANVIQSSHTHFLDHYFIYPFSLLILFIGNtWLHQSVGFSIMLVTVGVRMLLAPLN 78
Cdd:PRK01622 1 MLKSYRAVLvsLSLLLVLVLSGCSNAAPIDAHSDGFFDHYFVYPFSFLIQFVAH-HIGGSYGIAIIIVTLIIRSLMIPLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 79 ILQYKNQLSN----KRIQPQLQQLKEKYK-NKDPESQQQYQREMMELLKENGANPL-MGCLPLLVQLPVFSIVYYAIRRI 152
Cdd:PRK01622 80 VSQYKSQRGMqekmAVMKPELDKIQAKLKvTKDLEKQKEYQKEMMELYKSGNINPLaMGCLPLLIQMPILSAFYYAIRRT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 153 DEISASSFLWLDLGHADpyFILPIAAALATYLQTRVMQTGAE-GMNGSHAVLSQILSPVMVLSFGVFSPSGLVLYWMTGS 231
Cdd:PRK01622 160 EEIASHSFLWFNLGHAD--HILPIIAGLTYFIQMKVSQSNGTsPEQVQMLKIQGIMMPAMILFMSFAAPSALVLYWITGG 237
|
250
....*....|....*
gi 1330666480 232 LFMIFQSLVLKKVFQ 246
Cdd:PRK01622 238 LFLMGQTIVLRKVME 252
|
|
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
5-242 |
1.74e-68 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 211.94 E-value: 1.74e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 5 KKKLFFIFVSIFL---LAGCDSANV-IQSSHTHFLDHYFIYPFSLLILFIGNTwLHQSVGFSIMLVTVGVRMLLAPLNIL 80
Cdd:PRK02944 2 KKKLGLLAMVVALmaiLAGCSEVNQpITPKSTGFWNEYFVYPLSQLITYFANL-FGSNYGLAIIVVTLLIRLLILPLMIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 81 QYKNQLSNKRIQPQLQQLKEKYKNKDPESQQQYQREMMELLKENGANPLMGCLPLLVQLPVFSIVYYAIRRIDEISASSF 160
Cdd:PRK02944 81 QTKSTKAMQALQPEMQKLKEKYSSKDQATQQKLQQEMMQLFQKNGVNPLAGCLPIFIQMPILIAFYHAIMRTSEISKHSF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 161 LWLDLGHADPYFILPIAAALATYLQTRVMQTGAEGMNGSHAVLSQILsPVMVLSFGVFSPSGLVLYWMTGSLFMIFQSLV 240
Cdd:PRK02944 161 LWFDLGQADPYYILPIVAGITTFIQQKLMMAGTAGQNPQMAMMLWLM-PIMILIFAINFPAALSLYWVVGNIFMIAQTYL 239
|
..
gi 1330666480 241 LK 242
Cdd:PRK02944 240 IK 241
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
60-243 |
9.87e-63 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 194.52 E-value: 9.87e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 60 GFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNKdpesQQQYQREMMELLKENGANPLMGCLPLLVQL 139
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDD----KQKLQQEMMKLYKEHGVNPLGGCLPLLIQM 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 140 PVFSIVYYAIRRIDEISASSFLW--LDLGHADPYFILPIAAALATYLQTRVMQTGAEGMNGSHAVLsQILSPVMVLSFGV 217
Cdd:cd20070 77 PIFIALYQVLRNSIELRGAPFLWwiLDLSAPDPYYILPILMGVTMFLQQKLTPTPTDDQAPQQKMM-MYFMPVMFTFIFL 155
|
170 180
....*....|....*....|....*.
gi 1330666480 218 FSPSGLVLYWMTGSLFMIFQSLVLKK 243
Cdd:cd20070 156 SFPSGLVLYWLVSNLFSIIQQLIINK 181
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
37-249 |
5.97e-62 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 193.41 E-value: 5.97e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 37 HYFIYPFSLLILFIGNTWLhqSVGFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNkdpeSQQQYQRE 116
Cdd:COG0706 7 GFIAKPLFWLLNFLHSLVG--NWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKD----DPQKLQQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 117 MMELLKENGANPLMGCLPLLVQLPVFSIVYYAIRRIDEISASSFLWL-DLGHADPYFI-LPIAAALATYLQTRVMQTGAe 194
Cdd:COG0706 81 MMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPFLGIpDLSAPDPYYIfLPILMGVTMFLQQKLNPAPA- 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1330666480 195 gMNGSHAVLSQILsPVMVLSFGVFSPSGLVLYWMTGSLFMIFQSLVLKKVFQEKA 249
Cdd:COG0706 160 -QDPQQKKMMYIM-PLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDKKK 212
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
58-241 |
4.85e-60 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 187.69 E-value: 4.85e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 58 SVGFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNkdpeSQQQYQREMMELLKENGANPLMGCLPLLV 137
Cdd:TIGR03592 1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKE----DPQKLQQEMMKLYKEEGVNPLGGCLPLLI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 138 QLPVFSIVYYAIRRIDEISASSFLWL-DLGHADPYFILPIAAALATYLQTRVMQTGAegMNGSHAVLSQILSPVMVLSFG 216
Cdd:TIGR03592 77 QMPIFIALYQVLLRSIELRHAPFLWIiDLSSPDPYYILPILMGVTMFLQQKLSPKGP--PDPAQQKMMMYFMPLMFLFFF 154
|
170 180
....*....|....*....|....*
gi 1330666480 217 VFSPSGLVLYWMTGSLFMIFQSLVL 241
Cdd:TIGR03592 155 LSFPAGLVLYWVVSNLFTIIQQLII 179
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
60-243 |
9.18e-56 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 176.89 E-value: 9.18e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 60 GFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKnKDPESQQQyqrEMMELLKENGANPLMGCLPLLVQL 139
Cdd:pfam02096 2 GLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYK-DDRQKLQQ---EMMKLYKKEGVNPLGGCLPMLIQM 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 140 PVFSIVYYAIRRIDEI-SASSFLWL-DLGHADP-----YFILPIAAALATYLQTRVMQTGAeGMNGSHAVLSQILSPVMV 212
Cdd:pfam02096 78 PIFIALYRVLRNSIELrHAPFFLWIaDLSAPDPisilhYYILPILMGVTMFLQQKLTPAPQ-DQPPQMKMMMLYFMPLMF 156
|
170 180 190
....*....|....*....|....*....|.
gi 1330666480 213 LSFGVFSPSGLVLYWMTGSLFMIFQSLVLKK 243
Cdd:pfam02096 157 LFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
|
|
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
58-254 |
1.41e-48 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 159.91 E-value: 1.41e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 58 SVGFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNkDPESQQQyqrEMMELLKENGANPLMGCLPLLV 137
Cdd:PRK00145 30 SYGIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKYKN-DPQKLQQ---EMMKLYKEKGVNPLGGCLPLLI 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 138 QLPVFSIVYYAIRRIDEISASSFLWL-DLGHADPYFILPIAAALATYLQTRVMQTGaegmNGSHAVLSQILSPVMVLSFG 216
Cdd:PRK00145 106 QWPILIALYYVFNNLTGINGVSFLWIkDLAKPDITWILPILSGATTYLSGYLMTKA----DSSQAGQMKTMNIGMSIFMG 181
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1330666480 217 VFS---PSGLVLYWMTGSLFMIFQSLVLKKVFQEKAVLEAK 254
Cdd:PRK00145 182 VMSwkfKSALVLYWVIGNLIQIIQTYFIKKLELKKKVEAKA 222
|
|
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
1-240 |
1.09e-40 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 141.79 E-value: 1.09e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 1 MLKHKKKLFFIFVS---IFLLAGCDSANViQSSHTHFLDHYFIYPFSLLILFIGNTwLHQSVGFSIMLVTVGVRMLLAPL 77
Cdd:PRK02463 1 MKKTLKRILFSGLAlsmLLTLTGCVGRDK-HGNPTGFIWNFLGAPMSYFIDYFANN-LGLGFGLAIIIVTIIVRLIILPL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 78 NILQ-YKNQL-SNKR--IQPQLQQLKEKYKN-KDPESQQQYQREMMELLKENGANPL--MGCLPLLVQLPVFSIVYYAIR 150
Cdd:PRK02463 79 GLYQsWKATYqSEKMayLKPVFEPINERLKNaTTQEEKMAAQTELMAAQRENGISMLggIGCLPLLIQMPFFSALYFAAQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 151 RIDEISASSFLWLDLGHadPYFILPIAAALATYLQTRV-MQTGAEGMNGSHAVLSqILSPVMVLSFGVFSPSGLVLYWMT 229
Cdd:PRK02463 159 YTKGVSTSTFLGIDLGS--PSLVLTAIIGVLYFFQSWLsMMGVPEEQREQMKAMM-YMMPIMMVVFSFSSPAGVGLYWLV 235
|
250
....*....|.
gi 1330666480 230 GSLFMIFQSLV 240
Cdd:PRK02463 236 GGFFSIIQQLI 246
|
|
| 5TM_YidC_Oxa1_Alb3 |
cd19751 |
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ... |
60-243 |
1.48e-40 |
|
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410992 [Multi-domain] Cd Length: 189 Bit Score: 138.07 E-value: 1.48e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 60 GFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNK--DPESQQQYQREMMELLKENGANPLMGCLPLLV 137
Cdd:cd19751 1 GLSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYKEKasKDKVQQEMQKEMLGLYKKHGVNPMAGCLPLFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 138 QLPVFSIVYYAIRRIDEISASSFLWL-DLGHADPYFILPIAAALATYLQTRV-MQTGAEG--MNGSHAVLSQILsPVMVL 213
Cdd:cd19751 81 QLPIFMAFYFAIMRTEEIRYHTFLWFfDLGQPDYLYILPFVAGITTYFQFKMtMSHQQQMqmMQMQMKVMLYVM-PVMII 159
|
170 180 190
....*....|....*....|....*....|
gi 1330666480 214 SFGVFSPSGLVLYWMTGSLFMIFQSLVLKK 243
Cdd:cd19751 160 IAGLSFPSALSLYWIISNLFMIIQTYFIVR 189
|
|
| 5TM_Oxa1-like |
cd20069 |
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ... |
62-242 |
3.67e-39 |
|
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410993 [Multi-domain] Cd Length: 201 Bit Score: 134.96 E-value: 3.67e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 62 SIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYK----NKDPESQQQYQREMMELLKENGANPLMGCLPLLV 137
Cdd:cd20069 7 TIAATTVALRLLLLPLVIKSQRNAARMANLQPELQKLQEKLKearaSGDQLEAAEARKELKELMKKHNVNPLKSLLLPLV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 138 QLPVFSIVYYAIRRIDEISASSF-----LWL-DLGHADPYFILPIAAALATYLqtrVMQTGAEGMnGSHAVLSQILSPVM 211
Cdd:cd20069 87 QAPVFISFFFALRKMANLPVPSFktgglLWFtDLTVPDPYYILPILTSLTFLA---TIELGAETG-TSGSPQSKTMKNVF 162
|
170 180 190
....*....|....*....|....*....|....*..
gi 1330666480 212 ----VLSFGVFS--PSGLVLYWMTGSLFMIFQSLVLK 242
Cdd:cd20069 163 rglpVLMIPFTAnfPSAVFLYWITSNLFSLAQNLLLR 199
|
|
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
38-254 |
1.03e-38 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 141.16 E-value: 1.03e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 38 YFI-YP-FSLLilfignTWLHQSV---GFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNkDPESQQQ 112
Cdd:PRK01318 303 WFItKPlFWLL------DFLHSFVgnwGWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKYKD-DPQKMQQ 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 113 yqrEMMELLKENGANPLMGCLPLLVQLPVFsivyYAIRR-----IDEISASSFLWL-DLGHADPYFIL-----PIAAALA 181
Cdd:PRK01318 376 ---EMMELYKKEKVNPLGGCLPILIQIPIF----FALYKvllvsIELRHAPFIGWIhDLSAPDPYFILhigllPILMGIT 448
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1330666480 182 TYLQTRVMQTGAEGMNgshavlSQIL--SPVMVLSFGVFSPSGLVLYWMTGSLFMIFQSLVLKKVFQEKAVLEAK 254
Cdd:PRK01318 449 MFLQQKLNPTPTDPMQ------AKIMkfMPLIFTFFFLSFPAGLVLYWIVNNLLTIIQQYLINRRLEKKKLLAAN 517
|
|
| PRK01001 |
PRK01001 |
putative inner membrane protein translocase component YidC; Provisional |
42-248 |
7.67e-27 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234887 [Multi-domain] Cd Length: 795 Bit Score: 108.73 E-value: 7.67e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 42 PFS--LLIL-----FIGNTWlhqsvGFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKnKDPesqQQYQ 114
Cdd:PRK01001 557 PFAalLFIImkffkFLTGSW-----GISIILLTVFLKLLLYPLNAWSIRSMRRMQKLSPYIQEIQQKYK-KEP---KRAQ 627
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 115 REMMELLKENGANPLMGCLPLLVQLPVFSIVYYAIRRIDEISASSFL--WLD-LGHADPYF--------------ILPIA 177
Cdd:PRK01001 628 MEIMALYKTNKVNPITGCLPLLIQLPFLIAMFDLLKSSFLLRGASFIpgWIDnLTAPDVLFswetpiwfignefhLLPIL 707
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1330666480 178 AALATYLQTRVMQTGAEGMNGSHAVLSQILSPVMVLSFGVF---SPSGLVLYWMTGSLFMIFQSLVLKKVFQEK 248
Cdd:PRK01001 708 LGVVMFAQQKISSLKRKGPVTDQQRQQEAMGTMMALLFTFMfynFPSGLNIYWLSSMLLGVIQQWVTNKILDSK 781
|
|
| PRK01315 |
PRK01315 |
putative inner membrane protein translocase component YidC; Provisional |
51-241 |
5.18e-22 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234941 Cd Length: 329 Bit Score: 92.88 E-value: 5.18e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 51 GNTWlhqsvGFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNKdpesQQQYQREMMELLKENGANPLM 130
Cdd:PRK01315 39 GLTW-----VLSIVGLVIVIRALLIPLFVKQIKSQRNMQEIQPKMKKIQEKYKGD----RERMSQEMMKLYKETGTNPLS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 131 GCLPLLVQLPVFSIVY----YAIRRIDEISA-SSFLWLDLGHADpYFILPIAAALAT----------------------- 182
Cdd:PRK01315 110 SCLPLLLQMPIFFALYrvldSAASRGDGIGPiNPPLLESFRHAH-IFGAPLAATFLQalnagntavqvvaavliilmsas 188
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1330666480 183 --YLQTRVMQ--TGAEGMNGSHAVLSQILS---PVMVLSFGVFSPSGLVLYWMTGSLFMIFQSLVL 241
Cdd:PRK01315 189 qfITQLQLMTknMPPEAKTGPMAQQQKMLLylfPLMFLVSGIAFPVGVLFYWLTSNVWTMGQQFYV 254
|
|
| PRK03449 |
PRK03449 |
putative inner membrane protein translocase component YidC; Provisional |
39-254 |
7.64e-22 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 179580 Cd Length: 304 Bit Score: 92.05 E-value: 7.64e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 39 FIY-PFSLLILFigntWlHQSVGF------------SIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNk 105
Cdd:PRK03449 4 FIYyPVSAILWF----W-HKLFSFvlgpdngfawalSVMFLVFTLRALLYKPFVRQIRTTRKMQELQPQIKALQKKYGN- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 106 dpeSQQQYQREMMELLKENGANPLMGCLPLLVQLPVFSIVYYAIRRIDEISAS-------------------------SF 160
Cdd:PRK03449 78 ---DRQKMALEMQKLQKEHGFNPILGCLPMLAQIPVFLGLFHVLRSFNRTGTGfgqlgmsveenrntpnyvfsaedvqSF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 161 LWLDLGHA--DPYFILP-----------------------IAAALATYLQTRVM---QTGAEGMNGSHAVLSQI---LSP 209
Cdd:PRK03449 155 LDARLFGAplSAYITMPrsgldafvdftrtniilvgvplmIIAGVATHFNSRASvarQSAEAAANPQTAMMNKLalwVFP 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1330666480 210 VMVLSFGVFSPSGLVLYWMTGSLFMIFQS-LVLKKVFQE-----KAVLEAK 254
Cdd:PRK03449 235 LGVLVGGPFLPLAILLYWVSNNIWTFGQQhYVFGKIDKEeeakkQAKAERR 285
|
|
| PRK00247 |
PRK00247 |
putative inner membrane protein translocase component YidC; Validated |
39-248 |
1.88e-20 |
|
putative inner membrane protein translocase component YidC; Validated
Pssm-ID: 178945 [Multi-domain] Cd Length: 429 Bit Score: 89.52 E-value: 1.88e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 39 FIYPFSLLIlfigNTW---LHQSVG--------FSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKNK-D 106
Cdd:PRK00247 5 FIYPVSGVM----KLWhllLHNVLGlddslawfASLFGLVITVRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKGKtD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 107 PESQQQYQREMMELLKENGANPLMGCLPLLVQLPVFSIVYYAIRRI--------------------DEI----------- 155
Cdd:PRK00247 81 EASIRELQQKQKDLNKEYGYNPLAGCVPALIQIPVFLGLYQVLLRMarpegglenpvhqpigfltsEEVesflqgrvfnv 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 156 --------SASSFLWLDLGHADPY-FILP--IAAALAT-----YLQTRVMQTG------AEGMNGSHAVLSqILSPVMVL 213
Cdd:PRK00247 161 plpayvsmPAEQLAYLGTTQATVLaFVLPlfIAAAVFTainmaMSTYRSFQTNdhdsgfAVGMLKFLIVMA-ILAPIFPL 239
|
250 260 270
....*....|....*....|....*....|....*..
gi 1330666480 214 SFGVFS--PSGLVLYWMTGSLFMIFQSLVLKKVFQEK 248
Cdd:PRK00247 240 SLGLTGpfPTAIALYWVANNLWTLIQNIIMYLILERK 276
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
39-239 |
8.66e-18 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 81.21 E-value: 8.66e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 39 FIYPFSLLILFI-----GNTWLHQSVGFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQLKEKYKN--KDPESQQ 111
Cdd:PRK02201 108 FVYPIAQIILSImasqsLSELYGWSTILAIIVVVLIIRLISFLITFKSTFNQEKQEELQGKKAKIDAKYKDykKDKQMKQ 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 112 QYQREMMELLKENGANPLMGCLPLLVQLPVFSIVYYAIRRIDEISASSFLWLDLGhADPY-----------FILPIAAA- 179
Cdd:PRK02201 188 RKQQEIQELYKKHNISPFSPFVQMFVTLPIFIAVYRVVQSLPSIKVTTWLGIDLS-ATSWqeifagnwiylPILIIVVPv 266
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1330666480 180 ------LATYLQTRVMQTGAEGMNGSHAVLSQ-----ILSPVMVLsFGVFSPSGLVLYWMTGSLFMIFQSL 239
Cdd:PRK02201 267 qalsqlLPQILNKKKNKERTLNVKEKEALKKQnktqnIISIVFIF-FGVIFAAGVQIYWIIGGIWTILQTL 336
|
|
| PRK02654 |
PRK02654 |
putative inner membrane protein translocase component YidC; Provisional |
58-141 |
1.51e-16 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235058 Cd Length: 375 Bit Score: 78.10 E-value: 1.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1330666480 58 SVGFSIMLVTVGVRMLLAPLNILQYKNQLSNKRIQPQLQQ----LKEKYKNkDPESQQQyqrEMMELLKENGaNPLMGCL 133
Cdd:PRK02654 26 SYGLAIVALTLVIRFALYPLSAGSIRNMRRMKIAQPVMQKrqaeIQERYKN-DPQKQQE---EMGKLMKEFG-NPLAGCL 100
|
....*...
gi 1330666480 134 PLLVQLPV 141
Cdd:PRK02654 101 PLLVQMPI 108
|
|
| |
