|
Name |
Accession |
Description |
Interval |
E-value |
| pyru_phos_dikin |
TIGR01828 |
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called ... |
2-860 |
0e+00 |
|
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called pyruvate,orthophosphate dikinase. It is similar in sequence to other PEP-utilizing enzymes. [Energy metabolism, Other]
Pssm-ID: 273822 [Multi-domain] Cd Length: 856 Bit Score: 1351.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 2 TKLIYAFDEGQKSMKDLLGGKGANLSEMKRLGLPVPDGFTITTEACIDYLKQGEHLSDEVKSQLHDHLTAFSNRTGKSFS 81
Cdd:TIGR01828 1 KKRVYAFGEGNASMKNLLGGKGANLAEMTKLGLPVPPGFTITTEACNEYYANGKQFPKGLQEEIKEALTLLEEKTGKKFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 82 SQDHLLLVSVRSGAKISMPGMMDTILNLGLNDENVEKLATKTDDARFAYDCYRRLLQMFGDVVYGVPMTHFDTYFEQYKK 161
Cdd:TIGR01828 81 DTENPLLVSVRSGAAVSMPGMMDTILNLGLNDETVEGLAKLTGNARFAYDSYRRFIQMFGDVVLGIPHELFEQILEAMKE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 162 AHQYNSDADITAEGLKEICEQYKGIYLEHGHKPFPQDPLQQLEESIEAVFKSWDNDRARVYRDLNDIPHDIGTAVNIQEM 241
Cdd:TIGR01828 161 EKGVKLDTDLTADDLKELIEKYKAIYREATGKPFPQDPKEQLELAIKAVFDSWNNPRAIVYRRLNDIPEDWGTAVNIQSM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 242 VFGNSGERSGTGVAFTRNPVTGENQLFGEYLLNAQGEDVVAGIRTPKDIDTLKEQMPDVHQQFVNVTKQLETHYKDLQDI 321
Cdd:TIGR01828 241 VFGNMGETSGTGVAFTRNPSTGEKGLFGEFLINAQGEDVVAGIRTPQPITAMEADMPDVYKELLDIAEKLEGHYRDMQDI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 322 EFTIENGRLYLLQTRNGKRTARAAIKVAVDLVNEGLITKEEAVTQVDVKSIETLLHPNFKEEALKqaTVISKmGLPASPG 401
Cdd:TIGR01828 321 EFTIERGKLYMLQTRNGKRTAKAAVRIAVDMVKEGLITEEEAIMRVEPKSLDQLLHPRFDPSALK--TVLAK-GLPASPG 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 402 AATGKVVFSAEEAKVQAENGDSVILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDVEIDTVNK 481
Cdd:TIGR01828 398 AATGKIVFSAEDAVELAEKGKKVILVREETSPEDIEGMHVAEGILTARGGMTSHAAVVARGMGKCCVSGCEELKINEEAK 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 482 TVHYPnGDMLHEGDIISVDGSAGDLYLGEIETVSAEHSDEFEQFMQWSEEIARLQVRMNAETPQDIQAGYQFNAKGIGLV 561
Cdd:TIGR01828 478 TFTIG-GRVFHEGDIISIDGSTGEIYLGEIPLIEPSVSGDFETIMDWADKIRKLKVRANADTPEDALTARKFGAEGIGLC 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 562 RTEHMFFGAERLVEMRRFILASNYDERVEALNKIKTYQIEDFEAIFKLSSGRPTIVRLLDPPLHEFLPSTEEDIAMVADQ 641
Cdd:TIGR01828 557 RTEHMFFGAERIPAVRKMILADSEEERQKALNKLLPFQKEDFKGLFKAMEGLPVTIRLLDPPLHEFLPHTEELQKELAED 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 642 LNVSTAHLKRRINDLNEVNPMLGHRGCRLAITYPELYEMQVEAIMTSVFNLKKEGITSQPEIMIPLVSTVEEFTTLKSQL 721
Cdd:TIGR01828 637 MGLTLAEILKRVEELHEVNPMLGHRGCRLGITYPEIYEMQVRAIMEAAVEVKKEGIDVHPEIMIPLVGEKNELKILKDVL 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 722 VSTIQDLENDMKDKVHYLIGTMIETPRACLIADQLAQQCDFFSFGTNDLTQLTYGFSRDDAGKFINVYTESNILQLDPFQ 801
Cdd:TIGR01828 717 EEVAAEVFKEYGVTVPYEIGTMIEIPRAALTADKIAEEADFFSFGTNDLTQMTFGFSRDDAGKFLPKYLEKGILEKDPFE 796
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*....
gi 1375050723 802 TLDHDGVGQLIEIAVTNAKRVNSSIKIGVCGELGGDAKSIRRFNQLDIDYVSCSPFRVP 860
Cdd:TIGR01828 797 SLDQTGVGQLMRMAVEKGRQTRPNLKVGICGEHGGDPSSIEFCHKIGLNYVSCSPYRVP 855
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
1-544 |
3.39e-174 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 514.29 E-value: 3.39e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 1 MTKLIYAFDEGQKSMKDLLGGKGANLSEMKRLGLPVPDGFTITTEACIDYLKQGEHLSDEVKSQLHDHLTAFSNRTGKSF 80
Cdd:PRK05878 5 LENAVVLLDGGANQPRELLGGKGHGIDMMRRLGLPVPPAFCITTEVCVRYLADPGSTIDAIWDDVLDRMRWLEAETGRTF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 81 SSQDHLLLVSVRSGAKISMPGMMDTILNLGLNDENVEKLATKTDDARFAYDCYRRLLQMFGDVVygvpmthfdtyfeqyk 160
Cdd:PRK05878 85 GRGPRPLLVSVRSGAAQSMPGMMDTILNLGINDAVEQALAAEGGDPDFAADTRRRFTEMYRRIV---------------- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 161 kahqyNSDADItaeglkeiceqykgiylehghkpfPQDPLQQLEESIEAVFKSWDNDRARVYRDLNDIPHDIGTAVNIQE 240
Cdd:PRK05878 149 -----GSGSPP------------------------PDDPYEQLRAAIEAVFASWNSPRAVAYRRHHGLDDDGGTAVVVQA 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 241 MVFGNSGERSGTGVAFTRNPVTGENQLFGEYLLNAQGEDVVAGIRTPKDIDTLKEQMPDVHQQFVNVTKQLETHYKDLQD 320
Cdd:PRK05878 200 MVFGNLDANSGTGVLFSRNPITGANEPFGEWLPGGQGEDVVSGLVDVAPITALRDEQPAVYDELMAAARTLERLGRDVQD 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 321 IEFTIENGRLYLLQTRNGKRTARAAIKVAVDLVNEGLITKEEAVTQVDVKSIETLLHPNFKEEALKQATVISKmGLPASP 400
Cdd:PRK05878 280 IEFTVESGKLWLLQTRSAKRSAQAAVRLALQLHDEGLIDDAEALRRVTPTHVETLLRPSLQPEARLAAPLLAK-GLPACP 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 401 GAATGKVVFSAEEAKVQAENGDSVILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDveiDTVn 480
Cdd:PRK05878 359 GVVSGTAYTDVDEALDAADRGEPVILVRDHTRPDDVHGMLAAQGIVTEVGGATSHAAVVSRELGRVAVVGCGA---GVA- 434
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1375050723 481 ktvhypngDMLhEGDIISVDGSAGDLYLGEIETVSAEHSD--EFEQFMQWSEEIARLQVRMNAETP 544
Cdd:PRK05878 435 --------AAL-AGKEITVDGYEGEVRQGVLALSAWSESDtpELRELADIAQRISPLRAHASGDYP 491
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-504 |
5.04e-154 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 459.68 E-value: 5.04e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 1 MTKLIYAFDEGQKSMKDLLGGKGANLSEMKRLGLPVPDGFTITTEACIDYLKQGE------------------------- 55
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMTRLGLPVPPGFTITTEAYRRFLEENGleeeirelladldvddvdalaeasa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 56 ---------HLSDEVKSQLHDHLTAFSNRTGKSfssqdhlLLVSVRSGAK------ISMPGMMDTILNLglndenvekla 120
Cdd:COG0574 81 eirelileaPLPEELEEEILAAYAKLEEKFGED-------LLVAVRSSATaedlpdASFAGQMDTVLNV----------- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 121 tktddarfaydcyrrllqmfgdvvygvpmthfdtyfeqykkahqyNSDAditaeglkeiceqykgiylehghkpfpqdpl 200
Cdd:COG0574 143 ---------------------------------------------NGNE------------------------------- 146
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 201 qQLEESIEAVFKSWDNDRARVYRDLNDIPH-DIGTAVNIQEMVFGNsgeRSGTGVAFTRNPVTGEN-QLFGEYLlNAQGE 278
Cdd:COG0574 147 -QLLEAIKAVFASLFTDRAIAYRRHNGIDHdDVGTAVNVQAMVFGN---MSASGVMFTRDPSTGEKdVVYIEAL-NGLGE 221
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 279 DVVAGIRTP------------KDIDTLKEQM----------------------PDVHQQFVNVTKQLETHYKDLQDIEFT 324
Cdd:COG0574 222 DVVAGIVTPdpyyvdkptileRTLGSKAIKMvydggtvevpvppeernrpsltDEEYLELARIALRLEKHYGDPQDIEWA 301
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 325 IENGRLYLLQTRNgkrtaraaIKVAvdlvnEGLITKEeAVTQVDVKSIETLLHPNFKEEALKQATVISKmGLPASPGAAT 404
Cdd:COG0574 302 IDDGKLYILQTRP--------ITVL-----EGLITKE-ALLRVDPAQLDQLLHPRFDPKAKEEGEVLAK-GLPASPGAAS 366
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 405 GKVVFSAEEAK-VQAENGDsvILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDVEidtvnktv 483
Cdd:COG0574 367 GKVVFIADEAElARFQEGV--ILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDAT-------- 436
|
570 580
....*....|....*....|.
gi 1375050723 484 hypngDMLHEGDIISVDGSAG 504
Cdd:COG0574 437 -----RVLKDGDEITVDGTTG 452
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
525-870 |
3.77e-76 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 249.92 E-value: 3.77e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 525 FMQWSEEIARLQVRMNAETPQDIQAGYQFNAKGIGLVRTEHMFFGAERLvemrrfilasnydervealnKIKTYQIEDFE 604
Cdd:pfam02896 10 LPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDEL--------------------PTEDEQFEAYK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 605 AIFKLSSGRPTIVRLLDPPLHEFLPSTEEdiamvadqlnvstahlkrrindLNEVNPMLGHRGCRLAITYPELYEMQVEA 684
Cdd:pfam02896 70 GVLEAMNGRPVTVRTLDIGGDKELPYLEE----------------------PEEMNPFLGWRGIRIGLDRPELFRTQLRA 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 685 ImtsvfnlKKEGITSQPEIMIPLVSTVEEFTTLKSQLVSTIQDLENDMKDKVHYLIGTMIETPRACLIADQLAQQCDFFS 764
Cdd:pfam02896 128 I-------LRASAFGNLRIMFPMVASVEELREAKAIIEEVKEELDAEVGFDKDIKVGIMIEVPSAALLADQLAKEVDFFS 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 765 FGTNDLTQLTYGFSRDDAgKFINVYtesnilqlDPFQTLDHDGVGQLIEIAVTNAKrvnssiKIGVCGELGGDAKSIRRF 844
Cdd:pfam02896 201 IGTNDLTQYTLAVDRDNE-RVAYLY--------DPLHPAVLRLIKEVIRAAHRHGK------WVGICGEMAGDPSAVPLL 265
|
330 340
....*....|....*....|....*.
gi 1375050723 845 NQLDIDYVSCSPFRVPGAILATAQSQ 870
Cdd:pfam02896 266 VGLGLDEFSMSPDSVPRARALLAQID 291
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pyru_phos_dikin |
TIGR01828 |
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called ... |
2-860 |
0e+00 |
|
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called pyruvate,orthophosphate dikinase. It is similar in sequence to other PEP-utilizing enzymes. [Energy metabolism, Other]
Pssm-ID: 273822 [Multi-domain] Cd Length: 856 Bit Score: 1351.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 2 TKLIYAFDEGQKSMKDLLGGKGANLSEMKRLGLPVPDGFTITTEACIDYLKQGEHLSDEVKSQLHDHLTAFSNRTGKSFS 81
Cdd:TIGR01828 1 KKRVYAFGEGNASMKNLLGGKGANLAEMTKLGLPVPPGFTITTEACNEYYANGKQFPKGLQEEIKEALTLLEEKTGKKFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 82 SQDHLLLVSVRSGAKISMPGMMDTILNLGLNDENVEKLATKTDDARFAYDCYRRLLQMFGDVVYGVPMTHFDTYFEQYKK 161
Cdd:TIGR01828 81 DTENPLLVSVRSGAAVSMPGMMDTILNLGLNDETVEGLAKLTGNARFAYDSYRRFIQMFGDVVLGIPHELFEQILEAMKE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 162 AHQYNSDADITAEGLKEICEQYKGIYLEHGHKPFPQDPLQQLEESIEAVFKSWDNDRARVYRDLNDIPHDIGTAVNIQEM 241
Cdd:TIGR01828 161 EKGVKLDTDLTADDLKELIEKYKAIYREATGKPFPQDPKEQLELAIKAVFDSWNNPRAIVYRRLNDIPEDWGTAVNIQSM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 242 VFGNSGERSGTGVAFTRNPVTGENQLFGEYLLNAQGEDVVAGIRTPKDIDTLKEQMPDVHQQFVNVTKQLETHYKDLQDI 321
Cdd:TIGR01828 241 VFGNMGETSGTGVAFTRNPSTGEKGLFGEFLINAQGEDVVAGIRTPQPITAMEADMPDVYKELLDIAEKLEGHYRDMQDI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 322 EFTIENGRLYLLQTRNGKRTARAAIKVAVDLVNEGLITKEEAVTQVDVKSIETLLHPNFKEEALKqaTVISKmGLPASPG 401
Cdd:TIGR01828 321 EFTIERGKLYMLQTRNGKRTAKAAVRIAVDMVKEGLITEEEAIMRVEPKSLDQLLHPRFDPSALK--TVLAK-GLPASPG 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 402 AATGKVVFSAEEAKVQAENGDSVILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDVEIDTVNK 481
Cdd:TIGR01828 398 AATGKIVFSAEDAVELAEKGKKVILVREETSPEDIEGMHVAEGILTARGGMTSHAAVVARGMGKCCVSGCEELKINEEAK 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 482 TVHYPnGDMLHEGDIISVDGSAGDLYLGEIETVSAEHSDEFEQFMQWSEEIARLQVRMNAETPQDIQAGYQFNAKGIGLV 561
Cdd:TIGR01828 478 TFTIG-GRVFHEGDIISIDGSTGEIYLGEIPLIEPSVSGDFETIMDWADKIRKLKVRANADTPEDALTARKFGAEGIGLC 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 562 RTEHMFFGAERLVEMRRFILASNYDERVEALNKIKTYQIEDFEAIFKLSSGRPTIVRLLDPPLHEFLPSTEEDIAMVADQ 641
Cdd:TIGR01828 557 RTEHMFFGAERIPAVRKMILADSEEERQKALNKLLPFQKEDFKGLFKAMEGLPVTIRLLDPPLHEFLPHTEELQKELAED 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 642 LNVSTAHLKRRINDLNEVNPMLGHRGCRLAITYPELYEMQVEAIMTSVFNLKKEGITSQPEIMIPLVSTVEEFTTLKSQL 721
Cdd:TIGR01828 637 MGLTLAEILKRVEELHEVNPMLGHRGCRLGITYPEIYEMQVRAIMEAAVEVKKEGIDVHPEIMIPLVGEKNELKILKDVL 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 722 VSTIQDLENDMKDKVHYLIGTMIETPRACLIADQLAQQCDFFSFGTNDLTQLTYGFSRDDAGKFINVYTESNILQLDPFQ 801
Cdd:TIGR01828 717 EEVAAEVFKEYGVTVPYEIGTMIEIPRAALTADKIAEEADFFSFGTNDLTQMTFGFSRDDAGKFLPKYLEKGILEKDPFE 796
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*....
gi 1375050723 802 TLDHDGVGQLIEIAVTNAKRVNSSIKIGVCGELGGDAKSIRRFNQLDIDYVSCSPFRVP 860
Cdd:TIGR01828 797 SLDQTGVGQLMRMAVEKGRQTRPNLKVGICGEHGGDPSSIEFCHKIGLNYVSCSPYRVP 855
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
1-544 |
3.39e-174 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 514.29 E-value: 3.39e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 1 MTKLIYAFDEGQKSMKDLLGGKGANLSEMKRLGLPVPDGFTITTEACIDYLKQGEHLSDEVKSQLHDHLTAFSNRTGKSF 80
Cdd:PRK05878 5 LENAVVLLDGGANQPRELLGGKGHGIDMMRRLGLPVPPAFCITTEVCVRYLADPGSTIDAIWDDVLDRMRWLEAETGRTF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 81 SSQDHLLLVSVRSGAKISMPGMMDTILNLGLNDENVEKLATKTDDARFAYDCYRRLLQMFGDVVygvpmthfdtyfeqyk 160
Cdd:PRK05878 85 GRGPRPLLVSVRSGAAQSMPGMMDTILNLGINDAVEQALAAEGGDPDFAADTRRRFTEMYRRIV---------------- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 161 kahqyNSDADItaeglkeiceqykgiylehghkpfPQDPLQQLEESIEAVFKSWDNDRARVYRDLNDIPHDIGTAVNIQE 240
Cdd:PRK05878 149 -----GSGSPP------------------------PDDPYEQLRAAIEAVFASWNSPRAVAYRRHHGLDDDGGTAVVVQA 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 241 MVFGNSGERSGTGVAFTRNPVTGENQLFGEYLLNAQGEDVVAGIRTPKDIDTLKEQMPDVHQQFVNVTKQLETHYKDLQD 320
Cdd:PRK05878 200 MVFGNLDANSGTGVLFSRNPITGANEPFGEWLPGGQGEDVVSGLVDVAPITALRDEQPAVYDELMAAARTLERLGRDVQD 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 321 IEFTIENGRLYLLQTRNGKRTARAAIKVAVDLVNEGLITKEEAVTQVDVKSIETLLHPNFKEEALKQATVISKmGLPASP 400
Cdd:PRK05878 280 IEFTVESGKLWLLQTRSAKRSAQAAVRLALQLHDEGLIDDAEALRRVTPTHVETLLRPSLQPEARLAAPLLAK-GLPACP 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 401 GAATGKVVFSAEEAKVQAENGDSVILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDveiDTVn 480
Cdd:PRK05878 359 GVVSGTAYTDVDEALDAADRGEPVILVRDHTRPDDVHGMLAAQGIVTEVGGATSHAAVVSRELGRVAVVGCGA---GVA- 434
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1375050723 481 ktvhypngDMLhEGDIISVDGSAGDLYLGEIETVSAEHSD--EFEQFMQWSEEIARLQVRMNAETP 544
Cdd:PRK05878 435 --------AAL-AGKEITVDGYEGEVRQGVLALSAWSESDtpELRELADIAQRISPLRAHASGDYP 491
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-504 |
5.04e-154 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 459.68 E-value: 5.04e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 1 MTKLIYAFDEGQKSMKDLLGGKGANLSEMKRLGLPVPDGFTITTEACIDYLKQGE------------------------- 55
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMTRLGLPVPPGFTITTEAYRRFLEENGleeeirelladldvddvdalaeasa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 56 ---------HLSDEVKSQLHDHLTAFSNRTGKSfssqdhlLLVSVRSGAK------ISMPGMMDTILNLglndenvekla 120
Cdd:COG0574 81 eirelileaPLPEELEEEILAAYAKLEEKFGED-------LLVAVRSSATaedlpdASFAGQMDTVLNV----------- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 121 tktddarfaydcyrrllqmfgdvvygvpmthfdtyfeqykkahqyNSDAditaeglkeiceqykgiylehghkpfpqdpl 200
Cdd:COG0574 143 ---------------------------------------------NGNE------------------------------- 146
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 201 qQLEESIEAVFKSWDNDRARVYRDLNDIPH-DIGTAVNIQEMVFGNsgeRSGTGVAFTRNPVTGEN-QLFGEYLlNAQGE 278
Cdd:COG0574 147 -QLLEAIKAVFASLFTDRAIAYRRHNGIDHdDVGTAVNVQAMVFGN---MSASGVMFTRDPSTGEKdVVYIEAL-NGLGE 221
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 279 DVVAGIRTP------------KDIDTLKEQM----------------------PDVHQQFVNVTKQLETHYKDLQDIEFT 324
Cdd:COG0574 222 DVVAGIVTPdpyyvdkptileRTLGSKAIKMvydggtvevpvppeernrpsltDEEYLELARIALRLEKHYGDPQDIEWA 301
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 325 IENGRLYLLQTRNgkrtaraaIKVAvdlvnEGLITKEeAVTQVDVKSIETLLHPNFKEEALKQATVISKmGLPASPGAAT 404
Cdd:COG0574 302 IDDGKLYILQTRP--------ITVL-----EGLITKE-ALLRVDPAQLDQLLHPRFDPKAKEEGEVLAK-GLPASPGAAS 366
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 405 GKVVFSAEEAK-VQAENGDsvILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDVEidtvnktv 483
Cdd:COG0574 367 GKVVFIADEAElARFQEGV--ILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDAT-------- 436
|
570 580
....*....|....*....|.
gi 1375050723 484 hypngDMLHEGDIISVDGSAG 504
Cdd:COG0574 437 -----RVLKDGDEITVDGTTG 452
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
525-870 |
3.77e-76 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 249.92 E-value: 3.77e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 525 FMQWSEEIARLQVRMNAETPQDIQAGYQFNAKGIGLVRTEHMFFGAERLvemrrfilasnydervealnKIKTYQIEDFE 604
Cdd:pfam02896 10 LPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDEL--------------------PTEDEQFEAYK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 605 AIFKLSSGRPTIVRLLDPPLHEFLPSTEEdiamvadqlnvstahlkrrindLNEVNPMLGHRGCRLAITYPELYEMQVEA 684
Cdd:pfam02896 70 GVLEAMNGRPVTVRTLDIGGDKELPYLEE----------------------PEEMNPFLGWRGIRIGLDRPELFRTQLRA 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 685 ImtsvfnlKKEGITSQPEIMIPLVSTVEEFTTLKSQLVSTIQDLENDMKDKVHYLIGTMIETPRACLIADQLAQQCDFFS 764
Cdd:pfam02896 128 I-------LRASAFGNLRIMFPMVASVEELREAKAIIEEVKEELDAEVGFDKDIKVGIMIEVPSAALLADQLAKEVDFFS 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 765 FGTNDLTQLTYGFSRDDAgKFINVYtesnilqlDPFQTLDHDGVGQLIEIAVTNAKrvnssiKIGVCGELGGDAKSIRRF 844
Cdd:pfam02896 201 IGTNDLTQYTLAVDRDNE-RVAYLY--------DPLHPAVLRLIKEVIRAAHRHGK------WVGICGEMAGDPSAVPLL 265
|
330 340
....*....|....*....|....*.
gi 1375050723 845 NQLDIDYVSCSPFRVPGAILATAQSQ 870
Cdd:pfam02896 266 VGLGLDEFSMSPDSVPRARALLAQID 291
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
4-856 |
5.72e-71 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 250.04 E-value: 5.72e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 4 LIYAFDEGQKSMKDLLGGKGANLSEMKR----LGLPVPDGFTITTEACIDYLKQGEhLSDEVKSQLHDhltafsnrtgks 79
Cdd:TIGR01418 1 LILWLEEVRKDDVPLVGGKNASLGEMIQnlspAGVPVPPGFVVTAEAYRYFLEENG-IAQKIRDLLEE------------ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 80 fssqdhlllvsvrsgakismpgmmdtilnlgLNDENVEKLATKTDDARfaydcyrrllqmfgDVVYGVPMTH------FD 153
Cdd:TIGR01418 68 -------------------------------LDVEDVDALAAASAEIR--------------ELILNTPFPPdleeaiRE 102
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 154 TYFEQYKKAHQYNSDADI----TAEGLKEicEQYKG---IYLEhghkpfpqdpLQQLEESIEAVFKSWD---NDRARVYR 223
Cdd:TIGR01418 103 AYDKLSEDYGKEEADVAVrssaTAEDLPD--ASFAGqqeTYLN----------VTGEEEVLEHVKKCWAslfTDRAISYR 170
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 224 DLNDIPHD-IGTAVNIQEMVfgNSGERSgTGVAFTRNPVTGENQlfgEYLLNAQ---GEDVVAGIRTPK----DIDTLKE 295
Cdd:TIGR01418 171 VSQGFDHEkVAIAVGVQKMV--RSDLGS-SGVMFTIDTETGFKD---AVFIESAwglGEAVVGGAVTPDeyvvFKPTLEQ 244
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 296 QMPDVHQ---------------------QFVNVTK---------------------QLETHYKDLQDIEFTIEN--GRLY 331
Cdd:TIGR01418 245 GKKAILErtlgskkikmvydpdgggvetKIVEVPEeerdafslsdeeilelaklavLIEKHYGRPMDIEWAKDGfdGEIF 324
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 332 LLQTRNGKRTARAaikvavdlvneglitKEEAVTQvdvksietllhpNFKEEALKQATViskMGLPASPGAATGK--VVF 409
Cdd:TIGR01418 325 IVQARPETVQSRK---------------KKENVEE------------RYELKGKGKVLV---TGRAAGPGIASGKvkVIF 374
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 410 SAEEAKvQAENGDsvILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDVEidtvnktvhypngD 489
Cdd:TIGR01418 375 DLKEMD-KFEEGD--ILVTDMTDPDWEPAMKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDAT-------------K 438
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 490 MLHEGDIISVDGSAGD---LYLG----EIETVSAEhsdefeqfmqwSEEIARLQVRMNAETPQDIQAGYQFNAKGIGLVR 562
Cdd:TIGR01418 439 TLKDGMEVTVDCAEGDtgyVYAGklehEVKEVELS-----------NMPVTATKIYMNVGNPEVAFRFAALPNDGVGLAR 507
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 563 TEHMFFGAERlVEMRRFI-------LASNYDERVEALNKIKTYQIEDFEAIFKLSSG---RPTIVRLLDPPLHEFlpste 632
Cdd:TIGR01418 508 IEFIILNWIG-KHPLALIddddlesVEKNEIEELMAGNPRDFFVDKLAEGIAKVAAAfypKPVIVRTSDFKSNEY----- 581
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 633 ediamvadqlnvstAHLKRRIND-LNEVNPMLGHRGCR--LAITYPELYEMQVEAImTSVFNlkKEGITSQpEIMIPLVS 709
Cdd:TIGR01418 582 --------------RNLIGGEEYePDEENPMLGWRGASryYSESYEEAFRLECRAI-KRVRE--EMGLTNV-EVMIPFVR 643
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 710 TVEEfttlkSQLVSTIQDLENDMKDKVHYLIGTMIETPRACLIADQLAQQCDFFSFGTNDLTQLTYGFSRdDAGKFINVY 789
Cdd:TIGR01418 644 TPEE-----GKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDR-DSGLVAHLF 717
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1375050723 790 TESNilqldpfqtldhDGVGQLIEIAVTNAKRVNssIKIGVCGELGGDAKSIRRF-NQLDIDYVSCSP 856
Cdd:TIGR01418 718 DERN------------PAVLRLIEMAIKAAKEHG--KKVGICGQAPSDYPEVVEFlVEEGIDSISLNP 771
|
|
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
1-837 |
8.19e-68 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 241.19 E-value: 8.19e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 1 MTKLIYAFDEGQKSMKDLLGGKGANLSEM----KRLGLPVPDGFTITTEACIDYLKQGehlsdevksqlhdhltafsnrt 76
Cdd:PRK06464 3 MMKYVLWFEELGMEDVPLVGGKNASLGEMisnlSGAGVPVPPGFATTAEAYRYFLEQT---------------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 77 gksfssqdhlllvsvrsgakismpGMMDTILNL--GLNDENVEKLATKTDDARfaydcyrrllqmfgDVVYGVPMThfdT 154
Cdd:PRK06464 61 ------------------------GLNEKIYELldGLDVDDVDALAKAGAQIR--------------QLIIDTPFP---P 99
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 155 YFEQ-----YKKAHQYNSDADI------TAEGLKEIC-----EQY---KGIylehghkpfpqdplQQLEESIEAVFKSWD 215
Cdd:PRK06464 100 DLEQeireaYAKLSAGYGEASVavrssaTAEDLPDASfagqqETFlnvRGI--------------DDVLEAVKECFASLF 165
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 216 NDRARVYRDLNDIPH-DIGTAVNIQEMVfgNSgERSGTGVAFTRNPVTG-ENQLF--GEYLLnaqGEDVVAGIRTPK--- 288
Cdd:PRK06464 166 TDRAISYRVHQGFDHfKVALSAGVQKMV--RS-DLAASGVMFTLDTESGfRDVVFitASWGL---GEMVVQGAVNPDefy 239
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 289 -DIDTLKEQMPDV-------------------------------HQQFV----------NVTKQLETHYKDLQDIEFTIE 326
Cdd:PRK06464 240 vHKPTLKAGKPAIvrrtlgskkikmvyddggehgvktvdvpeeeRNRFSltdeevlelaKQAVIIEKHYGRPMDIEWAKD 319
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 327 --NGRLYLLQTRngkrtaraaikvavdlvneglitkEEAV-TQVDVKSIETllhpnfkEEALKQATVISKmGLPASPGAA 403
Cdd:PRK06464 320 gdDGKLYIVQAR------------------------PETVkSRKEANVLER-------YKLKGQGKVLVE-GRAIGPGIG 367
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 404 TGKV--VFSAEEA-KVQAenGDsvILMRPETSPEdiegMV-----ASeAIVTTHGGMTSHAAVVARGMGKCCVTGCSDVe 475
Cdd:PRK06464 368 SGKVrvILDISEMdKVQP--GD--VLVTDMTDPD----WEpvmkrAS-AIVTNRGGRTCHAAIIARELGIPAVVGTGNA- 437
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 476 idtvnkTvhypngDMLHEGDIISV---DGSAGDLYLGEIETVSAEHSDEfeqfmqwSEEIARLQVRMNAETPQDIQAGYQ 552
Cdd:PRK06464 438 ------T------EVLKDGQEVTVscaEGDTGYVYEGLLEFEVEEVSLE-------EMPETPTKIMMNVGNPERAFDFAA 498
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 553 FNAKGIGLVRTEHMFFGA-----ERLVEMrrfilaSNYDERVEALNKIKTYQIEDFEAIF--KLSSG----------RPT 615
Cdd:PRK06464 499 LPNDGVGLARLEFIINNMigvhpLALLEF------DQQDADLKAEIEELTAGYASPEEFYvdKLAEGiatvaaafypKPV 572
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 616 IVRLLDPPLHEFlpsteediamvadqlnvstAHLKR-RINDLNEVNPMLGHRGCR--LAITYPELYEMQVEAImtsvfnl 692
Cdd:PRK06464 573 IVRLSDFKSNEY-------------------ANLIGgERYEPEEENPMLGFRGASryLSESFREAFALECEAI------- 626
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 693 KK----EGITSQpEIMIPLVSTVEEFTTLKSQLVStiQDL---ENDMKdkvhylIGTMIETPRACLIADQLAQQCDFFSF 765
Cdd:PRK06464 627 KRvreeMGLTNV-EVMIPFVRTVEEAEKVIELLAE--NGLkrgENGLK------VIMMCEIPSNALLAEEFLEYFDGFSI 697
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1375050723 766 GTNDLTQLTYGFSRdDAGKFINVYTEsnilqldpfqtlDHDGVGQLIEIAVTNAKRVNssIKIGVCGELGGD 837
Cdd:PRK06464 698 GSNDLTQLTLGLDR-DSGLVAHLFDE------------RNPAVKKLISMAIKAAKKAG--KYVGICGQAPSD 754
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
444-873 |
1.95e-52 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 192.98 E-value: 1.95e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 444 AIVTTHGGMTSHAAVVARGMGKCCVTGCSDVEidtvnktvhypngDMLHEGDIISVDGSAGDLY-------LGEIETVSA 516
Cdd:COG1080 177 GFVTDLGGRTSHTAILARSLGIPAVVGLGDAL-------------LLVKDGDLVIVDGDAGVVIvnpdeetLAEYRERQA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 517 EHSDEFEQFMQWSEEIA------RLQVRMNAETPQDIQAGYQFNAKGIGLVRTEHMFFGAERLV-EmrrfilasnyDERV 589
Cdd:COG1080 244 EYAAERAELARLRDLPAvtldgvRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPtE----------EEQF 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 590 EAlnkiktYQiedfeAIFKLSSGRPTIVRLLD------PPlheFLPSTEEDiamvadqlnvstahlkrrindlnevNPML 663
Cdd:COG1080 314 EA------YR-----AVAEAMGGRPVTIRTLDiggdkpLP---YLPLPKEE-------------------------NPFL 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 664 GHRGCRLAITYPELYEMQVEAIM-TSVF-NLKkegitsqpeIMIPLVSTVEEFTTLKSQLVSTIQDLEND---MKDKVHy 738
Cdd:COG1080 355 GLRAIRLCLDRPELFRTQLRAILrASAHgNLR---------IMFPMISSVEELRQAKALLEEAKAELRAEgipFDEDIP- 424
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 739 lIGTMIETPRACLIADQLAQQCDFFSFGTNDLTQLTYGFSRDDAgkfiNVyteSNilQLDPFqtldHDGVGQLIEIAVTN 818
Cdd:COG1080 425 -VGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNE----KV---AY--LYDPL----HPAVLRLIKMVIDA 490
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1375050723 819 AKRVNssIKIGVCGELGGDAKSIRRFNQLDIDYVSCSPFRVPG---AILATAQSQAEE 873
Cdd:COG1080 491 AHKAG--KPVGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAvkaIIRRLDLAEARA 546
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
17-357 |
1.17e-50 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 181.25 E-value: 1.17e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 17 DLLGGKGANLSEMK-RLGLPVPDGFTITTEACIDYLKQG---------------------EHLSDEVKS---------QL 65
Cdd:pfam01326 2 NLVGGKGANLGEMLnDAGIPVPPGFAITADAYREFLEENglrekidellkdldvddvdelREASKEIRQlilsaplpeEL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 66 HDHLTAFSNRTGKSFssQDHLLLVSVRSGA------KISMPGMMDTILNLGLNDENVEKlatktddarfaydcyrrllqm 139
Cdd:pfam01326 82 EEAIREAYEELGKKF--GDEPLPVAVRSSAtaedlpDASFAGQQDTYLNVGGNDEVLEA--------------------- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 140 fgdvvygvpmthfdtyfeqykkahqynsdaditaeglkeiceqykgiylehghkpfpqdplqqleesIEAVFKSWDNDRA 219
Cdd:pfam01326 139 -------------------------------------------------------------------IKAVFASLFNDRA 151
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 220 RVYRDLNDIPH-DIGTAVNIQEMVFGNSgersgTGVAFTRNPVTGENqlfGEYLLNA---QGEDVVAGIRTP-------- 287
Cdd:pfam01326 152 IAYRREKGIDHeDVALAVGVQRMVRSDA-----SGVMFSRDPETGFR---DEVLINAswgLGEAVVQGRVTPdefyvfkp 223
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 288 -----------KDI---------DTLKEQMP-DVHQQFV----------NVTKQLETHYKDLQDIEFTIE--NGRLYLLQ 334
Cdd:pfam01326 224 tleilrrtigeKEIkmvydeggeGTKEVEVPeEKRERFSlsdeevlelaRIAKKIEKHYGTPMDIEWAIDgrDGKLYILQ 303
|
410 420
....*....|....*....|...
gi 1375050723 335 TRNGKRTARAAIKVAVDLVNEGL 357
Cdd:pfam01326 304 ARPETVWSEAMEKIAAEILEEGL 326
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
446-876 |
2.77e-36 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 145.32 E-value: 2.77e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 446 VTTHGGMTSHAAVVARGMGKCCVTGcsdveidTVNKTVHYPNGDML---HEGDIISVDGSAGD--LYLGEIETVSAEHSD 520
Cdd:TIGR01417 179 LTDAGGKTSHTAIMARSLEIPAIVG-------TKSVTSQVKNGDTViidGVKGIVIFNPSSETidKYEAKQEAVSSEKAE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 521 EFEQFMQWSEEIARLQVRMNAE--TPQDIQAGYQFNAKGIGLVRTEHMFFGAERLvemrrfilaSNYDERVEAlnkikty 598
Cdd:TIGR01417 252 LAKLKDKPAITLDGHQVELAANigTVDDVEGAERNGGEGIGLFRTEFLYMSRDQL---------PTEEEQFAA------- 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 599 qiedFEAIFKLSSGRPTIVRLLDPPLHEFLPSteediamvadqlnvstahlkrrINDLNEVNPMLGHRGCRLAITYPELY 678
Cdd:TIGR01417 316 ----YKTVLEAMESDAVIVRTLDIGGDKELPY----------------------LNFPKEENPFLGYRAIRLALEREEIL 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 679 EMQVEAIM-TSVF-NLKkegitsqpeIMIPLVSTVEEFTTLKsQLVSTIQDLENDMKDKV--HYLIGTMIETPRACLIAD 754
Cdd:TIGR01417 370 RTQLRAILrASAYgKLR---------IMFPMVATVEEIRAVK-QELEEEKQELNDEGKAFdeNIEVGVMIEIPSAALIAD 439
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 755 QLAQQCDFFSFGTNDLTQLTYGFSRDDAgKFINVYtesnilqlDPFqtldHDGVGQLIEIAVTNAKRVNssIKIGVCGEL 834
Cdd:TIGR01417 440 HLAKEVDFFSIGTNDLTQYTLAVDRGND-LISNLY--------QPY----NPAVLRLIKLVIDAAKAEG--IWVGMCGEM 504
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1375050723 835 GGDAKSIRRFNQLDIDYVSCSPFRVPGAILATAQSQAEESER 876
Cdd:TIGR01417 505 AGDERAIPLLLGLGLRELSMSASSILRIKMIIRKLNIEECKS 546
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
446-839 |
1.03e-26 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 115.88 E-value: 1.03e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 446 VTTHGGMTSHAAVVARGMGKCCVTGcsdveidTVNKTVHYPNGDMLHEGDI---ISVDGSAGdlylgEIETVSAEHsdef 522
Cdd:PRK11177 180 ITDIGGRTSHTSIMARSLELPAIVG-------TGNITKQVKNGDYLILDAVnnqIYVNPTNE-----VIEELKAVQ---- 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 523 EQFMQWSEEIARL-----------QVRM--NAETPQDIQAGYQFNAKGIGLVRTEHMFFGAERL-VEMRRFIlasNYDER 588
Cdd:PRK11177 244 EQYASEKAELAKLkdlpaitldghQVEVcaNIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALpTEEEQFQ---AYKAV 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 589 VEALNkiktyqiedfeaifklssGRPTIVRLLDPPLHEFLPSteediamvadqlnvstahlkrrINDLNEVNPMLGHRGC 668
Cdd:PRK11177 321 AEAMG------------------SQAVIVRTMDIGGDKELPY----------------------MNLPKEENPFLGWRAI 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 669 RLAITYPELYEMQVEAIM-TSVFnlkkegitSQPEIMIPLVSTVEEFTTLKSQLVSTIQDLENDMK--DKvHYLIGTMIE 745
Cdd:PRK11177 361 RIAMDRKEILHDQLRAILrASAF--------GKLRIMFPMIISVEEVRELKAEIEILKQELRDEGKafDE-SIEIGVMVE 431
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 746 TPRACLIADQLAQQCDFFSFGTNDLTQltYGFSRDDAGKFI----NVYTESnILQLdpfqtldhdgVGQLIEIAVTNAKR 821
Cdd:PRK11177 432 TPAAAVIARHLAKEVDFFSIGTNDLTQ--YTLAVDRGNELIshlyNPMSPS-VLNL----------IKQVIDASHAEGKW 498
|
410
....*....|....*...
gi 1375050723 822 VnssikiGVCGELGGDAK 839
Cdd:PRK11177 499 T------GMCGELAGDER 510
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
422-504 |
4.21e-25 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 99.02 E-value: 4.21e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 422 DSVILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDVEIDtvnktvhypngdmLHEGDIISVDG 501
Cdd:pfam00391 4 EGVILVAPDTTPSDTAGLDKAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATIL-------------LKEGDLVTVDG 70
|
...
gi 1375050723 502 SAG 504
Cdd:pfam00391 71 STG 73
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
1-336 |
1.03e-23 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 107.67 E-value: 1.03e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 1 MTKLIYAFDEGQKSMKDLLGGKGANLSEMKRLGLPVPDGFTITTEACIDYLKQgehlsDEVKSQLHDHLTAFSNRTGKSF 80
Cdd:PRK06241 1 MSSYVLDFQEIDKTQLPLVGGKGANLGELSRAGIPVPEGFCVTTEAYKKFLEQ-----NEEFDALLDQLSALKLEDREQI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 81 SsqdhlllvsvRSGAKISmpgmmDTILNLGLNDENVEKLAtktddarfaydcyrRLLQMFG-DVVYGVpmthfdtyfeqy 159
Cdd:PRK06241 76 G----------EISAKIR-----EVIEAIEIPEDIVEAIA--------------AALSKFGeDHAYAV------------ 114
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 160 kkahqyNSDAdiTAEGLKeiceqykgiylehgHKPFP--QDP------LQQLEESIEAVFKSWDNDRARVYRDLNDIPHD 231
Cdd:PRK06241 115 ------RSSA--TAEDLP--------------TASFAgqQDTylnvigKDAILQHIRKCWASLFTERAVIYRIQNGFDHR 172
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 232 -IGTAVNIQEMVFgnsGERSgtGVAFTRNPVTGENQlfgEYLLNAQ---GEDVVAGIRTP------------KDIDTLKE 295
Cdd:PRK06241 173 kVYMSVVVQKMVF---PEAS--GIMFTADPVTGNRK---VLSIDASfglGEALVSGLVSAdtykvregkiidKTIATKKL 244
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1375050723 296 QMPDV-----HQQFVN-------------------VTKQLETHYKDLQDIEFTIENGRLYLLQTR 336
Cdd:PRK06241 245 AIYALkeggtETKEIEpeqqksqtltdeqilelarLGRKIEAHFGCPQDIEWCLADGTFYILQSR 309
|
|
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
444-837 |
4.65e-21 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 98.91 E-value: 4.65e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 444 AIVTTHGGMTSHAAVVARGMGKCCVTGcsdVEIdtvnktvhypNGDMLHEGDIIsVDGSAGDLYLGEIETVSAEH----S 519
Cdd:PRK11061 345 GVVVRDGAANSHAAILVRALGIPTVMG---ADI----------QPSLLHQRLLI-VDGYRGELLVDPEPVLLQEYqrliS 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 520 DEFEQFMQWSEEIA---------RLQVRMNA----ETPQDIQAGyqfnAKGIGLVRTEhmffgaerlvemRRFILASNYD 586
Cdd:PRK11061 411 EEIELSRLAEDDVNlpaqlksgeRIKVMLNAglsaEHEEKLGSR----VDGVGLYRTE------------IPFMLQSGFP 474
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 587 ERVEalnkiktyQIEDFEAIFKLSSGRPTIVRLLD----PPLhEFLPSTEEdiamvadqlnvstahlkrrindlnevNPM 662
Cdd:PRK11061 475 SEEE--------QVAQYQGMLQMFPDKPVTLRTLDigadKQL-PYMPISEE--------------------------NPC 519
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 663 LGHRGCRLAITYPELYEMQVEAImtsvfnLKKEGITSQPEIMIPLVSTVEEFTTLKSQLVSTIQDLENDMKDKVHY-LIG 741
Cdd:PRK11061 520 LGWRGIRITLDQPEIFLIQVRAM------LRANAATGNLSILLPMVTSIDEVDEARRLIDRAGREVEEMLGYEIPKpRIG 593
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 742 TMIETPRACLIADQLAQQCDFFSFGTNDLTQLTYGFSRDDAgKFINVYtESNilqldpfqtldHDGVGQLIEIAVTNAKR 821
Cdd:PRK11061 594 IMIEVPSMVFMLPHLASRVDFISVGTNDLTQYLLAVDRNNT-RVASLY-DSL-----------HPAMLRALKMIADEAEQ 660
|
410
....*....|....*.
gi 1375050723 822 VNssIKIGVCGELGGD 837
Cdd:PRK11061 661 HG--LPVSLCGEMAGD 674
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
401-512 |
2.07e-15 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 78.40 E-value: 2.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 401 GAATGKVVF--SAEEAKVQAENGDsvILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDVEidt 478
Cdd:COG3848 221 GSVTGKAVVarSAEEALEKFEEGD--ILVVPSTDAEFVPAIEKAAGIITEEGGLTSHAAIVGLELGIPVIVGAEGAT--- 295
|
90 100 110
....*....|....*....|....*....|....
gi 1375050723 479 vnktvhypngDMLHEGDIISVDGSAGDLYLGEIE 512
Cdd:COG3848 296 ----------EILKDGQVVTVDAERGVVYRGAVN 319
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
395-504 |
1.45e-11 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 68.14 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 395 GLPASPGAATGK--VVFSAEE-AKVQaengDSVILMRPETSPE--DIEGMVAseAIVTTHGGMTSHAAVVARGMGKCCVT 469
Cdd:PRK08296 502 GFAASPGVVEGParVIRSADElSEVQ----EGEILVCPVTSPSwaPIFAKIK--ATVTDIGGVMSHAAIVCREYGLPAVV 575
|
90 100 110
....*....|....*....|....*....|....*
gi 1375050723 470 GcsdveidTVNKTvhypngDMLHEGDIISVDGSAG 504
Cdd:PRK08296 576 G-------TGNAT------KRIKTGQRLRVDGTKG 597
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
401-514 |
4.66e-09 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 59.94 E-value: 4.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 401 GAATGKVVF---SAEEAKVqaENGDsvILMRPETSPEDIEGMVASEAIVTTHGGMTSHAAVVARGMGKCCVTGCSDVEid 477
Cdd:PRK06354 491 KSVSGKARVaktAAEVAKV--NEGD--ILVTPSTDADMIPAIEKAAAIITEEGGLTSHAAVVGLRLGIPVIVGVKNAT-- 564
|
90 100 110
....*....|....*....|....*....|....*..
gi 1375050723 478 tvnktvhypngDMLHEGDIISVDGSAGDLYLGEIETV 514
Cdd:PRK06354 565 -----------SLIKDGQIITVDAARGVVYSGHASVL 590
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
379-504 |
1.53e-06 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 52.20 E-value: 1.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375050723 379 NFKEEALKQATVIskmGLPASPGAATG--KVVFSAEEAKVqaENGDsvILMRPETSPedieG----MVASEAIVTTHGGM 452
Cdd:PRK06241 757 KYKRENLPAGALI---GLPVSSGVVEGraRVILNPEDADL--EKGD--ILVTAFTDP----GwtplFVSIKGLVTEVGGL 825
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1375050723 453 TSHAAVVARGMGKCCVTGcsdVEidtvNKTVHYPNGDMlhegdiISVDGSAG 504
Cdd:PRK06241 826 MTHGAVIAREYGIPAVVG---VE----NATKLIKDGQR------IRVDGTEG 864
|
|
| |
