|
Name |
Accession |
Description |
Interval |
E-value |
| IlvA |
COG1171 |
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the ... |
1-317 |
6.94e-150 |
|
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440784 [Multi-domain] Cd Length: 327 Bit Score: 423.68 E-value: 6.94e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 1 MTGTVPTRATIEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSS 80
Cdd:COG1171 1 MTALMPTLADIEAAAARIAGVVRRTPLLRSPTLSERLGAEVYLKLENLQPTGSFKLRGAYNALASLSEEERARGVVAASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 81 GNHAQAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQA 160
Cdd:COG1171 81 GNHAQGVAYAARLLGIPATIVMPETAPAVKVAATRAYGAEVVLHGDTYDDAEAAAAELAEEEGATFVHPFDDPDVIAGQG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 161 TAAKELIEDLTvTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGLLT-Y 239
Cdd:COG1171 161 TIALEILEQLP-DLDAVFVPVGGGGLIAGVAAALKALSPDIRVIGVEPEGAAAMYRSLAAGEPVTLPGVDTIADGLAVgR 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1369174260 240 LGDKTFPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKKVGIIISGGNVDLGRLPF 317
Cdd:COG1171 240 PGELTFEILRDLVDDIVTVSEDEIAAAMRLLLERTKIVVEPAGAAALAALLAGKERLKGKRVVVVLSGGNIDPDRLAE 317
|
|
| Thr-dehyd |
cd01562 |
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. ... |
11-311 |
3.97e-144 |
|
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.
Pssm-ID: 107205 [Multi-domain] Cd Length: 304 Bit Score: 408.03 E-value: 3.97e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 11 IEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQAIAFS 90
Cdd:cd01562 4 ILAAAARIKPVVRRTPLLTSPTLSELLGAEVYLKCENLQKTGSFKIRGAYNKLLSLSEEERAKGVVAASAGNHAQGVAYA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 91 AQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKELIEDL 170
Cdd:cd01562 84 AKLLGIPATIVMPETAPAAKVDATRAYGAEVVLYGEDFDEAEAKARELAEEEGLTFIHPFDDPDVIAGQGTIGLEILEQV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 171 tVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGLLT-YLGDKTFPIIK 249
Cdd:cd01562 164 -PDLDAVFVPVGGGGLIAGIATAVKALSPNTKVIGVEPEGAPAMAQSLAAGKPVTLPEVDTIADGLAVkRPGELTFEIIR 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1369174260 250 AEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKKVGIIISGGNVD 311
Cdd:cd01562 243 KLVDDVVTVSEDEIAAAMLLLFEREKLVAEPAGALALAALLSGKLDLKGKKVVVVLSGGNID 304
|
|
| PLN02970 |
PLN02970 |
serine racemase |
11-315 |
1.08e-138 |
|
serine racemase
Pssm-ID: 215524 [Multi-domain] Cd Length: 328 Bit Score: 395.20 E-value: 1.08e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 11 IEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQAIAFS 90
Cdd:PLN02970 14 IREARKRIAPFIHRTPVLTSSSLDALAGRSLFFKCECFQKGGAFKFRGACNAIFSLSDDQAEKGVVTHSSGNHAAALALA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 91 AQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKELIEDL 170
Cdd:PLN02970 94 AKLRGIPAYIVVPKNAPACKVDAVIRYGGIITWCEPTVESREAVAARVQQETGAVLIHPYNDGRVISGQGTIALEFLEQV 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 171 TvTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGLLTYLGDKTFPIIKA 250
Cdd:PLN02970 174 P-ELDVIIVPISGGGLISGIALAAKAIKPSIKIIAAEPKGADDAAQSKAAGEIITLPVTNTIADGLRASLGDLTWPVVRD 252
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 251 EVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVL-----KNKAVFEGKKVGIIISGGNVDLGRL 315
Cdd:PLN02970 253 LVDDVITVDDKEIIEAMKLCYERLKVVVEPSGAIGLAAALsdsfrSNPAWKGCKNVGIVLSGGNVDLGVL 322
|
|
| PRK07048 |
PRK07048 |
threo-3-hydroxy-L-aspartate ammonia-lyase; |
1-315 |
1.56e-134 |
|
threo-3-hydroxy-L-aspartate ammonia-lyase;
Pssm-ID: 235918 [Multi-domain] Cd Length: 321 Bit Score: 384.37 E-value: 1.56e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 1 MTGTVPTRATIEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSS 80
Cdd:PRK07048 1 SDLLLPTYDDVAAAAARLAGVAHRTPVLTSRTADARTGAQVFFKCENFQRMGAFKFRGAYNALSQFSPEQRRAGVVTFSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 81 GNHAQAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQA 160
Cdd:PRK07048 81 GNHAQAIALSARLLGIPATIVMPQDAPAAKVAATRGYGGEVVTYDRYTEDREEIGRRLAEERGLTLIPPYDHPHVIAGQG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 161 TAAKELIEDlTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGLLT-Y 239
Cdd:PRK07048 161 TAAKELFEE-VGPLDALFVCLGGGGLLSGCALAARALSPGCKVYGVEPEAGNDGQQSFRSGEIVHIDTPRTIADGAQTqH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1369174260 240 LGDKTFPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKKVGIIISGGNVDLGRL 315
Cdd:PRK07048 240 LGNYTFPIIRRLVDDIVTVSDAELVDAMRFFAERMKIVVEPTGCLGAAAALRGKVPLKGKRVGVIISGGNVDLARF 315
|
|
| ilvA_1Cterm |
TIGR01127 |
threonine ammonia-lyase, medium form; A form of threonine dehydratase with two copies of the ... |
25-312 |
6.66e-94 |
|
threonine ammonia-lyase, medium form; A form of threonine dehydratase with two copies of the C-terminal domain pfam00585 is described by TIGR01124. This model describes a phylogenetically distinct form with a single copy of pfam00585. This form branches with the catabolic threonine dehydratase of E. coli; many members are designated as catabolic for this reason. However, the catabolic form lacks any pfam00585 domain. Many members of this model are found in species with other Ile biosynthetic enzymes. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130197 [Multi-domain] Cd Length: 380 Bit Score: 283.56 E-value: 6.66e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 25 TPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMPD 104
Cdd:TIGR01127 1 TPLIYSTTLSDITGSEVYLKLENLQKTGSFKIRGALNKIANLSEDQRQRGVVAASAGNHAQGVAYAAKKFGIKAVIVMPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 105 NSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKELIEDLTvTLDAIIAPVGGG 184
Cdd:TIGR01127 81 SAPPSKVKATKSYGAEVILHGDDYDEAYAFATSLAEEEGRVFVHPFDDEFVMAGQGTIGLEIMEDIP-DVDTVIVPVGGG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 185 GLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGLLT-YLGDKTFPIIKAEVTDIFTVSDEEI 263
Cdd:TIGR01127 160 GLISGVASAAKQINPNVKVIGVEAEGAPSMYESLREGKIKAVESVRTIADGIAVkKPGDLTFNIIKEYVDDVVTVDEEEI 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1369174260 264 IQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKKVGIIISGGNVDL 312
Cdd:TIGR01127 240 ANAIYLLLERHKILAEGAGAAGVAALLEQKVDVKGKKIAVVLSGGNIDL 288
|
|
| PRK06608 |
PRK06608 |
serine/threonine dehydratase; |
9-311 |
1.67e-88 |
|
serine/threonine dehydratase;
Pssm-ID: 235842 [Multi-domain] Cd Length: 338 Bit Score: 268.18 E-value: 1.67e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 9 ATIEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAE-QLANGVITHSSGNHAQAI 87
Cdd:PRK06608 8 QNIAAAHNRIKQYLHLTPIVHSESLNEMLGHEIFFKVESLQKTGAFKVRGVLNHLLELKEQgKLPDKIVAYSTGNHGQAV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 88 AFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEdrqgtVDEIVART---GATFIHPFNNYEVITGQATAAK 164
Cdd:PRK06608 88 AYASKLFGIKTRIYLPLNTSKVKQQAALYYGGEVILTNTRQE-----AEEKAKEDeeqGFYYIHPSDSDSTIAGAGTLCY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 165 ELIEDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYV-NTIADGLLTY-LGD 242
Cdd:PRK06608 163 EALQQLGFSPDAIFASCGGGGLISGTYLAKELISPTSLLIGSEPLNANDAYLSLKNNKIYRLNYSpNTIADGLKTLsVSA 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1369174260 243 KTFPIIKaEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAV---LKNKAvfEGKKVGIIISGGNVD 311
Cdd:PRK06608 243 RTFEYLK-KLDDFYLVEEYEIYYWTAWLTHLLKVICEPSSAINMVAVvnwLKTQS--KPQKLLVILSGGNID 311
|
|
| PRK08638 |
PRK08638 |
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB; |
10-315 |
6.79e-84 |
|
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB;
Pssm-ID: 236317 [Multi-domain] Cd Length: 333 Bit Score: 256.20 E-value: 6.79e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 10 TIEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQAIAF 89
Cdd:PRK08638 13 DIIEAKQRLAGRIRKTPLPRSNYLSERCKGEIFLKLENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVAL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 90 SAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKELIED 169
Cdd:PRK08638 93 SCALLGIDGKVVMPKGAPKSKVAATCGYGAEVVLHGDNFNDTIAKVEEIVEEEGRTFIPPYDDPKVIAGQGTIGLEILED 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 170 LtVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGL-LTYLGDKTFPII 248
Cdd:PRK08638 173 L-WDVDTVIVPIGGGGLIAGIAVALKSINPTIHIIGVQSENVHGMAASFYAGEITTHRTTGTLADGCdVSRPGNLTYEIV 251
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1369174260 249 KAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNK--AVFEGKKVGIIISGGNVDLGRL 315
Cdd:PRK08638 252 RELVDDIVLVSEDEIRNAMKDLIQRNKVVTEGAGALATAALLSGKldQYIQNKKVVAIISGGNVDLSRV 320
|
|
| PALP |
pfam00291 |
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate ... |
25-307 |
1.63e-80 |
|
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Pssm-ID: 459749 [Multi-domain] Cd Length: 295 Bit Score: 246.07 E-value: 1.63e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 25 TPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMPD 104
Cdd:pfam00291 8 TPLVRLPRLSKELGVDVYLKLESLNPTGSFKDRGALNLLLRLKEGEGGKTVVEASSGNHGRALAAAAARLGLKVTIVVPE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 105 NSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVAR-TGATFIHPFNNYEVITGQATAAKELIEDLTVTLDAIIAPVGG 183
Cdd:pfam00291 88 DAPPGKLLLMRALGAEVVLVGGDYDEAVAAARELAAEgPGAYYINQYDNPLNIEGYGTIGLEILEQLGGDPDAVVVPVGG 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 184 GGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGL--LTYLGDKTFPIIKAEVTDIFTVSDE 261
Cdd:pfam00291 168 GGLIAGIARGLKELGPDVRVIGVEPEGAPALARSLAAGRPVPVPVADTIADGLgvGDEPGALALDLLDEYVGEVVTVSDE 247
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1369174260 262 EIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKA--VFEGKKVGIIISG 307
Cdd:pfam00291 248 EALEAMRLLARREGIVVEPSSAAALAALKLALAgeLKGGDRVVVVLTG 295
|
|
| PRK07334 |
PRK07334 |
threonine dehydratase; Provisional |
7-311 |
1.82e-75 |
|
threonine dehydratase; Provisional
Pssm-ID: 235994 [Multi-domain] Cd Length: 403 Bit Score: 236.71 E-value: 1.82e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 7 TRATIEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQA 86
Cdd:PRK07334 6 TLADIRAAAARLAGQVLRTPCVHSRTLSQITGAEVWLKFENLQFTASFKERGALNKLLLLTEEERARGVIAMSAGNHAQG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 87 IAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKEL 166
Cdd:PRK07334 86 VAYHAQRLGIPATIVMPRFTPTVKVERTRGFGAEVVLHGETLDEARAHARELAEEEGLTFVHPYDDPAVIAGQGTVALEM 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 167 IEDLTvTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYvnTIADGL-LTYLGDKTF 245
Cdd:PRK07334 166 LEDAP-DLDTLVVPIGGGGLISGMATAAKALKPDIEIIGVQTELYPSMYAAIKGVALPCGGS--TIAEGIaVKQPGQLTL 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1369174260 246 PIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKKVGIIISGGNVD 311
Cdd:PRK07334 243 EIVRRLVDDILLVSEADIEQAVSLLLEIEKTVVEGAGAAGLAALLAYPERFRGRKVGLVLSGGNID 308
|
|
| PRK08639 |
PRK08639 |
threonine dehydratase; Validated |
4-316 |
1.71e-74 |
|
threonine dehydratase; Validated
Pssm-ID: 236318 [Multi-domain] Cd Length: 420 Bit Score: 234.70 E-value: 1.71e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 4 TVPTRATIEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNH 83
Cdd:PRK08639 5 MTVSAKDIDKAAKRLKDVVPETPLQRNDYLSEKYGANVYLKREDLQPVRSYKLRGAYNAISQLSDEELAAGVVCASAGNH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 84 AQAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGA---TITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQA 160
Cdd:PRK08639 85 AQGVAYACRHLGIPGVIFMPVTTPQQKIDQVRFFGGefvEIVLVGDTFDDSAAAAQEYAEETGATFIPPFDDPDVIAGQG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 161 TAAKELIEDLT--VTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGL-L 237
Cdd:PRK08639 165 TVAVEILEQLEkeGSPDYVFVPVGGGGLISGVTTYLKERSPKTKIIGVEPAGAASMKAALEAGKPVTLEKIDKFVDGAaV 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1369174260 238 TYLGDKTFPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKKVGIIISGGNVDLGRLP 316
Cdd:PRK08639 245 ARVGDLTFEILKDVVDDVVLVPEGAVCTTILELYNKEGIVAEPAGALSIAALELYKDEIKGKTVVCVISGGNNDIERMP 323
|
|
| PRK06815 |
PRK06815 |
threonine/serine dehydratase; |
10-315 |
1.78e-74 |
|
threonine/serine dehydratase;
Pssm-ID: 180709 [Multi-domain] Cd Length: 317 Bit Score: 231.51 E-value: 1.78e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 10 TIEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQAIAF 89
Cdd:PRK06815 6 AILEAHQRLRPQVRVTPLEHSPLLSQHTGCEVYLKCEHLQHTGSFKFRGASNKLRLLNEAQRQQGVITASSGNHGQGVAL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 90 SAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKELIED 169
Cdd:PRK06815 86 AAKLAGIPVTVYAPEQASAIKLDAIRALGAEVRLYGGDALNAELAARRAAEQQGKVYISPYNDPQVIAGQGTIGMELVEQ 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 170 LTvTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGLLTYL--GDKTFPI 247
Cdd:PRK06815 166 QP-DLDAVFVAVGGGGLISGIATYLKTLSPKTEIIGCWPANSPSLYTSLEAGEIVEVAEQPTLSDGTAGGVepGAITFPL 244
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1369174260 248 IKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKKVGIIISGGNVDLGRL 315
Cdd:PRK06815 245 CQQLIDQKVLVSEEEIKEAMRLIAETDRWLIEGAAGVALAAALKLAPRYQGKKVAVVLCGKNIVLEKY 312
|
|
| eutB |
PRK07476 |
threonine dehydratase; Provisional |
7-313 |
3.38e-69 |
|
threonine dehydratase; Provisional
Pssm-ID: 236025 [Multi-domain] Cd Length: 322 Bit Score: 218.30 E-value: 3.38e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 7 TRATIEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQA 86
Cdd:PRK07476 2 SLADIYRARRRIAGRVRRTPLVASASLSARAGVPVWLKLETLQPTGSFKLRGATNALLSLSAQERARGVVTASTGNHGRA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 87 IAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKEL 166
Cdd:PRK07476 82 LAYAARALGIRATICMSRLVPANKVDAIRALGAEVRIVGRSQDDAQAEVERLVREEGLTMVPPFDDPRIIAGQGTIGLEI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 167 IEDLTVtLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGLLTYLG-DK-- 243
Cdd:PRK07476 162 LEALPD-VATVLVPLSGGGLASGVAAAVKAIRPAIRVIGVSMERGAAMHASLAAGRPVQVEEVPTLADSLGGGIGlDNry 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 244 TFPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKKVGIIISGGNVDLG 313
Cdd:PRK07476 241 TFAMCRALLDDVVLLDEAEIAAGIRHAYREERLVVEGAGAVGIAALLAGKIAARDGPIVVVVSGANIDME 310
|
|
| Trp-synth-beta_II |
cd00640 |
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP) ... |
25-308 |
1.07e-68 |
|
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan synthase beta chain (Trp-synth_B), cystathionine beta-synthase (CBS), O-acetylserine sulfhydrylase (CS), serine dehydratase (Ser-dehyd), threonine dehydratase (Thr-dehyd), diaminopropionate ammonia lyase (DAL), and threonine synthase (Thr-synth). ACCD catalyzes the conversion of 1-aminocyclopropane-1-carboxylate to alpha-ketobutyrate and ammonia. Tryptophan synthase folds into a tetramer, where the beta chain is the catalytic PLP-binding subunit and catalyzes the formation of L-tryptophan from indole and L-serine. CBS is a tetrameric hemeprotein that catalyzes condensation of serine and homocysteine to cystathionine. CS is a homodimer that catalyzes the formation of L-cysteine from O-acetyl-L-serine. Ser-dehyd catalyzes the conversion of L- or D-serine to pyruvate and ammonia. Thr-dehyd is active as a homodimer and catalyzes the conversion of L-threonine to 2-oxobutanoate and ammonia. DAL is also a homodimer and catalyzes the alpha, beta-elimination reaction of both L- and D-alpha, beta-diaminopropionate to form pyruvate and ammonia. Thr-synth catalyzes the formation of threonine and inorganic phosphate from O-phosphohomoserine.
Pssm-ID: 107202 [Multi-domain] Cd Length: 244 Bit Score: 214.30 E-value: 1.07e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 25 TPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANG--VITHSSGNHAQAIAFSAQKVGAKCYIVM 102
Cdd:cd00640 1 TPLVRLKRLSKLGGANIYLKLEFLNPTGSFKDRGALNLILLAEEEGKLPKgvIIESTGGNTGIALAAAAARLGLKCTIVM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 103 PDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVART-GATFIHPFNNYEVITGQATAAKELIEDLT-VTLDAIIAP 180
Cdd:cd00640 81 PEGASPEKVAQMRALGAEVVLVPGDFDDAIALAKELAEEDpGAYYVNQFDNPANIAGQGTIGLEILEQLGgQKPDAVVVP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 181 VGGGGLLSGTALSAKYFSPHTQVYAGEPEgaadavlsfrsdkiekapyvntiadglltylgdktfpiikaevtdIFTVSD 260
Cdd:cd00640 161 VGGGGNIAGIARALKELLPNVKVIGVEPE---------------------------------------------VVTVSD 195
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1369174260 261 EEIIQAMRYLWERMKIVVEPSGAVSTAAVLK-NKAVFEGKKVGIIISGG 308
Cdd:cd00640 196 EEALEAIRLLAREEGILVEPSSAAALAAALKlAKKLGKGKTVVVILTGG 244
|
|
| ilvA_2Cterm |
TIGR01124 |
threonine ammonia-lyase, biosynthetic, long form; This model describes a form of threonine ... |
25-317 |
6.04e-65 |
|
threonine ammonia-lyase, biosynthetic, long form; This model describes a form of threonine ammonia-lyase, a pyridoxal-phosphate dependent enzyme, with two copies of the threonine dehydratase C-terminal domain (pfam00585). Members with known function participate in isoleucine biosynthesis and are inhibited by isoleucine. Alternate name: threonine deaminase, threonine dehydratase. Forms scoring between the trusted and noise cutoff tend to branch with this subgroup of threonine ammonia-lyase phylogenetically but have only a single copy of the C-terminal domain. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130194 [Multi-domain] Cd Length: 499 Bit Score: 212.29 E-value: 6.04e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 25 TPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMPD 104
Cdd:TIGR01124 18 TPLQKAAKLSERLGNRILIKREDLQPVFSFKLRGAYNKMAQLSPEQKARGVIAASAGNHAQGVAFSAARLGLKALIVMPE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 105 NSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKELIEDLTVTLDAIIAPVGGG 184
Cdd:TIGR01124 98 TTPDIKVDAVRGFGGEVVLHGANFDDAKAKAIELSQEKGLTFIHPFDDPLVIAGQGTLALEILRQVANPLDAVFVPVGGG 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 185 GLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGL-LTYLGDKTFPIIKAEVTDIFTVSDEEI 263
Cdd:TIGR01124 178 GLAAGVAALIKQLMPEIKVIGVEPTDSDCMKQALDAGEPVDLDQVGLFADGVaVKRVGDETFRLCQQYLDDIVTVDTDEV 257
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1369174260 264 IQAMRYLWERMKIVVEPSGAVSTAAVLKNKAV--FEGKKVGIIISGGNVDLGRLPF 317
Cdd:TIGR01124 258 CAAIKDLFEDTRAVAEPAGALALAGLKKYVALhgIRGQTLVAILSGANMNFHRLRY 313
|
|
| PRK08246 |
PRK08246 |
serine/threonine dehydratase; |
5-311 |
5.40e-63 |
|
serine/threonine dehydratase;
Pssm-ID: 181319 [Multi-domain] Cd Length: 310 Bit Score: 201.72 E-value: 5.40e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 5 VPTRATIEAAHALVKPYIHHTPVFTSQfLNELSGAELYFKCENLQKIGAFKARGGLNAVLSlsAEQLANGVITHSSGNHA 84
Cdd:PRK08246 4 MITRSDVRAAAQRIAPHIRRTPVLEAD-GAGFGPAPVWLKLEHLQHTGSFKARGAFNRLLA--APVPAAGVVAASGGNAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 85 QAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAK 164
Cdd:PRK08246 81 LAVAYAAAALGVPATVFVPETAPPAKVARLRALGAEVVVVGAEYADALEAAQAFAAETGALLCHAYDQPEVLAGAGTLGL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 165 ELIEDLTvTLDAIIAPVGGGGLLSGTALsakYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPyVNTIADGLL--TYLGD 242
Cdd:PRK08246 161 EIEEQAP-GVDTVLVAVGGGGLIAGIAA---WFEGRARVVAVEPEGAPTLHAALAAGEPVDVP-VSGIAADSLgaRRVGE 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 243 KTFPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFE-GKKVGIIISGGNVD 311
Cdd:PRK08246 236 IAFALARAHVVTSVLVSDEAIIAARRALWEELRLAVEPGAATALAALLSGAYVPApGERVAVVLCGANTD 305
|
|
| PRK09224 |
PRK09224 |
threonine ammonia-lyase IlvA; |
24-317 |
8.66e-62 |
|
threonine ammonia-lyase IlvA;
Pssm-ID: 236417 [Multi-domain] Cd Length: 504 Bit Score: 204.22 E-value: 8.66e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 24 HTPVftsQFLNELS---GAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQAIAFSAQKVGAKCYI 100
Cdd:PRK09224 20 ETPL---EKAPKLSarlGNQVLLKREDLQPVFSFKLRGAYNKMAQLTEEQLARGVITASAGNHAQGVALSAARLGIKAVI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 101 VMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKELIEDLTVTLDAIIAP 180
Cdd:PRK09224 97 VMPVTTPDIKVDAVRAFGGEVVLHGDSFDEAYAHAIELAEEEGLTFIHPFDDPDVIAGQGTIAMEILQQHPHPLDAVFVP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 181 VGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGL-LTYLGDKTFPIIKAEVTDIFTVS 259
Cdd:PRK09224 177 VGGGGLIAGVAAYIKQLRPEIKVIGVEPEDSACLKAALEAGERVDLPQVGLFADGVaVKRIGEETFRLCQEYVDDVITVD 256
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1369174260 260 DEEIIQAMRYLWERMKIVVEPSGAVSTAAvLKnKAVF----EGKKVGIIISGGNVDLGRLPF 317
Cdd:PRK09224 257 TDEICAAIKDVFEDTRSIAEPAGALALAG-LK-KYVAqhgiEGETLVAILSGANMNFDRLRY 316
|
|
| PRK12483 |
PRK12483 |
threonine dehydratase; Reviewed |
1-317 |
1.85e-56 |
|
threonine dehydratase; Reviewed
Pssm-ID: 237111 [Multi-domain] Cd Length: 521 Bit Score: 190.78 E-value: 1.85e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 1 MTGTVPTRATIEAAHALVKPYIH------------HTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSA 68
Cdd:PRK12483 2 APTEAVSPTTIAPRAALLADYLRkilaarvydvarETPLQRAPNLSARLGNQVLLKREDLQPVFSFKIRGAYNKMARLPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 69 EQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIH 148
Cdd:PRK12483 82 EQLARGVITASAGNHAQGVALAAARLGVKAVIVMPRTTPQLKVDGVRAHGGEVVLHGESFPDALAHALKLAEEEGLTFVP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 149 PFNNYEVITGQATAAKELIEDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPY 228
Cdd:PRK12483 162 PFDDPDVIAGQGTVAMEILRQHPGPLDAIFVPVGGGGLIAGIAAYVKYVRPEIKVIGVEPDDSNCLQAALAAGERVVLGQ 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 229 VNTIADGL-LTYLGDKTFPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK--NKAVFEGKKVGIII 305
Cdd:PRK12483 242 VGLFADGVaVAQIGEHTFELCRHYVDEVVTVSTDELCAAIKDIYDDTRSITEPAGALAVAGIKKyaEREGIEGQTLVAID 321
|
330
....*....|..
gi 1369174260 306 SGGNVDLGRLPF 317
Cdd:PRK12483 322 SGANVNFDRLRH 333
|
|
| PLN02550 |
PLN02550 |
threonine dehydratase |
3-315 |
3.06e-51 |
|
threonine dehydratase
Pssm-ID: 178165 [Multi-domain] Cd Length: 591 Bit Score: 178.19 E-value: 3.06e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 3 GTVPTRATIEAAHALVKPYIHHTPVFTS-----------QFLNELS---GAELYFKCENLQKIGAFKARGGLNAVLSLSA 68
Cdd:PLN02550 74 GAVPERTNEAENGSIPEAMEYLTNILSAkvydvaiesplQLAKKLSerlGVKVLLKREDLQPVFSFKLRGAYNMMAKLPK 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 69 EQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIH 148
Cdd:PLN02550 154 EQLDKGVICSSAGNHAQGVALSAQRLGCDAVIAMPVTTPEIKWQSVERLGATVVLVGDSYDEAQAYAKQRALEEGRTFIP 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 149 PFNNYEVITGQATAAKELIEDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPY 228
Cdd:PLN02550 234 PFDHPDVIAGQGTVGMEIVRQHQGPLHAIFVPVGGGGLIAGIAAYVKRVRPEVKIIGVEPSDANAMALSLHHGERVMLDQ 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 229 VNTIADGL-LTYLGDKTFPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTA---AVLKNKAVfEGKKVGII 304
Cdd:PLN02550 314 VGGFADGVaVKEVGEETFRLCRELVDGVVLVSRDAICASIKDMFEEKRSILEPAGALALAgaeAYCKYYGL-KDENVVAI 392
|
330
....*....|.
gi 1369174260 305 ISGGNVDLGRL 315
Cdd:PLN02550 393 TSGANMNFDRL 403
|
|
| PRK06110 |
PRK06110 |
threonine dehydratase; |
6-315 |
1.24e-48 |
|
threonine dehydratase;
Pssm-ID: 235699 Cd Length: 322 Bit Score: 165.17 E-value: 1.24e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 6 PTRATIEAAHALVKPYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQ-LANGVITHSSGNHA 84
Cdd:PRK06110 3 FTLAELEAAAAVVYAAMPPTPQYRWPLLAERLGCEVWVKHENHTPTGAFKVRGGLVYFDRLARRGpRVRGVISATRGNHG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 85 QAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGAT-ITFCKNTPEDRQgTVDEIVARTGATFIHPFNNyEVITGQATAA 163
Cdd:PRK06110 83 QSVAFAARRHGLAATIVVPHGNSVEKNAAMRALGAElIEHGEDFQAARE-EAARLAAERGLHMVPSFHP-DLVRGVATYA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 164 KELIEDLTvTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGLLTYLGDK 243
Cdd:PRK06110 161 LELFRAVP-DLDVVYVPIGMGSGICGAIAARDALGLKTRIVGVVSAHAPAYALSFEAGRVVTTPVATTLADGMACRTPDP 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1369174260 244 T-FPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKKVGIIISGGNVDLGRL 315
Cdd:PRK06110 240 EaLEVIRAGADRIVRVTDDEVAAAMRAYFTDTHNVAEGAGAAALAAALQERERLAGKRVGLVLSGGNIDRAVF 312
|
|
| PRK08813 |
PRK08813 |
threonine dehydratase; Provisional |
9-315 |
4.27e-44 |
|
threonine dehydratase; Provisional
Pssm-ID: 236339 [Multi-domain] Cd Length: 349 Bit Score: 154.01 E-value: 4.27e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 9 ATIEAAHALVKPYIHHTPVFTSQFLNelsgaeLYFKCENLQKIGAFKARGGLNAVLSLSAEQLANGVITHSSGNHAQAIA 88
Cdd:PRK08813 24 ADVLAAQARLRRYLSPTPLHYAERFG------VWLKLENLQRTGSYKVRGALNALLAGLERGDERPVICASAGNHAQGVA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 89 FSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKELIE 168
Cdd:PRK08813 98 WSAYRLGVQAITVMPHGAPQTKIAGVAHWGATVRQHGNSYDEAYAFARELADQNGYRFLSAFDDPDVIAGQGTVGIELAA 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 169 DLTvtlDAIIAPVGGGGLLSGTALSAKyfSPHTQVYAGEPEGAADAVLSFRSDKIEKAPyVNTIADGLLTYL-GDKTFPI 247
Cdd:PRK08813 178 HAP---DVVIVPIGGGGLASGVALALK--SQGVRVVGAQVEGVDSMARAIRGDLREIAP-VATLADGVKVKIpGFLTRRL 251
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1369174260 248 IKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKnkavFEGKKVGIIISGGNVDLGRL 315
Cdd:PRK08813 252 CSSLLDDVVIVREAELRETLVRLALEEHVIAEGAGALALAAGRR----VSGKRKCAVVSGGNIDATVL 315
|
|
| Thr-synth_1 |
cd01563 |
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last ... |
25-291 |
7.91e-36 |
|
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants, OPH is an intermediate between the methionine and threonine/isoleucine pathways. Thus threonine synthase competes for OPH with cystathionine-gamma-synthase, the first enzyme in the methionine pathway. These enzymes are in general dimers. Members of this CD, Thr-synth_1, are widely distributed in bacteria, archaea and higher plants.
Pssm-ID: 107206 [Multi-domain] Cd Length: 324 Bit Score: 131.56 E-value: 7.91e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 25 TPVFTSQFLNELSGA-ELYFKCENLQKIGAFKARGGLNAVlSLSAEQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMP 103
Cdd:cd01563 23 TPLVRAPRLGERLGGkNLYVKDEGLNPTGSFKDRGMTVAV-SKAKELGVKAVACASTGNTSASLAAYAARAGIKCVVFLP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 104 DNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEvITGQATAAKELIEDLTVTL-DAIIAPVG 182
Cdd:cd01563 102 AGKALGKLAQALAYGATVLAVEGNFDDALRLVRELAEENWIYLSNSLNPYR-LEGQKTIAFEIAEQLGWEVpDYVVVPVG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 183 GGGLLSGTALSAKYFspHTQ--------VYAGEPEGAADAVLSFRS--DKIEKAPYVNTIADGLltYLGD-----KTFPI 247
Cdd:cd01563 181 NGGNITAIWKGFKEL--KELglidrlprMVGVQAEGAAPIVRAFKEgkDDIEPVENPETIATAI--RIGNpasgpKALRA 256
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1369174260 248 IKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK 291
Cdd:cd01563 257 VRESGGTAVAVSDEEILEAQKLLARTEGIFVEPASAASLAGLKK 300
|
|
| L-Ser-dehyd |
cd06448 |
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the ... |
24-309 |
1.20e-34 |
|
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- , D-serine, or L-threonine to pyruvate/ketobutyrate and ammonia.
Pssm-ID: 107209 Cd Length: 316 Bit Score: 128.19 E-value: 1.20e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 24 HTPVFTSQFLNELSGAELYFKCENLQKIGAFKARgGLNAVLSLSAEQLANG---VITHSSGNHAQAIAFSAQKVGAKCYI 100
Cdd:cd06448 1 KTPLIESTALSKTAGCNVFLKLENLQPSGSFKIR-GIGHLCQKSAKQGLNEcvhVVCSSGGNAGLAAAYAARKLGVPCTI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 101 VMPDNSPKVKIAAVEGYGAT-ITFCKNTPEDRQGTVDEIVAR-TGATFIHPFNNYEVITGQATAAKELIEDL--TVTLDA 176
Cdd:cd06448 80 VVPESTKPRVVEKLRDEGATvVVHGKVWWEADNYLREELAENdPGPVYVHPFDDPLIWEGHSSMVDEIAQQLqsQEKVDA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 177 IIAPVGGGGLLSGTALS-AKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGL-LTYLGDKTFPIIKAEVTD 254
Cdd:cd06448 160 IVCSVGGGGLLNGIVQGlERNGWGDIPVVAVETEGAHSLNASLKAGKLVTLPKITSVATSLgAKTVSSQALEYAQEHNIK 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1369174260 255 IFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAV-----LKNKAVFE---GKKVGIIISGGN 309
Cdd:cd06448 240 SEVVSDRDAVQACLRFADDERILVEPACGAALAVVysgkiLDLQLEVLltpLDNVVVVVCGGS 302
|
|
| ThrC |
COG0498 |
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the ... |
25-291 |
1.60e-31 |
|
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 440264 [Multi-domain] Cd Length: 394 Bit Score: 121.46 E-value: 1.60e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 25 TPVFTSQFLNELSGAELYFKCENLQKIGAFKARGgLNAVLSLSAEQLANGVITHSSGNHAQAIA-FSAqKVGAKCYIVMP 103
Cdd:COG0498 67 TPLVKAPRLADELGKNLYVKEEGHNPTGSFKDRA-MQVAVSLALERGAKTIVCASSGNGSAALAaYAA-RAGIEVFVFVP 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 104 -DNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVItGQATAAKELIEDLTVTLDAIIAPVG 182
Cdd:COG0498 145 eGKVSPGQLAQMLTYGAHVIAVDGNFDDAQRLVKELAADEGLYAVNSINPARLE-GQKTYAFEIAEQLGRVPDWVVVPTG 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 183 GGGLLSGTALSAK------YFSPHTQVYAGEPEGAADAVLSFRSDKIEKAP-YVNTIADGL---LTYLGDKTFPIIKAEV 252
Cdd:COG0498 224 NGGNILAGYKAFKelkelgLIDRLPRLIAVQATGCNPILTAFETGRDEYEPeRPETIAPSMdigNPSNGERALFALRESG 303
|
250 260 270
....*....|....*....|....*....|....*....
gi 1369174260 253 TDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK 291
Cdd:COG0498 304 GTAVAVSDEEILEAIRLLARREGIFVEPATAVAVAGLRK 342
|
|
| CBS_like |
cd01561 |
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS ... |
24-291 |
1.40e-26 |
|
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.
Pssm-ID: 107204 [Multi-domain] Cd Length: 291 Bit Score: 106.06 E-value: 1.40e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 24 HTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSlsAEqlANGVITH-------SSGNHAQAIAFSAQKVGA 96
Cdd:cd01561 2 NTPLVRLNRLSPGTGAEIYAKLEFFNPGGSVKDRIALYMIED--AE--KRGLLKPgttiiepTSGNTGIGLAMVAAAKGY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 97 KCYIVMPDNSPKVKIAAVEGYGATITFC----KNTPEDRQGTVDEIVART-GATFIHPFNN-------YEvitgqaTAAK 164
Cdd:cd01561 78 RFIIVMPETMSEEKRKLLRALGAEVILTpeaeADGMKGAIAKARELAAETpNAFWLNQFENpanpeahYE------TTAP 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 165 ELIEDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAadAVLSFRSD---KIE--KAPYVNTIADGLLty 239
Cdd:cd01561 152 EIWEQLDGKVDAFVAGVGTGGTITGVARYLKEKNPNVRIVGVDPVGS--VLFSGGPPgphKIEgiGAGFIPENLDRSL-- 227
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1369174260 240 lgdktfpiikaeVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK 291
Cdd:cd01561 228 ------------IDEVVRVSDEEAFAMARRLAREEGLLVGGSSGAAVAAALK 267
|
|
| CysK |
COG0031 |
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the ... |
22-301 |
1.35e-24 |
|
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the Pathway/BioSystem: Cysteine biosynthesis
Pssm-ID: 439802 [Multi-domain] Cd Length: 301 Bit Score: 100.89 E-value: 1.35e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 22 IHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSlsAEqlANGVITH-------SSGNHAQAIAFSAQKV 94
Cdd:COG0031 11 IGNTPLVRLNRLSPGPGAEIYAKLESFNPGGSVKDRIALSMIED--AE--KRGLLKPggtiveaTSGNTGIGLAMVAAAK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 95 GAKCYIVMPDNSPKVKIAAVEGYGATITFCKNT--PEDRQGTVDEIVART-GATFIHPFNN-------YEvitgqaTAAK 164
Cdd:COG0031 87 GYRLILVMPETMSKERRALLRAYGAEVVLTPGAegMKGAIDKAEELAAETpGAFWPNQFENpanpeahYE------TTGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 165 ELIEDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAadAVLS---FRSDKIEKapyvntIADGLLTylg 241
Cdd:COG0031 161 EIWEQTDGKVDAFVAGVGTGGTITGVGRYLKERNPDIKIVAVEPEGS--PLLSggePGPHKIEG------IGAGFVP--- 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1369174260 242 dktfPIIKAEVTD-IFTVSDEEIIQAMRYLWERMKIVVEPS-GAVSTAAVLKNKAVFEGKKV 301
Cdd:COG0031 230 ----KILDPSLIDeVITVSDEEAFAMARRLAREEGILVGISsGAAVAAALRLAKRLGPGKTI 287
|
|
| cysK |
TIGR01139 |
cysteine synthase A; This model distinguishes cysteine synthase A (CysK) from cysteine ... |
22-305 |
1.49e-21 |
|
cysteine synthase A; This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family]
Pssm-ID: 273465 Cd Length: 298 Bit Score: 92.43 E-value: 1.49e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 22 IHHTPVFTsqfLNELSG--AELYFKCENLQKIGAFKARGGLNAVLSlsAEQ---LANGV--ITHSSGNHAQAIAFSAQKV 94
Cdd:TIGR01139 5 IGNTPLVR---LNRIEGcnANVFVKLEGRNPSGSVKDRIALNMIWD--AEKrglLKPGKtiVEPTSGNTGIALAMVAAAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 95 GAKCYIVMPDNSPKVKIAAVEGYGATITFcknTP--EDRQGTVD---EIVARTGATFIHP--FNN-YEVITGQATAAKEL 166
Cdd:TIGR01139 80 GYKLILTMPETMSIERRKLLKAYGAELVL---TPgaEGMKGAIAkaeEIAASTPNSYFMLqqFENpANPEIHRKTTGPEI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 167 IEDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAadAVLSfrsdKIEKAPY-VNTIADGLLTylgdktf 245
Cdd:TIGR01139 157 WRDTDGKLDAFVAGVGTGGTITGVGEVLKEQKPNIKIVAVEPAES--PVLS----GGKPGPHkIQGIGAGFIP------- 223
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1369174260 246 PIIKAEVTD-IFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK-NKAVFEGKKVGIII 305
Cdd:TIGR01139 224 KNLNRSVIDeVITVSDEEAIETARRLAAEEGILVGISSGAAVAAALKlAKRPEPDKLIVVIL 285
|
|
| cysKM |
TIGR01136 |
cysteine synthase; This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and ... |
21-305 |
1.02e-19 |
|
cysteine synthase; This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family]
Pssm-ID: 273463 Cd Length: 299 Bit Score: 87.34 E-value: 1.02e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 21 YIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSlsAEQlaNGVITH-------SSGNHAQAIAFSAQK 93
Cdd:TIGR01136 4 LIGNTPLVRLNRLAPGCDARVLAKLEGFNPSGSVKDRIALSMILD--AEK--RGLLKPgdtiieaTSGNTGIALAMVAAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 94 VGAKCYIVMPDNSPKVKIAAVEGYGATITFckNTPEDR-QGTVD---EIVARTGATFI-HPFNN-YEVITGQATAAKELI 167
Cdd:TIGR01136 80 RGYKLILTMPETMSLERRKLLRAYGAELIL--TPGEEGmKGAIDkaeELAAETNKYVMlDQFENpANPEAHYKTTGPEIW 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 168 EDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAadAVLSfrsdKIEKAPY-VNTIADGLLTYLGDKTFp 246
Cdd:TIGR01136 158 RDTDGRIDHFVAGVGTGGTITGVGRYLKEQNPNIQIVAVEPAES--PVLS----GGEPGPHkIQGIGAGFIPKILDLSL- 230
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1369174260 247 iikaeVTDIFTVSDEEIIQAMRYLWERMKIVVEPS--GAVSTAAVLKNKAVFEGKKVGIII 305
Cdd:TIGR01136 231 -----IDEVITVSDEDAIETARRLAREEGILVGISsgAAVAAALKLAKRLENADKVIVAIL 286
|
|
| PRK08329 |
PRK08329 |
threonine synthase; Validated |
18-312 |
2.41e-19 |
|
threonine synthase; Validated
Pssm-ID: 236244 [Multi-domain] Cd Length: 347 Bit Score: 87.19 E-value: 2.41e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 18 VKPYIHHTPVfTSQFLNELS---------GAELYFKCENLQKIGAFKARGGLNAVLSLSAEQLaNGVITHSSGNHAQAIA 88
Cdd:PRK08329 43 MRRYIDYLPV-DEEFLPHLTppitptvkrSIKVYFKLDYLQPTGSFKDRGTYVTVAKLKEEGI-NEVVIDSSGNAALSLA 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 89 FSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNtpeDRQGTVDEIVA---RTGATFI-HPFNNYeVITGQATAAK 164
Cdd:PRK08329 121 LYSLSEGIKVHVFVSYNASKEKISLLSRLGAELHFVEG---DRMEVHEEAVKfskRNNIPYVsHWLNPY-FLEGTKTIAY 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 165 ELIEDLTVTlDAIIAPVGgggllSGTALSAKYFSPHTQVYAGE----PEGAADAVLSFRSdKIEKAPYVNTIADGLLT-- 238
Cdd:PRK08329 197 EIYEQIGVP-DYAFVPVG-----SGTLFLGIWKGFKELHEMGEiskmPKLVAVQAEGYES-LCKRSKSENKLADGIAIpe 269
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1369174260 239 -YLGDKTFPIIKAEVTDIFTVSDEEIIQAMRYLWeRMKIVVEPSGAVSTAAV--LKNKAVFE-GKKVGIIISGGNVDL 312
Cdd:PRK08329 270 pPRKEEMLRALEESNGFCISVGEEETRAALHWLR-RMGFLVEPTSAVALAAYwkLLEEGLIEgGSKVLLPLSGSGLKN 346
|
|
| thrC |
TIGR00260 |
threonine synthase; Involved in threonine biosynthesis it catalyses the reaction ... |
25-291 |
2.02e-17 |
|
threonine synthase; Involved in threonine biosynthesis it catalyses the reaction O-PHOSPHO-L-HOMOSERINE + H(2)O = L-THREONINE + ORTHOPHOSPHATE using pyridoxal phosphate as a cofactor. the enzyme is distantly related to the serine/threonine dehydratases which are also pyridoxal-phosphate dependent enzymes. the pyridoxal-phosphate binding site is a Lys (K) residues present at residue 70 of the model. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 272986 [Multi-domain] Cd Length: 327 Bit Score: 81.27 E-value: 2.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 25 TPVFTSQFLNE-LSGAELYFKCENLQKIGAFKARGGLNAVlSLSAEQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMP 103
Cdd:TIGR00260 23 TPLFRAPALAAnVGIKNLYVKELGHNPTLSFKDRGMAVAL-TKALELGNDTVLCASTGNTGAAAAAYAGKAGLKVVVLYP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 104 -DNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVartGATFIHPFNNYEV----ITGQATAAKELIEDLTVTL-DAI 177
Cdd:TIGR00260 102 aGKISLGKLAQALGYNAEVVAIDGNFDDAQRLVKQLF---EDKPALGLNSANSipyrLEGQKTYAFEAVEQLGWEApDKV 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 178 IAPVGGGGLLsgTALSAKYFSPHTQVYAGEP-------EGAADAVLSFR-SDKIEKAPYVNTIA---DGLLTYLGDKTFP 246
Cdd:TIGR00260 179 VVPVPNSGNF--GAIWKGFKEKKMLGLDSLPvkrgiqaEGAADIVRAFLeGGQWEPIETPETLStamDIGNPANWPRALE 256
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1369174260 247 IIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK 291
Cdd:TIGR00260 257 AFRRSNGYAEDLSDEEILEAIKLLAREEGYFVEPHSAVAVAALLK 301
|
|
| PRK06450 |
PRK06450 |
threonine synthase; Validated |
20-293 |
9.80e-16 |
|
threonine synthase; Validated
Pssm-ID: 180565 [Multi-domain] Cd Length: 338 Bit Score: 76.70 E-value: 9.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 20 PYIHH--------TPVFtsqflnelSGAELYFKCENLQKIGAFKARGGLnAVLSLSAEQLANGVITHSSGNHAQAIAFSA 91
Cdd:PRK06450 46 PYIKHfislgegrTPLI--------KKGNIWFKLDFLNPTGSYKDRGSV-TLISYLAEKGIKQISEDSSGNAGASIAAYG 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 92 QKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPfnnyEVITGQATAAKELIEDLT 171
Cdd:PRK06450 117 AAAGIEVKIFVPETASGGKLKQIESYGAEVVRVRGSREDVAKAAENSGYYYASHVLQP----QFRDGIRTLAYEIAKDLD 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 172 VTL-DAIIAPVGGGGLLSGT------ALSAKYFSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVNTIADGLLT---YLG 241
Cdd:PRK06450 193 WKIpNYVFIPVSAGTLLLGVysgfkhLLDSGVISEMPKIVAVQTEQVSPLCAKFKGISYTPPDKVTSIADALVStrpFLL 272
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1369174260 242 DKTFPIIKaEVTDIFTVSDEEIIQAMRYLwERMKIVVEPSGAVSTAAVLKNK 293
Cdd:PRK06450 273 DYMVKALS-EYGECIVVSDNEIVEAWKEL-AKKGLLVEYSSATVYAAYKKYS 322
|
|
| PRK08197 |
PRK08197 |
threonine synthase; Validated |
35-289 |
5.89e-15 |
|
threonine synthase; Validated
Pssm-ID: 181283 [Multi-domain] Cd Length: 394 Bit Score: 74.65 E-value: 5.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 35 ELSGAELYFKCENLQKIGAFKARGGLNAVlSLSAEQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMPDNSPKVKIAAV 114
Cdd:PRK08197 91 ALGIGRLWVKDEGLNPTGSFKARGLAVGV-SRAKELGVKHLAMPTNGNAGAAWAAYAARAGIRATIFMPADAPEITRLEC 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 115 EGYGATITFCKNTPEDRQGTVDEIVARTG----ATFIHPFNnyevITGQATAAKELIEDLTVTL-DAIIAPVGGGGLLSG 189
Cdd:PRK08197 170 ALAGAELYLVDGLISDAGKIVAEAVAEYGwfdvSTLKEPYR----IEGKKTMGLELAEQLGWRLpDVILYPTGGGVGLIG 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 190 TAlsaKYF----------SPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVN--TIADGLLT--YLGDktFPIIKA----E 251
Cdd:PRK08197 246 IW---KAFdelealgwigGKRPRLVAVQAEGCAPIVKAWEEGKEESEFWEDahTVAFGIRVpkALGD--FLVLDAvretG 320
|
250 260 270
....*....|....*....|....*....|....*...
gi 1369174260 252 VTDIfTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAV 289
Cdd:PRK08197 321 GCAI-AVSDDAILAAQRELAREEGLFACPEGAATFAAA 357
|
|
| PRK05638 |
PRK05638 |
threonine synthase; Validated |
25-307 |
2.16e-14 |
|
threonine synthase; Validated
Pssm-ID: 235539 [Multi-domain] Cd Length: 442 Bit Score: 73.31 E-value: 2.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 25 TPVFTSQFLNELsGAELYFKCENLQKIGAFKARGGLNAVlSLSAEQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMPD 104
Cdd:PRK05638 67 TPLIRARISEKL-GENVYIKDETRNPTGSFRDRLATVAV-SYGLPYAANGFIVASDGNAAASVAAYSARAGKEAFVVVPR 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 105 NSPKVKIAAVEGYGATITFCKNTPEDRQGTVDEIVARTGATFIHPFNNYEVITGQATAAKELIEDLTVTldAIIAPVGGG 184
Cdd:PRK05638 145 KVDKGKLIQMIAFGAKIIRYGESVDEAIEYAEELARLNGLYNVTPEYNIIGLEGQKTIAFELWEEINPT--HVIVPTGSG 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 185 G-LLSgtalsakyfsphtqVYAGEPEGAADAVLsfrsDKIEKAPYVNT-----IADGLLTYLGDKTF----------PII 248
Cdd:PRK05638 223 SyLYS--------------IYKGFKELLEIGVI----EEIPKLIAVQTercnpIASEILGNKTKCNEtkalglyvknPVM 284
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1369174260 249 KAEVTDIF-------TVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK--NKAVFE-GKKVGIIISG 307
Cdd:PRK05638 285 KEYVSEAIkesggtaVVVNEEEIMAGEKLLAKEGIFAELSSAVVMPALLKlgEEGYIEkGDKVVLVVTG 353
|
|
| PRK06381 |
PRK06381 |
threonine synthase; Validated |
25-308 |
9.45e-13 |
|
threonine synthase; Validated
Pssm-ID: 235789 Cd Length: 319 Bit Score: 67.81 E-value: 9.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 25 TPVFTSQFL-NELSGAELYFKCENLQKIGAFKARGGLNAVLSlSAEQLANGVITHSSGNHAQAIAFSAQKVGAKCYIVMP 103
Cdd:PRK06381 16 TPLLRARKLeEELGLRKIYLKFEGANPTGTQKDRIAEAHVRR-AMRLGYSGITVGTCGNYGASIAYFARLYGLKAVIFIP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 104 DNSPKVKIAAVEGYGATITFCKNTPEDrqgTVDEIV----------ARTGATfihpfNNYEVITGQATAAKELIEDLTVT 173
Cdd:PRK06381 95 RSYSNSRVKEMEKYGAEIIYVDGKYEE---AVERSRkfakengiydANPGSV-----NSVVDIEAYSAIAYEIYEALGDV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 174 LDAIIAPVGGGGLLSG--------------------TALSAKYFSPHTQV-YAGEPEGAADAVLSFRSDKIEKaPYVNTI 232
Cdd:PRK06381 167 PDAVAVPVGNGTTLAGiyhgfrrlydrgktsrmprmIGVSTSGGNQIVESfKRGSSEVVDLEVDEIRETAVNE-PLVSYR 245
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1369174260 233 AdglltYLGDKTFPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAV---LKNKAVFEgkKVGIIISGG 308
Cdd:PRK06381 246 S-----FDGDNALEAIYDSHGYAFGFSDDEMVKYAELLRRMEGLNALPASASALAALvkyLKKNGVND--NVVAVITGR 317
|
|
| PRK08206 |
PRK08206 |
diaminopropionate ammonia-lyase; Provisional |
51-291 |
9.86e-13 |
|
diaminopropionate ammonia-lyase; Provisional
Pssm-ID: 236186 Cd Length: 399 Bit Score: 67.98 E-value: 9.86e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 51 IGAFKARGGLNAVLSLSAEQLANG----------------------VITHSSGNHAQAIAFSAQKVGAKCYIVMPDNSPK 108
Cdd:PRK08206 73 LNAFKALGGAYAVARLLAEKLGLDiselsfeeltsgevreklgditFATATDGNHGRGVAWAAQQLGQKAVIYMPKGSSE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 109 VKIAAVEGYGATIT-----------FCKNTPEDRQGTVDEIVARTGatfihpfnnYE-----VITGQATAAKELIEDLTV 172
Cdd:PRK08206 153 ERVDAIRALGAECIitdgnyddsvrLAAQEAQENGWVVVQDTAWEG---------YEeiptwIMQGYGTMADEAVEQLKE 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 173 TLDA-----IIAPVGGgglLSGTALSakYFS-------PHTQVYagEPEGAADAVLSFRSDKIEKAPY-VNTIADGLLTY 239
Cdd:PRK08206 224 MGVPpthvfLQAGVGS---LAGAVLG--YFAevygeqrPHFVVV--EPDQADCLYQSAVDGKPVAVTGdMDTIMAGLACG 296
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 240 ----LGdktFPIIKAEVTDIFTVSDEEIIQAMRYLWERM----KIVVEPSGAVSTAAVLK 291
Cdd:PRK08206 297 epnpLA---WEILRNCADAFISCPDEVAALGMRILANPLggdpPIVSGESGAVGLGALAA 353
|
|
| PRK10717 |
PRK10717 |
cysteine synthase A; Provisional |
22-315 |
8.31e-12 |
|
cysteine synthase A; Provisional
Pssm-ID: 182672 [Multi-domain] Cd Length: 330 Bit Score: 64.88 E-value: 8.31e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 22 IHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSlsAE---QLANG--VITHSSGNHAQAIAFSAQKVGA 96
Cdd:PRK10717 11 IGNTPLIRLNRASEATGCEILGKAEFLNPGGSVKDRAALNIIWD--AEkrgLLKPGgtIVEGTAGNTGIGLALVAAARGY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 97 KCYIVMPDNSPKVKIAAVEGYGATITFCKNTPEDRQGT--------VDEIVART--GATFIHPFNNyeVITGQA---TAA 163
Cdd:PRK10717 89 KTVIVMPETQSQEKKDLLRALGAELVLVPAAPYANPNNyvkgagrlAEELVASEpnGAIWANQFDN--PANREAhyeTTG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 164 KELIEDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPEGAadAVLSFRSDKIEKAPYvNTIADGLltYLGDK 243
Cdd:PRK10717 167 PEIWEQTDGKVDGFVCAVGTGGTLAGVSRYLKETNPKVKIVLADPTGS--ALYSYYKTGELKAEG-SSITEGI--GQGRI 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1369174260 244 TFPIIKAEVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK-NKAVFEGKK-VGIIISGGNVDLGRL 315
Cdd:PRK10717 242 TANLEGAPIDDAIRIPDEEALSTAYRLLEEEGLCLGGSSGINVAAALRlARELGPGHTiVTILCDSGERYQSKL 315
|
|
| PLN02356 |
PLN02356 |
phosphateglycerate kinase |
1-291 |
5.77e-10 |
|
phosphateglycerate kinase
Pssm-ID: 215204 Cd Length: 423 Bit Score: 60.00 E-value: 5.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 1 MTGTVPTRATIEAahalvkpyIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVL-SLSAEQLA-NGVITH 78
Cdd:PLN02356 38 LSKKKPRNGLIDA--------IGNTPLIRINSLSEATGCEILGKCEFLNPGGSVKDRVAVKIIEeALESGQLFpGGVVTE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 79 -SSGNHAQAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFCK-----------NTPEDRQGTVDEIVAR----- 141
Cdd:PLN02356 110 gSAGSTAISLATVAPAYGCKCHVVIPDDVAIEKSQILEALGATVERVRpvsithkdhyvNIARRRALEANELASKrrkgs 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 142 ----------------------------TGATFIHPFNNYEVITGQATA-AKELIEDLTVTLDAIIAPVGGGGLLSGTAL 192
Cdd:PLN02356 190 etdgihlektngciseeekenslfssscTGGFFADQFENLANFRAHYEGtGPEIWEQTQGNLDAFVAAAGTGGTLAGVSR 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 193 SAKYFSPHTQVYAGEPEGAA------DAVLSFRSD---KIEKAPYvNTIADGLLTYLGDKTFpiIKAEVTDIFTVSDEEI 263
Cdd:PLN02356 270 FLQEKNPNIKCFLIDPPGSGlfnkvtRGVMYTREEaegRRLKNPF-DTITEGIGINRLTQNF--LMAKLDGAFRGTDKEA 346
|
330 340
....*....|....*....|....*...
gi 1369174260 264 IQAMRYLWERMKIVVEPSGAVSTAAVLK 291
Cdd:PLN02356 347 VEMSRYLLKNDGLFVGSSSAMNCVGAVR 374
|
|
| D-Ser-dehyd |
cd06447 |
D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the ... |
40-300 |
2.31e-08 |
|
D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine to pyruvate and ammonia. D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive antagonist of beta-alanine in the biosynthetic pathway to pentothenate and coenzyme A. D-serine dehydratase is different from other pyridoxal-5'-phosphate-dependent enzymes in that it catalyzes alpha, beta-elimination reactions on amino acids.
Pssm-ID: 107208 Cd Length: 404 Bit Score: 54.66 E-value: 2.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 40 ELYFKCENLQKI-GAFKARGGLNAVLSLsAEQLA--NGVITH------------------------SSGNHAQAIAFSAQ 92
Cdd:cd06447 76 RLLLKADSHLPIsGSIKARGGIYEVLKH-AEKLAleHGLLTLeddysklasekfrklfsqysiavgSTGNLGLSIGIMAA 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 93 KVGAKCYIVMPDNSPKVKIAAVEGYGATIT-----FCKNTPEDRQGTVdeivARTGATFIHPFNNYEVITGQATAAKEL- 166
Cdd:cd06447 155 ALGFKVTVHMSADAKQWKKDKLRSKGVTVVeyetdYSKAVEEGRKQAA----ADPMCYFVDDENSRDLFLGYAVAASRLk 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 167 --IEDLTVTLDA-----IIAPVGGGGLLSGTALSAKY-FSPHTQVYAGEPEGAADAVLSFRSDKIEKAPYVN------TI 232
Cdd:cd06447 231 aqLAELGIKVDAehplfVYLPCGVGGAPGGVAFGLKLiFGDNVHCFFAEPTHSPCMLLGMATGLHDKISVQDigidnrTA 310
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1369174260 233 ADGLLT-----YLGDKTFPIIKAevtdIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLKNKAVFEGKK 300
Cdd:cd06447 311 ADGLAVgrpsgLVGKLMEPLLSG----IYTVEDDELYRLLAMLKDSENIEVEPSAAAGFTGPAQVLSEAEGKR 379
|
|
| PLN00011 |
PLN00011 |
cysteine synthase |
75-291 |
4.08e-05 |
|
cysteine synthase
Pssm-ID: 177651 Cd Length: 323 Bit Score: 44.61 E-value: 4.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 75 VITHSSGNHAQAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFcKNTPEDRQGTVD---EIVART-GATFIHPF 150
Cdd:PLN00011 72 LIEATAGNTGIGLACIGAARGYKVILVMPSTMSLERRIILRALGAEVHL-TDQSIGLKGMLEkaeEILSKTpGGYIPQQF 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 151 NNYE-VITGQATAAKELIEDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPegAADAVLSfrsdKIEKAPY- 228
Cdd:PLN00011 151 ENPAnPEIHYRTTGPEIWRDSAGKVDILVAGVGTGGTATGVGKFLKEKNKDIKVCVVEP--VESAVLS----GGQPGPHl 224
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1369174260 229 VNTIADGLLTYLGDKTFpiikaeVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK 291
Cdd:PLN00011 225 IQGIGSGIIPFNLDLTI------VDEIIQVTGEEAIETAKLLALKEGLLVGISSGAAAAAALK 281
|
|
| PLN02556 |
PLN02556 |
cysteine synthase/L-3-cyanoalanine synthase |
22-208 |
4.16e-05 |
|
cysteine synthase/L-3-cyanoalanine synthase
Pssm-ID: 178171 [Multi-domain] Cd Length: 368 Bit Score: 44.57 E-value: 4.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 22 IHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSLSAEQL----ANGVITHSSGNHAQAIAFSAQKVGAK 97
Cdd:PLN02556 57 IGKTPLVYLNKVTEGCGAYIAAKQEMFQPTSSIKDRPALAMIEDAEKKNLitpgKTTLIEPTSGNMGISLAFMAAMKGYK 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 98 CYIVMPDNSPKVKIAAVEGYGATITFCKNTpEDRQGTVD---EIVART-GATFIHPFNN-YEVITGQATAAKELIEDLTV 172
Cdd:PLN02556 137 MILTMPSYTSLERRVTMRAFGAELVLTDPT-KGMGGTVKkayELLESTpDAFMLQQFSNpANTQVHFETTGPEIWEDTLG 215
|
170 180 190
....*....|....*....|....*....|....*.
gi 1369174260 173 TLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEP 208
Cdd:PLN02556 216 QVDIFVMGIGSGGTVSGVGKYLKSKNPNVKIYGVEP 251
|
|
| PLN03013 |
PLN03013 |
cysteine synthase |
18-291 |
4.74e-05 |
|
cysteine synthase
Pssm-ID: 178587 [Multi-domain] Cd Length: 429 Bit Score: 44.77 E-value: 4.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 18 VKPYIHHTPVFtsqFLNELSG---AELYFKCENLQKIGAFKARGGLNAVLSlsAEQ---LANG---VITHSSGNHAQAIA 88
Cdd:PLN03013 117 VSQLIGKTPMV---YLNSIAKgcvANIAAKLEIMEPCCSVKDRIGYSMVTD--AEQkgfISPGksvLVEPTSGNTGIGLA 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 89 FSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATITFcKNTPEDRQGTV---DEIVART-GATFIHPFNN-------YEvit 157
Cdd:PLN03013 192 FIAASRGYRLILTMPASMSMERRVLLKAFGAELVL-TDPAKGMTGAVqkaEEILKNTpDAYMLQQFDNpanpkihYE--- 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 158 gqaTAAKELIEDLTVTLDAIIAPVGGGGLLSGTALSAKYFSPHTQVYAGEPegAADAVLSFRSDKIEKapyVNTIADGLL 237
Cdd:PLN03013 268 ---TTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEP--TESDILSGGKPGPHK---IQGIGAGFI 339
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1369174260 238 TYLGDKTFpiikaeVTDIFTVSDEEIIQAMRYLWERMKIVVEPSGAVSTAAVLK 291
Cdd:PLN03013 340 PKNLDQKI------MDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIK 387
|
|
| cysM |
PRK11761 |
cysteine synthase CysM; |
9-122 |
1.53e-04 |
|
cysteine synthase CysM;
Pssm-ID: 236972 Cd Length: 296 Bit Score: 42.55 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 9 ATIEAahalvkpYIHHTPVFTSQFLNELSGAELYFKCENLQKIGAFKARGGLNAVLSlsAEQ---LANG--VITHSSGNH 83
Cdd:PRK11761 4 PTLED-------TIGNTPLVKLQRLPPDRGNTILAKLEGNNPAGSVKDRPALSMIVQ--AEKrgeIKPGdtLIEATSGNT 74
|
90 100 110
....*....|....*....|....*....|....*....
gi 1369174260 84 AQAIAFSAQKVGAKCYIVMPDNSPKVKIAAVEGYGATIT 122
Cdd:PRK11761 75 GIALAMIAAIKGYRMKLIMPENMSQERRAAMRAYGAELI 113
|
|
| PLN02565 |
PLN02565 |
cysteine synthase |
39-291 |
3.80e-04 |
|
cysteine synthase
Pssm-ID: 166206 Cd Length: 322 Bit Score: 41.45 E-value: 3.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 39 AELYFKCENLQKIGAFKARGGLNAVLSLSAEQL----ANGVITHSSGNHAQAIAFSAQKVGAKCYIVMPDNSPKVKIAAV 114
Cdd:PLN02565 30 ARIAAKLEMMEPCSSVKDRIGYSMITDAEEKGLikpgESVLIEPTSGNTGIGLAFMAAAKGYKLIITMPASMSLERRIIL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 115 EGYGATITFcKNTPEDRQGTV---DEIVARTGATFI--------HPFNNYEvitgqaTAAKELIEDLTVTLDAIIAPVGG 183
Cdd:PLN02565 110 LAFGAELVL-TDPAKGMKGAVqkaEEILAKTPNSYIlqqfenpaNPKIHYE------TTGPEIWKGTGGKVDAFVSGIGT 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1369174260 184 GGLLSGTALSAKYFSPHTQVYAGEPegAADAVLSFRSDKIEKapyVNTIADGLLTYLGDKTFpiikaeVTDIFTVSDEEI 263
Cdd:PLN02565 183 GGTITGAGKYLKEQNPDIKLYGVEP--VESAVLSGGKPGPHK---IQGIGAGFIPGVLDVDL------LDEVVQVSSDEA 251
|
250 260
....*....|....*....|....*...
gi 1369174260 264 IQAMRYLWERMKIVVEPSGAVSTAAVLK 291
Cdd:PLN02565 252 IETAKLLALKEGLLVGISSGAAAAAAIK 279
|
|
| |
