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Conserved domains on  [gi|1368529037|gb|PSJ85095|]
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DUF2089 domain-containing protein [Clostridioides difficile]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2089 super family cl22936
Protein of unknown function (DUF2089); This domain, found in various hypothetical prokaryotic ...
 9-66 1.84e-12

Protein of unknown function (DUF2089); This domain, found in various hypothetical prokaryotic proteins, has no known function. This domain is a zinc-ribbon.


The actual alignment was detected with superfamily member COG3877:

Pssm-ID: 473997  Cd Length: 120  Bit Score: 58.31  E-value: 1.84e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1368529037   9 WILALEQEDATFLKNFALKSGSLKEIAKMYGVSYPTVRLRLDKLIQKIEMCDQQEEEP 66
Cdd:COG3877    38 KFARLTPEQLEFVELFLKCRGNLKEVEKELGISYPTVRNRLDEIIAALGYEPEEEEEE 95
 
Name Accession Description Interval E-value
COG3877 COG3877
Predicted DNA-binding transcriptional regulator with XRE-family HTH domain, DUF2089 family ...
 9-66 1.84e-12

Predicted DNA-binding transcriptional regulator with XRE-family HTH domain, DUF2089 family [Transcription];


Pssm-ID: 443085  Cd Length: 120  Bit Score: 58.31  E-value: 1.84e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1368529037   9 WILALEQEDATFLKNFALKSGSLKEIAKMYGVSYPTVRLRLDKLIQKIEMCDQQEEEP 66
Cdd:COG3877    38 KFARLTPEQLEFVELFLKCRGNLKEVEKELGISYPTVRNRLDEIIAALGYEPEEEEEE 95
DUF2089 pfam09862
Protein of unknown function (DUF2089); This domain, found in various hypothetical prokaryotic ...
 13-72 7.13e-11

Protein of unknown function (DUF2089); This domain, found in various hypothetical prokaryotic proteins, has no known function. This domain is a zinc-ribbon.


Pssm-ID: 462920  Cd Length: 113  Bit Score: 54.10  E-value: 7.13e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1368529037  13 LEQEDATFLKNFALKSGSLKEIAKMYGVSYPTVRLRLDKLIQKIEMCDQQEEEPFQTFIK 72
Cdd:pfam09862  34 LSPEQLEFVELFLKCRGNLKEVEKELGISYPTVRNRLDEILRALGYEPEEEDEEEVPERK 93
HTH_ASNC smart00344
helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase ...
 3-55 6.72e-03

helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli)


Pssm-ID: 214628 [Multi-domain]  Cd Length: 108  Bit Score: 33.26  E-value: 6.72e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1368529037    3 LDKIPQWILALEQEDATFlknfalksgSLKEIAKMYGVSYPTVRLRLDKLIQK 55
Cdd:smart00344   1 LDEIDRKILEELQKDARI---------SLAELAKKVGLSPSTVHNRVKRLEEE 44
 
Name Accession Description Interval E-value
COG3877 COG3877
Predicted DNA-binding transcriptional regulator with XRE-family HTH domain, DUF2089 family ...
 9-66 1.84e-12

Predicted DNA-binding transcriptional regulator with XRE-family HTH domain, DUF2089 family [Transcription];


Pssm-ID: 443085  Cd Length: 120  Bit Score: 58.31  E-value: 1.84e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1368529037   9 WILALEQEDATFLKNFALKSGSLKEIAKMYGVSYPTVRLRLDKLIQKIEMCDQQEEEP 66
Cdd:COG3877    38 KFARLTPEQLEFVELFLKCRGNLKEVEKELGISYPTVRNRLDEIIAALGYEPEEEEEE 95
DUF2089 pfam09862
Protein of unknown function (DUF2089); This domain, found in various hypothetical prokaryotic ...
 13-72 7.13e-11

Protein of unknown function (DUF2089); This domain, found in various hypothetical prokaryotic proteins, has no known function. This domain is a zinc-ribbon.


Pssm-ID: 462920  Cd Length: 113  Bit Score: 54.10  E-value: 7.13e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1368529037  13 LEQEDATFLKNFALKSGSLKEIAKMYGVSYPTVRLRLDKLIQKIEMCDQQEEEPFQTFIK 72
Cdd:pfam09862  34 LSPEQLEFVELFLKCRGNLKEVEKELGISYPTVRNRLDEILRALGYEPEEEDEEEVPERK 93
Lrp COG1522
DNA-binding transcriptional regulator, Lrp family [Transcription];
1-55 7.96e-04

DNA-binding transcriptional regulator, Lrp family [Transcription];


Pssm-ID: 441131 [Multi-domain]  Cd Length: 138  Bit Score: 35.91  E-value: 7.96e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1368529037   1 MELDKIPQWILALEQEDAtflknfalkSGSLKEIAKMYGVSYPTVRLRLDKLIQK 55
Cdd:COG1522     1 MELDEIDRRILRLLQEDG---------RLSFAELAERVGLSESTVLRRVRRLEEA 46
HTH_AsnC-type pfam13404
AsnC-type helix-turn-helix domain;
4-52 4.23e-03

AsnC-type helix-turn-helix domain;


Pssm-ID: 433180 [Multi-domain]  Cd Length: 41  Bit Score: 32.34  E-value: 4.23e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 1368529037  4 DKIPQWILALEQEDATFlknfalksgSLKEIAKMYGVSYPTVRLRLDKL 52
Cdd:pfam13404  1 DEIDRKILRLLQEDARI---------SFAELAERVGLSESTVLRRIRRL 40
HTH_ASNC smart00344
helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase ...
 3-55 6.72e-03

helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli)


Pssm-ID: 214628 [Multi-domain]  Cd Length: 108  Bit Score: 33.26  E-value: 6.72e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1368529037    3 LDKIPQWILALEQEDATFlknfalksgSLKEIAKMYGVSYPTVRLRLDKLIQK 55
Cdd:smart00344   1 LDEIDRKILEELQKDARI---------SLAELAKKVGLSPSTVHNRVKRLEEE 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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