|
Name |
Accession |
Description |
Interval |
E-value |
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
2-724 |
0e+00 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 1537.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 2 IDPSLLLDGLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMG 81
Cdd:PRK11773 1 MDVSYLLDSLNDKQREAVAAPLGNMLVLAGAGSGKTRVLVHRIAWLMQVENASPYSIMAVTFTNKAAAEMRHRIEQLLGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 82 SSSGMWNGTFHGICHRILRAHYLDAKLPEDFQIIDSDDQIRLLRRLIKAQNLDEKQWPAKQASWWINGKKDEGLRPNHID 161
Cdd:PRK11773 81 SQGGMWVGTFHGLAHRLLRAHWQDANLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAQWYINGQKDEGLRPQHIQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 162 AYHDPITQTWLKIYSAYQEACDRAGLVDFAEILLRSHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPD 241
Cdd:PRK11773 161 SYGDPVEQTWLKIYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYQERFTHILVDEFQDTNAIQYAWIRLLAGDT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 242 CRVMIVGDDDQSIYGWRGAKIENIQKFLDEFPGASTVRLEQNYRSTKTILQASNELISNNTERMGKELWTDGNDGEPISV 321
Cdd:PRK11773 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIANNNGRLGKELWTDGGDGEPISL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 322 YSAYNELDEARFTVSKIKEWQEKGGALEDTAMLYRNNAQSRVLEEALIQGGLPYRIYGGMRFFERQEIRDALSYLRLMSN 401
Cdd:PRK11773 321 YCAFNELDEARFVVERIKTWQDNGGALSDCAILYRSNAQSRVLEEALLQAGIPYRIYGGMRFFERQEIKDALAYLRLIAN 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 402 RSNDAAFERVVNTPTRGLGDKTLETIRLAARDRGATMWQASIALIEEQVLPGRAAGALSRFIELINALEDDTIELRLHEQ 481
Cdd:PRK11773 401 RNDDAAFERVVNTPTRGIGDRTLDVVRQTARDRQLTLWQACRALLQEKVLAGRAASALQRFIELIDALAQETADMPLHEQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 482 TDHVIKSSGLFAMYEQEKGEKSKARIENLEELVTATRQFEKPEEADEMSMLTAFLTHAALEAGEGQADEFDDAVQLMTLH 561
Cdd:PRK11773 481 TDRVIKDSGLRAMYEQEKGEKGQARIENLEELVTATRQFSYPDEDEDLTPLQAFLSHAALEAGEGQADAHEDAVQLMTLH 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 562 SAKGLEFPMVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMEKLYITYAEMRRLYGQDKYHKPSRFIRELPETC 641
Cdd:PRK11773 561 SAKGLEFPLVFIVGMEEGLFPSQMSLEEGGRLEEERRLAYVGITRAMQKLTLTYAESRRLYGKEVYHRPSRFIREIPEEC 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 642 LDEVRMKAQVSRPASSGRFSQTAVKEnfNETGFSLGSRVKHPKFGEGTIINFEGSGPQSRVQVAFNGEGIKWLVTAYARL 721
Cdd:PRK11773 641 VEEVRLRATVSRPVSHQRMGTPAVEA--NDSGFKLGQRVRHPKFGEGTIVNFEGSGAHARVQVAFQGQGIKWLVAAYAKL 718
|
...
gi 1376820986 722 EQL 724
Cdd:PRK11773 719 EAV 721
|
|
| uvrD |
TIGR01075 |
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, ... |
7-722 |
0e+00 |
|
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130147 [Multi-domain] Cd Length: 715 Bit Score: 1294.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 7 LLDGLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMGSSSGM 86
Cdd:TIGR01075 1 LLDGLNDKQREAVAAPPGNLLVLAGAGSGKTRVLTHRIAWLLSVENASPHSIMAVTFTNKAAAEMRHRIGALLGTSARGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 87 WNGTFHGICHRILRAHYLDAKLPEDFQIIDSDDQIRLLRRLIKAQNLDEKQWPAKQASWWINGKKDEGLRPNHIDAYHDP 166
Cdd:TIGR01075 81 WIGTFHGLAHRLLRAHHLDAGLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAMWYINNQKDEGLRPSHIQAFDNP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 167 ITQTWLKIYSAYQEACDRAGLVDFAEILLRSHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDCRVMI 246
Cdd:TIGR01075 161 VERTWIKIYQAYQEACDRAGLVDFAELLLRAHELLRNKPHILQHYQERFTHILVDEFQDTNKIQYAWIRLLAGNTGNVMI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 247 VGDDDQSIYGWRGAKIENIQKFLDEFPGASTVRLEQNYRSTKTILQASNELISNNTERMGKELWTDGNDGEPISVYSAYN 326
Cdd:TIGR01075 241 VGDDDQSIYGWRGAQVENIQKFLKDFPGAETIRLEQNYRSTANILAAANALIANNDERLGKNLWTDGEVGEPISLYSAFN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 327 ELDEARFTVSKIKEWQEKGGALEDTAMLYRNNAQSRVLEEALIQGGLPYRIYGGMRFFERQEIRDALSYLRLMSNRSNDA 406
Cdd:TIGR01075 321 ELDEARFVVSRIKTWQRNGGALDECAVLYRSNAQSRVLEEALLQASIPYRIYGGMRFFERQEIKDALAYLRLIANRNDDA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 407 AFERVVNTPTRGLGDKTLETIRLAARDRGATMWQASIALIEEQVLPGRAAGALSRFIELINALEDDTIELRLHEQTDHVI 486
Cdd:TIGR01075 401 AFERVINTPTRGIGDRTLDVVRQAARDRGLTLWQAARELTQEKVLAGRAASALQRFVELIEALANETADMPLHVQTDHVI 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 487 KSSGLFAMYEQEKGEKSKARIENLEELVTATRQFEKPEEADEMSMLTAFLTHAALEAGEGQADEFDDAVQLMTLHSAKGL 566
Cdd:TIGR01075 481 KDSGLREMYQQEKGEKGQARIENLEELVTATRQFSLPENDEDMTPLTAFLSHAALEAGEGQADAGQDAVQLMTLHSAKGL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 567 EFPMVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMEKLYITYAEMRRLYGQDKYHKPSRFIRELPETCLDEVR 646
Cdd:TIGR01075 561 EFPLVFLVGMEEGMFPSQMSLDEGGRLEEERRLAYVGITRAMQKLTITYAETRRLYGKEVYHIPSRFIRELPEECLHEVR 640
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1376820986 647 MKAQVSRPASSGRFSQTAVKEnFNETGFSLGSRVKHPKFGEGTIINFEGSGPQSRVQVAFNGEGIKWLVTAYARLE 722
Cdd:TIGR01075 641 LRAQVSRPTNLGRVGTPSVDE-INDAGFKLGQRVRHPKFGEGTIINAEGSGEHSRLQIAFQGQGIKWLVAAYAKLE 715
|
|
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
7-715 |
0e+00 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 923.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 7 LLDGLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMGSSSGM 86
Cdd:COG0210 3 LLAGLNPEQRAAVEHPEGPLLVLAGAGSGKTRVLTHRIAYLIAEGGVDPEQILAVTFTNKAAREMRERIEALLGRLARGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 87 WNGTFHGICHRILRAHYLDAKLPEDFQIIDSDDQIRLLRRLIKAQNLDEKQWPAKQASWWINGKKDEGLRPNHIDAY--H 164
Cdd:COG0210 83 WVGTFHSLALRILRRHAELLGLPPNFTILDGDDQLRLIKELLKELGLDEKRFPPRELLSLISRAKNEGLTPEELAELlaA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 165 DPITQTWLKIYSAYQEACDRAGLVDFAEILLRSHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDCRV 244
Cdd:COG0210 163 DPEWRAAAELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVDEYQDTNPAQYELLRLLAGDGRNL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 245 MIVGDDDQSIYGWRGAKIENIQKFLDEFPGASTVRLEQNYRSTKTILQASNELISNNTERMGKELWTDGNDGEPISVYSA 324
Cdd:COG0210 243 CVVGDDDQSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANNPGRLGKNLWTDNGEGEKVRLYVA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 325 YNELDEARFTVSKIKEWQEKGGALEDTAMLYRNNAQSRVLEEALIQGGLPYRIYGGMRFFERQEIRDALSYLRLMSNRSN 404
Cdd:COG0210 323 PDEEEEARFVADEIRELHEEGVPLSDIAVLYRTNAQSRALEEALRRAGIPYRVVGGLRFYERAEIKDLLAYLRLLANPDD 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 405 DAAFERVVNTPTRGLGDKTLETIRLAARDRGATMWQASIALIEEQVLPGRAAGALSRFIELINALEDDTIELRLHEQTDH 484
Cdd:COG0210 403 DVALLRILNVPRRGIGAATLERLREAAREEGISLLEALRDLGELAGLSGRAAKALRRFAELLEALRAAAERLPLEELLEA 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 485 VIKSSGLFAMYEQEKGEKSKARIENLEELVTATRQFekpEEADEMSMLTAFLTHAALEAGEGQADEFDDAVQLMTLHSAK 564
Cdd:COG0210 483 LLDESGYEEELREEAGEEAERRLENLEELVDAAARF---EERNPGASLEAFLEELALLSDLDAADEDEDAVTLMTLHAAK 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 565 GLEFPMVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMEKLYITYAEMRRLYGQDKYHKPSRFIRELPETCLDE 644
Cdd:COG0210 560 GLEFPVVFLVGLEEGLFPHQRSLDDEEELEEERRLFYVAITRARERLYLTYAASRRLWGETQDNEPSRFLDELPEELLEW 639
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1376820986 645 VRMKAQVSRPASSGRFSQTAVKENFNE-------TGFSLGSRVKHPKFGEGTIINFEGSGPQSRVQVAFNGEGIKWLV 715
Cdd:COG0210 640 VRPKAEAAAAAASAAAALPASGAGAAAlaagaaaAAAAAGGGAAVAGAGLGRAAAAGGADGGAAGAGGGLAAVALTVL 717
|
|
| pcrA |
TIGR01073 |
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. ... |
7-722 |
0e+00 |
|
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273429 [Multi-domain] Cd Length: 726 Bit Score: 734.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 7 LLDGLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMGSSSGM 86
Cdd:TIGR01073 1 LLAHLNPEQREAVKTTEGPLLIMAGAGSGKTRVLTHRIAHLIAEKNVAPWNILAITFTNKAAREMKERVEKLLGPVAEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 87 WNGTFHGICHRILRAHYLDAKLPEDFQIIDSDDQIRLLRRLIKAQNLDEKQWPAKQASWWINGKKDEGLRPNHI----DA 162
Cdd:TIGR01073 81 WISTFHSMCVRILRRDIDRIGINRNFSIIDPTDQLSLMKTILKDKNLDPKKFEPRSILGTISNAKNELLPPEDFakeaTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 163 YHDpitQTWLKIYSAYQEACDRAGLVDFAEILLRSHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDC 242
Cdd:TIGR01073 161 YFE---KVVAEVYQEYQKRLLRNNALDFDDLIMTTINLFQRVPDVLEYYQRKFQYIHVDEYQDTNRAQYTLVRLLASRFR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 243 RVMIVGDDDQSIYGWRGAKIENIQKFLDEFPGASTVRLEQNYRSTKTILQASNELISNNTERMGKELWTDGNDGEPISVY 322
Cdd:TIGR01073 238 NLCVVGDADQSIYGWRGADIQNILSFEKDYPNATTILLEQNYRSTKNILQAANEVIEHNSNRKPKNLWTENSSGDKITYY 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 323 SAYNELDEARFTVSKIKEWQEKG-GALEDTAMLYRNNAQSRVLEEALIQGGLPYRIYGGMRFFERQEIRDALSYLRLMSN 401
Cdd:TIGR01073 318 EADTERDEAQFVAGEIDKLVKNGeRKYGDFAILYRTNAQSRVFEETLLKANIPYKIVGGLKFYDRKEIKDILAYLRVIAN 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 402 RSNDAAFERVVNTPTRGLGDKTLETIRLAARDRGATMWQASIALIEEQVLPGRAAGALSRFIELINALEDDTIELRLHEQ 481
Cdd:TIGR01073 398 PDDDLSLLRIINVPKRGIGASSLEKIVNYALELNISLFEAIGEIDEIGGLAAKSANALLAFATMIENLRQQQEYLSPTEL 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 482 TDHVIKSSGLFAMYEQEKGEKSKARIENLEELVTATRQFEkpEEADEMSmLTAFLTHAALEAGEGQADEFD--DAVQLMT 559
Cdd:TIGR01073 478 VEEVLDKSGYREMLKAEKTEEAQSRLENLDEFLSVTKEFE--DESEDKS-LIDFLTDLALVSDLDELEETEegGAVTLMT 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 560 LHSAKGLEFPMVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMEKLYITYAEMRRLYGQDKYHKPSRFIRELPE 639
Cdd:TIGR01073 555 LHAAKGLEFPVVFLIGMEEGVFPHSRSLMDEKELEEERRLAYVGITRAEEELYLTHATMRTLFGRIQMNPPSRFLNEIPA 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 640 TCLDEVR---------------MKAQVSRPASSGrfSQTAVKenfnETGFSLGSRVKHPKFGEGTIINFEGSGPQSRVQV 704
Cdd:TIGR01073 635 ELLETAStgrrtgatdpkgpsiRQAGASRPTTSQ--PTAGGD----TLSWAVGDRVNHKKWGIGTVVSVKGGGDDQELDI 708
|
730
....*....|....*...
gi 1376820986 705 AFNGEGIKWLVTAYARLE 722
Cdd:TIGR01073 709 AFPSIGVKRLLAAFAPIE 726
|
|
| rep |
TIGR01074 |
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. ... |
10-652 |
2.12e-172 |
|
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130146 [Multi-domain] Cd Length: 664 Bit Score: 509.29 E-value: 2.12e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 10 GLNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRI-EELMMGSSSGMWN 88
Cdd:TIGR01074 1 KLNPQQQEAVEYVTGPCLVLAGAGSGKTRVITNKIAYLIQNCGYKARNIAAVTFTNKAAREMKERVaKTLGKGEARGLTI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 89 GTFHGICHRILRAHYLDAKLPEDFQIIDSDDQIRLLRRLIKAQnLDEKQWPAKQASWWINGKKDEGLRPNHIDAY-HDPI 167
Cdd:TIGR01074 81 STFHTLGLDIIKREYNALGYKSNFSLFDETDQLALLKELTEGL-IKDDKDLLDKLISTISNWKNDLLTPEQALASaRGER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 168 TQTWLKIYSAYQEACDRAGLVDFAEILLRSHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDCRVMIV 247
Cdd:TIGR01074 160 EQTFAHCYALYQAHLRAYNALDFDDLILLPTLLLQQNEEVRNRWQNKIRYLLVDEYQDTNTSQYELVKLLVGDRARFTVV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 248 GDDDQSIYGWRGAKIENIQKFLDEFPGASTVRLEQNYRSTKTILQASNELISNNTERMGKELWTDGNDGEPISVYSAYNE 327
Cdd:TIGR01074 240 GDDDQSIYSWRGARPENLVLLKEDFPQLKVIKLEQNYRSTGRILKAANILIANNPHVFEKKLFSELGYGEKIKVIECNNE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 328 LDEARFTVSKI-KEWQEKGGALEDTAMLYRNNAQSRVLEEALIQGGLPYRIYGGMRFFERQEIRDALSYLRLMSNRSNDA 406
Cdd:TIGR01074 320 EHEAERIAGEIiAHKLVNKTQYKDYAILYRGNHQSRLLEKALMQNRIPYKLSGGTSFFSRPEIKDLLSYLRLLVNPDDDA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 407 AFERVVNTPTRGLGDKTLETIRLAARDRGATMWQASIALIEEQVLPGRAAGALSRFIELINALEDDTIELRLHEQTDHVI 486
Cdd:TIGR01074 400 AFLRIVNTPKREIGPATLEKLGELAMERNKSLFTASFDMGLLQTLSGRGYESLQRFTDWLVEIRRLAERSEPIEAVRSLI 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 487 KSSGLFA-MYEQEKGEKS-KARIENLEELVTA-TRQFEKPEEADEMSMLTAFLTHAALEAGEGQADEFD-DAVQLMTLHS 562
Cdd:TIGR01074 480 EDIDYENwLYETSPSPKAaEMRMKNVNTLFSWfKEMLEGDEEDEPMTLTQVVTRLTLRDMLERGEDEEElDQVQLMTLHA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 563 AKGLEFPMVFMVGVEEGMFPSQMSAEEaGRLEEERRLCYVGMTRAMEKLYITYAEMRRLYGQDKYHKPSRFIRELPETCL 642
Cdd:TIGR01074 560 SKGLEFPYVFIVGMEEGILPHQSSIEE-DNVEEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLDELPQEDL 638
|
650
....*....|
gi 1376820986 643 DEVRMKAQVS 652
Cdd:TIGR01074 639 QWEGDDPVVS 648
|
|
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
11-639 |
1.09e-137 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 420.40 E-value: 1.09e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 11 LNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRIEELM-MGSSSGMWNG 89
Cdd:PRK10919 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVAQTLgRKEARGLMIS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 90 TFHGICHRILRAHYLDAKLPEDFQIIDSDDQIRLLRRLiKAQNLDEKQWPAKQASWWINGKKDEGLRPNHIDAY----HD 165
Cdd:PRK10919 83 TFHTLGLDIIKREYAALGMKSNFSLFDDTDQLALLKEL-TEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAGakgeRD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 166 PITQTWLKIYSAYQEACDragLVDFAEILLRSHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDCRVM 245
Cdd:PRK10919 162 RIFAHCYGLYDAHLKACN---VLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 246 IVGDDDQSIYGWRGAKIENIQKFLDEFPGASTVRLEQNYRSTKTILQASNELISNNTERMGKELWTDGNDGEPISVYSAY 325
Cdd:PRK10919 239 VVGDDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVLSAN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 326 NELDEARFTVSK------IKEWQEKggaleDTAMLYRNNAQSRVLEEALIQGGLPYRIYGGMRFFERQEIRDALSYLRLM 399
Cdd:PRK10919 319 NEEHEAERVTGEliahhfVNKTQYK-----DYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVL 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 400 SNRSNDAAFERVVNTPTRGLGDKTLETIRLAARDRGATMWQASIALIEEQVLPGRAAGALSRFIELINALEddtielRLH 479
Cdd:PRK10919 394 TNPDDDSAFLRIVNTPKREIGPATLQKLGEWAMTRNKSLFTASFDMGLSQTLSGRGYESLTRFTHWLAEIQ------RLA 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 480 EQTDHVIKSSGLFAM-YEQ---EKGEKSKA---RIENLEELVTATRQFEKPEEADEMSMLTAFLTHAALE--AGEGQADE 550
Cdd:PRK10919 468 EREPVAAVRDLIHGIdYESwlyETSPSPKAaemRMKNVNQLFSWMTEMLEGSELDEPMTLTQVVTRFTLRdmMERGESEE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 551 FDDAVQLMTLHSAKGLEFPMVFMVGVEEGMFPSQMSAEEaGRLEEERRLCYVGMTRAMEKLYITYAEMRRLYGQDKYHKP 630
Cdd:PRK10919 548 ELDQVQLMTLHASKGLEFPYVYLVGMEEGLLPHQSSIDE-DNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEP 626
|
....*....
gi 1376820986 631 SRFIRELPE 639
Cdd:PRK10919 627 SRFLLELPQ 635
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
11-273 |
1.17e-108 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 330.75 E-value: 1.17e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 11 LNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMGSS-SGMWNG 89
Cdd:pfam00580 1 LNPEQRKAVTHLGGPLLVLAGAGSGKTRVLTERIAYLILEGGIDPEEILAVTFTNKAAREMKERILKLLGKAElSELNIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 90 TFHGICHRILRAHYLDAKLPEDFQIIDSDDQIRLLRRLIKAQ--NLDEKQWPAKQASWWINGKKDEGLRPNHIDAYH-DP 166
Cdd:pfam00580 81 TFHSFCLRILRKYANRIGLLPNFSILDELDQLALLKELLEKDrlNLDPKLLRKLELKELISKAKNRLLSPEELQQGAaDP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 167 ITQTWLKIYSAYQEACDRAGLVDFAEILLRSHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDCRVMI 246
Cdd:pfam00580 161 RDKLAAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPIQYRLLKLLAGGHENLFL 240
|
250 260
....*....|....*....|....*..
gi 1376820986 247 VGDDDQSIYGWRGAKIENIQKFLDEFP 273
Cdd:pfam00580 241 VGDPDQSIYGFRGADIENILKFEKDFP 267
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
14-636 |
9.79e-103 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 334.24 E-value: 9.79e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 14 KQREAVAAPLE-NLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRI-----EELMMGSSSGMW 87
Cdd:COG1074 8 DAQRRALDPLGgSVLVEASAGSGKTYTLVARYLRLLLERGLDPEEILVVTFTRAAAAEMRERIrerlaEAADLEDPDLEE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 88 N-------------------GTFHGICHRILRAHYLDAKLPEDFQIID-------------------------------- 116
Cdd:COG1074 88 LararrrlaralenldraaiSTIHSFCQRLLREFAFEAGLDPNFELLDdaeallleeavddllreayapldalalarlld 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 117 ----SDDQIR-LLRRLIKAQNldEKQWPAKQASWWINGKKDEGLRPNHIDAYHDPITQTWLK--------------IYSA 177
Cdd:COG1074 168 afgrDDDSLEeLLLALYKLRS--RPDWLEELAELDEALEALREALLKAKEALAALREALAAAaapllaallrllaaVLAR 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 178 YQEACDRAGLVDFAEILLRSHELLRDKKH--IREHYQARFKHILVDEFQDTNNIQYAWLRMMAG----PDCRVMIVGDDD 251
Cdd:COG1074 246 YERRKRERGLLDFDDLLHRALRLLRDEDApwVAERLRERYRHILVDEFQDTSPLQWEILRRLAGealaDGRTLFLVGDPK 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 252 QSIYGWRGAKIENIQKFLDEFPG---ASTVRLEQNYRSTKTILQASNEL--------------ISNNTERMGK----ELW 310
Cdd:COG1074 326 QSIYRFRGADPELFLEARRALEGrvdGERLTLTTNFRSTPEVVDAVNALfaqlmgagfgeipyEPVEALRPGAypavELW 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 311 TDGNDGEPISVYSAYneldEARFTVSKIKEWQEKGGALE---------DTAMLYRNNAQSRVLEEALIQGGLPYRIYGGM 381
Cdd:COG1074 406 PLEPDDVSEEDARER----EARAVAARIRRLLAEGTTVEgggrpvrpgDIAVLVRTRSEAAAIARALKAAGIPVAASDRL 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 382 RFFERQEIRDALSYLRLMSNRSNDAAFERVVNTPTRGLGDKTLEtiRLAARDRGATMWQasiALieeqvlpgRAAGALSR 461
Cdd:COG1074 482 SLFESPEVRDLLALLRALLNPEDDLALAAVLRSPLFGLSDEDLA--ALAADRKGESLWE---AL--------RAYERLAR 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 462 FIELINALEDDTIELRLHEQTDHVIKSSGLFAMY-EQEKGEKSKARIENLEELVTATRQFEKPEEADEMSMLtAFLTHAA 540
Cdd:COG1074 549 ALERLRALRELARRLGLAELLERLLEETGLLERLlALPGGERRLANLLHLDELLQLALEYEQTGGPGLAGFL-RWLERLI 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 541 LEAGEGQA---DEFDDAVQLMTLHSAKGLEFPMVFMvgveegmfPSQMSAEEAGRLEEERRLCYVGMTRAMEKLYITYAE 617
Cdd:COG1074 628 EDGGDEEKrrlESDADAVRIMTIHKSKGLEFPVVFL--------PALRERARAEELAEELRLLYVALTRARDRLVLSGAV 699
|
730
....*....|....*....
gi 1376820986 618 mrrlyGQDKYHKPSRFIRE 636
Cdd:COG1074 700 -----KKKDAEKESSWLAR 713
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
278-617 |
4.50e-92 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 292.00 E-value: 4.50e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 278 VRLEQNYRSTKTILQASNELISNNTERM----GKELWTDGNDGEPISVYSAYNELDEARFTVSKIKEWQEKGGALEDTAM 353
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRAtiypKKILAETVEDGEKIKIIEAETEEEEAEWIALEIKKLVARDEKYNDIAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 354 LYRNNAQSRVLEEALIQGGLPYRIYGGMRFFERQEIRDALSYLRLMSNRSNDAAFERVVNTPTRGLGDKTLETIRLAARD 433
Cdd:pfam13361 81 LTRSNSDADLIEEALKKLGIPYFVVGQTKFFRREEIKDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERIREYKKR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 434 -----------------------------------RGATMWQASIALIEEQVLPGRA--AGALSRFIELINALEDDTiel 476
Cdd:pfam13361 161 glrlsdfinpdtltygdpfvialeqdnivvfdvetTGLDTTEDEIIQIAAIKLNKKGvvIESFERFLRLKKPVGDSL--- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 477 rlheqtdHVIKSSGLFamyEQEKGEKSKA-------RIENLEELVTATRQFEKPEEADEMSM-LTAFLTHAALEAGEGQA 548
Cdd:pfam13361 238 -------QVHGFSDEF---LQENGETPAEalrdfleKLENLRELYSILREYDDIEETPEPEDaLRNFLEIATLSNSELEG 307
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1376820986 549 DEFDDAVQLMTLHSAKGLEFPMVFMVGVEEGMFPSQMSAEEAGRLEEERRLCYVGMTRAMEKLYITYAE 617
Cdd:pfam13361 308 SDIKERIPIMTIHQAKGLEFDTVFLAGLEEGIFPSYRSIKDEGNLEEERRLFYVAITRAKKRLYISYSK 376
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
12-284 |
1.36e-82 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 260.14 E-value: 1.36e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 12 NDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRIEELMMGSS-SGMWNGT 90
Cdd:cd17932 1 NPEQREAVTHPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGVPPERILAVTFTNKAAKEMRERLRKLLGEQLaSGVWIGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 91 FHGICHRILRAHYldaklpedfqiidsddqirllrrlikaqnldekqwpakqaswwingkkdeglrpnhidayhdpitqt 170
Cdd:cd17932 81 FHSFALRILRRYG------------------------------------------------------------------- 93
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 171 wlkiysayqeacdraglvDFAEILLRSHELLRDKKHIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDCRVMIVGDD 250
Cdd:cd17932 94 ------------------DFDDLLLYALELLEENPDVREKLQSRFRYILVDEYQDTNPLQYELLKLLAGDGKNLFVVGDD 155
|
250 260 270
....*....|....*....|....*....|....
gi 1376820986 251 DQSIYGWRGAKIENIQKFLDEFPGASTVRLEQNY 284
Cdd:cd17932 156 DQSIYGFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| addA_Gpos |
TIGR02785 |
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, ... |
13-613 |
1.51e-36 |
|
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274299 [Multi-domain] Cd Length: 1230 Bit Score: 147.93 E-value: 1.51e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 13 DKQREAVAAPLENLLILAGAGSGKTRVLVHRIawLQSVeqASPFSI---MSVTFTNKAAAEMRGRIEELMMGSSSGMWN- 88
Cdd:TIGR02785 4 DEQWQAIYTRGQDILVSASAGSGKTAVLVERI--IRKI--TRGVDVdrlLVVTFTNAAAREMKERIAEALEKELVQEPNs 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 89 ---------------GTFHGICHRILRAHYLDAKLPEDFQIIDSDDQIRL------------------------------ 123
Cdd:TIGR02785 80 khlrrqlallntaniSTLHSFCLKVIRKHYYLLDLDPSFRILTDTEQLLLikevlddvfeeeyykedkeaffelvdnfsg 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 124 ------LRRLIK-------------------------------------------------------------------- 129
Cdd:TIGR02785 160 drsddgLRDLILqlydfsrstpnpekwlnnlaeayevkekftieslklqqqikellkneleglqeklqralelfmaedgl 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 130 ----------AQNLDEK-QWPAKQASW-----------WINGK---KDEGLRP--------------------------- 157
Cdd:TIGR02785 240 aprlenfqldLQNIDELiQESLAQADWnelrkavaafkFKNLKaakGDEEDADlleeadklreeakkqleklktdyftrs 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 158 --NHIDAYHD--PITQTWLKIYS----AYQEACDRAGLVDFAEILLRSHELL----RDKKHIREHYQARFKHILVDEFQD 225
Cdd:TIGR02785 320 eeDHLRIMQEmkPVVKTLVQLVKdfieRFGAEKREKNILDFSDLEHYALQILtnenESPSEAAEFYREKFHEVLVDEYQD 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 226 TNNIQYA---WLRMMAGPDCRVMIVGDDDQSIYGWRGAK----IENIQKFLDEFPGAST-VRLEQNYRSTKTILQASNEL 297
Cdd:TIGR02785 400 TNLVQESilqLVKRGPEEEGNLFMVGDVKQSIYRFRQADpllfLEKYHRFAQEGEEHGKrIDLAENFRSRAEVLDTTNFL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 298 IS------------------------------NNTERMGKELWTDGNDGEPiSVYSAYNELD----EARFTVSKIKE--- 340
Cdd:TIGR02785 480 FKqlmdeevgeidydeeaqlkfgaakypenpdNKTEELLYEKLLIEEAEEE-EIDEEAEILDkaqqEATMVAERIKAlik 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 341 -----WQEKGG-----ALEDTAMLYRNNAQSRVLEEALIQGGLPYRIYGGMRFFERQEIRDALSYLRLMSNRSNDAAFER 410
Cdd:TIGR02785 559 egfkvYDKKTGtyrpvTYRDIVILTRSRGWNLQIMEEFKKYGIPVFANDAENYFQTTEVRVMLSLLRVIDNPYQDIPLVA 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 411 VVNTPTRGLGDKTLETIRLAARDrgATMWQASIALIEEQVLPGRAAGALSRFIELINALEDDTIELRLHEQTDHVIKSSG 490
Cdd:TIGR02785 639 VLRSPIVGFDENELALIRLENKD--SSYYEAVKDYVKAGLIEDELYEKLNTFLDSLQKWREFARTHSVSELIWKIYNDTG 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 491 LfamYEQEKG-EKSKARIENLEELVTATRQFEKpeeademsmlTAF--------LTHAALEAGE--GQA---DEFDDAVQ 556
Cdd:TIGR02785 717 Y---YDYVGGlPGGKQRQANLYALYERARQYES----------TSFkglfqfirFIERMQERQKdlASAvavGEAENAVR 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 557 LMTLHSAKGLEFPMVFMVGV-----------------------------EEGMFPSQmsAEEAGR-------LEEERRLC 600
Cdd:TIGR02785 784 LMTIHKSKGLEFPVVFVLGMgkqfnkqdlnssylldrqlglgikyidpqERLSYPSL--PKVAIKqkmkrelLSEEMRVL 861
|
890
....*....|...
gi 1376820986 601 YVGMTRAMEKLYI 613
Cdd:TIGR02785 862 YVALTRAKEKLIL 874
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
286-615 |
8.96e-31 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 117.72 E-value: 8.96e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 286 STKTILQASNELISNNTERMGKELWTDGNDGEPISVYSAYNELDEARFTVSKIKEWQEKGG-ALEDTAMLYRNNAQSRVL 364
Cdd:cd18807 1 STKNILDAANSLIKQNKNRPKKPLKAGNKSGGPVELLLAKDEADEAKAIADEIKRLIESGPvQYSDIAILVRTNRQARVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 365 EEALIqgglpyriyggmrfferqeirdalsylrlmsnrsndaafervvntptrglgdktletirlaardrgatmwqasia 444
Cdd:cd18807 81 EEALR--------------------------------------------------------------------------- 85
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 445 lieeqvlpgraagalsrfielinaleddtielrlheqtdhvikssglfamyeqekgekskarienleelvtatrqfekpe 524
Cdd:cd18807 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 525 eademsmltaflthaaleagegqadefddaVQLMTLHSAKGLEFPMVFMVGVEEGMFPSQMSAEEAG----RLEEERRLC 600
Cdd:cd18807 86 ------------------------------VTLMTIHASKGLEFPVVFIVGLGEGFIPSDASYHAAKedeeRLEEERRLL 135
|
330
....*....|....*
gi 1376820986 601 YVGMTRAMEKLYITY 615
Cdd:cd18807 136 YVALTRAKKELYLVG 150
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
27-639 |
5.64e-28 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 120.62 E-value: 5.64e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 27 LILAGAGSGKTRVLVHRIAwlQSVEQASPFsIMSVTFTNKAAAEmrgrIEELMMGSSSGMWNG---TFHGICHRILRAHY 103
Cdd:COG3857 2 FILGRAGSGKTTYLLEEIK--EELKEGKPI-ILLVPEQMTFQAE----RALLKRLGLGGSIRAqvlSFSRLAWRVLQETG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 104 LDAKlpedfQIIDSDDQIRLLRRLIKaQNLDEKQWPAKQASW---------WINGKKDEGLRPNHIDAYHDPITQ--TWL 172
Cdd:COG3857 75 GATR-----PLLSDAGKRMLLRKILE-EHKDELKVFARAADKpgfieqlaeLITELKRYGITPEDLEEAAELLKEklRDL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 173 -KIYSAYQEACdRAGLVDFAEILlrshELLRDKkhIREHYQARFKHILVDEFQDTNNIQYAWLRMMAGPDCRVMIVGDDD 251
Cdd:COG3857 149 aLIYEAYEEKL-AGRYIDSEDLL----RLLAEK--LEKSEFLEGAEIYIDGFTDFTPQELELLEALLKKAKEVTITLTLD 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 252 QSIYGWRGAKIENIQKFLDEfpgASTVRLEQNYRSTKTILQASNELISNNTErmgkelwtdgNDGEPISVYSAYNELDEA 331
Cdd:COG3857 222 PDELDLFSATGETYERLLEL---AKENGVEVEFKKSPELAHLERNLFAYPPE----------EEPEGIEIIEAANRRAEV 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 332 RFTVSKIKEW-QEKGGALEDTAMLYRN-NAQSRVLEEALIQGGLPYRIYGGMRFFERQEIRDALSYLRLMSNRSNDAAFE 409
Cdd:COG3857 289 EAVAREIRRLvREEGYRYRDIAVVVRDlEAYAPLIERVFAEYGIPYFIDEKRPLSHHPLVELILSLLELVRSNFRYEDVF 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 410 RVVNTP-TRGLGDKTLETIRLAARDRG--ATMWQaSIALIEEQVLPGRAAGALSRFIELINALEDDTIELR--------L 478
Cdd:COG3857 369 RLLKTGlLRPLSREEIDRLENYVLAYGirGRRWL-ERYLEEEEELTDEEEEDLERLNELRDRLLEPLLPLRerlkkaktV 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 479 HEQTD---HVIKSSGLFAMYEQEKGEKSKARIENLEE-------LVTATRQFEKPEEADEMSMLTAF--LTHAALEAGEG 546
Cdd:COG3857 448 REWAEalyEFLEELGVPEKLEEWREAEEAGDLEEAREheqawnaLIELLDELVEVLGDEKLSLEEFLriLESGLEELTFG 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 547 QADEFDDAVQLMTLHSAKGLEFPMVFMVGVEEGMFPSQMSAE------------EAG---------RLEEERRLCYVGMT 605
Cdd:COG3857 528 LIPPSLDQVQVGGLDRARGLDFKAVFVLGLNEGVFPARPREDgllsdeererlnELGlelpptsreRLLEERFLFYRALT 607
|
650 660 670
....*....|....*....|....*....|....
gi 1376820986 606 RAMEKLYITYAEMRRlygQDKYHKPSRFIRELPE 639
Cdd:COG3857 608 RASERLYLSYPLADE---EGKALLPSPLIDRLRE 638
|
|
| recB |
TIGR00609 |
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with ... |
27-617 |
2.40e-26 |
|
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with potent ATP-dependent exodeoxyribonuclease activity. Ejection of RecD, as occurs at chi recombinational hotspots, cripples exonuclease activity in favor of recombinagenic helicase activity. All proteins in this family for which functions are known are DNA-DNA helicases that are used as part of an exonuclease-helicase complex (made up of RecBCD homologs) that function to generate substrates for the initiation of recombination and recombinational repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273172 [Multi-domain] Cd Length: 1087 Bit Score: 115.60 E-value: 2.40e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 27 LILAGAGSGKTrvlvHRIA--WLQSVEQASPFS---IMSVTFTNKAAAEMRGRI---------------------EELMM 80
Cdd:TIGR00609 13 LIEASAGTGKT----FTIAqlYLRLLLEGGPLTveeILVVTFTNAATEELKTRIrgrihqalralkaaltsqelpEPLKE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 81 GSSSGMWNG------------------TFHGICHRILRAHYLDAKLPEDFQIIDSDDQIRLL------RRLIKAQNLDEK 136
Cdd:TIGR00609 89 AIQDEKVKQaitrlrnalatmdeaaiyTIHGFCQRMLEQHAFESDEIFDVELIEDESLLLAEitkdfwRRNFYNLPFDIA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 137 Q---------------------------WPAKQAswwingkKDEGLRPNHIDAYHD----------PITQTWLK------ 173
Cdd:TIGR00609 169 QivlktkkspqavltqiladlllqsylaFPSPPL-------DLEQLIKWHEQIYKDldkldhavfeEIDKLNAErnnlfc 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 174 -----IYSAYQEA-------CDRAGLVDFAEILLRSHELLRDKKH------IREHYQArfkhILVDEFQDTNNIQYAWL- 234
Cdd:TIGR00609 242 lkdrvFLTLLKEVqeelkkeKKRRREIGFDDLLSRLETALKSAEGeklaqaIREQYPI----ALIDEFQDTDPQQYRIFs 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 235 RMMAGPDCRVMI-VGDDDQSIYGWRGAKIENIQKFLDEFPGASTvrLEQNYRSTKTILQASNELISNNTERM-------- 305
Cdd:TIGR00609 318 KLFIAQKETSLFlIGDPKQAIYSFRGADIFTYLQAKSKADARYT--LGTNWRSTPALVGSLNKLFSLISNPFlekpifip 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 306 ----GKE----LWTDGNDGEPISVYSayneLDEARFTVSKIKEWQEKGGALEDTAMLyrNNAQSRVLEEALIQGGLPYRI 377
Cdd:TIGR00609 396 vlahQKNskgsFVINGQEQPPIHFFT----TEVESEGVDDYRQTIAQKCAREIALWL--ASAALGLANFIATFGGRPLRA 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 378 yGGMRFF--ERQE---IRDALSYLRLMSNRSNDaafERVVntptrglgDKTLETIRLaardrgatmwqasIALIEEQVLP 452
Cdd:TIGR00609 470 -GDIAVLvrGRKEanqIRKALKKAQIPSVYLSD---KSSV--------FATEEAQEL-------------LALLEALLEP 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 453 GRA----AGALSRF---------IELINALEDDTIELRLHEQTDHVIKsSGLFAMY--------------EQEKGEKSKA 505
Cdd:TIGR00609 525 ENEgtlrAALASSIfglsaleleTLNQDEITWERVVEKFREYHDIWRK-IGVLAMFqrlmlekgigerllSQPGGERILT 603
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 506 RIENLEELVTATRQFEKpeeaDEMSMLTAFLTHAALE-AGEGQA---DEFDDAVQLMTLHSAKGLEFPMVFMVGV----- 576
Cdd:TIGR00609 604 NLLHLAELLQEAAHQER----NKLSLLRWLEDQISNEeEEEEEIirlESDAELVKIVTIHKSKGLEYPIVFLPFItdakk 679
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 1376820986 577 ------------EEGMFPSQMSAEEAG-----RLEEERRLCYVGMTRAMEKLYITYAE 617
Cdd:TIGR00609 680 snfaslhdqhshEYQLYDFNQSEENQKlarveRLAEDLRLLYVALTRAKKQLFIGIAP 737
|
|
| addA_alphas |
TIGR02784 |
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, ... |
177-614 |
5.37e-26 |
|
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274298 [Multi-domain] Cd Length: 1135 Bit Score: 114.78 E-value: 5.37e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 177 AYQEACDRAGLVDFAEILLRSHELLRDKKhirEHYQARFK------HILVDEFQDTNNIQYAWLRMMA-----GPDCR-- 243
Cdd:TIGR02784 350 RYARLKKARGLLDFNDLIERTVALLARPG---AGAWVHYKldrgidHILVDEAQDTSPEQWDIIQALAeeffsGEGARsg 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 244 ----VMIVGDDDQSIYGWRGAKIENIQKFLDEFPGAST--------VRLEQNYRSTKTILQASNELISNNTERMG----- 306
Cdd:TIGR02784 427 vertIFAVGDEKQSIYSFQGADPERFAEERREFSRKVRavgrkfedLSLNYSFRSTPDVLAAVDLVFADPENARGlsads 506
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 307 -----------------------------KELWTDGNDGEPISvySAYNELdeARFTVSKIKEWQEKGGALE-------- 349
Cdd:TIGR02784 507 dapvheafrddlpgrvdlwdliskeegeePEDWTDPVDELGER--APEVRL--AERIAAEIRAWLDRGTPIPgrgravrp 582
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 350 -DTAMLYRNNAQsrvLEEALIQG----GLPyrIYGGMRFFERQEI--RDALSYLRLMSNRSNDAAFERVVNTPTRGLGDK 422
Cdd:TIGR02784 583 gDILVLVRKRDA---FFSALIRAlkrrGIP--VAGADRLKLTSHIavKDLMALGRFVLQPEDDLSLAALLKSPLFGLDED 657
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 423 TLetIRLAARDRGATMWQASialieeqvlpGRAAGALSRFIELINALEDDTIELRLHEqtdhvikssgLFAMYEQEKGEK 502
Cdd:TIGR02784 658 DL--FRLAAGRSGGSLWAAL----------RRREAEFAATLAVLRDWLSLADFLTPFE----------FYARLLGRDGGR 715
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 503 SK--ARI-----ENLEELVTATRQFEKPEEADemsmLTAFLthAALEAGE----GQADEFDDAVQLMTLHSAKGLEFPMV 571
Cdd:TIGR02784 716 RKllARLgaeaeDILDEFLSQALAYERTGLPG----LQAFL--SWLEADDpeikREMDQARDEVRVMTVHGAKGLEAPVV 789
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1376820986 572 FMVGVEEGMFPSQ---------------------------MSAEEAGRL-----EEERRLCYVGMTRAMEKLYIT 614
Cdd:TIGR02784 790 FLVDTGSKPFASQraplllatggsggkaplwrpasafdpsLSAAARERLkeraeDEYRRLLYVAMTRAEDRLIVC 864
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
11-314 |
1.72e-23 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 105.80 E-value: 1.72e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 11 LNDKQREAVAAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRGRIEELMmgSSSGMWNGT 90
Cdd:PRK11054 197 LNPSQARAVVNGEDSLLVLAGAGSGKTSVLVARAGWLLARGQAQPEQILLLAFGRQAAEEMDERIRERL--GTEDITART 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 91 FHGICHRILRAhyLDAKLPEdFQIIDSDDQIRllRRLI-----------KAQNLDEKQWPAKQASW-------WINGKKD 152
Cdd:PRK11054 275 FHALALHIIQQ--GSKKVPV-ISKLENDSKAR--HALLiaewrkqcsekKAQAKGWRQWLTEELQWdvpegnfWDDEKLQ 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 153 EGLRP--------------------NHIDAYHDPITQTWLKI----YSAYQEACDRAGLVDFAEILLRSHELLRDKKHIR 208
Cdd:PRK11054 350 RRLASrlerwvslmrmhggsqaemiAQAPEEVRDLFQKRLKLmaplLKAWKKALKAENAVDFSGLIHQAVNYLEKGRFIS 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 209 EhyqarFKHILVDEFQDtnnIQYAWLRMMAG-----PDCRVMIVGDDDQSIYGWRGAKIENIQKFLDEFpGASTV-RLEQ 282
Cdd:PRK11054 430 P-----WKHILVDEFQD---ISPQRAALLAAlrkqnSQTTLFAVGDDWQAIYRFSGADLSLTTAFHERF-GEGDRcHLDT 500
|
330 340 350
....*....|....*....|....*....|....
gi 1376820986 283 NYRSTKTILQASNELISNNTERMGKEL--WTDGN 314
Cdd:PRK11054 501 TYRFNSRIGEVANRFIQQNPHQLKKPLnsLTKGD 534
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
25-284 |
1.51e-20 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 87.54 E-value: 1.51e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 25 NLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSIMSVTFTNKAAAEMRgrieelmmgsssgmwngtfhgichrilrahyl 104
Cdd:cd17914 1 LSLIQGPPGTGKTRVLVKIVAALMQNKNGEPGRILLVTPTNKAAAQLD-------------------------------- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 105 daklpedfqiidsddqirllrrlikaqnldekqwpakqaswwingkkdeglrpnhidayhdpitqtwlkiysayqeacdr 184
Cdd:cd17914 --------------------------------------------------------------------------------
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 185 aglvdfaeillrshellrdkkhirehyqarfkHILVDEFQDTNNIQYAWLRMMAGPDCRVMIVGDDDQSIYGWRGAKIEN 264
Cdd:cd17914 49 --------------------------------NILVDEAAQILEPETSRLIDLALDQGRVILVGDHDQLGPVWRGAVLAK 96
|
250 260
....*....|....*....|....*
gi 1376820986 265 -----IQKFLDEFPGASTVRLEQNY 284
Cdd:cd17914 97 icneqSLFTRLVRLGVSLIRLQVQY 121
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
30-613 |
1.28e-16 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 84.25 E-value: 1.28e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 30 AGAGSGKTRVLVHR-IAWLqsVEQASPFSIMSVTFTNKAAAEMRGRI---------------------------EELMMG 81
Cdd:PRK13909 5 ASAGSGKTFALSVRfLALL--FKGANPSEILALTFTKKAANEMKERIidtllnlekekeeselneleeklglskEELLNK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 82 SSSGMWN--------GTFHGICHRILRAHYLDAKLPEDFqIIDSDDQIRLLRRLIKAQNLDEKQWPAKQASWWINGK--- 150
Cdd:PRK13909 83 RDKVYQEflnselkiSTIDAFFQKILRKFCLNLGLSPDF-SIKEDTKEELNEKFLSALSKEELLELLAFIKQCESKKnns 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 151 ----------KDEGLRP---------------------------NHIDAYHDPITQ--------------TWL------- 172
Cdd:PRK13909 162 ffelleklyeKNNELKLfekaknpiefdeekfleelrslkqqiqSIETASKNAKKAfkkedfeellnsskTWLekeseyr 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 173 -------------------------------------KIYSAYQEACDRA----GLVDFAEILLRSHELLRDKKHIREHY 211
Cdd:PRK13909 242 yfkklyneeldaefeelknalkryydakenyklsklfKLLQLYKEAKNELnkkkNALDFDDISKKVYELLGEEEIDKDFL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 212 ----QARFKHILVDEFQDTNNIQYAWLR-----MMAG---PDCR-VMIVGDDDQSIYGWRGAKIENIQKFLDEFPGASTV 278
Cdd:PRK13909 322 yfrlDSKISHILIDEFQDTSVLQYKILLplideIKSGegqKKFRsFFYVGDVKQSIYRFRGGKKELFDKVSKDFKQKVDN 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 279 rLEQNYRSTKTILQASNELISNNTERMGKELWTDGNDGEPISVYSAYNELDE-ARFTVSKIKEWQEKGGALEDTAML-YR 356
Cdd:PRK13909 402 -LDTNYRSAPLIVDFVNEVFKKKYKNYKTQYAEQHKSGGYVEVVEVADESEElLEQLLQEIQFLLEKGIDPDDIAILcWT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 357 NNAQSRV---LEEALiqgGLPYRIYGGMRFFERQEIR---DALSYLRLMSNRSNDAAFERVVNTPTRGLGD-----KTLE 425
Cdd:PRK13909 481 NDDALEIkefLQEQF---GIKAVTESSAKLINQPEVKaliEALKYCLFGEEIYKHNVLKLLGKEPDKIPSFlpkeeSVAE 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 426 TIRLAARDRGatmwqasiaLIEEQVLpgraagalsRFIELINaleddtielrlheqtdhvikssglfamyeqekgekska 505
Cdd:PRK13909 558 FVKKLIEELK---------LYDENLL---------KFLELAS-------------------------------------- 581
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 506 RIENLEELVTATRQFEKPeeademsmltaflthAALEAGEGqadefddaVQLMTLHSAKGLEFPMV-------------- 571
Cdd:PRK13909 582 GYEDIEEFLFKLEPCDKE---------------IASEESKG--------VQIMTVHKSKGLEFEHVivcdrlgkpnsdss 638
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 572 ---FMVGVEEGM---------------FPSQMSAEEAGRLEEERRLCYVGMTRAMEKLYI 613
Cdd:PRK13909 639 nllFEYDGIELWqiyyrikgrenfdkdYARALEKEKALKYEEEINVLYVAFTRAKNSLIV 698
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
15-130 |
3.71e-15 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 72.64 E-value: 3.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 15 QREAV--AAPLENLLILAGAGSGKTRVLVHRIAWLQSVEQAsPFSIMSVTFTNKAAAEMRgrieELMMGSSSgmwngTFH 92
Cdd:pfam13245 1 QREAVrtALPSKVVLLTGGPGTGKTTTIRHIVALLVALGGV-SFPILLAAPTGRAAKRLS----ERTGLPAS-----TIH 70
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1376820986 93 GIC--HRILRAHYL---DAKLPEDFQIID--SDDQIRLLRRLIKA 130
Cdd:pfam13245 71 RLLgfDDLEAGGFLrdeEEPLDGDLLIVDefSMVDLPLAYRLLKA 115
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
198-346 |
2.65e-12 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 70.28 E-value: 2.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 198 HELLRDKKHIREhyqarFKHILVDEFQDTNNIQYAWLrMMAGPDCRVMIVGDDDQSIYGWRGAkiENIQKFLDEFPG--A 275
Cdd:COG3973 458 AELLGGPDRTWT-----YGHVVVDEAQDLSPMQWRVL-KRRFPSASFTIVGDLAQAIHPYRGA--ESWEEVLEPLGGdrA 529
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1376820986 276 STVRLEQNYRSTKTILQASNELIsnntermgKELWTDGN-------DGEPISVYSAYNELDEARFTVSKIKEWQEKGG 346
Cdd:COG3973 530 RLVELTKSYRSTAEIMEFANRVL--------RAAGPDLPppesvrrHGEPPRVVRVPSEAELAAAVVEAVRELLAEGE 599
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
13-622 |
2.92e-12 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 69.86 E-value: 2.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 13 DKQREAVAAPL--ENLLILAGAGSGKTRVLVHRIAWLQSVEQASPFSimsVTFTNKA-AAEMRGRIEE-LMMGSSSGMWN 88
Cdd:COG3972 161 DLQQERIARSIpdGPQRIRGVAGSGKTVLLAAKAAYLALKHPGWRIL---VTCFNRSlADHLRDLIPRfLRRFSNGEPED 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 89 ----GTFHGICHRILRAHyldaklpedfqiidsddqirllrrlikaqnldekqwpakqaswwiNGKKDEGLRPNhidayh 164
Cdd:COG3972 238 nvklIVFHAWGGKLLKQY---------------------------------------------GIPPLTFSQPN------ 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 165 dpitqtwlkiySAYQEACDRAglvdFAEILLRSHEllrdkkhirehyqARFKHILVDEFQDTNNIQYaWL--RMMAGPDC 242
Cdd:COG3972 267 -----------EAFDEACKAL----LEAIQGEIIP-------------PIYDAILIDEAQDFEPEFL-RLlyQLLKPPKK 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 243 RVMIVGDDDQSIYGWRGAKIENIQKFLDEfpgasTVRLEQNYRSTKTILQASNELISNNTErmgkelwtdgndgePISVY 322
Cdd:COG3972 318 RLIWAYDEAQNIYGRKIPSAGGIPAGIGR-----DTILKKNYRNTRPILTFAHAFGMGLLR--------------PPGLL 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 323 SAYNELDEARFTVSKIKEwqekggaledtamlyrnnaqSRVLEEALIQGGLPyriyggmrfferqeirdalsylrlmsnr 402
Cdd:COG3972 379 QGDAEDYEVERPGDKVTL--------------------IRPPEPAGRKGPLP---------------------------- 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 403 sndaafeRVVNTPTRglgdktletirlaardrgatmwQASIALIEEQVlpgraagalsrfielINALEDDTIELrlheqT 482
Cdd:COG3972 411 -------EFKKYDDR----------------------AEELEAIAEEI---------------KKNLRDEGLRP-----S 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 483 DHVIKSSGLFAMYEQEkgekskarienlEELVTATRQFEKPeeademsmltAFLTHAALEAgegqaDEF--DDAVQLMTL 560
Cdd:COG3972 442 DIAVIYLGNNEAKELG------------DRLAAALERQGID----------SYIAGARSDP-----NFFwkDGGVTISTI 494
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1376820986 561 HSAKGLEFPMVFMVGVEEgmfpsqmsAEEAGRLEEERRLCYVGMTRAMEKLYITY--AEMRRLY 622
Cdd:COG3972 495 HRAKGLEAPVVIIVGLDQ--------LAKGESLERLRNLLYVAMTRARGWLVVSGsgESMAELY 550
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
207-607 |
9.86e-11 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 65.38 E-value: 9.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 207 IREhyqaRFKHILVDEFQDTNNIQYAWLRMMAG--PDCRVMIVGDDDQSIYGWRGAKIENIQKFLDEFPGASTvrLEQNY 284
Cdd:PRK10876 374 IRT----RYPVAMIDEFQDTDPQQYRIFRRIYRhqPETALLLIGDPKQAIYAFRGADIFTYMKARSEVSAHYT--LDTNW 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 285 RSTKTILQASNELIS---------------------NNTERM---GKE-----LWTdgNDGEPISVySAYNELdEARFTV 335
Cdd:PRK10876 448 RSAPGMVNSVNKLFSqtddpflfreipfipvkaagkNQALRFvvkGETqpamkFWL--MEGEGVGV-GDYQQT-MAQQCA 523
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 336 SKIKEWQEKGgaLEDTAMLYRNNaQSRVLEEALIQggLPYRiyggmrffERQE---IRDALSYLRL----MSNRsnDAAF 408
Cdd:PRK10876 524 AQIRDWLQAG--QRGEALLMNGD-DSRPVRASDIT--VLVR--------SRQEaalIRDALTLLAIpsvyLSNR--DSVF 588
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 409 ErvvntptrglgdkTLEtirlaARDrgaTMW--QASIALIEEQVLpgRAAGALSRFieLINALEDDtiELRLHEQT-DHV 485
Cdd:PRK10876 589 E-------------TLE-----AQE---MLWllQAVLAPERERTL--RSALATSMM--GLDALDID--ALNNDERAwDAL 641
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 486 IKSsglFAMYEQEKGEK----------SKARI-ENL-----------------EELVTATRQFEKpEEAdemsmLTAFLT 537
Cdd:PRK10876 642 VEE---FDGYRQIWRKRgvlpmlralmSARNIaENLlataggerrltdilhigELLQEASSQLDS-EHA-----LVRWLA 712
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376820986 538 HAALEAgEGQAD------EFD-DAVQLMTLHSAKGLEFPMVFMVGV------EEGMFPSQMS---------AEEAGRL-E 594
Cdd:PRK10876 713 QQILEP-DSQASsqqlrlESDkHLVQIVTIHKSKGLEYPLVWLPFItnfrvqDQAFYHDRHSfeavldlnaAEESVALaE 791
|
490
....*....|....*...
gi 1376820986 595 EER-----RLCYVGMTRA 607
Cdd:PRK10876 792 EERlaedlRLLYVALTRS 809
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
25-91 |
1.65e-09 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 54.83 E-value: 1.65e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1376820986 25 NLLILAGAGSGKTRVLVHRIAWLQSveqaSPFSIMSVTFTNKAAAEMRGRIEE--LMMGSSSGMWNGTF 91
Cdd:cd17912 1 NILHLGPTGSGKTLVAIQKIASAMS----SGKSVLVVTPTKLLAHEILIVIDEiq*ILDPAAGWAWATR 65
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
548-614 |
2.35e-09 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 54.75 E-value: 2.35e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1376820986 548 ADEFD-DAVQLMTLHSAKGLEFPMVFMVGVEEGMfpsqmsaeeagrleEERRLCYVGMTRAMEKLYIT 614
Cdd:cd18786 35 LDEFDlQLVGAITIDSSQGLTFDVVTLYLPTANS--------------LTPRRLYVALTRARKRLVIY 88
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
558-614 |
3.33e-09 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 52.96 E-value: 3.33e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1376820986 558 MTLHSAKGLEFPMVFMVGVEEGmfpsqmsaeEAGRLEEERRLCYVGMTRAMEKLYIT 614
Cdd:pfam13538 5 LTVHKAQGSEFPAVFLVDPDLT---------AHYHSMLRRRLLYTAVTRARKKLVLV 52
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
545-613 |
3.53e-04 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 39.85 E-value: 3.53e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1376820986 545 EGQADEFDDAVQL--MTLHSAKGLEFPMVFMVGVEEGMFpsqmsaeeagrleEERRLCYVGMTRAMEKLYI 613
Cdd:cd18809 21 KGGVDALNERLQAyaMTIHKSQGSEFDRVIVVLPTSHPM-------------LSRGLLYTALTRARKLLTL 78
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
11-72 |
1.12e-03 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 42.27 E-value: 1.12e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1376820986 11 LNDKQREAV--AAPLENLLILAG-AGSGKTRVLVHRIAWLqsveQASPFSIMSVTFTNKAAAEMR 72
Cdd:COG0507 125 LSDEQREAValALTTRRVSVLTGgAGTGKTTTLRALLAAL----EALGLRVALAAPTGKAAKRLS 185
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
558-613 |
3.54e-03 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 40.73 E-value: 3.54e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1376820986 558 MTLHSAKGLEFPMVFMVgveegmFPSQMSAEEAgrleeeRRLCYVGMTRAMEKLYI 613
Cdd:COG0507 445 ITVHKSQGSTFDRVILV------LPSEHSPLLS------RELLYTALTRARELLTL 488
|
|
| |
