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Conserved domains on  [gi|1331829191|gb|PNI88512|]
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NBPF20 isoform 4 [Pan troglodytes]

Protein Classification

NBPF family protein( domain architecture ID 10535968)

neuroblastoma breakpoint family (NBPF) protein is a DUF1220 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 340-407 1.37e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.86  E-value: 1.37e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1331829191 340 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQAYGSSFYALEEKHVGFSL 407
Cdd:pfam06758   1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 265-332 2.52e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 2.52e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1331829191 265 YQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 332
Cdd:pfam06758   1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 105-168 4.76e-15

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 69.76  E-value: 4.76e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1331829191 105 EEAEKVQKSSPP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKFTFEEDKVDSTL 168
Cdd:pfam06758   2 EEEEEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 444-497 1.63e-14

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 68.22  E-value: 1.63e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1331829191 444 LNGVLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFAL 497
Cdd:pfam06758  15 LSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 197-256 4.11e-14

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


:

Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 67.06  E-value: 4.11e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191 197 KGPVSPRLSRELLDDKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 256
Cdd:pfam06758   8 QEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSA 67
PTZ00121 super family cl31754
MAEBL; Provisional
 4-130 9.81e-05

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 9.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191    4 NEQRQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAARSLNEHLQALLTPDEPDKSQGQDLQEQLAEG 83
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEE 1604

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1331829191   84 CRLAQQLVQKLSPENDEDVQVEEAEKVQKSSPPREMQKAEEKEVPED 130
Cdd:PTZ00121  1605 KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE 1651
 
Name Accession Description Interval E-value
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 340-407 1.37e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.86  E-value: 1.37e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1331829191 340 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQAYGSSFYALEEKHVGFSL 407
Cdd:pfam06758   1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 265-332 2.52e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 2.52e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1331829191 265 YQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 332
Cdd:pfam06758   1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 105-168 4.76e-15

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 69.76  E-value: 4.76e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1331829191 105 EEAEKVQKSSPP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKFTFEEDKVDSTL 168
Cdd:pfam06758   2 EEEEEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 444-497 1.63e-14

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 68.22  E-value: 1.63e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1331829191 444 LNGVLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFAL 497
Cdd:pfam06758  15 LSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 197-256 4.11e-14

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 67.06  E-value: 4.11e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191 197 KGPVSPRLSRELLDDKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 256
Cdd:pfam06758   8 QEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSA 67
PTZ00121 PTZ00121
MAEBL; Provisional
 4-130 9.81e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 9.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191    4 NEQRQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAARSLNEHLQALLTPDEPDKSQGQDLQEQLAEG 83
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEE 1604

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1331829191   84 CRLAQQLVQKLSPENDEDVQVEEAEKVQKSSPPREMQKAEEKEVPED 130
Cdd:PTZ00121  1605 KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE 1651
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 4-168 1.26e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.57  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191    4 NEQRQFKEEKLAEQLKQAEELRQykvLVHSQERELTQLKEKLREGRDAARSLNEHLQalltpdepdksQGQDLQEQLAEG 83
Cdd:TIGR00606  828 NQEKQEKQHELDTVVSKIELNRK---LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQ-----------RRQQFEEQLVEL 893

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191   84 CRLAQQLVQKLSPENDEDVQVEEA-EKVQKSSPPREMQKAEEKEVPEDSLEECAITCSNSHGpydsnqpHRKTKFTFEED 162
Cdd:TIGR00606  894 STEVQSLIREIKDAKEQDSPLETFlEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHG-------YMKDIENKIQD 966


                   ....*.
gi 1331829191  163 KVDSTL 168
Cdd:TIGR00606  967 GKDDYL 972
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
5-125 5.91e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.12  E-value: 5.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191   5 EQRQFKEEKLAEQLKQA-EELRQYKVLVHSQERELTQLKEKLREGRDAARSLNEHLQALLTPDEPDKSQGQDLQEQLAEg 83
Cdd:COG4372    34 RKALFELDKLQEELEQLrEELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEE- 112

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1331829191  84 crlAQQLVQKLSPENDEDVQVEEAEKVQKSSPPREMQKAEEK 125
Cdd:COG4372   113 ---LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEE 151
 
Name Accession Description Interval E-value
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 340-407 1.37e-19

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 82.86  E-value: 1.37e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1331829191 340 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQAYGSSFYALEEKHVGFSL 407
Cdd:pfam06758   1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 265-332 2.52e-17

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 76.31  E-value: 2.52e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1331829191 265 YQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 332
Cdd:pfam06758   1 DEEEEEDQEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 105-168 4.76e-15

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 69.76  E-value: 4.76e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1331829191 105 EEAEKVQKSSPP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKFTFEEDKVDSTL 168
Cdd:pfam06758   2 EEEEEDQEPLAPrlsRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 444-497 1.63e-14

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 68.22  E-value: 1.63e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1331829191 444 LNGVLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFAL 497
Cdd:pfam06758  15 LSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSAL 68
Olduvai pfam06758
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ...
 197-256 4.11e-14

Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.


Pssm-ID: 429104 [Multi-domain]  Cd Length: 68  Bit Score: 67.06  E-value: 4.11e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191 197 KGPVSPRLSRELLDDKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 256
Cdd:pfam06758   8 QEPLAPRLSRELPEVEEQEVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSSA 67
PTZ00121 PTZ00121
MAEBL; Provisional
 4-130 9.81e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 9.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191    4 NEQRQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAARSLNEHLQALLTPDEPDKSQGQDLQEQLAEG 83
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEE 1604

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1331829191   84 CRLAQQLVQKLSPENDEDVQVEEAEKVQKSSPPREMQKAEEKEVPED 130
Cdd:PTZ00121  1605 KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE 1651
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 4-168 1.26e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.57  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191    4 NEQRQFKEEKLAEQLKQAEELRQykvLVHSQERELTQLKEKLREGRDAARSLNEHLQalltpdepdksQGQDLQEQLAEG 83
Cdd:TIGR00606  828 NQEKQEKQHELDTVVSKIELNRK---LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQ-----------RRQQFEEQLVEL 893

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191   84 CRLAQQLVQKLSPENDEDVQVEEA-EKVQKSSPPREMQKAEEKEVPEDSLEECAITCSNSHGpydsnqpHRKTKFTFEED 162
Cdd:TIGR00606  894 STEVQSLIREIKDAKEQDSPLETFlEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHG-------YMKDIENKIQD 966


                   ....*.
gi 1331829191  163 KVDSTL 168
Cdd:TIGR00606  967 GKDDYL 972
PTZ00121 PTZ00121
MAEBL; Provisional
 5-130 1.98e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 1.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191    5 EQRQFKEEKLAEQLKQAEElrQYKVLVHSQERELTQLKEKLREGRDAARSLNEHLQALLTPDEpDKSQGQDLQEQLAEGC 84
Cdd:PTZ00121  1639 KKKEAEEKKKAEELKKAEE--ENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE-EAKKAEELKKKEAEEK 1715

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1331829191   85 RLAQQLVQKlspENDEDVQVEEAEKVQKssppREMQKAEEKEVPED 130
Cdd:PTZ00121  1716 KKAEELKKA---EEENKIKAEEAKKEAE----EDKKKAEEAKKDEE 1754
PTZ00121 PTZ00121
MAEBL; Provisional
 3-130 2.41e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 2.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191    3 RNEQRQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKE--KLREGRDAARSL------NEHLQALLTPDEPDKSQGQ 74
Cdd:PTZ00121  1571 KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEakKAEEAKIKAEELkkaeeeKKKVEQLKKKEAEEKKKAE 1650

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1331829191   75 DLQEQLAEGCRLAQQLVQKLSPENDEDVQVEEAEKVQKSSPPREMQKAEEKEVPED 130
Cdd:PTZ00121  1651 ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE 1706
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 5-108 2.99e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 2.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191    5 EQRQFKEEKLAEQLKQAEELR-QYKVLVHSQERELTQLKEKLREG-------RDAARSLNEHLQALLTPDEPDKSQGQDL 76
Cdd:TIGR02168  862 EELEELIEELESELEALLNERaSLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNL 941

                           90       100       110
                   ....*....|....*....|....*....|..
gi 1331829191   77 QEQLAEGCRLAQQLVQKLSPENDEDVQVEEAE 108
Cdd:TIGR02168  942 QERLSEEYSLTLEEAEALENKIEDDEEEARRR 973
PTZ00121 PTZ00121
MAEBL; Provisional
 12-130 3.89e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 3.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191   12 EKLAEQLKQAEELRQYKvlvhSQERELTQLKEKLREGRDAARSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLV 91
Cdd:PTZ00121  1424 KKKAEEKKKADEAKKKA----EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKA 1499

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1331829191   92 QKLSPENDEDVQVEEAEKVQKSSPPREMQKAEEKEVPED 130
Cdd:PTZ00121  1500 DEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE 1538
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 19-126 5.89e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 39.23  E-value: 5.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191  19 KQAEELRQYKVLVHSQERELTQLKEKLREGRDAARSLNEHLQALLTPDEPDKSQGQDLQEQLAEgcrlAQQLVQKLSPEN 98
Cdd:TIGR04523 304 KEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE----KQNEIEKLKKEN 379

                          90       100
                  ....*....|....*....|....*...
gi 1331829191  99 DEDVQVEEAEKVQKSSPPREMQKAEEKE 126
Cdd:TIGR04523 380 QSYKQEIKNLESQINDLESKIQNQEKLN 407
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
5-125 5.91e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.12  E-value: 5.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191   5 EQRQFKEEKLAEQLKQA-EELRQYKVLVHSQERELTQLKEKLREGRDAARSLNEHLQALLTPDEPDKSQGQDLQEQLAEg 83
Cdd:COG4372    34 RKALFELDKLQEELEQLrEELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEE- 112

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1331829191  84 crlAQQLVQKLSPENDEDVQVEEAEKVQKSSPPREMQKAEEK 125
Cdd:COG4372   113 ---LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEE 151
PTZ00121 PTZ00121
MAEBL; Provisional
 5-134 9.68e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.97  E-value: 9.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331829191    5 EQRQFKE-EKLAEQLKQAEELRQYKvlvhSQERELTQLKEKLREGRDAARSLNEHLQALLTPDEPDKSQgqdlQEQLAEG 83
Cdd:PTZ00121  1455 EAKKAEEaKKKAEEAKKADEAKKKA----EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE----EAKKADE 1526

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1331829191   84 CRLAQQlvqklSPENDEDVQVEEAEKVQKSSPPREMQKAEEKEVPEDSLEE 134
Cdd:PTZ00121  1527 AKKAEE-----AKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA 1572
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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