|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-1049 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 2118.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 1 MAKFFIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSS 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 81 TSDSSGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVLGLINTDGSMKQEDIADYAGA 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 161 NIKDPISRTTGVGDVQLFGSQYAMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 241 TSADEFSKILLKVNQDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPSG 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 321 LKVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMVL 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 481 SVIVALILTPALCATMLKPVAKGDHGEGKKGFFGWFNRMFDKSTHHYTDSVGNILRSTGRYLLLYLLIVVAMAFLFIRLP 560
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 561 SSFLPDEDQGVFLTMAQLPAGATQERTQKVLDEVTDYYLTQEKDNVNSVFTVNGFGFSGRGQNTGLAFVSLKNWDERPGA 640
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 641 ENKVPAITGRAMGRFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQGNLGHDKLTQARNQLLGEAAQHPDLLSQVRPNG 720
Cdd:PRK15127 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDMLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLASAWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNWYVRGTNGQMVP 800
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 801 FSAFSTSHWEYGSPRLERYNGLPSMQIQGQAVQGKSTGEAMAMMEQLASKLPTGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:PRK15127 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQERLSGNQAPALYAIS 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGL 960
Cdd:PRK15127 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATILAIFFVPVFFVVVRRRFSRKSEDI 1040
Cdd:PRK15127 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
|
....*....
gi 1349323678 1041 EHSHPVEHH 1049
Cdd:PRK15127 1041 EHSHTVDHH 1049
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1044 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1875.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 1 MAKFFIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSS 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 81 TSDSSGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVLGLINTDGSMKQEDIADYAGA 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 161 NIKDPISRTTGVGDVQLFGSQYAMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 241 TSADEFSKILLKVNQDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPSG 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 321 LKVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMVL 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 481 SVIVALILTPALCATMLKPVAKGDHGEGKKGFFGWFNRMFDKSTHHYTDSVGNILRSTGRYLLLYLLIVVAMAFLFIRLP 560
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 561 SSFLPDEDQGVFLTMAQLPAGATQERTQKVLDEVTDYYLTQEKDNVNSVFTVNGFGFSGRGQNTGLAFVSLKNWDERPGA 640
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 641 ENKVPAITGRAMGRFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQGNLGHDKLTQARNQLLGEAAQHPDlLSQVRPNG 720
Cdd:TIGR00915 641 ENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPA-LTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLASAWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNWYVRGTNGQMVP 800
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVP 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 801 FSAFSTSHWEYGSPRLERYNGLPSMQIQGQAVQGKSTGEAMAMMEQLASKLPTGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:TIGR00915 800 FSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALS 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKeGKGL 960
Cdd:TIGR00915 880 LLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQ-GKSI 958
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATILAIFFVPVFFVVVRRRFSRKSEDI 1040
Cdd:TIGR00915 959 VEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEK 1038
|
....
gi 1349323678 1041 EHSH 1044
Cdd:TIGR00915 1039 EMSV 1042
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
1-1019 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 1611.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 1 MAKFFIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSS 80
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 81 TSDSSGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVLGLINTDGSMKQEDIADYAGA 160
Cdd:PRK10555 81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 161 NIKDPISRTTGVGDVQLFGSQYAMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK10555 161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 241 TSADEFSKILLKVNQDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPSG 320
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 321 LKVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVL 400
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMVL 480
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 481 SVIVALILTPALCATMLKPVAKGDHgEGKKGFFGWFNRMFDKSTHHYTDSVGNILRSTGRYLLLYLLIVVAMAFLFIRLP 560
Cdd:PRK10555 481 SVLVAMILTPALCATLLKPLKKGEH-HGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLP 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 561 SSFLPDEDQGVFLTMAQLPAGATQERTQKVLDEVTDYYLTQEKDNVNSVFTVNGFGFSGRGQNTGLAFVSLKNWDERPGA 640
Cdd:PRK10555 560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSK 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 641 ENKVPAITGRAMGRFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQGNLGHDKLTQARNQLLGEAAQHPdLLSQVRPNG 720
Cdd:PRK10555 640 TGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNP-ELTRVRHNG 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLASAWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNWYVRGTNGQMVP 800
Cdd:PRK10555 719 LDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 801 FSAFSTSHWEYGSPRLERYNGLPSMQIQGQAVQGKSTGEAMAMMEQLASKLPTGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:PRK10555 799 FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAIS 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKeGKGL 960
Cdd:PRK10555 879 LLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQK-GHDL 957
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 1349323678 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATILAI 1019
Cdd:PRK10555 958 FEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAI 1016
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1019 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1449.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 1 MAKFFIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 81 TSdSSGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVLGLINTDGSMKQEDIADYAGA 160
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 161 NIKDPISRTTGVGDVQLFG-SQYAMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLggtppvKGQQLNASIIAQTR 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 240 LTSADEFSKILLKvNQDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPS 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 320 GLKVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 400 LAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMV 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 480 LSVIVALILTPALCATMLKPVAKGDHGegkkGFFGWFNRMFDKSTHHYTDSVGNILRSTGRYLLLYLLIVVAMAFLFIRL 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHG----GFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 560 PSSFLPDEDQGVFLTMAQLPAGATQERTQKVLDEVTDYYLtqEKDNVNSVFTVNGFGFSG--RGQNTGLAFVSLKNWDER 637
Cdd:pfam00873 549 PTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILK--EKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKER 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 638 PGAENKVPAITGRAMGRFSQIKDAMVFAFNLPAIVELGTATGFDFELID-QGNLGHDKLTQARNQLLGEAAQHPDlLSQV 716
Cdd:pfam00873 627 PGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG-LSDV 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 717 RPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLASAWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNWYVRGTNG 796
Cdd:pfam00873 706 RSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYG 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 797 QMVPFSAFSTSHWEYGSPRLERYNGLPSMQIQGQAVQGKSTGEAMAMMEQLASK--LPTGIGYDWTGMSYQERLSGNQAP 874
Cdd:pfam00873 786 KMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLP 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 875 ALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLME 954
Cdd:pfam00873 866 ILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELRE 945
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1349323678 955 KEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATILAI 1019
Cdd:pfam00873 946 QEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTL 1010
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-1019 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 1240.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 1 MAKFFIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSS 80
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 81 TSdSSGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVLGLINTDGSMKQEDIADYAGA 160
Cdd:PRK09577 81 TS-SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 161 NIKDPISRTTGVGDVQLFGSQYAMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 241 TSADEFSKILLKVNQDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPSG 320
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 321 LKVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVL 400
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMVL 480
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 481 SVIVALILTPALCATMLKPVAkGDHgEGKKGFFGWFNRMFDKSTHHYTDSVGNILRSTGRYLLLYLLIVVAMAFLFIRLP 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVD-GDH-HEKRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLP 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 561 SSFLPDEDQGVFLTMAQLPAGATQERTQKVLDEVTDYylTQEKDNVNSVFTVNGFGFSGRGQNTGLAFVSLKNWDERPGA 640
Cdd:PRK09577 558 TAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESY--LRRHEPVAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAA 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 641 ENKVPAITGRAMGRFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQGNLGHDKLTQARNQLLGEAAQHPdLLSQVRPNG 720
Cdd:PRK09577 636 RDHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDP-ALTDLMFAG 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLASAWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNWYVRGTNGQMVP 800
Cdd:PRK09577 715 TQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVP 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 801 FSAFSTSHWEYGSPRLERYNGLPSMQIQGQAVQGKSTGEAMAMMEQLASKLPTGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:PRK09577 795 LAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERLSGAQAPMLFALS 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEkEGKGL 960
Cdd:PRK09577 875 VLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVA-QRMSL 953
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 1349323678 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATILAI 1019
Cdd:PRK09577 954 ADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAV 1012
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1019 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1237.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 1 MAKFFIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSS 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 81 TSdSSGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVLGLINTDgsMKQEDIADYAGA 160
Cdd:COG0841 83 TS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 161 NIKDPISRTTGVGDVQLFGS-QYAMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGtppvkgQQLNASIIAQTR 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 240 LTSADEFSKILLKVNqDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPS 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 320 GLKVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMV 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 480 LSVIVALILTPALCATMLKPvakgDHGEGKKGFFGWFNRMFDKSTHHYTDSVGNILRSTGRYLLLYLLIVVAMAFLFIRL 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLKP----HPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 560 PSSFLPDEDQGVFLTMAQLPAGATQERTQKVLDEVTDYYLtqEKDNVNSVFTVNGFGFSGRGQNTGLAFVSLKNWDERPg 639
Cdd:COG0841 548 PTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILL--EVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERD- 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 640 aeNKVPAITGRAMGRFSQIKDAMVFAFNLPAIvELGTATGFDFELidQGNlGHDKLTQARNQLLGEAAQHPdLLSQVRPN 719
Cdd:COG0841 625 --RSADEIIARLREKLAKIPGARVFVFQPPAG-GLGSGAPIEVQL--QGD-DLEELAAAAEKLLAALRQIP-GLVDVRSD 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 720 GLEDTPQFKIDIDQEKAQALGVSISDINTTLASAWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNWYVRGTNGQMV 799
Cdd:COG0841 698 LQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMV 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 800 PFSAFSTSHWEYGSPRLERYNGLPSMQIQGQAVQGKSTGEAMAMMEQLASK--LPTGIGYDWTGMSYQERLSGNQAPALY 877
Cdd:COG0841 778 PLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAF 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 878 AISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEkEG 957
Cdd:COG0841 858 LLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLRE-EG 936
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1349323678 958 KGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATILAI 1019
Cdd:COG0841 937 MSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTL 998
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1017 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 759.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 5 FIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSSTSdS 84
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS-S 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 85 SGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVE-KSSSSFLMVLGLinTDGSMKQEDIADYAGANIK 163
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKaNSADTPIMYIGL--TSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 164 DPISRTTGVGDVQLFGSQY-AMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTS 242
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGA------VRGDSVVSTVRANDQLKT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 243 ADEFSKILLKVNQDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPSGLK 322
Cdd:NF033617 235 AEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 323 VVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAI 402
Cdd:NF033617 315 VNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMVLSV 482
Cdd:NF033617 395 GLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISG 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 483 IVALILTPALCATMLKPVAKGDhgegkkGFFGWFNRMFDKSTHHYTDSVGNILRSTgRYLLLYLLIVVAMAF-LFIRLPS 561
Cdd:NF033617 474 IVALTLTPMMCSRLLKANEKPG------RFARAVDRFFDGLTARYGRGLKWVLKHR-PLTLVVALATLALLPlLYVFIPK 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 562 SFLPDEDQGVFLTMAQLPAGATQERTQKVLDEVTDYYLTQEKdnVNSVFTVNGFGfSGRGQNTGLAFVSLKNWDERpgaE 641
Cdd:NF033617 547 ELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPE--VQSLTSFNGVG-GNPGDNTGFGIINLKPWDER---D 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 642 NKVPAITGRAMGRFSQIKDAMVFAFNLPAIvELGTATGFDFELIDQGNLGHDKLTQARNQLLGEAAQHPdLLSQVRPNGL 721
Cdd:NF033617 621 VSAQEIIDRLRPKLAKVPGMDLFLFPLQDL-PGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSP-QFADVDSDLQ 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 722 EDTPQFKIDIDQEKAQALGVSISDINTTLASAWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNWYVRGTNGQMVPF 801
Cdd:NF033617 699 DKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPL 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 802 SAFSTSHWEYGSPRLERYNGLPSMQIQGQAVQGKSTGEAMAMMEQLA-SKLPTGIGYDWTGMSYQERLSGNQAPALYAIS 880
Cdd:NF033617 779 STLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAkELLPSGISGSFQGAARAFQEEGSSLLFLFLLA 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGL 960
Cdd:NF033617 859 LAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSR 938
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*..
gi 1349323678 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATIL 1017
Cdd:NF033617 939 REAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLF 995
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
5-1019 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 597.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 5 FIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSSTSDS 84
Cdd:PRK09579 7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 85 SGTVqITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVLGLinTDGSMKQEDIADYAGANIKD 164
Cdd:PRK09579 87 NFSI-ISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISF--YSEEMSNPQITDYLSRVIQP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 165 PISRTTGVGDVQLFGSQ-YAMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTSA 243
Cdd:PRK09579 164 KLATLPGMAEAEILGNQvFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGE------VKGEYVVTSINASTELKSA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 244 DEFSKILLKVNQDgSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPSGLKV 323
Cdd:PRK09579 238 EAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 324 VYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIG 403
Cdd:PRK09579 317 SIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 404 LLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMVLSVI 483
Cdd:PRK09579 397 LVVDDAIVVVENIHRHI-EEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGI 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 484 VALILTPALCATMLKpvakgdHGEGKKGFFGWFNRMFDKSTHHYTDSVGNILRSTGRYLLLYLLIVVAMAFLFIRLPSSF 563
Cdd:PRK09579 476 VALTLSPMMCALLLR------HEENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 564 LPDEDQGVFLTMAQLPAGATQERTQKVLDEVTDYYltQEKDNVNSVFTVNGFGfsgrGQNTGLAFVSLKNWDERPGAENK 643
Cdd:PRK09579 550 APEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIF--KSFPEYYSSFQINGFN----GVQSGIGGFLLKPWNERERTQME 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 644 V-PAItgraMGRFSQIKDAMVFAFNLPAIVelGTATGFDFELIDQGNLGHDKLTQARNQlLGEAAQHPDLLSQVRPNGLE 722
Cdd:PRK09579 624 LlPLV----QAKLEEIPGLQIFGFNLPSLP--GTGEGLPFQFVINTANDYESLLQVAQR-VKQRAQESGKFAFLDIDLAF 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 723 DTPQFKIDIDQEKAQALGVSISDINTTLASAWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNWYVRGTNGQMVPFS 802
Cdd:PRK09579 697 DKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLS 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 803 AFSTSHWEYGSPRLERYNGLPSMQIQGQAVQgkSTGEAMAMMEQLA-SKLPTGIGYDWTGMSYQERLSGNQAPALYAISL 881
Cdd:PRK09579 777 TLITLSDRARPRQLNQFQQLNSAIISGFPIV--SMGEAIETVQQIArEEAPEGFAFDYAGASRQYVQEGSALWVTFGLAL 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 882 IVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGLI 961
Cdd:PRK09579 855 AIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLSRR 934
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*...
gi 1349323678 962 EATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATILAI 1019
Cdd:PRK09579 935 EAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTL 992
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
3-1017 |
6.56e-133 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 427.91 E-value: 6.56e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 3 KFFIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSSTS 82
Cdd:COG3696 7 RFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 83 dSSGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQ-G-VSvekSSSSFLMVLGLINTDGSMKQED---IADY 157
Cdd:COG3696 87 -RFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPElGpIS---TGLGEIYQYTLESDPGKYSLMElrtLQDW 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 158 agaNIKDPISRTTGVGDVQLFG---SQYamRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLggtpPVKGQQLNasI 234
Cdd:COG3696 163 ---VIRPQLRSVPGVAEVNSFGgfvKQY--QVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYI----ERGGQEYL--V 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 235 IAQTRLTSADEFSKILLKvNQDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLA-TGANALDTAEAVRKTIAGL 313
Cdd:COG3696 232 RGIGLIRSLEDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMlKGENALEVIEAVKAKLAEL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 314 EPFFPSGLKVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTL 393
Cdd:COG3696 311 KPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLM 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 394 TMFGMVLAIGLLVDDAIVVVENVERVMAE-----EGLPPKEATRKSMGQIQGALV-GIALVLsAVFIPMAFFGGSTGAIY 467
Cdd:COG3696 391 SLGGLAIDFGIIVDGAVVMVENILRRLEEnraagTPRERLEVVLEAAREVRRPIFfATLIII-LVFLPIFTLEGVEGKLF 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 468 RQFSITIVSAMVLSVIVALILTPALCATMLKPvaKGDHGEgkkgffgwfNRMFDKSTHHYTDSVGNILRSTGRYLLLYLL 547
Cdd:COG3696 470 RPMALTVIFALLGALLLSLTLVPVLASLLLRG--KVPEKE---------NPLVRWLKRLYRPLLRWALRHPKLVLAVALV 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 548 IVVAMAFLFIRLPSSFLPDEDQGVFLTMAQLPAG-------ATQERTQKVLDEVtdyyltqekDNVNSVftvngFGFSGR 620
Cdd:COG3696 539 LLVLALALFPRLGSEFLPELDEGDLLVMATLPPGisleesvELGQQVERILKSF---------PEVESV-----VSRTGR 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 621 --------GQNTGLAFVSLKNWDERPGAENKvPAITGRAMGRFSQIKdAMVFAFNLP---AIVEL--GTAT-------GF 680
Cdd:COG3696 605 aedatdpmGVNMSETFVILKPRSEWRSGRTK-EELIAEMREALEQIP-GVNFNFSQPiqmRVDELlsGVRAdvavkifGD 682
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 681 DFELIDQgnlghdkltqarnqlLGEAAQhpDLLSQVRpnGLED--------TPQFKIDIDQEKAQALGVSISDINTTLAS 752
Cdd:COG3696 683 DLDVLRR---------------LAEQIE--AVLKTVP--GAADvqvervtgLPQLDIRIDRDAAARYGLNVADVQDVVET 743
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 753 AWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNWYVRGTNGQMVPFSAFSTSHWEYGSPRLERYNGLPSMQIQ---- 828
Cdd:COG3696 744 AIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVQanvr 823
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 829 ----GQAVQgkstgEAMAMMEQlASKLPTGIGYDWTGM-----SYQERLSgnqapALYAISLIVVFLCLAALYESWSIPF 899
Cdd:COG3696 824 grdlGSFVA-----EAQAKVAE-QVKLPPGYYIEWGGQfenlqRATARLA-----IVVPLALLLIFLLLYLAFGSVRDAL 892
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 900 SVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEkEGKGLIEATLEAVRMRLRPILMTS 979
Cdd:COG3696 893 LILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRA-EGLDLREAIIEGALERLRPVLMTA 971
|
1050 1060 1070
....*....|....*....|....*....|....*...
gi 1349323678 980 LAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATIL 1017
Cdd:COG3696 972 LVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLL 1009
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
5-1017 |
2.06e-120 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 394.48 E-value: 2.06e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 5 FIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSSTSdS 84
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSS-S 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 85 SGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGvSVEKS--SSSFLMVLGLinTDGSMKQEDIADYAGANI 162
Cdd:PRK10614 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKAnpSDAPIMILTL--TSDTYSQGQLYDFASTQL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 163 KDPISRTTGVGDVQLFGSQY-AMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLT 241
Cdd:PRK10614 163 AQTISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGA------VEDGTHRWQIQTNDELK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 242 SADEFSKILLKVNQdGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPSGL 321
Cdd:PRK10614 237 TAAEYQPLIIHYNN-GAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 322 KVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLA 401
Cdd:PRK10614 316 DLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIA 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 402 IGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMVLS 481
Cdd:PRK10614 396 TGFVVDDAIVVLENISRHL-EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGIS 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 482 VIVALILTPALCATMLKPVAKGDHGEgKKGFfgwfNRMFDKSTHHYTDSVGNILRSTGRYLLLYLLIVVAMAFLFIRLPS 561
Cdd:PRK10614 475 LLVSLTLTPMMCAWLLKSSKPREQKR-LRGF----GRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 562 SFLPDEDQGVFLTMAQlpagATQERT-QKVLDEVTDYYLTQEKDNvnSVFTVNGFGFSGRgQNTGLAFVSLKNWDERPGA 640
Cdd:PRK10614 550 TFFPEQDTGRLMGFIQ----ADQSISfQAMRGKLQDFMKIIRDDP--AVDNVTGFTGGSR-VNSGMMFITLKPLSERSET 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 641 ENKVPAitgRAMGRFSQIKDAMVFafnLPAIVEL-----GTATGFDFELIDqgnlghDKLTQARN------QLLGEAAQH 709
Cdd:PRK10614 623 AQQVID---RLRVKLAKEPGANLF---LMAVQDIrvggrQSNASYQYTLLS------DDLAALREwepkirKALAALPEL 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 710 PDLLSQVRPNGLEdtpqFKIDIDQEKAQALGVSISDINTTLASAWGGSYVNDFIDRGRVKKVYVMSQAQYRMLPGDINNW 789
Cdd:PRK10614 691 ADVNSDQQDKGAE----MALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKM 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 790 YVRGTNGQMVPFSAFStsHWE-YGSPRLERYNGLP-SMQIQGQAVQGKSTGEAMAMMEQLASKL--PTGI--GYDWTGMS 863
Cdd:PRK10614 767 FVINNEGKAIPLSYFA--KWQpANAPLSVNHQGLSaASTISFNLPTGKSLSDASAAIERAMTQLgvPSTVrgSFAGTAQV 844
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 864 YQERLSGNQAPALYAIslIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAI 943
Cdd:PRK10614 845 FQETMNSQLILILAAI--ATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAI 922
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1349323678 944 LIVEFAKDLMEKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATIL 1017
Cdd:PRK10614 923 MMVDFALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLL 996
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
2-1019 |
1.56e-118 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 389.86 E-value: 1.56e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 2 AKFFIDRPIFAWVIAIIIMLAGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSST 81
Cdd:PRK10503 13 SRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 82 SdSSGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGV-SVEKSSSSFLMVLGLINTDGSMKQedIADYAGA 160
Cdd:PRK10503 93 S-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVySKVNPADPPIMTLAVTSTAMPMTQ--VEDMVET 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 161 NIKDPISRTTGVGDVQLFGSQY-AMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLGGtpPVKGQQLNASiiaqTR 239
Cdd:PRK10503 170 RVAQKISQVSGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDG--PTRAVTLSAN----DQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 240 LTSADEFSKILLKVnQDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAVRKTIAGLEPFFPS 319
Cdd:PRK10503 244 MQSAEEYRQLIIAY-QNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 320 GLKVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMV 399
Cdd:PRK10503 323 SVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALT 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMV 479
Cdd:PRK10503 403 IATGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAIL 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 480 LSVIVALILTPALCATMLKPVAKGDHGEgkkgFFGWFNRMFDKSTHHYTDSVGNILRSTGRYLLLYLLIVVAMAFLFIRL 559
Cdd:PRK10503 482 ISAVVSLTLTPMMCARMLSQESLRKQNR----FSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 560 PSSFLPDEDQGVFLTMAQLPA----GATQERTQKVLDEVTdyyltqeKD-NVNSVFTVNGFGFSGRGQNTGLAFVSLKNW 634
Cdd:PRK10503 558 PKGFFPVQDNGIIQGTLQAPQsssfANMAQRQRQVADVIL-------QDpAVQSLTSFVGVDGTNPSLNSARLQINLKPL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 635 DERpgaENKVPAITGRAMGRFSQIKDAMVFafnLPAIVELG-----TATGFDFELidQGNlGHDKLTQARNQLLGEAAQH 709
Cdd:PRK10503 631 DER---DDRVQKVIARLQTAVAKVPGVDLY---LQPTQDLTidtqvSRTQYQFTL--QAT-SLDALSTWVPKLMEKLQQL 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 710 P---DLLSQVRPNGLEDTpqfkIDIDQEKAQALGVSISDINTTLASAWGGSYVNDfidrgrvkkvyVMSQA-QYRML--- 782
Cdd:PRK10503 702 PqlsDVSSDWQDKGLVAY----VNVDRDSASRLGISMADVDNALYNAFGQRLIST-----------IYTQAnQYRVVleh 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 783 -----PG--DINNWYVRGTNGQMVPFSAFSTSHWEYGSPRLERYNGLPSMQIQGQAVQGKSTGEAMAMMEQLASKL--PT 853
Cdd:PRK10503 767 ntentPGlaALDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLnlPA 846
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 854 GIGYDWTG--MSYQERLSGNQAPALYAIslIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNNDVYFQVGL 931
Cdd:PRK10503 847 DITTQFQGstLAFQSALGSTVWLIVAAV--VAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGI 924
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 932 LTTIGLSAKNAILIVEFAKDLMEKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGM 1011
Cdd:PRK10503 925 ILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGL 1004
|
....*...
gi 1349323678 1012 VTATILAI 1019
Cdd:PRK10503 1005 IVSQVLTL 1012
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
10-1019 |
2.15e-79 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 281.26 E-value: 2.15e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 10 IFAWVIAIIimlaGGLSIMKLPVAQYPSIAPPAVTINATYPGADAKTVQDTVTQVIEQNMNGIDGLMYMSSTSdSSGTVQ 89
Cdd:TIGR00914 18 LATLVMAIL----GIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLS-RYGLSQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 90 ITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQgvsvekssssflmvLGLINTD-GSMKQEDIADYAGANIKD---- 164
Cdd:TIGR00914 93 VTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPE--------------MGPISTGlGEIFLYTVEAEEGARKKDggay 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 165 --------------PISRTT-GVGDVQLFG---SQYAMRIwlDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLggtpPVK 226
Cdd:TIGR00914 159 tltdlrtiqdwiirPQLRTVpGVAEVNSIGgyvKQFLVAP--DPEKLAAYGLSLADVVNALERNNQNVGAGYI----ERR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 227 GQQLnaSIIAQTRLTSADEFSKILLKvNQDGSRVLLRDVAKVELGGENYDIIARYNGQPAAGLGIKLATGANALDTAEAV 306
Cdd:TIGR00914 233 GEQY--LVRAPGQVQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAV 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 307 RKTIAGLEPFFPSGLKVVYPYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAF 386
Cdd:TIGR00914 310 GDKLETINKTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQ 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 387 GYSINTLTMfgMVLAIGLLVDDAIVVVENVERVMAE----EGLPPKEATR-----KSMGQIQGALVGIALVLSAVFIPMA 457
Cdd:TIGR00914 390 GISANLMSL--GALDFGLIVDGAVVIVENAHRRLAEaqhhHGRQLTLKERlhevfAASREVRRPLIFGQLIITLVFLPIF 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 458 FFGGSTGAIYRQFSITIVSAMVLSVIVALILTPALCATML-KPVAKGDHgegkkgffgWFNRMFDKSTHHYTDSVgniLR 536
Cdd:TIGR00914 468 TLTGVEGKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIrGKVAEKEN---------RLMRVLKRRYEPLLERV---LA 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 537 STGRYLLLYLLIVVAMAFLFIRLPSSFLPDEDQGVFLTMAQLPAGATqertqkvLDEVTDYYLTQEKdNVNSVFTVNG-F 615
Cdd:TIGR00914 536 WPAVVLGAAAVSIVLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTS-------LAQSVAMQQTLEK-LIKSFPEVARvF 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 616 GFSGRGQ--------NTGLAFVSLKNWDE-RPGAENKVPAI------TGRAMGRFSQIKDAMVFAFNlpaivELGTATGF 680
Cdd:TIGR00914 608 AKTGTAEiatdpmppNASDTYIILKPESQwPEGKKTKEDLIeeiqeaTVRIPGNNYEFTQPIQMRFN-----ELISGVRS 682
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 681 DFELIDQGNLGHDKLTQArnQLLGEAAQHPDLLSQVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLASAWGGSYVN 760
Cdd:TIGR00914 683 DVAVKVFGDDLDDLDATA--EKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSG 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 761 DFIDRGRVKKVYVMSQAQYRMLPGDINNWYV-----RGTNGQMVPFSAFSTSHWEYGSPRLERYNGLPSMQIQGQaVQGK 835
Cdd:TIGR00914 761 ETFEGDRRFDIVIRLPESLRESPQALRQLPIplplsEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSAN-VRGR 839
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 836 STGE-----AMAMMEQLasKLPTGIGYDWTGmSYQERLSGNQAPALYA-ISLIVVFLCLAALYESWSIPFSVMLVVPLGV 909
Cdd:TIGR00914 840 DLGSfvddaKKAIAEQV--KLPPGYWITWGG-QFEQLQSATKRLQIVVpVTLLLIFVLLYAAFGNVKDALLVFTGIPFAL 916
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 910 IGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEkEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPL 989
Cdd:TIGR00914 917 TGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLE-EGPSLDEAVYEGALTRVRPVLMTALVASLGFVPM 995
|
1050 1060 1070
....*....|....*....|....*....|
gi 1349323678 990 VISSGAGSGAQNAVGTGVMGGMVTATILAI 1019
Cdd:TIGR00914 996 AIATGTGAEVQRPLATVVIGGIITATLLTL 1025
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
291-1018 |
2.48e-19 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 93.77 E-value: 2.48e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 291 IKLATGANALDTAEAVRKTIAGLEPFFPSGLKVVY---PYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLI 367
Cdd:COG1033 168 LDPDPLSSDLDRKEVVAEIRAIIAKYEDPGVEVYLtgfPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 368 PTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAeEGLPPKEATRKSMGQiqgalVGIAL 447
Cdd:COG1033 248 PLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERR-KGLDKREALREALRK-----LGPPV 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 448 VLSAV-----FIPMAFfggSTGAIYRQFSITIVSAMVLSVIVALILTPALCATMLKPVAKGDHGEGKKGFFGWFNRMFDK 522
Cdd:COG1033 322 LLTSLttaigFLSLLF---SDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLAKLARF 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 523 STHHYTdsvgnilrstgrylllylLIVVAMAFLFIrlpssflpdedqGVFLTMAQLPAGATQERTqkvLDEVTDYYltQE 602
Cdd:COG1033 399 VLRRPK------------------VILVVALVLAV------------VSLYGISRLKVEYDFEDY---LPEDSPIR--QD 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 603 KDNVNSVFTvngfgfsgrGQNTglAFVSLKnWDERPGAENkvpAITGRAMGRFSQikdamvfafNLPAIVELGTATGFdf 682
Cdd:COG1033 444 LDFIEENFG---------GSDP--LEVVVD-TGEPDGLKD---PEVLKEIDRLQD---------YLESLPEVGKVLSL-- 497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 683 elidqgnlghdkltqarnqllgeaaqhPDLLSQVRPNGLEDTPQ-FKIDIDQEKAQALgvsisdinTTLASAWGGSYVND 761
Cdd:COG1033 498 ---------------------------ADLVKELNQALNEGDPKyYALPESRELLAQL--------LLLLSSPPGDDLSR 542
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 762 FIDrgrvkkvyvmsqaqyrmlpgdinnwyvrgTNGQMVPFSAFSTSHweygsprlerynglpsmqiqgqavqgkSTGEAM 841
Cdd:COG1033 543 FVD-----------------------------EDYSAARVTVRLKDL---------------------------DSEEIK 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 842 AMMEQLASKL-----PTGIGYDWTGMSY-----QERLSGNQAPALyAISLIVVFLCLAALYESWSIPFSVML--VVPLGV 909
Cdd:COG1033 567 ALVEEVRAFLaenfpPDGVEVTLTGSAVlfaaiNESVIESQIRSL-LLALLLIFLLLLLAFRSLRLGLISLIpnLLPILL 645
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 910 IGALLAASlrglnnDVYFQVGLLT----TIGLSAKNAILIVEFAKDLMeKEGKGLIEATLEAVRMRLRPILMTSLAFILG 985
Cdd:COG1033 646 TFGLMGLL------GIPLNIATAVvasiALGIGVDYTIHFLSRYREER-RKGGDLEEAIRRALRTTGKAILFTSLTLAAG 718
|
730 740 750
....*....|....*....|....*....|...
gi 1349323678 986 VMPLVISSGagsgaqnaVGTGVMGGMVTATILA 1018
Cdd:COG1033 719 FGVLLFSSF--------PPLADFGLLLALGLLV 743
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
341-496 |
7.04e-18 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 89.15 E-value: 7.04e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 341 VKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420
Cdd:COG1033 608 IRSLLLALLLIFLLLLLAFRSLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREER 687
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1349323678 421 aEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFfggSTGAIYRQFSITIVSAMVLSVIVALILTPALCATM 496
Cdd:COG1033 688 -RKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLF---SSFPPLADFGLLLALGLLVALLAALLLLPALLLLL 759
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
159-492 |
2.76e-10 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 64.66 E-value: 2.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 159 GANIKDPISRTTGVGDVQLF--GSQYAMRIWLDPNKLNNFQLTPVDVISAIKAQNAQVAAGQLggtppVKGQQ---LNAS 233
Cdd:COG3696 691 AEQIEAVLKTVPGAADVQVErvTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQV-----YEGERrfdIVVR 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 234 IIAQTRlTSADEFSKILLKVnQDGSRVLLRDVAKVELG-GENYdiIARYNGQPAAGLGIKLAtGANALDTAEAVRKTIAG 312
Cdd:COG3696 766 LPEELR-DDPEAIRNLPIPT-PSGAQVPLSQVADIEVVeGPNQ--ISRENGRRRIVVQANVR-GRDLGSFVAEAQAKVAE 840
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 313 -LEpfFPSG------------------LKVVYPYdttpfvkisifevvktlveAIVLVFLVMYLFLQNFRATLIPTIAVP 373
Cdd:COG3696 841 qVK--LPPGyyiewggqfenlqratarLAIVVPL-------------------ALLLIFLLLYLAFGSVRDALLILLNVP 899
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 374 VVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMaEEGLPPKEATrksmgqIQGALVGI------AL 447
Cdd:COG3696 900 FALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLR-AEGLDLREAI------IEGALERLrpvlmtAL 972
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1349323678 448 VLSAVFIPMAfFGGSTGA-IYRQFSITIVSAMVLSVIVALILTPAL 492
Cdd:COG3696 973 VAALGLLPMA-LSTGPGSeVQRPLATVVIGGLITSTLLTLLVLPAL 1017
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
299-494 |
6.68e-09 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 58.84 E-value: 6.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 299 ALDTAEAVRKTIAGLEPffPSGLKVvypYDTTP------FVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRATLIPTIAV 372
Cdd:pfam03176 102 ADESVAAVRDAVEQAPP--PEGLKA---YLTGPaatvadLRDAGDRDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTV 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 373 PVVLLGTFAILAAFGY----SINTLT-MFGMVLAIGLLVDDAIVVvenVERVMAE--EGLPPKEATRKSMGQIQGALVGI 445
Cdd:pfam03176 177 GLSLGAAQGLVAILAHilgiGLSTFAlNLLVVLLIAVGTDYALFL---VSRYREElrAGEDREEAVIRAVRGTGKVVTAA 253
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1349323678 446 ALVLSAVFIPMAFfggSTGAIYRQFSITIVSAMVLSVIVALILTPALCA 494
Cdd:pfam03176 254 GLTVAIAMLALSF---ARLPVFAQVGPTIAIGVLVDVLAALTLLPALLA 299
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
289-516 |
1.01e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 59.39 E-value: 1.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 289 LGIKLATGANALDTAEAVRKTIAGLEPffpSGLKVVY---PYDTTPFVKISIFEVVKTLVEAIVLVFLVMYLFLQNFRAT 365
Cdd:COG2409 120 VTLDGDAGDEAAEAVDALRDAVAAAPA---PGLTVYVtgpAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 366 LIPTIAVPVVLLGTFAILAAFGYSI---NTLTMFGMVLAIGLLVDDAIVVV----ENVERvmaeeGLPPKEATRKSMGQI 438
Cdd:COG2409 197 LLPLLTAGLAVGVALGLLALLAAFTdvsSFAPNLLTMLGLGVGIDYALFLVsryrEELRA-----GEDREEAVARAVATA 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 439 Q------GALVGIALvLSAVFIPMAFFggstgaiyRQFSITIVSAMVLSVIVALILTPALCATM------LKPVAKGDHG 506
Cdd:COG2409 272 GravlfsGLTVAIAL-LGLLLAGLPFL--------RSMGPAAAIGVAVAVLAALTLLPALLALLgrrvfwPRRPRRRRAA 342
|
250
....*....|
gi 1349323678 507 EGKKGFFGWF 516
Cdd:COG2409 343 APESGFWRRL 352
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
341-492 |
9.38e-07 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 52.29 E-value: 9.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 341 VKTLVEAIVLVFLVMYLFLQNFraTLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420
Cdd:TIGR01129 251 IKAGLIGLVLVLVFMILYYRLF--GLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEEL 328
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1349323678 421 AeEGLPPKEAT----RKSMGQIQGAlvGIALVLSAVFipMAFFGgsTGAIyRQFSITIVSAMVLSVIVALILTPAL 492
Cdd:TIGR01129 329 R-LGKSVRQAIeagfERAFSTIFDA--NITTLIAALI--LYVFG--TGPV-KGFAVTLAIGIIASLFTALVFTRLL 396
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
347-491 |
3.86e-06 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 51.01 E-value: 3.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 347 AIVLVFLVMYLFLQNFRATLIpTIAVPVV-LLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIvvvenverVMAEEGL 425
Cdd:COG4258 648 ALLLILLLLLLRLRSLRRALR-VLLPPLLaVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL--------FFTEGLL 718
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1349323678 426 PPKEATRksmgqiqgALVGIAL-VLSAV--FIPMAFfgGSTGAIyRQFSITIVSAMVLSVIVALILTPA 491
Cdd:COG4258 719 DKGELAR--------TLLSILLaALTTLlgFGLLAF--SSTPAL-RSFGLTVLLGILLALLLAPLLAPR 776
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
347-503 |
4.10e-06 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 50.91 E-value: 4.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 347 AIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVeRVMAEEGLP 426
Cdd:TIGR00914 887 TLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFI-RKLLEEGPS 965
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 427 PKEATrksmgqIQGALVGI------ALVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMVLSVIVALILTPALCATMLKPV 500
Cdd:TIGR00914 966 LDEAV------YEGALTRVrpvlmtALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHRRR 1039
|
...
gi 1349323678 501 AKG 503
Cdd:TIGR00914 1040 HKG 1042
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
347-492 |
2.32e-05 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 48.19 E-value: 2.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 347 AIVLVFLVMYLFLQNFRatLIPTIAVPVVLLGTFAILAAFGYsinTLTM---FGMVLAIGLLVDDaivvveNV---ERVM 420
Cdd:COG0342 280 GLLLVALFMLLYYRLPG--LVANIALALNVVLLLGVLSLLGA---TLTLpgiAGIILTIGMAVDA------NVlifERIR 348
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1349323678 421 AE--EGLPPKEAT----RKSMGQIQGAlvGIALVLSAVfiPMAFFGgsTGAIyRQFSITIVSAMVLSVIVALILTPAL 492
Cdd:COG0342 349 EElrAGRSLRAAIeagfKRAFSTILDA--NVTTLIAAV--VLFVLG--TGPV-KGFAVTLILGILISMFTAVPVTRPL 419
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
317-492 |
3.32e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 47.91 E-value: 3.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 317 FPSGLKVVYPYDttPFVKISIFE-----VVKTLVEAIVLVFLVMYLFLQNFRATLIPtiaVPVVLLGTFAILAAFGY--- 388
Cdd:TIGR00921 169 PPSGKFLDVTGS--PAINYDIERefgkdMGTTMAISGILVVLVLLLDFKRWWRPLLP---LVIILFGVAWVLGIMGWlgi 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 389 --SINTLTMFGMVLAIGLlvdDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFfggSTGAI 466
Cdd:TIGR00921 244 plYATTLLAVPMLIGVGI---DYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALAL---SEFPM 317
|
170 180
....*....|....*....|....*.
gi 1349323678 467 YRQFSITIVSAMVLSVIVALILTPAL 492
Cdd:TIGR00921 318 VSEFGLGLVAGLITAYLLTLLVLPAL 343
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
341-492 |
5.47e-05 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 47.35 E-value: 5.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 341 VKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERvm 420
Cdd:pfam02460 642 IQNIVITLICMFIVCFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYHFVR-- 719
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1349323678 421 aEEGLPPKEATRKSMGQI-----QGALVGIALVLSAVFIPmaffggsTGAIyRQFSITIVSAMVLSVIVALILTPAL 492
Cdd:pfam02460 720 -SRGDTPAERVVDALEALgwpvfQGGLSTILGVLVLLFVP-------SYMV-VVFFKTVFLVVAIGLLHGLFILPII 787
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
347-489 |
1.07e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 46.38 E-value: 1.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 347 AIVLVFLVMYLFLQnfRATLIPTIAVPVVLLGTFAILAAFGysiNTLTM---FGMVLAIGLLVDDAIVVVENVErvmaEE 423
Cdd:PRK13024 275 GFALIFLFMLVYYG--LPGLIANIALLLYIFLTLGALSSLG---AVLTLpgiAGLVLGIGMAVDANVLIFERIK----EE 345
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1349323678 424 ---GLPPKEATRKSMgqiQGALVGIA-----LVLSAV--FipmaFFGgsTGAIyRQFSITIVSAMVLSVIVALILT 489
Cdd:PRK13024 346 lrkGKSLKKAFKKGF---KNAFSTILdsnitTLIAAAilF----FFG--TGPV-KGFATTLIIGILASLFTAVFLT 411
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
341-486 |
2.43e-04 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 43.40 E-value: 2.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 341 VKTLVEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLgTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENV-ERV 419
Cdd:TIGR00916 50 IIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVIL-ILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDRIrEEL 128
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1349323678 420 MAEEGLPPKEATRKSMGQIQGALVGIALVLSAVFIPMAFFGGstGAIyRQFSITIVSAMVLSVIVAL 486
Cdd:TIGR00916 129 RKYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGG--GAI-KGFALTLGIGVIAGTYSSI 192
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
849-1019 |
1.09e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 42.90 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 849 SKLPTGIGYDWTG---MSYQ-ERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAASLRGLNND 924
Cdd:TIGR00921 167 TNPPSGKFLDVTGspaINYDiEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLY 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 925 VYFQVGLLTTIGLsaknAILIVEFAKDLMEKE---GKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISsgaGSGAQN 1001
Cdd:TIGR00921 247 ATTLLAVPMLIGV----GIDYGIQTLNRYEEErdiGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALS---EFPMVS 319
|
170
....*....|....*...
gi 1349323678 1002 AVGTGVMGGMVTATILAI 1019
Cdd:TIGR00921 320 EFGLGLVAGLITAYLLTL 337
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
344-502 |
6.37e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 40.75 E-value: 6.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 344 LVEAIVLVFLVMYLFLQNFR---ATLIPTIavpVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVeRVM 420
Cdd:TIGR03480 275 GLLSFVLVLVLLWLALRSPRlvfAVLVTLI---VGLILTAAFATLAVGHLNLISVAFAVLFIGLGVDFAIQFSLRY-REE 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 421 AEEGLPPKEATRKSMGQIQGALVGIALVLSA---VFIPMAFFGGStgaiyrQFSITIVSAMVLSVIVALILTPALCaTML 497
Cdd:TIGR03480 351 RFRGGNHREALSVAARRMGAALLLAALATAAgffAFLPTDYKGVS------ELGIIAGTGMFIALFVTLTVLPALL-RLL 423
|
....*
gi 1349323678 498 KPVAK 502
Cdd:TIGR03480 424 RPPRR 428
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
347-492 |
9.62e-03 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 39.82 E-value: 9.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 347 AIVLVFLVMYlflqnFR-ATLIPTIAVPVVLLGTFAILAAFGYsinTLT---MFGMVLAIGLLVdDAIVVVenVERVMAE 422
Cdd:PRK05812 308 ALVLLFMILY-----YRlFGLIANIALVANLVLILAVLSLLGA---TLTlpgIAGIVLTIGMAV-DANVLI--FERIREE 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349323678 423 --EGLPPKEAT----RKSMGQIQGA-----LVGIALvlsavFipmaFFGgsTGAIyRQFSITIVSAMVLSVIVALILTPA 491
Cdd:PRK05812 377 lrEGRSLRSAIeagfKRAFSTILDSnittlIAAIIL-----Y----ALG--TGPV-KGFAVTLGIGILTSMFTAITVTRA 444
|
.
gi 1349323678 492 L 492
Cdd:PRK05812 445 L 445
|
|
| |
